The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
The incidence of Type I diabetes has not increased but shifted to a younger age at diagnosis in the 0–34 years group in Sweden 1983 to 1998
Open accessAbstract
Aims/hypothesis To analyse the incidence of Type I (insulin-dependent) diabetes mellitus in the 0-34 years age group in Sweden 1983-1998.Methods Incidence and cumulative incidence per 100 000 and Poisson regression analysis of age-period effects was carried out using 11 751 cases from two nation-wide prospective registers.Results Incidence (95%-CI) was 21.4 (20.8-21.9) in men and 17.1 (16.6-17.5) in women between 0 and 34 years of age. In boys aged 0-14 and girls aged 0-12 years the incidence increased over time, but it tended to decrease at older age groups, especially in men. Average cumulative incidence at 35 years was 748 in men and 598 in women. Cumulative incidence in men was rather stable during four 4-year periods (736, 732, 762, 756), while in women it varied more (592, 542, 617, 631). In males aged 0-34 years, the incidence did not vary between the 4-year periods ( p=0.63), but time changes among the 3-year age groups differed ( p<0.001). In females the incidence between the periods varied ( p<0.001), being lower in 1987-1990 compared to 1983-1986, but time changes in the age groups did not differ ( p=0.08). For both sexes median age at diagnosis was higher in 1983-1986 than in 1995-1998 ( p<0.001) (15.0 and 12.5 years in males; 11.9 and 10.4 in females, respectively).Conclusion/interpretation During a 16-year period the incidence of Type I diabetes did not increase in the 0-34 years age group in Sweden, while median age at diagnosis decreased. A shift to younger age at diagnosis seems to explain the increasing incidence of childhood Type I diabetes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Many reports indicate an excess of T1D cases in male adults after the pubertal years (male-female ratio ≥1.5) in populations of European origin 31–34.”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [33]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Type 1 diabetes: new perspectives on disease pathogenesis and treatment
Atkinson, M. A., & Eisenbarth, G. S. (2001) · The Lancet · doi:10.1016/s0140-6736(01)05415-0 · Cited by 1,491
Diabetes Mellitus: Report of a WHO Study Group.
(1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-104-4-597_2 · Cited by 1,030
Onkamo, P., Väänänen, S., Karvonen, M., & Tuomilehto, J. (1999) · Diabetologia · doi:10.1007/s001250051309 · Cited by 984
Impaired Insulin Action in Puberty
Amiel, S. A., Sherwin, R. S., Simonson, D. C., Lauritano, A. A., & Tamborlane, W. V. (1986) · New England Journal of Medicine · doi:10.1056/nejm198607243150402 · Cited by 960
Insulin resistance during puberty: results from clamp studies in 357 children.
Moran, A., Jacobs, D. R., Steinberger, J., Hong, C. P., Prineas, R. J., Luepker, R. V., & Sinaiko, A. R. (1999) · Diabetes · doi:10.2337/diabetes.48.10.2039 · Cited by 869
Variation and trends in incidence of childhood diabetes in Europe
(2000) · The Lancet · doi:10.1016/s0140-6736(99)07125-1 · Cited by 755
[WHO Expert Committee on diabetes mellitus].
Reitsma, W. D., & Terpstra, J. (1981) · PubMed · Cited by 556
BMI in Childhood and Its Association with Height Gain, Timing of Puberty, and Final Height
He, Q., & KARLBERG, J. P. E. (2001) · Pediatric Research · doi:10.1203/00006450-200102000-00019 · Cited by 450
Karvonen, M., Tuomilehto, J., Libman, I. M., & Laporte, R. E. (1993) · Diabetologia · doi:10.1007/bf02374468 · Cited by 380
Obesity, increased linear growth, and risk of type 1 diabetes in children.
Hyppönen, E., Virtanen, S. M., Kenward, M. G., Knip, M., Åkerblom, H. K., & Childhood Diabetes in Finland Study Group (2000) · Diabetes Care · doi:10.2337/diacare.23.12.1755 · Cited by 284
Cited by
Sorted by citations
Patterson, C. C., Dahlquist, G. G., Gyürüs, E., Green, A., & Soltész, G. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60568-7 · Cited by 1,854
Self-citationEpidemiology of type 1 diabetes
Maahs, D. M., West, N. A., Lawrence, J. M., & Mayer-Davis, E. J. (2010) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2010.05.011 · Cited by 1,092
Pubertal transitions in health
Patton, G. C., & Viner, R. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60366-3 · Cited by 940
Obesity in autoimmune diseases: Not a passive bystander
Versini, M., Jeandel, P.-Y., Rosenthal, E., & Shoenfeld, Y. (2014) · Autoimmunity Reviews · doi:10.1016/j.autrev.2014.07.001 · Cited by 694
“Although a number of studies demonstrated that among heavier children T1D occurs at a younger age [242–244], several authors argue that this is balanced by a decreased incidence among older age groups, resulting in a stable overall risk [245,246].”
