Apparent motion perception in patients with paranoid schizophrenia
Abstract
Impaired perceptual inference has been suggested to be at the core of positive symptoms in schizophrenia. Apparent motion (AM) is a visual illusion in which perceptual inference gives rise to the experience of a single object moving back and forth when two spatially separated objects are flashed in alternation. Here, we investigated the strength of AM perception in patients with paranoid schizophrenia. Patients were less susceptible to the illusion as indicated by a lower probability of motion perception at the individual's optimal presentation frequency for AM. In addition, the probability of AM perception was inversely related to delusional conviction in the patient group. These results suggest that schizophrenia may be associated with a reduced susceptibility to visual phenomena that commonly rely on perceptual inference.
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Resistance to the Apparent motion illusion in schizophrenia patients was attributed to their incapacity to correctly use top-down processes.
“Resistance to the illusion in schizophrenia patients was notably attributed to their incapacity to correctly use top-down processes in this situation (Sanders et al., 2013).”
From What visual illusions teach us about schizophrenia (2014) · cites this paper as Sanders et al., 2013
Studies have identified negative correlations between illusion susceptibility and the presence of positive symptoms in healthy and clinical populations.
“This assumption has strong support in studies that identified negative correlations between illusion susceptibility and the presence of positive symptoms in healthy (Bressan and Kramer, 2013) and clinical populations (Keane et al., 2013; Sanders et al., 2013).”
From What visual illusions teach us about schizophrenia (2014) · cites this paper as Sanders et al., 2013
Cites
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900 · see citing works
The Positive and Negative Syndrome Scale (PANSS) for schizophrenia.
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987) · Schizophrenia Bulletin · doi:10.1093/schbul/13.2.261 · Cited by 21,378 · see citing works
Rao, R. P. N., & Ballard, D. H. (1999) · Nature Neuroscience · doi:10.1038/4580 · Cited by 5,483 · see citing works
Abnormal neural oscillations and synchrony in schizophrenia
Uhlhaas, P. J., & Singer, W. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2774 · Cited by 2,120 · see citing works
Perceiving is believing: a Bayesian approach to explaining the positive symptoms of schizophrenia
Fletcher, P. C., & Frith, C. D. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2536 · Cited by 1,462 · see citing works
A free energy principle for the brain
Friston, K., Kilner, J., & Harrison, L. (2006) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2006.10.001 · Cited by 1,369 · see citing works
Hierarchical Organization of Human Cortical Networks in Health and Schizophrenia
Bassett, D. S., Bullmore, E. T., Verchinski, B. A., Mattay, V. S., Weinberger, D. R., & Meyer‐Lindenberg, A. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1929-08.2008 · Cited by 1,203 · see citing works
Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring
Stephan, K. E., Friston, K. J., & Frith, C. D. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbn176 · Cited by 1,134 · see citing works
Disrupted small-world networks in schizophrenia
Liu, Y., Liang, M., Zhou, Y., Yong He, A., Hao, Y., Song, M., Yu, C., Liu, H., Liu, Z., & Jiang, T. (2008) · Brain · doi:10.1093/brain/awn018 · Cited by 1,020 · see citing works
Brain States: Top-Down Influences in Sensory Processing
Gilbert, C. D., & Sigman, M. (2007) · Neuron · doi:10.1016/j.neuron.2007.05.019 · Cited by 936 · see citing works
Friston, K. J. (1998) · Schizophrenia Research · doi:10.1016/s0920-9964(97)00140-0 · Cited by 882 · see citing works
Synaptic plasticity and dysconnection in schizophrenia
Stephan, K. E., Baldeweg, T., & Friston, K. J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.10.005 · Cited by 841 · see citing works
Measuring Delusional Ideation: The 21-Item Peters et al. Delusions Inventory (PDI)
