The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Traumatic brain injury alters expression of hippocampal microRNAs: Potential regulators of multiple pathophysiological processes
Abstract
Multiple cellular, molecular, and biochemical changes contribute to outcome after traumatic brain injury (TBI). MicroRNAs (miRNAs) are known to influence many important cellular processes, including proliferation, apoptosis, neurogenesis, angiogenesis, and morphogenesis, all processes that are involved in TBI pathophysiology. However, it has not yet been determined whether miRNA expression is altered after TBI. In the present study, we used a microarray platform to examine changes in the hippocampal expression levels of 444 verified rodent miRNAs at 3 and 24 hr after controlled cortical impact injury. Our analysis found 50 miRNAs exhibited decreased expression levels and 35 miRNAs exhibited increased expression levels in the hippocampus after injury. We extended the microarray findings using quantitative polymerase chain reaction analysis for a subset of the miRNAs with altered expression levels (miR‐107, ‐130a, ‐223, ‐292‐5p, ‐433‐3p, ‐451, ‐541, and ‐711). Bioinformatic analysis of the predicted targets for this panel of miRNAs revealed an overrepresentation of proteins involved in several biological processes and functions known to be initiated after injury, including signal transduction, transcriptional regulation, proliferation, and differentiation. Our results indicate that multiple protein targets and biological processes involved in TBI pathophysiology may be regulated by miRNAs. © 2008 Wiley‐Liss, Inc.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
miR-107 and miR-155 are cytosolic miRNAs that have been shown to be altered in TBI.
“Interestingly, we did not find any evidence supporting the inter-organelle shift of other miRNAs such as miR-107, or miR-155, although these cytosolic miRNAs have been shown to be altered in TBI [31, 72].”
From The Mitochondria-Associated ER Membranes Are Novel Subcellular Locations Enriched for Inflammatory-Responsive MicroRNAs (2020) · cites this paper as [72]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Combinatorial microRNA target predictions
Krek, A., Grün, D., Poy, M. N., Wolf, R., Rosenberg, L., Epstein, E. J., MacMenamin, P., da Piedade, I., Gunsalus, K. C., Stoffel, M., et al. (2005) · Nature Genetics · doi:10.1038/ng1536 · Cited by 4,603
The impact of microRNAs on protein output
Baek, D., Villén, J., Shin, C., Camargo, F. D., Gygi, S. P., & Bartel, D. P. (2008) · Nature · doi:10.1038/nature07242 · Cited by 3,592
Xie, X., Lu, J., Kulbokas, E. J., Golub, T. R., Mootha, V., Lindblad-Toh, K., Lander, E. S., & Kellis, M. (2005) · Nature · doi:10.1038/nature03441 · Cited by 1,872
A controlled cortical impact model of traumatic brain injury in the rat
Edward Dixon, C., Clifton, G. L., Lighthall, J. W., Yaghmai, A. A., & Hayes, R. L. (1991) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(91)90104-8 · Cited by 1,141
Illuminating the silence: understanding the structure and function of small RNAs
Rana, T. M. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2085 · Cited by 1,083
Stark, A., Brennecke, J., Bushati, N., Russell, R. B., & Cohen, S. M. (2005) · Cell · doi:10.1016/j.cell.2005.11.023 · Cited by 1,080
GenePaint.org: an atlas of gene expression patterns in the mouse embryo
Visel, A. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh029 · Cited by 528
Flagged first, then by citations
Research works printed but not linked: 59
- 10.1016/j.cell.2008.05.045 · DOI
- 10.1177/1073858407305850 · DOI
- 10.1038/ng1914 · DOI · Paper page
- 10.1093/nar/gkm995 · DOI
- 10.1093/bioinformatics/19.2.185 · DOI
- 10.1038/nsmb1167 · DOI
- 10.1371/journal.pbio.0030085 · DOI
- 10.1261/rna.7135204 · DOI
- 10.1016/S0959-4388(02)00356-2 · DOI
