Functional foods, herbs and nutraceuticals: towards biochemical mechanisms of healthy aging

Oxidants, antioxidants, and the degenerative diseases of aging.

Ames, B. N., Shigenaga, M. K., & Hagen, T. M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.17.7915 · Cited by 5,958 · see citing works

The Bcl-2 Protein Family: Arbiters of Cell Survival

Adams, J. M., & Cory, S. (1998) · Science · doi:10.1126/science.281.5381.1322 · Cited by 5,303 · see citing works

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

Yang, J., Liu, X., Bhalla, K. N., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T.-I., Jones, D. P., & Wang, X. (1997) · Science · doi:10.1126/science.275.5303.1129 · Cited by 4,913 · see citing works

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

Kluck, R. M., Bossy‐Wetzel, E., Green, D. R., & Newmeyer, D. D. (1997) · Science · doi:10.1126/science.275.5303.1132 · Cited by 4,715 · see citing works

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Howitz, K. T., Bitterman, K. J., Cohen, H. Y., Lamming, D. W., Lavu, S., Wood, J. G., Zipkin, R. E., Chung, P., Kisielewski, A., Zhang, L.-L., et al. (2003) · Nature · doi:10.1038/nature01960 · Cited by 3,796 · see citing works

Neurodegenerative diseases and oxidative stress

Barnham, K. J., Masters, C. L., & Bush, A. I. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1330 · Cited by 3,683 · see citing works

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

Kane, D. J., Sarafian, T. A., Anton, R., Hahn, H., Gralla, E. B., Valentine, J. S., Örd, T., & Bredesen, D. E. (1993) · Science · doi:10.1126/science.8235659 · Cited by 1,671 · see citing works

A Matter of Life and Cell Death

Evan, G. I., & Littlewood, T. D. (1998) · Science · doi:10.1126/science.281.5381.1317 · Cited by 1,515 · see citing works

Selective Targeting of a Redox-active Ubiquinone to Mitochondria within Cells

Kelso, G. F., Porteous, C. M., Coulter, C. V., Hughes, G., Porteous, W. K., Ledgerwood, E. C., Smith, R. A. J., & Murphy, M. P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009093200 · Cited by 1,091 · see citing works

Oxidative stress in Alzheimer’s disease

Smith, M. A., Rottkamp, C. A., Nunomura, A., Raina, A. K., & Perry, G. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/s0925-4439(00)00040-5 · Cited by 895 · see citing works

The central executioners of apoptosis: caspases or mitochondria?

Green, D. R., & Kroemer, G. (1998) · Trends in Cell Biology · doi:10.1016/s0962-8924(98)01273-2 · Cited by 775 · see citing works

Aging and resistance to oxidative damage in Caenorhabditis elegans.

Larsen, P. L. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.19.8905 · Cited by 722 · see citing works

Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols

Yang, G. (1998) · Carcinogenesis · doi:10.1093/carcin/19.4.611 · Cited by 674 · see citing works

Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study

Hu, F. B., Stampfer, M. J., Manson, J. E., Rimm, E. B., Colditz, G. A., Rosner, B. A., Speizer, F. E., Hennekens, C. H., & Willett, W. C. (1998) · BMJ · doi:10.1136/bmj.317.7169.1341 · Cited by 597 · see citing works

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

Estévez, A. G., Crow, J. P., Sampson, J. B., Reiter, C., Zhuang, Y., Richardson, G. J., Tarpey, M. M., Barbeito, L., & Beckman, J. S. (1999) · Science · doi:10.1126/science.286.5449.2498 · Cited by 596 · see citing works

Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study

McKeown, N. M., Meigs, J. B., Liu, S., Wilson, P. W., & Jacques, P. F. (2002) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.2.390 · Cited by 574 · see citing works

Coenzyme Q ₁₀ administration increases brain mitochondrial concentrations and exerts neuroprotective effects

Matthews, R. T., Yang, L., Browne, S., Baik, M., & Beal, M. F. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.15.8892 · Cited by 557 · see citing works

