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The Emerging Global Epidemic of Type 1 Diabetes

Tuomilehto, Jaakko·2013·Current Diabetes Reports

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Abstract

Type 1 diabetes mellitus (T1D) can occur at any age, with a peak in incidence around puberty. Classification between T1D and type 2 diabetes becomes more challenging with increasing age of onset of T1D over time develops in genetically predisposed individuals. The main susceptibility is conferred with human leukocyte antigen (HLA) genes. Some of the geographic variation in incidence and familial aggregation is explained by differences in HLA haplotypes. In many populations, the incidence is somewhat higher in males than in females, and a 1.3- to 2.0-fold male excess in incidence after about 15 years of age exists in most populations. The incidence of childhood-onset T1D varies markedly among countries. East Asian and native American populations have low incidences (approximately 0.1-8 per 100 000/year), while the highest rates are found in Finland (>60 per 100 000/year), Sardinia (40 per 100 000/year), and Sweden (47 per 100 000/year). The risk is highest in European-derived populations. About 10 %-20 % of newly diagnosed childhood cases of T1D have an affected first-degree relative. Those with an affected sibling or parent have a cumulative risk of 3 %-7 % up to about 20 years of age, as compared with <1 % in the general population. The cumulative incidence among the monozygotic co-twins of persons with T1D is less than 50 %. Thus, the majority of genetically predisposed people do not develop T1D. Studies assessing temporal trends have shown that the incidence of childhood-o…

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature · doi:10.1038/nature05911 · Cited by 9,442
Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study
Patterson, C. C., Dahlquist, G. G., Gyürüs, E., Green, A., & Soltész, G. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60568-7 · Cited by 1,854
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
The Type 1 Diabetes Genetics Consortium, Barrett, J. C., Clayton, D. G., Concannon, P., Akolkar, B., Cooper, J. D., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., et al. (2009) · Nature Genetics · doi:10.1038/ng.381 · Cited by 1,746
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
Finland, G. O. T. 1. D. I., Todd, J. A., the Wellcome Trust Case Control Consortium, Walker, N. M., Cooper, J. D., Smyth, D. J., Downes, K., Plagnol, V., Bailey, R., Nejentsev, S., et al. (2007) · Nature Genetics · doi:10.1038/ng2068 · Cited by 1,456
Incidence and trends of childhood type 1 diabetes worldwide 1990–1999
The DIAMOND Project Group (2006) · Diabetic Medicine · doi:10.1111/j.1464-5491.2006.01925.x · Cited by 1,085
Worldwide increase in incidence of Type I diabetes – the analysis of the data on published incidence trends
Onkamo, P., Väänänen, S., Karvonen, M., & Tuomilehto, J. (1999) · Diabetologia · doi:10.1007/s001250051309 · Cited by 984
Self-citation
Diabetes in sub-Saharan Africa
Mbanya, J. C., Motala, A. A., Sobngwi, E., Assah, F. K., & Enoru, S. T. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60550-8 · Cited by 805
The rise of childhood type 1 diabetes in the 20th century.
Gale, E. (2002) · Diabetes · doi:10.2337/diabetes.51.12.3353 · Cited by 673
Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study
Harjutsalo, V., Sjöberg, L., & Tuomilehto, J. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60765-5 · Cited by 666
Self-citation
Projections of Type 1 and Type 2 Diabetes Burden in the U.S. Population Aged <20 Years Through 2050
Imperatore, G., Boyle, J. P., Thompson, T. J., Case, D., Dabelea, D., Hamman, R. F., Lawrence, J. M., Liese, A. D., Liu, L. L., Mayer‐Davis, E. J., et al. (2012) · Diabetes Care · doi:10.2337/dc12-0669 · Cited by 509
