Resting-state amplitude of low-frequency fluctuation is associated with suicidal ideation
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BACKGROUND: Identifying brain activity patterns that are associated with suicidal ideation (SI) may help to elucidate its pathogenesis and etiology. Suicide poses a significant public health problem, and SI is a risk factor for suicidal behavior. METHODS: Forty-one unmedicated adult participants in a major depressive episode (MDE), 26 with SI on the Beck Scale for Suicidal Ideation and 15 without SI, underwent resting-state functional magnetic resonance imaging scanning. Twenty-one healthy volunteers (HVs) were scanned for secondary analyses. Whole brain analysis of both amplitude of low-frequency fluctuations (ALFFs) and fractional ALFF was performed in MDE subjects to identify regions where activity was associated with SI. RESULTS: Subjects with SI had greater ALFF than those without SI in two clusters: one in the right hippocampus and one in the thalamus and caudate, bilaterally. Multi-voxel pattern analysis distinguished between those with and without SI. Post hoc analysis of the mean ALFF in the hippocampus cluster found it to be associated with a delayed recall on the Buschke memory task. Mean ALFF from the significant clusters was not associated with depression severity and did not differ between MDE and HV groups. DISCUSSION: These results indicate that SI is associated with altered resting-state brain activity. The pattern of elevated activity in the hippocampus may be related to how memories are processed.
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Resting-state studies of SI in adults diagnosed with MDD have found network changes in the hippocampus, thalamus, caudate, and anterior insula associated with SI scores.
“For example, resting-state studies of SI in adults diagnosed with MDD have found network changes in the hippocampus, thalamus, caudate (66), and anterior insula (72) associated with SI scores.”
From New methods for assessing rapid changes in suicide risk (2021) · cites this paper as [66]
These studies have mostly assessed suicide risk in larger clinical samples of participants diagnosed with mood disorders and other psychiatric conditions with which suicide is a comorbid phenotype, but rarely have they investigated suicide transdiagnostically.
“Finally, these studies have mostly assessed suicide risk in larger clinical samples of participants diagnosed with mood disorders (64–75) and other psychiatric conditions (76–79) with which suicide is a comorbid phenotype, but rarely have they investigated suicide transdiagnostically.”
From New methods for assessing rapid changes in suicide risk (2021) · cites this paper as [66]
Suicidal ideation relates to greater rs-fMRI activity in the vmPFC and greater resting functional connectivity between the OFC and amygdala and between the posterior cingulate cortex and middle temporal gyrus.
“Suicidal ideation relates to greater rs-fMRI activity in the vmPFC (88) and greater resting functional connectivity between the OFC and amygdala (89) and between the posterior cingulate cortex and middle temporal gyrus (90), perhaps related to negative self-reflection or rumination (91).”
From A brain-centric model of suicidal behavior (2020) · cites this paper as [88]
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Scikit-learn: Machine Learning in Python
Pedregosa, F., Varoquaux, G., Gramfort, A., Michel, V., Thirion, B., Grisel, O., Blondel, M., Müller, A., Nothman, J., Louppe, G., et al. (2012) · arXiv · doi:10.48550/arxiv.1201.0490 · Cited by 71,016 · see citing works
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817 · cited 2× · see citing works
“…Clinical Interview (SCID) for DSM‐IV (First, Spitzer, Gibbon, & Williams, 1995); (c) Hamilton Depression Rating Scale‐17 item score ≥16 (HAMD; M. Hamilton, 1960); and (d) if on current antidepressant medications, reported lack of significant benefit and considered to be likely to tolerate…”
BackgroundMethodAn overview of statistical learning theory
Vapnik, V. N. (1999) · IEEE Transactions on Neural Networks · doi:10.1109/72.788640 · Cited by 6,305 · see citing works
The measurement of pessimism: the hopelessness scale
Beck, A. T., Weissman, A., Lester, D., & Trexler, L. (1974) · Journal of Consulting and Clinical Psychology · doi:10.1037/h0037562 · Cited by 5,494 · see citing works
SMITH, S., & NICHOLS, T. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2008.03.061 · Cited by 5,250 · see citing works
Cognitive Therapy of Depression
HOLLON, S. D., & BECK, A. T. (1979) · Cognitive-Behavioral Interventions · doi:10.1016/b978-0-12-404480-7.50012-5 · Cited by 4,685 · see citing works
Permutation inference for the general linear model
Winkler, A. M., Ridgway, G. R., Webster, M. A., Smith, S. M., & Nichols, T. E. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.01.060 · Cited by 3,563 · see citing works
Assessment of suicidal intention: The Scale for Suicide Ideation.
