Mental fatigue and negative emotion among nurses during the COVID-19 pandemic
Open accessAbstract
COVID-19 is a major public health event affecting the people worldwide. Nurses are still under immense psychological pressure. This study aimed to explore the relationship between mental fatigue and negative emotions among frontline medical staff during the COVID-19 pandemic. The study was conducted in August 2020, which included 419 medical staff between 17 to 28 years. The Fatigue Scale, Multidimensional Mental Flexibility Questionnaire, Cognitive Fusion Scale, and Depression-Anxiety-Stress Brief Version Scale were used. During the data collection period, the pandemic was under control in China and continued worldwide. The results indicated that 27.7% of the medical staff experienced depression, and 32.3% of them feel stressed. Specifically, first, correlation analyses showed significant positive pairwise correlations between mental fatigue, psychological inflexibility, cognitive fusion, and negative emotions among nurses. Second, mediation model tests showed statistically significant mediating effects of psychological inflexibility and cognitive fusion between mental fatigue on nurses' negative emotions, and statistically, significant chain mediating effects of psychological inflexibility and cognitive fusion. Mental fatigue indirectly affects nurses' negative effects through the mediating effects of psychological inflexibility, cognitive fusion, and the chain mediating effects of psychological inflexibility and cognitive fusion, respectively. the negative effects of mental fatigue come from impairment of cognitive functioning, and interventions using acceptance and commitment therapy for mental fatigue and negative emotions are more effective since both psychological inflexibility and cognitive fusion are important components of the therapy. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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Claims the paper makes
6 of 14 cited sources checked · 3 supported · 0 flagged · accuracy not yet measured
- Premisecitation
High cognitive fusion is linked to worse emotion regulation, including mood disorders.
“excessive cognitive fusion implies poorer emotion regulation, such as mood disorders (Wersebe et al., 2018).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Wersebe et al., 2018 source
The Measures section lists defusion as one component of psychological flexibility, and the Results link increased psychological flexibility to improved emotional well-being during the intervention. Neither passage establishes that high cognitive fusion is linked to poorer emotion regulation or mood disorders. Searches for cognitive fusion and emotion regulation found no passage addressing that specific link. (LLM, conf=0.72)
Experimental — accuracy not yet measured
- Premisecitation
In a Spanish COVID-19 study, psychological inflexibility forecast changes in mental health.
“A Spanish study during the COVID-19 pandemic showed that psychological inflexibility predicted changes in mental health (Hernández-López et al., 2021).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Hernández-López et al., 2021 source
- Premisecitation
Cognitive fusion predicts stress, depression, and anxiety indicators.
“The predictive role of cognitive fusion on psychopathological indicators of stress, depression, and anxiety has been demonstrated in previous studies (Bramwell & Richardson, 2018)”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Bramwell & Richardson, 2018 source
The Results (Bivariate Correlations; page unavailable) report that changes in cognitive fusion correlated with changes in depression and overall distress. The Methods (Statistical Analysis; page unavailable) say the sample was too small for regression, and the Discussion proposes examining individual distress subscales in future work. The paper therefore does not demonstrate that fusion predicts separate stress and anxiety indicators. (LLM, conf=0.88)
Experimental — accuracy not yet measured
- Findingown data
Mental fatigue positively predicted cognitive fusion (β = 0.319, p < 0.001).
“mental fatigue significantly and positively predicted psychological inflexibility (β = 0.244, p < 0.001), cognitive fusion (β = 0.319, p < 0.001) and negative emotions (β = 0.157, p < 0.01).”
Quote in the paperSubstantial claim - Findingown data
Psychological inflexibility acted as a mediator linking mental fatigue to negative emotions.
