Differential alterations of resting‐state functional connectivity in generalized anxiety disorder and panic disorder
Open accessAbstract
Generalized anxiety disorder (GAD) and panic disorder (PD) are most common anxiety disorders with high lifetime prevalence while the pathophysiology and disease‐specific alterations still remain largely unclear. Few studies have taken a whole‐brain perspective in the functional connectivity (FC) analysis of these two disorders in resting state. It limits the ability to identify regionally and psychopathologically specific network abnormalities with their subsequent use as diagnostic marker and novel treatment strategy. The whole brain FC using a novel FC metric was compared, that is, scaled correlation, which they demonstrated to be a reliable FC statistics, but have higher statistical power in two‐sample t ‐test of whole brain FC analysis. About 21 GAD and 18 PD patients were compared with 22 matched control subjects during resting‐state, respectively. It was found that GAD patients demonstrated increased FC between hippocampus/parahippocampus and fusiform gyrus among the most significantly changed FC, while PD was mainly associated with greater FC between somatosensory cortex and thalamus. Besides such regional specificity, it was observed that psychopathological specificity in that the disrupted FC pattern in PD and GAD correlated with their respective symptom severity. The findings suggested that the increased FC between hippocampus/parahippocampus and fusiform gyrus in GAD were mainly associated with a fear generalization related neural circuit, while the greater FC between somatosensory cortex and thalamus in PD were more likely linked to interoceptive processing. Due to the observed regional and psychopathological specificity, their findings bear important clinical implications for the potential treatment strategy. Hum Brain Mapp 37:1459‐1473, 2016 . © 2016 Wiley Periodicals, Inc.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Hippocampus function, structure, and functional connectivity with other regions is compromised in individuals with PTSD, GAD, and PD.
“The hippocampus is another brain structure within the medial temporal lobe whose function, structure, and functional connectivity with other regions is comprised in individuals with PTSD, GAD, and PD (Cui et al, 2016;Fani et al, 2012b;Woon et al, 2010).”
From Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond (2017) · cites this paper as Cui et al, 2016
The FC Alterations in GAD and PD section reports altered hippocampus/parahippocampus connectivity in GAD. The Introduction also reports prior findings of reduced hippocampal volume in GAD and increased hippocampal activation during agoraphobia-specific stimuli in PD. The paper does not establish hippocampal structural or connectivity changes in PD, and it does not address PTSD; page numbers are unavailable in our copy. (LLM, conf=0.87)
Experimental — accuracy not yet measuredRegions of the medial prefrontal cortex (mPFC), including the rostral anterior cingulate cortex, subgenual ACC, and medial frontal gyrus, are heavily connected to the amygdala and hippocampus, and critically involved in emotion regulation, attention bias, and fear extinction in individuals with PTSD and other anxiety disorders.
“Regions of the medial prefrontal cortex (mPFC), including the rostral anterior cingulate cortex, subgenual ACC (sgACC, Brodmann's Area 25) and medial frontal gyrus, are all heavily connected to the amygdala and hippocampus, and critically involved in emotion regulation, attention bias, and fear extinction in individuals with PTSD and other anxiety disorders (Banich et al, 2009;Cui et al, 2016;Et”
From Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond (2017) · cites this paper as Cui et al, 2016
Split into 2 atoms — 0 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 1 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817 · see citing works
Kessler, R. C. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950010008002 · Cited by 12,370 · see citing works
Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.617 · Cited by 12,052 · see citing works
The assessment of anxiety states by rating
HAMILTON, M. (1959) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1959.tb00467.x · Cited by 11,455 · see citing works
Functional connectivity in the motor cortex of resting human brain using echo‐planar mri
Biswal, B., Zerrin Yetkin, F., Haughton, V. M., & Hyde, J. S. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910340409 · Cited by 9,812 · see citing works
The fusiform face area: a module in human extrastriate cortex specialized for face perception
Kanwisher, N., McDermott, J., & Chun, M. M. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-11-04302.1997 · Cited by 7,738 · see citing works
Functional connectivity in the resting brain: a network analysis of the default mode hypothesis
Greicius, M. D., Krasnow, B., Reiss, A. L., & Menon, V. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0135058100 · Cited by 6,358 · see citing works
Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.
Squire, L. R. (1992) · Psychological Review · doi:10.1037/0033-295x.99.2.195 · Cited by 5,376 · see citing works
The distributed human neural system for face perception
Haxby, J. V., Hoffman, E. A., & Gobbini, M. I. (2000) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(00)01482-0 · Cited by 4,891 · see citing works
Neural systems supporting interoceptive awareness
Critchley, H. D., Wiens, S., Rotshtein, P., Öhman, A., & Dolan, R. J. (2004) · Nature Neuroscience · doi:10.1038/nn1176 · Cited by 3,406 · cited 1× · see citing works
“The postcentral gyrus and precentral gyrus have been associated with interoception processing [Critchley et al., 2004; Northoff, 2013; Pollatos et al., 2007].”
Etkin, A., & Wager, T. D. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07030504 · Cited by 3,391 · cited 1× · see citing works
“Abnormal activities in the fusiform gyrus in response to emotional faces have been reported in different anxiety disorders [Etkin and Wager, 2007; Gentili et al., 2008; Schultz et al., 2003; Syal et al., 2012].”
