Insulin-sensitizing effects of omega-3 fatty acids: lost in translation?

Role of Insulin Resistance in Human Disease

Reaven, G. M. (1988) · Diabetes · doi:10.2337/diab.37.12.1595 · Cited by 12,154 · see citing works

Inflammation and insulin resistance

Shoelson, S. E. (2006) · Journal of Clinical Investigation · doi:10.1172/jci29069 · Cited by 4,769 · see citing works

Lipid rafts as a membrane-organizing principle

Lingwood, D., & Simons, K. (2010) · Science · doi:10.1126/science.1174621 · Cited by 4,417 · see citing works

Evidence for the Formation of Symmetric and Asymmetric DLPC-DAPC Lipid Bilayer Domains

Ritter, M., Schmidt, S., Jakab, M., Paulmichl, M., & Henderson, R. M. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350122 · Cited by 3,923 · see citing works

Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease

Kris-Etherton, P. M., Harris, W. S., & Appel, L. J. (2002) · Circulation · doi:10.1161/01.cir.0000038493.65177.94 · Cited by 3,707 · see citing works

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism

Desvergne, B., & Wahli, W. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.5.0380 · Cited by 3,079 · see citing works

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

Oh, D. Y., Talukdar, S., Bae, E. J., Imamura, T., Morinaga, H., Fan, W., Li, P., Lu, W. J., Watkins, S. M., & Olefsky, J. M. (2010) · Cell · doi:10.1016/j.cell.2010.07.041 · Cited by 2,428 · see citing works

Mechanisms for Insulin Resistance: Common Threads and Missing Links

Samuel, V. T., & Shulman, G. I. (2012) · Cell · doi:10.1016/j.cell.2012.02.017 · Cited by 2,294 · see citing works

Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes

Petersen, K. F., Dufour, S., Befroy, D., Garcia, R., & Shulman, G. I. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa031314 · Cited by 2,193 · see citing works

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

Petersen, K. F., Befroy, D., Dufour, S., Dziura, J., Ariyan, C., Rothman, D. L., DiPietro, L., Cline, G. W., & Shulman, G. I. (2003) · Science · doi:10.1126/science.1082889 · Cited by 2,107 · see citing works

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

Anderson, E. J., Lustig, M. E., Boyle, K. E., Woodlief, T. L., Kane, D. A., Lin, C.-T., Price, J. W., Kang, L., Rabinovitch, P. S., Szeto, H. H., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci37048 · Cited by 1,253 · see citing works

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism

Desvergne, B. (1999) · Endocrine Reviews · doi:10.1210/er.20.5.649 · Cited by 1,251 · see citing works

Resolution Phase of Inflammation: Novel Endogenous Anti-Inflammatory and Proresolving Lipid Mediators and Pathways

Serhan, C. N. (2006) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141647 · Cited by 997 · see citing works

Influence of Dietary Fat Composition on Development of Insulin Resistance in Rats: Relationship to Muscle Triglyceride and ω-3 Fatty Acids in Muscle Phospholipid

Storlien, L. H., Jenkins, A. B., Chisholm, D. J., Pascoe, W. S., Khouri, S., & Kraegen, E. W. (1991) · Diabetes · doi:10.2337/diab.40.2.280 · Cited by 967 · see citing works

Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms

Larsson, S. C., Kumlin, M., Ingelman-Sundberg, M., & Wolk, A. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.6.935 · Cited by 950 · see citing works

High-Density Lipoprotein Subfractions - What the Clinicians Need to Know

Pirillo, A., Norata, G. D., & Catapano, A. L. (2013) · Cardiology · doi:10.1159/000346463 · Cited by 749 · see citing works

Protein carbamylation links inflammation, smoking, uremia and atherogenesis

Wang, Z., Nicholls, S. J., Rodríguez, E. R., Kummu, O., Hörkkö, S., Barnard, J., Reynolds, W. F., Topol, E. J., DiDonato, J. A., & Hazen, S. L. (2007) · Nature Medicine · doi:10.1038/nm1637 · Cited by 706 · see citing works

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis

Spite, M., Norling, L. V., Summers, L., Yang, R., Cooper, D., Petasis, N. A., Flower, R. J., Perretti, M., & Serhan, C. N. (2009) · Nature · doi:10.1038/nature08541 · Cited by 695 · see citing works

Increased dietary intake of ω-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis

Connor, K. M., SanGiovanni, J. P., Löfqvist, C., Aderman, C. M., Chen, J., Higuchi, A., Hong, S., Pravda, E. A., Majchrzak, S. F., Carper, D. A., et al. (2007) · Nature Medicine · doi:10.1038/nm1591 · Cited by 687 · see citing works

Ceramide Content Is Increased in Skeletal Muscle From Obese Insulin-Resistant Humans

Adams, J. M., Pratipanawatr, T., Berria, R., Wang, E. L., DeFronzo, R. A., Sullards, M. C., & Mandarino, L. J. (2004) · Diabetes · doi:10.2337/diabetes.53.1.25 · Cited by 670 · see citing works

Fish Oil Prevents Insulin Resistance Induced by High-Fat Feeding in Rats

Storlien, L. H., Kraegen, E. W., Chisholm, D. J., Ford, G. L., Bruce, D. G., & Pascoe, W. S. (1987) · Science · doi:10.1126/science.3303333 · Cited by 650 · see citing works

Glucose Intolerance and Aging: Evidence for Tissue Insensitivity to Insulin

DeFronzo, R. A. (1979) · Diabetes · doi:10.2337/diab.28.12.1095 · Cited by 595 · see citing works

Endurance Exercise as a Countermeasure for Aging

Lanza, I. R., Short, D. K., Short, K. R., Raghavakaimal, S., Basu, R., Joyner, M. J., McConnell, J. P., & Nair, K. S. (2008) · Diabetes · doi:10.2337/db08-0349 · Cited by 582 · see citing works

n–3 Fatty Acids in Cardiovascular Disease

Caterina, R. D. (2011) · New England Journal of Medicine · doi:10.1056/nejmra1008153 · Cited by 568 · see citing works

Subdivisions of subcutaneous abdominal adipose tissue and insulin resistance

Kelley, D. E., Thaete, F. L., Troost, F., Huwe, T., & Goodpaster, B. H. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.278.5.e941 · Cited by 538 · see citing works

Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

Spite, M., Clària, J., & Serhan, C. N. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2013.10.006 · Cited by 464 · see citing works

Racial Differences in the Relation between Blood Pressure and Insulin Resistance

Saad, M. F., Lillioja, S., Nyomba, B. L., Castillo, C., Ferraro, R., De Gregorio, M., Ravussin, E., Knowler, W. C., Bennett, P. H., Howard, B. V., et al. (1991) · New England Journal of Medicine · doi:10.1056/nejm199103143241105 · Cited by 421 · see citing works

M <scp>USCLE</scp> T <scp>RIGLYCERIDE AND</scp> I <scp>NSULIN</scp> R <scp>ESISTANCE</scp>

Kelley, D. E., Goodpaster, B. H., & Storlien, L. (2002) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.22.010402.102912 · Cited by 364 · see citing works

Effects of dietary polyunsaturated n-3 fatty acids on dyslipidemia and insulin resistance in rodents and humans. A review

Lombardo, Y. B., & Chicco, A. G. (2005) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2005.08.002 · Cited by 359 · see citing works

Association of Marine Omega-3 Fatty Acid Levels With Telomeric Aging in Patients With Coronary Heart Disease

Farzaneh‐Far, R. (2010) · JAMA · doi:10.1001/jama.2009.2008 · Cited by 354 · see citing works

Effect of dietary fish oil on body fat mass and basal fat oxidation in healthy adults

Couet, C., Delarue, J., Ritz, P., Antoine, J.-M., & Lamisse, F. (1997) · International Journal of Obesity · doi:10.1038/sj.ijo.0800451 · Cited by 344 · see citing works

Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids.

Kidd, P. M. (2007) · PubMed · Cited by 340 · see citing works

Omega-3 fatty acids and incident type 2 diabetes: A systematic review and meta-analysis

Wu, J. H. Y., Micha, R., Imamura, F., Pan, A., Biggs, M. L., Ajaz, O., Djousse, L., B. Hu, F., & Mozaffarian, D. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512001602 · Cited by 340 · see citing works

Resolution phase lipid mediators of inflammation: agonists of resolution

Serhan, C. N., & Chiang, N. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.05.012 · Cited by 332 · see citing works

Omega‐3 Dietary Supplements and the Risk of Cardiovascular Events: A Systematic Review

Marik, P. E., & Varon, J. (2009) · Clinical Cardiology · doi:10.1002/clc.20604 · Cited by 328 · see citing works

Treatment for 2 mo with n 3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: A randomized controlled study

Kabir, M., Skurnik, G., Naour, N., Pechtner, V., Meugnier, E., Rome, S., Quignard-Boulangé, A., Vidal, H., Slama, G., Clément, K., et al. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.5.1670 · Cited by 316 · see citing works

(n-3) Fatty Acids Alleviate Adipose Tissue Inflammation and Insulin Resistance: Mechanistic Insights

Kalupahana, N. S., Claycombe, K. J., & Moustaid-Moussa, N. (2011) · Advances in Nutrition · doi:10.3945/an.111.000505 · Cited by 305 · see citing works

Effect of Probiotic (VSL#3) and Omega-3 on Lipid Profile, Insulin Sensitivity, Inflammatory Markers, and Gut Colonization in Overweight Adults: A Randomized, Controlled Trial

Rajkumar, H., Mahmood, N., Kumar, M., Varikuti, S. R., Challa, H. R., & Myakala, S. P. (2014) · Mediators of Inflammation · doi:10.1155/2014/348959 · Cited by 301 · see citing works