“statistically significant mediating effects of psychological inflexibility and cognitive fusion between mental fatigue on nurses' negative emotions”
- Also stated in: § Chain mediation effect test · plain
“psychological inflexibility and cognitive fusion can be seen to play a significant mediating role between nurses' mental fatigue and negative emotions, respectively”
Quote in the paperSubstantial claim- Rests on an assumption: The variables in the mediation model are causally ordered as mental fatigue → psychological inflexibility → cognitive fusion → negative emotions.
- Also stated in: § Chain mediation effect test · plain
- Findingown data
Among the surveyed medical staff, 32.3% experienced stress.
“The results indicated that 27.7% of the medical staff experienced depression, and 32.3% of them feel stressed.”
Quote in the paperNot a substantial claim - Findingown data
Cognitive fusion acted as a mediator linking mental fatigue to negative emotions.
“statistically significant mediating effects of psychological inflexibility and cognitive fusion between mental fatigue on nurses' negative emotions”
- Also stated in: § Chain mediation effect test · plain
“psychological inflexibility and cognitive fusion can be seen to play a significant mediating role between nurses' mental fatigue and negative emotions, respectively”
Quote in the paperSubstantial claim- Rests on an assumption: The variables in the mediation model are causally ordered as mental fatigue → psychological inflexibility → cognitive fusion → negative emotions.
- Also stated in: § Chain mediation effect test · plain
- Findingown data
Psychological inflexibility positively predicted negative emotions (β = 0.152, p < 0.01).
“psychological inflexibility significantly predicted cognitive fusion (β = 0.389, p < 0.001) and negative emotions (β = 0.152, p < 0.01) positively”
Quote in the paperSubstantial claim - Findingown data
Cognitive fusion positively predicted negative emotions (β = 0.559, p < 0.001).
“cognitive fusion significantly predicted negative emotions positively (β = 0.559, p < 0.001).”
Quote in the paperSubstantial claim - Findingown data
Mental fatigue positively predicted negative emotions (β = 0.157, p < 0.01).
“mental fatigue significantly and positively predicted psychological inflexibility (β = 0.244, p < 0.001), cognitive fusion (β = 0.319, p < 0.001) and negative emotions (β = 0.157, p < 0.01).”
Quote in the paperSubstantial claim - Findingown data
Psychological inflexibility positively predicted cognitive fusion (β = 0.389, p < 0.001).
“psychological inflexibility significantly predicted cognitive fusion (β = 0.389, p < 0.001) and negative emotions (β = 0.152, p < 0.01) positively”
Quote in the paperSubstantial claim - Findingown data
Mental fatigue positively predicted psychological inflexibility (β = 0.244, p < 0.001).
“mental fatigue significantly and positively predicted psychological inflexibility (β = 0.244, p < 0.001), cognitive fusion (β = 0.319, p < 0.001) and negative emotions (β = 0.157, p < 0.01).”
Quote in the paperSubstantial claim - Findingown data
Among the surveyed medical staff, 27.7% experienced depression.
“The results indicated that 27.7% of the medical staff experienced depression, and 32.3% of them feel stressed.”
Quote in the paperNot a substantial claim - Findingown data
Psychological inflexibility and cognitive fusion together serially mediated the link from mental fatigue to negative emotions.
“statistically, significant chain mediating effects of psychological inflexibility and cognitive fusion.”
- Also stated in: § Chain mediation effect test · plain
“psychological inflexibility and cognitive fusion play a chain mediating role”
Quote in the paperSubstantial claim- Rests on an assumption: The variables in the mediation model are causally ordered as mental fatigue → psychological inflexibility → cognitive fusion → negative emotions.
- Also stated in: § Chain mediation effect test · plain
- Findingown data
The 95% confidence intervals for the three mediation pathways were statistically significant.
“The 95% confidence intervals for the three pathways were statistically significant.”
Quote in the paperSubstantial claim- Rests on an assumption: The variables in the mediation model are causally ordered as mental fatigue → psychological inflexibility → cognitive fusion → negative emotions.
- Premisecitation
Nurses with greater fatigue report stronger negative emotions, including depression, anxiety, and stress.
