Review and meta-analysis of couple-oriented interventions for chronic illness
Open accessAbstract
BACKGROUND: Evidence continues to build for the impact of the marital relationship on health as well as the negative impact of illness on the partner. Targeting both patient and partner may enhance the efficacy of psychosocial or behavioral interventions for chronic illness. PURPOSE: The purpose of this report is to present a cross-disease review of the characteristics and findings of studies evaluating couple-oriented interventions for chronic physical illness. METHODS: We conducted a qualitative review of 33 studies and meta-analyses for a subset of 25 studies. RESULTS: Identified studies focused on cancer, arthritis, cardiovascular disease, chronic pain, HIV, and Type 2 diabetes. Couple interventions had significant effects on patient depressive symptoms (d = 0.18, p < 0.01, k = 20), marital functioning (d = 0.17, p < 0.01, k = 18), and pain (d = 0.19, p < 0.01, k = 14) and were more efficacious than either patient psychosocial intervention or usual care. CONCLUSIONS: Couple-oriented interventions have small effects that may be strengthened by targeting partners' influence on patient health behaviors and focusing on couples with high illness-related conflict, low partner support, or low overall marital quality. Directions for future research include assessment of outcomes for both patient and partner, comparison of couple interventions to evidence-based patient interventions, and evaluation of mechanisms of change.
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- Authors
- Martire, L. M., Schulz, R., Helgeson, V. S., Small, B. J., & Saghafi, E. M.
- Affiliations
- Pennsylvania State University (US)
- University of Pittsburgh (US)
- Carnegie Mellon University (US)
- University of South Florida (US)
- Corresponding author
- Martire, Lynn M.
- Venue
- Annals of Behavioral Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-08-10
- Volume
- 40
- Issue
- 3
- Pages
- 325-342
- ISSN
- 0742-5554 (ISSN-L)
- 0883-6612
- 1532-4796
- PMC
- PMC4101802
- OpenAlex
- W2013987273
- Cited by
- 419
- References
- 110
- Citations by year
- 2026: 11 · 2025: 26 · 2024: 24 · 2023: 16 · 2022: 29 · 2021: 45 · 2020: 39 · 2019: 23 · 2018: 20 · 2017: 35 · 2016: 32 · 2015: 40 · 2014: 27 · 2013: 18 · 2012: 26
- FWCI
- 2.04
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annals of Behavioral Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (R01AG026010)
- National Institute of Nursing Research (R01NR009573)
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK060586)
- Topics
- Social Sciences › Psychology › Social Psychology › Attachment and Relationship Dynamics
- Health Sciences › Health Professions › Pharmacy › Nursing care and research
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Keywords
- chronic disease, marital relationships, depressive symptoms, marital functioning, pain, cancer, arthritis, cardiovascular disease, chronic pain, HIV, type 2 diabetes, partner support, psychosocial interventions, health behavior
- MeSH terms
- Chronic Disease, Female, Humans, Interpersonal Relations, Male, Marriage, Patient Education as Topic, Self Care, Health Behavior, Treatment Outcome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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