Per- and Polyfluoroalkyl Substances (PFAS) in Surface Water Near US Air Force Bases: Prioritizing Individual Chemicals and Mixtures for Toxicity Testing and Risk Assessment
Abstract
Per- and polyfluoroalkyl substances (PFAS) are a large class of persistent chemicals used for decades in industrial and commercial applications. A key challenge with regard to estimating potential risk to ecological (and human) receptors associated with PFAS exposure lies in the fact that there are many different PFAS compounds and several to many can co-occur in any given environmental sample. We applied a data science approach to characterize and prioritize PFAS and PFAS mixtures from a large dataset of PFAS measurements in surface waters associated with US Air Force Installations with a history of the use of aqueous film-forming foams (AFFFs). Several iterations of stakeholder feedback culminated in a few main points that advanced our understanding of a complex dataset and the larger ecotoxicological problem. First, perfluorooctane sulfonate (PFOS) was often a dominant PFAS in a given surface water sample, frequently followed by perfluorohexane sulfonate (PFHxS). Second, a 4-chemical mixture generally accounted for >80% of the sum of all routinely reported PFAS in a sample, and the most representative 4-chemical mixture was composed of PFOS, PFHxS, perfluorohexanoic acid (PFHxA), and perfluorooctanoic acid (PFOA). We suggest that these results demonstrate the utility of formalized data science analysis and assessment frameworks to address complex ecotoxicological problems. Specifically, our example dataset results can be used to provide perspective on toxicity testing, eco…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Runoff and groundwater contamination from historical AFFF use raises concern for environmental contamination.
“Runoff and groundwater contamination from historical AFFF use raises concern for environmental contamination (East, Anderson & Salice, 2021).”
From Perfluoroalkyl acids in sediment and water surrounding historical fire training areas at Barksdale Air Force Base (2022) · cites this paper as East, Anderson & Salice, 2021
Our PFAS observations in terms of quantities and mixtures are consistent with those reported in East, Anderson & Salice (2021).
“Further, our PFAS observations in terms of quantities and mixtures is consistent with those reported in East, Anderson & Salice (2021).”
From Perfluoroalkyl acids in sediment and water surrounding historical fire training areas at Barksdale Air Force Base (2022) · cites this paper as East, Anderson & Salice, 2021
The observed sulfonate signature, especially high concentrations of PFHxS and PFOS, can be characteristic of historic AFFF use.
“This type of observed sulfonate signature, especially high concentrations of PFHxS and PFOS, can be characteristic of historic AFFF use.”
Cites
R: A Language and Environment for Statistical Computing
R Core Team (2000) · doi:10.32614/r.manuals · Cited by 355,706 · see citing works
Wickham, H., Averick, M., Bryan, J., Chang, W., McGowan, L., François, R., Grolemund, G., Hayes, A., Henry, L., Hester, J., et al. (2019) · Journal of Open Source Software · doi:10.21105/joss.01686 · Cited by 22,138 · see citing works
US Environmental Protection Agency
Liu, X. (1998) · Choice Reviews Online · doi:10.5860/choice.35-4455 · Cited by 5,887 · see citing works
Global Distribution of Perfluorooctane Sulfonate in Wildlife
Giesy, J. P., & Kannan, K. (2001) · Environmental Science & Technology · doi:10.1021/es001834k · Cited by 2,750 · see citing works
Hu, X. C., Andrews, D. Q., Lindstrom, A. B., Bruton, T. A., Schaider, L. A., Grandjean, P., Lohmann, R., Carignan, C. C., Blum, A., Balan, S. A., et al. (2016) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.6b00260 · Cited by 1,333 · see citing works
Barzen-Hanson, K. A., Roberts, S. C., Choyke, S., Oetjen, K., McAlees, A., Riddell, N., McCrindle, R., Ferguson, P. L., Higgins, C. P., & Field, J. A. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.6b05843 · Cited by 873 · see citing works
Perfluorinated Surfactants and the Environmental Implications of Their Use in Fire-Fighting Foams
Moody, C. A., & Field, J. A. (2000) · Environmental Science & Technology · doi:10.1021/es991359u · Cited by 707 · see citing works
Identification of Novel Fluorochemicals in Aqueous Film-Forming Foams Used by the US Military
Place, B. J., & Field, J. A. (2012) · Environmental Science & Technology · doi:10.1021/es301465n · Cited by 543 · see citing works
Ankley, G. T., Cureton, P., Hoke, R. A., Houde, M., Kumar, A., Kurias, J., Lanno, R., McCarthy, C., Newsted, J., Salice, C. J., et al. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4869 · Cited by 454 · cited 5× · see citing works
“Although regulatory developments for PFAS are largely driven by public health concerns, many ecosystems and ecological receptors are also exposed (McCarthy et al. 2017; Ankley et al. 2020, this issue).”
