The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Recent Advances on Activatable NIR‐II Fluorescence Probes for Biomedical Imaging
Abstract
Newly emerging fluorescence imaging in the second near‐infrared window (NIR‐II, 1000–1700 nm) permits visualization of deep anatomical features with unprecedented spatial resolution due to its minimized autofluorescence, optical scattering and absorption of tissue, and increased applicable power at longer wavelengths than the traditional NIR (NIR‐I, 650–900 nm) fluorescence imaging. Compared with “always‐on” NIR‐II fluorescence probes, activatable NIR‐II fluorescence probes that can change their fluorescence signals by pathologic parameters stimuli, hold great promise for providing high target‐to‐background ratio, significantly improving specificity and sensitivity of early disease detection. Additionally, such probes provide an excellent opportunity to understand the underlying pathological mechanism at the molecular level in order to optimize therapeutic interventions. Here, the recent advances in the development of activatable NIR‐II fluorescence probes for bioimaging and biosensing are reviewed. The photochemical design mechanisms and biomedical applications of these probes are described in detail. Moreover, the present challenges to completely exhibit the potential of activatable NIR‐II fluorescence probes for optical theranostics in life science are also discussed. Finally, the future perspective is further analyzed.
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Cited by
Advanced Fluorescence Imaging Technology in the Near-Infrared-II Window for Biomedical Applications
Li, C., Chen, G., Zhang, Y., Wu, F., & Wang, Q. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.0c07022 · Cited by 1,037
Liu, S., Ou, H., Li, Y., Zhang, H., Liu, J., Lu, X., Kwok, R. T. K., Lam, J. W. Y., Ding, D., & Tang, B. Z. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.0c07193 · Cited by 277
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Ma, D., Bian, H., Gu, M., Wang, L., Chen, X., & Peng, X. (2024) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2024.215677 · Cited by 124
Novel small-molecule fluorophores for in vivo NIR-IIa and NIR-IIb imaging
Li, Q., Ding, Q., Li, Y., Zeng, X., Liu, Y., Lu, S., Zhou, H., Wang, X., Wu, J., Meng, X., et al. (2020) · Chemical Communications · doi:10.1039/c9cc09865h · Cited by 90
Metadata
- Authors
- Tang, Y., Pei, F., Lu, X., Fan, Q., & Huang, W.
- Venue
- Advanced Optical Materials
- Publisher
- Wiley
- Published
- 2019-08-12
- Volume
- 7
- Issue
- 21
- ISSN
- 2195-1071 (ISSN-L)
- OpenAlex
- W2966879827
- Cited by
- 165
- References
- 15
- FWCI
- 7.92
- Type
- journal article
- Language
- en
- Open access
- closed
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