Mechanisms of stress in the brain

Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults

Felitti, V. J., Anda, R. F., Nordenberg, D., Williamson, D. F., Spitz, A. M., Edwards, V., Koss, M. P., & Marks, J. S. (1998) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(98)00017-8 · Cited by 18,943 · see citing works

Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

Shrestha, S., & Offer, S. M. (2016) · Medical Epigenetics · doi:10.1159/000444713 · Cited by 8,949 · see citing works

Child abuse: Adolescent records vs. adult recall

Femina, D. D., Yeager, C. A., & Lewis, D. O. (1990) · Child Abuse & Neglect · doi:10.1016/0145-2134(90)90033-p · Cited by 8,820 · see citing works

Protective and Damaging Effects of Stress Mediators

McEwen, B. S. (1998) · New England Journal of Medicine · doi:10.1056/nejm199801153380307 · Cited by 6,733 · see citing works

Physiology and neurobiology of stress and adaptation: central role of the brain

McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 4,981 · see citing works

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

McGowan, P. O., Sasaki, A., D'Alessio, A. C., Dymov, S., Labonté, B., Szyf, M., Turecki, G., & Meaney, M. J. (2009) · Nature Neuroscience · doi:10.1038/nn.2270 · Cited by 3,531 · see citing works

The concept of allostasis in biology and biomedicine

McEwen, B. S., & Wingfield, J. C. (2003) · Hormones and Behavior · doi:10.1016/s0018-506x(02)00024-7 · Cited by 3,302 · see citing works

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

Khalil, A. M., Guttman, M., Huarte, M., Garber, M., Raj, A., Rivea Morales, D., Thomas, K., Presser, A., Bernstein, B. E., van Oudenaarden, A., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904715106 · Cited by 2,872 · see citing works

The Significance of Responses of the Genome to Challenge

McClintock, B. (1984) · Science · doi:10.1126/science.15739260 · Cited by 2,638 · see citing works

Neuroscience, Molecular Biology, and the Childhood Roots of Health Disparities: Building a New Framework for Health Promotion and Disease Prevention

Shonkoff, J. P., Boyce, W. T., & McEwen, B. S. (2009) · JAMA · doi:10.1001/jama.2009.754 · Cited by 2,326 · see citing works

The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis

Sapolsky, R. M., Krey, L. C., & McEwen, B. S. (1986) · Science of Aging Knowledge Environment · doi:10.1126/sageke.2002.38.cp21 · Cited by 2,287 · see citing works

STRESS AND HIPPOCAMPAL PLASTICITY

McEwen, B. S. (1999) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.22.1.105 · Cited by 2,087 · see citing works

Nongenomic Transmission Across Generations of Maternal Behavior and Stress Responses in the Rat

Francis, D., Diorio, J., Liu, D., & Meaney, M. J. (1999) · Science · doi:10.1126/science.286.5442.1155 · Cited by 1,965 · see citing works

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

Tsankova, N. M., Berton, O., Renthal, W., Kumar, A., Neve, R. L., & Nestler, E. J. (2006) · Nature Neuroscience · doi:10.1038/nn1659 · Cited by 1,780 · see citing works

Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons

Vyas, A., Mitra, R., Shankaranarayana Rao, B. S., & Chattarji, S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06810.2002 · Cited by 1,662 · see citing works

Neurogenesis in the Dentate Gyrus of the Adult Tree Shrew Is Regulated by Psychosocial Stress and NMDA Receptor Activation

Gould, E., McEwen, B. S., Tanapat, P., Galea, L. A. M., & Fuchs, E. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-07-02492.1997 · Cited by 1,496 · see citing works

Epigenetic regulation in psychiatric disorders

Tsankova, N., Renthal, W., Kumar, A., & Nestler, E. J. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2132 · Cited by 1,400 · see citing works

Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress

Gould, E., Tanapat, P., McEwen, B. S., Flügge, G., & Fuchs, E. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.6.3168 · Cited by 1,395 · see citing works

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

Popoli, M., Yan, Z., McEwen, B. S., & Sanacora, G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3138 · Cited by 1,393 · see citing works

Protective and damaging effects of stress mediators: central role of the brain

McEwen, B. S. (2006) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2006.8.4/bmcewen · Cited by 1,220 · see citing works

Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons

Watanabe, Y., Gould, E., & McEwen, B. S. (1992) · Brain Research · doi:10.1016/0006-8993(92)91597-8 · Cited by 1,212 · see citing works

CHROMOSOME ORGANIZATION AND GENIC EXPRESSIONPreprint

McClintock, B. (1951) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1951.016.01.004 · Cited by 1,211 · see citing works

Neurobiology of resilience

Russo, S. J., Murrough, J. W., Han, M.-H., Charney, D. S., & Nestler, E. J. (2012) · Nature Neuroscience · doi:10.1038/nn.3234 · Cited by 1,206 · see citing works

Brain on stress: how the social environment gets under the skin

McEwen, B. S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121254109 · Cited by 1,200 · see citing works

Stress- and Allostasis-Induced Brain Plasticity

McEwen, B. S., & Gianaros, P. J. (2011) · Annual Review of Medicine · doi:10.1146/annurev-med-052209-100430 · Cited by 1,171 · see citing works

The Brain on Stress: Vulnerability and Plasticity of the Prefrontal Cortex over the Life Course

McEwen, B. S., & Morrison, J. H. (2013) · Neuron · doi:10.1016/j.neuron.2013.06.028 · Cited by 1,079 · see citing works

Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus

Cameron, H. A., & Gould, E. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90224-0 · Cited by 999 · see citing works

Stress-Induced Alterations in Prefrontal Cortical Dendritic Morphology Predict Selective Impairments in Perceptual Attentional Set-Shifting

Liston, C., Miller, M. M., Goldwater, D. S., Radley, J. J., Rocher, A. B., Hof, P. R., Morrison, J. H., & McEwen, B. S. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1184-06.2006 · Cited by 968 · see citing works

Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome

Meaney, M. J., & Szyf, M. (2005) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2005.7.2/mmeaney · Cited by 958 · see citing works

The many faces of tau

Morris, M., Maeda, S., Vossel, K., & Mucke, L. (2011) · Neuron · doi:10.1016/j.neuron.2011.04.009 · Cited by 899 · see citing works

The role of BDNF and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity

Castrén, E., & Rantamäki, T. (2010) · Developmental Neurobiology · doi:10.1002/dneu.20758 · Cited by 864 · see citing works

Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Involvement of glucocorticoid secretion and excitatory amino acid receptors

Magarin˜os, A. M., & McEwen, B. S. (1995) · Neuroscience · doi:10.1016/0306-4522(95)00259-l · Cited by 863 · see citing works

Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone

Karst, H., Berger, S., Turiault, M., Tronche, F., Schütz, G., & Joëls, M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507572102 · Cited by 774 · see citing works

Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex

Radley, J. J., Sisti, H. M., Hao, J., Rocher, A. B., McCall, T., Hof, P. R., McEwen, B. S., & Morrison, J. H. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.01.006 · Cited by 769 · see citing works