Peters, E., Joseph, S., Day, S., & Garety, P. (2004) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a007116 · Cited by 607 · see citing works
Reasoning in Deluded Schizophrenic and Paranoid Patients
Garety, P. A., HEMSLEY, D. R., & Wessely, S. C. (1991) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199104000-00003 · Cited by 602 · see citing works
Knowledge in perception and illusion
Gregory, R. L. (1997) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.1997.0095 · Cited by 498 · see citing works
Small‐world properties of nonlinear brain activity in schizophrenia
Rubinov, M., Knock, S. A., Stam, C. J., Micheloyannis, S., Harris, A. W. F., Williams, L. M., & Breakspear, M. J. (2007) · Human Brain Mapping · doi:10.1002/hbm.20517 · Cited by 458 · see citing works
Small-world networks and disturbed functional connectivity in schizophrenia
Micheloyannis, S., Pachou, E., Stam, C. J., Breakspear, M. J., Bitsios, P., Vourkas, M., Erimaki, S., & Zervakis, M. E. (2006) · Schizophrenia Research · doi:10.1016/j.schres.2006.06.028 · Cited by 435 · see citing works
Towards a mathematical theory of cortical micro-circuits
George, D., & Hawkins, J. (2009) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000532 · Cited by 404 · see citing works
Toward a neurobiology of delusions
Corlett, P. R., Taylor, J. R., Wang, X.-J., Fletcher, P. C., & Krystal, J. H. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.06.007 · Cited by 394 · see citing works
The d2 Test of Attention: Construct validity and extensions in scoring techniques
Bates, M. E., & Lemay, E. P. (2004) · Journal of the International Neuropsychological Society · doi:10.1017/s135561770410307x · Cited by 356 · see citing works
Silverstein, S. M., & Keane, B. P. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr052 · Cited by 284 · see citing works
Silverstein, S. M., Kovács, I., Corry, R., & Valone, C. (2000) · Schizophrenia Research · doi:10.1016/s0920-9964(99)00180-2 · Cited by 240 · see citing works
Weak suppression of visual context in chronic schizophrenia
Dakin, S., Carlin, P., & Hemsley, D. (2005) · Current Biology · doi:10.1016/j.cub.2005.10.015 · Cited by 227 · see citing works
Emrich, H. M., Leweke, F. M., & Schneider, U. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(96)00426-1 · Cited by 226 · see citing works
Motion perception in schizophrenia
Chen, Y., Palafox, G. P., Nakayama, K., Levy, D. L., Matthysse, S., & Holzman, P. S. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.2.149 · Cited by 225 · see citing works
Reduced prefrontal-parietal effective connectivity and working memory deficits in schizophrenia
Deserno, L., Sterzer, P., Wüstenberg, T., Heinz, A., & Schlagenhauf, F. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.3405-11.2012 · Cited by 214 · see citing works
Self-citationDima, D., Roiser, J. P., Dietrich, D. E., Bonnemann, C., Lanfermann, H., Emrich, H. M., & Dillo, W. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.03.033 · Cited by 192 · see citing works
Processing of global, but not local, motion direction is deficient in schizophrenia
Chen, Y. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(02)00222-0 · Cited by 183 · see citing works
Neural correlates of the contents of visual awareness in humans
Rees, G. E. (2007) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2007.2094 · Cited by 162 · see citing works
Primary visual cortex activation on the path of apparent motion is mediated by feedback from hMT+/V5
Sterzer, P., Haynes, J.-D., & Rees, G. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.05.029 · Cited by 156 · see citing works
Self-citationPerceptual grouping in disorganized schizophrenia
Uhlhaas, P. J., Phillips, W. A., Mitchell, G., & Silverstein, S. M. (2006) · Psychiatry Research · doi:10.1016/j.psychres.2005.10.016 · Cited by 149 · see citing works
The development of a cognitive model of schizophrenia: Placing it in context
Hemsley, D. R. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.12.008 · Cited by 141 · see citing works
Somatosensory evoked potentials during a rubber-hand illusion in schizophrenia
