Cited by 343Advanced Sensor and Energy Harvesting MaterialsSilk-based biomaterials and applicationsNanomaterials and Printing Technologies

Plasticizing Silk Protein for On‐Skin Stretchable Electrodes

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Chen, Geng, Matsuhisa, Naoji, Liu, Zhiyuan, Qi, Dianpeng, Cai, Pingqiang, Jiang, Ying, Wan, Changjin, Cui, Yajing +6 more·2018·Advanced Materials

Abstract

Soft and stretchable electronic devices are important in wearable and implantable applications because of the high skin conformability. Due to the natural biocompatibility and biodegradability, silk protein is one of the ideal platforms for wearable electronic devices. However, the realization of skin‐conformable electronic devices based on silk has been limited by the mechanical mismatch with skin, and the difficulty in integrating stretchable electronics. Here, silk protein is used as the substrate for soft and stretchable on‐skin electronics. The original high Young's modulus (5–12 GPa) and low stretchability (<20%) are tuned into 0.1–2 MPa and > 400%, respectively. This plasticization is realized by the addition of CaCl 2 and ambient hydration, whose mechanism is further investigated by molecular dynamics simulations. Moreover, highly stretchable (>100%) electrodes are obtained by the thin‐film metallization and the formation of wrinkled structures after ambient hydration. Finally, the plasticized silk electrodes, with the high electrical performance and skin conformability, achieve on‐skin electrophysiological recording comparable to that by commercial gel electrodes. The proposed skin‐conformable electronics based on biomaterials will pave the way for the harmonized integration of electronics into human.

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Authors
Chen, G., Matsuhisa, N., Liu, Z., Qi, D., Cai, P., Jiang, Y., Wan, C., Cui, Y., Leow, W. R., Liu, Z., Gong, S., Zhang, K., Cheng, Y., & Chen, X.
Affiliations
  • Nanyang Technological University (SG)
  • Agency for Science, Technology and Research (SG)
  • Procter and Gamble Singapore Innovation Center 70 Biopolis Street 138547 Singapore
  • Soochow University (CN)
Corresponding author
  • Cheng, Yuan
  • Chen, Xiaodong
Venue
Advanced Materials
Publisher
Wiley
Published
2018-03-30
Volume
30
Issue
21
Pages
e1800129-e1800129
ISSN
  • 0935-9648 (ISSN-L)
  • 1521-4095
OpenAlex
W2795210588
Cited by
343
References
64
Citations by year
2026: 19 · 2025: 33 · 2024: 51 · 2023: 37 · 2022: 49 · 2021: 50 · 2020: 53 · 2019: 37 · 2018: 14
FWCI
15.38
Type
journal article
Language
en
Open access
Locations
  • Advanced Materials (publishedVersion)
  • PubMed (publishedVersion)
  • DR-NTU (Nanyang Technological University) (submittedVersion)
Funders
  • National Research Foundation Singapore (NRF2016NRF‐NRF1001‐21)
  • Ministry of Education - Singapore (MOE2014‐T2‐2‐140, MOE2015‐T2‐2‐60)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
  • Physical Sciences › Materials Science › Biomaterials › Silk-based biomaterials and applications
  • Physical Sciences › Engineering › Electrical and Electronic Engineering › Nanomaterials and Printing Technologies
Keywords
silk proteins, plasticization, stretchable electronics, wearable electronics, calcium chloride, Young's modulus, thin film metallization, electrophysiological recording, biomaterial substrates
MeSH terms
Biocompatible Materials, Electrodes, Humans, Skin, Silk, Elastic Modulus

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