Eicosapentaenoic Acid Prevents and Reverses Insulin Resistance in High-Fat Diet-Induced Obese Mice via Modulation of Adipose Tissue Inflammation1–3

Kalupahana, N. S., Claycombe, K., Newman, S. J., Stewart, T. P., Siriwardhana, N., Matthan, N. R., Lichtenstein, A. H., & Moustaïd‐Moussa, N. (2010) · Journal of Nutrition · doi:10.3945/jn.110.125732 · Cited by 301 · see citing works

Age, Obesity, and Sex Effects on Insulin Sensitivity and Skeletal Muscle Mitochondrial Function

Karakelides, H., Irving, B. A., Short, K. R., O'Brien, P., & Nair, K. S. (2010) · Diabetes · doi:10.2337/db09-0591 · Cited by 293 · see citing works

Omega-3 polyunsaturated fatty acids (PUFA) for type 2 diabetes mellitus

Hartweg, J., Perera, R., Montori, V. M., Dinneen, S. F., Neil, A. H., & Farmer, A. J. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003205.pub2 · Cited by 282 · see citing works

Dose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia

Skulas-Ray, A. C., Kris-Etherton, P. M., Harris, W. S., Vanden Heuvel, J. P., Wagner, P. R., & West, S. G. (2011) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.003871 · Cited by 280 · see citing works

Effect of Oral Eicosapentaenoic Acid on Weight Loss in Patients With Pancreatic Cancer

Wigmore, S. J., Barber, M. D., Ross, J. A., Tisdale, M. J., & Fearon, K. C. H. (2000) · Nutrition and Cancer · doi:10.1207/s15327914nc3602_6 · Cited by 275 · see citing works

Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle

Ellis, B. A., Poynten, A., Lowy, A. J., Furler, S. M., Chisholm, D. J., Kraegen, E. W., & Cooney, G. J. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.279.3.e554 · Cited by 273 · see citing works

1,2-Diacylglycerol and ceramide levels in insulin-resistant tissues of the rat in vivo.

Turinsky, J., O'Sullivan, D. M., & Bayly, B. P. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44844-7 · Cited by 269 · see citing works

Randomized trial of weight-loss-diets for young adults varying in fish and fish oil content

Þórsdóttir, I., Tómasson, H., Gunnarsdóttir, I., Gisladottir, E. U., Kiely, M. E., Parra, M. D., Bandarra, N. M., Schaafsma, G., & Martínez, J. A. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803643 · Cited by 261 · see citing works

Fish oil supplementation in type 2 diabetes: a quantitative systematic review.

Montori, V. M., Farmer, A. A., Wollan, P. C., & Dinneen, S. F. (2000) · Diabetes Care · doi:10.2337/diacare.23.9.1407 · Cited by 241 · see citing works

Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors

Hill, A. M., Buckley, J. D., Murphy, K. J., & Howe, P. R. C. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.5.1267 · Cited by 237 · see citing works

n-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a Peroxisome Proliferator–Activated Receptor-α–Dependent Manner

Neschen, S., Morino, K., Dong, J., Wang-Fischer, Y., Cline, G. W., Romanelli, A. J., Rossbacher, J. C., Moore, I. K., Regittnig, W., Muñoz, D. S., et al. (2007) · Diabetes · doi:10.2337/db06-1206 · Cited by 233 · see citing works

Glucose tolerance in young and older athletes and sedentary men

Seals, D. R., Hagberg, J. M., Allen, W. K., Hurley, B. F., Dalsky, G. P., Ehsani, A. A., & Holloszy, J. O. (1984) · Journal of Applied Physiology · doi:10.1152/jappl.1984.56.6.1521 · Cited by 228 · see citing works

Additive benefits of long-chain n-3 polyunsaturated fatty acids and weight-loss in the management of cardiovascular disease risk in overweight hyperinsulinaemic women

Krebs, J. D., Browning, L. M., McLean, N., Rothwell, J. L., Mishra, G. D., Moore, C. S., & Jebb, S. A. (2006) · International Journal of Obesity · doi:10.1038/sj.ijo.0803309 · Cited by 221 · see citing works

Fish Consumption, Dietary Long-Chain n-3 Fatty Acids, and Risk of Type 2 Diabetes

Wallin, A., Giuseppe, D. D., Orsini, N., Patel, P. S., Forouhi, N. G., & Wolk, A. (2012) · Diabetes Care · doi:10.2337/dc11-1631 · Cited by 220 · see citing works

Increased skeletal muscle ceramide level in men at risk of developing type 2 diabetes

Strączkowski, M., Kowalska, I., Baranowski, M., Nikołajuk, A., Otziomek, E., Zabielski, P., Adamska, A., Blachnio, A., Górski, J., & Górska, M. (2007) · Diabetologia · doi:10.1007/s00125-007-0781-2 · Cited by 219 · see citing works

Effects of altering the ratio of dietary n−6 to n−3 fatty acids on insulin sensitivity, lipoprotein size, and postprandial lipemia in men and postmenopausal women aged 45–70 y: the OPTILIP Study

Griffin, M., Sanders, T. A. B., Davies, I. G., Morgan, L., Millward, D. J., Lewis, F., Slaughter, S. L., Cooper, J. A., Miller, G. J., & Griffin, B. A. (2006) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.6.1290 · Cited by 189 · see citing works

Transgenic restoration of long-chain n-3 fatty acids in insulin target tissues improves resolution capacity and alleviates obesity-linked inflammation and insulin resistance in high-fat-fed mice

White, P. J., Arita, M., Taguchi, R., Kang, J. X., & Marette, A. (2010) · Diabetes · doi:10.2337/db10-0054 · Cited by 185 · see citing works

The Effect of n-3 Fatty Acids on Glucose Homeostasis and Insulin Sensitivity

Flachs, P., Rossmeisl, M., & Kopecký, J. (2014) · Physiological Research · doi:10.33549/physiolres.932715 · Cited by 183 · see citing works

n -3 Polyunsaturated fatty acids prevent the defect of insulin receptor signaling in muscle

Taouis, M., Dagou, C., Ster, C., Durand, G., Pinault, M., & Delarue, J. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00320.2001 · Cited by 181 · see citing works

Omega-3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle

Herbst, E. A. F., Paglialunga, S., Gerling, C., Whitfield, J., Mukai, K., Chabowski, A., Heigenhauser, G. J. F., Spriet, L. L., & Holloway, G. P. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2013.267336 · Cited by 179 · see citing works

Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects With Insulin Resistance

Spencer, M. L., Finlin, B. S., Ünal, R., Zhu, B., Morris, A. J., Shipp, L. R., Lee, J. D., Walton, R. G., Adu, A. K., Erfani, R. A., et al. (2013) · Diabetes · doi:10.2337/db12-1042 · Cited by 179 · see citing works

Effects of ALA, EPA and DHA in high-carbohydrate, high-fat diet-induced metabolic syndrome in rats

Poudyal, H., Panchal, S. K., Ward, L. C., & Brown, L. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2012.07.014 · Cited by 170 · see citing works

Docosahexaenoic and eicosapentaenoic acids segregate differently between raft and nonraft domains

Williams, J. A., Batten, S. E., Harris, M., Rockett, B. D., Shaikh, S. R., Stillwell, W., & Wassall, S. R. (2012) · Biophysical Journal · doi:10.1016/j.bpj.2012.06.016 · Cited by 168 · see citing works

Omega-3 polyunsaturated fatty acid and insulin sensitivity: A meta-analysis of randomized controlled trials

Akinkuolie, A. O., Ngwa, J. S., Meigs, J. B., & Djoussé, L. (2011) · Clinical Nutrition · doi:10.1016/j.clnu.2011.08.013 · Cited by 167 · see citing works

Long-Term Effects of Fish Oil on Insulin Resistance and Plasma Lipoproteins in NIDDM Patients With Hypertriglyceridemia

Rivellese, A. A., Maffettone, A., Iovine, C., Marino, L. D., Annuzzi, G., Mancini, M., & Riccardi, G. (1996) · Diabetes Care · doi:10.2337/diacare.19.11.1207 · Cited by 166 · see citing works

The impact of long chain <i>n</i> ‐3 polyunsaturated fatty acid supplementation on inflammation, insulin sensitivity and CVD risk in a group of overweight women with an inflammatory phenotype

Browning, L. M., Krebs, J. D., Moore, C. S., Mishra, G. D., O’Connell, M. A., & Jebb, S. A. (2007) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2006.00576.x · Cited by 162 · see citing works

A high ratio of dietary n-3/n-6 polyunsaturated fatty acids improves obesity-linked inflammation and insulin resistance through suppressing activation of TLR4 in SD rats

Liu, H.-Q., Qiu, Y. F., Mu, Y., Zhang, X.-J., Liu, L., Hou, X.-H., Zhang, L., Xu, X., Ji, A.-L., Cao, R., et al. (2013) · Nutrition Research · doi:10.1016/j.nutres.2013.07.004 · Cited by 160 · see citing works

Mediterranean Diet for Primary Prevention of Cardiovascular Disease

(2014) · New England Journal of Medicine · doi:10.1056/nejmx140016 · Cited by 158 · see citing works

Effects of n−3 fatty acids in subjects with type 2 diabetes: reduction of insulin sensitivity and time-dependent alteration from carbohydrate to fat oxidation

Mostad, I. L., Bjerve, K. S., Bjorgaas, M. R., Lydersen, S., & Grill, V. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.3.540 · Cited by 152 · cited 2× · see citing works

n-3 Fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet

Kuda, O., Jelenik, T., Jilkova, Z., Flachs, P., Rossmeisl, M., Hensler, M., Kazdova, L., Ogston, N., Baranowski, M., Gorski, J., et al. (2009) · Diabetologia · doi:10.1007/s00125-009-1305-z · Cited by 142 · see citing works

Trends in Hyperinsulinemia Among Nondiabetic Adults in the U.S.

