Docosahexaenoic acid attenuates adipose tissue angiogenesis and insulin resistance in high fat diet‐fed middle‐aged mice via a sirt1‐dependent mechanism

Obesity is associated with macrophage accumulation in adipose tissue

Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041 · see citing works

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760 · see citing works

Obesity as a medical problem

Kopelman, P. G. (2000) · Nature · doi:10.1038/35007508 · Cited by 4,795 · see citing works

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ

Picard, F., Kurtev, M. V., Chung, N., Topark‐Ngarm, A., Senawong, T., de Oliveira, R. M., Leid, M. E., McBurney, M. W., & Guarente, L. (2004) · Nature · doi:10.1038/nature02583 · Cited by 1,943 · see citing works

Adipose tissue remodeling and obesity

Sun, K., Kusminski, C. M., & Scherer, P. E. (2011) · Journal of Clinical Investigation · doi:10.1172/jci45887 · Cited by 1,941 · see citing works

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Milne, J. C., Lambert, P. D., Schenk, S., Carney, D. P., Smith, J. J., Gagne, D. J., Jin, L., Boss, O., Perni, R. B., Vu, C. B., et al. (2007) · Nature · doi:10.1038/nature06261 · Cited by 1,707 · see citing works

The cellular and signaling networks linking the immune system and metabolism in disease

Osborn, O., & Olefsky, J. M. (2012) · Nature Medicine · doi:10.1038/nm.2627 · Cited by 1,551 · see citing works

The Sir2 Family of Protein Deacetylases

Blander, G., & Guarente, L. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073651 · Cited by 1,496 · see citing works

Adipose Tissue Hypoxia in Obesity and Its Impact on Adipocytokine Dysregulation

Hosogai, N., Fukuhara, A., Oshima, K., Miyata, Y., Tanaka, S., Segawa, K., Furukawa, S., Tochino, Y., Komuro, R., Matsuda, M., et al. (2007) · Diabetes · doi:10.2337/db06-0911 · Cited by 1,257 · see citing works

White Fat Progenitor Cells Reside in the Adipose Vasculature

Tang, W., Zeve, D., Suh, J. M., Bosnakovski, D., Kyba, M., Hammer, R. E., Tallquist, M. D., & Graff, J. M. (2008) · Science · doi:10.1126/science.1156232 · Cited by 1,113 · see citing works

A Paracrine Loop Between Adipocytes and Macrophages Aggravates Inflammatory Changes: Role of Free Fatty Acids and Tumor Necrosis Factor α

Suganami, T., Nishida, J., & Ogawa, Y. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000183883.72263.13 · Cited by 1,056 · see citing works

Calorie restriction, SIRT1 and metabolism: understanding longevity

Bordone, L., & Guarente, L. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1616 · Cited by 1,021 · see citing works

Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity

Lumeng, C. N., DeYoung, S. M., Bodzin, J. L., & Saltiel, A. R. (2007) · Diabetes · doi:10.2337/db06-1076 · Cited by 1,016 · see citing works

Sirt1 protects against high-fat diet-induced metabolic damage

Pfluger, P. T., Herranz, D., Velasco-Miguel, S., Serrano, M., & Tschöp, M. H. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802917105 · Cited by 932 · see citing works

Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue

Halberg, N., Khan, T., Trujillo, M. E., Wernstedt-Asterholm, I., Attie, A. D., Sherwani, S., Wang, Z. V., Landskroner-Eiger, S., Dineen, S., Magalang, U. J., et al. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00192-09 · Cited by 896 · see citing works

Adipose tissue mass can be regulated through the vasculature

Rupnick, M. A., Panigrahy, D., Zhang, C.-Y., Dallabrida, S. M., Lowell, B. B., Langer, R., & Folkman, M. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.162349799 · Cited by 845 · see citing works

SIRT1 Improves Insulin Sensitivity under Insulin-Resistant Conditions by Repressing PTP1B

Sun, C., Zhang, F., Ge, X., Yan, T., Chen, X., Shi, X., & Zhai, Q. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.08.014 · Cited by 766 · see citing works