Short- and Long-Term Black Tea Consumption Reverses Endothelial Dysfunction in Patients With Coronary Artery Disease

Duffy, S. J., Keaney, J. F., HOLBROOK, M. M., Gokce, N., Swerdloff, P. L., Frei, B. B., & Vita, J. A. (2001) · Circulation · doi:10.1161/01.cir.104.2.151 · Cited by 552 · see citing works

Increased mitochondrial oxidative stress in the Sod2 (+/−) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis

Kokoszka, J. E., Coskun, P. E., Esposito, L., & Wallace, D. C. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.051627098 · Cited by 488 · see citing works

Fatty Acid Oxidation Disorders

Rinaldo, P., Matern, D., & Bennett, M. J. (2002) · Annual Review of Physiology · doi:10.1146/annurev.physiol.64.082201.154705 · Cited by 483 · see citing works

Polyphenol tannic acid inhibits hydroxyl radical formation from Fenton reaction by complexing ferrous ions1This study is dedicated to the memory of Botany Professor Luiz F.G. Labouriau (1921–1996).1

Lopes, G. K. B., Schulman, H. M., & Hermes-Lima, M. (1999) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(99)00117-8 · Cited by 476 · see citing works

Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats

Duarte, J., Pérez‐Palencia, R., Vargas, F., Ocete, M. A., Pérez‐Vizcaíno, F., Zarzuelo, A., & Tamargo, J. L. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0704064 · Cited by 464 · see citing works

The Risk–Benefit Profile of Commonly Used Herbal Therapies: Ginkgo, St. John's Wort, Ginseng, Echinacea, Saw Palmetto, and Kava

Ernst, E. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-136-1-200201010-00010 · Cited by 460 · see citing works

Walnut Polyphenolics Inhibit In Vitro Human Plasma and LDL Oxidation

Anderson, K. J., Teuber, S. S., Gobeille, A., Cremin, P., Waterhouse, A. L., & Steinberg, F. M. (2001) · Journal of Nutrition · doi:10.1093/jn/131.11.2837 · Cited by 446 · see citing works

Progress in Cancer Chemoprevention: Development of Diet-Derived Chemopreventive Agents

Kelloff, G. J., Crowell, J. A., Steele, V. E., Lubet, R. A., Malone, W. A., Boone, C. W., Kopelovich, L., Hawk, E. T., Lieberman, R., Lawrence, J. A., et al. (2000) · Journal of Nutrition · doi:10.1093/jn/130.2.467s · Cited by 441 · see citing works

A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects

Youdim, K. A., & Joseph, J. A. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00510-4 · Cited by 434 · see citing works

Tomato lycopene and low density lipoprotein oxidation: A human dietary intervention study

Agarwal, S., & Rao, A. V. (1998) · Lipids · doi:10.1007/s11745-998-0295-6 · Cited by 430 · see citing works

The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties

Moosmann, B., & Behl, C. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.8867 · Cited by 411 · see citing works

Dietary Carotenoids and Vitamins A, C, and E and Risk of Breast Cancer

Zhang, S., Hunter, D. J., Forman, M. R., ROSNER, B. A., Speizer, F. E., Colditz, G. A., Manson, J. E., Hankinson, S. E., & Willett, W. C. (1999) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/91.6.547 · Cited by 390 · see citing works

The ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by β‐amyloid

Bastianetto, S., Ramassamy, C., Doré, S., Christen, Y., Poirier, J., & Quirion, R. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00069.x · Cited by 378 · see citing works

Dose Response of Almonds on Coronary Heart Disease Risk Factors: Blood Lipids, Oxidized Low-Density Lipoproteins, Lipoprotein(a), Homocysteine, and Pulmonary Nitric Oxide

Jenkins, D. J. A., Kendall, C. W. C., Marchie, A., Parker, T. L., Connelly, P. W., Qian, W., Haight, J. S. J., Faulkner, D. A., Vidgen, E., Lapsley, K. G., et al. (2002) · Circulation · doi:10.1161/01.cir.0000028421.91733.20 · Cited by 378 · see citing works