BackgroundInfluentialSelf-citationAnderson, R. H., Long, G. C., Porter, R. C., & Anderson, J. K. (2016) · Chemosphere · doi:10.1016/j.chemosphere.2016.01.014 · Cited by 394 · see citing works
Self-citationMoody, C. A., Hebert, G. N., Strauss, S. H., & Field, J. A. (2003) · Journal of Environmental Monitoring · doi:10.1039/b212497a · Cited by 388 · see citing works
Houtz, E. F., Sutton, R., Park, J.-S., & Sedlak, M. (2016) · Water Research · doi:10.1016/j.watres.2016.02.055 · Cited by 374 · see citing works
Ahrens, L., Norström, K., Viktor, T., Cousins, A. P., & Josefsson, S. (2015) · Chemosphere · doi:10.1016/j.chemosphere.2014.03.136 · Cited by 288 · see citing works
Filipovic, M., Woldegiorgis, A., Norström, K., Bibi, M., Lindberg, M., & Österås, A.-H. (2015) · Chemosphere · doi:10.1016/j.chemosphere.2014.09.005 · Cited by 284 · see citing works
Ankley, G. T., Kuehl, D. W., Kahl, M. D., Jensen, K. M., Linnum, A. L., Leino, R. L., & Villeneuve, D. A. (2005) · Environmental Toxicology and Chemistry · doi:10.1897/04-634r.1 · Cited by 200 · see citing works
Dauchy, X., Boiteux, V., Bach, C., Rosin, C., & Munoz, J.-F. (2017) · Chemosphere · doi:10.1016/j.chemosphere.2017.05.056 · Cited by 198 · see citing works
de Solla, S. R., De Silva, A. O., & Letcher, R. J. (2012) · Environment International · doi:10.1016/j.envint.2011.09.011 · Cited by 198 · see citing works
Baduel, C., Mueller, J. F., Rotander, A., Corfield, J., & Gomez-Ramos, M.-J. (2017) · Chemosphere · doi:10.1016/j.chemosphere.2017.06.096 · Cited by 192 · see citing works
Vogs, C., Johanson, G., Näslund, M., Wulff, S., Sjödin, M. O. D., Hellstrandh, M., Lindberg, J., & Wincent, E. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.8b07188 · Cited by 127 · see citing works
Combined Effects of PFOS and PFOA on Zebrafish (Danio rerio) Embryos
Ding, G., Zhang, J., Chen, Y., Wang, L., Wang, M., Xiong, D., & Sun, Y. (2013) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-012-9864-2 · Cited by 114 · see citing works
Ecological Considerations of Per- and Polyfluoroalkyl Substances (PFAS)
McCarthy, C., Kappleman, W. B., & DiGuiseppi, W. H. (2017) · Current Pollution Reports · doi:10.1007/s40726-017-0070-8 · Cited by 108 · see citing works
Acute and chronic toxicity of short chained perfluoroalkyl substances to Daphnia magna
Barmentlo, S. H., Stel, J. M., van Doorn, M., Eschauzier, C., de Voogt, P., & Kraak, M. H. S. (2014) · Environmental Pollution · doi:10.1016/j.envpol.2014.12.025 · Cited by 87 · see citing works
Custer, C. M., Custer, T. W., Dummer, P. M., Etterson, M. A., Thogmartin, W. E., Wu, Q., Kannan, K., Trowbridge, A. G., & McKann, P. C. (2013) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-013-9934-0 · Cited by 86 · see citing works
Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate
Hoke, R. A., Ferrell, B. D., Ryan, T., Sloman, T. L., Green, J. W., Nabb, D. L., Mingoia, R., Buck, R. C., & Korzeniowski, S. H. (2015) · Chemosphere · doi:10.1016/j.chemosphere.2015.01.033 · Cited by 82 · see citing works
Yang, H., Zhao, Y., Tang, Y., Gong, H.-Q., Guo, F., Sun, W., Liu, S., Tan, H., & Chen, F. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.02.418 · Cited by 76 · see citing works
Caron-Beaudoin, É., Ayotte, P., Sidi, E. A. L., McHugh, N. G.-L., & Lemire, M. (2019) · Environment International · doi:10.1016/j.envint.2019.04.029 · Cited by 75 · see citing works
Flynn, R. W., Chislock, M. F., Gannon, M. E., Bauer, S. J., Tornabene, B. J., Hoverman, J. T., & Sepúlveda, M. S. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.124350 · Cited by 70 · see citing works