Genetics of the HLA Region in the Prediction of Type 1 Diabetes
Noble, J. A., & Valdes, A. M. (2011) · Current Diabetes Reports · doi:10.1007/s11892-011-0223-x · Cited by 499
Management of dyslipidemia in children and adolescents with diabetes
American Diabetes Association (2003) · Diabetes Care · doi:10.2337/diacare.26.7.2194 · Cited by 438
Epidemiologic Approach to the Etiology of Type I Diabetes Mellitus and Its Complications
Flier, J. S., Underhill, L. H., Królewski, A. S., Warram, J. H., Rand, L. I., & Kahn, C. R. (1987) · New England Journal of Medicine · doi:10.1056/nejm198711263172206 · Cited by 414
Latent autoimmune diabetes in adults (LADA) should be less latent
Fourlanos, S., Dotta, F., Greenbaum, C. J., Palmer, J. P., Rolandsson, O., Colman, P. G., & Harrison, L. C. (2005) · Diabetologia · doi:10.1007/s00125-005-1960-7 · Cited by 411
Incidence of childhood-onset insulin-dependent diabetes mellitus: the EURODIAB ACE Study
Green, A., Gale, E. A. M., & Patterson, C. C. (1992) · The Lancet · doi:10.1016/0140-6736(92)90938-y · Cited by 407
Genetic Liability of Type 1 Diabetes and the Onset Age Among 22,650 Young Finnish Twin Pairs
Harjutsalo, V., Kaprio, J. A., Kinnunen, L., Koskenvuo, M. J., & Tuomilehto, J. (2003) · Diabetes · doi:10.2337/diabetes.52.4.1052 · Cited by 392
Self-citation
Differences in Risk of Insulin-Dependent Diabetes in Offspring of Diabetic Mothers and Diabetic Fathers
Warram, J. H., Królewski, A. S., Gottlieb, M. S., & Kahn, C. R. (1984) · New England Journal of Medicine · doi:10.1056/nejm198407193110304 · Cited by 392
A review of the recent epidemiological data on the worldwide incidence of Type 1 (insulin-dependent) diabetes mellitus
Karvonen, M., Tuomilehto, J., Libman, I. M., & Laporte, R. E. (1993) · Diabetologia · doi:10.1007/bf02374468 · Cited by 380
Self-citation
Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins
Kyvik, K. O., Green, A., & Beck‐Nielsen, H. (1995) · BMJ · doi:10.1136/bmj.311.7010.913 · Cited by 357
Adult-Onset Autoimmune Diabetes in Europe Is Prevalent With a Broad Clinical Phenotype
Hawa, M. I., Kolb, H., Schloot, N., Beyan, H., Paschou, S. A., Buzzetti, R., Mauricio, D., De Leiva, A., Yderstraede, K., Beck-Neilsen, H., et al. (2013) · Diabetes Care · doi:10.2337/dc12-0931 · Cited by 339
Self-citation
Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States
Redondo, M. J., Yu, L., Hawa, M., Mackenzie, T., Pyke, D. A., Eisenbarth, G. S., & Leslie, R. D. G. (2001) · Diabetologia · doi:10.1007/s001250051626 · Cited by 322
In the absence of renal disease, 20 year mortality risk in type 1 diabetes is comparable to that of the general population: a report from the Pittsburgh Epidemiology of Diabetes Complications Study
Orchard, T. J., Secrest, A. M., Miller, R. G., & Costacou, T. (2010) · Diabetologia · doi:10.1007/s00125-010-1860-3 · Cited by 317
Narrative Review: Ketosis-Prone Type 2 Diabetes Mellitus
Umpierrez, G. E., Smiley, D., & Kitabchi, A. E. (2006) · Annals of Internal Medicine · doi:10.7326/0003-4819-144-5-200603070-00011 · Cited by 299
Diabetes care in sub-Saharan Africa
Beran, D., & Yudkin, J. S. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69704-3 · Cited by 266
Incidence of Type 1 Diabetes in Finland
Harjutsalo, V., Sund, R., Knip, M., & Groop, P. (2013) · JAMA · doi:10.1001/jama.2013.8399 · Cited by 263
A sub-Saharan African perspective of diabetes
Gill, G. V., Mbanya, J. C., Ramaiya, K. L., & Tesfaye, S. H. (2008) · Diabetologia · doi:10.1007/s00125-008-1167-9 · Cited by 242
Thirty Years of Prospective Nationwide Incidence of Childhood Type 1 Diabetes
Berhan, Y., Waernbaum, I., Lind, T., Möllsten, A., Dahlquist, G., & for the Swedish Childhood Diabetes Study Group* (2011) · Diabetes · doi:10.2337/db10-0813 · Cited by 237
The incidence of Type I diabetes has not increased but shifted to a younger age at diagnosis in the 0–34 years group in Sweden 1983 to 1998