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

Lim, J.-H., Lee, Y.-M., Chun, Y.-S., Chen, J., Kim, J.-E., & Park, J.-W. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.05.023 · Cited by 758 · see citing works

Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice

Moynihan, K. A., Grimm, A. A., Plueger, M. M., Bernal‐Mizrachi, E., Ford, E. L., CRAS-MÉNEUR, C. M. H., Permutt, M. A., & Imai, S. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.07.001 · Cited by 630 · see citing works

SIRT1 Controls Endothelial Angiogenic Functions During Vascular Growth

Potente, M., Ghaeni, L., Baldessari, D., Mostoslavsky, R., Rossig, L., Dequiedt, F., Haendeler, J., Mione, M., Dejana, E., Alt, F. W., et al. (2007) · Genes & Development · doi:10.1101/gad.435107 · Cited by 608 · see citing works

Increased Infiltration of Macrophages in Omental Adipose Tissue Is Associated With Marked Hepatic Lesions in Morbid Human Obesity

Cancello, R., Tordjman, J., Poitou, C., Guilhem, G., Bouillot, J. L., Hugol, D., Coussieu, C., Basdevant, A., Hen, A. B., Bedossa, P., et al. (2006) · Diabetes · doi:10.2337/db06-0133 · Cited by 607 · see citing works

Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity?

Trayhurn, P., Wang, B., & Wood, I. S. (2008) · British Journal of Nutrition · doi:10.1017/s0007114508971282 · Cited by 464 · see citing works

Inflamed fat: what starts the fire?

Neels, J. G. (2005) · Journal of Clinical Investigation · doi:10.1172/jci27280 · Cited by 463 · see citing works

Erythropoietin Is a Paracrine Mediator of Ischemic Tolerance in the Brain: Evidence from anIn VitroModel

Ruscher, K., Freyer, D., Karsch, M., Исаев, Н. К., Megow, D., Sawitzki, B., Priller, J., Dirnagl, U., & Meisel, A. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-23-10291.2002 · Cited by 462 · see citing works

Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF

Cao, R., Brakenhielm, E., Wahlestedt, C., Thyberg, J., & Cao, Y. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.101564798 · Cited by 446 · see citing works

Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

Unger, R. H., & Scherer, P. E. (2010) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2010.01.009 · Cited by 436 · see citing works

CXCL8/IL8 Stimulates Vascular Endothelial Growth Factor (VEGF) Expression and the Autocrine Activation of VEGFR2 in Endothelial Cells by Activating NFκB through the CBM (Carma3/Bcl10/Malt1) Complex

Martı́n, D., Galisteo, R., & Gutkind, J. S. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.c800207200 · Cited by 389 · see citing works

Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation

Xue, Y., Petrovič, N., Cao, R., Larsson, O. S., Lim, S., Chen, S., Feldmann, H. M., Liang, Z., Zhu, Z., Nedergaard, J., et al. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2008.11.009 · Cited by 379 · see citing works

SIRT1 Regulates Adiponectin Gene Expression through Foxo1-C/Enhancer-binding Protein α Transcriptional Complex

Qiao, L., & Shao, J. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m607215200 · Cited by 378 · see citing works

Angiogenesis Inhibitor, TNP-470, Prevents Diet-Induced and Genetic Obesity in Mice

Bråkenhielm, E., Cao, R., Gao, B., Angelin, B., Cannon, B., Parini, P., & Cao, Y. (2004) · Circulation Research · doi:10.1161/01.res.0000132745.76882.70 · Cited by 326 · see citing works

Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance

Elias, I., Franckhauser, S., Ferré, T., Vilà, L., Tafuro, S., MUÑOZ, S. A., Roca, C., Ramos, D., Pujol, A., Riu, E., et al. (2012) · Diabetes · doi:10.2337/db11-0832 · Cited by 320 · see citing works

The immune cells in adipose tissue

Ferrante, A. W. (2013) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12154 · Cited by 306 · see citing works

SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aortic Endothelial Cells

Zu, Y., Liu, L., Lee, M. Y. K., Xu, C., Liang, Y., Man, R. Y., Vanhoutte, P. M., & Wang, Y. (2010) · Circulation Research · doi:10.1161/circresaha.109.215483 · Cited by 303 · see citing works

Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis

Zhang, G., Panigrahy, D., Mahakian, L. M., Yang, J., Liu, J., Lee, K. S. S., Wettersten, H. I., Ulu, A., Hu, X., Tam, S. M., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1304321110 · Cited by 292 · see citing works

Adipose tissue endothelial cells from obese human subjects: differences among depots in angiogenic, metabolic, and inflammatory gene expression and cellular senescence

Villaret, A., Galitzky, J., Decaunes, P., Estève, D., Marques, M.-A., Sengenès, C., Chiotasso, P., Tchkonia, T., Lafontan, M., Kirkland, J. L., et al. (2010) · Diabetes · doi:10.2337/db10-0398 · Cited by 282 · see citing works

The Sirtuin family: therapeutic targets to treat diseases of aging

Milne, J. C., & Denu, J. M. (2008) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2008.01.019 · Cited by 271 · see citing works

Omega-3 Polyunsaturated Fatty Acids Antagonize Macrophage Inflammation via Activation of AMPK/SIRT1 Pathway

Xue, B., Yang, Z., Wang, X., & Shi, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0045990 · Cited by 179 · see citing works

Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects With Insulin Resistance

Spencer, M. L., Finlin, B. S., Ünal, R., Zhu, B., Morris, A. J., Shipp, L. R., Lee, J. D., Walton, R. G., Adu, A. K., Erfani, R. A., et al. (2013) · Diabetes · doi:10.2337/db12-1042 · Cited by 179 · see citing works

Metabolic Signatures of Human Adipose Tissue Hypoxia in Obesity

Hodson, L., Humphreys, S. M., Karpe, F., & Frayn, K. N. (2012) · Diabetes · doi:10.2337/db12-1032 · Cited by 134 · see citing works

Angiogenesis Associated With Visceral and Subcutaneous Adipose Tissue in Severe Human Obesity

Ledoux, S., Quéguiner, I., Msika, S., Caldérari, S., Rufat, P., Gasc, J., Corvol, P. L., & Larger, É. (2008) · Diabetes · doi:10.2337/db07-1812 · Cited by 126 · see citing works

Modulation of angiogenesis by omega-3 polyunsaturated fatty acids is mediated by cyclooxygenases.

Szymczak, M., Murray, M., & Petrovic, N. (2008) · Blood · doi:10.1182/blood-2007-08-109934 · Cited by 121 · see citing works

Docosahexaenoic acid increases cellular adiponectin mRNA and secreted adiponectin protein, as well as PPARγ mRNA, in 3T3-L1 adipocytes

Oster, R. T., Tishinsky, J. M., Yuan, Z., & Robinson, L. E. (2010) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h10-076 · Cited by 115 · see citing works

Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistance

Wang, J., Badeanlou, L., Bielawski, J., Ciaraldi, T. P., & Samad, F. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00549.2013 · Cited by 101 · see citing works

Blockade of VEGFR2 and Not VEGFR1 Can Limit Diet-Induced Fat Tissue Expansion: Role of Local versus Bone Marrow-Derived Endothelial Cells

Tam, J., Duda, D. G., Perentes, J. Y., Quadri, R. S., Fukumura, D., & Jain, R. K. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004974 · Cited by 99 · see citing works

Identification of the Serine 307 of LKB1 as a Novel Phosphorylation Site Essential for Its Nucleocytoplasmic Transport and Endothelial Cell Angiogenesis

Xie, Z., Dong, Y., Zhang, J., Scholz, R., Neumann, D., & Zou, M. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01417-08 · Cited by 98 · see citing works

Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice

Michailidou, Z., Turban, S., Miller, E., Zou, X., Schrader, J., Ratcliffe, P. J., Hadoke, P. W. F., Walker, B. R., Iredale, J. P., Morton, N. M., et al. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.259325 · Cited by 93 · see citing works