Li, C., Ford, E. S., McGuire, L. C., Mokdad, A. H., Little, R. R., & Reaven, G. M. (2006) · Diabetes Care · doi:10.2337/dc06-0289 · Cited by 136 · see citing works

Influence of fish oil on skeletal muscle mitochondrial energetics and lipid metabolites during high-fat diet

Lanza, I. R., Blachnio-Zabielska, A., Johnson, M. L., Schimke, J. M., Jakaitis, D. R., Lebrasseur, N. K., Jensen, M. D., Sreekumaran Nair, K., & Zabielski, P. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00584.2012 · Cited by 135 · see citing works

Beneficial effects of long-chain n-3 fatty acids included in an energy-restricted diet on insulin resistance in overweight and obese European young adults

Ramel, A., Martínez, J. A., Kiely, M. E., Morais, G., Bandarra, N. M., & Þórsdóttir, I. (2008) · Diabetologia · doi:10.1007/s00125-008-1035-7 · Cited by 131 · see citing works

High Omega-3 Fat Intake Improves Insulin Sensitivity and Reduces CRP and IL6, but does not Affect Other Endocrine Axes in Healthy Older Adults

Tsitouras, P. D., Gucciardo, F., Salbe, A. D., Heward, C. B., & Harman, S. M. (2008) · Hormone and Metabolic Research · doi:10.1055/s-2008-1046759 · Cited by 131 · see citing works

Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis

White, P. J., St‐Pierre, P., Charbonneau, A., Mitchell, P. L., St-Amand, E., Marcotte, B., & Marette, A. (2014) · Nature Medicine · doi:10.1038/nm.3549 · Cited by 130 · see citing works

Mechanism by Which Caloric Restriction Improves Insulin Sensitivity in Sedentary Obese Adults

Johnson, M. L., Distelmaier, K., Lanza, I. R., Irving, B. A., Robinson, M. M., Konopka, A. R., Shulman, G. I., & Nair, K. S. (2016) · Diabetes · doi:10.2337/db15-0675 · Cited by 129 · see citing works

Eicosapentaenoic acid-enriched phospholipid ameliorates insulin resistance and lipid metabolism in diet-induced-obese mice

Liu, X., Xue, Y., Liu, C., Lou, Q., Wang, J., Yanagita, T., Xue, C., & Wang, Y. (2013) · Lipids in Health and Disease · doi:10.1186/1476-511x-12-109 · Cited by 128 · see citing works

Marine N-3 Polyunsaturated Fatty Acids Are Inversely Associated with Risk of Type 2 Diabetes in Asians: A Systematic Review and Meta-Analysis

Zheng, J.-S., Huang, T., Yang, J., Fu, Y.-Q., & Li, D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044525 · Cited by 126 · see citing works

n-6:n-3 PUFA ratio is involved in regulating lipid metabolism and inflammation in pigs

Duan, Y., Li, F., Li, L., Fan, J., Sun, X., & Yin, Y. (2013) · British Journal Of Nutrition · doi:10.1017/s0007114513002584 · Cited by 120 · see citing works

Omega-3 fatty acids improve glucose tolerance and components of the metabolic syndrome in Alaskan Eskimos: the Alaska Siberia project

Ebbesson, S. O. E., Risica, P. M., Ebbesson, L. O. E., Kennish, J. M., & Tejero, M. E. (2005) · International Journal of Circumpolar Health · doi:10.3402/ijch.v64i4.18016 · Cited by 120 · see citing works

Mediterranean diet for primary prevention of cardiovascular disease.

Mozaffarian, D. (2013) · PubMed · doi:10.1056/nejmc1306659 · Cited by 119 · see citing works

Differential effects of safflower oil versus fish oil feeding on insulin-stimulated glycogen synthesis, glycolysis, and pyruvate dehydrogenase flux in skeletal muscle: a 13C nuclear magnetic resonance study.

Jucker, B. M., Cline, G. W., Barucci, N., & Shulman, G. I. (1999) · Diabetes · doi:10.2337/diabetes.48.1.134 · Cited by 119 · see citing works

Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training

Konopka, A. R., Asante, A., Lanza, I. R., Robinson, M. M., Johnson, M. L., Dalla Man, C., Cobelli, C., Amols, M. H., Irving, B. A., & Nair, K. S. (2015) · Diabetes · doi:10.2337/db14-1701 · Cited by 112 · see citing works

The structure of DHA in phospholipid membranes

Gawrisch, K., Eldho, N. V., & Holte, L. L. (2003) · Lipids · doi:10.1007/s11745-003-1082-0 · Cited by 110 · see citing works

Fish Consumption and Incidence of Diabetes

Xun, P., & He, K. (2012) · Diabetes Care · doi:10.2337/dc11-1869 · Cited by 109 · see citing works

Endogenously Decreasing Tissue n-6/n-3 Fatty Acid Ratio Reduces Atherosclerotic Lesions in Apolipoprotein E –Deficient Mice by Inhibiting Systemic and Vascular Inflammation

Wan, J., Huang, L., Rong, R., Tan, R., Wang, J., & Kang, J. X. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.210054 · Cited by 107 · see citing works

Regulation of adipokine secretion by n -3 fatty acids

Moreno-Aliaga, M. J., Lorente‐Cebrián, S., & Martínez, J. A. (2010) · Proceedings of The Nutrition Society · doi:10.1017/s0029665110001801 · Cited by 105 · see citing works

Fish oil, insulin sensitivity, insulin secretion and glucose tolerance in healthy people: Is there any effect of fish oil supplementation in relation to the type of background diet and habitual dietary intake of n-6 and n-3 fatty acids?

Giacco, R., Cuomo, V., Vessby, B. O., Uusitupa, M. I. J., Hermansen, K., Meyer, B. J., Riccardi, G., & Rivellese, A. A. (2006) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2006.06.006 · Cited by 105 · see citing works

A Comparison of the Effects of n-3 Fatty Acids From Linseed Oil and Fish Oil in Well-Controlled Type II Diabetes

McManus, R. M., Jumpson, J., Finegood, D. T., Clandinin, M. T., & Ryan, E. A. (1996) · Diabetes Care · doi:10.2337/diacare.19.5.463 · Cited by 103 · see citing works

Intake of Fish and n-3 Fatty Acids and Future Risk of Metabolic Syndrome

Baik, I., Abbott, R. D., Curb, J. D., & Shin, C. (2010) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2010.04.013 · Cited by 101 · see citing works

Effects of N-3 PUFAs Supplementation on Insulin Resistance and Inflammatory Biomarkers in Hemodialysis Patients

Rašić-Milutinović, Z., Peruničić, G., Pljesa, S., Gluvic, Z. M., Sobajic, S. S., Djuricic, I. D., & Ristić, D. (2007) · Renal Failure · doi:10.1080/08860220601184092 · Cited by 100 · see citing works

A controlled study on the effects of n − 3 fatty acids on lipid and glucose metabolism in non-insulin-dependent diabetic patients

Annuzzi, G., Rivellese, A. A., Capaldo, B., Marino, L., Iovine, C., Marotta, G., & Riccardi, G. (1991) · Atherosclerosis · doi:10.1016/0021-9150(91)90233-s · Cited by 97 · see citing works

The effect of EPA and DHA on metabolic syndrome patients: a systematic review of randomised controlled trials

López‐Huertas, E. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512001572 · Cited by 93 · see citing works

AMP-activated protein kinase α2 subunit is required for the preservation of hepatic insulin sensitivity by n-3 polyunsaturated fatty acids

Jelenik, T., Rossmeisl, M., Kuda, O., Jilkova, Z. M., Medrikova, D., Kus, V., Hensler, M., Janovska, P., Miksik, I., Baranowski, M., et al. (2010) · Diabetes · doi:10.2337/db09-1716 · Cited by 88 · see citing works

Effects of omega-3 fatty acids supplementation on serum adiponectin levels and some metabolic risk factors in women with polycystic ovary syndrome.

Mohammadi, E., Rafraf, M., Farzadi, L., Jafarabadi, M. A., & Sabour, S. (2012) · PubMed · Cited by 84 · see citing works

Blood profiles, body fat and mood state in healthy subjects on different diets supplemented with Omega‐3 polyunsaturated fatty acids

Fontani, G., Corradeschi, F., Felici, A., Alfatti, F., Bugarini, R., Fiaschi, A. I., Cerretani, D., Montorfano, G., Rizzo, A. M., & Berra, B. (2005) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2005.01540.x · Cited by 81 · see citing works

Effects of fish oil on metabolic responses to oral fructose and glucose loads in healthy humans

Delarue, J., Couet, C., Cohen, R., Bréchot, J.-F., Antoine, J. M., & Lamisse, F. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.270.2.e353 · Cited by 80 · see citing works

Omega-3 index, obesity and insulin resistance in children

Burrows, T. L., Collins, C. E., & Garg, M. L. (2011) · International Journal of Pediatric Obesity · doi:10.3109/17477166.2010.549489 · Cited by 78 · see citing works

The nutritional and clinical significance of lipid rafts

Yaqoob, P., & Shaikh, S. R. (2010) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e328335725b · Cited by 76 · see citing works

Predictors of Whole-Body Insulin Sensitivity Across Ages and Adiposity in Adult Humans

Lalia, A. Z., Dasari, S., Johnson, M. L., Robinson, M. M., Konopka, A. R., Distelmaier, K., Port, J. D., Glavin, M., Esponda, R. R., Nair, K. S., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-2892 · Cited by 74 · see citing works