Meier, J. J., Butler, A. E., Saisho, Y., Monchamp, T., Galasso, R., Bhushan, A., Rizza, R. A., & Butler, P. C. (2008) · Diabetes · doi:10.2337/db07-1369 · Cited by 683
“The incidence of type 1 diabetes is also increasing in early childhood (less than three years of age)(33).”
BackgroundPalmer, A. J., Roze, S., Valentine, W. J., Minshall, M. E., FOOS, V., Lurati, F. M., Lammert, M., & Spinas, G. A. (2004) · Current Medical Research and Opinion · doi:10.1185/030079904x1980 · Cited by 528
Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study
Harjutsalo, V., Sjöberg, L., & Tuomilehto, J. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60765-5 · Cited by 666
Environmental Triggers and Determinants of Type 1 Diabetes
Knip, M., Veijola, R., Virtanen, S. M., Hyöty, H., Vaarala, O., & Åkerblom, H. K. (2005) · Diabetes · doi:10.2337/diabetes.54.suppl_2.s125 · Cited by 502
Age–period–cohort models for the Lexis diagram
Carstensen, B. (2007) · Statistics in Medicine · doi:10.1002/sim.2764 · Cited by 506
Type 1 diabetes: pathogenesis and prevention
Gillespie, K. M. (2006) · Canadian Medical Association Journal · doi:10.1503/cmaj.060244 · Cited by 415
Worldwide childhood type 1 diabetes incidence–what can we learn from epidemiology?
Soltesz, G., Patterson, C., Dahlquist, G., & EURODIAB Study Group (2007) · Pediatric Diabetes · doi:10.1111/j.1399-5448.2007.00280.x · Cited by 371
Self-citationAberrant gut microbiota composition at the onset of type 1 diabetes in young children
de Goffau, M. C., Fuentes, S., van den Bogert, B., Honkanen, H., de Vos, W. M., Welling, G. W., Hyöty, H., & Harmsen, H. J. M. (2014) · Diabetologia · doi:10.1007/s00125-014-3274-0 · Cited by 333
“Like many autoimmune diseases, the incidence of type 1 diabetes is increasing worldwide, showing a particularly sharp increase among children under the age of 5 years [20–23].”
BackgroundGAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus
Ludvigsson, J., Krisky, D., Casas, R., Battelino, T., Castaño, L., Greening, J., Kordonouri, O., Otonkoski, T., Pozzilli, P., Robert, J.-J., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1107096 · Cited by 340
Global epidemiology of type 1 diabetes in young adults and adults: a systematic review
Diaz-Valencia, P. A., Bougnères, P., & Valleron, A.-J. (2015) · BMC Public Health · doi:10.1186/s12889-015-1591-y · Cited by 294
“The corresponding countries are (1997) [32]; DK: Denmark [34]; ES1: Spain, Catalonia [54]; ES2: Spain, Islamic Republic of) [15]; IT: Italy [45,46]; SE: Sweden [63], TW: Taiwan Figure 3 (See legend on next page.)”
