Systematic review and meta-analyses of randomized controlled trials examining tinnitus management.
Open accessAbstract
OBJECTIVES/HYPOTHESIS: To evaluate the existing level of evidence for tinnitus management strategies identified in the UK Department of Health's Good Practice Guideline. STUDY DESIGN: Systematic review of peer-reviewed literature and meta-analyses. METHODS: Searches were conducted in PubMed, Cambridge Scientific Abstracts, Web of Science, and EMBASE (earliest to August 2010), supplemented by hand searches in October 2010. Only randomized controlled trials that used validated questionnaire measures of symptoms (i.e., measures of tinnitus distress, anxiety, depression) were included. RESULTS: Twenty-eight randomized controlled trials met our inclusion criteria, most of which provide moderate levels of evidence for the effects they reported. Levels of evidence were generally limited by the lack of blinding, lack of power calculations, and incomplete data reporting in these studies. Only studies examining cognitive behavioral therapy were numerous and similar enough to perform meta-analysis, from which the efficacy of cognitive behavioral therapy (moderate effect size) appears to be reasonably established. Antidepressants were the only drug class to show any evidence of potential benefit. CONCLUSIONS: The efficacy of most interventions for tinnitus benefit remains to be demonstrated conclusively. In particular, high-level assessment of the benefit derived from those interventions most commonly used in practice, namely hearing aids, maskers, and tinnitus retraining therapy needs to be performed.
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Clinical psychologist-delivered CBT is superior to other treatments and waiting list control conditions for improving tinnitus-related distress, depression, and quality of life.
“Research evidence consistently demonstrates a superiority of clinical psychologist-delivered CBT over other treatments and waiting list control conditions for improving tinnitus-related distress, depression, and quality of life (Martinez-Devesa et al. 2010; Hesser et al. 2011; Hoare et al. 2011).”
From Psychological Therapy for People with Tinnitus: A Scoping Review of Treatment Components. (2017) · cites this paper as Hoare et al. 2011
The Results (Cognitive Behavioral Therapy; page unavailable) report that psychologist-delivered CBT improved tinnitus distress measures compared with education, relaxation, and waiting-list controls. But the review finds little evidence of benefit for depression and does not establish the claimed improvement in quality of life. (LLM, conf=0.90)
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- Authors
- Hoare, D. J., Kowalkowski, V. L., Kang, S., & Hall, D. A.
- Affiliations
- University of Nottingham (GB)
- Nottingham Trent University (GB)
- Corresponding author
- Hoare, Derek J.
- Venue
- The Laryngoscope
- Publisher
- Wiley
- Published
- 2011-06-10
- Volume
- 121
- Issue
- 7
- Pages
- 1555-1564
- ISSN
- 0023-852X (ISSN-L)
- 1531-4995
- PMC
- PMC3477633
- OpenAlex
- W2088018963
- Cited by
- 255
- References
- 60
- Citations by year
- 2026: 7 · 2025: 12 · 2024: 13 · 2023: 12 · 2022: 25 · 2021: 16 · 2020: 17 · 2019: 17 · 2018: 18 · 2017: 20 · 2016: 21 · 2015: 16 · 2014: 20 · 2013: 18 · 2012: 17
- FWCI
- 2.48
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Laryngoscope (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Spiral (Imperial College London) (submittedVersion)
- Funders
- National Institute for Health and Care Research
- Topics
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
- Health Sciences › Health Professions › Speech and Hearing › Noise Effects and Management
- Keywords
- tinnitus management, cognitive behavioral therapy, antidepressants, tinnitus retraining therapy, hearing aids, tinnitus maskers, tinnitus distress, anxiety, depression, treatment efficacy, level of evidence
- MeSH terms
- Adaptation, Psychological, Combined Modality Therapy, Counseling, Female, Hearing Aids, Humans, Male, Quality of Life, Relaxation Therapy, Severity of Illness Index, Tinnitus, Cognitive Behavioral Therapy, Treatment Outcome, Disease Progression, Risk Assessment
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