Effects of dietary n-3 fatty acids on hepatic and peripheral insulin sensitivity in insulin resistant humans

Lalia, A. Z., Johnson, M. L., Jensen, M. D., Hames, K. C., Port, J. D., & Lanza, I. R. (2015) · Diabetes Care · doi:10.2337/dc14-3101 · Cited by 73 · see citing works

Effects of n-3 PUFAs on postprandial variation of metalloproteinases, and inflammatory and insulin resistance parameters in dyslipidemic patients: Evaluation with euglycemic clamp and oral fat load

Derosa, G., Cicero, A. F. G., Fogari, E., D’Angelo, A., Bonaventura, A., Romano, D., & Maffioli, P. (2012) · Journal of clinical lipidology · doi:10.1016/j.jacl.2012.02.010 · Cited by 68 · see citing works

Omega-3 polyunsaturated fatty acids reduce insulin resistance and triglycerides in obese children and adolescents

Juárez-López, C., Klünder‐Klünder, M., Madrigal-Azcárate, A., & Flores‐Huerta, S. (2013) · Pediatric Diabetes · doi:10.1111/pedi.12024 · Cited by 67 · see citing works

Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice

Johnson, M. L., Lalia, A. Z., Dasari, S., Pallauf, M., Fitch, M., Hellerstein, M. K., & Lanza, I. R. (2015) · Aging Cell · doi:10.1111/acel.12352 · Cited by 66 · see citing works

ω‐3 Polyunsaturated Fatty Acid Supplementation Does Not Influence Body Composition, Insulin Resistance, and Lipemia in Women With Type 2 Diabetes and Obesity

Crochemore, I. C. C., Souza, A. F. P., de Souza, A. C. F., & Rosado, E. L. (2012) · Nutrition in Clinical Practice · doi:10.1177/0884533612444535 · Cited by 66 · see citing works

Fatty Acid Consumption and Metabolic Syndrome Components: The GOCADAN Study

Ebbesson, S. O. E., Tejero, M. E., Nobmann, E. D., López-Alvarenga, J. C., Ebbesson, L. O. E., Romenesko, T., Carter, E. A., Resnick, H. E., Devereux, R. B., MacCluer, J. W., et al. (2007) · Journal of the CardioMetabolic Syndrome · doi:10.1111/j.1559-4564.2007.07393.x · Cited by 64 · see citing works

Effects of Fish Oil Supplementation on Markers of the Metabolic Syndrome

Pedersen, M. H., Mølgaard, C., Hellgren, L. I., & Lauritzen, L. (2010) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2010.04.001 · Cited by 58 · see citing works

Supplementation of n3 Long-chain Polyunsaturated Fatty Acid Synergistically Decreases Insulin Resistance with Weight Loss of Obese Prepubertal and Pubertal Children

López‐Alarcón, M., Martínez-Coronado, A., Velarde-Castro, O., Rendón-Macías, E., & Fernández, J. R. (2011) · Archives of Medical Research · doi:10.1016/j.arcmed.2011.06.010 · Cited by 56 · see citing works

Effects of marine n-3 fatty acid supplementation on lipoprotein subclasses measured by nuclear magnetic resonance in subjects with type II diabetes

Mostad, I. L., Bjerve, K. S., Lydersen, S., & Grill, V. (2007) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602703 · Cited by 55 · see citing works

Effects of Olanzapine and Risperidone on Glucose Metabolism and Insulin Sensitivity in Chronic Schizophrenic Patients With Long-Term Antipsychotic Treatment

Smith, R. C., Lindenmayer, J., Davis, J. M., Kelly, E., Viviano, T. F., Cornwell, J., Hu, Q., Khan, A., & Vaidhyanathaswamy, S. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04446yel · Cited by 55 · see citing works

Omega-3 fatty acid therapy dose-dependently and significantly decreased triglycerides and improved flow-mediated dilation, however, did not significantly improve insulin sensitivity in patients with hypertriglyceridemia

Oh, P. C., Koh, K. K., Sakuma, I., Lim, S., Lee, Y., Lee, S., Lee, K., Han, S. H., & Shin, E. K. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.07.075 · Cited by 54 · see citing works

Fish Oil Supplementation Ameliorates Fructose-Induced Hypertriglyceridemia and Insulin Resistance in Adult Male Rhesus Macaques

Bremer, A. A., Stanhope, K. L., Graham, J. L., Cummings, B. P., Ampah, S. B., Saville, B. R., & Havel, P. J. (2013) · Journal of Nutrition · doi:10.3945/jn.113.178061 · Cited by 53 · see citing works

Effect of n -3 PUFA supplementation at different EPA:DHA ratios on the spontaneously hypertensive obese rat model of the metabolic syndrome

Molinar‐Toribio, E., Pérez‐Jiménez, J., Ramos‐Romero, S., Romeu, M., Giralt, M., Taltavull, N., Muñoz-Cortés, M., Jáuregui, O., Méndez, L., Medina, I., et al. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114514004437 · Cited by 51 · see citing works

Effect of fish oil supplementation and exercise on serum lipids and aerobic fitness.

BRILLA, L. R., & Landerholm, T. E. (1990) · PubMed · Cited by 50 · see citing works

Dietary Docosahexaenoic Acid and Eicosapentaenoic Acid Influence Liver Triacylglycerol and Insulin Resistance in Rats Fed a High-Fructose Diet

de Castro, G. S., Deminice, R., Simões-Ambrósio, L. M. C., Calder, P. C., Jordão, A. A., & Vannucchi, H. (2015) · Marine Drugs · doi:10.3390/md13041864 · Cited by 49 · see citing works

Differential Effects of High-Fish Oil and High-Lard Diets on Cells and Cytokines Involved in the Inflammatory Process in Rat Insulin-Sensitive Tissues

Lionetti, L., Mollica, M. P., Sica, R., Donizzetti, I., Gifuni, G., Pignalosa, A., Cavaliere, G., & Putti, R. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15023040 · Cited by 49 · see citing works

A randomized trial of fish oil omega-3 fatty acids on arterial health, inflammation, and metabolic syndrome in a young healthy population

Root, M. M., Collier, S. R., Zwetsloot, K. A., West, K. L., & McGinn, M. C. (2013) · Nutrition Journal · doi:10.1186/1475-2891-12-40 · Cited by 49 · see citing works

n−3 polyunsaturated fatty acids modulate metabolism of insulin-sensitive tissues: implication for the prevention of type 2 diabetes

Pinel, A., Morio, B., & Capel, F. (2013) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-013-0303-2 · Cited by 48 · see citing works

Interaction of fish oil and a glucocorticoid on metabolic responses to an oral glucose load in healthy human subjects

Delarue, J., Li, C.-H., Cohen, R., Corporeau, C., & Simon, B. (2006) · British Journal Of Nutrition · doi:10.1079/bjn20051631 · Cited by 48 · see citing works

Body and Liver Fat Mass Rather Than Muscle Mitochondrial Function Determine Glucose Metabolism in Women With a History of Gestational Diabetes Mellitus

Prikoszovich, T., Winzer, C., Schmid, A. I., Szendroedi, J., Chmelík, M., Pacini, G., Krššák, M., Moser, E., Funahashi, T., Waldhäusl, W. K., et al. (2010) · Diabetes Care · doi:10.2337/dc10-1002 · Cited by 47 · see citing works

Long-chain n-3 polyunsaturated fatty acids dissociate phosphorylation of Akt from phosphatidylinositol 3’-kinase activity in rats

Le Foll, C., Corporeau, C., Le Guen, V., Gouygou, J.-P., Bergé, J.-P., & Delarue, J. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00446.2006 · Cited by 45 · see citing works

Fish oil supplementation does not lower C‐reactive protein or interleukin‐6 levels in healthy adults

Muldoon, M. F., Laderian, B., Kuan, D. C.-H., Sereika, S. M., Marsland, A. L., & Manuck, S. B. (2015) · Journal of Internal Medicine · doi:10.1111/joim.12442 · Cited by 45 · see citing works

n-3 PUFA status in school children is associated with beneficial lipid profile, reduced physical activity and increased blood pressure in boys

Damsgaard, C. T., Stark, K. D., Hjorth, M. F., Biltoft-Jensen, A. P., Astrup, A. V., Michaelsen, K. F., & Lauritzen, L. (2013) · British Journal Of Nutrition · doi:10.1017/s0007114513000585 · Cited by 43 · see citing works

Association of dietary omega-3 fatty acids with prevalence of metabolic syndrome: The National Heart, Lung, and Blood Institute Family Heart Study

Lai, Y., Petrone, A. B., Pankow, J. S., Arnett, D. K., North, K. E., Ellison, R. C., Hunt, S. C., & Djoussé, L. (2013) · Clinical Nutrition · doi:10.1016/j.clnu.2013.05.002 · Cited by 43 · see citing works

Relationship between n-3 and n-6 plasma fatty acid levels and insulin resistance in coronary patients with and without metabolic syndrome

Nigam, A., Frasure‐Smith, N., Lespérance, F., & Julien, P. (2008) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2008.07.008 · Cited by 42 · see citing works

The association between n-3 fatty acids in erythrocyte membranes and insulin resistance: The inuit health in transition study

Thorseng, T., Witte, D. R., Vistisen, D., Borch‐Johnsen, K., Bjerregaard, P., & Jørgensen, M. E. (2009) · International Journal of Circumpolar Health · doi:10.3402/ijch.v68i4.17373 · Cited by 42 · see citing works

Effects of supplementation with omega-3 on insulin sensitivity and non-esterified free fatty acid (NEFA) in type 2 diabetic patients