BackgroundContributions of anterior cingulate cortex to behaviour
Devinsky, O., Morrell, M. J., & Vogt, B. A. (1995) · Brain · doi:10.1093/brain/118.1.279 · Cited by 3,377 · see citing works
Interoception: the sense of the physiological condition of the body
(Bud) Craig, A. (2003) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(03)00090-4 · Cited by 2,556 · see citing works
Murphy, K., Birn, R. M., Handwerker, D. A., Jones, T. B., & Bandettini, P. A. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2008.09.036 · Cited by 2,387 · see citing works
Prevalence and Treatment of Mental Disorders, 1990 to 2003
Kessler, R. C., Demler, O., Frank, R. G., Olfson, M., Pincus, H. A., Walters, E. E., Wang, P., Wells, K. B., & Zaslavsky, A. M. (2005) · New England Journal of Medicine · doi:10.1056/nejmsa043266 · Cited by 1,910 · see citing works
The global signal and observed anticorrelated resting state brain networks
Fox, M. D., Zhang, D., Snyder, A. Z., & Raichle, M. E. (2009) · Journal of Neurophysiology · doi:10.1152/jn.90777.2008 · Cited by 1,877 · see citing works
Default-mode brain dysfunction in mental disorders: A systematic review
Broyd, S. J., Demanuele, C., Debener, S., Helps, S. K., James, C. J., & Sonuga-Barke, E. J. S. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.09.002 · Cited by 1,675 · see citing works
The Representation of Object Concepts in the Brain
Martin, A. D. (2006) · Annual Review of Psychology · doi:10.1146/annurev.psych.57.102904.190143 · Cited by 1,576 · see citing works
Yan, C.-G., Cheung, B., Kelly, C., Colcombe, S., Craddock, R. C., Di Martino, A., Li, Q., Zuo, X.-N., Castellanos, F. X., & Milham, M. P. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.03.004 · Cited by 1,461 · see citing works
Self-citationFunctional connectivity in single and multislice echoplanar imaging using resting-state fluctuations
Lowe, M. J., Mock, B. J., & Sorenson, J. A. (1998) · NeuroImage · doi:10.1006/nimg.1997.0315 · Cited by 1,394 · see citing works
Human neural systems for face recognition and social communication
Haxby, J. V., Hoffman, E. A., & Gobbini, M. I. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01330-0 · Cited by 1,287 · see citing works
Kalanit Grill-spector, A., & Malach, R. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144220 · Cited by 1,191 · see citing works
Neuroanatomical Hypothesis of Panic Disorder, Revised
Gorman, J. M., KENT, J. M., Sullivan, G. M., & Coplan, J. D. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.4.493 · Cited by 998 · see citing works
Mineka, S., & Zinbarg, R. (2006) · American Psychologist · doi:10.1037/0003-066x.61.1.10 · Cited by 929 · see citing works
Saad, Z. S., Gotts, S. J., Murphy, K., Chen, G., Jo, H. J., Martin, A., & Cox, R. W. (2012) · Brain Connectivity · doi:10.1089/brain.2012.0080 · Cited by 859 · see citing works
Etkin, A., Prater, K. E., Schatzberg, A. F., Menon, V., & Greicius, M. D. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.104 · Cited by 664 · see citing works
A Neural Circuit for Memory Specificity and Generalization
Xu, W., & Südhof, T. C. (2013) · Science · doi:10.1126/science.1229534 · Cited by 634 · see citing works
Autonomic balance revisited: Panic anxiety and heart rate variability
Friedman, B. H., & Thayer, J. F. (1998) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(97)00202-x · Cited by 616 · cited 2× · see citing works
“…[American Psychiatric Association, 2013] and considerable studies have reported somatic abnormalities in PD, such as increased heart rate, higher skin conductance and increased respiration value [Fleet et al., 1996; Friedman and Thayer, 1998; Hoehn-Saric et al., 2004; Stein and Asmundson, 1994].”
BackgroundDomschke, K., Stevens, S., Pfleiderer, B., & Gerlach, A. L. (2010) · Clinical Psychology Review · doi:10.1016/j.cpr.2009.08.008 · Cited by 580 · see citing works
The thalamus is more than just a relay
Sherman, S. M. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.07.003 · Cited by 559 · see citing works
Etkin, A., Prater, K. E., Hoeft, F., Menon, V., & Schatzberg, A. F. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09070931 · Cited by 550 · see citing works
The role of the fusiform face area in social cognition: implications for the pathobiology of autism
Schultz, R. T., Grelotti, D. J., Klin, A., Kleinman, J., Van der Gaag, C., Marois, R., & Skudlarski, P. (2003) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2002.1208 · Cited by 469 · see citing works
Generalized Anxiety Disorder Is Associated With Overgeneralization of Classically Conditioned Fear
Lissek, S. M., Kaczkurkin, A. N., Rabin, S. J., Geraci, M. F., Pine, D. S., & Grillon, C. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.07.025 · Cited by 462 · see citing works
Cognitive and Perceptual Functions of the Visual Thalamus
Saalmann, Y. B., & Kästner, S. (2011) · Neuron · doi:10.1016/j.neuron.2011.06.027 · Cited by 461 · see citing works
Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder
McClure, E. B., Monk, C. S., Nelson, E. E., Parrish, J. M., Adler, A., Blair, R. J. R., Fromm, S., Charney, D. S., Leibenluft, E., Ernst, M., et al. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.1.97 · Cited by 431 · see citing works
The pathways of interoceptive awareness
Khalsa, S. S., Rudrauf, D., Feinstein, J. S., & Tranel, D. (2009) · Nature Neuroscience · doi:10.1038/nn.2411 · Cited by 387 · see citing works
Altered global brain signal in schizophrenia
Yang, G., Murray, J. D., Repovš, G., Cole, M. W., Savić, A., Glasser, M. F., Pittenger, C., Krystal, J. H., Wang, X., Pearlson, G. D., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1405289111 · Cited by 372 · see citing works
Brain structures mediating cardiovascular arousal and interoceptive awareness
Pollatos, O., Schandry, R., Auer, D. P., & Kaufmann, C. (2007) · Brain Research · doi:10.1016/j.brainres.2007.01.026 · Cited by 351 · see citing works
Contextual fear conditioning in humans: cortical–hippocampal and amygdala contributions
Alvarez, R. P., Biggs, A., Chen, G., Pine, D. S., & Grillon, C. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1246-08.2008 · Cited by 325 · see citing works
Increased cardiac awareness in panic disorder
Ehlers, A., & Breuer, P. (1992) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.101.3.371 · Cited by 315 · see citing works
Etkin, A., & Schatzberg, A. F. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.10091290 · Cited by 311 · see citing works
Lissek, S. (2012) · Depression and Anxiety · doi:10.1002/da.21922 · Cited by 288 · see citing works
Neural basis of individualistic and collectivistic views of self
Chiao, J. Y., Harada, T., Komeda, H., Li, Z., Mano, Y., Saito, D. N., Parrish, T. B., Sadato, N., & Iidaka, T. (2008) · Human Brain Mapping · doi:10.1002/hbm.20707 · Cited by 277 · see citing works
(2004) · PubMed · Cited by 272 · see citing works
Chronic anxiety : generalized anxiety disorder and mixed anxiety-depression
Rapee, R. M., & Barlow, D. H. (1991) · Guilford Press eBooks · Cited by 268 · see citing works