PAI-1 and diabetes: a journey from the bench to the bedside

Schneider, D. J., & Sobel, B. E. (2012) · Diabetes Care · doi:10.2337/dc12-0638 · Cited by 78 · see citing works

Intestinal and Systemic Inflammatory Responses Are Positively Associated with Sulfidogenic Bacteria Abundance in High-Fat–Fed Male C57BL/6J Mice

Shen, W., Wolf, P. G., Carbonero, F. G., Wei, Z., Reid, T., Gaskins, H. R., & McIntosh, M. (2014) · Journal of Nutrition · doi:10.3945/jn.114.194332 · Cited by 76 · see citing works

Resistance to Obesity by Repression of VEGF Gene Expression through Induction of Brown-Like Adipocyte Differentiation

Lü, X., Ji, Y., Zhang, L., Zhang, Y., Zhang, S., An, Y., Liu, P., & Zheng, Y. (2012) · Endocrinology · doi:10.1210/en.2012-1151 · Cited by 70 · see citing works

Docosahexaenoic Acid Decreases Pro-Inflammatory Mediators in an In Vitro Murine Adipocyte Macrophage Co-Culture Model

Boer, A. A. D., Monk, J. M., & Robinson, L. E. (2014) · PLoS ONE · doi:10.1371/journal.pone.0085037 · Cited by 69 · see citing works

Identification of BMP and Activin Membrane-Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors

Luo, X. L., Hutley, L. J., Webster, J. A., Kim, Y., Liu, D., Newell, F., Widberg, C., Bachmann, A. W., Turner, N. A., Schmitz‐Peiffer, C., et al. (2011) · Diabetes · doi:10.2337/db11-0998 · Cited by 66 · see citing works

Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses

Yoon, H., Shin, S.-H., Shin, D. H., Chun, Y., & Park, J. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.01.001 · Cited by 65 · see citing works

Angiogenic Deficiency and Adipose Tissue Dysfunction Are Associated with Macrophage Malfunction in SIRT1−/− Mice

Xu, F. L., Burk, D. H., Gao, Z., Yin, J., Zhang, X., Weng, J., & Ye, J. (2012) · Endocrinology · doi:10.1210/en.2011-1667 · Cited by 64 · see citing works

Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells

Kim, H. J., Vosseler, C. A., Weber, P. C., & Erl, W. (2005) · Journal of Cellular Physiology · doi:10.1002/jcp.20351 · Cited by 61 · see citing works

Modulation of age-related insulin sensitivity by VEGF-dependent vascular plasticity in adipose tissues

Honek, J., Seki, T., Iwamoto, H., Fischer, C., Li, J., Lim, S., Samani, N. J., Zang, J., & Cao, Y. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1415825111 · Cited by 60 · see citing works

The Role of SIRT1 on Angiogenic and Odontogenic Potential in Human Dental Pulp Cells

Kim, J.-J., Kim, S., Kim, Y.-S., Kim, S., Park, S., & Kim, E.-C. (2012) · Journal of Endodontics · doi:10.1016/j.joen.2012.04.006 · Cited by 46 · see citing works

Resveratrol suppresses the STAT3 signaling pathway and inhibits proliferation of high glucose-exposed HepG2 cells partly through SIRT1

LI, Y., Zhu, W., LI, J., Liu, M., & WEI, M. (2013) · Oncology Reports · doi:10.3892/or.2013.2748 · Cited by 44 · see citing works

Immunometabolic role of long‐chain omega‐3 fatty acids in obesity‐induced inflammation

Flock, M. R., Rogers, C. J., Prabhu, K. S., & Kris‐Etherton, P. M. (2013) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2414 · Cited by 40 · see citing works

Docosahexaenoic Acid Inhibits Vascular Endothelial Growth Factor (VEGF)-Induced Cell Migration via the GPR120/PP2A/ERK1/2/eNOS Signaling Pathway in Human Umbilical Vein Endothelial Cells

Chao, C., Lii, C., Ye, S.-Y., Li, C., Lu, C., Lin, A., Liu, K., & Chen, H. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf5007165 · Cited by 38 · see citing works