Beck, A. T., Kovacs, M., & Weissman, A. (1979) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.47.2.343 · Cited by 3,419 · see citing works
World health statistics 2016 : monitoring health for the SDGs, sustainable development goals
de la Salud, O. M. (2016) · Virtual Defense Library (Ministerio de Defensa) · Cited by 3,358 · see citing works
Suicide Prevention Strategies: A Systematic Review
Mann, J. J., Apter, A., Bertolote, J., Beautrais, A., Currier, D., Haas, A., Hegerl, U., Lonnqvist, J., Malone, K., Marusic, A., et al. (2005) · JAMA · doi:10.1001/jama.294.16.2064 · Cited by 2,852 · see citing works
Self-citationCross-national prevalence and risk factors for suicidal ideation, plans and attempts
Nock, M. K., Borges, G., Bromet, E. J., Alonso, J., Angermeyer, M., Beautrais, A., Bruffaerts, R., Chiu, W. T., de Girolamo, G., Gluzman, S., et al. (2008) · British Journal of Psychiatry · doi:10.1192/bjp.bp.107.040113 · Cited by 2,654 · see citing works
Prevalence of and Risk Factors for Lifetime Suicide Attempts in the National Comorbidity Survey
Kessler, R. C., Borges, G., & Walters, E. E. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.7.617 · Cited by 2,514 · see citing works
Psychological autopsy studies of suicide: a systematic review.
CAVANAGH, J. T. O., CARSON, A. J., SHARPE, M., & LAWRIE, S. M. (2003) · Psychological Medicine · doi:10.1017/s0033291702006943 · Cited by 2,207 · see citing works
Cognitive-behavioral treatment of chronically parasuicidal borderline patients
Linehan, M. M. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810360024003 · Cited by 2,203 · see citing works
Dalgleish, T. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1432 · Cited by 1,849 · see citing works
Social cognition and the brain: A meta-analysis
Van Overwalle, F. (2009) · Human Brain Mapping · doi:10.1002/hbm.20547 · Cited by 1,792 · see citing works
Toward a clinical model of suicidal behavior in psychiatric patients
Mann, J. J., Waternaux, C., Haas, G. L., & Malone, K. M. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.2.181 · Cited by 1,791 · see citing works
Self-citationSuicide prevention strategies revisited: 10-year systematic review
Zalsman, G., Hawton, K., Wasserman, D., van Heeringen, K., Arensman, E., Sarchiapone, M., Carli, V., Höschl, C., Barzilay, R., Balazs, J., et al. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(16)30030-x · Cited by 1,765 · see citing works
The oscillating brain: Complex and reliable
Zuo, X., Martino, A. D., Kelly, C. A. M., Shehzad, Z. E., Gee, D. G., Klein, D. F., Castellanos, F. X., Biswal, B. B., & Milham, M. P. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.09.037 · Cited by 1,460 · see citing works
Kessler, R. C. (2005) · JAMA · doi:10.1001/jama.293.20.2487 · Cited by 1,071 · see citing works
Cognitive Therapy for the Prevention of Suicide Attempts: A Randomized Controlled Trial
Brown, G. K., Ten Have, T., Henriques, G. R., Xie, S. X., Hollander, J. E., & Beck, A. T. (2005) · JAMA · doi:10.1001/jama.294.5.563 · Cited by 1,045 · see citing works
Hiser, J., & Koenigs, M. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.10.030 · Cited by 972 · see citing works
Depressive rumination, the default-mode network, and the dark matter of clinical neuroscience
Hamilton, J. P., Farmer, M., Fogelman, P., & Gotlib, I. H. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.02.020 · Cited by 952 · see citing works
Thalamus plays a central role in ongoing cortical functioning
Sherman, S. M. (2016) · Nature Neuroscience · doi:10.1038/nn.4269 · Cited by 809 · see citing works
Stone, D. M., Simon, T. R., Fowler, K. A., Kegler, S. R., Yuan, K., Holland, K. M., Ivey-Stephenson, A. Z., & Crosby, A. E. (2018) · MMWR. Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6722a1 · Cited by 634 · see citing works
Oquendo, M. A., Galfalvy, H., Russo, S., Ellis, S. P., Grunebaum, M. F., Burke, A., & Mann, J. J. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.8.1433 · Cited by 605 · see citing works
Self-citationOn the nature and pattern of neurocognitive function in major depressive disorder.