Roy, A. K., Fudge, J. L., Kelly, C. A. M., Perry, J. S. A., Daniele, T., Carlisi, C. O., Benson, B. E., Castellanos, F. X., Milham, M. P., Pine, D. S., et al. (2013) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2012.12.010 · Cited by 267 · see citing works
The hippocampus and contextual memory retrieval in Pavlovian conditioning
Maren, S., & Holt, W. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(99)00188-6 · Cited by 256 · see citing works
Depression uncouples brain hate circuit
Tao, H., Guo, S., Ge, T., Kendrick, K. M., Xue, Z., Liu, Z., & Feng, J. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.127 · Cited by 254 · see citing works
Self-citationNeural substrates of classically conditioned fear-generalization in humans: a parametric fMRI study
Lissek, S. M., Bradford, D. E., Alvarez, R. P., Burton, P. C., Espensen-Sturges, T. D., Reynolds, R. C., & Grillon, C. (2013) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nst096 · Cited by 251 · see citing works
Fleet, R. P., Dupuis, G., Marchand, A., Burelle, D., Arsenault, A., & Beitman, B. D. (1996) · The American Journal of Medicine · doi:10.1016/s0002-9343(96)00224-0 · Cited by 234 · see citing works
Greenberg, T., Carlson, J. M., Cha, J., Hajcak, G., & Mujica-Parodi, L. R. (2012) · Depression and Anxiety · doi:10.1002/da.22016 · Cited by 230 · see citing works
Duncan, N. W., Wiebking, C., & Northoff, G. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.07.016 · Cited by 220 · see citing works
Self-citationHoehn-Saric, R., McLeod, D. R., Funderburk, F., & Kowalski, P. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.9.913 · Cited by 217 · see citing works
Chen, A. C., & Etkin, A. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.122 · Cited by 212 · see citing works
Maggino, F. (2023) · Springer eBooks · doi:10.1007/978-3-031-17299-1_304313 · Cited by 190 · see citing works
(1991) · Cited by 178 · see citing works
Cho, Y. T., Fromm, S., Guyer, A. E., Detloff, A., Pine, D. S., Fudge, J. L., & Ernst, M. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2012.10.013 · Cited by 173 · see citing works
Blair, K. S., Geraci, M. F., Smith, B. W., Hollon, N. G., DeVido, J. J., Otero, M. C., Blair, J., & Pine, D. S. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.04.013 · Cited by 170 · see citing works
Amygdalar atrophy in panic disorder patients detected by volumetric magnetic resonance imaging
Massana, G., Serra-Grabulosa, J. M., Salgado‐Pineda, P., Gastó, C., Junqué, C., Massana, J., Mercader, J. M., Gómez‐Ansón, B., Tobeña, A., & Salamero, M. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00036-3 · Cited by 168 · see citing works
Striatal functional alteration during incentive anticipation in pediatric anxiety disorders
Guyer, A. E., Choate, V. R., Detloff, A., Benson, B., Nelson, E. E., Perez-Edgar, K., Fox, N. A., Pine, D. S., & Ernst, M. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.11010006 · Cited by 165 · see citing works
Smaller amygdala is associated with anxiety in patients with panic disorder
Hayano, F., Nakamura, M., Asami, T., Uehara, K., Yoshida, T., Roppongi, T., Otsuka, T., Inoue, T., & Hirayasu, Y. (2009) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2009.01960.x · Cited by 163 · see citing works
Functional MRI changes during panic anticipation and imagery exposure
Bystritsky, A., Pontillo, D. C., Powers, M. B., Sabb, F. W., Craske, M. G., & Bookheimer, S. Y. (2001) · Neuroreport · doi:10.1097/00001756-200112210-00020 · Cited by 162 · see citing works
Digit Somatotopy within Cortical Areas of the Postcentral Gyrus in Humans
Nelson, A. J., & Chen, R. E. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm257 · Cited by 157 · see citing works
Regional gray matter abnormalities in panic disorder: A voxel-based morphometry study
Uchida, R. R., Del‐Ben, C. M., Busatto, G. F., Duran, F., Guimarães, F. S., Crippa, J. A. S., Araújo, D., dos Santos, A. C., & Graeff, F. G. (2008) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2007.04.015 · Cited by 156 · see citing works
Yassa, M. A., Hazlett, R. L., Stark, C. E. L., & Hoehn-Saric, R. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.04.013 · Cited by 155 · see citing works
Heartbeat perception in panic disorder: a reanalysis
Van der Does, A. J. W., Antony, M. M., Ehlers, A., & Barsky, A. J. (2000) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(98)00184-3 · Cited by 152 · see citing works
EPIDEMIOLOGY, PATTERNS OF COMORBIDITY, AND ASSOCIATED DISABILITIES OF SOCIAL PHOBIA
Wïttchen, H., & Fehm, L. (2001) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70254-9 · Cited by 149 · see citing works
Temporal lobe abnormalities in panic disorder: An MRI study
Fontaine, R., Breton, G., Dery, R., Fontaine, S., & Elie, R. (1990) · Biological Psychiatry · doi:10.1016/0006-3223(90)90004-l · Cited by 138 · see citing works
Cha, J., Greenberg, T., Carlson, J. M., DeDora, D. J., Hajcak, G., & Mujica-Parodi, L. R. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3372-13.2014 · Cited by 137 · see citing works
Superior temporal gyrus volumes in pediatric generalized anxiety disorder
De Bellis, M. D., Keshavan, M. S., Shifflett, H., Iyengar, S., Dahl, R. E., Axelson, D. A., Birmaher, B., Hall, J., Moritz, G., & Ryan, N. D. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01375-0 · Cited by 134 · see citing works
Disrupted Functional Brain Connectivity in Partial Epilepsy: A Resting-State fMRI Study
Luo, C., Qiu, C., Guo, Z., Fang, J., Li, Q., Lei, X., Xia, Y., Lai, Y., Gong, Q., Zhou, D., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0028196 · Cited by 133 · see citing works
Self-citationHattingh, C. J., Ipser, J., Tromp, S. A., Syal, S., Lochner, C., Brooks, S. J., & Stein, D. J. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00347 · Cited by 129 · see citing works
Gentili, C., Gobbini, M. I., Ricciardi, E., Vanello, N., Pietrini, P., Haxby, J. V., & Guazzelli, M. (2008) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2008.08.003 · Cited by 124 · see citing works
Parahippocampal Gray Matter Density in Panic Disorder: A Voxel-Based Morphometric Study
Massana, G., Serra-Grabulosa, J. M., Salgado‐Pineda, P., Gastó, C., Junqué, C., Massana, J., & Mercader, J. M. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.3.566 · Cited by 113 · see citing works
Scaled correlation analysis: a better way to compute a cross‐correlogram
Nikolić, D., Muresan, R. C., Feng, W., & Singer, W. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07987.x · Cited by 111 · see citing works
Anterior cingulate cortex volume reduction in patients with panic disorder
Asami, T., Hayano, F., Nakamura, M., Yamasue, H., Uehara, K., Otsuka, T., Roppongi, T., Nihashi, N., Inoue, T., & Hirayasu, Y. (2008) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2008.01800.x · Cited by 108 · see citing works
Strawn, J. R., Wehry, A. M., Chu, W.-J., Adler, C. M., Eliassen, J. C., Cerullo, M. A., Strakowski, S. M., & DelBello, M. P. (2013) · Depression and Anxiety · doi:10.1002/da.22089 · Cited by 107 · see citing works