PPARγ agonists in type 2 diabetes: how far have we come in ‘preventing the inevitable’? A review of the metabolic effects of rosiglitazone

Zinman, B. (2001) · Diabetes Obesity and Metabolism · doi:10.1046/j.1463-1326.2001.00033.x · Cited by 37 · see citing works

Benefits of healthy adipose tissue in the treatment of diabetes

Gunawardana, S. C. (2014) · World Journal of Diabetes · doi:10.4239/wjd.v5.i4.420 · Cited by 24 · see citing works

Docosahexaenoic acid inhibits insulin-induced activation of sterol regulatory-element binding protein 1 and cyclooxygenase-2 expression through upregulation of SIRT1 in human colon epithelial cells

Song, N., Na, H., Baek, J., & Surh, Y. (2014) · Biochemical Pharmacology · doi:10.1016/j.bcp.2014.08.030 · Cited by 20 · see citing works

Connexin 43 and metabolic effect of fatty acids in stressed endothelial cells

Kieć‐Wilk, B., Czech, U., Janczarska, K., Knapp, A., Góralska, J., Ciałowicz, U., Malecki, M. T., & Dembinska-Kiec, A. (2011) · Genes & Nutrition · doi:10.1007/s12263-011-0247-5 · Cited by 12 · see citing works

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis.

Crewe, C., An, Y. A., & Scherer, P. E. (2017) · Journal of Clinical Investigation · doi:10.1172/jci88883 · Cited by 732 · see citing works

“Cell Membrane Theory of Senescence” and the Role of Bioactive Lipids in Aging, and Aging Associated Diseases and Their Therapeutic Implications

Das, U. N. (2021) · Biomolecules · doi:10.3390/biom11020241 · Cited by 142 · see citing works

Insulin-sensitizing effects of omega-3 fatty acids: lost in translation?

Lalia, A., & Lanza, I. (2016) · Nutrients · doi:10.3390/nu8060329 · Cited by 141 · see citing works

Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis

An, Y., Sun, K., Joffin, N., Zhang, F., Deng, Y., Donzé, O., Kusminski, C. M., & Scherer, P. E. (2017) · eLife · doi:10.7554/elife.24071 · Cited by 77 · see citing works

Oral Administration of Linoleic Acid Induces New Vessel Formation and Improves Skin Wound Healing in Diabetic Rats

Rodrigues, H. G., Vinolo, M. A. R., Sato, F. T., Magdalon, J., Kühl, C. M. C., Yamagata, A. S., Pessoa, A. F. M., Malheiros, G., dos Santos, M. F., Lima, C., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0165115 · Cited by 69 · see citing works

Nutritional approaches for managing obesity-associated metabolic diseases

Botchlett, R. E., Woo, S., Liu, M., Pei, Y., Guo, X., Li, H., & Wu, C. (2017) · Journal of Endocrinology · doi:10.1530/joe-16-0580 · Cited by 62 · see citing works

The metabolic dysfunction of white adipose tissue induced in mice by a high-fat diet is abrogated by co-administration of docosahexaenoic acid and hydroxytyrosol

Illesca, P., Valenzuela, R., Espinosa, A., Echeverría, F., Soto-Alarcón, S. A., Ortíz, M., Campos, C., Vargas, R., & Videla, L. A. (2020) · Food & Function · doi:10.1039/d0fo01790f · Cited by 52 · see citing works

Cerasus humilis Cherry Polyphenol Reduces High-Fat Diet-Induced Obesity in C57BL/6 Mice by Mitigating Fat Deposition, Inflammation, and Oxidation

Liu, S., Chang, X., Yu, J., & Xu, W. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c01617 · Cited by 48 · see citing works

Docosahexaenoic acid enhances hippocampal insulin sensitivity to promote cognitive function of aged rats on a high-fat diet

Xu, J., Ni, B., Ma, C., Rong, S., Gao, H. Y., Zhang, L., Xia, X., Huang, Q., Deng, Q., & Huang, F. (2022) · Journal of Advanced Research · doi:10.1016/j.jare.2022.04.015 · Cited by 38 · see citing works