BackgroundInfluentialThe Emerging Global Epidemic of Type 1 Diabetes
Tuomilehto, J. (2013) · Current Diabetes Reports · doi:10.1007/s11892-013-0433-5 · Cited by 292
Zendehdel, K. (2003) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djg105 · Cited by 280
The geoepidemiology of type 1 diabetes
Borchers, A. T., Uibo, R., & Gershwin, M. E. (2009) · Autoimmunity Reviews · doi:10.1016/j.autrev.2009.12.003 · Cited by 269
Incidence of type 1 diabetes in China, 2010-13: population based study
Weng, J., Zhou, Z., Guo, L., Zhu, D., Ji, L., Luo, X., Mu, Y., & Jia, W. (2018) · BMJ · doi:10.1136/bmj.j5295 · Cited by 316
Relationship between β‐cell mass and diabetes onset
Matveyenko, A. V., & Butler, P. C. (2008) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2008.00939.x · Cited by 249
Thirty Years of Prospective Nationwide Incidence of Childhood Type 1 Diabetes
Berhan, Y., Waernbaum, I., Lind, T., Möllsten, A., Dahlquist, G., & for the Swedish Childhood Diabetes Study Group* (2011) · Diabetes · doi:10.2337/db10-0813 · Cited by 237
Self-citationIncreasing incidence of type 1 diabetes in 0- to 17-year-old Colorado youth
Vehik, K., Hamman, R. F., Lezotte, D., Norris, J. M., Klingensmith, G., Bloch, C., Rewers, M., & Dabelea, D. (2007) · Diabetes Care · doi:10.2337/dc06-1837 · Cited by 226
Can we slow the rising incidence of childhood-onset autoimmune diabetes? The overload hypothesis
Dahlquist, G. G. (2005) · Diabetologia · doi:10.1007/s00125-005-0076-4 · Cited by 197
“In Sweden, a nationwide prospective register found no increase in young adults aged 15–34 years, and analysis of cumulative rates indicated a shift towards a younger age of onset rather than an overall rise in type 1 diabetes, at least up to the age of 35 [ 4 ].”
BackgroundSelf-citationTesting the Accelerator Hypothesis
Kibirige, M. S., Metcalf, B. S., Renuka, R., & Wilkin, T. J. (2003) · Diabetes Care · doi:10.2337/diacare.26.10.2865 · Cited by 192
Incidence of Type 1 and Type 2 Diabetes in Adults Aged 30–49 Years
Bruno, G., Runzo, C., Cavallo‐Perin, P., Merletti, F., Rivetti, M., Pinach, S., Novelli, G., Trovati, M., Cerutti, F., Pagano, G., et al. (2005) · Diabetes Care · doi:10.2337/diacare.28.11.2613 · Cited by 187
Knerr, I., Wolf, J., Reinehr, T., Stachow, R., Grabert, M., Schober, E., Rascher, W., Holl, R. W., & Austria, O. B. O. T. D. S. I. O. G. A. (2005) · Diabetologia · doi:10.1007/s00125-005-0033-2 · Cited by 178
The changing epidemiology of type 1 diabetes: why is it going through the roof?
Vehik, K., & Dabelea, D. (2010) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.1141 · Cited by 181
“decreasing rates later in life [43,57–59], suggesting that”
BackgroundBetts, P. R., Mulligan, J., Ward, P., Smith, B., & Wilkin, T. J. (2004) · Diabetic Medicine · doi:10.1111/j.1464-5491.2004.01368.x · Cited by 161
Al‐Salami, H., Butt, G., Fawcett, J. P., Tucker, I. G., Goločorbin-Kon, S., & Mikov, M. (2008) · European Journal of Drug Metabolism and Pharmacokinetics · doi:10.1007/bf03191026 · Cited by 148
Environmental factors in the development of Type 1 diabetes
Peng, H., & Hagopian, W. (2007) · Reviews in Endocrine & Metabolic Disorders · doi:10.1007/s11154-006-9024-y · Cited by 183
Wilkin, T. J. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.97 · Cited by 158
Testing the Accelerator Hypothesis
Dabelea, D., D’Agostino, R. B., Mayer‐Davis, E. J., Pettitt, D. J., Imperatore, G., Dolan, L. M., Pihoker, C., Hillier, T. A., Marcovina, S. M., Linder, B. L., et al. (2006) · Diabetes Care · doi:10.2337/diacare.29.02.06.dc05-1339 · Cited by 126
Östman, J., Lönnberg, G., Arnqvist, H. J., Blohmé, G., Bolinder, J., Schnell, A. E., Eriksson, J. W., Gudbjörnsdottir, S., Sundkvist, G., & Nyström, L. (2008) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2007.01896.x · Cited by 147
Self-citationShu, X., Ji, J., Li, X., Sundquist, J., Sundquist, K., & Hemminki, K. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.03011.x · Cited by 121
Characteristics at diagnosis of type 1 diabetes in children younger than 6 years
Quinn, M., Fleischman, A., ROSNER, B. A., Nigrin, D. J., & Wolfsdorf, J. I. (2006) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2005.10.029 · Cited by 117
The incidence of diabetes among 0–34 year olds in Sweden: new data and better methods
Rawshani, A., Landin-Olsson, M., Svensson, A., Nyström, L., Arnqvist, H., Bolinder, J., & Gudbjörnsdottir, S. (2014) · Diabetologia · doi:10.1007/s00125-014-3225-9 · Cited by 116
“These studies were based on the DISS, which includes 15–34 year olds, and the SCDR, which includes patients aged 14 and younger [8, 9].”