Strawn, J. R., Bitter, S. M., Weber, W. A., Chu, W., Whitsel, R. M., Adler, C. M., Cerullo, M. A., Eliassen, J. C., Strakowski, S. M., & DelBello, M. P. (2012) · Depression and Anxiety · doi:10.1002/da.21961 · Cited by 106 · see citing works
Sexually dimorphic gray matter volume reduction in patients with panic disorder
Asami, T., Yamasue, H., Hayano, F., Nakamura, M., Uehara, K., Otsuka, T., Roppongi, T., Nihashi, N., Inoue, T., & Hirayasu, Y. (2009) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2008.10.004 · Cited by 105 · see citing works
Pannekoek, J. N., Veer, I. M., van Tol, M., van der Werff, S. J. A., Demenescu, L. R., Aleman, A., Veltman, D. J., Zitman, F. G., Rombouts, S. A. R. B., & van der Wee, N. J. A. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.07.006 · Cited by 102 · see citing works
Grey matter abnormalities in social anxiety disorder: a pilot study
Syal, S., Hattingh, C. J., Fouché, J., Spottiswoode, B. S., Carey, P. D., Löchner, C., & Stein, D. J. (2012) · Metabolic Brain Disease · doi:10.1007/s11011-012-9299-5 · Cited by 102 · see citing works
Distribution of Dopamine D2-Like Receptors in the Human Thalamus: Autoradiographic and PET Studies
Rieck, R. W., Ansari, M. S., Whetsell, W. O., Deutch, A. Y., & KESSLER, R. M. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300336 · Cited by 100 · see citing works
Pilot multimodal twin imaging study of generalized anxiety disorder
Hettema, J. M., Kettenmann, B., Ahluwalia, V., McCarthy, C., Kates, W. R., Schmitt, J. E., Silberg, J. L., Neale, M. C., Kendler, K. S., & Fatouros, P. P. (2011) · Depression and Anxiety · doi:10.1002/da.20901 · Cited by 91 · see citing works
Chen, X., Duan, M., Xie, Q., Lai, Y., Dong, L., Cao, W., Yao, D., & Luo, C. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.06.014 · Cited by 87 · see citing works
de Carvalho, M. R., Dias, G. P., Cosci, F., Neto, V. L. D. M., Bevilaqua, M. C. D. N., Gardino, P. F., & Nardi, A. E. (2010) · Expert Review of Neurotherapeutics · doi:10.1586/ern.09.161 · Cited by 86 · see citing works
Whole-brain gray matter volume abnormalities in patients with generalized anxiety disorder
Moon, C., Kim, G.-W., & Jeong, G. (2014) · Neuroreport · doi:10.1097/wnr.0000000000000100 · Cited by 80 · see citing works
Altered cingulate white matter connectivity in panic disorder patients
Han, D. H., Renshaw, P. F., Dager, S. R., Chung, A., Hwang, J., Daniels, M. A., Lee, Y. S., & Lyoo, I. K. (2007) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2007.03.002 · Cited by 78 · see citing works
Zhang, F. (2015) · Medical Science Monitor · doi:10.12659/msm.893373 · Cited by 76 · see citing works
Stein, M. B., & Asmundson, G. J. G. (1994) · Biological Psychiatry · doi:10.1016/0006-3223(94)90619-x · Cited by 73 · see citing works
Craig, A. D., & Zhang, E. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.21155 · Cited by 70 · see citing works
Decreased left temporal lobe volume of panic patients measured by magnetic resonance imaging
Uchida, R. R., Del‐Ben, C. M., dos Santos, A. C., Araújo, D., Crippa, J. A. S., Guimarães, F. S., & Graeff, F. G. (2003) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2003000700014 · Cited by 70 · see citing works
Caseras, X., Giampietro, V., Lamas, A., Brammer, M., Vilarroya, O., Carmona, S., Rovira, M., Torrubia, R., & Mataix-Cols, D. (2010) · Psychological Medicine · doi:10.1017/s0033291709005972 · Cited by 69 · see citing works
Rodriguez, B. F., Bruce, S. E., Pagano, M. E., & Keller, M. B. (2004) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2004.10.002 · Cited by 68 · see citing works
Cha, J., Carlson, J. M., DeDora, D. J., Greenberg, T., Proudfit, G. H., & Mujica-Parodi, L. R. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.4868-13.2014 · Cited by 67 · see citing works
Sobanski, T., Wagner, G., Peikert, G., Gruhn, U., Schluttig, K., Sauer, H., & Schlösser, R. G. M. (2010) · Psychological Medicine · doi:10.1017/s0033291709991930 · Cited by 67 · see citing works
Moon, C., & Jeong, G. (2015) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12295 · Cited by 66 · see citing works
Abdallah, C. G., Coplan, J. D., Jackowski, A. P., Sato, J. R., Mao, X., Shungu, D. C., & Mathew, S. J. (2012) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2012.05.009 · Cited by 66 · see citing works
Shin, Y., Džemidžić, M., Jo, H. J., Long, Z., Medlock, C. E., Dydak, U., & Goddard, A. W. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.04.026 · Cited by 53 · see citing works
Accurate heartbeat perception in panic disorder: fact and artefact
van der Does, W. A. J., van Dyck, R., & Spinhoven, P. (1997) · Journal of Affective Disorders · doi:10.1016/s0165-0327(96)01414-0 · Cited by 50 · see citing works
White matter integrity alterations in first episode, treatment-naive generalized anxiety disorder
Zhang, Y., Li, L., Yu, R., Liu, J., Tang, J., Tan, L., Liao, M., Yang, F., & Shan, B. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.11.060 · Cited by 44 · see citing works
Ohrmann, P., Pedersen, A., Braun, M., Bauer, J., Kugel, H., Kersting, A., Domschke, K., Deckert, J., & Suslow, T. (2010) · Depression and Anxiety · doi:10.1002/da.20721 · Cited by 42 · see citing works
Marchand, W. R., Lee, J. N., Healy, L., Thatcher, J. W., Rashkin, E., Starr, J., & Hsu, E. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.10.026 · Cited by 38 · see citing works
A new paradigm (Westphal-Paradigm) to study the neural correlates of panic disorder with agoraphobia
Wittmann, A., Schlagenhauf, F., John, T., Guhn, A., Rehbein, H., Siegmund, A., Stoy, M., Held, D., Schulz, I., Fehm, L., et al. (2010) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-010-0167-1 · Cited by 35 · see citing works
Lai, C., & Wu, Y. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.04.021 · Cited by 33 · see citing works
Gray Matter Deficits in Panic Disorder
Lai, C. (2011) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e31821a1045 · Cited by 32 · see citing works
Wintermann, G.-B., Donix, M., Joraschky, P., Gerber, J., & Petrowski, K. (2013) · PLoS ONE · doi:10.1371/journal.pone.0074655 · Cited by 31 · see citing works
Lai, C., & Wu, Y. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.08.006 · Cited by 24 · see citing works
Complex symptomatology among young women who present with stress‐related problems
Strömbäck, M., Wiklund, M., Renberg, E. S., & Malmgren‐Olsson, E. (2014) · Scandinavian Journal of Caring Sciences · doi:10.1111/scs.12154 · Cited by 16 · see citing works
Kalk, N. J., Melichar, J., Holmes, R., Taylor, L., Daglish, M. R. C., Hood, S. D., Edwards, T., Lenox‐Smith, A., Lingford-Hughes, A. R., & Nutt, D. (2011) · Journal of Psychopharmacology · doi:10.1177/0269881111415730 · Cited by 12 · see citing works
Folias, S. E., Yu, S. P., Snyder, A., Nikolić, D., & Rubin, J. E. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12287 · Cited by 10 · see citing works
[MRI for brain structure and function in patients with first-episode panic disorder].