“Those nurses who feel higher levels of fatigue likewise experience more intense negative emotions such as depression, anxiety, and stress (Mitchell et al., 2021).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Mitchell et al., 2021 source
- Study design and conductreasoning
Because the design was cross-sectional, causal links among the variables cannot be established.
“this study was a cross-sectional design, and the causal relationship between the variables could not be determined.”
Quote in the paperSubstantial claim - Premisecitation
Executive function strongly shapes psychological inflexibility.
“Previous studies have shown that executive function is a major influence on psychological inflexibility”
Quote in the paperSubstantial claim0 of 1 sources checked- cites van der Linden et al., 2003 source
- Study design and conductown data
The study lacked data on how many nurses had contact with COVID patients or worked in COVID-related units.
“we did not collect data about the proportion of nurses contacted with COVID patients or worked on COVID-related departments clearly”
Quote in the paperNot a substantial claim - Premisecitation
Psychological inflexibility has a significant effect on negative emotions like anxiety and depression.
“psychological inflexibility significantly affects negative emotions such as anxiety and depression, leading to a range of psychological problems such as emotional distress, post-traumatic stress disorder (PTSD), and burnout (Fidao et al., 2021).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Fidao et al., 2021 source
- Premisecitation
During COVID-19, more than a quarter of nurses had anxiety, depression, or stress.
“the prevalence of anxiety, depression, and stress among nurses during COVID-19 exceeded 25%”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Sun et al., 2021 source
- Interpretationown data
Mental fatigue causes higher negative emotions among nurses.
“We found that a high level of mental fatigue caused a high level of negative emotions.”
Quote in the paperSubstantial claim- Rests on an assumption: The variables in the mediation model are causally ordered as mental fatigue → psychological inflexibility → cognitive fusion → negative emotions.
- Rests on an assumption: The sample of nurses in Beijing is representative of nurses during the COVID-19 pandemic.
- Interpretationnone given
The negative effects of mental fatigue arise from impaired cognitive functioning.
“the negative effects of mental fatigue come from impairment of cognitive functioning”
Quote in the paperSubstantial claim- Rests on an assumption: The variables in the mediation model are causally ordered as mental fatigue → psychological inflexibility → cognitive fusion → negative emotions.
- Premisecitation
Difficulty regulating emotions can lead to more negative emotions.
“impairment of emotion regulation may be the culprit in bringing on more negative emotions (Plass & Kalyuga, 2019).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Plass & Kalyuga, 2019 source
- Interpretationreasoning
Mental fatigue worsens emotion regulation by raising cognitive load.
“So mental fatigue impairs emotion regulation as increasing cognitive load.”
Quote in the paperSubstantial claim
- Classified as probably not a substantial claim. 5
- May combine two claims. 12
- The quote only partly states this claim. 1
Classified as probably not a substantial claim. May combine two claims.
PremisecitationPsychological inflexibility and cognitive fusion are core components of acceptance and commitment therapy.
“psychological inflexibility (PI) is one of the core concepts of ACT”
- Also stated in: § The chain mediating role of psychological inflexibility and cognitive fusion · plain
“ACT considers cognitive fusion as a key feature of psychological inflexibility”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Hayes et al., 2006 source
- Also stated in: § The chain mediating role of psychological inflexibility and cognitive fusion · plain
May combine two claims.
PremisecitationMental fatigue lowers cognitive control and makes cognitive fusion more likely.
“mental fatigue leads to reduced cognitive control and is more likely to trigger cognitive fusion (Bramwell & Richardson, 2018).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Bramwell & Richardson, 2018 source
The Discussion reports that reductions in cognitive fusion were associated with improvements in distress and depression, but it does not address mental fatigue or cognitive control. Searches for mental fatigue, reduced cognitive control, and related terms found no passage supporting the claimed sequence. (LLM, conf=0.72)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationMental fatigue harms emotion regulation but leaves emotion reactivity unchanged.
