Cited by 77Suicide and Self-Harm StudiesAutism Spectrum Disorder ResearchChild Nutrition and Feeding Issues

A Comparative Study of Suicidality and Its Association with Emotion Regulation Impairment in Large ASD and US Census-Matched Samples

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Conner, Caitlin M., Golt, Josh, Righi, Giulia, Shaffer, Rebecca, Siegel, Matthew, Mazefsky, Carla A.·2020·Journal of Autism and Developmental Disorders

Abstract

Evidence suggests increased rates of suicidality in autism spectrum disorder (ASD), but the research has rarely used comparison samples and the role of emotion dysregulation has not been considered. We compared the prevalence of parent-reported suicidality ideation and considered the role of emotion dysregulation in 330 psychiatric inpatient youth with ASD, 1169 community youth with ASD surveyed online, and 1000 youth representative of the US census. The prevalence of suicidal ideation was three and five times higher in the community and inpatient ASD samples, respectively, compared to the general US sample. In the ASD groups, greater emotion dysregulation was associated with suicidal ideation. Implications include consideration of emotion regulation as a potential mechanism and treatment target for suicidality in ASD.

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  • Emotional dysregulation is related to the development and maintenance of affective and behavioral problems, and particularly to the development and maintenance of anxiety and depression.

    “La DRE se ha relacionado con el desarrollo y el mantenimiento de problemas afectivos y conductuales (Cai et al., 2018;Conner et al., 2020) y, particularmente, con el desarrollo y mantenimiento de la ansiedad (Cisler y Olatunji, 2012;White et al., 2014) y la depresión (Schäfer et al., 2017).”

    From Ansiedad y trastornos del espectro del autismo: notas para la intervención psicoeducativa (2022) · cites this paper as Conner et al., 2020

    The Discussion > Limitations passage says impaired emotion regulation is associated with psychiatric symptoms and problem behaviors in ASD, supporting the clause for which Conner et al. is cited. It does not establish that dysregulation contributes to the development or maintenance of those problems. The sentence cites other sources, not Conner et al., for the specific claims about anxiety and depression; page numbers are unavailable in our copy. (LLM, conf=0.85)

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  • Emotion dysregulation (ED) has been identified as an important risk factor for self-harm and suicidal behaviors in autistic individuals.

    “Emotion dysregulation (ED), the difficulty in modulating emotions, has been identified as an important risk factor.”

    From Feasibility, Acceptability and Preliminary Efficacy of Dialectical Behavior Therapy for Autistic Adults without Intellectual Disability: A Mixed Methods Study (2022) · cites this paper as Conner et al., 2020

    The Discussion reports that emotion-regulation impairment was significantly associated with parent-reported suicidal ideation and behavior in the ASD groups. The Methods measure of behavior includes deliberate self-harm or attempted suicide. However, the paper describes an association, not an established risk factor, and does not assess self-harm separately from suicide attempts. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • In a sample of autistic children and adolescents, greater ED was associated with an increased likelihood of suicidal ideation and attempts.

    “Indeed, in a sample of autistic children and adolescents, Conner et al. (2020) reported that greater ED was associated with an increased likelihood of suicidal ideation and attempts.”

    From Feasibility, Acceptability and Preliminary Efficacy of Dialectical Behavior Therapy for Autistic Adults without Intellectual Disability: A Mixed Methods Study (2022) · cites this paper as Conner et al., 2020

    The Results report that higher emotion-regulation impairment was associated with parent-reported suicidal ideation and with a combined measure of suicidal behaviors or attempts in the ASD groups. The Discussion > Limitations states that the study did not assess suicide attempts separately, so it cannot establish the claimed association with attempts specifically. Page numbers were not provided in our copy. (LLM, conf=0.90)

    Experimental — accuracy not yet measured
  • There is a growing body of literature suggesting that ED might be a relevant treatment target in autistic individuals, especially those with self-harming behaviors and increased suicidality.

    “There is a growing body of literature suggesting that ED might be a relevant treatment target in autistic individuals (Reyes et al., 2019; Conner et al., 2020), especially those with self-harming behaviors and increased suicidality (Moseley et al., 2019; Conner et al., 2020).”

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Authors
Conner, C. M., Golt, J., Righi, G., Shaffer, R., Siegel, M., & Mazefsky, C. A.
Affiliations
  • University of Pittsburgh (US)
  • Brown University (US)
  • Cincinnati Children's Hospital Medical Center (US)
  • Tufts University (US)
Corresponding author
Mazefsky, Carla A.
Venue
Journal of Autism and Developmental Disorders
Published
2020-01-14
Volume
50
Issue
10
Pages
3545-3560
ISSN
  • 0162-3257 (ISSN-L)
  • 1573-3432
OpenAlex
W3000587089
Cited by
77
References
80
Citations by year
2026: 10 · 2025: 18 · 2024: 18 · 2023: 11 · 2022: 11 · 2021: 7 · 2020: 2
FWCI
3.09
Type
journal article
Language
en
Open access
Locations
  • Journal of Autism and Developmental Disorders (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01 HD079512)
  • Simons Foundation Autism Research Initiative (296318)
  • Nancy Lurie Marks Family Foundation
  • Ritvo-Slifka Award for Innovation in Autism Research
Topics
  • Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
Keywords
autism spectrum disorder, suicidality, suicidal ideation, emotional dysregulation, emotion regulation, youth, psychiatric inpatients, prevalence, U.S. Census
MeSH terms
Autism Spectrum Disorder, Emotional Regulation, Adolescent, Child, Emotions, Female, Humans, Male, Surveys and Questionnaires, Suicide, United States, Prevalence, Censuses, Suicidal Ideation

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