Tea Catechins Prevent the Development of Atherosclerosis in Apoprotein E–Deficient Mice

Miura, Y., Chiba, T., Miura, S., Tomita, I., Koizumi, H., Umegaki, K., Hara, Y., Ikeda, M., & Tomita, T. (2001) · Journal of Nutrition · doi:10.1093/jn/131.1.27 · Cited by 321 · see citing works

Effects of high- and low-isoflavone soyfoods on blood lipids, oxidized LDL, homocysteine, and blood pressure in hyperlipidemic men and women

Jenkins, D. J. A., Kendall, C. W. C., Jackson, C. C., Connelly, P. W., Parker, T. L., Faulkner, D. A., Vidgen, E., Cunnane, S. C., Leiter, L. A., & Josse, R. G. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.2.365 · Cited by 310 · see citing works

Plasma antioxidants and longevity: a study on healthy centenarians

Mecocci, P., Polidori, M. C., Troiano, L., Cherubini, A., Cecchetti, R., Pini, G., Straatman, M., Monti, D., Stahl, W., Sies, H., et al. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00246-x · Cited by 306 · see citing works

Isoprenoids Suppress the Growth of Murine B16 Melanomas In Vitro and In Vivo

He, L., Mo, H., Hadisusilo, S., Qureshi, A. A., & Elson, C. E. (1997) · Journal of Nutrition · doi:10.1093/jn/127.5.668 · Cited by 290 · see citing works

Mediterranean diet and longevity

Trichopoulou, A., & Vasilopoulou, E. (2000) · British Journal Of Nutrition · doi:10.1079/096582197388554 · Cited by 284 · see citing works

Establishing the Significance and Optimal Intake of Dietary Antioxidants: The Biomarker Concept

Halliwell, B. B. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1999.tb06933.x · Cited by 281 · see citing works

Impairment of Endothelial Functions by Acute Hyperhomocysteinemia and Reversal by Antioxidant Vitamins

Nappo, F. (1999) · JAMA · doi:10.1001/jama.281.22.2113 · Cited by 270 · see citing works

Low Mitochondrial Free Radical Production Per Unit O2Consumption Can Explain the Simultaneous Presence of High Longevity and High Aerobic Metabolic Rate in Birds

Barja, G., Cadenas, S., Rojas, C., Pérez‐Campo, R., & Lopez‐Torres, M. (1994) · Free Radical Research · doi:10.3109/10715769409056584 · Cited by 267 · see citing works

Impaired Homocysteine Metabolism and Atherothrombotic Disease

Durand, P., Prost, M., Loreau, N., Lussier‐Cacan, S., & Blache, D. (2001) · Laboratory Investigation · doi:10.1038/labinvest.3780275 · Cited by 262 · see citing works

Cardiac reperfusion injury: Aging, lipid peroxidation, and mitochondrial dysfunction

Lucas, D. T., & Szweda, L. I. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.2.510 · Cited by 254 · see citing works

Acetyl- l -carnitine fed to old rats partially restores mitochondrial function and ambulatory activity

Hagen, T. M., Ingersoll, R. T., Wehr, C. M., Lykkesfeldt, J., Vinarsky, V., Bartholomew, J. C., Song, M. H., & Ames, B. N. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.16.9562 · Cited by 252 · see citing works

Mechanisms of Action of Antioxidants as Exemplified in Vegetables, Tomatoes and Tea

Weisburger, J. H. (1999) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(99)00086-1 · Cited by 244 · see citing works

Double Blind Study of Melatonin Effects on the Sleep-wake Rhythm, Cognitive and Non-cognitive Functions in Alzheimer Type Dementia

Asayama, K., Yamadera, H., Ito, T., Suzuki, H., Kudo, Y., & Endo, S. (2003) · Journal of Nippon Medical School · doi:10.1272/jnms.70.334 · Cited by 242 · see citing works

Comparison of mitochondrial pro-oxidant generation and anti-oxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential

Ku, H., & Sohal, R. S. (1993) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(93)90132-b · Cited by 240 · see citing works

Simultaneous Overexpression of Copper- and Zinc-containing Superoxide Dismutase and Catalase Retards Age-related Oxidative Damage and Increases Metabolic Potential in Drosophila melanogaster

Sohal, R. S., Agarwal, A., Agarwal, S., & Orr, W. C. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.26.15671 · Cited by 239 · see citing works

Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals

Pamplona, R., Portero‐Otín, M., Riba, D., Ruiz, C., Prat, J., Bellmunt, M. J., & Barja, G. (1998) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32497-4 · Cited by 239 · see citing works

Molecular Mechanisms of c-Jun N-terminal Kinase-mediated Apoptosis Induced by Anticarcinogenic Isothiocyanates

Chen, Y., Wang, W., Kong, A.-N. T., & Tan, T. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.3.1769 · Cited by 237 · see citing works

The in vivo neuromodulatory effects of the herbal medicine ginkgo biloba

Watanabe, C. M. H., Wolffram, S., Ader, P., Rimbach, G. H., Packer, L., Maguire, J. J., Schultz, P. G., & Gohil, K. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111126298 · Cited by 234 · see citing works

Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status

Nesaretnam, K., Stephen, R., Dils, R., & Darbre, P. D. (1998) · Lipids · doi:10.1007/s11745-998-0229-3 · Cited by 231 · see citing works

Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson’s disease

Merad-Boudia, M., Nicole, A., Santiard-Baron, D., Saillé, C., & Ceballos-Picot, I. (1998) · Biochemical Pharmacology · doi:10.1016/s0006-2952(97)00647-3 · Cited by 227 · see citing works

The Ginkgo biloba Extract (EGb 761) Protects and Rescues Hippocampal Cells Against Nitric Oxide‐Induced Toxicity

Bastianetto, S., Zheng, W., & Quirion, R. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0742268.x · Cited by 222 · see citing works

Fruits and Vegetables Increase Plasma Carotenoids and Vitamins and Decrease Homocysteine in Humans

Broekmans, W. M. R., Klöpping-Ketelaars, I. A. A., Schuurman, C. R. W. C., Verhagen, H., van den Berg, H., Kok, F. J., & van Poppel, G. (2000) · Journal of Nutrition · doi:10.1093/jn/130.6.1578 · Cited by 218 · see citing works

Metal Chelation as a Potential Therapy for Alzheimer's Disease

Cuajungco, M. P., Faget, K. Y., Huang, X., Tanzi, R. E., & Bush, A. I. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06938.x · Cited by 215 · see citing works

Biochemical pharmacology of functional foods and prevention of chronic diseases of aging

Ferrari, C. K. B., & Torres, E. A. F. S. (2003) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(03)00032-5 · Cited by 211 · see citing works

An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice

Mansouri, A., Gaou, I., de Kerguenec, C., Amsellem, S., Haouzi, D., Berson, A., Moreau, A., Feldmann, G., Lettéron, P., Pessayre, D., et al. (1999) · Gastroenterology · doi:10.1016/s0016-5085(99)70566-4 · Cited by 208 · see citing works

Ipriflavone in the Treatment of Postmenopausal Osteoporosis A Randomized Controlled Trial

Alexandersen, P. (2001) · JAMA · doi:10.1001/jama.285.11.1482 · Cited by 204 · see citing works

Oxidants and antioxidants in atherogenesis: an appraisal

Parthasarathy, S., Santanam, N., Ramachandran, S., & Meilhac, O. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32089-7 · Cited by 194 · see citing works

Caloric Restriction and Incidence of Breast Cancer

Michels, K. B. (2004) · JAMA · doi:10.1001/jama.291.10.1226 · Cited by 185 · see citing works

Fish Oil Blocks Azoxymethane-Induced Rat Colon Tumorigenesis by Increasing Cell Differentiation and Apoptosis Rather Than Decreasing Cell Proliferation

Chang, W., Chapkin, R. S., & Lupton, J. R. (1998) · Journal of Nutrition · doi:10.1093/jn/128.3.491 · Cited by 185 · see citing works