“mental fatigue impairs emotion regulation without affecting emotion reactivity, (Grillon et al., 2015).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Grillon et al., 2015 source
May combine two claims.
Findingown dataNegative emotions, cognitive fusion, psychological inflexibility, and mental fatigue were all positively correlated with one another.
“correlation analyses showed significant positive pairwise correlations between mental fatigue, psychological inflexibility, cognitive fusion, and negative emotions among nurses.”
- Also stated in: § Correlations between all variables · plain
“psychological inflexibility, mental fatigue, and cognitive fusion were all significantly and positively correlated with negative emotions, and all three variables were significantly and positively correlated with each other in two ways.”
Quote in the paperSubstantial claim- Also stated in: § Correlations between all variables · plain
May combine two claims.
Findingown dataThe indirect effect through cognitive fusion was 0.178, accounting for 66.41% of the total effect.
“(2) indirect effect 2 (0.178, 66.41% of the total effect): Mental Fatigue → cognitive fusion → negative emotions”
Quote in the paperSubstantial claim- Rests on an assumption: The variables in the mediation model are causally ordered as mental fatigue → psychological inflexibility → cognitive fusion → negative emotions.
May combine two claims.
Findingown dataThe indirect effect through psychological inflexibility was 0.037, accounting for 13.85% of the total effect.
“(1) indirect effect 1 (0.037, 13.85% of the total effect): mental fatigue → psychological inflexibility → negative emotions”
Quote in the paperSubstantial claim- Rests on an assumption: The variables in the mediation model are causally ordered as mental fatigue → psychological inflexibility → cognitive fusion → negative emotions.
May combine two claims.
Findingown dataThe indirect effect through psychological inflexibility and cognitive fusion in sequence was 0.05, accounting for 19.74% of the total effect.
“(3) indirect effect 3 ( 0.05, accounting for 19.74% of the total effect): mental fatigue → psychological inflexibility → cognitive fusion → negative emotions”
Quote in the paperSubstantial claim- Rests on an assumption: The variables in the mediation model are causally ordered as mental fatigue → psychological inflexibility → cognitive fusion → negative emotions.
May combine two claims.
Study design and conductown dataHarman's single-factor test showed no common method bias; the first factor accounted for 27.78%, under the 40% cutoff.
“the variance explained by the first common factor was 27.78%, which was less than the critical criterion of 40%, indicating that there was no common method bias in this study.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
PremisecitationPsychological inflexibility and cognitive fusion forecast negative emotions.
“Psychological inflexibility and cognitive fusion, as important diagnostic criteria for mental health, predict negative emotions (Xing et al., 2020).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Xing et al., 2020 source
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoningThe pre-study sample size calculation called for a minimum of 384 valid questionnaires.
“at least 384 valid questionnaires need to be obtained.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationMental fatigue, psychological inflexibility, and cognitive fusion each affect negative emotions and are intercorrelated.
“mental fatigue, psychological inflexibility, and cognitive fusion all have an impact on negative emotions, and these three factors are correlated with each other.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationMental fatigue damages executive functions, which lowers psychological flexibility.
“mental fatigue makes individuals' executive functions impaired, leading to an inability to continuously focus on situational needs and thus to match and adopt optimal strategies, resulting in significantly reduced psychological flexibility (Jacquet et al., 2021).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Jacquet et al., 2021 source
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenResponses from self-report questionnaires could have been influenced by social desirability bias.
“results obtained from the self-report questionnaire may have been subject to social desirability bias.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationCognitive resources are finite, and regulating emotions demands effortful cognitive control.
“Cognitive Load Theory suggests that individual cognitive resources are limited, and emotion regulation requires effortful cognitive control (Sweller et al., 1994).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Sweller et al., 1994
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
The quote only partly states this claim.