and the Swedish Childhood Diabetes Study Group, Pundziute-Lyckå, A., Dahlquist, G., Nyström, L., Arnqvist, H., Björk, E., Blohmé, G., Bolinder, J., Eriksson, J., Sundkvist, G., et al. (2002) · Diabetologia · doi:10.1007/s00125-002-0845-2 · Cited by 234
Syndromes of ketosis-prone diabetes mellitus
Balasubramanyam, A., Nalini, R., Hampe, C. S., & Maldonado, M. (2008) · Endocrine Reviews · doi:10.1210/er.2007-0026 · Cited by 200
Etiological Approach to Characterization of Diabetes Type
Dabelea, D., Pihoker, C., Talton, J. W., D’Agostino, R. B., Fujimoto, W. Y., KLINGENSMITH, G. J., Lawrence, J. M., Linder, B. L., Marcovina, S. M., Mayer‐Davis, E. J., et al. (2011) · Diabetes Care · doi:10.2337/dc10-2324 · Cited by 190
Incidence of Type 1 and Type 2 Diabetes in Adults Aged 30–49 Years
Bruno, G., Runzo, C., Cavallo‐Perin, P., Merletti, F., Rivetti, M., Pinach, S., Novelli, G., Trovati, M., Cerutti, F., Pagano, G., et al. (2005) · Diabetes Care · doi:10.2337/diacare.28.11.2613 · Cited by 187
Record-high incidence of Type I (insulin-dependent) diabetes mellitus in Finnish children
Tuomilehto, J., Karvonen, M., Pitkäniemi, J. M., Virtala, E. T., Kohtamäki, K., Toivanen, L., & Tuomilehto‐Wolf, E. (1999) · Diabetologia · doi:10.1007/s001250051212 · Cited by 174
Self-citation
The onset age of type 1 diabetes in Finnish children has become younger. The Finnish Childhood Diabetes Registry Group.
Karvonen, M., Pitkäniemi, J. M., & Tuomilehto, J. (1999) · Diabetes Care · doi:10.2337/diacare.22.7.1066 · Cited by 171
Self-citation
North-American Twins With IDDM: Genetic, Etiological, and Clinical Significance of Disease Concordance According to Age, Zygosity, and the Interval After Diagnosis in First Twin
Kumar, D., Gemayel, N. S., Deapen, D., Kapadia, D., Yamashita, P. H., Lee, M., Dwyer, J. H., Roy‐Burman, P., Bray, G. A., & Mack, T. M. (1993) · Diabetes · doi:10.2337/diab.42.9.1351 · Cited by 158
THE EPIDEMIOLOGY OF INSULIN DEPENDENT DIABETES, WITH PARTICULAR REFERENCE TO THE RELATIONSHIP OF VIRUS INFECTION TO ITS ETIOLOGY
Gamble, D. R. (1980) · Epidemiologic Reviews · doi:10.1093/oxfordjournals.epirev.a036226 · Cited by 157
The epidemiology of type 1 diabetes mellitus is not the same in young adults as in children
Kyvik, K. O., Nystrom, L., Gorus, F., Songini, M., Oestman, J., Castell, C., Green, A., Guyrus, E., Ionescu-Tirgoviste, C., McKinney, P. A., et al. (2004) · Diabetologia · doi:10.1007/s00125-004-1331-9 · Cited by 150
The Incidence of Type 1 Diabetes in the Age Group 0–39 Years Has Not Increased in Antwerp (Belgium) Between 1989 and 2000
Weets, I., De Leeuw, I. H., Du Caju, M. V. L., Rooman, R., Keymeulen, B., Mathieu, C., Rottiers, R., Daubresse, J.-C., Rocour-Brumioul, D., Pipeleers, D. G., et al. (2002) · Diabetes Care · doi:10.2337/diacare.25.5.840 · Cited by 137
Diabetes classification: grey zones, sound and smoke: Action LADA 1
Leslie, R. D. G., Kolb, H., Schloot, N. C., Buzzetti, R., Mauricio, D., De Leiva, A., Yderstraede, K., Sarti, C., Thivolet, C., Hadden, D., et al. (2008) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.877 · Cited by 136
Improved motor development and good long-term glycaemic control with sulfonylurea treatment in a patient with the syndrome of intermediate developmental delay, early-onset generalised epilepsy and neonatal diabetes associated with the V59M mutation in the KCNJ11 gene
Slingerland, A. S., Nuboer, R., Hadders‐Algra, M., Hattersley, A. T., & Bruining, G. J. (2006) · Diabetologia · doi:10.1007/s00125-006-0407-0 · Cited by 128
High Familial Risk and Genetic Susceptibility in Early Onset Childhood Diabetes
Gillespie, K. M., Gale, E. A., & Bingley, P. J. (2002) · Diabetes · doi:10.2337/diabetes.51.1.210 · Cited by 126
HLA complex genes in type 1 diabetes and other autoimmune diseases. Which genes are involved?