Selective Retention of Corticosterone by Limbic Structures in Rat Brain

McEwen, B. S., Weiss, J. M., & Schwartz, L. S. (1968) · Nature · doi:10.1038/220911a0 · Cited by 713 · see citing works

Stress duration modulates the spatiotemporal patterns of spine formation in the basolateral amygdala

Mitra, R., Jadhav, S., McEwen, B. S., Vyas, A., & Chattarji, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504011102 · Cited by 663 · see citing works

Repeated restraint stress suppresses neurogenesis and induces biphasic PSA‐NCAM expression in the adult rat dentate gyrus

Pham, K., Nacher, J., Hof, P. R., & McEwen, B. S. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02513.x · Cited by 657 · see citing works

Non-coding RNAs as regulators of embryogenesis

Pauli, A., Rinn, J. L., & Schier, A. F. (2011) · Nature Reviews Genetics · doi:10.1038/nrg2904 · Cited by 623 · see citing works

Relating Hippocampal Circuitry to Function

Lisman, J. E. (1999) · Neuron · doi:10.1016/s0896-6273(00)81085-5 · Cited by 607 · see citing works

Removing brakes on adult brain plasticity: From molecular to behavioral interventions

Bavelier, D., Levi, D. M., Li, R. W., Dan, Y., & Hensch, T. K. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4812-10.2010 · Cited by 589 · see citing works

Polysialic acid in the plasticity of the developing and adult vertebrate nervous system

Rutishauser, U. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2285 · Cited by 584 · see citing works

Socio‐economic differentials in peripheral biology: Cumulative allostatic load

Seeman, T., Epel, E., Gruenewald, T., Karlamangla, A., & McEwen, B. S. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05341.x · Cited by 579 · see citing works

Lifecourse Health Development: Past, Present and Future

Halfon, N., Larson, K., Lu, M., Tullis, E., & Russ, S. (2014) · Maternal and Child Health Journal · doi:10.1007/s10995-013-1346-2 · Cited by 567 · see citing works

W. H. Fox Talbot and the history of photography

Gernsheim, H. (1977) · Endeavour · doi:10.1016/0160-9327(77)90005-9 · Cited by 565 · see citing works

Disruption of circadian clocks has ramifications for metabolism, brain, and behavior

Karatsoreos, I. N., Bhagat, S., Bloss, E. B., Morrison, J. H., & McEwen, B. S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1018375108 · Cited by 547 · see citing works

Transposable elements reveal a stem cell-specific class of long noncoding RNAs

Kelley, D., & Rinn, J. (2012) · Genome Biology · doi:10.1186/gb-2012-13-11-r107 · Cited by 531 · see citing works

Dynamic regulation of mitochondrial function by glucocorticoids

Du, J., Wang, Y., Hunter, R. G., Wei, Y., Blumenthal, R., Falke, C., Khairova, R. A., Zhou, R., Yuan, P., Machado‐Vieira, R., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812671106 · Cited by 494 · see citing works

Psychobiological allostasis: resistance, resilience and vulnerability

Karatsoreos, I. N., & McEwen, B. S. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.10.005 · Cited by 458 · see citing works

Overview on the structure, composition, function, development, and plasticity of hippocampal dendritic spines

Sorra, K. E., & Harris, K. M. (2000) · Hippocampus · doi:10.1002/1098-1063(2000)10:5 · Cited by 456 · see citing works

Acute corticosterone treatment is sufficient to induce anxiety and amygdaloid dendritic hypertrophy

Mitra, R., & Sapolsky, R. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705615105 · Cited by 409 · see citing works

Corticosteroid effects in the brain: U-shape it

Joëls, M. (2006) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2006.03.007 · Cited by 408 · see citing works

Gene Coexpression Networks in Human Brain Identify Epigenetic Modifications in Alcohol Dependence

Ponomarev, I., Wang, S., Zhang, L., Harris, R. A., & Mayfield, R. D. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.3136-11.2012 · Cited by 377 · see citing works

Stress, cognitive impairment and cell adhesion molecules

Sandi, C. (2004) · Nature reviews. Neuroscience · doi:10.1038/nrn1555 · Cited by 374 · see citing works

Downregulation of Endocannabinoid Signaling in the Hippocampus Following Chronic Unpredictable Stress

Hill, M. N., Patel, S., Carrier, E. J., Rademacher, D. J., Ormerod, B. K., Hillard, C. J., & Gorzalka, B. B. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300601 · Cited by 363 · see citing works

Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance.

Liston, C., Cichon, J. M., Jeanneteau, F., Jia, Z., Chao, M. V., & Gan, W.-B. (2013) · Nature Neuroscience · doi:10.1038/nn.3387 · Cited by 358 · see citing works

Recruitment of Prefrontal Cortical Endocannabinoid Signaling by Glucocorticoids Contributes to Termination of the Stress Response

Hill, M. N., McLaughlin, R. J., Pan, B., Fitzgerald, M. L., Roberts, C. J., Lee, T. T. Y., Karatsoreos, I. N., Mackie, K., Viau, V., Pickel, V. M., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0496-11.2011 · Cited by 357 · see citing works

Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals

Arendt, T., Stieler, J., Strijkstra, A. M., Hut, R. A., Rüdiger, J., Van der Zee, E. A., Harkany, T., Holzer, M., & Härtig, W. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-18-06972.2003 · Cited by 357 · see citing works

Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo

Liston, C., & Gan, W.-B. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1110444108 · Cited by 352 · see citing works

Endogenous cannabinoid signaling is essential for stress adaptation

Hill, M. N., McLaughlin, R. J., Bingham, B., Shrestha, L., Lee, T. T. Y., Gray, J. M., Hillard, C. J., Gorzalka, B. B., & Viau, V. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914661107 · Cited by 349 · see citing works

Environmental influence in the brain, human welfare and mental health

Tost, H., Champagne, F. A., & Meyer‐Lindenberg, A. (2015) · Nature Neuroscience · doi:10.1038/nn.4108 · Cited by 349 · see citing works

Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat

Szyf, M., Weaver, I. C. G., Champagne, F. A., Diorio, J., & Meaney, M. J. (2005) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2005.10.002 · Cited by 348 · see citing works

Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress

Bortolato, M., Mangieri, R. A., Fu, J., Kim, J. H., Arguello, O., Duranti, A., Tontini, A., Mor, M., Tarzia, G., & Piomelli, D. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.12.001 · Cited by 347 · see citing works

Rapid Communication: Adrenalectomy Attenuates Stress‐Induced Elevations in Extracellular Glutamate Concentrations in the Hippocampus

Lowy, M. T., Gault, L. M., & Yamamoto, B. K. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb09839.x · Cited by 343 · see citing works

Stress, sex, and neural adaptation to a changing environment: mechanisms of neuronal remodeling

McEwen, B. S. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05568.x · Cited by 335 · see citing works

Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery

Goldwater, D. S., Pavlides, C., Hunter, R. G., Bloss, E. B., Hof, P. R., McEwen, B. S., & Morrison, J. H. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.08.053 · Cited by 333 · see citing works

Transgenic brain-derived neurotrophic factor expression causes both anxiogenic and antidepressant effects

Govindarajan, A., Rao, B. S. S., Nair, D., Trinh, M. A., Mawjee, N., Tonegawa, S., & Chattarji, S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605180103 · Cited by 332 · see citing works

The RIDL hypothesis: transposable elements as functional domains of long noncoding RNAs

Johnson, R., & Guigó, R. (2014) · RNA · doi:10.1261/rna.044560.114 · Cited by 308 · see citing works

Recognizing resilience: Learning from the effects of stress on the brain

McEwen, B. S., Gray, J. D., & Nasca, C. (2015) · Neurobiology of Stress · doi:10.1016/j.ynstr.2014.09.001 · Cited by 292 · see citing works

High dose hydrocortisone immediately after trauma may alter the trajectory of PTSD: Interplay between clinical and animal studies

Zohar, J., Yahalom, H., Kozlovsky, N., Cwikel-Hamzany, S., Matar, M. A., Kaplan, Z., Yehuda, R., & Cohen, H. (2011) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2011.06.001 · Cited by 292 · see citing works

Regulation of hippocampal H3 histone methylation by acute and chronic stress

Hunter, R. G., McCarthy, K. J., Milne, T. A., Pfaff, D. W., & McEwen, B. S. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911143106 · Cited by 290 · see citing works

Mobile DNA elements in the generation of diversity and complexity in the brain

Erwin, J. A., Marchetto, M. C., & Gage, F. H. (2014) · Nature reviews. Neuroscience · doi:10.1038/nrn3730 · Cited by 264 · see citing works

L -acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors

Nasca, C., Xenos, D., Barone, Y., Caruso, A., Scaccianoce, S., Matrisciano, F., Battaglia, G., Mathé, A. A., Pittaluga, A., Lionetto, L., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1216100110 · Cited by 263 · see citing works

Glucocorticoid signaling synchronizes the liver circadian transcriptome

Reddy, A. B., Maywood, E. S., Karp, N. A., King, V. M., Inoue, Y., Gonzalez, F. J., Lilley, K. S., Kyriacou, C. P., & Hastings, M. H. (2007) · Hepatology · doi:10.1002/hep.21571 · Cited by 261 · see citing works

The central and basolateral nuclei of the amygdala exhibit opposite diurnal rhythms of expression of the clock protein Period2

Lamont, E. W., Robinson, B., Stewart, J., & Amir, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500901102 · Cited by 256 · see citing works

Stress Leads to Contrasting Effects on the Levels of Brain Derived Neurotrophic Factor in the Hippocampus and Amygdala

Lakshminarasimhan, H., & Chattarji, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030481 · Cited by 253 · see citing works

Glucocorticoid receptor overexpression in forebrain: A mouse model of increased emotional lability

Wei, Q., Lu, X., Liu, L., Schafer, G. L., Shieh, K.-R., Burke, S., Robinson, T. E., Watson, S. J., Seasholtz, A. F., & Akil, H. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402208101 · Cited by 249 · see citing works

Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety

Gray, J. M., Vecchiarelli, H. A., Morena, M., Lee, T. T. Y., Hermanson, D. J., Kim, A. B., McLaughlin, R. J., Hassan, K. I., Kühne, C., Wotjak, C. T., et al. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.2737-14.2015 · Cited by 246 · see citing works

Dynamic plasticity: The role of glucocorticoids, brain-derived neurotrophic factor and other trophic factors

Gray, J. D., Milner, T. A., & McEwen, B. S. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.08.034 · Cited by 242 · see citing works

Hippocampal gene expression changes underlying stress sensitization and recovery

Gray, J. D., Rubin, T. G., Hunter, R. G., & McEwen, B. S. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.175 · Cited by 242 · see citing works

Repeated changes of dendritic morphology in the hippocampus of ground squirrels in the course of hibernation

Popov, V. I., Bocharova, L. S., & Bragin, A. G. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90336-z · Cited by 241 · see citing works

The significance of glucocorticoid pulsatility

Lightman, S. L., Wiles, C. C., Atkinson, H. C., Henley, D. E., Russell, G. M., Leendertz, J. A., McKenna, M. A., Spiga, F., Wood, S. A., & Conway-Campbell, B. L. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.11.073 · Cited by 241 · see citing works

Oxytocin stimulates adult neurogenesis even under conditions of stress and elevated glucocorticoids

Leuner, B., Caponiti, J., & Gould, E. (2011) · Hippocampus · doi:10.1002/hipo.20947 · Cited by 237 · see citing works

Involvement of the endocannabinoid system in the neurobehavioural effects of stress and glucocorticoids

Hill, M. N., & McEwen, B. S. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.11.001 · Cited by 235 · see citing works

Amygdala FAAH and anandamide: mediating protection and recovery from stress

Gunduz-Cinar, O., Hill, M. N., McEwen, B. S., & Holmes, A. (2013) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2013.08.008 · Cited by 229 · see citing works

Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors

Heller, E. A., Cates, H. M., Peña, C. J., Sun, H., Shao, N., Feng, J., Golden, S. A., Herman, J. P., Walsh, J. J., Mazei-Robison, M., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3871 · Cited by 227 · see citing works

Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus

Pawlak, R., Rao, B. S. S., Melchor, J. P., Chattarji, S., McEwen, B., & Strickland, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509232102 · Cited by 223 · see citing works

Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure

Hill, M. N., Kumar, S. A., Filipski, S. B., Iverson, M., Stuhr, K. L., Keith, J. M., Cravatt, B. F., Hillard, C. J., Chattarji, S., & McEwen, B. S. (2013) · Molecular Psychiatry · doi:10.1038/mp.2012.90 · Cited by 222 · see citing works

Mechanisms Generating Diversity in Glucocorticoid Receptor Signaling

Revollo, J. R., & Cidlowski, J. A. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04986.x · Cited by 220 · see citing works

Early Stress Evokes Age-Dependent Biphasic Changes in Hippocampal Neurogenesis, Bdnf Expression, and Cognition

Suri, D., Veenit, V., Sarkar, A., Thiagarajan, D., Kumar, A., Nestler, E. J., Galande, S., & Vaidya, V. A. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.10.023 · Cited by 208 · see citing works

Glucocorticoid endangerment of hippocampal neurons is NMDA-receptor dependent

Armanini, M. P., Hutchins, C., Stein-Behrens, B., & Sapolsky, R. M. (1990) · Brain Research · doi:10.1016/0006-8993(90)91734-x · Cited by 205 · see citing works

Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility

Nasca, C., Bigio, B., Zelli, D., Nicoletti, F., & McEwen, B. S. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.96 · Cited by 194 · see citing works

Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation

Mucha, M. W., Skrzypiec, A. E., Schiavon, E., Attwood, B. K., Kucerova, E., & Pawlak, R. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1107936108 · Cited by 189 · see citing works