PINK1 signaling in mitochondrial homeostasis and in aging (Review)

Kitagishi, Y., Nakano, N., Ogino, M., Ichimura‐Shimizu, M., Minami, A., & Matsuda, S. (2016) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2016.2827 · Cited by 38 · see citing works

Therapeutic Potentials of Microalgae and Their Bioactive Compounds on Diabetes Mellitus

Tamel Selvan, K., Goon, J. A., Makpol, S., & Tan, J. K. (2023) · Marine Drugs · doi:10.3390/md21090462 · Cited by 32 · see citing works

Omega 3 rich diet modulates energy metabolism via GPR120-Nrf2 crosstalk in a novel antioxidant mouse model

Amos, D., Cook, C. R., & Santanam, N. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2019.01.002 · Cited by 28 · see citing works

Maternal eicosapentaenoic acid feeding promotes placental angiogenesis through a Sirtuin-1 independent inflammatory pathway

Peng, J., Zhou, Y., Zhang, H., Wu, Y., Cai, A., Mao, X., Deng, Z., Yang, Y., Song, T., Xiong, J., et al. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2018.11.003 · Cited by 27 · see citing works

DHA Protects Against Hepatic Steatosis by Activating Sirt1 in a High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model

Luo, X. M., He, Z., Sun, X., Gu, X., Zhang, W., Gao, J., Li, X., Jia, R., Wei, J., Yu, Y., et al. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s232279 · Cited by 25 · see citing works

A PUFA-rich diet improves fat oxidation following saturated fat-rich meal

Stevenson, J. L., Miller, M. K., Skillman, H. E., Paton, C. M., & Cooper, J. A. (2016) · European Journal of Nutrition · doi:10.1007/s00394-016-1226-9 · Cited by 23 · see citing works

Cold Exposure Differentially Stimulates Angiogenesis in BAT and WAT of Mice: Implication in Adrenergic Activation

Luo, X. M., Jia, R., Luo, X., Wang, G., Zhang, Q., Qiao, H., Wang, N., & Yan, J. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000478680 · Cited by 23 · see citing works

Associations between omega-3 fatty acids and insulin resistance and body composition in women with polycystic ovary syndrome

Lu, L., Li, X., Lv, L., Xu, Y., Wu, B., & Huang, C. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1016943 · Cited by 22 · see citing works

Docosahexaenoic acid-enriched phospholipids and eicosapentaenoic acid-enriched phospholipids inhibit tumor necrosis factor-alpha-induced lipolysis in 3T3-L1 adipocytes by activating sirtuin 1 pathways

Yang, Y., Hao, Y., Liu, X., Gao, X., Wang, B., Takahashi, K., & Du, L. (2021) · Food & Function · doi:10.1039/d1fo00157d · Cited by 21 · see citing works

PGRN exerts inflammatory effects via SIRT1-NF-κB in adipose insulin resistance

Li, H., Zhang, Z., Feng, D., Xu, L., Li, F., Liu, J., Jin, X., Qian, Z., Kang, X., & Sun, H. (2020) · Journal of Molecular Endocrinology · doi:10.1530/jme-19-0211 · Cited by 20 · see citing works

Maternal Eicosapentaenoic Acid Feeding Decreases Placental Lipid Deposition and Improves the Homeostasis of Oxidative Stress Through a Sirtuin‐1 (SIRT1) Independent Manner

Peng, J., Xiong, J., Cui, C., Huang, N., Zhang, H., Wu, X., Yang, Y., Zhou, Y., Wei, H., & Peng, J. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900343 · Cited by 17 · see citing works

Does dietary fat affect advanced glycation end products and their receptors? A systematic review of clinical trials

Mendes, N. P., Ribeiro, P. V. D. M., & Alfenas, R. D. C. G. (2021) · Nutrition Reviews · doi:10.1093/nutrit/nuab095 · Cited by 12 · see citing works