Peled, A., Pressman, A., Geva, A. B., & Modai, I. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(03)00057-4 · Cited by 132 · see citing works
Visual binding abilities in the initial and advanced stages of schizophrenia
Parnas, J., Vianin, P., Sæbye, D., Jansson, L., Larsen, A. V., & Bovet, P. (2001) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2001.00160.x · Cited by 129 · see citing works
Impaired top-down processes in schizophrenia: a DCM study of ERPs
Dima, D., Dietrich, D. E., Dillo, W., & Emrich, H. M. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.12.086 · Cited by 122 · see citing works
Diminished Orientation-Specific Surround Suppression of Visual Processing in Schizophrenia
Yoon, J. H., Rokem, A., Silver, M. A., Minzenberg, M., Ursu, S., Ragland, J. D., & Carter, C. S. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp064 · Cited by 114 · see citing works
Reduced binocular depth inversion in schizophrenic patients
Schneider, U., Borsutzky, M., Seifert, J., Leweke, F. M., Huber, T. J., Rollnik, J. D., & Emrich, H. M. (2002) · Schizophrenia Research · doi:10.1016/s0920-9964(00)00172-9 · Cited by 108 · see citing works
Stroboscopic Movement Based on Perceptual Intelligence
Sigman, E., & Rock, I. (1974) · Perception · doi:10.1068/p030009 · Cited by 105 · see citing works
Kim, J., Park, S., & Blake, R. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019971 · Cited by 97 · see citing works
Yellott, J. I. (1981) · Scientific American · doi:10.1038/scientificamerican0781-148 · Cited by 73 · see citing works
Hoffman, R. E., Woods, S. W., Hawkins, K. A., Pittman, B. P., Tohen, M. F., Preda, A., Breier, A. F., Glist, J., Addington, J., Perkins, D. O., et al. (2007) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.106.031195 · Cited by 71 · see citing works
Compromised late-stage motion processing in schizophrenia
Chen, Y., Levy, D. L., Sheremata, S., & Holzman, P. S. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.12.024 · Cited by 70 · see citing works
Information Processing in Schizophrenia and Bipolar Disorder: A Discriminant Analysis
Tam, W.-C. C., Sewell, K. W., & Deng, H.-C. (1998) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199810000-00002 · Cited by 66 · see citing works
Chinese and Americans see opposite apparent motions in a Chinese character
Tse, P. U., & Cavanagh, P. (2000) · Cognition · doi:10.1016/s0010-0277(99)00065-7 · Cited by 64 · see citing works
The Timing of Feedback to Early Visual Cortex in the Perception of Long-Range Apparent Motion
Wibral, M., Bledowski, C., Kohler, A., Singer, W., & Muckli, L. F. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn192 · Cited by 63 · see citing works
Cortical Dynamics Subserving Visual Apparent Motion
Ahmed, B., Hanazawaᎂᎂ, A., Undeman, C., Eriksson, D., Valentiniene, S., & Roland, P. E. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn038 · Cited by 61 · see citing works
The method of constant stimuli is efficient
Simpson, W. A. (1988) · Perception & Psychophysics · doi:10.3758/bf03210427 · Cited by 57 · see citing works
CHEN, Y., Grossman, E. D., Bidwell, L. C., Yurgelun-Todd, D. A., Gruber, S. A., Levy, D. L., NAKAYAMA, K., & Holzman, P. S. (2008) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/cabn.8.3.293 · Cited by 54 · see citing works
A cognitive model for schizophrenia and its possible neural basis
Hemsley, D. R. (1994) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1994.tb05895.x · Cited by 50 · see citing works
Molina, V., Galindo, G., Cortés, B., de Herrera, A. G. S., Ledo, A., Sanz, J., Montes, C., & Hernandez-Tamames, J. A. (2010) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-010-0183-1 · Cited by 43 · see citing works
Visual Context Processing Deficits in Schizophrenia: Effects of Deafness and Disorganization
Horton, H. K., & Silverstein, S. M. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr055 · Cited by 42 · see citing works
Lencer, R., Keedy, S., Reilly, J. L., McDonough, B. E., Harris, M. S. H., Sprenger, A., & Sweeney, J. A. (2011) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2011.06.011 · Cited by 37 · see citing works
Optimal inference explains the perceptual coherence of visual motion stimuli
