Cited by 43Regulation of Appetite and ObesityEating Disorders and BehaviorsNutrition, Health and Food Behavior

Hyperpalatability and the Generation of Obesity: Roles of Environment, Stress Exposure and Individual Difference

Leigh, Sarah-Jane, Lee, Frances, Morris, Margaret J.·2018·Current Obesity Reports

Abstract

Purpose of review This review investigates how exposure to palatable food and its associated cues alters appetite regulation and feeding behaviour to drive overeating and weight gain.Recent findings Both supraphysiological and physiological feeding systems are affected by exposure to palatable foods and its associated cues. Preclinical research, largely using rodents, has demonstrated that palatable food modulates feeding-related neural systems and food-seeking behaviour by recruiting the mesolimbic reward pathway. This is supported by studies in adolescents which have shown that mesolimbic activity in response to palatable food cues and consumption predicts future weight gain. Additionally, stress exposure, environmental factors and individual susceptibility have been shown to modulate the effects of highly palatable foods on behaviour. Further preclinical research using free-choice diets modelling the modern obesogenic environment is needed to identify how palatable foods drive overeating. Moreover, future clinical research would benefit from more appropriate quantification of palatability, making use of rating systems and surveys.

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Crossref · 10.1007/s13679-018-0292-0

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119 of 119 references verified0 citation errors · 0 not checkable

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Authors
Leigh, S.-J., Lee, F., & Morris, M. J.
Affiliations
UNSW Sydney (AU)
Corresponding author
Morris, Margaret J.
Venue
Current Obesity Reports
Published
2018-02-13
Volume
7
Issue
1
Pages
6-18
ISSN
2162-4968 (ISSN-L)
OpenAlex
W2788923242
Cited by
43
References
119
Citations by year
2026: 2 · 2025: 3 · 2024: 4 · 2023: 6 · 2022: 7 · 2021: 8 · 2020: 4 · 2019: 6 · 2018: 3
FWCI
0.73
Type
journal article
Language
en
Open access
closed
Locations
  • Current Obesity Reports (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
  • Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
  • Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
Keywords
obesity, palatable food, appetite regulation, feeding behaviour, overeating, weight gain, mesolimbic reward pathway, food cues, stress exposure, obesogenic environment, individual differences, adolescent weight gain
MeSH terms
Animals, Humans, Hyperphagia, Obesity, Personality, Reward, Stress, Psychological

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