Wolf, C. J., Rider, C. V., Lau, C., & Abbott, B. D. (2014) · Toxicology · doi:10.1016/j.tox.2013.12.002 · Cited by 69 · see citing works
Groffen, T., Lasters, R., López‐Antia, A., Prinsen, E., Bervoets, L., & Eens, M. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.10.273 · Cited by 64 · see citing works
Lanza, H. A., Cochran, R. S., Mudge, J. F., Olson, A. D., Blackwell, B. R., Maul, J. D., Salice, C. J., & Anderson, T. A. (2016) · Environmental Toxicology and Chemistry · doi:10.1002/etc.3726 · Cited by 62 · see citing works
Self-citationAnderson, J. K., Luz, A. L., Goodrum, P., & Durda, J. (2019) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2019.01.020 · Cited by 56 · see citing works
Annunziato, K. M., Jantzen, C. E., Gronske, M. C., & Cooper, K. R. (2019) · Aquatic Toxicology · doi:10.1016/j.aquatox.2019.01.009 · Cited by 52 · see citing works
Larson, E. S., Conder, J. M., & Arblaster, J. A. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.03.004 · Cited by 38 · see citing works
Salice, C. J., Anderson, T. A., Anderson, R. H., & Olson, A. D. (2018) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4162 · Cited by 33 · see citing works
Self-citationBrown, S. R., Flynn, R. W., & Hoverman, J. T. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4678 · Cited by 30 · see citing works
Suski, J. G., Salice, C. J., Chanov, M. K., Ayers, J., Rewerts, J. N., & Field, J. A. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4936 · Cited by 28 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Ankley, G. T., Cureton, P., Hoke, R. A., Houde, M., Kumar, A., Kurias, J., Lanno, R., McCarthy, C., Newsted, J., Salice, C. J., et al. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4869 · Cited by 454 · see citing works
Self-citationThe occurrence, distribution, and risks of PFAS at AFFF-impacted sites in Finland
Reinikainen, J., Perkola, N., Äystö, L., & Sorvari, J. (2022) · Science of The Total Environment · doi:10.1016/j.scitotenv.2022.154237 · Cited by 142 · see citing works
Comprehensive analysis of PFAS presence from environment to plate
Dimitrakopoulou, M., Karvounis, M., Marinos, G., Theodorakopoulou, Z., Aloizou, E., Petsangourakis, G., Papakonstantinou, M., & Stoitsis, G. (2024) · npj Science of Food · doi:10.1038/s41538-024-00319-1 · Cited by 121 · see citing works
Li, X., Fatowe, M., Cui, D., & Quinete, N. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.150393 · Cited by 88 · see citing works
Brown, A. S., Yun, X., McKenzie, E. R., Heron, C. G., Field, J. A., & Salice, C. J. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.163149 · Cited by 63 · see citing works
Self-citationPerformance testing of mesh anodes for in situ electrochemical oxidation of PFAS
Fenti, A., Jin, Y., Rhoades, A. J. H., Dooley, G., Iovino, P., Salvestrini, S., Musmarra, D., Mahendra, S., Peaslee, G. F., & Blotevogel, J. (2021) · Chemical Engineering Journal Advances · doi:10.1016/j.ceja.2021.100205 · Cited by 57 · see citing works
Considerations for toxicity experiments and risk assessments with PFAS mixtures
McCarthy, C. J., Roark, S. A., & Middleton, E. T. (2021) · Integrated Environmental Assessment and Management · doi:10.1002/ieam.4415 · Cited by 46 · see citing works
Flynn, R. W., Hoover, G., Iacchetta, M., Guffey, S. C., de Perre, C., Huerta, B., Li, W., Hoverman, J. T., Lee, L., & Sepúlveda, M. S. (2022) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5319 · Cited by 42 · see citing works