Superoxide Dismutase 1 Knock-down Induces Senescence in Human Fibroblasts

Blander, G., de Oliveira, R. M., Conboy, C. M., Haigis, M., & Guarente, L. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307146200 · Cited by 183 · see citing works

Oxidative Stress Developed During the Reperfusion of Ischemic Myocardium Induces Apoptosis

Maulik, N., Yoshida, T., & Das, D. K. (1998) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(97)00388-2 · Cited by 181 · see citing works

Effects of Soy Phytoestrogens Genistein and Daidzein on Breast Cancer Growth

de Lemos, M. L. (2001) · Annals of Pharmacotherapy · doi:10.1345/aph.10257 · Cited by 166 · see citing works

PUFA and aging modulate cardiac mitochondrial membrane lipid composition and Ca2+activation of PDH

Pepe, S., Tsuchiya, N., Lakatta, E. G., & Hansford, R. G. (1999) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1999.276.1.h149 · Cited by 161 · see citing works

Lipid peroxidationin vivo

Witting, L. A. (1965) · Journal of the American Oil Chemists Society · doi:10.1007/bf02632443 · Cited by 159 · see citing works

Oxidative Stress, Mitochondrial Dysfunction, and Epilepsy

Patel, M. N. (2002) · Free Radical Research · doi:10.1080/1071576021000016391 · Cited by 152 · see citing works

Extra-Virgin Olive Oil Increases the Resistance of LDL to Oxidation More than Refined Olive Oil in Free-Living Men with Peripheral Vascular Disease

Ramírez-Tortosa, M. C., Urbano, G., López-Jurado, M., Nestares, T., Gómez, M. C., MIR, A., Ros, E., Mataix, J., & Gil, Á. (1999) · Journal of Nutrition · doi:10.1093/jn/129.12.2177 · Cited by 151 · see citing works

Isoflavone Aglycone–Rich Extract without Soy Protein Attenuates Atherosclerosis Development in Cholesterol-Fed Rabbits

Yamakoshi, J., Izumi, T., Tobe, K., Saito, M., Kataoka, S., Obata, A., Kikuchi, M., & Piskuła, M. K. (2000) · Journal of Nutrition · doi:10.1093/jn/130.8.1887 · Cited by 150 · see citing works

The Risk–Benefit Profile of Commonly Used Herbal Therapies

Ernst, E. K. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-137-12-200212170-00024 · Cited by 145 · see citing works

Melatonin

Reiter, R. J., & Tan, D. X. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb02938.x · Cited by 145 · see citing works

Antioxidant activities of six natural phenolics against lipid oxidation induced by Fe2+ or ultraviolet light

Chen, X., & Ahn, D. U. (1998) · Journal of the American Oil Chemists Society · doi:10.1007/s11746-998-0322-2 · Cited by 140 · see citing works

A trace component of ginseng that inhibits Ca2+ channels through a pertussis toxin-sensitive G protein.

Nah, S. Y., Park, H. J., & McCleskey, E. W. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.19.8739 · Cited by 137 · see citing works

Oxidative stress in the aging rat heart is reversed by dietary supplementation with ( R )‐α‐lipoic acid

Suh, J. H., Shigeno, E. T., Morrow, J. D., Cox, J., ROCHA, A. E., Frei, B. B., & Hagen, T. M. (2001) · The FASEB Journal · doi:10.1096/fj.00-0176com · Cited by 133 · see citing works

Melatonin Reduces Oxidant Damage and Promotes Mitochondrial Respiration

Reiter, R. J., TAN, D. X., Manchester, L. C., & El-Sawi, M. R. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb02096.x · Cited by 131 · see citing works

Advances in the Development of Retinoids as Chemopreventive Agents

Lippman, S. M., & Lotan, R. (2000) · Journal of Nutrition · doi:10.1093/jn/130.2.479s · Cited by 131 · see citing works