Cell Surface Expression of Polysialic Acid on NCAM Is a Prerequisite for Activity-Dependent Morphological Neuronal and Glial Plasticity

Theodosis, D. T., Bonhomme, R., Vitiello, S., Rougon, G. N., & Poulain, D. A. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-23-10228.1999 · Cited by 183 · see citing works

Acute stress and hippocampal histone H3 lysine 9 trimethylation, a retrotransposon silencing response

Hunter, R. G., Murakami, G., Dewell, S. B., Seligsohn, M., Baker, M. E. R., Datson, N. A., McEwen, B. S., & Pfaff, D. W. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1215810109 · Cited by 175 · see citing works

The Role of Transposable Elements in Health and Diseases of the Central Nervous System

Reilly, M. T., Faulkner, G. J., Dubnau, J., Ponomarev, I., & Gage, F. H. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3369-13.2013 · Cited by 175 · see citing works

Sexual Experience Promotes Adult Neurogenesis in the Hippocampus Despite an Initial Elevation in Stress Hormones

Leuner, B., Glasper, E. R., & Gould, E. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011597 · Cited by 169 · see citing works

Gene expression profiling of major depression and suicide in the prefrontal cortex of postmortem brains

Tochigi, M., Iwamoto, K., Bundo, M., Sasaki, T., Kato, N., & Kato, T. (2007) · Neuroscience Research · doi:10.1016/j.neures.2007.10.010 · Cited by 156 · see citing works

Antidepressant actions of ketamine: from molecular mechanisms to clinical practice

Monteggia, L. M., & Zarate, C. (2015) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.12.004 · Cited by 149 · see citing works

Making memories of stressful events: a journey along epigenetic, gene transcription, and signaling pathways

Reul, J. M. H. M. (2014) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2014.00005 · Cited by 147 · see citing works

Rapid and reversible changes in intrahippocampal connectivity during the course of hibernation in European hamsters

Magariños, A. M., McEwen, B. S., Saboureau, M., & Pévet, P. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608785103 · Cited by 145 · see citing works

Stress-induced spine loss in the medial amygdala is mediated by tissue-plasminogen activator

Bennur, S., Rao, B. S. S., Pawlak, R., Strickland, S., McEwen, B. S., & Chattarji, S. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.075 · Cited by 145 · see citing works

Acute and chronic restraint stress alter the incidence of social conflict in male rats

Wood, G. E., Young, L. T., Reagan, L. P., & McEwen, B. S. (2003) · Hormones and Behavior · doi:10.1016/s0018-506x(02)00026-0 · Cited by 141 · see citing works

Therapeutic Potential of Inhibitors of Endocannabinoid Degradation for the Treatment of Stress-Related Hyperalgesia in an Animal Model of Chronic Pain

Lomazzo, E., Bîndilă, L., Remmers, F., Lerner, R., Schwitter, C., Hoheisel, U., & Lutz, B. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.198 · Cited by 141 · see citing works

Stress and Anxiety Across the Lifespan: Structural Plasticity and Epigenetic Regulation

Hunter, R. G., & McEwen, B. S. (2013) · Epigenomics · doi:10.2217/epi.13.8 · Cited by 141 · see citing works

Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations

van der Kooij, M. A., Fantin, M., Rejmak, E., Grosse, J., Zanoletti, O., Fournier, C., Ganguly, K., Kalita, K., Kaczmarek, L., & Sandi, C. (2014) · Nature Communications · doi:10.1038/ncomms5995 · Cited by 140 · see citing works

Glucocorticoid signaling and stress-related limbic susceptibility pathway: About receptors, transcription machinery and microRNA

de Kloet, E. R., Fitzsimons, C. P., Datson, N. A., Meijer, O. C., & Vreugdenhil, E. (2009) · Brain Research · doi:10.1016/j.brainres.2009.03.039 · Cited by 139 · see citing works

NMDA Receptor Blockade Alters Stress-Induced Dendritic Remodeling in Medial Prefrontal Cortex

Martin, K. P., & Wellman, C. L. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr021 · Cited by 138 · see citing works

RNA–protein interactions in human health and disease

Khalil, A. M., & Rinn, J. L. (2011) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2011.02.016 · Cited by 138 · see citing works

Stress and corticosterone increase the readily releasable pool of glutamate vesicles in synaptic terminals of prefrontal and frontal cortex

Treccani, G., Musazzi, L., Perego, C., Milanese, M., Nava, N., Bonifacino, T., Lamanna, J., Malgaroli, A., Drago, F., Racagni, G., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.5 · Cited by 133 · see citing works

Stress and the dynamic genome: Steroids, epigenetics, and the transposome

Hunter, R. G., Gagnidze, K., McEwen, B. S., & Pfaff, D. W. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1411260111 · Cited by 133 · see citing works

DNA Methylation in Repetitive Elements and Post-Traumatic Stress Disorder: A Case–Control Study of US Military Service Members

Rusiecki, J. A., Chen, L., Srikantan, V., Zhang, L., Yan, L., Polin, M., & Baccarelli, A. (2012) · Epigenomics · doi:10.2217/epi.11.116 · Cited by 132 · see citing works

Glucocorticoids Protect Against the Delayed Behavioral and Cellular Effects of Acute Stress on the Amygdala

Rao, R. P., Anilkumar, S., McEwen, B. S., & Chattarji, S. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.04.008 · Cited by 131 · see citing works

Can Posttraumatic Stress Disorder Be Prevented with Glucocorticoids?

SCHELLING, G., ROOZENDAAL, B., & de QUERVAIN, D. J. ‐. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1314.013 · Cited by 130 · see citing works

Alterations in Corticolimbic Dendritic Morphology and Emotional Behavior in Cannabinoid CB1 Receptor-Deficient Mice Parallel the Effects of Chronic Stress

Hill, M. N., Hillard, C. J., & McEwen, B. S. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq280 · Cited by 127 · see citing works

Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes

Daskalakis, N. P., Cohen, H., Cai, G., Buxbaum, J. D., & Yehuda, R. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1401660111 · Cited by 124 · see citing works

Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation

Zoppi, S., Perez‐Nievas, B. G., Madrigal, J. L. M., Manzanares, J., Leza, J. C., & García‐Bueno, B. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.214 · Cited by 116 · see citing works

Tissue plasminogen activator promotes the effects of corticotropin releasing factor on the amygdala and anxiety-like behavior

Matys, T., Pawlak, R., Matys, E., Pavlides, C., McEwen, B. S., & Strickland, S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407355101 · Cited by 111 · see citing works

Neuroepigenetics of stress

Griffiths, B. B., & Hunter, R. G. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.06.041 · Cited by 111 · see citing works

Amygdala Transcriptome and Cellular Mechanisms Underlying Stress-Enhanced Fear Learning in a Rat Model of Posttraumatic Stress Disorder

Ponomarev, I., Rau, V., Eger, E. I., Harris, R. A., & Fanselow, M. S. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.10 · Cited by 109 · see citing works