MethodSelf-citationType 1 Diabetes and Autoimmune Thyroid Disease—The Genetic Link
Frommer, L., & Kahaly, G. J. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.618213 · Cited by 119
Trends in Incidence of Type 1 Diabetes Among Non-Hispanic White Youth in the U.S., 2002–2009
Lawrence, J. M., Imperatore, G., Dabelea, D., Mayer‐Davis, E. J., Linder, B. L., Saydah, S., KLINGENSMITH, G. J., Dolan, L. M., Standiford, D. A., Pihoker, C., et al. (2014) · Diabetes · doi:10.2337/db13-1891 · Cited by 110
Male–Female Differences in Diabetic Retinopathy?
Ozawa, G. Y., Bearse, M. A., & Adams, A. J. (2014) · Current Eye Research · doi:10.3109/02713683.2014.958500 · Cited by 107
“Figure adapted from Pundziute-Lycka et al.(16).”
BackgroundSvensson, M. K. E., Sundkvist, G., Arnqvist, H. J., Björk, E., Blohmé, G., Bolinder, J., Henricsson, M., Nyström, L., Torffvit, O., Waernbaum, I., et al. (2003) · Diabetes Care · doi:10.2337/diacare.26.10.2903 · Cited by 104
Self-citationMöllsten, A., Svensson, M. K. E., Waernbaum, I., Berhan, Y. T., Schön, S., Nyström, L., Arnqvist, H. J., Dahlquist, G. G., & for the Swedish Childhood Diabetes Study Group, T. D. I. S. I. S. (2010) · Diabetes · doi:10.2337/db09-1744 · Cited by 103
“Although the incidence of type 1 diabetes has increased in children, and onset of disease occurs at younger age (2,3), a decrease in incidence of diabetic nephropathy and a longer duration from onset of diabetes to diabetic nephropathy and ESRD has been reported from dedicated centers (4).”
BackgroundSelf-citationAir pollution as a potential contributor to the ‘epidemic’ of autoimmune disease
Ritz, S. A. (2009) · Medical Hypotheses · doi:10.1016/j.mehy.2009.07.033 · Cited by 102
Incidence of Type 1 Diabetes in Sweden Among Individuals Aged 0–34 Years, 1983–2007
Dahlquist, G. G., Nyström, L., Patterson, C. C., the Swedish Childhood Diabetes Study Group, & the Diabetes Incidence in Sweden Study Group (2011) · Diabetes Care · doi:10.2337/dc11-0056 · Cited by 102
“However, the proportion of cases in the DISS classified as type 1 diabetes has not significantly changed over time (4).”
BackgroundResultSelf-citationType 1 diabetes and polyglandular autoimmune syndrome: A review
Hansen, M. P. (2015) · World Journal of Diabetes · doi:10.4239/wjd.v6.i1.67 · Cited by 98
Glycemic and Risk Factor Control in Type 1 Diabetes
Eeg‐Olofsson, K., Cederholm, J., Nilsson, P. M., Guðbjörnsdóttir, S., & Eliasson, B. (2007) · Diabetes Care · doi:10.2337/dc06-1406 · Cited by 94
Spring harvest? Reflections on the rise of type 1 diabetes
Gale, E. A. M. (2005) · Diabetologia · doi:10.1007/s00125-005-0028-z · Cited by 90
Wennick, A., & Hallström, I. (2006) · Journal of Family Nursing · doi:10.1177/1074840706296724 · Cited by 88
“…Group, 2000; Freiesleben De Blasio, Bak, Pociot, Karlsen, & Nerup, 1999; Green, Sjolie, & Eshoj, 1998; Karvonen et al., 1993; A. Lernmark, 1999; Pundziute-Lycka et al., 2002), and due to the increasing incidence of younger age at diagnosis (Pundziute-Lycka et al., 2002), extensive demands are…”
BackgroundTrends in high-risk HLA susceptibility genes among Colorado youth with type 1 diabetes
Vehik, K., Hamman, R. F., Lezotte, D., Norris, J. M., Klingensmith, G. J., Rewers, M., & Dabelea, D. (2008) · Diabetes Care · doi:10.2337/dc07-2210 · Cited by 82
Redefining relationships and identity in young adults with type 1 diabetes
Sparud‐Lundin, C., Öhrn, I., & Danielson, E. (2009) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2009.05166.x · Cited by 82
“Young adults with diabetes face a number of challenges at the time for transition to adult life, a process becoming more common due to the shift of diabetes onset during childhood instead of in early adulthood (Pundziute-Lycka et al. 2002).”