Lorah, M. M., He, K. F., Blaney, L. M., Akob, D. M., Harris, C., Tokranov, A. K., Hopkins, Z. R., & Shedd, B. P. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.172996 · Cited by 40 · see citing works
Zhao, Z., Li, J., Zhang, X., Wang, L., Wang, J., & Lin, T. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-20755-4 · Cited by 41 · see citing works
McCarthy, C., Roark, S. A., Wright, D., O’Neal, K., Muckey, B. D., Stanaway, M., Rewerts, J. N., Field, J. A., Anderson, T. A., & Salice, C. J. (2021) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5066 · Cited by 37 · see citing works
Self-citationGharehveran, M. M., Walus, A. M., Anderson, T. A., Subbiah, S., Guelfo, J., Frigon, M., Longwell, A., & Suski, J. G. (2022) · Journal of Environmental Chemical Engineering · doi:10.1016/j.jece.2022.108953 · Cited by 33 · see citing works
Application of soil amendments for reducing PFAS leachability and bioavailability
Juhasz, A. L., Kastury, F., Herde, C., & Tang, W. (2022) · Environmental Pollution · doi:10.1016/j.envpol.2022.119498 · Cited by 31 · see citing works
Strategic resources for assessing PFAS ecological risks at AFFF sites
Conder, J., Zodrow, J. M., Arblaster, J. A., Kelly, B. C., Gobas, F. A. P. C., Suski, J. G., Osborn, E., Frenchmeyer, M., Divine, C. E., & Leeson, A. (2021) · Integrated Environmental Assessment and Management · doi:10.1002/ieam.4405 · Cited by 29 · see citing works
Surface Science View of Perfluoroalkyl Acids (PFAAs) in the Environment
Brahana, P. J., Patel, R., & Bharti, B. (2024) · ACS Environmental Au · doi:10.1021/acsenvironau.3c00079 · Cited by 28 · see citing works
Suski, J. G., Salice, C. J., Chanov, M. K., Ayers, J., Rewerts, J. N., & Field, J. A. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4936 · Cited by 28 · see citing works
Self-citationNarizzano, A. M., Lent, E. M., Hanson, J. M., East, A., Bohannon, M., & Quinn, M. J. (2022) · Reproductive Toxicology · doi:10.1016/j.reprotox.2022.08.011 · Cited by 27 · see citing works
Self-citationGoukeh, M. N., & Alamdari, N. (2024) · Journal of Environmental Engineering · doi:10.1061/joeedu.eeeng-7478 · Cited by 22 · see citing works
Occurrence of a “forever chemical” in the atmosphere above pristine Amazon Forest
Kourtchev, I., Sebben, B. G., Brill, S., Cybelli, G. G. B., Weber, B., Ferreira, R. R., D’Oliveira, F. A. F., Dias‐Júnior, C. Q., Popoola, O., Williams, J., et al. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.173918 · Cited by 22 · see citing works
Dioxins vs. PFAS: Science and Policy Challenges
George, A. J., & Birnbaum, L. S. (2024) · Environmental Health Perspectives · doi:10.1289/ehp14449 · Cited by 20 · see citing works
Martin, K. V., Hilbert, T. J., Reilly, M. J., Christian, W. J., Hoover, A., Pennell, K. G., Ding, Q., & Haynes, E. N. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-27880-8 · Cited by 21 · see citing works
Kadlec, S. M., Backe, W. J., Erickson, R. J., Hockett, J. R., Howe, S. E., Mundy, I. D., Piasecki, E., Sluka, H., Votava, L. K., & Mount, D. R. (2023) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5784 · Cited by 22 · see citing works
Li, S., Goodrich, J. A., Costello, E. J., Walker, D. I., Cardenas‐Iniguez, C., Chen, J. C., Alderete, T. L., Valvi, D., Rock, S., Eckel, S. P., et al. (2024) · Environmental Research · doi:10.1016/j.envres.2024.120370 · Cited by 20 · see citing works
Bohannon, M., Narizzano, A. M., Guigni, B. A., East, A., & Quinn, M. J. (2023) · Toxicological Sciences · doi:10.1093/toxsci/kfad006 · Cited by 19 · see citing works