Previous History of Chronic Stress Changes the Transcriptional Response to Glucocorticoid Challenge in the Dentate Gyrus Region of the Male Rat Hippocampus

Datson, N. A., van den Oever, J. M. E., Korobko, O. B., Magariños, A. M., de Kloet, E. R., & McEwen, B. S. (2013) · Endocrinology · doi:10.1210/en.2012-2233 · Cited by 105 · see citing works

Glucocorticoid receptors modulate mitochondrial function

Du, J., McEwen, B. S., & Manji, H. K. (2009) · Communicative & Integrative Biology · doi:10.4161/cib.2.4.8554 · Cited by 102 · see citing works

Cellular and molecular mechanisms of hippocampal activation by acute stress are age-dependent

Chen, Y., Fenoglio, K. A., Dubé, C. M., Grigoriadis, D. E., & Baram, T. Z. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001863 · Cited by 98 · see citing works

Epigenetic mechanisms in stress-related memory formation

Reul, J. M. H. M., & Chandramohan, Y. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.03.016 · Cited by 92 · see citing works

Cortical organization in shrews: Evidence from five species

Catania, K. C., Lyon, D. C., Mock, O. B., & Kaas, J. H. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990719)410:1 · Cited by 90 · see citing works

Impaired Hippocampal Neuroligin-2 Function by Chronic Stress or Synthetic Peptide Treatment is Linked to Social Deficits and Increased Aggression

van der Kooij, M. A., Fantin, M., Kraev, I., Korshunova, I., Grosse, J., Zanoletti, O., Guirado, R., García-Mompó, C., Nácher, J., Stewart, M. G., et al. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.315 · Cited by 89 · see citing works

Preservation of striatal cannabinoid CB1 receptor function correlates with the antianxiety effects of fatty acid amide hydrolase inhibition

Rossi, S., De Chiara, V., Musella, A., Sacchetti, L., Cantarella, C., Castelli, M., Cavasinni, F., Motta, C., Studer, V., Bernardi, G., et al. (2010) · Molecular Pharmacology · doi:10.1124/mol.110.064196 · Cited by 82 · see citing works

Constant Corticosterone Replacement Normalizes Basal Adrenocorticotropin (ACTH) but Permits Sustained ACTH Hypersecretion After Stress in Adrenalectomized Rats*

Akana, S. F., Jacobson, L., Cascio, C. S., Shinsako, J., & Dallman, M. F. (1988) · Endocrinology · doi:10.1210/endo-122-4-1337 · Cited by 78 · see citing works

Environmental disruption of the circadian clock leads to altered sleep and immune responses in mouse

Phillips, D. J., Savenkova, M. I., & Karatsoreos, I. N. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2014.12.008 · Cited by 65 · see citing works

Chronic, noninvasive glucocorticoid administration suppresses limbic endocannabinoid signaling in mice

Bowles, N. P., Hill, M. N., Bhagat, S. M., Karatsoreos, I. N., Hillard, C. J., & McEwen, B. S. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.08.048 · Cited by 63 · see citing works

Environmental stress and transposon transcription in the mammalian brain

Hunter, R. G., McEwen, B. S., & Pfaff, D. W. (2013) · Mobile Genetic Elements · doi:10.4161/mge.24555 · Cited by 58 · see citing works

Role for NUP62 depletion and PYK2 redistribution in dendritic retraction resulting from chronic stress

Kinoshita, Y., Hunter, R. G., Gray, J. D., Mesias, R., McEwen, B. S., Benson, D. L., & Kohtz, D. S. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1418896111 · Cited by 51 · see citing works

Experience and the ever‐changing brain: What the transcriptome can reveal

Rubin, T. G., Gray, J. D., & McEwen, B. S. (2014) · BioEssays · doi:10.1002/bies.201400095 · Cited by 47 · see citing works

Stress-Induced Lipocalin-2 Controls Dendritic Spine Formation and Neuronal Activity in the Amygdala

Skrzypiec, A. E., Shah, R. S., Schiavon, E., Baker, E., Skene, N., Pawlak, R., & Mucha, M. W. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061046 · Cited by 47 · see citing works

Depletion of polysialic acid from neural cell adhesion molecule (PSA-NCAM) increases CA3 dendritic arborization and increases vulnerability to excitotoxicity

McCall, T., Weil, Z. M., Nacher, J., Bloss, E. B., El Maarouf, A., Rutishauser, U., & McEwen, B. S. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2012.11.028 · Cited by 34 · see citing works

Epigenetic regulation of Dnmt3a and Arc gene expression after electroconvulsive stimulation in the rat

Dyrvig, M., Gøtzsche, C. R., Woldbye, D. P. D., et al. (2015) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2015.06.011 · Cited by 21 · see citing works

Forebrain glucocorticoid receptor gene deletion attenuates behavioral changes and antidepressant responsiveness during chronic stress

Jacobson, L. (2014) · Brain Research · doi:10.1016/j.brainres.2014.07.054 · Cited by 21 · see citing works

Transcriptome profiling analysis reveals region‐distinctive changes of gene expression in the CNS in response to different moderate restraint stress

Wang, K., Xiang, X., He, F., Lin, L., Zhang, R., Ping, X., Han, J., Guo, N., Zhang, Q., Cui, C., et al. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06679.x · Cited by 18 · see citing works

Timing is everything: a collection on how clocks affect resilience in biological systems

Karatsoreos, I. N., & McEwen, B. S. (2014) · F1000Research · doi:10.12688/f1000research.5756.1 · Cited by 17 · see citing works

Morphological and behavioral evidence for impaired prefrontal cortical function in female CB1 receptor deficient mice

Lee, T. T.-Y., Filipski, S. B., Hill, M. N., & McEwen, B. S. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.064 · Cited by 16 · see citing works

Episodic memory, semantic memory, and amnesia

Squire, L. R., & Zola, S. M. (1998) · Hippocampus · doi:10.1002/(sici)1098-1063(1998)8:3

The theory of constructed emotion: an active inference account of interoception and categorization

Barrett, L. F. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw154 · Cited by 1,426 · see citing works

Allostatic load and its impact on health: A systematic review

Guidi, J., Lucente, M., Sonino, N., & Fava, G. A. (2021) · Psychotherapy and Psychosomatics · doi:10.1159/000510696 · Cited by 1,266 · see citing works

Subcortical brain alterations in major depressive disorder: Findings from the ENIGMA Major Depressive Disorder working group

for the ENIGMA-Major Depressive Disorder Working Group, Schmaal, L., Veltman, D. J., van Erp, T. G. M., Sämann, P. G., Frodl, T., Jahanshad, N., Loehrer, E., Tiemeier, H., Hofman, A., et al. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.69 · Cited by 1,172 · see citing works

Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy

Van den Bergh, B. R. H., van den Heuvel, M. I., Lahti, M., Braeken, M., de Rooij, S. R., Entringer, S., Hoyer, D., Roseboom, T., Räikkönen, K., King, S., et al. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.07.003 · Cited by 1,181 · see citing works

Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments

Duman, R. S., Sanacora, G., & Krystal, J. H. (2019) · Neuron · doi:10.1016/j.neuron.2019.03.013 · Cited by 1,026 · see citing works

The theory of constructed emotion: an active inference account of interoception and categorization

Barrett, L. F. (2017) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsx060 · Cited by 950 · see citing works

The Semantics of Microglia Activation: Neuroinflammation, Homeostasis, and Stress

Woodburn, S. C., Bollinger, J. L., & Wohleb, E. S. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02309-6 · Cited by 783 · see citing works

Social determinants of health and survival in humans and other animals

Snyder-Mackler, N., Burger, J. R., Gaydosh, L., Belsky, D. W., Noppert, G. A., Campos, F. A., Bartolomucci, A., Yang, Y. C., Aiello, A. E., O’Rand, A., et al. (2020) · Science · doi:10.1126/science.aax9553 · Cited by 679 · see citing works

Uncertainty and stress: Why it causes diseases and how it is mastered by the brain

Peters, A., McEwen, B. S., & Friston, K. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2017.05.004 · Cited by 652 · see citing works

Delirium pathophysiology: An updated hypothesis of the etiology of acute brain failure

Maldonado, J. R. (2018) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4823 · Cited by 617 · see citing works

How do antidepressants work? New perspectives for refining future treatment approaches

Harmer, C. J., Duman, R. S., & Cowen, P. J. (2017) · The Lancet Psychiatry · doi:10.1016/s2215-0366(17)30015-9 · Cited by 616 · see citing works

An active inference theory of allostasis and interoception in depression

Barrett, L. F., Quigley, K. S., & Hamilton, P. (2016) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2016.0011 · Cited by 554 · see citing works

The Functional and Clinical Significance of the 24-Hour Rhythm of Circulating Glucocorticoids

Oster, H., Challet, E., Ott, V., Arvat, E., de Kloet, E. R., Dijk, D.-J., Lightman, S., Vgontzas, A., & Van Cauter, E. (2017) · Endocrine Reviews · doi:10.1210/er.2015-1080 · Cited by 548 · see citing works

Anxiety disorders

Craske, M. G., Stein, M. B., Eley, T. C., Milad, M. R., Holmes, A., Rapee, R. M., & Wittchen, H.-U. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.24 · Cited by 652 · see citing works

Stress and the brain: Individual variability and the inverted-U

Sapolsky, R. M. (2015) · Nature Neuroscience · doi:10.1038/nn.4109 · Cited by 413 · see citing works

Coping with the Forced Swim Stressor: Towards Understanding an Adaptive Mechanism

de Kloet, E. R., & Molendijk, M. L. (2016) · Neural Plasticity · doi:10.1155/2016/6503162 · Cited by 353 · see citing works

The enteric nervous system relays psychological stress to intestinal inflammation

Schneider, K. M., Blank, N., Alvarez, Y., Thum, K., Lundgren, P., Litichevskiy, L., Sleeman, M., Bahnsen, K., Kim, J., Kardo, S., et al. (2023) · Cell · doi:10.1016/j.cell.2023.05.001 · Cited by 344 · see citing works

Chronic stress and glucocorticoids: From neuronal plasticity to neurodegeneration

Vyas, S., Rodrigues, A. J., Silva, J. M., Tronche, F., Almeida, O. F. X., Sousa, N., & Sotiropoulos, I. (2016) · Neural Plasticity · doi:10.1155/2016/6391686 · Cited by 297 · see citing works

Stress-Induced Metabolic Disorder in Peripheral CD4+ T Cells Leads to Anxiety-like Behavior

Fan, K.-Q., Li, Y.-Y., Wang, H.-L., Mao, X.-T., Guo, J.-X., Wang, F., Huang, L.-J., Li, Y.-N., Ma, X.-Y., Gao, Z.-J., et al. (2019) · Cell · doi:10.1016/j.cell.2019.10.001 · Cited by 312 · see citing works

Current Psychosomatic Practice

Fava, G. A., Cosci, F., & Sonino, N. (2017) · Psychotherapy and Psychosomatics · doi:10.1159/000448856 · Cited by 302 · see citing works

Clinical characterization of allostatic overload

Fava, G. A., McEwen, B. S., Guidi, J., Gostoli, S., Offidani, E., & Sonino, N. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.05.028 · Cited by 265 · see citing works

Neighborhood matters: divergent patterns of stress-induced plasticity across the brain

Chattarji, S., Tomar, A., Suvrathan, A., Ghosh, S., & Rahman, M. M. (2015) · Nature Neuroscience · doi:10.1038/nn.4115 · Cited by 248 · see citing works

Emerging Role for Nucleus Accumbens Medium Spiny Neuron Subtypes in Depression

Francis, T. C., & Lobo, M. K. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.09.007 · Cited by 230 · see citing works

Hierarchical Status Predicts Behavioral Vulnerability and Nucleus Accumbens Metabolic Profile Following Chronic Social Defeat Stress

Larrieu, T., Cherix, A., Duque, A., Rodrigues, J., Lei, H., Gruetter, R., & Sandi, C. (2017) · Current Biology · doi:10.1016/j.cub.2017.06.027 · Cited by 202 · see citing works

The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders

Sanacora, G., Yan, Z., & Popoli, M. (2022) · Nature Reviews Neuroscience · doi:10.1038/s41583-021-00540-x · Cited by 197 · see citing works

Chronic Stress Remodels Synapses in an Amygdala Circuit-Specific Manner

Zhang, J.-Y., Liu, T.-H., He, Y., Pan, H.-Q., Zhang, W.-H., Yin, X.-P., Tian, X.-L., Li, B.-M., Wang, X.-D., Holmes, A., et al. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.06.019 · Cited by 183 · see citing works

Prefrontal cortex executive processes affected by stress in health and disease

Girotti, M., Adler, S. M., Bulin, S. E., Fucich, E. A., Paredes, D., & Morilak, D. A. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.07.004 · Cited by 176 · see citing works

Acetyl- <scp>l</scp> -carnitine deficiency in patients with major depressive disorder

Nasca, C., Bigio, B., Lee, F. S., Young, S. P., Kautz, M. M., Albright, A., Beasley, J., Millington, D. S., Mathé, A. A., Kocsis, J. H., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1801609115 · Cited by 152 · see citing works

Reduced global functional connectivity of the medial prefrontal cortex in major depressive disorder

Murrough, J. W., Abdallah, C. G., Anticevic, A., Collins, K. A., Geha, P., Averill, L. A., Schwartz, J., DeWilde, K. E., Averill, C., Jia‐Wei Yang, G., et al. (2016) · Human Brain Mapping · doi:10.1002/hbm.23235 · Cited by 153 · see citing works

Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice

Higuchi, F., Uchida, S., Yamagata, H., Abe-Higuchi, N., Hobara, T., Hara, K., Kobayashi, A., Shintaku, T., Itoh, Y., Suzuki, T., et al. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.0319-16.2016 · Cited by 158 · see citing works