Study design and conductown dataIn this sample, the instruments showed acceptable internal consistency, with Cronbach's alphas between 0.791 and 0.970.
“The Cronbach alpha coefficient in this study was 0.791.”
- Also stated in: § Data gathering instrument · plain
“The Cronbach alpha coefficient in this study was 0.970.”
- Also stated in: § Data gathering instrument · plain
“The Cronbach alpha coefficient in this study was 0.965.”
Quote in the paperNot a substantial claim- Also stated in: § Data gathering instrument · plain
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataAfter exclusions, 419 valid questionnaires remained, yielding an effective response rate of 81.4%.
“419 valid questionnaires were left after deleting the questionnaires with too many missing items (i.e., more than 20% of items were not answered) or too short answer time (i.e., the questionnaire completion time was less than 1 min), with an effective response rate of 81.4% eventually.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
The variables in the mediation model are causally ordered as mental fatigue → psychological inflexibility → cognitive fusion → negative emotions.
“We proposed a conceptual model (Fig. 1)”
“mental fatigue → psychological inflexibility → cognitive fusion → negative emotions”
The paper relies on this without support.
The sample of nurses in Beijing is representative of nurses during the COVID-19 pandemic.
“An online survey was conducted in Beijing, China, in August 2020.”
“survey 419 nurses in Beijing”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Reported age spread is incompatible with the stated age range
MajorIf all 419 participants were aged 17-28 and their mean age was 27.99, their standard deviation could not exceed about 0.33 years. The reported standard deviation is 6.1 years.
“The study was conducted in August 2020, which included 419 medical staff between 17 to 28 years.”
“The mean age of our respondents was 27.99 years (SD = 6.1 years).”
Indirect-effect shares leave no room for the reported direct effect
MinorThe three indirect pathways are assigned shares of 13.85%, 66.41%, and 19.74% of the total effect, which add to 100%. That contradicts the separately reported nonzero direct effect of mental fatigue on negative emotions.
“(1) indirect effect 1 (0.037, 13.85% of the total effect): mental fatigue → psychological inflexibility → negative emotions; (2) indirect effect 2 (0.178, 66.41% of the total effect): Mental Fatigue → cognitive fusion → negative emotions; (3) indirect effect 3 ( 0.05, accounting for 19.74% of the total effect)”
“mental fatigue significantly and positively predicted psychological inflexibility (β = 0.244, p < 0.001), cognitive fusion (β = 0.319, p < 0.001) and negative emotions (β = 0.157, p < 0.01).”
One mediation statement reverses the modeled pathway
MinorOne results statement describes mental fatigue as a mediator of psychological inflexibility's effect. The listed pathway instead places psychological inflexibility between mental fatigue and negative emotions.
“The results of the mediation analysis (see Fig. 2) indicated that mental fatigue and cognitive fusion played a mediating role in the effect of psychological inflexibility on negative emotions.”
“mental fatigue → psychological inflexibility → negative emotions”
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“, they devote more attention and processing to negative information and will be more inclined to identify with negative information (Jenness et al., 2021).”
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Manager Support for Wellness Champions: A Case Study for Consideration and Practice Implications
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“Those nurses who feel higher levels of fatigue likewise experience more intense negative emotions such as depression, anxiety, and stress (Mitchell et al., 2021).”
Cabrera, I., Márquez-González, M., Gallego-Alberto, L., Pedroso-Chaparro, M. D. S., Barrera-Caballero, S., & Losada, A. (2022) · Aging & Mental Health · doi:10.1080/13607863.2021.1871883 · Cited by 9 · see citing works
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FatigueSense: Multi-Device and Multimodal Wearable Sensing for Detecting Mental Fatigue
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Gil‐Almagro, F., Monge, F. J. C., García-Hedrera, F. J., & Peñacoba, C. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13123498 · Cited by 9 · see citing works
“Throughout the COVID-19 pandemic, cognitive fusion, characterized as an over-identification with thoughts and an inability to distract oneself from them, has been found to be a clear precipitator of negative psychoemotional consequences on HCWs [41].”
