Affective disorders in the aftermath of miscarriage: A comprehensive review
Abstract
We review the research literature regarding affective symptomatology and disorders following miscarriage, with an emphasis on controlled studies and those that have been published since the last review article in 1996. The current review draws a sharp distinction between controlled and uncontrolled designs and clarifies the proper inferences that may be drawn from each, as only with an appropriate comparison group can it be determined whether the affective reactions following miscarriage are a specific consequence of the reproductive loss or of other life events common in women of reproductive age. In addition to providing an update of the literature on depression in the aftermath of miscarriage and associated risk factors, we also discuss reproductive loss in the context of attachment theory and grief, and present information on topics that were not covered extensively (or at all) by prior reviews, such as issues related to a pregnancy subsequent to miscarriage and the impact of miscarriage on the partners of miscarrying women. In the final section, treatment options relevant to miscarriage are presented.
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Some research in psychology queries a link between elapsed gestational time and increased feelings of bereavement.
“We also note that some research in psychology queries a link between elapsed gestational time and increased feelings of bereavement (Jaffe & Diamond, 2010; Klier et al., 2002)”
From Further Hierarchies of Loss: Tracking Relationality in Pregnancy Loss Experiences (2025) · cites this paper as Klier et al., 2002
Studies evaluating the association between length of gestation and level of distress after perinatal loss could not find an increase in psychological distress with higher gestational age.
“Contrary to these findings, however, are a number of studies have evaluated the association between length of gestation and level of distress after perinatal loss, and could not find an increase in psychological distress with higher gestational age.23,34”
From Complicated grief after perinatal loss (2012) · cites this paper as [23]
The more the mother has experienced or comprehended the reality of the baby, the higher the level of grief.
“It is thought, therefore, that the more the mother has experienced or comprehended the reality of the baby the higher the level of grief.23”
From Complicated grief after perinatal loss (2012) · cites this paper as [23]
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- Authors
- Klier, C. M., Geller, P. A., & Ritsher, J. B.
- Affiliations
- University of Vienna (AT)
- Drexel University (US)
- United States Department of Veterans Affairs (US)
- Venue
- Archives of Women's Mental Health
- Published
- 2002-12-01
- Volume
- 5
- Issue
- 4
- Pages
- 129-149
- ISSN
- 1434-1816 (ISSN-L)
- OpenAlex
- W1970087565
- Cited by
- 176
- References
- 123
- Citations by year
- 2026: 6 · 2025: 4 · 2024: 6 · 2023: 21 · 2022: 7 · 2021: 4 · 2020: 9 · 2019: 4 · 2018: 4 · 2017: 11 · 2016: 9 · 2015: 8 · 2014: 10 · 2013: 10 · 2012: 7
- FWCI
- 3.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Archives of Women s Mental Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Clinical Psychology › Grief, Bereavement, and Mental Health
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Keywords
- miscarriage, mood disorders, depression, reproductive losses, grief, attachment theory, subsequent pregnancy, risk factors, treatment options, women of reproductive age
- MeSH terms
- Abortion, Spontaneous, Female, Humans, Object Attachment, Pregnancy, Pregnancy Outcome, Mood Disorders
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