Stimulus-specific hypothalamic encoding of a persistent defensive state

Kennedy, A., Kunwar, P. S., Li, L.-Y., Stagkourakis, S., Wagenaar, D. A., & Anderson, D. J. (2020) · Nature · doi:10.1038/s41586-020-2728-4 · Cited by 144 · see citing works

The Nucleus Accumbens and Ketamine Treatment in Major Depressive Disorder

Abdallah, C. G., Jackowski, A., Salas, R., Gupta, S., Sato, J. R., Mao, X., Coplan, J. D., Shungu, D. C., & Mathew, S. J. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.49 · Cited by 123 · see citing works

Childhood adversity and epigenetic regulation of glucocorticoid signaling genes: Associations in children and adults

Tyrka, A. R., Ridout, K. K., & Parade, S. H. (2016) · Development and Psychopathology · doi:10.1017/s0954579416000870 · Cited by 119 · see citing works

The neural basis for a persistent internal state in Drosophila females

Deutsch, D., Pacheco, D., Encarnacion-Rivera, L., Pereira, T., Fathy, R., Clemens, J., Girardin, C., Calhoun, A., Ireland, E., Burke, A., et al. (2020) · eLife · doi:10.7554/elife.59502 · Cited by 115 · see citing works

Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress

Nasca, C., Bigio, B., Zelli, D., de Angelis, P., Lau, T., Okamoto, M., Soya, H., Ni, J., Brichta, L., Greengard, P., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.09.020 · Cited by 113 · see citing works

Prefrontal Connectivity and Glutamate Transmission: Relevance to Depression Pathophysiology and Ketamine Treatment

Abdallah, C. G., Averill, C. L., Salas, R., Averill, L. A., Baldwin, P. R., Krystal, J. H., Mathew, S. J., & Mathalon, D. H. (2017) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2017.04.006 · Cited by 111 · see citing works

Perceived Stress in a Gender Perspective: A Survey in a Population of Unemployed Subjects of Southern Italy

Costa, C., Briguglio, G., Mondello, S., Teodoro, M., Pollicino, M., Canalella, A., Verduci, F., Italia, S., & Fenga, C. (2021) · Frontiers in Public Health · doi:10.3389/fpubh.2021.640454 · Cited by 108 · see citing works

Stress-induced remodeling of hippocampal CA3 pyramidal neurons

McEwen, B. S. (2016) · Brain Research · doi:10.1016/j.brainres.2015.12.043 · Cited by 105 · see citing works

Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening

Marcus, D. J., Bedse, G., Gaulden, A. D., Ryan, J. D., Kondev, V., Winters, N. D., Rosas-Vidal, L. E., Altemus, M., Mackie, K., Lee, F. S., et al. (2020) · Neuron · doi:10.1016/j.neuron.2019.12.024 · Cited by 104 · see citing works

Endocannabinoid-Mediated plasticity in nucleus accumbens controls vulnerability to anxiety after social defeat stress

Bosch-Bouju, C., Larrieu, T., Linders, L., Manzoni, O. J., & Layé, S. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.06.082 · Cited by 100 · see citing works

Threat response system: Parallel brain processes in pain vis-à-vis fear and anxiety

Elman, I., & Borsook, D. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00029 · Cited by 100 · see citing works

Molecular basis of dendritic atrophy and activity in stress susceptibility

Francis, T. C., Chandra, R., Gaynor, A., Konkalmatt, P., Metzbower, S. R., Evans, B., Engeln, M., Blanpied, T. A., & Lobo, M. K. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.178 · Cited by 89 · see citing works

Ketamine rapidly reverses stress-induced impairments in GABAergic transmission in the prefrontal cortex in male rodents

Ghosal, S., Duman, C. H., Liu, R.-J., Wu, M., Terwilliger, R., Girgenti, M. J., Wohleb, E., Fogaca, M. V., Teichman, E. M., Hare, B., et al. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.104669 · Cited by 89 · see citing works

Epigenetics, Development, and Psychopathology

O'Donnell, K. J., & Meaney, M. J. (2020) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050718-095530 · Cited by 94 · see citing works

Repeated social stress leads to contrasting patterns of structural plasticity in the amygdala and hippocampus

Patel, D., Anilkumar, S., Chattarji, S., & Buwalda, B. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.03.034 · Cited by 93 · see citing works

Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory

van der Kooij, M. A., Jene, T., Treccani, G., Miederer, I., Hasch, A., Voelxen, N., Walenta, S., & Müller, M. B. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1804412115 · Cited by 92 · see citing works

The pathophysiological impact of stress on the dopamine system is dependent on the state of the critical period of vulnerability

Gomes, F. V., Zhu, X., & Grace, A. A. (2020) · Molecular Psychiatry · doi:10.1038/s41380-019-0514-1 · Cited by 91 · see citing works

Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance

Bigio, B., Mathé, A. A., Sousa, V. C., Zelli, D., Svenningsson, P., McEwen, B. S., & Nasca, C. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1603111113 · Cited by 85 · see citing works

Iatrogenic Factors in Psychopathology

Fava, G. A., & Rafanelli, C. (2019) · Psychotherapy and Psychosomatics · doi:10.1159/000500151 · Cited by 82 · see citing works

Neural stress reactivity relates to smoking outcomes and differentiates between mindfulness and cognitive-behavioral treatments

Kober, H., Brewer, J. A., Height, K. L., & Sinha, R. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2016.09.042 · Cited by 75 · see citing works

A predictive coding framework of allostatic–interoceptive overload in frontotemporal dementia

Migeot, J. A., Duran-Aniotz, C. A., Signorelli, C. M., Piguet, O., & Ibáñez, A. (2022) · Trends in Neurosciences · doi:10.1016/j.tins.2022.08.005 · Cited by 76 · see citing works

Emotion Dysregulation Following Trauma: Shared Neurocircuitry of Traumatic Brain Injury and Trauma-Related Psychiatric Disorders

Weis, C. N., Webb, E. K., deRoon-Cassini, T. A., & Larson, C. L. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.07.023 · Cited by 75 · see citing works

Dynamic stress-related epigenetic regulation of the glucocorticoid receptor gene promoter during early development: The role of child maltreatment

Parent, J., Parade, S. H., Laumann, L. E., Ridout, K. K., Yang, B.-Z., Marsit, C. J., Seifer, R., & Tyrka, A. R. (2017) · Development and Psychopathology · doi:10.1017/s0954579417001298 · Cited by 72 · see citing works

Understanding and Managing Withdrawal Syndromes After Discontinuation of Antidepressant Drugs

Fava, G. A., & Cosci, F. (2019) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.19com12794 · Cited by 69 · see citing works

Portable and wearable real-time stress monitoring: A critical review

Parlak, O. (2021) · Sensors and Actuators Reports · doi:10.1016/j.snr.2021.100036 · Cited by 60 · see citing works