Zakzanis, K. K., Leach, L., & Kaplan, E. (1998) · PubMed · Cited by 406 · see citing works
FAWCETT, J. A., Scheftner, W. A., Clark, D., Hedeker, D., Gibbons, R. D., & Coryell, W. H. (1987) · American Journal of Psychiatry · doi:10.1176/ajp.144.1.35 · Cited by 384 · see citing works
Neuropsychological dysfunction in depressed suicide attempters
Keilp, J. G., Sackeim, H. A., Brodsky, B. S., Oquendo, M. A., Malone, K. M., & Mann, J. J. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.5.735 · Cited by 372 · see citing works
Self-citationLindquist, M. A., Xu, Y., Nebel, M. B., & Caffo, B. S. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.06.052 · Cited by 369 · see citing works
Keilp, J. G., Gorlyn, M., Russell, M., Oquendo, M. A., Burke, A. K., Harkavy-Friedman, J., & Mann, J. J. (2013) · Psychological Medicine · doi:10.1017/s0033291712001419 · Cited by 350 · see citing works
Self-citationMiranda, R., & Nolen-Hoeksema, S. (2007) · Behaviour Research and Therapy · doi:10.1016/j.brat.2007.07.015 · Cited by 344 · see citing works
Richard-Devantoy, S., Berlim, M. T., & Jollant, F. (2014) · Psychological Medicine · doi:10.1017/s0033291713002304 · Cited by 324 · see citing works
Resting-State Brain Activity in Schizophrenia and Major Depression: A Quantitative Meta-Analysis
Kühn, S., & Gallinat, J. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr151 · Cited by 287 · see citing works
Craddock, R. C., Sikka, S., Brian, C., Khanuja, R., Ghosh, S., Chaogan, Y., Li, Q., Daniel, L., Joshua, V., Randal, B., et al. (2013) · Frontiers in Neuroinformatics · doi:10.3389/conf.fninf.2013.09.00042 · Cited by 286 · see citing works
Smith, J. M., Alloy, L. B., & Abramson, L. Y. (2006) · Suicide and Life-Threatening Behavior · doi:10.1521/suli.2006.36.4.443 · Cited by 258 · see citing works
Relation Between Structural and Functional Connectivity in Major Depressive Disorder
de Kwaasteniet, B., Ruhe, E., Caan, M., Rive, M., Olabarriaga, S., Groefsema, M., Heesink, L., van Wingen, G., & Denys, D. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.12.024 · Cited by 229 · see citing works
Memory Function and the Hippocampus
Opitz, B. (2014) · Monographs in clinical neuroscience/Frontiers of neurology and neuroscience/Monographs in neural sciences · doi:10.1159/000356422 · Cited by 209 · see citing works
Li, J., Duan, X., Cui, Q., Chen, H., & Liao, W. (2019) · Psychological Medicine · doi:10.1017/s0033291718001502 · Cited by 208 · see citing works
Olié, E., Guillaume, S., Jaussent, I., Courtet, P., & Jollant, F. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.03.013 · Cited by 174 · see citing works
Further Reflections on Suicide and Psychache
Shneidman, E. S. (1998) · Suicide and Life-Threatening Behavior · doi:10.1111/j.1943-278x.1998.tb00854.x · Cited by 164 · see citing works
Combining dependent P- values with an empirical adaptation of Brown’s method
Poole, W., Gibbs, D. L., Ilya Shmulevich, C., Bernard, B. M., & Knijnenburg, T. (2016) · Bioinformatics · doi:10.1093/bioinformatics/btw438 · Cited by 158 · see citing works
Mundt, J. C., Greist, J. H., Jefferson, J. W., Federico, M., Mann, J. J., & Posner, K. (2013) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.13m08398 · Cited by 152 · see citing works
Self-citationPerspectives on suicidology. Further reflections on suicide and psychache.