Undlien, D. E., Lie, B. A., & Thorsby, E. (2001) · Trends in Genetics · doi:10.1016/s0168-9525(00)02180-6 · Cited by 122
Differential Transmission of Type 1 Diabetes from Diabetic Fathers and Mothers to Their Offspring
Harjutsalo, V., Reunanen, A., & Tuomilehto, J. O. (2006) · Diabetes · doi:10.2337/db05-1296 · Cited by 115
Self-citation
Long-term risk of IDDM in first-degree relatives of patients with IDDM
Lorenzen, T., Pociot, F., Hougaard, P., & Nerup, J. (1994) · Diabetologia · doi:10.1007/bf00398061 · Cited by 109
Increase in Incidence of Insulin-Dependent Diabetes Mellitus among Children in Finland
Tuomilehto, J. O., Virtala, E. T., Karvonen, M., Lounamaa, R., PITKĀNIEMI, J., Reunanen, A., Tuomilehto‐Wolf, E., & Toivanen, L. (1995) · International Journal of Epidemiology · doi:10.1093/ije/24.5.984 · Cited by 105
Self-citation
Decline of mumps antibodies in Type 1 (insulin-dependent) diabetic children and a plateau in the rising incidence of Type 1 diabetes after introduction of the mumps-measles-rubella vaccine in Finland
Hy�ty, H., Hiltunen, M., Reunanen, A., Leinikki, P., Vesikari, T., Lounamaa, R., Tuomilehto, J., �kerblom, H. K., the Childhoood Diabetes in Finland Study Group, Toivanen, L., et al. (1993) · Diabetologia · doi:10.1007/bf00400810 · Cited by 104
Self-citation
The prenatal environment and type 1 diabetes
Stene, L. C., & Gale, E. A. M. (2013) · Diabetologia · doi:10.1007/s00125-013-2929-6 · Cited by 102
A high incidence of type 1 diabetes and an alarming increase in the incidence of type 2 diabetes among young adults in Finland between 1992 and 1996
Lammi, N., Taskinen, O., Moltchanova, E. V., Notkola, I. ‐., Eriksson, J. G., Tuomilehto, J., & Karvonen, M. (2007) · Diabetologia · doi:10.1007/s00125-007-0690-4 · Cited by 97
Self-citation
Correlations between the incidence of childhood-onset Type I diabetes in Europe and HLA genotypes
Rønningen, K. S., Keiding, N., Green, A., & on behalf of Genomic Marker Contributors and the EURODIAB ACE Study Group (2001) · Diabetologia · doi:10.1007/pl00002955 · Cited by 94
Diabetes in Africans. Part 2: Ketosis-prone atypical diabetes mellitus.