BackgroundSvensson, J., Lyngaae-Jørgensen, A., Carstensen, B., Simonsen, L. B., Mortensen, H. B., & Danish Childhood Diabetes Registry (2008) · Pediatric Diabetes · doi:10.1111/j.1399-5448.2008.00483.x · Cited by 80
Puberty, Developmental Processes, and Health Interventions
Viner, R., Allen, N. B., & Patton, G. C. (2017) · World Bank, Washington, DC eBooks · doi:10.1596/978-1-4648-0423-6_ch9 · Cited by 83
The risk factors of ketoacidosis in children with newly diagnosed type 1 diabetes mellitus
Szypowska, A., & Skórka, A. (2010) · Pediatric Diabetes · doi:10.1111/j.1399-5448.2010.00689.x · Cited by 75
Zipris, D. (2009) · Clinical Immunology · doi:10.1016/j.clim.2008.12.011 · Cited by 75
Glycaemic control and diabetes care utilization in young adults with Type 1 diabetes1
Sparud‐Lundin, C., Öhrn, I., Danielson, E., & Forsander, G. (2008) · Diabetic Medicine · doi:10.1111/j.1464-5491.2008.02521.x · Cited by 74
Lamb, M. M., Yin, X., Zerbe, G. O., KLINGENSMITH, G. J., Dabelea, D., Fingerlin, T. E., Rewers, M., & Norris, J. M. (2009) · Diabetologia · doi:10.1007/s00125-009-1428-2 · Cited by 75
Age-Period-Cohort Analysis of 1990–2003 Incidence Time Trends of Childhood Diabetes in Italy
Bruno, G., Maule, M. M., Merletti, F., Novelli, G., Falorni, A., Iannilli, A., Iughetti, L., Altobelli, E., d’Annunzio, G., Piffer, S., et al. (2010) · Diabetes · doi:10.2337/db10-0151 · Cited by 74
Söderström, U., Åman, J., & Hjern, A. (2012) · Acta Paediatrica · doi:10.1111/j.1651-2227.2011.02410.x · Cited by 88
“In Sweden, this has been accompanied by a shift to a younger age at onset (4).”
BackgroundDiabetes: a growing epidemic of all ages.
Moore, P. A., Zgibor, J. C., & Dasanayake, A. P. (2003) · PubMed · Cited by 73
Age-Dependent Influences on the Origins of Autoimmune Diabetes
Leslie, R. D., & Castelli, M. D. (2004) · Diabetes · doi:10.2337/diabetes.53.12.3033 · Cited by 72
“In support of accelerated disease progression, the disease incidence rose in the young (age 0‐14 years) with a coincident fall later (15‐34 or 39 years) ( 27 ,28).”
BackgroundGenetic and perinatal factors as risk for childhood type 1 diabetes
Larsson, K., Larsson, H. E., Cedervall, E., Kockum, K., Neiderud, J., Sjöblad, S., Lindberg, B. A., Lernmark, B., Cilio, C., Ivarsson, S. A., et al. (2004) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.506 · Cited by 72
Increased Risk of Childhood Type 1 Diabetes in Children Born After 1985
Svensson, J., Carstensen, B., Mølbak, A. G., Christau, B., Mortensen, H. B., Nerup, J., Borch‐Johnsen, K., & the Danish Study Group of Diabetes in Childhood (DSBD) (2002) · Diabetes Care · doi:10.2337/diacare.25.12.2197 · Cited by 69
Continuous rise in incidence of childhood Type 1 diabetes in Germany
Ehehalt, S., Blumenstock, G., Willasch, A. M., Hub, R., Ranke, M. B., Neu, A., & for the DIARY‐study Group Baden‐Württemberg (2008) · Diabetic Medicine · doi:10.1111/j.1464-5491.2008.02450.x · Cited by 68
Derraik, J. G. B., Reed, P., Jefferies, C., Cutfield, S. W., Hofman, P. L., & Cutfield, W. S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032640 · Cited by 77
Diabetes Incidence in 0- to 14-Year Age-Group in Italy
Carle, F., Gesuita, R., Bruno, G., Coppa, G. V., Falorni, A., Lorini, R., Martinucci, M., Pozzilli, P., Prisco, F., Songini, M., et al. (2004) · Diabetes Care · doi:10.2337/diacare.27.12.2790 · Cited by 63
for the Swedish Better Diabetes Diagnosis Study Group, Carlsson, A., Kockum, I. S., Lindblad, B., Engleson, L., Nilsson, A. C., Forsander, G., Karlsson, A., Kernell, A., Ludvigsson, J., et al. (2011) · International Journal of Obesity · doi:10.1038/ijo.2011.122 · Cited by 61
Li, Z., Yang, N., He, L., Wang, J., Yang, Y., Ping, F., Xu, L., Zhang, H., Li, W., & Li, Y. (2024) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2024.21 · Cited by 66
“The age of onset of metabolic risk factors tended to be younger (35-36).”
