Role of 5-HT in stress, anxiety, and depression

Role of the amygdala and periaqueductal gray in anxiety and panic.

Graeff, F. G., Silveira, M. C. L., Nogueira, R. L., Audi, E. A., & Oliveira, R. M. W. (1993) · Behavioural Brain Research · doi:10.1016/0166-4328(93)90097-a · Cited by 301 · see citing works

Corticosterone enhances long-term retention in one-day-old chicks trained in a weak passive avoidance learning paradigm

Sandi, C., & Rose, S. P. R. (1994) · Brain Research · doi:10.1016/0006-8993(94)91404-4 · Cited by 234 · see citing works

A two-dimensional neuropsychology of defense: fear/anxiety and defensive distance

McNaughton, N., & Corr, P. J. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.03.005 · Cited by 1,308 · see citing works

Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus

Amat, J., Baratta, M. V., Paul, E., Bland, S. T., Watkins, L. R., & Maier, S. F. (2005) · Nature Neuroscience · doi:10.1038/nn1399 · Cited by 931 · see citing works

Learned helplessness at fifty: Insights from neuroscience.

Maier, S. F., & Seligman, M. E. P. (2016) · Psychological Review · doi:10.1037/rev0000033 · Cited by 919 · see citing works

Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor.

Maier, S. F., & Watkins, L. R. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.021 · Cited by 737 · see citing works

The reinterpretation of dreams: An evolutionary hypothesis of the function of dreaming

Revonsuo, A. (2000) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00004015 · Cited by 676 · see citing works

Serotoninergic regulation of emotional and behavioural control processes

Cools, R., Roberts, A. C., & Robbins, T. W. (2008) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2007.10.011 · Cited by 656 · see citing works

Neurobiology of anorexia and bulimia nervosa

Kaye, W. (2008) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.11.037 · Cited by 625 · see citing works

Opponency revisited: competition and cooperation between dopamine and serotonin

Boureau, Y.-L., & Dayan, P. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.151 · Cited by 456 · see citing works

IDO and interferon-α-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity

Wichers, M. C., Koek, G. H., Robaeys, G., Verkerk, R., Scharpé, S., & Maes, M. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001600 · Cited by 445 · see citing works

Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers

Harmer, C. J., Bhagwagar, Z., Perrett, D. I., Völlm, B. A., Cowen, P. J., & Goodwin, G. M. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300004 · Cited by 420 · see citing works

Exercise Benefits Brain Function: The Monoamine Connection

Lin, T.-W., & Kuo, Y.-M. (2013) · Brain Sciences · doi:10.3390/brainsci3010039 · Cited by 392 · see citing works

Sex differences in anxiety and emotional behavior

Donner, N. C., & Lowry, C. A. (2013) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-013-1271-7 · Cited by 379 · see citing works

Functional subsets of serotonergic neurones: implications for control of the hypothalamic-pituitary-adrenal axis

Lowry, C. A. (2002) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2002.00861.x · Cited by 362 · see citing works

Antidepressant‐like effects of cannabidiol in mice: possible involvement of 5‐HT_1Areceptors

Zanelati, T., Biojone, C., Moreira, F., Guimarães, F., & Joca, S. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00521.x · Cited by 366 · see citing works

MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity

Issler, O., Haramati, S., Paul, E. D., Maeno, H., Navon, I., Zwang, R., Gil, S., Mayberg, H. S., Dunlop, B. W., Menke, A., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.05.042 · Cited by 318 · see citing works

Serotonin Modulates Sensitivity to Reward and Negative Feedback in a Probabilistic Reversal Learning Task in Rats

Bari, A., Theobald, D. E., Caprioli, D., Mar, A. C., Aidoo-Micah, A., Dalley, J. W., & Robbins, T. W. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.233 · Cited by 325 · see citing works

Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects

Duric, V., Banasr, M., Stockmeier, C. A., Simen, A. A., Newton, S. S., Overholser, J. C., Jurjus, G. J., Dieter, L., & Duman, R. S. (2013) · International Journal of Neuropsychopharmacology · doi:10.1017/s1461145712000016 · Cited by 304 · see citing works

The bovine protein α-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress

Markus, C. R., Olivier, B., Panhuysen, G. E., Van der Gugten, J., Alles, M. S., Tuiten, A., Westenberg, H. G., Fekkes, D., Koppeschaar, H. F., & de Haan, E. E. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.6.1536 · Cited by 296 · see citing works