Farsi, P. F., Djazayery, A., Eshraghian, M. R., Koohdani, F., Saboor-Yaraghi, A. A., Derakhshanian, H., Zarei, M., Javanbakht, M. H., & Djalali, M. (2014) · Arquivos Brasileiros de Endocrinologia &amp; Metabologia · doi:10.1590/0004-2730000002861 · Cited by 40 · see citing works

Nonalcoholic fatty liver disease: Roles of the gut and the liver and metabolic modulation by some dietary factors and especially long‐chain n‐3 PUFA

Delarue, J., & Lallès, J. P. (2015) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500346 · Cited by 37 · see citing works

The Effects of Low Dose n-3 Fatty Acids on Serum Lipid Profiles and Insulin Resistance of the Elderly: a Randomized Controlled Clinical Trial

Fakhrzadeh, H., Ghaderpanahi, M., Sharifi, F., Mirarefin, M., Badamchizade, Z., Kamrani, A. A., & Larijani, B. A. (2010) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831/a000011 · Cited by 37 · see citing works

A decreased<i>n</i>-6/<i>n</i>-3 ratio in the fat-1 mouse is associated with improved glucose tolerance

Smith, B. K., Holloway, G. P., Reza-Lopez, S., Jeram, S. M., Kang, J. X., & Ma, D. W. L. (2010) · Applied Physiology Nutrition and Metabolism · doi:10.1139/h10-066 · Cited by 35 · see citing works

Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation

Stephens, F. B., Mendis, B., Shannon, C. E., Cooper, S., Ortori, C. A., Barrett, D. A., Mansell, P., & Tsintzas, K. (2014) · Clinical Science · doi:10.1042/cs20140031 · Cited by 35 · see citing works

Docosahexaenoic Acid Supplementation Improved Lipocentric but Not Glucocentric Markers of Insulin Sensitivity in Hypertriglyceridemic Men

Kelley, D. S., Adkins, Y. C., Woodhouse, L. R., Swislocki, A., Mackey, B. E., & Siegel, D. (2011) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2011.0081 · Cited by 33 · see citing works

Docosahexaenoic Acid Content in Plasma Phospholipids and Desaturase Indices in Obese Children

Saito, E., Okada, T., Abe, Y., Kuromori, Y., Miyashita, M., Iwata, F., Hara, M., Ayusawa, M., Mugishima, H., & Kitamura, Y. (2011) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.6270 · Cited by 33 · see citing works

Decreased activity of desaturase 5 in association with obesity and insulin resistance aggravates declining long-chainn-3 fatty acid status in Cree undergoing dietary transition

Zhou, Y., Kubow, S. J., Dewailly, É., Julien, P., & Egeland, G. M. (2009) · British Journal Of Nutrition · doi:10.1017/s0007114509301609 · Cited by 32 · see citing works

Docosahexaenoic acid attenuates adipose tissue angiogenesis and insulin resistance in high fat diet‐fed middle‐aged mice via a sirt1‐dependent mechanism

Luo, X., Jia, R., Yao, Q., Xu, Y., Luo, Z., Luo, X., & Wang, N. (2016) · Molecular Nutrition &amp; Food Research · doi:10.1002/mnfr.201500714 · Cited by 30 · see citing works

Fish intake, erythrocyten-3 fatty acid status and metabolic health in Danish adolescent girls and boys

Lauritzen, L., Harsløf, L. B. S., Hellgren, L. I., Pedersen, M. H., Mølgaard, C., & Michaelsen, K. F. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511002418 · Cited by 29 · see citing works

Addition of n-3 fatty acids to a 4-hour lipid infusion does not affect insulin sensitivity, insulin secretion, or markers of oxidative stress in subjects with type 2 diabetes mellitus

Mostad, I. L., Bjerve, K. S., Basu, S., Sutton, P., Frayn, K. N., & Grill, V. (2009) · Metabolism · doi:10.1016/j.metabol.2009.06.003 · Cited by 28 · see citing works

Effects of conjugated linoleic acid plus n-3 polyunsaturated fatty acids on insulin secretion and estimated insulin sensitivity in men

Åhrén, B., Mari, A., Fyfe, C., Tsofliou, F., Sneddon, A. A., Wahle, K. W. J., Winzell, M. S., Pacini, G., & Williams, L. M. (2008) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2008.45 · Cited by 26 · see citing works

n-3 Polyunsaturated fatty acids and trans fatty acids in patients with the metabolic syndrome: a case–control study in Korea

Lee, E., Lee, S. Y., & Park, Y. (2008) · British Journal Of Nutrition · doi:10.1017/s0007114508925435 · Cited by 26 · see citing works

Functional modulation of mitochondria by eicosapentaenoic acid provides protection against ceramide toxicity to C6 glioma cells

Jeng, J.-Y., Lee, W.-H., Tsai, Y.-H., Chen, C.-Y., Chao, S.-Y., & Hsieh, R.-H. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf902021h · Cited by 24 · see citing works

Serum phospholipid omega-3 polyunsaturated fatty acids and insulin resistance in type 2 diabetes mellitus and non-alcoholic fatty liver disease

Lou, D.-J., Zhu, Q.-Q., Si, X.-W., Guan, L.-L., You, Q.-Y., Yu, Z., Zhang, A., & Li, D. (2014) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2014.04.008 · Cited by 24 · see citing works

Ratio of Dietary n-6/n-3 Polyunsaturated Fatty Acids Independently Related to Muscle Mass Decline in Hemodialysis Patients

Wong, T.-C., Chen, Y.-T., Wu, P.-Y., Chen, T., Chen, H.-H., Chen, T.-H., & Yang, S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0140402 · Cited by 24 · see citing works

Protective effect of eicosapentaenoic acid on insulin resistance in hyperlipidemic patients and on the postoperative course of cardiac surgery patients: the possible involvement of adiponectin.

(2014) · PubMed · doi:10.18926/amo/53024 · Cited by 19 · see citing works

Prevention of liver steatosis through fish oil supplementation: correlation of oxidative stress with insulin resistance and liver fatty acid content

Espinosa, A., Rodrigo Valenzuela, B., Gonzalez‐Mañán, D., D’Espessailles, A., Gormaz, J. G., Barrera, C. R., & Gladys Tapia, O. (2005) · Archivos Latinoamericanos de Nutrición · doi:10.37527/2013.63.1.004 · Cited by 11 · see citing works

Hypocaloric diet associated with the consumption of jam enriched with microencapsulated fish oil decreases insulin resistance.

Carvalho, A. P. S. D. O., Uehara, S. K., Netto, J. F. N., & Rosa, G. (2014) · PubMed · doi:10.3305/nh.2014.29.5.6654 · Cited by 9 · see citing works

Levels of eicosapentaenoic acid in obese schoolchildren with and without insulin resistance.

Sánchez‐Meza, K., Pérez, C. E. T., Sánchez-Ramírez, C. A., Muñiz‐Valencia, R., & Toro-Equihua, M. D. (2014) · PubMed · doi:10.3305/nh.2015.31.3.8047 · Cited by 5 · see citing works

Effect of Early Intervention with Omega-3 on Insulin Resistance in Patients Initiated on Olanzapine with either Sodium Valproate or Lithium: A randomized, Double-blind, Placebo-Controlled Trial.

Faghihi, T., Ghaeli, P., Adel, J., Mahmoudi‐Gharaei, J., Sharifi‎, V., & Akhondzadeh, S. (2010) · Europe PMC (PubMed Central) · Cited by 4 · see citing works

Omega-3 polyunsaturated fatty acids and their health benefits

Shahidi, F., & Ambigaipalan, P. (2018) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-111317-095850 · Cited by 1,390 · see citing works

Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments

Ruze, R., Liu, T., Zou, X., Song, J., Chen, Y., Xu, R., Yin, X., & Xu, Q. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1161521 · Cited by 799 · see citing works

Metabolites as regulators of insulin sensitivity and metabolism

Yang, Q., Vijayakumar, A., & Kahn, B. B. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0044-8 · Cited by 681 · see citing works

Significance of long chain polyunsaturated fatty acids in human health

Zárate, R., el Jaber-Vazdekis, N., Tejera, N., Pérez, J. A., & Rodríguez, C. (2017) · Clinical and Translational Medicine · doi:10.1186/s40169-017-0153-6 · Cited by 547 · see citing works

An Integrated View of Immunometabolism

Lee, Y. S., Wollam, J., & Olefsky, J. M. (2018) · Cell · doi:10.1016/j.cell.2017.12.025 · Cited by 440 · see citing works

Mitochondrial (Dys)function and Insulin Resistance: From Pathophysiological Molecular Mechanisms to the Impact of Diet

Sergi, D., Naumovski, N., Heilbronn, L. K., Abeywardena, M., O’Callaghan, N., Lionetti, L., & Luscombe-Marsh, N. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00532 · Cited by 347 · see citing works

The Role of Adipose Tissue Mitochondria: Regulation of Mitochondrial Function for the Treatment of Metabolic Diseases

Lee, J. H., Park, A., Oh, K., Lee, S. C., Kim, W. K., & Bae, K. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20194924 · Cited by 270 · see citing works

Fatty acid diets: regulation of gut microbiota composition and obesity and its related metabolic dysbiosis

Machate, D. J., Figueiredo, P. S., Marcelino, G., Guimarães, R. D. C. A., Hiane, P. A., Bogo, D., Pinheiro, V. A. Z., Oliveira, L. C. S. D., & Pott, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21114093 · Cited by 243 · see citing works

Omega-3 Fatty Acids and Insulin Resistance: Focus on the Regulation of Mitochondria and Endoplasmic Reticulum Stress

Lepretti, M., Martucciello, S., Burgos Aceves, M., Putti, R., & Lionetti, L. (2018) · Nutrients · doi:10.3390/nu10030350 · Cited by 232 · see citing works