Hedges, J., Stocker, A. A., & Simoncelli, E. P. (2011) · Journal of Vision · doi:10.1167/11.6.14 · Cited by 35 · see citing works
Wang, J., Brown, R., Dobkins, K. R., McDowell, J. E., & Clementz, B. A. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp243 · Cited by 35 · see citing works
The perception of real and illusory motion in schizophrenia
Crawford, T. J., Hamm, J. P., Kean, M., Schmechtig, A., Kumari, V., Anilkumar, A. P., & Ettinger, U. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2010.06.027 · Cited by 32 · see citing works
Reduced P300 and P600 amplitude in the hollow-mask illusion in patients with schizophrenia
Dima, D., Dillo, W., Bonnemann, C., Emrich, H. M., & Dietrich, D. E. (2011) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2010.09.015 · Cited by 30 · see citing works
The Miiller-Lyer Illusion as a Tool for Schizophrenia Screening
Pessoa, V. F., Monge-Fuentes, V., Simon, C. Y., Suganuma, E., & Tavares, M. C. H. (2008) · Reviews in the Neurosciences · doi:10.1515/revneuro.2008.19.2-3.91 · Cited by 27 · see citing works
Cerebral connectivity and psychotic personality traits
Volpe, U., Federspiel, A., Mucci, A., Dierks, T., Frank, A., Wahlund, L., Galderisi, S., & Maj, M. (2008) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-007-0796-1 · Cited by 25 · see citing works
The Müller-Lyer Illusion in Schizophrenic Patients
Weckowicz, T. E., & Witney, G. (1960) · Journal of Mental Science · doi:10.1192/bjp.106.444.1002 · Cited by 24 · see citing works
Cognitive abnormalities and schizophrenic symptoms
Hemsley, D. R. (1992) · Psychological Medicine · doi:10.1017/s003329170003840x · Cited by 23 · see citing works
A further study of the perception of apparent motion by schizophrenics.
Saucer, R. T. (1958) · Journal of Consulting Psychology · doi:10.1037/h0042362 · Cited by 18 · see citing works
Perception of apparent motion in organics and schizophrenics.
Saucer, R. T., & Deabler, H. L. (1956) · Journal of Consulting Psychology · doi:10.1037/h0040864 · Cited by 16 · see citing works
The Oppel-Kundt and the Müller-Lyer Illusions among Schizophrenics
Letourneau, J. E. (1974) · Perceptual and Motor Skills · doi:10.2466/pms.1974.39.2.775 · Cited by 15 · see citing works
Perception of Apparent Motion and Degree of Mental Pathology
Chambers, J. L., & Wilson, W. T. (1968) · Perceptual and Motor Skills · doi:10.2466/pms.1968.26.3.855 · Cited by 11 · see citing works
Detection of visual events along the apparent motion trace in patients with paranoid schizophrenia
Sanders, L. L. O., Muckli, L. F., de Millas, W., Lautenschlager, M. M., Heinz, A., Kathmann, N., & Sterzer, P. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2012.03.006 · Cited by 10 · see citing works
Self-citationChlorpromazine and apparent motion perception by schizophrenics.
Saucer, R. T. (1959) · Journal of Consulting Psychology · doi:10.1037/h0041208 · Cited by 6 · see citing works
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- Authors
- Sanders, L. L. O., de Millas, W., Heinz, A., Kathmann, N., & Sterzer, P.
- Affiliations
- Charité – Universitätsmedizin Berlin (DE)
- Humboldt-Universität zu Berlin (DE)
- Corresponding author
- Sanders, Lia Lira Olivier
- Venue
- European Archives of Psychiatry and Clinical Neuroscience
- Published
- 2012-08-05
- Volume
- 263
- Issue
- 3
- Pages
- 233-239
- ISSN
- 0003-9373 (ISSN-L)
- 0940-1334
- 1433-8491
- OpenAlex
- W2148730678
- Cited by
- 22
- References
- 66
- Citations by year
- 2024: 2 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 2 · 2016: 2 · 2015: 1 · 2014: 1 · 2013: 3
- FWCI
- 1.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- European Archives of Psychiatry and Clinical Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hallucinations in medical conditions
- Keywords
- apparent motion, paranoid schizophrenia, perceptual inference, optical illusions, delusional conviction, positive symptoms, motion perception
- MeSH terms
- Adult, Attention, Female, Fixation, Ocular, Humans, Male, Middle Aged, Motion Perception, Perceptual Disorders, Photic Stimulation, Psychiatric Status Rating Scales, Schizophrenia, Paranoid, Statistics as Topic, Young Adult
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