Hyperpalatability and the Generation of Obesity: Roles of Environment, Stress Exposure and Individual Difference
Abstract
Purpose of review This review investigates how exposure to palatable food and its associated cues alters appetite regulation and feeding behaviour to drive overeating and weight gain.Recent findings Both supraphysiological and physiological feeding systems are affected by exposure to palatable foods and its associated cues. Preclinical research, largely using rodents, has demonstrated that palatable food modulates feeding-related neural systems and food-seeking behaviour by recruiting the mesolimbic reward pathway. This is supported by studies in adolescents which have shown that mesolimbic activity in response to palatable food cues and consumption predicts future weight gain. Additionally, stress exposure, environmental factors and individual susceptibility have been shown to modulate the effects of highly palatable foods on behaviour. Further preclinical research using free-choice diets modelling the modern obesogenic environment is needed to identify how palatable foods drive overeating. Moreover, future clinical research would benefit from more appropriate quantification of palatability, making use of rating systems and surveys.
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A background of ELA may potentiate food addiction behaviours in some individuals, especially within the context of an environment rich in highly processed, calorie dense and extremely palatable food.
“A background of ELA may potentiate food addiction behaviours in some individuals, especially within the context of an environment rich in highly processed, calorie dense and extremely palatable food 4, 21, 22.”
From History of early life adversity is associated with increased food addiction and sex-specific alterations in reward network connectivity in obesity (2019) · cites this paper as [21]
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Neuroadaptive processes associated with palatable food intake: present data and future directions
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Role of DOR in neuronal plasticity changes promoted by food-seeking behaviour
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Stress during Adolescence Alters Palatable Food Consumption in a Context-Dependent Manner
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- Authors
- Leigh, S.-J., Lee, F., & Morris, M. J.
- Affiliations
- UNSW Sydney (AU)
- Corresponding author
- Morris, Margaret J.
- Venue
- Current Obesity Reports
- Published
- 2018-02-13
- Volume
- 7
- Issue
- 1
- Pages
- 6-18
- ISSN
- 2162-4968 (ISSN-L)
- OpenAlex
- W2788923242
- Cited by
- 43
- References
- 119
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 4 · 2023: 6 · 2022: 7 · 2021: 8 · 2020: 4 · 2019: 6 · 2018: 3
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Obesity Reports (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Keywords
- obesity, palatable food, appetite regulation, feeding behaviour, overeating, weight gain, mesolimbic reward pathway, food cues, stress exposure, obesogenic environment, individual differences, adolescent weight gain
- MeSH terms
- Animals, Humans, Hyperphagia, Obesity, Personality, Reward, Stress, Psychological
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