Zhang, Y., Duan, L. F., Liao, M., Yang, F., Liu, J., Shan, B., & Li, L. (2011) · PubMed · doi:10.3969/j.issn.1672-7347.2011.12.008 · Cited by 8 · see citing works
Flagged first, then by citations
1 of the 113 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Northoff G. 2013. Unlocking the Brain: Coding Volume 1. New York: Oxford University Press.
Cited by
Sorted by citations
Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond
Michopoulos, V., Powers, A., Gillespie, C. F., Ressler, K. J., & Jovanovic, T. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.146 · Cited by 786 · see citing works
From anatomy to function: the role of the somatosensory cortex in emotional regulation
Kropf, E., Syan, S. K., Minuzzi, L., & Frey, B. N. (2018) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2018-0183 · Cited by 382 · see citing works
Psychedelics as Medicines: An Emerging New Paradigm
Nichols, D. E., Johnson, M., & Nichols, C. (2016) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.557 · Cited by 373 · see citing works
Cui, Q., Sheng, W., Chen, Y., Pang, Y., Lu, F., Tang, Q., Han, S., Shen, Q., Wang, Y., Xie, A., et al. (2019) · Human Brain Mapping · doi:10.1002/hbm.24902 · Cited by 159 · see citing works
Kolesar, T. A., Bilevicius, E., Wilson, A. D., & Kornelsen, J. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.102016 · Cited by 157 · see citing works
Biological markers of generalized anxiety disorder
Maron, E., & Nutt, D. (2017) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2017.19.2/dnutt · Cited by 164 · see citing works
Chronic pain and psychedelics: a review and proposed mechanism of action
Castellanos, J. P., Woolley, C., Bruno, K. A., Zeidan, F. Z., Halberstadt, A. L., & Furnish, T. J. (2020) · Regional Anesthesia & Pain Medicine · doi:10.1136/rapm-2020-101273 · Cited by 119 · see citing works
Harrison, L., Kats, A., Williams, M. E., & Aziz‐Zadeh, L. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.00103 · Cited by 117 · see citing works
Structural and functional neuroimaging studies in generalized anxiety disorder: a systematic review
Madonna, D., Delvecchio, G., Soares, J. C., & Brambilla, P. (2019) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2018-0108 · Cited by 99 · see citing works
Schimmenti, A., Starčević, V., Giardina, A., Khazaal, Y., & Billieux, J. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00748 · Cited by 88 · see citing works
Data-Driven Phenotypic Categorization for Neurobiological Analyses: Beyond DSM-5 Labels
Dam, N. T. V., O’Connor, D. A., Marcelle, E. T., Ho, E. J., Craddock, R. C., Tobe, R. H., Gabbay, V., Hudziak, J. J., Castellanos, F. X., LEVENTHAL, B. L., et al. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.06.027 · Cited by 83 · see citing works
Common and distinct brain networks underlying panic and social anxiety disorders
Kim, Y.-K., & Yoon, H.-K. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.06.017 · Cited by 78 · see citing works
Out-of-step: brain-heart desynchronization in anxiety disorders
Tumati, S., Paulus, M. P., & Northoff, G. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01029-w · Cited by 68 · see citing works
Self-citationMaggioni, E., Delvecchio, G., Grottaroli, M., Garzitto, M., Piccin, S., Bonivento, C., Maieron, M., D’Agostini, S., Perna, G., Balestrieri, M., et al. (2019) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2019.06.006 · Cited by 68 · see citing works
Northoff, G., Daub, J., & Hirjak, D. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02245-2 · Cited by 64 · see citing works
Self-citationLi, W., Cui, H., Zhu, Z., Kong, L., Guo, Q., Zhu, Y., Hu, Q., Zhang, L., Li, H., Li, Q., et al. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00549 · Cited by 61 · see citing works
Self-citationMinuzzi, L., Syan, S. K., Smith, M., Hall, A., Hall, G. B., & Frey, B. N. (2017) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867417746001 · Cited by 59 · see citing works
Palma‐Gudiel, H., Córdova‐Palomera, A., Tornador, C., Falcón, C., Bargalló, N., Deco, G., & Fañanás, L. (2018) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2018.03.015 · Cited by 50 · see citing works
Abnormal dynamic functional connectivity density in patients with generalized anxiety disorder
Chen, Y., Cui, Q., Xie, A., Pang, Y., Sheng, W., Tang, Q., Li, D., Huang, J., He, Z., Wang, Y., et al. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.09.084 · Cited by 51 · see citing works
Xiong, H., Guo, R., & Shi, H.-W. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/4048916 · Cited by 50 · see citing works
Machine learning-based discrimination of panic disorder from other anxiety disorders
Na, K., Cho, S., & Cho, S.-J. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.09.027 · Cited by 48 · see citing works
Zugman, A., Jett, L., Antonacci, C., Winkler, A. M., & Pine, D. S. (2023) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2023.102773 · Cited by 35 · see citing works
Shen, Z., Zhu, J., Ren, L., Mingcai, Q., Shao, Y., Yuan, Y., & Shen, X. (2020) · Annals of Translational Medicine · doi:10.21037/atm-20-6448 · Cited by 46 · see citing works
Northoff, G. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-981-32-9705-0_5 · Cited by 45 · see citing works
Self-citationA review of neuroimaging studies in generalized anxiety disorder: “So where do we stand?”