Self-citationLech, M. E., Choi, Y. J., Lee, L., Sepúlveda, M. S., & Hoverman, J. T. (2022) · Environmental Science & Technology · doi:10.1021/acs.est.2c04574 · Cited by 19 · see citing works
Groffen, T., Bervoets, L., & Eens, M. (2022) · Environmental Research · doi:10.1016/j.envres.2022.114644 · Cited by 18 · see citing works
PFAS assessment in fish – Samples from Illinois waters
Sands, M., Zhang, X., Jensen, T., Frano, M. R. L., Lin, M., & Irudayaraj, J. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.172357 · Cited by 17 · see citing works
McDonough, A. M., Bird, A. W., Freeman, L. M., Luciani, M. A., & Todd, A. K. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.117115 · Cited by 15 · see citing works
Hoskins, T. D., Flynn, R. W., Coogan, G. S. M., Catlin, A. C., de Perre, C., Gharehveran, M. M., Choi, Y. J., Lee, L., Hoverman, J. T., & Sepúlveda, M. S. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.3c01118 · Cited by 15 · see citing works
Gust, K. A., Mylroie, J. E., Kimble, A. N., Wilbanks, M. S., Steward, C., Chapman, K., Jensen, K. M., Kennedy, A. R., Krupa, P. M., Waisner, S. A., et al. (2023) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5770 · Cited by 17 · see citing works
Environmental impact of PFAS incineration
Kovacs, J., Higgins, R., Ionesco, N., & Cho, Y. I. (2025) · Waste Management Bulletin · doi:10.1016/j.wmb.2025.100202 · Cited by 14 · see citing works
You, D., Chang, X., Guo, L., Xie, W., Huang, S., Li, X., Chai, H., & Wang, Y. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.134367 · Cited by 14 · see citing works
Woodward, E. E., Senior, L. A., Fleck, J. A., Barber, L. B., Hansen, A. M., & Duris, J. W. (2024) · ACS ES&T Water · doi:10.1021/acsestwater.4c00288 · Cited by 14 · see citing works
Comparative Toxicity of Seven Aqueous Film-Forming Foam to In Vitro Systems and Mus
East, A., Narizzano, A. M., Holden, L. A., Bazar, M. A., Bohannon, M., Pervitsky, D., Adams, V. H., Reinke, E. N., & Quinn, M. J. (2023) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5714 · Cited by 13 · see citing works
Self-citationDennis, N. M., Hossain, F., Subbiah, S., Karnjanapiboonwong, A., Dennis, M. L., McCarthy, C., Jackson, W. A., Crago, J., Salice, C. J., & Anderson, T. A. (2021) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5238 · Cited by 14 · see citing works
Self-citationHoskins, T. D., Allmon, E. B., Flynn, R. W., Lee, L., Choi, Y. J., Hoverman, J. T., & Sepúlveda, M. S. (2022) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5486 · Cited by 13 · see citing works
Patterns in Serum Toxicokinetics in Peromyscus Exposed to Per- and Polyfluoroalkyl Substances
Narizzano, A. M., Bohannon, M., East, A., McDonough, C. A., Choyke, S. J., Higgins, C. P., & Quinn, M. J., Jr. (2021) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5151 · Cited by 13 · see citing works
Self-citationFlynn, K. M., Bush, K., Cavallin, J. E., Hazemi, M., Kasparek, A., Schümann, P., & Villeneuve, D. L. (2025) · Environmental Toxicology and Chemistry · doi:10.1093/etojnl/vgaf022 · Cited by 12 · see citing works
Currie, S. D., Benson, D. B., Xie, Z., Wang, J., & Tang, L. (2025) · Journal of Xenobiotics · doi:10.3390/jox15010024 · Cited by 12 · see citing works
PFAS Destruction in IX Still Bottoms with Plasma Vortex Technology
Higgins, R. J., Kim, H., Houtz, E. F., Newman, P. A., Casey, D., & Cho, Y. I. (2025) · ACS ES&T Water · doi:10.1021/acsestwater.4c00863 · Cited by 12 · see citing works
Physiologically based pharmacokinetic (PBPK) modeling of perfluorohexane sulfonate (PFHxS) in humans
