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The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae.
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Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
Basic local alignment search tool
Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990) · Journal of Molecular Biology · doi:10.1006/jmbi.1990.9999 · Cited by 98,669
Predicting coiled coils from protein sequences.
Lupas, A., Van Dyke, M., & Stock, J. (1991) · Science · doi:10.1126/science.252.5009.1162 · Cited by 3,953
Cited by
Rab proteins as membrane organizers
Zerial, M., & McBride, H. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35052055 · Cited by 3,381
Role of Rab GTPases in Membrane Traffic and Cell Physiology
Hutagalung, A. H., & Novick, P. J. (2011) · Physiological Reviews · doi:10.1152/physrev.00059.2009 · Cited by 1,460
Self-citationRabs and their effectors: achieving specificity in membrane traffic
Grosshans, B. L., Ortiz, D., & Novick, P. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601617103 · Cited by 1,005
Self-citationBurgoyne, R. D., & Morgan, A. (2003) · Physiological Reviews · doi:10.1152/physrev.00031.2002 · Cited by 934
Adaptation of core mechanisms to generate cell polarity
Nelson, W. J. (2003) · Nature · doi:10.1038/nature01602 · Cited by 716
Building epithelial architecture: insights from three-dimensional culture models
O'Brien, L. E., Zegers, M. M. P., & Mostov, K. E. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm859 · Cited by 596
Grindstaff, K. K., Yeaman, C., Anandasabapathy, N., Hsu, S.-C., Rodriguez-Boulan, E., Scheller, R. H., & Nelson, W. J. (1998) · Cell · doi:10.1016/s0092-8674(00)81435-x · Cited by 460
The exocyst complex in polarized exocytosis
He, B., & Guo, W. (2009) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2009.04.007 · Cited by 438
Wurmser, A. E., Sato, T. K., & Emr, S. D. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.3.551 · Cited by 425
Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion
Lang, J. (1999) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1999.00043.x · Cited by 347
Boyd, C., Hughes, T., Pypaert, M., & Novick, P. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200408124 · Cited by 312
Self-citationCdc42 Interacts with the Exocyst and Regulates Polarized Secretion
Zhang, X., Bi, E., Novick, P., Du, L., Kozminski, K. G., Lipschutz, J. H., & Guo, W. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m107464200 · Cited by 307
Self-citationThe exocyst defrocked, a framework of rods revealed
Munson, M., & Novick, P. (2006) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1097 · Cited by 290
Self-citationThe exocyst complex binds the small GTPase RalA to mediate filopodia formation
Sugihara, K., Asano, S., Tanaka, K., Iwamatsu, A., Okawa, K., & Ohta, Y. (2002) · Nature Cell Biology · doi:10.1038/ncb720 · Cited by 258
Sec15 Is an Effector for the Rab11 GTPase in Mammalian Cells
Zhang, X.-M., Ellis, S., Sriratana, A., Mitchell, C. A., & Rowe, T. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402264200 · Cited by 257
Ral-GTPases: approaching their 15 minutes of fame.
Feig, L. A. (2003) · Trends in Cell Biology · doi:10.1016/s0962-8924(03)00152-1 · Cited by 249
Wu, B., & Guo, W. (2015) · Journal of Cell Science · doi:10.1242/jcs.156398 · Cited by 240
Ergosterol is required for targeting of tryptophan permease to the yeast plasma membrane
Umebayashi, K., & Nakano, A. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200303088 · Cited by 230
Exocytosis: The Many Masters of the Exocyst
Lipschutz, J. H., & Mostov, K. E. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00753-4 · Cited by 225
Wilson, P. M., Fryer, R. H., Fang, Y., & Hatten, M. E. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0032-10.2010 · Cited by 169
Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport
Monier, S., Jollivet, F., Janoueix‐Lerosey, I., Johannes, L., & Goud, B. (2002) · Traffic · doi:10.1034/j.1600-0854.2002.030406.x · Cited by 170
Cryo-EM structure of the exocyst complex
Mei, K., Li, Y., Wang, S., Shao, G., Wang, J., Ding, Y., Luo, G., Yue, P., Liu, J.-J., Wang, X., et al. (2018) · Nature Structural & Molecular Biology · doi:10.1038/s41594-017-0016-2 · Cited by 156
Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane
Gerges, N. Z., Backos, D. S., Rupasinghe, C. N., Spaller, M. R., & Esteban, J. A. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601065 · Cited by 147
Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase
Jin, R., Junutula, J. R., Matern, H. T., Ervin, K. E., Scheller, R. H., & Brunger, A. T. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600699 · Cited by 145
The Brain Exocyst Complex Interacts with RalA in a GTP-dependent Manner
Brymora, A., Valova, V. A., Larsen, M. R., Roufogalis, B. D., & Robinson, P. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.c100320200 · Cited by 143
Mehta, S. Q., Hiesinger, P. R., Beronja, S., Zhai, R. G., Schulze, K. L., Verstreken, P., Cao, Y., Zhou, Y., Tepass, U., Crair, M. C., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.029 · Cited by 136
Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex
Fukai, S., Matern, H. T., Jagath, J. R., Scheller, R. H., & Brunger, A. T. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg329 · Cited by 126
PI(4,5)P2-binding effector proteins for vesicle exocytosis
Martin, T. F. J. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.09.017 · Cited by 124
Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action
Hillenmeyer, M. E., Ericson, E., Davis, R. W., Nislow, C., Koller, D., & Giaever, G. (2010) · Genome Biology · doi:10.1186/gb-2010-11-3-r30 · Cited by 112
“Our preliminary genetic data indicating a novel interaction between Cox17 and clozapine are tantalizing given the renewed interest in this drug [61], and deserve further investigation.”