- 10.1111/j.1365-2818.2005.01450.x · DOI
- 10.1182/blood-2007-07-104133 · DOI
- 10.1023/B:NERE.0000023614.30084.eb · DOI
- 10.1038/ng1855 · DOI
- 10.1016/j.tig.2007.09.001 · DOI
- 10.1016/j.cell.2005.09.023 · DOI · Paper page
- 10.1038/35888 · DOI · Paper page
- 10.1002/bip.20005 · DOI
- 10.1128/MCB.19.3.1720 · DOI · Paper page
- 10.1161/STROKEAHA.107.500736 · DOI
- 10.1161/CIRCRESAHA.106.141986 · DOI
- 10.1016/j.tem.2007.10.001 · DOI
- 10.1371/journal.pbio.0020363 · DOI · Paper page
- 10.1038/nature06607 · DOI · Paper page
- 10.1073/pnas.0709971104 · DOI · Paper page
- 10.1016/j.devcel.2006.09.009 · DOI · Paper page
- 10.1038/nmeth843 · DOI · Paper page
- 10.1016/S0169-328X(02)00331-5 · DOI
- 10.1161/CIRCRESAHA.107.153916 · DOI
- 10.1016/j.ydbio.2007.07.012 · DOI
- 10.1261/rna.480407 · DOI
- 10.1038/sj.emboj.7600385 · DOI
- 10.1016/S0092-8674(03)01018-3 · DOI · Paper page
- 10.1016/j.cell.2004.12.035 · DOI · Paper page
- 10.1038/nature03315 · DOI · Paper page
- 10.1016/j.nlm.2007.08.018 · DOI
- 10.1016/S0006-8993(02)04149-5 · DOI
- 10.1016/j.bbrc.2007.10.077 · DOI · Paper page
- 10.1093/hmg/ddn201 · DOI · Paper page
- 10.1093/nar/gkj141 · DOI
- 10.1111/j.1750-3639.2007.00120.x · DOI
- 10.1093/nar/gki107 · DOI
- 10.1101/gr.1680803 · DOI
- 10.1182/blood-2006-01-012369 · DOI
- 10.1002/dneu.20584 · DOI
- 10.1111/j.1750-3639.2004.tb00056.x · DOI
- 10.1038/ng1798 · DOI
- 10.1016/j.nec.2006.10.007 · DOI
- 10.1161/01.RES.0000265065.26744.17 · DOI
- 10.1093/nar/gnj009 · DOI
- 10.1093/cvr/cvn156 · DOI · Paper page
- 10.1016/S0079-6123(06)61021-2 · DOI
- 10.1111/j.1460-9568.2006.05037.x · DOI
- 10.1523/JNEUROSCI.5065-07.2008 · DOI · Paper page
- 10.1016/S0024-3205(01)01461-8 · DOI
- 10.1074/jbc.M413394200 · DOI
- 10.1002/dvdy.20441 · DOI
- 10.1016/j.exphem.2007.03.014 · DOI
- 10.1016/j.brainres.2008.05.085 · DOI
- 10.1007/978-1-59745-304-2_19 · DOI
Cited by
Sorted by citations
MicroRNA signature in diabetic wound healing: promotive role of miR‐21 in fibroblast migration
Madhyastha, R., Madhyastha, H., Nakajima, Y., Omura, S., & Maruyama, M. (2012) · International Wound Journal · doi:10.1111/j.1742-481x.2011.00890.x · Cited by 168
Harrison, E. B., Hochfelder, C. G., Lamberty, B. G., Meays, B. M., Morsey, B. M., Kelso, M. L., Fox, H. S., & Yelamanchili, S. V. (2016) · FEBS Open Bio · doi:10.1002/2211-5463.12092 · Cited by 151
Wong, V. S., & Langley, B. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.04.009 · Cited by 85
Ge, X., Li, W., Huang, S., Yin, Z., Yang, M., Han, Z., Han, Z., Chen, F., Wang, H., Lei, P., et al. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2018.5728 · Cited by 77
Depletion of GGA1 and GGA3 Mediates Postinjury Elevation of BACE1
Walker, K. R., Kang, E. L., Whalen, M. J., Shen, Y., & Tesco, G. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.5491-11.2012 · Cited by 66
Wang, W.-X., Prajapati, P., Nelson, P. T., & Springer, J. E. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-01937-y · Cited by 49
Induction of miR-155 after Brain Injury Promotes Type 1 Interferon and has a Neuroprotective Effect
Harrison, E. B., Emanuel, K., Lamberty, B. G., Morsey, B. M., Li, M., Kelso, M. L., Yelamanchili, S. V., & Fox, H. S. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00228 · Cited by 48
Down-Regulation of miR-23a-3p Mediates Irradiation-Induced Neuronal Apoptosis
Sabirzhanov, B., Makarevich, O., Barrett, J., Jackson, I. L., Faden, A. I., & Stoica, B. A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21103695 · Cited by 31
Metadata
- Authors
- Redell, J. B., Liu, Y., & Dash, P. K.
- Venue
- Journal of Neuroscience Research
- Publisher
- Wiley
- Published
- 2008-11-19
- Volume
- 87
- Issue
- 6
- Pages
- 1435-1448
- ISSN
- 0360-4012
- 1097-4547
- PMC
- PMC5980641
- Cited by
- 185
- References
- 7
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