Efficacy of Fish Oil and/or Probiotic Intervention on the Incidence of Gestational Diabetes Mellitus in an At-Risk Group of Overweight and Obese Women: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial

Pellonperä, O., Mokkala, K., Houttu, N., Vahlberg, T., Koivuniemi, E., Tertti, K., Rönnemaa, T., & Laitinen, K. (2019) · Diabetes Care · doi:10.2337/dc18-2591 · Cited by 145 · see citing works

Omega-3 long-chain polyunsaturated fatty acids: Metabolism and health implications

Khan, I. R., Hussain, M., Jiang, B., Zheng, L., Pan, Y., Hu, J., Khan, A., Ashraf, A., & Zou, X. (2023) · Progress in Lipid Research · doi:10.1016/j.plipres.2023.101255 · Cited by 119 · see citing works

Metagenomics analysis of gut microbiota in response to diet intervention and gestational diabetes in overweight and obese women: a randomised, double-blind, placebo-controlled clinical trial

Mokkala, K., Paulin, N., Houttu, N., Koivuniemi, E., Pellonperä, O., Khan, S., Pietilä, S., Tertti, K., Elo, L. L., & Laitinen, K. (2020) · Gut · doi:10.1136/gutjnl-2020-321643 · Cited by 105 · see citing works

The Impact of Diet on Immunity and Respiratory Diseases

Wypych, T. P., Marsland, B. J., & Ubags, N. D. J. (2017) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201703-255aw · Cited by 90 · see citing works

Lipid-Induced Mechanisms of Metabolic Syndrome

Denisenko, Y., Kytikovа, O. Y., Novgorodtseva, T. P., Antonyuk, M. V., Gvozdenko, T. A., & Анатольевна, К. Т. (2020) · Journal of Obesity · doi:10.1155/2020/5762395 · Cited by 78 · see citing works

Omega-3 Fatty Acids and Adipose Tissue: Inflammation and Browning

Kalupahana, N. S., Goonapienuwala, B. L., & Moustaid-Moussa, N. (2020) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-122319-034142 · Cited by 72 · see citing works

DHA-enriched fish oil reduces insulin resistance in overweight and obese adults

Abbott, K. A., Burrows, T. L., Acharya, S., Thota, R. N., & Garg, M. L. (2020) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2020.102154 · Cited by 63 · see citing works

Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner

Pal, A., Al‐Shaer, A. E., Guesdon, W., Torres, M. J., Armstrong, M., Quinn, K. D., Davis, T., Reisdorph, N. A., Neufer, P. D., Spangenburg, E. E., et al. (2020) · The FASEB Journal · doi:10.1096/fj.202000830r · Cited by 61 · see citing works

Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study

Slieker, R. C., Donnelly, L. A., Fitipaldi, H., Bouland, G. A., Giordano, G. N., Åkerlund, M., Gerl, M. J., Ahlqvist, E., Ali, A., Dragan, I., et al. (2021) · Diabetes · doi:10.2337/db20-1281 · Cited by 58 · see citing works

The Mediterranean diet from past to future: Key concepts from the second “Ancel Keys” International Seminar

Russo, G. L., Siani, A., Fogliano, V., Geleijnse, J. M., Giacco, R., Giampaoli, S., Iacoviello, L., Kromhout, D., Lionetti, L., Naska, A., et al. (2021) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2020.12.020 · Cited by 58 · see citing works

A Randomized Double-Blinded, Placebo-Controlled Trial Investigating the Effect of Fish Oil Supplementation on Gene Expression Related to Insulin Action, Blood Lipids, and Inflammation in Gestational Diabetes Mellitus-Fish Oil Supplementation and Gestational Diabetes

Jamilian, M., Samimi, M., Mirhosseini, N. Z., Ebrahimi, F. A., Aghadavod, E., Taghizadeh, M., & Asemi, Z. (2018) · Nutrients · doi:10.3390/nu10020163 · Cited by 57 · see citing works

Probiotic and omega-3 polyunsaturated fatty acids supplementation reduces insulin resistance, improves glycemia and obesity parameters in individuals with type 2 diabetes: A randomised controlled trial

Kobyliak, N. M., Falalyeyeva, T. M., Mykhalchyshyn, G., Molochek, N., Savchuk, О., Kyriienko, D., & Komisarenko, I. (2020) · Obesity Medicine · doi:10.1016/j.obmed.2020.100248 · Cited by 54 · see citing works

Omega-3 polyunsaturated fatty acids prevent obesity by improving tricarboxylic acid cycle homeostasis

Liu, R., Chen, L., Wang, Z., Zheng, X., Hou, Z., Zhao, D., Long, J., & Liu, J. (2020) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2020.108503 · Cited by 47 · see citing works

The Potential Role of Fish-Derived Protein Hydrolysates on Metabolic Health, Skeletal Muscle Mass and Function in Ageing

Lees, M. J., & Carson, B. P. (2020) · Nutrients · doi:10.3390/nu12082434 · Cited by 46 · see citing works

Exercise Training Reduces Inflammation of Adipose Tissue in the Elderly: Cross-Sectional and Randomized Interventional Trial

Čížková, T., Štěpán, M., Daďová, K., Ondrůjová, B., Sontáková, L., Krauzová, E., Matouš, M., Koc, M., Gojda, J., Kračmerová, J., et al. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa630 · Cited by 46 · see citing works

In vitro micro-physiological model of the inflamed human adipose tissue for immune-metabolic analysis in type II diabetes

Kongsuphol, P., Gupta, S., Liu, Y., Gourikutty, S. B. N., Biswas, S. K., & Ramadan, Q. (2019) · Scientific Reports · doi:10.1038/s41598-019-41338-3 · Cited by 44 · see citing works

The role of omega-3 polyunsaturated fatty acid supplementation in the management of type 2 diabetes mellitus: A narrative review

Itsiopoulos, C., Marx, W., Mayr, H. L., Tatucu-Babet, O. A., Dash, S. R., George, E. S., Trakman, G. L., Kelly, J. T., Thomas, C. J., & Brazionis, L. (2018) · Journal of Nutrition &amp; Intermediary Metabolism · doi:10.1016/j.jnim.2018.02.002 · Cited by 37 · see citing works

ω-3PUFA supplementation ameliorates adipose tissue inflammation and insulin-stimulated glucose disposal in subjects with obesity: a potential role for apolipoprotein E

Hernandez, J. D., Li, T., Rau, C. M., LeSuer, W. E., Wang, P., Coletta, D. K., Madura, J. A., Jacobsen, E. A., & Filippis, E. D. (2021) · International Journal of Obesity · doi:10.1038/s41366-021-00801-w · Cited by 36 · see citing works

A comprehensive review of omega-3 fatty acids: Sources, industrial applications, and health benefits

Saidaiah, P., Banu, Z., Khan, A. A., Geetha, A., & Somraj, B. (2024) · Annals of Phytomedicine An International Journal · doi:10.54085/ap.2024.13.1.20 · Cited by 34 · see citing works

GPR120 agonists for the treatment of diabetes: a patent review (2014 present)

Zhang, X., & Macielag, M. J. (2020) · Expert Opinion on Therapeutic Patents · doi:10.1080/13543776.2020.1811852 · Cited by 33 · see citing works

Novel emulsions–based technological approaches for the protection of omega–3 polyunsaturated fatty acids against oxidation processes – A comprehensive review

Perez, J. A. V., Ochando-Pulido, J. M., la Fuente, E. B., & Martinez-Ferez, A. (2021) · Food Structure · doi:10.1016/j.foostr.2021.100175 · Cited by 33 · see citing works

Cardiometabolic Risk Factors at 5 Years After Omega-3 Fatty Acid Supplementation in Infancy

See, V. H. L., Mori, T. A., Prescott, S. L., Beilin, L. J., Burrows, S., & Huang, R. (2018) · PEDIATRICS · doi:10.1542/peds.2016-2623 · Cited by 32 · see citing works

Improvement of insulin resistance via increase of GLUT4 and PPARγ in metabolic syndrome‐induced rats treated with omega‐3 fatty acid or l ‐carnitine

Zayed, E. A., Ain-Shoka, A. A., El-Shazly, K. A., & Latif, H. A. A. E. (2018) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.22218 · Cited by 32 · see citing works

Effect of chronic consumption of pistachios (Pistacia vera L.) on glucose metabolism in pre-diabetics and type 2 diabetics: A systematic review

Ribeiro, P. V. D. M., da Silva, A., de Almeida, A. P., Hermsdorff, H. H. M., & Alfenas, R. D. C. G. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1392290 · Cited by 28 · see citing works

Distinct Influence of Omega-3 Fatty Acids on the Plasma Metabolome of Healthy Older Adults

Xyda, S., Vučković, I., Petterson, X.-M. T., Dasari, S., Lalia, A. Z., Parvizi, M., Macura, S. I., & Lanza, I. R. (2019) · The Journals of Gerontology Series A · doi:10.1093/gerona/glz141 · Cited by 28 · see citing works

EPA and DHA elicit distinct transcriptional responses to high-fat feeding in skeletal muscle and liver

Kunz, H., Dasari, S., & Lanza, I. R. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00083.2019 · Cited by 27 · see citing works

Shellfish consumption and health: A comprehensive review of human studies and recommendations for enhanced public policy

Xu, L., Cai, J., Gao, T., & Ma, A. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1878098 · Cited by 27 · see citing works

Role of Omega-3 Fatty Acids on Lipid Profile in Diabetic Dyslipidaemia: Single Blind, Randomised Clinical Trial

Chauhan, S. (2017) · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · doi:10.7860/jcdr/2017/20628.9449 · Cited by 27 · see citing works