Goossen, B., van der Starre, J., & van der Heiden, C. (2019) · Journal of Neural Transmission · doi:10.1007/s00702-019-02024-w · Cited by 43 · see citing works
Biological Markers of Generalized Anxiety Disorder
Maron, E., & Nutt, D. (2018) · Focus · doi:10.1176/appi.focus.16205 · Cited by 42 · see citing works
Ma, Z., Wang, C., Hines, C. S., Lu, X., Wu, Y., Xu, H., Li, J., Wang, Q., Pang, M., Zhong, Y., et al. (2019) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2019.03.001 · Cited by 40 · see citing works
Self-citationDifferences in cytokines between patients with generalised anxiety disorder and panic disorder
Zou, Z., Zhou, B., Huang, Y., Wang, J., Min, W., & Li, T. (2020) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2020.109975 · Cited by 41 · see citing works
Self-citationCui, H., Zhang, B., Li, W., Li, H., Pang, J., Hu, Q., Zhang, L., Tang, Y., Yang, Z., Wang, J., et al. (2020) · Depression and Anxiety · doi:10.1002/da.23009 · Cited by 38 · see citing works
Self-citationYuan, M., Liu, B., Yang, B., Dang, W., Xie, H., Lui, S., Qiu, C., Zhu, H., & Zhang, W. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.04.099 · Cited by 38 · see citing works
Improving interoceptive ability through the practice of power posing: A pilot study
Weineck, F., Messner, M., Hauke, G., & Pollatos, O. (2019) · PLOS ONE · doi:10.1371/journal.pone.0211453 · Cited by 36 · see citing works
Yao, Z., Liao, M., Hu, T., Zhang, Z., Zhao, Y., Zheng, F., Gutknecht, J., Majoe, D., Hu, B., & Li, L. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00492 · Cited by 35 · see citing works
Topography of the Anxious Self: Abnormal Rest-Task Modulation in Social Anxiety Disorder
Angeletti, L. L., Scalabrini, A., Ricca, V., & Northoff, G. (2021) · The Neuroscientist · doi:10.1177/10738584211030497 · Cited by 35 · see citing works
Self-citationSpatial complexity of brain signal is altered in patients with generalized anxiety disorder
Wang, Y., Wang, X., Ye, L., Yang, Q., Cui, Q., He, Z., Li, L., Yang, X., Zou, Q., Yang, P., et al. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.12.107 · Cited by 28 · see citing works
Cui, H., Jiang, L., Wei, Y., Li, W., Li, H., Zhu, J., Pang, J., Wang, J., & Li, C. (2019) · General Psychiatry · doi:10.1136/gpsych-2019-100051 · Cited by 27 · see citing works
Self-citationAltered resting-state network connectivity in panic disorder: an independent ComponentAnalysis
Ni, M.-F., Zhang, B.-W., Chang, Y., Huang, X., & Wang, X. (2020) · Brain Imaging and Behavior · doi:10.1007/s11682-020-00329-z · Cited by 25 · see citing works
Intrinsic functional brain connectivity patterns underlying enhanced interoceptive sensibility.
Wang, X.-Q., Tan, Y., den Bergh, O. V., von Leupoldt, A., & Qiu, J. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.07.032 · Cited by 20 · see citing works
Altered Brain Signal Variability in Patients With Generalized Anxiety Disorder
Li, L., Wang, Y., Ye, L., Chen, W., Huang, X., Cui, Q., He, Z., Liu, D., & Chen, H. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00084 · Cited by 23 · see citing works
Zammitti, A., Imbrogliera, C., Russo, A., Zarbo, R., & Magnano, P. (2021) · European Journal of Investigation in Health Psychology and Education · doi:10.3390/ejihpe11030050 · Cited by 23 · see citing works
Laicher, H., Int-Veen, I., Torka, F., Kroczek, A., Bihlmaier, I., Storchak, H., Velten-Schurian, K., Dresler, T., Täglich, R., Fallgatter, A. J., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-08579-1 · Cited by 23 · see citing works
Enhanced top-down sensorimotor processing in somatic anxiety
Bouziane, I., Das, M., Friston, K. J., Caballero‐Gaudes, C., & Ray, D. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02061-2 · Cited by 23 · see citing works
Nota, N. M., Burke, S., den Heijer, M., Soleman, R. S., Lambalk, C. B., Cohen‐Kettenis, P. T., Veltman, D. J., & Kreukels, B. P. C. (2017) · Neurophysiologie Clinique · doi:10.1016/j.neucli.2017.09.001 · Cited by 21 · see citing works
Zhang, Z., Liao, M., Yao, Z., Hu, B., Xie, Y., Zheng, W., Hu, T., Zhao, Y., Yang, F., Zhang, Y., et al. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00549 · Cited by 23 · see citing works
Hippocampal circuits underlie improvements in self‐reported anxiety following mindfulness training
Sevinc, G., Greenberg, J., Hölzel, B. K., Gard, T., Calahan, T., Brunsch, V., Hashmi, J. A., Vangel, M. G., Orr, S. P., Milad, M. R., et al. (2020) · Brain and Behavior · doi:10.1002/brb3.1766 · Cited by 23 · see citing works
Chen, Y., Cui, Q., Sheng, W., Tang, Q., Lu, F., Pang, Y., Nan, X., He, Z., Li, D., Lei, T., et al. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2021.110379 · Cited by 22 · see citing works
Yang, F., Fan, L., Zhai, T., Lin, Y., Wang, Y., Ma, J., Liao, M., Zhang, Y., Li, L., Su, L., et al. (2019) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2018.00539 · Cited by 22 · see citing works
Altered brain entropy and functional connectivity patterns in generalized anxiety disorder patients
Fan, S., Yu, Y., Wu, Y., Kai, Y., Wang, H., Chen, Y., Zu, M., Pang, X., & Tian, Y. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.03.062 · Cited by 21 · see citing works
Li, Y., Zhuang, K., Yi, Z., Wei, D., Sun, J., & Qiu, J. (2020) · Psychological Medicine · doi:10.1017/s0033291720002391 · Cited by 20 · see citing works
Guo, X., Yang, F., Fan, L., Gu, Y., Ma, J., Zhang, J., Liao, M., Zhai, T., Zhang, Y., Li, L., et al. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.01.088 · Cited by 19 · see citing works
Self-citationComplex network analysis of brain functional connectivity under a multi-step cognitive task
Cai, S., Chen, W., Liu, D.-B., Tang, M., & Chen, X. (2016) · Physica A Statistical Mechanics and its Applications · doi:10.1016/j.physa.2016.09.058 · Cited by 19 · see citing works