Serotonin, the periaqueductal gray and panic

Graeff, F. G. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2003.12.004 · Cited by 285 · see citing works

Hyporeactivity of ventral striatum towards incentive stimuli in unmedicated depressed patients normalizes after treatment with escitalopram

Stoy, M., Schlagenhauf, F., Sterzer, P., Bermpohl, F., Hägele, C., Suchotzki, K., Schmack, K., Wrase, J., Ricken, R., Knutson, B., et al. (2012) · Journal of Psychopharmacology · doi:10.1177/0269881111416686 · Cited by 279 · see citing works

Behavioural and neurochemical effects induced by chronic mild stress applied to two different rat strains

Bekris, S., Antoniou, K., Daskas, S., & Papadopoulou-Daifoti, Z. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.01.005 · Cited by 281 · see citing works

5‐HT_1Areceptors are involved in the cannabidiol‐induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats

Resstel, L. B. M., Tavares, R. F., Lisboa, S. F. S., Joca, S. R. L., Corrêa, F. M. A., & Guimarães, F. S. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2008.00046.x · Cited by 283 · see citing works

Serotonin, inhibition, and negative mood

Dayan, P., & Huys, Q. J. M. (2008) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0040004 · Cited by 263 · see citing works

Raphe serotonin neurons are not homogenous: Electrophysiological, morphological and neurochemical evidence

Calizo, L. H., Akanwa, A., Ma, X., Pan, Y.-Z., Lemos, J. C., Craige, C., Heemstra, L. A., & Beck, S. G. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.04.008 · Cited by 252 · see citing works

Previous Experience with Behavioral Control over Stress Blocks the Behavioral and Dorsal Raphe Nucleus Activating Effects of Later Uncontrollable Stress: Role of the Ventral Medial Prefrontal Cortex

Amat, J., Paul, E., Zarza, C., Watkins, L. R., & Maier, S. F. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.3630-06.2006 · Cited by 249 · see citing works

Corticotropin-Releasing Factor Increases<i>In Vitro</i>Firing Rates of Serotonergic Neurons in the Rat Dorsal Raphe Nucleus: Evidence for Activation of a Topographically Organized Mesolimbocortical Serotonergic System

Lowry, C. A., Rodda, J. E., Lightman, S. L., & Ingram, C. D. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-20-07728.2000 · Cited by 211 · see citing works

Influence of light at night on murine anxiety- and depressive-like responses

Fonken, L. K., Finy, M. S., Walton, J. C., Weil, Z. M., Workman, J. L., Ross, J., & Nelson, R. J. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.07.001 · Cited by 209 · see citing works

The dorsal raphe nucleus and serotonin: implications for neuroplasticity linked to major depression and Alzheimer's disease

MICHELSEN, K., PRICKAERTS, J., & STEINBUSCH, H. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00912-6 · Cited by 196 · see citing works

Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior

Lowry, C. A., Hollis, J. H., de Vries, A., Pan, B., Brunet, L. R., Hunt, J. R. F., Paton, J. F. R., van Kampen, E., Knight, D. M., Evans, A. K., et al. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.01.067 · Cited by 199 · see citing works

Acute tryptophan depletion in healthy volunteers enhances punishment prediction but does not affect reward prediction

Cools, R., Robinson, O. J., & Sahakian, B. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301598 · Cited by 172 · see citing works

Overcoming the effects of stress on synaptic plasticity in the intact hippocampus: rapid actions of serotonergic and antidepressant agents

Shakesby, A. C., Anwyl, R., & Rowan, M. J. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-09-03638.2002 · Cited by 173 · see citing works

Serotonin-1A receptor alterations in depression: a meta-analysis of molecular imaging studies

Wang, L., Zhou, C., Zhu, D., Wang, X., Fang, L., Zhong, J., Mao, Q., Sun, L., Gong, X., Xia, J., et al. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-1025-0 · Cited by 162 · see citing works

Antidepressant‐like effect induced by systemic and intra‐hippocampal administration of DNA methylation inhibitors

Sales, A. J., Biojone, C., Terceti, M. S., Guimarães, F. S., Gomes, M. V., & Joca, S. R. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01489.x · Cited by 147 · see citing works

Collateralized dorsal raphe nucleus projections: A mechanism for the integration of diverse functions during stress

Waselus, M., Valentino, R. J., & Van Bockstaele, E. J. (2011) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2011.05.011 · Cited by 142 · see citing works