Shneidman, E. S. (1998) · PubMed · Cited by 145 · see citing works
Du, L., Zeng, J., Liu, H., Tang, D., Meng, H., Li, Y., & Fu, Y. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.02.027 · Cited by 129 · see citing works
Self‐Esteem and Suicide Ideation in Psychiatric Outpatients
Bhar, S. S., Ghahramanlou‐Holloway, M., Brown, G. K., & Beck, A. T. (2008) · Suicide and Life-Threatening Behavior · doi:10.1521/suli.2008.38.5.511 · Cited by 120 · see citing works
Network basis of suicidal ideation in depressed adolescents
Ordaz, S. J., Goyer, M. S., Ho, T. C., Singh, M. K., & Gotlib, I. H. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.09.021 · Cited by 111 · see citing works
Kang, S.-G., Na, K.-S., Choi, J.-W., Kim, J.-H., Son, Y.-D., & Lee, Y. J. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.04.029 · Cited by 110 · see citing works
Sundermann, B., Beverborg, M. O. L., & Pfleiderer, B. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00692 · Cited by 109 · see citing works
Kim, K., Kim, S.-W., Myung, W., Han, C. E., Fava, M., Mischoulon, D., Papakostas, G. I., Seo, S. W., Cho, H., Seong, J.-K., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-15926-0 · Cited by 107 · see citing works
Neuropsychological deficits in past suicide attempters with varying levels of depression severity
Keilp, J. G., Beers, S. R., Burke, A. K., Melhem, N. M., Oquendo, M. A., Brent, D. A., & Mann, J. J. (2014) · Psychological Medicine · doi:10.1017/s0033291714000786 · Cited by 88 · see citing works
Self-citationvan Spijker, B. A. J., van Straten, A., & Kerkhof, A. J. F. M. (2010) · Trials · doi:10.1186/1745-6215-11-25 · Cited by 85 · see citing works
Cox, B. J., Enns, M. W., & Clara, I. P. (2004) · Suicide and Life-Threatening Behavior · doi:10.1521/suli.34.3.209.42781 · Cited by 82 · see citing works
Test-retest reliability of dynamic functional connectivity in resting state fMRI
Zhang, C., Baum, S. A., Adduru, V. R., Biswal, B. B., & Michael, A. M. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.08.021 · Cited by 82 · see citing works
Chase, H. W., Segreti, A. M., Keller, T. A., Cherkassky, V. L., Just, M. A., Pan, L. A., & Brent, D. A. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.01.013 · Cited by 78 · see citing works
Cognitive control deficits differentiate adolescent suicide ideators from attempters
Stewart, J. G., Glenn, C. R., Esposito, E. C., Cha, C. B., Nock, M. K., & Auerbach, R. P. (2017) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.16m10647 · Cited by 67 · see citing works
Mental health care for adults with suicide ideation
Brook, R., Klap, R., Liao, D., & Wells, K. B. (2006) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2006.01.001 · Cited by 43 · see citing works
Economía campesina en la vereda San Francisco, municipio de Toca, Boyacá
Mujica Olejua, C. A. (2018) · Intellectum (Universidad de La Sabana) · doi:10.1016/s2215 · Cited by 6 · see citing works
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- Oquendo MA, Halberstam B, & Mann JJ (2003). Risk factors for suicidal behavior: utility and limitations of research instruments. In First MB (Ed.), Standardized evaluation in clinical practice (1st ed., pp. 103– 130). Washington DC: American Psychiatric Publishing.
