Lifecourse Health Development: Past, Present and Future
Open accessAbstract
During the latter half of the twentieth century, an explosion of research elucidated a growing number of causes of disease and contributors to health. Biopsychosocial models that accounted for the wide range of factors influencing health began to replace outmoded and overly simplified biomedical models of disease causation. More recently, models of lifecourse health development (LCHD) have synthesized research from biological, behavioral and social science disciplines, defined health development as a dynamic process that begins before conception and continues throughout the lifespan, and paved the way for the creation of novel strategies aimed at optimization of individual and population health trajectories. As rapid advances in epigenetics and biological systems research continue to inform and refine LCHD models, our healthcare delivery system has struggled to keep pace, and the gulf between knowledge and practice has widened. This paper attempts to chart the evolution of the LCHD framework, and illustrate its potential to transform how the MCH system addresses social, psychological, biological, and genetic influences on health, eliminates health disparities, reduces chronic illness, and contains healthcare costs. The LCHD approach can serve to highlight the foundational importance of MCH, moving it from the margins of national debate to the forefront of healthcare reform efforts. The paper concludes with suggestions for innovations that could accelerate the translation of health development principles into MCH practice.
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Individual traits that allow adaptive or maladaptive outcomes depend upon the unique neurological capacity of each individual, which is built upon experiences in the life course, particularly those early in life.
“The individual traits that allow these adaptive or maladaptive outcomes depend upon the unique neurological capacity of each individual, which is built upon experiences in the life course, particularly those early in life.”
From Neurobiological and Systemic Effects of Chronic Stress (2017) · cites this paper as [68]
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- Authors
- Halfon, N., Larson, K., Lu, M., Tullis, E., & Russ, S.
- Affiliations
- University of California, Los Angeles (US)
- American Academy of Pediatrics (US)
- United States Department of Health and Human Services (US)
- Corresponding author
- Halfon, Neal
- Venue
- Maternal and Child Health Journal
- Published
- 2013-08-22
- Volume
- 18
- Issue
- 2
- Pages
- 344-365
- ISSN
- 1092-7875 (ISSN-L)
- 1573-6628
- PMC
- PMC3890560
- OpenAlex
- W1988065397
- Cited by
- 567
- References
- 160
- Citations by year
- 2026: 43 · 2025: 38 · 2024: 46 · 2023: 57 · 2022: 65 · 2021: 34 · 2020: 38 · 2019: 55 · 2018: 44 · 2017: 49 · 2016: 45 · 2015: 38 · 2014: 12 · 2013: 2
- FWCI
- 58.26
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Maternal and Child Health Journal (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Health Resources and Services Administration
- Maternal and Child Health Bureau
- Topics
- Health Sciences › Health Professions › General Health Professions › Child and Adolescent Health
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Keywords
- biopsychosocial model, etiology, epigenetics, maternal and child health, health disparities, chronic disease prevention, health care costs, health care reform, knowledge-practice gap, health trajectories, clinical translation
- MeSH terms
- Critical Period, Psychological, Health Policy, Health Status, Humans, Human Development, Maternal-Child Health Centers, Models, Biological, Public Health, Biomedical Research, Fetal Development, Systems Biology, Epigenomics, Social Determinants of Health
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