A review of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy

Sessa, B., Higbed, L., & Nutt, D. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00138 · Cited by 141 · see citing works

Effects of dopaminergic and serotonergic manipulation on emotional processing: A pharmacological fMRI study

Takahashi, H., Yahata, N., Koeda, M., Takano, A., Asai, K., Suhara, T., & Okubo, Y. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.05.039 · Cited by 114 · see citing works

The response of neurons in the bed nucleus of the stria terminalis to serotonin: Implications for anxiety

Hammack, S. E., Guo, J.-D., Hazra, R., Dabrowska, J., Myers, K. M., & Rainnie, D. G. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.05.013 · Cited by 103 · see citing works

MDMA and PTSD treatment

Sessa, B. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2016.07.004 · Cited by 97 · see citing works

Effects of Rhodiola rosea L. extract on behavioural and physiological alterations induced by chronic mild stress in female rats

Mattioli, L., Funari, C., & Perfumi, M. (2009) · Journal of Psychopharmacology · doi:10.1177/0269881108089872 · Cited by 91 · see citing works

Neuropathic pain and the endocannabinoid system in the dorsal raphe: pharmacological treatment and interactions with the serotonergic system

Palazzo, E., De Novellis, V., Petrosino, S., Marabese, I., Vita, D., Giordano, C., Di Marzo, V., Mangoni, G. S., Rossi, F., & Maione, S. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05086.x · Cited by 86 · see citing works

Learning from negative feedback in patients with major depressive disorder is attenuated by SSRI antidepressants

Herzallah, M. M., Moustafa, A. A., Natsheh, J. Y., Abdellatif, S. M., Taha, M. B., Tayem, Y. I., Sehwail, M. A., Amleh, I., Petrides, G., Myers, C. E., et al. (2013) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2013.00067 · Cited by 77 · see citing works

Effects of<i>TPH2</i>gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders

Spagnolo, P. A., Norato, G., Maurer, C. W., Goldman, D., Hodgkinson, C., Horovitz, S., & Hallett, M. (2020) · Journal of Neurology, Neurosurgery &amp; Psychiatry · doi:10.1136/jnnp-2019-322636 · Cited by 62 · see citing works

The effects of drugs on human models of emotional processing: an account of antidepressant drug treatment

Pringle, A., & Harmer, C. J. (2015) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2015.17.4/apringle · Cited by 61 · see citing works

5-hydroxytryptamine 2C receptors in the dorsal striatum mediate stress-induced interference with negatively reinforced instrumental escape behavior

Strong, P. V., Christianson, J. P., Loughridge, A. B., Amat, J., Maier, S. F., Fleshner, M., & Greenwood, B. N. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.09.041 · Cited by 61 · see citing works

Lesion of the bed nucleus of the stria terminalis enhances learned despair

Schulz, D., & Canbeyli, R. S. (2000) · Brain Research Bulletin · doi:10.1016/s0361-9230(00)00235-5 · Cited by 57 · see citing works

Effect of the serotonin antagonists ritanserin and ketanserin in Cushing’s disease

Sonino, N., Fava, G. A., Fallo, F., Franceschetto, A., Belluardo, P., & Boscaro, M. (2000) · Pituitary · doi:10.1023/a:1009986822146 · Cited by 41 · see citing works

5-HT6R null mutatrion induces synaptic and cognitive defects

Sun, Z., Wang, B., Chen, C., Li, C., & Zhang, Y. (2021) · Aging Cell · doi:10.1111/acel.13369 · Cited by 35 · see citing works

Role of dopaminergic and serotonergic systems on behavioral stimulatory effects of low-dose alprazolam and lorazepam

Bentué-Ferrer, D., Reymann, J. M., Tribut, O., Allain, H., Vasar, E., & Bourin, M. (2001) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(00)00137-1 · Cited by 30 · see citing works

Serotonergic neuromodulation of synaptic plasticity

Higa, G. S. V., Viana, F. J. C., Francis-Oliveira, J., Cruvinel, E., Franchin, T. S., Marcourakis, T., Ulrich, H., & De Pasquale, R. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.110036 · Cited by 29 · see citing works

Long-lasting marked inhibition of periaqueductal gray-evoked defensive behaviors in inescapably-shocked rats

Quintino‐dos‐Santos, J. W., Müller, C. J. T., C. Santos, A. M., Tufik, S., Rosa, C. A., & Schenberg, L. C. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12410 · Cited by 7 · see citing works