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Wagner, G., Li, M., Sacchet, M. D., Richard‐Devantoy, S., Turecki, G., Bär, K., Gotlib, I. H., Walter, M., & Jollant, F. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01232-x · Cited by 58 · see citing works
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Chahla, M. N. A., Khalil, M. I. M., Comai, S., Brundin, L., Erhardt, S., & Guillemin, G. J. (2023) · Brain Sciences · doi:10.3390/brainsci13030505 · Cited by 47 · see citing works
Li, X., Yu, R., Huang, Q., Chen, X.-L., Ai, M., Zhou, Y., Dai, L., Qin, X., & Kuang, L. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.762343 · Cited by 45 · see citing works
Chen, Q., Bi, Y., Zhao, X., Lai, Y., Yan, W., Xie, L., Gao, T., Xie, S., Zeng, T., Li, J., et al. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.03.079 · Cited by 43 · see citing works
Chen, C.-F., Chen, W.-N., & Zhang, B. (2021) · Brain Imaging and Behavior · doi:10.1007/s11682-021-00503-x · Cited by 35 · see citing works
Zhu, R., Tian, S., Wang, H., Jiang, H., Wang, X., Shao, J., Wang, Q., Yan, R., Tao, S., Liu, H., et al. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.597770 · Cited by 30 · see citing works
Tian, S., Zhu, R., Chattun, M. R., Wang, H., Chen, Z., Zhang, S., Shao, J., Wang, X., Yao, Z., & Lü, Q. (2021) · Brain Imaging and Behavior · doi:10.1007/s11682-020-00448-7 · Cited by 28 · see citing works
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Chai, X., Zhang, R., Xue, C., Li, Z., Wang, X., Huang, Q., Xiao, C., & Xie, S. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.587803 · Cited by 22 · see citing works
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Zhao, Y., Wang, L., Edmiston, E. K., Womer, F. Y., Jiang, X., Wu, F., Kong, L., Zhou, Y., Wang, F., Tang, Y., et al. (2020) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2020.111229 · Cited by 21 · see citing works
Liu, Y., Gao, Y. H., Li, M., Qin, W., Xie, Y., Zhao, G., Wang, Y., Yang, C., Zhang, B., Jing, Y., et al. (2023) · Neuroscience Letters · doi:10.1016/j.neulet.2023.137196 · Cited by 19 · see citing works
Lin, S., Chen, Z., Zhao, Y., & Gong, Q. (2025) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.240112 · Cited by 16 · see citing works
Zhuo, C., Zhou, C., Lin, X., Tian, H., Wang, L., Chen, C., Ji, F., Xu, Y. J., & Jian, D. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109738 · Cited by 16 · see citing works
Zhong, S., Chen, P., Lai, S., Zhang, Y., Chen, G., He, J., Pan, Y., Tang, G., Wang, Y., & Jia, Y. (2023) · Neuroendocrinology · doi:10.1159/000534033 · Cited by 16 · see citing works
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He, C., Wang, Y., Bai, H., Li, R., & Fang, X. (2022) · Computational and Mathematical Methods in Medicine · doi:10.1155/2022/3741677 · Cited by 3 · see citing works
Zhang, M., Liu, Z., Zhong, M., Wang, Y. Q., Wang, F., Yang, J., & Yang, J. (2025) · Psychological Medicine · doi:10.1017/s0033291725102791 · Cited by 3 · see citing works
Palombelli, G., Zecca, V., Boffa, M., Carola, C., Singh, T., Risio, L. D., Pettorruso, M., Zoratto, F., & Canese, R. (2026) · Scientific Reports · doi:10.1038/s41598-026-45121-z · Cited by 2 · see citing works