BackgroundDupraz, S., Grassi, D., Bernis, M. E., Sosa, L., Bisbal, M., Gastaldi, L., Jausoro, I., Cáceres, A., Pfenninger, K. H., & Quiroga, S. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3907-09.2009 · Cited by 111
Minireview: How Peptide Hormone Vesicles Are Transported to the Secretion Site for Exocytosis
Park, J. J., & Loh, Y. P. (2008) · Molecular Endocrinology · doi:10.1210/me.2008-0209 · Cited by 81
Exposing the Elusive Exocyst Structure
Lepore, D. M., Martínez-Núñez, L., & Munson, M. (2018) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2018.06.012 · Cited by 74
RalA-Exocyst Interaction Mediates GTP-dependent Exocytosis
Wang, L., Li, G., & Sugita, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400522200 · Cited by 68
Roy, D., & Tedeschi, A. (2021) · Cells · doi:10.3390/cells10051078 · Cited by 68
Sterol biosensor reveals LAM-family Ltc1-dependent sterol flow to endosomes upon Arp2/3 inhibition
Marek, M., Vincenzetti, V., & Martin, S. G. (2020) · Journal of Cell Biology · doi:10.1083/jcb.202001147 · Cited by 50
Regulation of Platelet Dense Granule Secretion by the Ral GTPase-Exocyst Pathway
Kawato, M., Shirakawa, R., Kondo, H., Higashi, T., Ikeda, T., Okawa, K., Fukai, S., Nureki, O., Kita, T., & Horiuchi, H. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m705340200 · Cited by 46
Krause, G. J., Diaz, A., Jafari, M., Khawaja, R. R., Agullo‐Pascual, E., Santiago‐Fernández, O., Richards, A. L., Chen, K., Dmitriev, P., Sun, Y., et al. (2022) · Aging Cell · doi:10.1111/acel.13713 · Cited by 35
A lineage-specific Exo70 is required for receptor kinase–mediated immunity in barley
Holden, S., Bergum, M., Green, P., Bettgenhaeuser, J., Hernández-Pinzón, I., Thind, A., Clare, S., Russell, J. M., Hubbard, A., Taylor, J., et al. (2022) · Science Advances · doi:10.1126/sciadv.abn7258 · Cited by 29
Alberts, P., & Galli, T. (2003) · Biology of the Cell · doi:10.1016/s0248-4900(03)00074-1 · Cited by 23
Beattie, S. R., Schnicker, N. J., Murante, T., Kettimuthu, K., Williams, N. S., Gakhar, L., & Krysan, D. J. (2020) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.9b00478 · Cited by 10
Singh, D., Liu, Y., Zhu, Y.-H., Zhang, S., Naegele, S. M., & Wu, J.-Q. (2025) · eLife · doi:10.7554/elife.101113 · Cited by 8
Singh, D., Liu, Y., Zhu, Y.-H., Zhang, S., Naegele, S. M., & Wu, J.-Q. (2025) · eLife · doi:10.7554/elife.101113.3 · Cited by 3
Metadata
- Authors
- TerBush, D. R., Maurice, T., Roth, D., & Novick, P.
- Venue
- The EMBO Journal
- Published
- 1996-12
- Volume
- 15
- Issue
- 23
- Pages
- 6483-6494
- ISSN
- 0261-4189 (ISSN-L)
- OpenAlex
- W1508614407
- Cited by
- 852
- References
- 4
- FWCI
- 8.84
- Type
- journal article
- Language
- en
- Open access
- bronze
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