Sobngwi, E., Mauvais‐Jarvis, F., Vexiau, P., Mbanya, J. C., & Gautier, J. F. (2002) · PubMed · Cited by 90
Spring harvest? Reflections on the rise of type 1 diabetes
Gale, E. A. M. (2005) · Diabetologia · doi:10.1007/s00125-005-0028-z · Cited by 90
Type 1 diabetes in Yorkshire, UK: time trends in 0–14 and 15–29‐year‐olds, age at onset and age‐period‐cohort modelling
Feltbower, R. G., McKinney, P. A., Parslow, R. C., Stephenson, C. R., & Bodansky, H. J. (2003) · Diabetic Medicine · doi:10.1046/j.1464-5491.2003.00960.x · Cited by 87
Evidence for importance of gender and birth cohort for risk of IDDM in offspring of IDDM parents
Tuomilehto, J. O., Podar, T., Tuomilehto‐Wolf, E., & Virtala, E. T. (1995) · Diabetologia · doi:10.1007/bf00400588 · Cited by 87
Self-citation
Diabetic ketoacidosis in Denmark
Henriksen, O. M., Røder, M. E., Prahl, J. B., & Svendsen, O. L. (2006) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2006.07.024 · Cited by 85
Cumulative Incidence of Type 1 Diabetes in 10,168 Siblings of Finnish Young-Onset Type 1 Diabetic Patients
Harjutsalo, V., Podar, T., & Tuomilehto, J. O. (2005) · Diabetes · doi:10.2337/diabetes.54.2.563 · Cited by 82
Self-citation
Increasing Incidence and Age at Diagnosis among Children with Type 1 Diabetes Mellitus over a 20-Year Period in Auckland (New Zealand)
Derraik, J. G. B., Reed, P., Jefferies, C., Cutfield, S. W., Hofman, P. L., & Cutfield, W. S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032640 · Cited by 77
Incidence Data of Childhood-Onset Type I Diabetes in France During 1988-1997: The Case for a Shift Toward Younger Age at Onset
Charkaluk, M., Czernichow, P., & Lévy‐Marchal, C. (2002) · Pediatric Research · doi:10.1203/00006450-200212000-00008 · Cited by 76
Incidence of Insulin‐Dependent Diabetes Mellitus (0–29 Years at Onset) in Denmark
Christau, B., Kromann, H., Christy, M., Andersen, O. O., & Nerup, J. (1979) · Acta Medica Scandinavica · doi:10.1111/j.0954-6820.1979.tb00719.x · Cited by 74
Genetic susceptibility to non-insulin dependent diabetes mellitus and glucose intolerance are located in HLA region.
Tuomilehto‐Wolf, E., Tuomilehto, J., Hitman, G. A., Nissinen, A. E. T., Stengård, J., Pekkanen, J., Kivinen, P., Kaarsalo, E., & Karvonen, M. J. (1993) · BMJ · doi:10.1136/bmj.307.6897.155 · Cited by 73
Self-citation
Islet cell and glutamic acid decarboxylase antibodies present at diagnosis of diabetes predict the need for insulin treatment. A cohort study in young adults whose disease was initially labeled as type 2 or unclassifiable diabetes.
Littorin, B., Sundkvist, G., Hagopian, W., Landin-Olsson, M., Lernmark, A., Ostman, J., Arnqvist, H. J., Blohmé, G., Bolinder, J., Eriksson, J. W., et al. (1999) · Diabetes Care · doi:10.2337/diacare.22.3.409 · Cited by 72
When is an epidemic an epidemic?
Green, M. S., Swartz, T. A., Mayshar, E., Lev, B. I., Leventhal, A., Slater, P. E., & Shemer, J. (2002) · PubMed · Cited by 68
Fertility in people with childhood-onset type 1 diabetes
Sjöberg, L., Pitkäniemi, J. M., Haapala, L., Kaaja, R., & Tuomilehto, J. O. (2012) · Diabetologia · doi:10.1007/s00125-012-2731-x · Cited by 62
Self-citation
Diabetes in tropical Africa: a prospective study, 1981-7. I. Characteristics of newly presenting patients in Dar es Salaam, Tanzania, 1981-7.
Swai, A. B. M., Lutale, J., & McLarty, D. G. (1990) · BMJ · doi:10.1136/bmj.300.6732.1103 · Cited by 59
Signs of β-Cell Autoimmunity in Nondiabetic Schoolchildren