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“While pandemic-related fatigue among nurses has been extensively studied, the specific topic of PPE-related stress during the pandemic remains relatively unexplored [34–36].”
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“SR can keep nurses once hired, maintain their confidence and performance, and safeguard them from MF [20].”
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“In a previous study, nurses experiencing mental fatigue exhibited heightened psychological inflexibility [13].”
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“In healthcare personnel, cognitive fusion has been shown to be a clear negative factor associated with increased mental fatigue [36].”
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“Interventions using acceptance and commitment therapy for mental fatigue and negative emotions are more effective [40].”
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Gil‐Almagro, F., García-Hedrera, F. J., Peñacoba, C., & Monge, F. J. C. (2024) · Medicina · doi:10.3390/medicina60081230 · Cited by 4 · see citing works
“Studies on HCWs during the pandemic have found a negative effect of thought rumination on anxiety [36,69].”
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“Employees often need to work longer hours, complete more tasks, be more flexible, and tolerate continuous environmental changes, which can easily bring more work pressure on employees (Wang et al., 2022a, b).”
Fatigue estimation of OOWs based on eye-tracking technology: A hybrid experimental study
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“Nurses’ fatigue could cause various physical symptoms and negative emotions, further affecting their health and work performance [9].”
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“More than half of the participants reported they experienced no negative emotions during the COVID-19 pandemic, which was contrary to the reports of Wang et al. and Li et al. [26, 27].”
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Walking Beyond Crisis: Kerala Women’s Psychological Health During the Pandemic Era
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“…in HCWs is a topic of special interest in health promotion, highlighting the impact of certain psychological variables (as protective or risk factors) on the mental health of healthcare personnel during the COVID-19 pandemic, including traits such as cognitive fusion [20] or hardiness [21].”
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“Nurses’ fatigue could cause various physical symptoms and negative emotions, further affecting their health and work performance(Wang et al., 2022).”
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Job Insecurity and Insomnia Among Hospitality Employees in Pakistan: A Moderated Mediation StudyPreprint
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Identifying individuals with high susceptibility to mental fatigue: A functional connectivity study
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Finding a Balance Between Being Connected and Well-Being
Nayak, A., Satpathy, I., & Jain, V. K. (2026) · IGI Global eBooks · doi:10.4018/979-8-3373-8307-1.ch016
- Authors
- Wang, D., Xie, X., Tian, H., Wu, T., Liu, C., Huang, K., Gong, R., Yu, Y., Luo, T., Jiao, R., & Zhang, L.
- Affiliations
- Chinese PLA General Hospital (CN)
- Central China Normal University (CN)
- Wuhan Children's Hospital (CN)
- First Affiliated Hospital of Chinese PLA General Hospital (CN)
- Chinese People's Armed Police Force (CN)
- Corresponding author
- Zhang, Lin
- Venue
- Current Psychology
- Published
- 2022-07-15
- Volume
- 41
- Issue
- 11
- Pages
- 8123-8131
- ISSN
- 1046-1310 (ISSN-L)
- 1936-4733
- PMC
- PMC9285871
- OpenAlex
- W4285492634
- Cited by
- 33
- References
- 39
- Citations by year
- 2026: 6 · 2025: 11 · 2024: 9 · 2023: 7
- FWCI
- 6.16
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Current Psychology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- self-determined research funds of CCNU from the colleges’ basic research and operation of MOE (CCNU20TD001)
- Topics
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Health Professions › Occupational Therapy › Occupational Health and Burnout
- Keywords
- mental fatigue, negative emotions, nurses, COVID-19 pandemic, psychological inflexibility, cognitive fusion, depression, anxiety, stress, acceptance and commitment therapy, frontline health workers, mediating effect
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