Potentially Beneficial Effects on Healthy Aging by Supplementation of the EPA-Rich Microalgae Phaeodactylum tricornutum or Its Supernatant—A Randomized Controlled Pilot Trial in Elderly Individuals

Stiefvatter, L., Frick, K., Lehnert, K., Vetter, W., Montoya‐Arroyo, A., Frank, J., Schmid‐Staiger, U., & Bischoff, S. C. (2022) · Marine Drugs · doi:10.3390/md20110716 · Cited by 26 · see citing works

Beneficial effects of eicosapentaenoic acid on the metabolic profile of obese female mice entails upregulation of HEPEs and increased abundance of enteric Akkermansia muciniphila

Pal, A., Sun, S., Armstrong, M., Manke, J., Reisdorph, N., Adams, V. R., Kennedy, A. J., Zu, Y., Moustaïd‐Moussa, N., Carroll, I. M., et al. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2021.159059 · Cited by 24 · see citing works

A randomized control trial of the impact of LCPUFA‐ω3 supplementation on body weight and insulin resistance in pubertal children with obesity

López‐Alarcón, M., Icaza, P. I., Márquez‐Maldonado, M. C., Armenta‐Alvarez, A., Barbosa-Cortés, L., Maldonado‐Hernández, J., Piña-Aguero, M. I., Barradas-Vázquez, A. S., Núñez-García, B. A., Rodríguez‐Cruz, M., et al. (2018) · Pediatric Obesity · doi:10.1111/ijpo.12499 · Cited by 23 · see citing works

Increased plasma levels of palmitoleic acid may contribute to beneficial effects of Krill oil on glucose homeostasis in dietary obese mice

Rossmeisl, M., Pavlišová, J., Bardová, K., Kalendová, V., Buresova, J., Kuda, O., Kroupova, P., Staňková, B., TVRZICKÁ, E., Fišerová, E., et al. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2020.158732 · Cited by 24 · see citing works

Associations between omega-3 fatty acids and insulin resistance and body composition in women with polycystic ovary syndrome

Lu, L., Li, X., Lv, L., Xu, Y., Wu, B., & Huang, C. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1016943 · Cited by 22 · see citing works

Omega-3 fatty acid blood levels are inversely associated with cardiometabolic risk factors in HFpEF patients: the Aldo-DHF randomized controlled trial

Lechner, K., Scherr, J., Lorenz, E., Lechner, B., Haller, B., Krannich, A., Halle, M., Wachter, R., Duvinage, A., & Edelmann, F. (2021) · Clinical Research in Cardiology · doi:10.1007/s00392-021-01925-9 · Cited by 21 · see citing works

High-Fish Oil and High-Lard Diets Differently Affect Testicular Antioxidant Defense and Mitochondrial Fusion/Fission Balance in Male Wistar Rats: Potential Protective Effect of ω3 Polyunsaturated Fatty Acids Targeting Mitochondria Dynamics

Migliaccio, V., Sica, R., Gregorio, I. D., Putti, R., & Lionetti, L. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20123110 · Cited by 21 · see citing works

The role of selected nutraceuticals in management of prediabetes and diabetes: An updated review of the literature

Derosa, G., D’Angelo, A., & Maffioli, P. (2022) · Phytotherapy Research · doi:10.1002/ptr.7564 · Cited by 24 · see citing works

Reduced phasic dopamine release and slowed dopamine uptake occur in the nucleus accumbens after a diet high in saturated but not unsaturated fat

Barnes, C. N., Wallace, C. W., Jacobowitz, B. S., & Fordahl, S. C. (2020) · Nutritional Neuroscience · doi:10.1080/1028415x.2019.1707421 · Cited by 20 · see citing works

Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake

Hu, S., He, X., Nie, J., Hou, J., Wu, J., Liu, X., Wei, Y., Tang, H., Sun, W.-X., Zhou, S.-X., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110509 · Cited by 19 · see citing works

A systematic review and meta-analysis of randomized controlled trials to evaluate plant-based omega-3 polyunsaturated fatty acids in nonalcoholic fatty liver disease patient biomarkers and parameters

Moore, E., Patanwala, I., Jafari, A., Davies, I. G., Kirwan, R., Newson, L., Mazidi, M., & Lane, K. E. (2023) · Nutrition Reviews · doi:10.1093/nutrit/nuad054 · Cited by 20 · see citing works

Treatment with a novel agent combining docosahexaenoate and metformin increases protectin DX and IL‐6 production in skeletal muscle and reduces insulin resistance in obese diabetic db/db mice

Mitchell, P. L., Nachbar, R. T., Lachance, D., St‐Pierre, P., Trottier, J., Barbier, O., & Marette, A. (2016) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12818 · Cited by 19 · see citing works

Docosahexaenoic and eicosapentaenoic fatty acids differentially regulate glucose and fatty acid metabolism in L6 rat skeletal muscle cells

Katsnelson, G., & Ceddia, R. B. (2020) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00304.2020 · Cited by 19 · see citing works

Vascepa protects against high-fat diet-induced glucose intolerance, insulin resistance, and impaired β-cell function

Rijjal, D. A., Liu, Y., Lai, M., Song, Y., Danaei, Z., Wu, A., Mohan, H., Li, W., Schopfer, F. J., Dai, F. F., et al. (2021) · iScience · doi:10.1016/j.isci.2021.102909 · Cited by 19 · see citing works

Mechanism of the components compatibility of Scutellariae Radix and Coptidis Rhizoma on mice with hyperlipidemia by regulating the Cyp4a family

Gao, Y., Sun, Y.-Y., Bai, D., & Wu, X.-X. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118263 · Cited by 18 · see citing works

Immunometabolism in type 2 diabetes mellitus: tissue-specific interactions

Pinheiro-Machado, E., Gurgul-Convey, E., & Marzec, M. (2020) · Archives of medical science : AMS · doi:10.5114/aoms.2020.92674 · Cited by 21 · see citing works

Fish Oil And/Or Probiotics Intervention in Overweight/Obese Pregnant Women and Overweight Risk in 24‐Month‐Old Children

Saros, L., Vahlberg, T. J., Koivuniemi, E., Houttu, N., Niinikoski, H., Tertti, K., & Laitinen, K. (2022) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000003659 · Cited by 17 · see citing works

Fatty acid transport receptor soluble CD36 and dietary fatty acid pattern in type 2 diabetic patients: a comparative study

Ekici, M., Kısa, Ü., Durmaz, Ş. A., Uğur, E., & Nergiz‐Unal, R. (2018) · British Journal Of Nutrition · doi:10.1017/s0007114517003269 · Cited by 17 · see citing works

Impact of combined consumption of fish oil and probiotics on the serum metabolome in pregnant women with overweight or obesity

Mokkala, K., Vahlberg, T. J., Houttu, N., Koivuniemi, E., Lahti, L., & Laitinen, K. (2021) · EBioMedicine · doi:10.1016/j.ebiom.2021.103655 · Cited by 17 · see citing works

Protective effects of extra virgin olive oil and exercise training on rat skeletal muscle against high-fat diet feeding

Yeo, D., Zhang, T., Liu, T., Zhang, Y., Kang, C., & Ji, L. L. (2021) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2021.108902 · Cited by 16 · see citing works

Omega-3 Fatty Acid Supplementation Improves Heart Rate Variability in Obese Children

Baumann, C., Rakowski, U., & Buchhorn, R. (2018) · International Journal of Pediatrics · doi:10.1155/2018/8789604 · Cited by 16 · see citing works

A Randomized Trial of ω-3 Fatty Acid Supplementation and Circulating Lipoprotein Subclasses in Healthy Older Adults

Moosavi, D., Vučković, I., Kunz, H., & Lanza, I. R. (2022) · Journal of Nutrition · doi:10.1093/jn/nxac084 · Cited by 15 · see citing works

The emerging global phenomenon of sarcopenic obesity: Role of functional foods; a conference report

Shao, A. E., Campbell, W. W., Chen, C. O., Mittendorfer, B., Rivas, D. A., & Griffiths, J. C. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.03.048 · Cited by 15 · see citing works

The effects of omega-3 fatty acids supplementation on metabolic status in pregnant women: a systematic review and meta-analysis of randomized controlled trials

Amirani, E., Asemi, Z., Asbaghi, O., Milajerdi, A., Reiner, Ž., Mansournia, M. A., Hallajzadeh, J., Moazzami, B., & Chaichian, S. (2020) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-020-00558-5 · Cited by 15 · see citing works

The Impacts of Fish Oil and/or Probiotic Intervention on Low-Grade Inflammation, IGFBP-1 and MMP-8 in Pregnancy: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial

Houttu, N., Mokkala, K., Koivuniemi, E., Pellonperä, O., Juhila, J., Sorsa, T. A., & Laitinen, K. (2020) · Biomolecules · doi:10.3390/biom11010005 · Cited by 15 · see citing works

Prevention of Potential Adverse Metabolic Effects of a Supplementation with Omega-3 Fatty Acids Using a Genetic Score Approach

Franck, M., de Toro‐Martín, J., Guénard, F., Rudkowska, I., Lemieux, S., Lamarche, B., Couture, P., & Vohl, M. (2019) · Lifestyle Genomics · doi:10.1159/000504022 · Cited by 14 · see citing works

Potential Mechanisms by Which Hydroxyeicosapentaenoic Acids Regulate Glucose Homeostasis in Obesity

Shaikh, S. R., Virk, R., & Dyke, T. E. V. (2022) · Advances in Nutrition · doi:10.1093/advances/nmac073 · Cited by 14 · see citing works

Plasma fatty acids in de novo lipogenesis pathway are associated with diabetogenic indicators among adults: NHANES 2003–2004