Zu, M., Fu, L., Hu, M., Cao, X., Wang, L., Zhang, J., Deng, Z., Qiu, B., & Wang, Y. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.847366 · Cited by 2 · see citing works
An, Z., Tang, K., Ren, B., Tao, Q., Tong, C., Zhang, X., Zhao, L., Liu, J., & Feng, Y. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111562 · Cited by 1 · see citing works
Li, Q., Lü, Y., Sun, J., Huang, G., Gong, Y., Zhang, B., Chen, Z., Zhang, X., Huang, Y. F., Zeng, X., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2409325/v1 · Cited by 1 · see citing works
Das, S. C., Schulmann, A., Callor, W. B., Jerominski, L., Panicker, M. M., Christensen, E. D., Bunney, W. E., Williams, M. E., Coon, H. H., & Vawter, M. P. (2023) · medRxiv · doi:10.1101/2023.01.28.23285121
Olié, É., Clain, G., Malestroit, M., Fiedos, D., Cognasse, F., Deverdun, J., Bars, E. L., & Courtet, P. (2023) · Research Square · doi:10.21203/rs.3.rs-2669073/v1
Identification of key genes for glioblastoma microenvironment
Xu, Z. (2023) · Theoretical and Natural Science · doi:10.54254/2753-8818/8/20240355
Li, J., Chen, X., Tao, L., Wei, X., & Tao, J. (2025) · Medicine · doi:10.1097/md.0000000000043860
Zhang, M., Zhong, M., Liu, Z., Wang, Y., Wang, F., Yang, J., Tan, L., & Yang, J. (2025) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2025.104709
Liu, Y., Deng, J., Zhou, J., Sun, Y., Zhou, Y., Peng, X., Gong, K., Liu, K., Lei, W., & Chen, J. (2025) · Behavioural Brain Research · doi:10.1016/j.bbr.2025.115944
Bergman, E., Miller, J. M., Sublette, M. E., Burke, A. K., Mann, J. J., & Lan, M. J. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.122005
Self-citationEllingham, J., Turner, H. M., Tatham, M., & Waller, G. (2026) · International Journal of Eating Disorders · doi:10.1002/eat.70222
Zheng, Y., Han, L., Zou, M., Wang, J., Yu, M., Cui, N., Lu, X., Lei, W., & Chen, G. (2026) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2026.111977
- Authors
- Lan, M. J., Rizk, M. M., Pantazatos, S. P., Rubin‐Falcone, H., Miller, J. M., Sublette, M. E., Oquendo, M. A., Keilp, J. G., & Mann, J. J.
- Affiliations
- New York State Psychiatric Institute (US)
- Department of PsychiatryPerelman School of MedicineUniversity of PennsylvaniaPhiladelphia Pennsylvania
- Corresponding author
- Lan, Martin J.
- ORCID
- Venue
- Depression and Anxiety
- Publisher
- Wiley
- Published
- 2019-03-21
- Volume
- 36
- Issue
- 5
- Pages
- 433-441
- ISSN
- 1091-4269 (ISSN-L)
- 1520-6394
- PMC
- PMC6488362
- OpenAlex
- W2924751981
- Cited by
- 48
- References
- 57
- Citations by year
- 2026: 4 · 2025: 10 · 2024: 2 · 2023: 8 · 2022: 9 · 2021: 8 · 2020: 5 · 2019: 2
- FWCI
- 3.49
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Depression and Anxiety (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (K23MH10568, K08MH079033, K08MH085061, K01MH108721)
- Institut National de la Santé et de la Recherche Médicale (K08MH085061)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- suicidal ideation, amplitude of low-frequency fluctuation, resting-state brain activity, major depressive episode, hippocampus, thalamus, caudate nucleus, memory retrieval, multi-voxel pattern analysis, suicide risk
- MeSH terms
- Adult, Brain Mapping, Caudate Nucleus, Major Depressive Disorder, Female, Hippocampus, Humans, Magnetic Resonance Imaging, Male, Thalamus, Suicidal Ideation
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