Position of the American Dietetic Association

Bloch, A. S., & Thomson, C. A. (1995) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(95)00130-1 · Cited by 131 · see citing works

Induction of apoptosis by a novel intestinal metabolite of ginseng saponin via cytochrome c-mediated activation of caspase-3 protease

Lee, S.-J., Ko, W.-G., Kim, J. H., Sung, J.-H., Lee, S.-J., Moon, C.-K., & Lee, B. (2000) · Biochemical Pharmacology · doi:10.1016/s0006-2952(00)00362-2 · Cited by 130 · see citing works

Transcriptional Activation of the Cu,Zn-Superoxide Dismutase Gene through the AP2 Site by Ginsenoside Rb2 Extracted from a Medicinal Plant, Panax ginseng

Kim, Y. H., Park, K. H., & Rhoxy, H. M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.40.24539 · Cited by 125 · see citing works

Alterations in oxidative stress scavenger system in aging rat brain and lymphocytes

Sandhu, S. K., & Kaur, G. (2002) · Biogerontology · doi:10.1023/a:1015643107449 · Cited by 115 · see citing works

Protective effects of carnosine against malondialdehyde-induced toxicity towards cultured rat brain endothelial cells

Hipkiss, A. R., Preston, J. E., Himswoth, D. T. M., Worthington, V., & Abbott, N. J. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00873-2 · Cited by 111 · see citing works

Premature oxidative aging of hepatic mitochondrial DNA in Wilson's disease

Mansouri, A., Gaou, I., Fromenty, B., Berson, A., Lettéron, P., Degott, C., Erlinger, S., & Pessayre, D. (1997) · Gastroenterology · doi:10.1053/gast.1997.v113.pm9247482 · Cited by 105 · see citing works

Ascorbic Acid Status and Subsequent Diastolic and Systolic Blood Pressure

Block, G., Mangels, A. R., Norkus, E. P., Patterson, B. H., Levander, O. A., & Taylor, P. R. (2001) · Hypertension · doi:10.1161/01.hyp.37.2.261 · Cited by 99 · see citing works

Effects of guava intake on serum total and high-density lipoprotein cholesterol levels and on systemic blood pressure

Singh, R. B., Rastogi, S. S., Singh, R., Ghosh, S., & Niaz, M. A. (1992) · The American Journal of Cardiology · doi:10.1016/0002-9149(92)90763-o · Cited by 98 · see citing works

Possible Mechanism by Which Allyl Sulfides Suppress Neoplastic Cell Proliferation

Knowles, L. M., & Milner, J. A. (2001) · Journal of Nutrition · doi:10.1093/jn/131.3.1061s · Cited by 98 · see citing works

An olive oil-rich diet results in higher concentrations of LDL cholesterol and a higher number of LDL subfraction particles than rapeseed oil and sunflower oil diets

Pedersen, A. T., Baumstark, M. W., Marckmann, P., Gylling, H., & Sandström, B. (2000) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32351-8 · Cited by 96 · see citing works

Ebselen Reduces CytochromecRelease From Mitochondria and Subsequent DNA Fragmentation After Transient Focal Cerebral Ischemia in Mice

Namura, S., Nagata, I., Takami, S., Masayasu, H., & Kikuchi, H. (2001) · Stroke · doi:10.1161/01.str.32.8.1906 · Cited by 95 · see citing works

Inhibitory Effects of Persimmon (Diospyros kaki) Extract and Related Polyphenol Compounds on Growth of Human Lymphoid Leukemia Cells

Achiwa, Y., Hibasami, H., Katsuzaki, H., Imai, K., & Komiya, T. (1997) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.61.1099 · Cited by 93 · see citing works

Phyto-oestrogens and breast cancer

Messina, M. J., Barnes, S., & Setchell, K. D. R. (1997) · The Lancet · doi:10.1016/s0140-6736(05)64062-7 · Cited by 91 · see citing works

Antioxidants and Viral Infections: Host Immune Response and Viral Pathogenicity

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Cytotoxicity, genotoxicity and oxidative reactions in cell-culture models: modulatory effects of phytochemicals

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