Sweeney, L. M. (2021) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2021.105099 · Cited by 12 · see citing works
Reproductive and immune effects emerge at similar thresholds of PFHxS in deer mice
Narizzano, A. M., Bohannon, M., East, A., Guigni, B. A., & Quinn, M. J. (2023) · Reproductive Toxicology · doi:10.1016/j.reprotox.2023.108421 · Cited by 12 · see citing works
Self-citationLeveraging Multiple Data Streams for Prioritization of Mixtures for Hazard Characterization
Rivera, B. N., Ghetu, C. C., Chang, Y., Truong, L., Tanguay, R. L., Anderson, K. A., & Tilton, S. C. (2022) · Toxics · doi:10.3390/toxics10110651 · Cited by 11 · see citing works
Hayman, N. T., Carilli, J., Liu, Y., Shields, M. R., Hsu, L., & George, R. (2023) · Remediation Journal · doi:10.1002/rem.21747 · Cited by 11 · see citing works
Bushong, A. G., Sepúlveda, M. S., Scherer, M., Valachovic, A. C., Neill, C. M., Horn, S., Choi, Y. J., Lee, L., Baloni, P., & Hoskins, T. (2024) · Toxics · doi:10.3390/toxics12100732 · Cited by 10 · see citing works
Wilkinson, R. S., Lanza, H. A., Olson, A. D., Mudge, J. F., Salice, C. J., & Anderson, T. A. (2022) · PeerJ · doi:10.7717/peerj.13054 · Cited by 10 · see citing works
Self-citationCurrie, S. D., Ji, Y., Huang, Q., Wang, J., & Tang, L. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.125257 · Cited by 10 · see citing works
East, A., Anderson, R. H., Duncan, C. M., & Salice, C. J. (2025) · Environmental Toxicology and Chemistry · doi:10.1093/etojnl/vgaf001 · Cited by 9 · see citing works
Self-citationPFAS surveillance within a highly militarized island: a case study of Okinawa, Japan
Camacho, C. G., Costa, K. A., McMahon, S., Jolly, J., Ravasi, T., Aufmuth, J., & Bowden, J. A. (2024) · Environmental Science Processes & Impacts · doi:10.1039/d4em00508b · Cited by 9 · see citing works
Suski, J. G., Chanov, M. K., Heron, C. G., Field, J. A., & Salice, C. J. (2023) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5692 · Cited by 8 · see citing works
Self-citationDennis, N. M., Hossain, F., Subbiah, S., Karnjanapiboonwong, A., Dennis, M. L., McCarthy, C., Heron, C. G., Jackson, W. A., Crago, J., Field, J. A., et al. (2021) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5135 · Cited by 9 · see citing works
Self-citationEmerging Contaminants in Groundwater: Challenges, Management, and Policy Perspectives
Narimani, R., Murgulet, I., & Murgulet, D. (2025) · Advances in water security · doi:10.1007/978-3-031-71758-1_9 · Cited by 9 · see citing works
Miller, A. J., Kleemann, K., Glüge, J., Lohmann, R., Cousins, I. T., Herzke, D., Miller, M. F., Rensmo, A., Trier, X., Wang, Z., et al. (2026) · Environmental Science & Technology · doi:10.1021/acs.est.5c18001 · Cited by 10 · see citing works
Hayman, N. T., Pandelides, Z., Discar, J., Colvin, M. A., Rosen, G. H., Arblaster, J. A., & Conder, J. (2025) · Aquatic Toxicology · doi:10.1016/j.aquatox.2025.107625 · Cited by 6 · see citing works
Aqueous solution degradation pathways of trimethylsiloxane surfactants
Mifkovic, M., Etz, B. D., Shukla, M. K., & Vyas, S. (2024) · Environmental Science Advances · doi:10.1039/d4va00256c · Cited by 5 · see citing works
Lotufo, G. R., Boyd, R. E., Krupa, P. M., Zhao, Y., Guelfo, J. E., Simini, M., & Kuperman, R. G. (2025) · Environmental Toxicology and Chemistry · doi:10.1093/etojnl/vgaf083 · Cited by 6 · see citing works
Kikanme, K. N., Karnjanapiboonwong, A., Angappan, R., Dennis, N. M., Hossain, F., Suski, J. G., Salice, C. J., & Anderson, T. A. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.117399 · Cited by 4 · see citing works