Qi, X., Xu, W., & Li, G. (2023) · Brain Sciences · doi:10.3390/brainsci13091282 · Cited by 18 · see citing works
Mohammadi, M. R., Salmanian, M., Hooshyari, Z., Shakiba, A., Alavi, S. S., Ahmadi, A., Khaleghi, A., Zarafshan, H., Mostafavi, S., Alaghmand, A., et al. (2019) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2019-0416 · Cited by 18 · see citing works
Li, W., Cui, H., Li, H., Colcombe, S. J., Smith, R. C., Cao, X., Pang, J., Hu, Q., Zhang, L., Yang, Z., et al. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114971 · Cited by 17 · see citing works
Self-citationSoehner, A. M., Chase, H. W., Bertocci, M. A., Greenberg, T., Stiffler, R., Lockovich, J. C., Aslam, H. A., Graur, S., Bebko, G. M., & Phillips, M. L. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.07.066 · Cited by 17 · see citing works
Yang, F., Zhang, J., Fan, L., Liao, M., Wang, Y., Chen, C., Zhai, T., Zhang, Y., Li, L., Su, L., et al. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.08.004 · Cited by 17 · see citing works
Self-citationAlbertina, E. A., Barch, D. M., & Karcher, N. R. (2022) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2022.04.001 · Cited by 15 · see citing works
Xu, L., Xu, H., Ding, H., Li, J., & Wang, C. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.647518 · Cited by 14 · see citing works
Self-citationHong, A., Zhou, S., Yang, C. G., Liu, X., Su, S., & Wang, Z. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.02.128 · Cited by 14 · see citing works
Disruptions of salience network during uncertain anticipation of conflict control in anxiety
Han, S., Gao, J., Hu, J., Ye, Y., Huang, H., Liu, J., Liu, M., Ai, H., Qiu, J., Luo, Y., et al. (2023) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2023.103721 · Cited by 12 · see citing works
Garcia‐Ramos, C., Lin, J. J., Bonilha, L., Jones, J. E., Jackson, D. C., Prabhakaran, V., & Hermann, B. P. (2016) · NeuroImage Clinical · doi:10.1016/j.nicl.2016.10.017 · Cited by 12 · see citing works
Dispositional empathy predicts primary somatosensory cortex activity while receiving touch by a hand
Schaefer, M., Kühnel, A., Rumpel, F., & Gärtner, M. (2021) · Scientific Reports · doi:10.1038/s41598-021-90344-x · Cited by 11 · see citing works
Asis‐Cruz, J. D., Kim, J., Krishnamurthy, D., Lopez, C., Kapse, K. J., Andescavage, N. N., Vézina, G., & Limperopoulos, C. (2023) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2023.101282 · Cited by 11 · see citing works
Li, K., Zhang, H., Wang, B., Yang, Y., Zhang, M., Li, W., Li, X., Lv, L., Zhao, J., & Zhang, H. (2020) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2020.1733082 · Cited by 11 · see citing works
Self-citationWang, C., Dyk, K. V., Cho, N. S., Raymond, C., Choi, J. J., Salamon, N., Pope, W. B., Lai, A., Cloughesy, T. F., Nghiemphu, P. L., et al. (2021) · Brain Imaging and Behavior · doi:10.1007/s11682-021-00497-6 · Cited by 10 · see citing works
Zhang, Y., Lin, P., Wang, R., Zhou, J., Xu, X., Wang, J., & Ge, S. (2024) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2024.3497893 · Cited by 10 · see citing works
Self-citationMaron, E., Lan, C.-C., & Nutt, D. (2018) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2018_49 · Cited by 9 · see citing works
Chu, C., Lin, Y., Huang, C. C., Chung, Y., Park, S. Y., Chang, W., Chang, C.-C., & Chang, H. (2025) · Clinical Neurophysiology · doi:10.1016/j.clinph.2025.04.014 · Cited by 9 · see citing works
The Functional Anatomy of Nociception: Effective Connectivity in Chronic Pain and Placebo Response
Nara, S., Baliki, M. N., Friston, K. J., & Ray, D. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.1447-24.2025 · Cited by 9 · see citing works
Distinguishable brain networks relate disease susceptibility to symptom expression in schizophrenia
Liu, Z., Zhang, J., Zhang, K., Zhang, J., Li, X., Cheng, W., Li, M., Zhao, L., Deng, W., Guo, W., et al. (2018) · Human Brain Mapping · doi:10.1002/hbm.24190 · Cited by 9 · see citing works
Self-citationYan, H., Han, Y., Shan, X., Li, H., Liu, F., Xie, G., Li, P., & Guo, W. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.03.047 · Cited by 9 · see citing works
Self-citationTodeva-Radneva, A., Paunova, R., Kandilarova, S., & Stoyanov, D. (2020) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026620666200131095328 · Cited by 9 · see citing works
Regional cortical thinning and cerebral hypoperfusion in patients with panic disorder
Ni, M.-F., Wang, X., Wang, H., Chang, Y., Huang, X., & Zhang, B.-W. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.07.139 · Cited by 8 · see citing works
Temperament clusters associate with anxiety disorder comorbidity in depression
Paavonen, V., Luoto, K. E., Lassila, A., Leinonen, E. V. J., & Kampman, O. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.04.084 · Cited by 7 · see citing works
Gender-Related Brain Activations during an Emotional Task: An fMRI Study
Thomas, M., Gaudeau-Bosma, C., Bouaziz, N., Andrianisaina, P. S.-K., Benadhira, R., Januel, D., & Moulier, V. (2019) · Neuropsychobiology · doi:10.1159/000499977 · Cited by 9 · see citing works
Jiang, J., Li, W., Cui, H., Zhu, Z., Zhang, L., Hu, Q., Li, H., Wang, Y., Pang, J., Wang, Y., et al. (2023) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2023.111656 · Cited by 6 · see citing works
Self-citationLiu, S., Cao, L., Li, H., Du, Y., Wang, M., Xiao, H., Duan, Y., Deng, G., Huang, X., Qiu, C., et al. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.10.006 · Cited by 6 · see citing works
Self-citationRoshani, D., Saboni, K., & Amjadian, M. (2023) · BMC Psychology · doi:10.1186/s40359-023-01283-3 · Cited by 6 · see citing works