Yu, E. A., Hu, P. J., & Mehta, S. (2018) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy165 · Cited by 14 · see citing works

Nutraceuticals and Supplements in Management of Prediabetes and Diabetes

Derosa, G., D’Angelo, A., Angelini, F., Belli, L., Cicero, A. F. G., ROS, R. D., Pergola, G. D., Gaudio, G. V., Lupi, A., Sartore, G., et al. (2024) · Nutrients · doi:10.3390/nu17010014 · Cited by 17 · see citing works

Polyunsaturated Fatty Acids on Cardiovascular Health: Revealing Potentials of Functional Food

Drenjančević, I., Kralik, G., Kralik, Z., Mihalj, M., Stupin, A., Novak, S., & Grčević, M. (2017) · InTech eBooks · doi:10.5772/67033 · Cited by 13 · see citing works

Docosahexaenoic Acid Supplementation is Not Anti- Inflammatory in Adipose Tissue of Healthy Obese Postmenopausal Women

Holt, P. R., Alemán, J. O., Walker, J. M., Jiang, C. S., Liang, Y., de Rosa, J. C., Giri, D. D., Iyengar, N. M., Milne, G. L., Hudis, C. A., et al. (2017) · International Journal Of Nutrition · doi:10.14302/issn.2379-7835.ijn-17-1636 · Cited by 11 · see citing works

Association between plasma phospholipid omega-3 polyunsaturated fatty acids and type 2 diabetes is sex dependent: The Hunter Community Study

Abbott, K. A., Burrows, T. L., Thota, R. N., Alex, A., Acharya, S., Attia, J., McEvoy, M., & Garg, M. L. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2019.04.007 · Cited by 10 · see citing works

The effect of traditional diet on glucose homoeostasis in carriers and non-carriers of a common TBC1D4 variant in Greenlandic Inuit: a randomised crossover study

Lewis, J. I., Lind, M. V., Møller, G., Hansen, T. F., Pedersen, H., Christensen, M. M. B., Laursen, J. C., Nielsen, S., Ottendahl, C. B., Larsen, C. V. L., et al. (2023) · British Journal Of Nutrition · doi:10.1017/s000711452300106x · Cited by 10 · see citing works

Omega-3 polyunsaturated fatty acids promote SNAREs mediated GLUT4 vesicle docking and fusion

Zhang, Y., He, L., Chen, X., Shentu, P., Xu, Y., & Jiao, J. (2021) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2021.108912 · Cited by 10 · see citing works

No Effect of Dietary Fish Oil Supplementation on the Recruitment of Brown and Brite Adipocytes in Mice or Humans under Thermoneutral Conditions

Maurer, S., Dieckmann, S., Lund, J. T., Fromme, T., Hess, A. L., Colson, C., Kjølbæk, L., Astrup, A. V., Gillum, M. P., Larsen, L. H., et al. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202000681 · Cited by 10 · see citing works

Role of natural compounds in non-alcoholic fatty liver diseases (NAFLD): a mechanistic approach

Wal, P., Yadav, S., Jha, S. K., Singh, A., Bhargavi, B., Shivaram, R., Imran, M., & Aziz, N. (2025) · Egyptian Liver Journal · doi:10.1186/s43066-025-00452-w · Cited by 9 · see citing works

Docosahexaenoic Acid-Rich Fish Oil Supplementation Reduces Kinase Associated with Insulin Resistance in Overweight and Obese Midlife Adults

Thota, R. N., Rosato, J. I., Burrows, T. L., Dias, C. B., Abbott, K. A., Martins, R. N., & Garg, M. L. (2020) · Nutrients · doi:10.3390/nu12061612 · Cited by 9 · see citing works

Target Therapies for NASH/NAFLD: From the Molecular Aspect to the Pharmacological and Surgical Alternatives

Finotti, M., Romano, M., Auricchio, P., Scopelliti, M., Brizzolari, M., Grossi, U., Piccino, M., Benvenuti, S., Morana, G., Cillo, U., et al. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11060499 · Cited by 9 · see citing works

Diet, Exercise, and the Metabolic Syndrome: Enrollment of the Mitochondrial Machinery

Silvestri, E., & Giacco, A. (2022) · Nutrients · doi:10.3390/nu14214519 · Cited by 10 · see citing works

Marine ω-3 PUFA Supplementation Enhances FFAR4 Activation and Reduces Inflammatory Markers in PBMC of Subjects with Obesity: A Randomized Controlled Trial (EPICO)

Reyes-Pérez, S. D., Cambrón-Mora, D., Torres-Vanegas, J., Mojica-Zamudio, K. L., Olaez-Ramos, C. E., Lauriano-Rivera, R. G., Rivera-Valdes, J. J., Torres‐Castillo, N., Valencia-Sosa, E., Rodriguez‐Echevarría, R., et al. (2025) · Nutrients · doi:10.3390/nu17233630 · Cited by 8 · see citing works

Resolvin E1 Derived from Eicosapentaenoic Acid Prevents Hyperinsulinemia and Hyperglycemia in a Host Genetic Manner

Pal, A., Al‐Shaer, A. E., Guesdon, W., Torres, M. J., Armstrong, M., Quinn, K. D., Davis, T., Reisdorph, N. A., Neufer, P. D., Spangenburg, E. E., et al. (2020) · Digital Commons - University of South Florida (University of South Florida) · Cited by 8 · see citing works

The Effect of a Fish Oil and/or Probiotic Intervention from Early Pregnancy Onwards on Colostrum Immune Mediators: A Randomized, Placebo‐Controlled, Double‐Blinded Clinical Trial in Overweight/Obese Mothers

Soukka, J. J. H., Polari, L., Kalliomäki, M. A., Saros, L., Laajala, T. D., Vahlberg, T. J., Toivola, D. M., & Laitinen, K. (2023) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202200446 · Cited by 7 · see citing works

Omega Yağ Asitleri: Biyolojik Etkileri ve Bitkisel Kaynakları

SALAR, B., & Kuruüzüm‐Uz, A. (2021) · Hacettepe University Journal of the Faculty of Pharmacy · doi:10.52794/hujpharm.920079 · Cited by 7 · see citing works

The combination of omega−3 fatty acids with high doses of vitamin D3 elevate A1c levels: A randomized Clinical Trial in people with vitamin D deficiency

Barham, A., Mohammad, B. A., Hasoun, L., Awwad, S. H., Mosleh, I. M., Aljaberi, A., & Abu‐Samak, M. (2021) · International Journal of Clinical Practice · doi:10.1111/ijcp.14779 · Cited by 8 · see citing works

Effects of eicosapentaenoic acid on serum levels of selenoprotein P and organ‐specific insulin sensitivity in humans with dyslipidemia and type 2 diabetes

Takeshita, Y., Teramura, C., Kamoshita, K., Takayama, H., Nakagawa, H., Enyama, Y., Ishii, K., Tanaka, T., Goto, H., Nakano, Y., et al. (2021) · Journal of Diabetes Investigation · doi:10.1111/jdi.13699 · Cited by 6 · see citing works

The effect of co supplementation of omega-3 and vitamin D on cardio metabolic risk factors and psychological distress in reproductive-aged women with prediabetes and hypovitaminosis D: a study protocol for a randomized controlled trial

Rajabi‐Naeeni, M., Dolatian, M., Qorbani, M., & Vaezi, A. A. (2019) · Trials · doi:10.1186/s13063-019-3948-5 · Cited by 7 · see citing works

Fish in the Mediterranean diet

Molina‐Vega, M., Gómez‐Pérez, A. M., & Tinahones, F. J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818649-7.00025-4 · Cited by 8 · see citing works

Two weeks of single-leg immobilization alters intramyocellular lipid storage characteristics in healthy, young women

Black, M. N., Wilkinson, J. A., Webb, E. K., Kamal, M., Bahniwal, R., McGlory, C., Phillips, S. M., & Devries, M. C. (2021) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00878.2019 · Cited by 6 · see citing works

DNA Methylation and Subgenome Dominance Reveal the Role of Lipid Metabolism in Jinhu Grouper Heterosis

Liu, Y., Wang, L., Li, Z., Li, L., Chen, D., Duan, P., Wang, X., Qiu, Y., Ding, X., Su, J., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25179740 · Cited by 6 · see citing works

Docosahexaenoic acid supplementation in gestational diabetes mellitus and neonatal metabolic health biomarkers

Xu, Y., Wang, W., Zhang, Q., Yang, M., Zhang, L., He, H., Dong, Y., Ouyang, F., Gao, Y., Zhang, J., et al. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1089131 · Cited by 6 · see citing works

Predicting Skeletal Muscle and Whole-Body Insulin Sensitivity Using NMR-Metabolomic Profiling

Klén, R., Honka, M., Hannukainen, J. C., Huovinen, V., Bucci, M., Latva‐Rasku, A., Venäläinen, M. S., Kalliokoski, K. K., Virtanen, K. A., Läutamaki, R., et al. (2020) · Journal of the Endocrine Society · doi:10.1210/jendso/bvaa026 · Cited by 6 · see citing works

Human Gut Microbiota and the Influence of Probiotics, Prebiotics, and Micronutrients

Pyle, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819265-8.00076-0 · Cited by 6 · see citing works

n-3 Polyunsaturated Fatty Acids in Type 2 Diabetes Mellitus

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Israelian, N., & Danska, J. S. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-70178-3_7 · Cited by 5 · see citing works

Polyphenols reverse hyperglycemia-induced adipocyte dysfunction: A Metabolomic and Lipidomic study of efficacy

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Fedor, D. M., & Kelley, D. S. (2009) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e3283218299 · Cited by 229 · see citing works

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Effects of n-3 Fatty Acids Supplementation on Insulin Resistance

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