Kondrashova, A., Viskari, H., Kulmala, P., Romanov, A., Ilonen, J., Hyöty, H., & Knip, M. (2007) · Diabetes Care · doi:10.2337/dc06-0711 · Cited by 58
The age of onset and sex distribution of insulin-dependent diabetes mellitus in Africans in South Africa
Kalk, W. J., Huddle, K., & Raal, F. J. (1993) · Postgraduate Medical Journal · doi:10.1136/pgmj.69.813.552 · Cited by 57
Marked temporal increase in the incidence of type 1 and type 2 diabetes among young adults in Finland
Lammi, N., Blomstedt, P., Moltchanova, E. V., Eriksson, J. G., Tuomilehto, J. O., & Karvonen, M. (2008) · Diabetologia · doi:10.1007/s00125-008-0952-9 · Cited by 57
Self-citation
The incidence of Type 1 (insulin-dependent) diabetes mellitus 15?29 years in Norway 1978?1982
Joner, G., & S�vik, O. (1991) · Diabetologia · doi:10.1007/bf00405087 · Cited by 57
The Clinical Pattern of Diabetes Mellitus in Ethiopians
Lester, F. T. (1984) · Diabetes Care · doi:10.2337/diacare.7.1.6 · Cited by 52
Pathogenesis of Type 1 and Type 2 Diabetes Mellitus in Sub-Saharan Africa: Implications for Transitional Populations
Osei, K., Schuster, D. P., Amoah, A. G. B., & Owusu, S. (2003) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1177/174182670301000203 · Cited by 50
Difficulties in Classifying Diabetes at Presentation in the Young Adult
Arnqvist, H. J., Littorin, B., Nyström, L., Scherstén, B., Östman, J., Blohmé, G., Lithner, F., & Wibell, L. B. (1993) · Diabetic Medicine · doi:10.1111/j.1464-5491.1993.tb00132.x · Cited by 49
Increasing trend of Type I diabetes in children and young adults in the province of Turin (Italy). Analysis of age, period and birth cohort effects from 1984 to 1996
Bruno, G., Merletti, F., Biggeri, A., Cerutti, F., Grosso, N., Salvia, A. D., Vitali, E., & Pagano, G. (2001) · Diabetologia · doi:10.1007/s001250051575 · Cited by 49
Challenges in Diagnosing Type 1 Diabetes in Different Populations
Rewers, M. (2012) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2012.36.2.90 · Cited by 49
Rising Rates of All Types of Diabetes in South Asian and Non-South Asian Children and Young People Aged 0–29 Years in West Yorkshire, U.K., 1991–2006
Harron, K. L., Feltbower, R. G., McKinney, P. A., Bodansky, H. J., Campbell, F., & Parslow, R. C. (2011) · Diabetes Care · doi:10.2337/dc10-1512 · Cited by 48
Prevalence and clinical picture of IDDM in Nigerian Igbo schoolchildren
Afoke, A. O., Ejeh, N. M., Nwonu, E. N., Okafor, C. O., Udeh, N. J., & Ludvigsson, J. (1992) · Diabetes Care · doi:10.2337/diacare.15.10.1310 · Cited by 48
Prevalence of IDDM in Schoolchildren in Khartoum, Sudan
Elamin, A., Omer, M., Hofvander, Y., & Tuvemo, T. (1989) · Diabetes Care · doi:10.2337/diacare.12.6.430 · Cited by 47
Current clinical status, glucose control, and complication rates of children and youth with type 1 diabetes in Rwanda
Marshall, S. L., Edidin, D. V., Sharma, V., Ogle, G. D., Arena, V. C., & Orchard, T. J. (2012) · Pediatric Diabetes · doi:10.1111/pedi.12007 · Cited by 46
Recent incidence of type 1 diabetes mellitus in children 0–14 years in Newfoundland and Labrador, Canada climbs to over 45/100,000: a retrospective time trend study
Newhook, L. A., Penney, S., Fiander, J., & Dowden, J. (2012) · BMC Research Notes · doi:10.1186/1756-0500-5-628 · Cited by 44
Diabetes in Africa. Pathogenesis of type 1 and type 2 diabetes mellitus in sub-Saharan Africa: implications for transitional populations.
