Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

Sies, H. (2017) · Redox Biology

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 2,148

Function and regulation of cullin–RING ubiquitin ligases

Petroski, M. D., & Deshaies, R. J. (2005) · Nature Reviews Molecular Cell Biology

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 2,148

Necroptosis and its role in inflammation

Pasparakis, M., & Vandenabeele, P. (2015) · Nature

Cell death mechanisms and regulationImmune Response and Inflammation

Cited by 2,148

Qualimap 2: advanced multi-sample quality control for high-throughput sequencing data

Okonechnikov, K., Conesa, A., & García-Alcalde, F. (2016) · Bioinformatics

Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics

Cited by 2,145

ROS and the DNA damage response in cancer

Srinivas, U. S., Tan, B. W. Q., Vellayappan, B. A., & Jeyasekharan, A. D. (2019) · Redox Biology

Redox biology and oxidative stressDNA Repair Mechanisms

Cited by 2,144

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

Wang, R., Dillon, C. P., Shi, L. Z., Milasta, S., Carter, R., Finkelstein, D., McCormick, L. L., Fitzgerald, P., Chi, H., Munger, J., et al. (2011) · Immunity

Cancer, Hypoxia, and MetabolismT-cell and B-cell Immunology

Cited by 2,140

Active Genes Are Tri-Methylated at K4 of Histone H3

Santos-Rosa, H., Schneider, R., Bannister, A. J., Sherriff, J., Bernstein, B. E., Emre, N. C. T., Schreiber, S. L., Mellor, J., & Kouzarides, T. (2002) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 2,138

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer

Glaviano, A., Foo, A. S. C., Lam, H. Y., Yap, K. C. H., Jacot, W., Jones, R. H., Eng, H., Nair, M. G., Makvandi, P., Geoerger, B., et al. (2023) · Molecular Cancer

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 2,138

Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants

Tong, A. H. Y., Evangelista, M., Parsons, A. B., Xu, H., Bader, G. D., Pagé, N., Robinson, M., Raghibizadeh, S., Hogue, C. W. V., Bussey, H., et al. (2001) · Science

Fungal and yeast genetics researchBioinformatics and Genomic Networks

Cited by 2,138

The PI3K–AKT network at the interface of oncogenic signalling and cancer metabolism

Hoxhaj, G., & Manning, B. D. (2020) · Nature Reviews Cancer

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 2,137

Transmission Electron Microscopy of Shape-Controlled Nanocrystals and Their Assemblies

Wang, Z. L. (2000) · The Journal of Physical Chemistry B

Advanced Electron Microscopy Techniques and ApplicationsElectron and X-Ray Spectroscopy Techniques

Cited by 2,137

Clustal Omega for making accurate alignments of many protein sequences

Sievers, F., & Higgins, D. G. (2018) · Protein Science

Genomics and Phylogenetic StudiesProtein Structure and Dynamics

Cited by 2,137

Gut microbiome alterations in Alzheimer’s disease

Vogt, N. M., Kerby, R. L., Dill-McFarland, K. A., Harding, S. J., Merluzzi, A. P., Johnson, S. C., Carlsson, C. M., Asthana, S., Zetterberg, H., Blennow, K., et al. (2017) · Scientific Reports

Gut microbiota and healthAlzheimer's disease research and treatments

Cited by 2,137

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

Du, P., Zhang, X., Huang, C.-C., Jafari, N., Kibbe, W. A., Hou, L., & Lin, S. M. (2010) · BMC Bioinformatics

Epigenetics and DNA MethylationGene expression and cancer classification

Cited by 2,136

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

Usoskin, D., Furlan, A., Islam, S., Abdo, H., Lönnerberg, P., Lou, D., Hjerling-Leffler, J., Haeggström, J., Kharchenko, O., Kharchenko, P. V., et al. (2015) · Nature Neuroscience

Single-cell and spatial transcriptomicsIon Channels and Receptors

Cited by 2,136

Interleukin-8 as a macrophage-derived mediator of angiogenesis

Koch, A. E., Polverini, P. J., Kunkel, S. L., Harlow, L. A., DiPietro, L. A., Elner, V. M., Elner, S. G., & Strieter, R. M. (1992) · Science

Angiogenesis and VEGF in CancerChemokine receptors and signaling

Cited by 2,135

RNA sequencing: advances, challenges and opportunities

Ozsolak, F., & Milos, P. M. (2011) · Nature Reviews Genetics

Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics

Cited by 2,135

Rate of de novo mutations and the importance of father’s age to disease risk

Kong, A., Frigge, M. L., Masson, G., Besenbacher, S., Sulem, P., Magnusson, G., Gudjonsson, S. A., Sigurdsson, A., Jonasdottir, A., Jonasdottir, A., et al. (2012) · Nature

Genomics and Rare DiseasesEvolution and Genetic Dynamics

Cited by 2,134

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

Castello, A., Fischer, B., Eichelbaum, K., Horos, R., Beckmann, B. M., Strein, C., Davey, N. E., Humphreys, D. T., Preiss, T., Steinmetz, L. M., et al. (2012) · Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 2,132

PANDAseq: paired-end assembler for Illumina sequences

Masella, A. P., Bartram, A. K., Truszkowski, J. M., Brown, D. G., & Neufeld, J. D. (2012) · BMC Bioinformatics

Genomics and Phylogenetic StudiesAlgorithms and Data Compression

Cited by 2,132

Sequence Analysis of the Genome of the Unicellular Cyanobacterium Synechocystis sp. Strain PCC6803. II. Sequence Determination of the Entire Genome and Assignment of Potential Protein-coding Regions

Kaneko, T., Sato, S., Kotani, H., Tanaka, A., Asamizu, E., Nakamura, Y., Miyajima, N., Hirosawa, M., Sugiura, M., Sasamoto, S., et al. (1996) · DNA Research

Genomics and Phylogenetic StudiesPhotosynthetic Processes and Mechanisms

Cited by 2,132

Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

Lupiáñez, D. G., Kraft, K., Heinrich, V., Krawitz, P., Brancati, F., Klopocki, E., Horn, D., Kayserili, H., Opitz, J. M., Laxova, R., et al. (2015) · Cell

Genomics and Chromatin DynamicsGenomic variations and chromosomal abnormalities

Cited by 2,132

Genome-wide detection and characterization of positive selection in human populations

The International HapMap Consortium, Sabeti, P. C., Varilly, P., Fry, B., Lohmueller, J., Hostetter, E., Cotsapas, C., Xie, X., Byrne, E. H., McCarroll, S. A., et al. (2007) · Nature

Forensic and Genetic ResearchGenetic Associations and Epidemiology

Cited by 2,131

Inferring Regulatory Networks from Expression Data Using Tree-Based Methods

Huynh-Thu, V. A., Irrthum, A., Wehenkel, L., & Geurts, P. (2010) · PLoS ONE

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 2,131