Self-citationWeir, S. M., Youssif, M. R., Anderson, T., & Salice, C. J. (2023) · Royal Society of Chemistry eBooks · doi:10.1039/bk9781837670765-00130 · Cited by 4 · see citing works
Self-citationJain, R. B. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-11855-0 · Cited by 4 · see citing works
Roark, K. J., Ackerly, K. L., Hladyniuk, R., & Nielsen, K. M. (2026) · Environmental Pollution · doi:10.1016/j.envpol.2026.129169 · Cited by 2 · see citing works
Lech, M. E., Choi, Y. J., Lee, L., Sepúlveda, M. S., & Hoverman, J. T. (2024) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5877 · Cited by 3 · see citing works
Threshold for increased liver weight is protective of other effects in Peromyscus exposed to PFNA
Narizzano, A. M., Lent, E. M., East, A., Bohannon, M., & Quinn, M. J. (2024) · Toxicological Sciences · doi:10.1093/toxsci/kfae077 · Cited by 2 · see citing works
Self-citationSalice, C. J., East, A., Weible, C., Furst, C. D., Rewerts, J. N., Heron, C. G., & Field, J. A. (2025) · Environmental Toxicology and Chemistry · doi:10.1093/etojnl/vgaf038 · Cited by 1 · see citing works
Self-citationChen, Y., Gattoni, K. M., Paul, E. A., Sullivan, P. J., Valachovic, A. C., & Vogl, L. (2025) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-025-01116-x · Cited by 2 · see citing works
Trophic transfer of per- and polyfluoroalkyl acids in a periphyton-mayfly-zebrafish food chain
Farrell, M. R., Buchwalter, D. B., Weed, R. A., Enders, J. R., & Planchart, A. (2025) · Aquatic Toxicology · doi:10.1016/j.aquatox.2025.107500 · Cited by 1 · see citing works
Gharehveran, M. M., Torres, F., Flores, L., & Anderson, R. H. (2025) · Remediation Journal · doi:10.1002/rem.70040 · Cited by 1 · see citing works
Self-citationA comparative toxicological and epidemiological evaluation of dioxins and PFAS chemicals
Paustenbach, D. J., Kissell, K., & Shakya, A. (2025) · Critical Reviews in Toxicology · doi:10.1080/10408444.2025.2560827 · Cited by 1 · see citing works
Singh, N., Verma, N., & Srivastava, R. (2026) · Environmental Science and Pollution Research · doi:10.1007/s11356-026-37703-1 · Cited by 1 · see citing works
Salas, A. P. S., Ma, Y., Melo, H. D. B., Júnior, É. S., Harrad, S. J., & Rosa, A. H. (2026) · Emerging contaminants · doi:10.1016/j.emcon.2026.100677 · Cited by 1 · see citing works
McCarthy, C., Conder, J., Zodrow, J. M., Zenobio, J. E., Narizzano, A. M., & East, A. (2026) · Integrated Environmental Assessment and Management · doi:10.1093/inteam/vjag080 · Cited by 1 · see citing works
Self-citationVajda, A. M., Jenkins, J. A., Bertolatus, D. W., LeBlanc, D. R., Martyniuk, C. J., Hopkins, Z. R., Tokranov, A. K., Dethloff, A., Tucker, J. C., Lohmann, R., et al. (2026) · Environmental Science & Technology · doi:10.1021/acs.est.6c01726 · Cited by 1 · see citing works
Ackerly, K. L., Walsh, G., Roark, K. J., DiBona, E. R., Osentowski, R., Rivera, T., Lin, L., & Nielsen, K. M. (2026) · Environmental Research · doi:10.1016/j.envres.2026.125346 · Cited by 1 · see citing works
Perfluoroalkyl acid depuration from the edible tissues of a migratory recreationally fished species
Taylor, M. D. (2023) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2023.115593 · Cited by 1 · see citing works
Occurrence of a “Forever Chemical” in the Atmosphere Above Pristine Amazon ForestPreprint
Kourtchev, I., Sebben, B. G., Brill, S., Barbosa, C. G. G., Weber, B., Ferreira, R. R., Dias‐Júnior, C. Q., Popoola, O., Williams, J., Pöhlker, C., et al. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4764251 · Cited by 1 · see citing works