Yan, H., Han, Y., Shan, X., Li, H., Liu, F., Xie, G., Li, P., & Guo, W. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109692 · Cited by 5 · see citing works
Self-citationLi, M., Hao, L., Ren, Z., Qiu, J., & Ward, J. (2022) · PLoS ONE · doi:10.1371/journal.pone.0266246 · Cited by 5 · see citing works
Altered functional connectivity between primary and secondary somatosensory areas in panic disorder
Cheng, C., Liu, C.-Y., & Hsu, S. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2020.112808 · Cited by 5 · see citing works
Altered White Matter Network Topology in Panic Disorder
Jiang, M., Zhang, P., Yang, X., Yu, A., Zhang, J., Xu, X., & Li, Z. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13020227 · Cited by 4 · see citing works
Self-citationSarmukadam, K., Bitsika, V., & Sharpley, C. F. (2022) · Advances in Neurodevelopmental Disorders · doi:10.1007/s41252-022-00271-9 · Cited by 4 · see citing works
Wu, H., Zhong, Y., Xu, H., Ding, H., Yuan, S., Wu, Y., Liu, G., Liu, N., & Wang, C. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.853613 · Cited by 4 · see citing works
Han, Y., Yan, H., Li, H., Liu, F., Li, P., Yuan, Y., & Guo, W. (2025) · Journal of Psychopharmacology · doi:10.1177/02698811251362352 · Cited by 3 · see citing works
Self-citationXiao, H., Yuan, M., Cao, Y., Liu, S., Li, H., Cao, L., Shen, D., Li, J., Deng, R., Zhang, W., et al. (2025) · Cerebral Cortex · doi:10.1093/cercor/bhaf278 · Cited by 3 · see citing works
Self-citationYou, L., Jiang, W., Zhang, X., Li, Y., Wei, J., Zhou, Y., Chen, S., Lu, N., Yue, Y., Kong, Y., et al. (2024) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.240016 · Cited by 3 · see citing works
Sievertsen, S. A., Zhu, J., Fang, A., & Forsyth, J. K. (2025) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2025.02.005 · Cited by 3 · see citing works
Gao, Z., Cai, Q., Dong, N., Zhang, S., Bo, Y., & Zhang, J. (2016) · Physica A Statistical Mechanics and its Applications · doi:10.1016/j.physa.2016.05.035 · Cited by 3 · see citing works
Self-citationHe, W., Xiong, H., Fang, J., & Gu, H. (2020) · Annals of Palliative Medicine · doi:10.21037/apm-20-300 · Cited by 3 · see citing works
The response of hippocampal functional connectivity to sustained pain in a pain-sensitive population
Tang, Y., Duan, M., Tan, S., Liu, X., Yao, D., Luo, C., & He, H. (2023) · Brain-Apparatus Communication A Journal of Bacomics · doi:10.1080/27706710.2023.2185105 · Cited by 2 · see citing works
He, Y., Zhang, Y., Jiang, T., Cai, M., Sun, G., Ma, Y., Ji, J., Yang, B., Yang, B., Duan, J., et al. (2025) · BMC Infectious Diseases · doi:10.1186/s12879-024-10397-x · Cited by 2 · see citing works
Chen, Y., Ye, J., Chen, J., Zhen, Z., Tang, C., Ren, S., Han, Q., & Gao, D. (2025) · Nature and Science of Sleep · doi:10.2147/nss.s518104 · Cited by 2 · see citing works
Snell, L., Garner, M. J., Pfeifer, G., & Morriss, J. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.121961 · Cited by 1 · see citing works
Neuroimaging of anxiety disorders
Leicht, G., & Mulert, C. (2020) · doi:10.1093/med/9780198713005.003.0090 · Cited by 1 · see citing works
Lai, C. (2020) · Current Psychiatry Research and Reviews · doi:10.2174/2666082216999200918163245 · Cited by 1 · see citing works
Panic Disorder PD and Agoraphobia: Etiological, Cognitive, and Neuroscientific Aspects
Azab, M. (2022) · Springer eBooks · doi:10.1007/978-3-031-19362-0_3 · Cited by 1 · see citing works
Biomarkers in Anxiety Disorders
Lisboa, J. R., Souza, J. D. R., Gomes, F. V., Guimarães, F. S., & Crippa, J. A. S. (2023) · Springer eBooks · doi:10.1007/978-3-031-43356-6_15 · Cited by 1 · see citing works
Separable and overlapping functional connectome architecture for impulsivity and anxiety
Jung, E. Y., & Kim, M. J. (2024) · Current Psychology · doi:10.1007/s12144-024-07151-6 · Cited by 1 · see citing works
The ventral midline thalamus: Participation in neurological and neuropsychiatric disorders
Cassel, J., Panzer, É., Guimaraes-Olmo, I., Cosquer, B., de Vasconcelos, A. P., & Stéphan, A. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106315 · Cited by 1 · see citing works
Neural Mechanisms Underlying Attention Control In Relation To Anxiety And Depressive SymptomsPreprint
Loh, R. F., Siew, S. K. H., & Yu, J. (2023) · medRxiv · doi:10.1101/2023.11.10.23298383 · Cited by 1 · see citing works
- Authors
- Cui, H., Zhang, J., Liu, Y., Li, Q., Li, H., Zhang, L., Hu, Q., Cheng, W., Luo, Q., Li, J., Li, W., Wang, J., Feng, J., Li, C., & Northoff, G.
- Affiliations
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Tongji University (CN)
- East China Normal University (CN)
- University of Ottawa (CA)
- ORCID
- Venue
- Human Brain Mapping
- Publisher
- Wiley
- Published
- 2016-01-23
- Volume
- 37
- Issue
- 4
- Pages
- 1459-1473
- ISSN
- 1065-9471 (ISSN-L)
- 1097-0193
- PMC
- PMC6867341
- OpenAlex
- W2301327842
- Cited by
- 123
- References
- 113
- Citations by year
- 2026: 11 · 2025: 11 · 2024: 8 · 2023: 17 · 2022: 8 · 2021: 10 · 2020: 21 · 2019: 16 · 2018: 7 · 2017: 7 · 2016: 7
- FWCI
- 7.85
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Human Brain Mapping (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (2011-873, 81071098, 13dz2260500, 61573107, 61104143, OMA-MH, 2011-873)
- Shanghai Municipal Health Bureau
- Canadian Institutes of Health Research
- NIH Clinical Center
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- generalized anxiety disorder, panic disorder, resting-state functional connectivity, hippocampus, parahippocampal gyrus, fusiform gyrus, somatosensory cortex, thalamus, fear generalization, interoceptive processing, symptom severity, anxiety disorders
- MeSH terms
- Adult, Anxiety Disorders, Brain, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Nerve Net, Rest, Panic Disorder
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