Epidemiological Perspectives on Type 1 Diabetes in Childhood and Adolescence in Germany
Ehehalt, S., Dietz, K., Willasch, A. M., Neu, A., & for the Baden-Württemberg Diabetes Incidence Registry (DIARY) Group (2009) · Diabetes Care · doi:10.2337/dc09-1503 · Cited by 59
Galli, E., Härkönen, T., Sainio, M. T., Ustav, M., Toots, U., Urtti, A. O., Yliperttula, M. L., Lindahl, M., Knip, M., Saarma, M., et al. (2016) · Scientific Reports · doi:10.1038/srep29058 · Cited by 59
Pozzilli, P., Guglielmi, C., Pronina, E. A., & Petryaykina, E. E. (2007) · Pediatric Diabetes · doi:10.1111/j.1399-5448.2007.00338.x · Cited by 57
Pathogenesis of Type 1 Diabetes: Implications for Incidence Trends
Knip, M. (2011) · Hormone Research in Paediatrics · doi:10.1159/000329169 · Cited by 56
“Whether this is a population-wide increase or a consequence of decreasing average age at disease presentation is controversial. A recent Swedish study reported that there was no significant change in the overall incidence of T1D over a 16-year period in the Swedish population below the age of 35 years, but a shift tow…”
BackgroundGlutathione-s-transferase M1 and T1 polymorphisms and associations with type 1 diabetes age-at-onset
Bekris, L. M., Shephard, C., Peterson, M., Hoehna, J. L., Yserloo, B. V., Rutledge, E. A., Farin, F. M., Kavanagh, T. J., & Lernmark, Å. (2005) · Autoimmunity · doi:10.1080/08916930500407238 · Cited by 56
The emerging global epidemic of paediatric inflammatory bowel disease – causes and consequences
Malmborg, P., & Hildebrand, H. (2015) · Journal of Internal Medicine · doi:10.1111/joim.12413 · Cited by 55
Liu, C., Yuan, Y.-C., Guo, M.-N., Xin, Z., Chen, G.-J., Bentley, A. R., Hua, L., Zheng, J.-P., Ekoru, K., & Yang, J.-K. (2021) · Diabetes Care · doi:10.2337/dc21-0342 · Cited by 55
The Increasing Onset of Type 1 Diabetes in Children
Hummel, K., McFann, K., Realsen, J., Messer, L. H., KLINGENSMITH, G. J., & Chase, H. P. (2012) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2012.03.061 · Cited by 51
Samuelsson, U., Lindblad, B., Carlsson, A., Forsander, G., Ivarsson, S. A., Kockum, I. S., Lernmark, Å., Marcus, C., Ludvigsson, J., & Better Diabetes Diagnosis (BDD) study group (2012) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2365 · Cited by 50
“All factors mentioned previously may contribute to the less good metabolic control of girls with T1D, but are there differences also in disease process? Thus, we know that T1D is twice as common in boys as in girls after the age of 15 years [9], in contrast to other autoimmune diseases that tend to be more common in w…”
ResultPiedmont Study Group for Diabetes Epidemiology, Bruno, G., Novelli, G., Panero, F., Perotto, M., Monasterolo, F., Bona, G., Perino, A., Rabbone, I., Cavallo‐Perin, P., et al. (2009) · Diabetologia · doi:10.1007/s00125-009-1538-x · Cited by 48
“susceptible individuals rather than a true lifetime increasing risk of the disease has been suggested by the few studies that extended the recruitment of incident cases up to adults [ 4 , 5].”
