Increasing Adiposity: Consequence or Cause of Overeating?
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Mechanisms linking diet quality to metabolic risk appear to include calorie-independent effects of different types of foods on satiety, glucose-insulin responses, liver fat synthesis, adipocyte function, visceral adiposity, brain craving and reward, and metabolic expenditure.
“Mechanisms appear to include calorie-independent effects of different types of foods on satiety, glucose-insulin responses,45 liver fat synthesis,46 adipocyte function,47 visceral adiposity,48 brain craving and reward,49 and even metabolic expenditure.50”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [47]
Cites
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BackgroundResultInfluentialEbbeling, C. B., Feldman, H. A., Klein, G. L., Wong, J. M. W., Bielak, L., Steltz, S. K., Luoto, P. K., Wolfe, R. R., Wong, W. W., & Ludwig, D. S. (2018) · BMJ · doi:10.1136/bmj.k4583 · Cited by 274 · see citing works
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The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed
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Self-citationGenetic evidence that carbohydrate-stimulated insulin secretion leads to obesity
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- Authors
- Ludwig, D. S., & Friedman, M. I.
- Affiliations
- Boston Children's Hospital (US)
- Nutrition Science Initiative, San Diego, California
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2014-06-04
- Volume
- 311
- Issue
- 21
- Pages
- 2167
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2013758022
- Cited by
- 151
- References
- 8
- Citations by year
- 2026: 6 · 2025: 3 · 2024: 5 · 2023: 10 · 2022: 11 · 2021: 7 · 2020: 14 · 2019: 20 · 2018: 18 · 2017: 20 · 2016: 11 · 2015: 16 · 2014: 10
- FWCI
- 18.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (K24DK082730, P30DK040561)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Keywords
- adiposity, obesity, fat gain
- MeSH terms
- Diet, Humans, Hunger, Hyperphagia, Obesity, Weight Loss, Adiposity
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