Proposed Harbor Island Seawater Reverse Osmosis Desalination Facility
Nielsen, K. M. (2021) · doi:10.26153/tsw/12029
The Occurrence, Distribution, and Risks of Pfas at Sites Impacted by Firefighting FoamsPreprint
Reinikainen, J., Perkola, N., Äystö, L., & Sorvari, J. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.3998994
Fate and distribution of per and poly fluoroalkyl Substances (PFASs) in the urban environment
Nanjappa, V. (2024) · Queensland University of Technology · doi:10.5204/thesis.eprints.247479
Trophic Transfer of Perfluoroalkyl Acids in a Periphyton-Mayfly-Zebrafish Food ChainPreprint
Farrell, M. R., Buchwalter, D. B., Weed, R. A., Enders, J. R., & Planchart, A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.09.647996
Occurrence, Distribution, and Removal of PFAS in Aquatic Ecosystem
Dhiman, P., Srivstva, A. L., & Kumar, A. (2025) · Emerging contaminants and associated treatment technologies · doi:10.1007/978-3-031-89591-3_15
Fuller, N. W., Kraskura, K., Hrynko, S., Chanov, M. K., Suski, J. G., Choi, Y. J., Lee, L. S., & Salice, C. J. (2026) · Ecotoxicology · doi:10.1007/s10646-026-03027-6
Self-citationPFAS hotspots in Swedish offshore sediments: Regional patterns and sorption dynamics
Niarchos, G., Ruin, E., Josefsson, S., Wiberg, K., & Ahrens, L. (2026) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2026.119807
East, A., Narizzano, A. M., Thomas, S. S., Chandramouli, B., Bazar, M. A., & Holden, L. A. (2026) · ACS Environmental Au · doi:10.1021/acsenvironau.5c00241
Self-citationHayman, N. T., Pandelides, Z., Colvin, M. A., Rosen, G. H., Arblaster, J. A., Anderson, R., & Conder, J. (2026) · Environmental Toxicology and Chemistry · doi:10.1093/etojnl/vgag168
Self-citationFlynn, K. M., Bush, K., Cavallin, J. E., Kasparek, A., Schümann, P., & Villeneuve, D. L. (2026) · Environmental Toxicology and Chemistry · doi:10.1093/etojnl/vgag244
Roark, K. J., Griffitt, R. J., & Nielsen, K. (2026) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2026.110703
Roark, K. J., Ackerly, K. L., Bolser, D. G., & Nielsen, K. M. (2026) · Frontiers in Marine Science · doi:10.3389/fmars.2026.1881663
- Authors
- East, A., Anderson, R. H., & Salice, C. J.
- Affiliations
- Towson University (US)
- United States Air Force (US)
- Corresponding author
- Salice, Christopher J.
- Venue
- Environmental Toxicology and Chemistry
- Publisher
- Oxford University Press (OUP)
- Published
- 2020-10-07
- Volume
- 40
- Issue
- 3
- Pages
- 871-882
- ISSN
- 0730-7268 (ISSN-L)
- 1552-8618
- OpenAlex
- W3092309423
- Cited by
- 89
- References
- 36
- Citations by year
- 2026: 14 · 2025: 15 · 2024: 18 · 2023: 12 · 2022: 16 · 2021: 12 · 2020: 2
- FWCI
- 3.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Environmental Toxicology and Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Strategic Environmental Research and Development Program (ER-2627, ER‐2627)
- Topics
- Physical Sciences › Environmental Science › Environmental Chemistry › Per- and polyfluoroalkyl substances research
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Keywords
- per- and polyfluoroalkyl substances, PFAS mixtures, surface water contamination, aqueous film-forming foam, PFOS, PFHxS, perfluorohexanoic acid, perfluorooctanoic acid, chemical prioritization, toxicity testing, environmental risk assessment, military base environmental contamination
- MeSH terms
- Fluorocarbons, Humans, Water, Water Pollutants, Chemical, Alkanesulfonic Acids, Risk Assessment, Toxicity Tests
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review