BackgroundResultDemirbilek, H., Mehmet, N. Ö., & Baran, R. T. (2013) · Journal of Clinical Research in Pediatric Endocrinology · doi:10.4274/jcrpe.954 · Cited by 47
Cord blood islet autoantibodies and seasonal association with the type 1 diabetes high-risk genotype
Lynch, K. F., Lernmark, B., Merlo, J., Cilio, C., Ivarsson, S., Lernmark, Å., & for the Diabetes Prediction in Skåne (DiPiS) Study Group (2008) · Journal of Perinatology · doi:10.1038/sj.jp.7211912 · Cited by 47
Lamb, M. M., Yin, X., Barriga, K. J., Hoffman, M., Barón, A. E., Eisenbarth, G. S., Rewers, M., & Norris, J. M. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0886 · Cited by 46
Dahlquist, G. G., Pundziūtė-Lyckå, A., Nyström, L., & Groups, S. C. D. S. A. T. D. I. S. I. S. (. (2005) · Diabetologia · doi:10.1007/s00125-005-1759-6 · Cited by 46
“The completeness of the register varied between 86 and 97% (mean 91%) [ 7 ].”
InfluentialSelf-citationJoner, G., Stene, L. C., Sövik, O., & the Norwegian Childhood Diabetes Study Group (2004) · Diabetes Care · doi:10.2337/diacare.27.7.1618 · Cited by 45
Pundziūtė-Lyckå, A., Urbonaitė, B., Ostrauskas, R., Zalinkevicius, R., & Dahlquist, G. G. (2003) · Diabetes Care · doi:10.2337/diacare.26.3.671 · Cited by 42
Self-citationType 1 diabetes and associated autoimmune diseases
Frommer, L., & Kahaly, G. J. (2020) · World Journal of Diabetes · doi:10.4239/wjd.v11.i11.527 · Cited by 41
More Than 20 Years of Registration of Type 1 Diabetes in Sardinian Children
Bruno, G., Maule, M. M., Biggeri, A., Ledda, A., Mannu, C., Merletti, F., Songini, M., & the Sardinian Group for Diabetes Epidemiology (2013) · Diabetes · doi:10.2337/db12-1771 · Cited by 41
Gong, C., Meng, X., Jiang, Y., Wang, X., Cui, H., & Chen, X. (2014) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2014.0205 · Cited by 41
Schölin, A., Törn, C., Nyström, L., Berne, C., Arnqvist, H. J., Blohmé, G., Bolinder, J., Eriksson, J. W., Kockum, I. S., Landin‐Olsson, M., et al. (2004) · Diabetic Medicine · doi:10.1111/j.1464-5491.2004.01175.x · Cited by 41
Self-citationMoore, P. A., Zgibor, J. C., & Dasanayake, A. P. (2003) · The Journal of the American Dental Association · doi:10.14219/jada.archive.2003.0369 · Cited by 83
Rask, C., Evertsson, S., Telemo, E., & Wold, A. E. (2005) · Scandinavian Journal of Immunology · doi:10.1111/j.1365-3083.2005.01598.x · Cited by 40
Type 1 diabetes in Africa: an immunogenetic study in the Amhara of North-West Ethiopia
Balcha, S. A., Demisse, A. G., Mishra, R., Vartak, T., Cousminer, D. L., Hodge, K. M., Voight, B. F., Lorenz, K., Schwartz, S., Jerram, S. T., et al. (2020) · Diabetologia · doi:10.1007/s00125-020-05229-x · Cited by 41
Teeäär, T., Liivak, N., Heilman, K., Kool, P., Šor, R., Paal, M., Einberg, Ü., & Tillmann, V. (2009) · Pediatric Diabetes · doi:10.1111/j.1399-5448.2009.00535.x · Cited by 39
“This has been shown to be the case in some European countries, where an increase in childhood incidence was associated with a decrease in adult incidence (10, 11).”
BackgroundEising, S., Svensson, J., Skogstrand, K., Nilsson, A., Lynch, K. F., Andersen, P. S., Lernmark, Å., HOUGAARD, D. M., Pociot, F., Nørgaard‐Pedersen, B., et al. (2007) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.2007.00846.x · Cited by 38
Sella, T., Shoshan, A., Goren, I., Shalev, V., Blumenfeld, O., Laron, Z., & Chodick, G. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.03174.x · Cited by 37
Svensson, M. K. E., Tyrberg, M., Nyström, L., Arnqvist, H. J., Bolinder, J., Östman, J., Guðbjörnsdóttir, S., Landin‐Olsson, M., & Eriksson, J. W. (2014) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2574 · Cited by 36
“Since 1983, the DISS has aimed to register all newly diagnosed cases of diabetes, except gestational diabetes, in the age group 15–34 years [16].”