Osei, K., Schuster, D. P., Amoah, A. G. B., & Owusu, S. (2003) · PubMed · doi:10.1097/01.hjr.0000060841.48106.a3 · Cited by 44
Incidence of Type 1 Diabetes in Lithuanians Aged 0–39 Years Varies by the Urban-Rural Setting, and the Time Change Differs for Men and Women During 1991–2000
Pundziūtė-Lyckå, A., Urbonaitė, B., Ostrauskas, R., Zalinkevicius, R., & Dahlquist, G. G. (2003) · Diabetes Care · doi:10.2337/diacare.26.3.671 · Cited by 42
Incidence of Type 1 Diabetes in Philadelphia Is Higher in Black Than White Children From 1995 to 1999
Lipman, T. H., Jawad, A. F., Murphy, K. M., Tuttle, A., Thompson, R. L., Ratcliffe, S. J., & Katz, L. E. L. (2006) · Diabetes Care · doi:10.2337/dc06-0517 · Cited by 39
The incidence of type 1 diabetes in young Czech children stopped rising
Cinek, O., Kulich, M., & Šumnı́k, Z. (2012) · Pediatric Diabetes · doi:10.1111/j.1399-5448.2012.00858.x · Cited by 35
HLA haplotypes in Type 1 (insulin-dependent) diabetes mellitus: molecular analysis of the HLA-DQ locus
Tienari, P. J., Tuomilehto‐Wolf, E., Tuomilehto, J., Peltonen, L., �kerblom, H. K., Fagerlund, Å., Flittner, M., Gustafsson, B., Hakulinen, A., Herva, L., et al. (1992) · Diabetologia · doi:10.1007/bf00400926 · Cited by 30
Self-citation
IDDM Incidence in a Multiracial Population: The Hawaii IDDM Registry, 1980–1990
Patrick, S. L., Kadohiro, J. K., Waxman, S. H., Curb, J. D., Orchard, T. J., Dorman, J. S., Kuller, L. H., & LaPorte, R. E. (1997) · Diabetes Care · doi:10.2337/diacare.20.6.983 · Cited by 24
How to survive diabetes
Gale, E. A. M. (2009) · Diabetologia · doi:10.1007/s00125-009-1275-1 · Cited by 20
Incidence of IDDM in the Province Of Rzeszów, Poland, 0- to 29-Year-Old Age-Group, 1980–1992
Grzywa, M., & Sobel, A. (1995) · Diabetes Care · doi:10.2337/diacare.18.4.542 · Cited by 18
HLA Antigens in Insulin-Dependent Diabetes Mellitus
Tuomilehto‐Wolf, E., & Tuomilehto, J. (1991) · Annals of Medicine · doi:10.3109/07853899109150507 · Cited by 18
Self-citation
Patterns of diabetes mellitus in young Africans and Indians in Natal.
Omar, M. A., & Asmal, A. C. (1984) · PubMed · Cited by 18
The rising incidence of type 1 diabetes in the northeastern part of Thailand.
Panamonta, O., Thamjaroen, J., Panamonta, M., Panamonta, N., & Suesirisawat, C. (2011) · PubMed · Cited by 17
East Africans in Sweden Have a High Risk for Type 1 Diabetes
Hjern, A., Söderström, U., & Åman, J. (2012) · Diabetes Care · doi:10.2337/dc11-1536 · Cited by 13
Epidemiology of Type 1 Diabetes
Stene, L. C., & Tuomilehto, J. (2016) · Wiley eBooks · doi:10.1002/9781118924853.ch3 · Cited by 7
Self-citation
Untitled work
Karvonen (1997) · doi:10.1002/(sici)1099-0895(199712)13:4
Self-citation

Research works printed but not linked: 2

•• International Diabetes Feferation. IDF Diabetes Atlas. 5th edition. Brussels 2012. IDF updates the global estimates for each country nowadays every year and provides projections for the future numbers of people with diabetes in the world. A very important and useful document.
Miettinen M, Kinnunen L, Keinänen-Kiukaanniemi S, et al. Prevalence of vitamin D insufficiency in Finnish adult population. Suomen Lääkäril. 2013;68:29–33. in Finnish with English Summary.

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See all 292

Authors: Tuomilehto, J.
Affiliations: Universität für Weiterbildung Krems (AT)
Corresponding author: Tuomilehto, Jaakko
ORCID: Tuomilehto, Jaakko
Venue: Current Diabetes Reports
Publisher: Springer Science and Business Media LLC
Published: 2013-09-27
Volume: 13
Issue: 6
Pages: 795-804
ISSN: 1534-4827 (ISSN-L)
1539-0829
DOI: 10.1007/s11892-013-0433-5
OpenAlex: W1997449038
Cited by: 292
References: 92
Citations by year: 2026: 6 · 2025: 15 · 2024: 13 · 2023: 27 · 2022: 31 · 2021: 21 · 2020: 32 · 2019: 26 · 2018: 29 · 2017: 32 · 2016: 25 · 2015: 18 · 2014: 17
FWCI: 13.26
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Current Diabetes Reports (publishedVersion)
PubMed (publishedVersion)
STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
WOS
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Keywords: type 1 diabetes, diabetes incidence, childhood-onset diabetes, HLA haplotypes, genetic susceptibility, familial aggregation, sex differences in incidence, geographic variation in incidence, incidence trends, age of onset, environmental risk factors
MeSH terms: Diabetes Mellitus, Type 1, Female, Humans, Male, Incidence, Age of Onset, Age Distribution, Sex Distribution

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The Emerging Global Epidemic of Type 1 Diabetes

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