Dietary fatty acids as nutritional modulators of sirtuins: a systematic review

Caldas, A. P. S., Rocha, D. M. U. P., Bressan, J., & Hermsdorff, H. H. M. (2020) · Nutrition Reviews · doi:10.1093/nutrit/nuaa007 · Cited by 11 · see citing works

Omega-3 polyunsaturated fatty acids promote SNAREs mediated GLUT4 vesicle docking and fusion

Zhang, Y., He, L., Chen, X., Shentu, P., Xu, Y., & Jiao, J. (2021) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2021.108912 · Cited by 10 · see citing works

Anti-diabetic Effects of Macronutrients via Modulation of Angiogenesis: A Comprehensive Review on Carbohydrates and Proteins

Khosravifar, M., Sajadimajd, S., & Bahrami, G. (2022) · Current Molecular Medicine · doi:10.2174/1566524022666220321125548 · Cited by 7 · see citing works

Resveratrol reversed ambient particulate matter exposure-perturbed oscillations of hepatic glucose metabolism by regulating SIRT1 in mice

Jiang, J., Gu, Y., Ding, S., Zhang, G., & Ding, J. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-24434-2 · Cited by 7 · see citing works

Differential Modulation by Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) of Mesenteric Fat and Macrophages and T Cells in Adipose Tissue of Obese fa/fa Zucker Rats

Hong, L., Zahradka, P. C., & Taylor, C. G. (2024) · Nutrients · doi:10.3390/nu16091311 · Cited by 6 · see citing works

Anti-Diabetic Effects of Isolated Lipids from Natural Sources through Modulation of Angiogenesis

Bahrami, G., Sajadimajd, S., & Khosravifar, M. (2021) · Current Molecular Pharmacology · doi:10.2174/1874467214666210902121337 · Cited by 4 · see citing works

Long-chain fatty acids rewire macrophage polarization through metabolic reprogramming: mechanisms and disease implications

He, C., Liu, Y., Lv, K., An, Z., Xue, C., & Dong, N. (2026) · International Immunopharmacology · doi:10.1016/j.intimp.2026.116876 · Cited by 2 · see citing works

Naturalne i syntetyczne modulatory aktywności sirtuin

Wiercińska, M., & Rosołowska‐Huszcz, D. (2017) · Cited by 2 · see citing works

Omega-3 Fatty Acids and Alzheimer’s Disease: Toward a New Understanding of Neuroprotective Mechanisms and Intervention Strategies

Galizzi, G. (2026) · Marine Drugs · doi:10.3390/md24070224 · Cited by 1 · see citing works

DHA Protects Against Hepatic Steatosis by Activating Sirt1 in a High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model

Luo, X. M., He, Z., Sun, X., Gu, X., Zhang, W., Gao, J., Li, X., Jia, R., Wei, J., Yu, Y., et al. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s232279 · Cited by 25 · see citing works

Docosahexaenoic acid attenuates macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA

Oliver, E., McGillicuddy, F. C., Harford, K. A., Reynolds, C. M., Phillips, C. M., Ferguson, J. F., & Roche, H. M. (2011) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2011.06.014 · Cited by 139 · see citing works

Foreword

Clayton, R. N. (1983) · Clinics in Endocrinology and Metabolism · doi:10.1016/s0300-595x(83)80024-3

Docosahexaenoic Acid Inhibits White Adipogenesis and Enhances Mitochondrial Biogenesis through SIRT1 and Hh Signaling

Chen, Y., Kuo, W., Chang, Y., Huang, C., Liu, H., Cheng, Y., Mersmann, H. J., & Ding, S. (2015) · The FASEB Journal · doi:10.1096/fasebj.29.1_supplement.995.11 · Cited by 3 · see citing works

Resolvin D1 and Its Precursor Docosahexaenoic Acid Promote Resolution of Adipose Tissue Inflammation by Eliciting Macrophage Polarization toward an M2-Like Phenotype

Titos, E., Rius, B., González-Périz, A., López-Vicario, C., Morán-Salvador, E., Martínez-Clemente, M., Arroyo, V., & Clària, J. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1100225 · Cited by 412 · see citing works