Self-citationFranke, B., Galloway, T. S., & Wilkin, T. J. (2005) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.554 · Cited by 36
“The Swedish study reported no change in the incidence of type 1 diabetes in the age group 0 to 34 over a 16year period, but the median age at diagnosis significantly decreased during this period [13].”
BackgroundHolmberg, H., Vaarala, O., Sadauskaitė – Kuehne, V., Ilonen, J., Padaiga, Ž., & Ludvigsson, J. (2006) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2005.10.022 · Cited by 35
Lindehammer, S. R., Larsson, K., Örtqvist, E., Carlsson, A., Cedervall, E., Cilio, C., Ivarsson, S. A., Jönsson, B., Larsson, H. E., Lynch, K. F., et al. (2008) · Acta Diabetologica · doi:10.1007/s00592-008-0048-5 · Cited by 35
“According to several studies in trends of incidence, the overall increase in Sweden at 0–34 years of age seems to have reached a plateau, concurrently as the onset of disease has shifted to younger ages [4].”
BackgroundSelf-citationStahl‐Pehe, A., Kamrath, C., Prinz, N., Kapellen, T. M., Menzel, U., Kordonouri, O., Schwab, K., Pozza, S. B., Rosenbauer, J., & Holl, R. W. (2022) · Journal of Diabetes · doi:10.1111/1753-0407.13339 · Cited by 33
Excess Cardiovascular Risk in Diabetic Women: A Case for Intensive Treatment
Recarti, C., Sep, S. J. S., Stehouwer, C. D. A., & Unger, T. (2015) · Current Hypertension Reports · doi:10.1007/s11906-015-0554-0 · Cited by 34
Chapter 5.2: Major public health problems — diabetes
Eliasson, M., & Boström, G. (2006) · Scandinavian Journal of Public Health · doi:10.1080/14034950600676883 · Cited by 33
“Since the disease starts at increasingly low ages, however, increasing numbers will contract it during childhood, instead of as young adults [6].”
BackgroundChildhood growth and age at diagnosis with Type 1 diabetes in Colorado young people
Vehik, K., Hamman, R. F., Lezotte, D. C., Norris, J. M., KLINGENSMITH, G. J., & Dabelea, D. (2009) · Diabetic Medicine · doi:10.1111/j.1464-5491.2009.02819.x · Cited by 32
Hussen, H. I., Persson, M., & Moradi, T. (2013) · BMJ Open · doi:10.1136/bmjopen-2013-003418 · Cited by 30
Metadata
- Authors
- and the Swedish Childhood Diabetes Study Group, Pundziute-Lyckå, A., Dahlquist, G., Nyström, L., Arnqvist, H., Björk, E., Blohmé, G., Bolinder, J., Eriksson, J., Sundkvist, G., & Östman, J.
- Affiliations
- Umeå University (SE)
- Linköping University (SE)
- Uppsala University Hospital (SE)
- Karolinska Institutet (SE)
- Skåne University Hospital (SE)
- Venue
- Diabetologia
- Published
- 2002-05-08
- Volume
- 45
- Issue
- 6
- Pages
- 783-791
- ISSN
- 0012-186X (ISSN-L)
- 1432-0428
- OpenAlex
- W1996624137
- Cited by
- 234
- References
- 40
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 4 · 2022: 1 · 2021: 3 · 2020: 4 · 2019: 5 · 2018: 5 · 2017: 7 · 2016: 9 · 2015: 10 · 2014: 13 · 2013: 12 · 2012: 12
- FWCI
- 8.22
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Diabetologia (publishedVersion)
- PubMed (publishedVersion)
- Lund University Publications (Lund University) (submittedVersion)
- Funders
- Medical Research Council
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- type 1 diabetes, incidence trends, age at diagnosis, pediatric diabetes, sex differences, Sweden, diabetes registry, cumulative incidence
- MeSH terms
- Adolescent, Adult, Child, Child, Preschool, Diabetes Mellitus, Type 1, Female, Humans, Infant, Male, Regression Analysis, Sex Characteristics, Sweden, Time Factors, Incidence, Poisson Distribution, Age of Onset, Age Distribution
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