The depressor axis of the renin–angiotensin system and brain disorders: a translational approach

Gironacci, M. M., Vicario, A., Cerezo, G., & Silva, M. G. (2018) · Clinical Science · doi:10.1042/cs20180189 · Cited by 60 · see citing works

Incubation of depression: ECM assembly and parvalbumin interneurons after stress

Spijker, S., Koskinen, M.-K., & Riga, D. (2020) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.07.015 · Cited by 55 · see citing works

Sensory stimulation via the visual, auditory, olfactory and gustatory systems can modulate mood and depression

Canbeyli, R. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15507 · Cited by 48 · see citing works

The pubertal stress recalibration hypothesis: Potential neural and behavioral consequences

DePasquale, C. E., Herzberg, M. P., & Gunnar, M. R. (2021) · Child Development Perspectives · doi:10.1111/cdep.12429 · Cited by 44 · see citing works

Expression of the PPM1F Gene Is Regulated by Stress and Associated with Anxiety and Depression

Wingo, A. P., Velasco, E. R., Florido, A., Lori, A., Choi, D. C., Jovanovic, T., Ressler, K. J., & Andero, R. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.08.013 · Cited by 44 · see citing works

Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p Is Associated with Modulation of BDNF and FKBP5 in Brain Areas of PTSD-Related Susceptible and Resilient Mice

Maurel, O. M., Torrisi, S. A., Barbagallo, C., Purrello, M., Salomone, S., Drago, F., Ragusa, M., & Leggio, G. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22105157 · Cited by 44 · see citing works

Immunometabolic dysregulation is associated with reduced cortical thickness of the anterior cingulate cortex

van Velzen, L. S., Schmaal, L., Milaneschi, Y., van Tol, M.-J., van der Wee, N. J. A., Veltman, D. J., & Penninx, B. W. J. H. (2017) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2016.10.019 · Cited by 38 · see citing works

miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment with ketamine

Mingardi, J., La Via, L., Tornese, P., Carini, G., Trontti, K., Seguini, M., Tardito, D., Bono, F., Fiorentini, C., Elia, L., et al. (2021) · Neurobiology of Stress · doi:10.1016/j.ynstr.2021.100381 · Cited by 36 · see citing works

Altered resting-state neural networks in children and adolescents with functional neurological disorder

Rai, S., Foster, S., Griffiths, K. R., Breukelaar, I. A., Kozlowska, K., & Korgaonkar, M. S. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103110 · Cited by 35 · see citing works

Impact of Acute and Chronic Cannabis Use on Stress Response Regulation: Challenging the Belief That Cannabis Is an Effective Method for Coping

al'Absi, M., & Allen, A. M. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.687106 · Cited by 34 · see citing works

Intrinsic timescales and predictive allostatic interoception in brain health and disease

Ibanez, A., & Northoff, G. (2024) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105510 · Cited by 36 · see citing works

Acute stress and alcohol exposure during adolescence result in an anxious phenotype in adulthood: Role of altered glutamate/endocannabinoid transmission mechanisms

Sánchez-Marín, L., Flores-López, M., Pastor, A., Gavito, A. L., Suárez, J., de la Torre, R., Pavón, F. J., Rodríguez de Fonseca, F., & Serrano, A. (2022) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2021.110460 · Cited by 33 · see citing works

Perinatal stress and epigenetics.

(2021) · Handbook of Clinical Neurology · doi:10.1016/b978-0-12-820107-7.00008-2 · Cited by 28 · see citing works

A Randomized Controlled Trial of a Mindfulness-Based Weight Loss Intervention on Cardiovascular Reactivity to Social-Evaluative Threat Among Adults with Obesity

Daubenmier, J., Epel, E. S., Moran, P. J., Thompson, J., Mason, A. E., Acree, M., Goldman, V., Kristeller, J., Hecht, F. M., & Mendes, W. B. (2019) · Mindfulness · doi:10.1007/s12671-019-01232-5 · Cited by 27 · see citing works

Therapeutic role of long non-coding RNA TCONS_00019174 in depressive disorders is dependent on Wnt/β-catenin signaling pathway

Ni, X., Liao, Y., Li, L., Zhang, X., & Wu, Z. (2018) · Journal of Integrative Neuroscience · doi:10.3233/jin-170052 · Cited by 26 · see citing works

Putative neural consequences of captivity for elephants and cetaceans

Jacobs, B., Rally, H., Doyle, C., O’Brien, L., Tennison, M., & Marino, L. (2022) · Reviews in the Neurosciences · doi:10.1515/revneuro-2021-0100 · Cited by 25 · see citing works

Allostasis, health, and development in Latin America

Migeot, J., Panesso, C., Duran-Aniotz, C., Ávila-Rincón, C., Ochoa, C., Huepe, D., Santamaría-García, H., Miranda, J. J., Escobar, M. J., Pina-Escudero, S., et al. (2024) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105697 · Cited by 25 · see citing works

Epigenetic mechanisms within the cingulate cortex regulate innate anxiety-like behavior

Sah, A., Sotnikov, S., Kharitonova, M., Schmuckermair, C., Diepold, R. P., Landgraf, R., Whittle, N., & Singewald, N. (2019) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyz004 · Cited by 24 · see citing works

The effect of childhood trauma on serum BDNF in bipolar depression is modulated by the serotonin promoter genotype

Benedetti, F., Ambrée, O., Locatelli, C., Lorenzi, C., Poletti, S., Colombo, C., & Arolt, V. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.07.043 · Cited by 18 · see citing works

Chronic Stress Induces Coordinated Cortical Microcircuit Cell–Type Transcriptomic Changes Consistent With Altered Information Processing

Newton, D. F., Oh, H., Shukla, R., Misquitta, K., Fee, C., Banasr, M., & Sibille, E. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.10.015 · Cited by 19 · see citing works

Restraint Stress in Mice Alters Set of 25 miRNAs Which Regulate Stress- and Depression-Related mRNAs

Solich, J., Kuśmider, M., Faron-Górecka, A., Pabian, P., & Dziedzicka-Wasylewska, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249469 · Cited by 13 · see citing works

Allostatic interoception and brain health: From neurodegeneration to social adversities

Migeot, J., & Ibáñez, A. (2025) · Encyclopedia of the Human Brain · doi:10.1016/b978-0-12-820480-1.00025-5 · Cited by 10 · see citing works

Global Adversities, the Media, and Mental Health

Kesner, L., & Horáček, J. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.809239 · Cited by 9 · see citing works

ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ

Атабекова, Б. Б. (2024) · Habaršy. Pedagogika ġylymdary seriâsy · doi:10.51889/2959-5762.2023.80.4.019

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

The Neuroscientist Comments

(2019) · The Neuroscientist · doi:10.1177/1073858419859506

The ethical neuroscientist

(2008) · Nature Neuroscience · doi:10.1038/nn0308-239 · Cited by 6 · see citing works

The Neuroscientist Comments

(2009) · The Neuroscientist · doi:10.1177/1073858409338132