Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

Mello, C. C., Kramer, J. M., Stinchcomb, D. T., & Ambros, V. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb04966.x · Cited by 3,095

Regulating the fate of mRNA: the control of cellular iron metabolism

Klausner, R. D., Rouault, T. A., & Harford, J. B. (1993) · Cell · doi:10.1016/0092-8674(93)90046-s · Cited by 1,210

Heterochronic Mutants of the Nematode Caenorhabditis elegans

Ambros, V., & Horvitz, H. R. (1984) · Science · doi:10.1126/science.6494891 · Cited by 797

RNA Structure Prediction

Turner, D. H., Sugimoto, N., & Freier, S. M. (1988) · Annual Review of Biophysics and Biophysical Chemistry · doi:10.1146/annurev.bb.17.060188.001123 · Cited by 647

A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans

Fire, A. Z., Harrison, S. M. W., & Dixon, D. (1990) · Gene · doi:10.1016/0378-1119(90)90224-f · Cited by 603

The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation

Sachs, A. B., & Davis, R. W. (1989) · Cell · doi:10.1016/0092-8674(89)90938-0 · Cited by 552

Mutations that lead to reiterations in the cell lineages of C. elegans.

Chalfie, M., Horvitz, H., & Sulston, J. (1981) · Cell · doi:10.1016/0092-8674(81)90501-8 · Cited by 541

RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos

Wharton, R. P., & Struhl, G. (1991) · Cell · doi:10.1016/0092-8674(91)90368-9 · Cited by 386

A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans

Ambros, V. (1989) · Cell · doi:10.1016/0092-8674(89)90171-2 · Cited by 361

microRNAs in Cardiovascular Diseases

Condorelli, G., Latronico, M. V. G., & Cavarretta, E. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.01.050 · Cited by 385

Distance constraints between microRNA target sites dictate efficacy and cooperativity

Sætrom, P., Heale, B. S. E., Snøve, O., Aagaard, L., Alluin, J. V., & Rossi, J. J. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm133 · Cited by 400

MiR-210 – micromanager of the hypoxia pathway

Huang, X., Le, Q., & Giaccia, A. J. (2010) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2010.03.004 · Cited by 376

AN ABUNDANCE OF RNA REGULATORS

Storz, G., Altuvia, S., & Wassarman, K. M. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.082803.133136 · Cited by 370

MicroRNAs: novel regulators in cardiac development and disease

Thum, T., Catalucci, D., & Bauersachs, J. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn137 · Cited by 377

How does Lin28 let-7 control development and disease?

Thornton, J. E., & Gregory, R. I. (2012) · Trends in Cell Biology · doi:10.1016/j.tcb.2012.06.001 · Cited by 374

A biochemical approach to identifying microRNA targets

Karginov, F. V., Conaco, C., Xuan, Z., Schmidt, B. H., Parker, J. S., Mandel, G., & Hannon, G. J. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709971104 · Cited by 371

Phosphorylation of the Human MicroRNA-Generating Complex Mediates MAPK/Erk Signaling

Paroo, Z., Ye, X., Chen, S., & Liu, Q. (2009) · Cell · doi:10.1016/j.cell.2009.06.044 · Cited by 380

MicroRNAs prevent precocious gene expression and enable pattern formation during plant embryogenesisPreprint

Nodine, M. D., & Bartel, D. P. (2010) · Genes & Development · doi:10.1101/gad.1986710 · Cited by 360

An Emerging Role for Epigenetic Dysregulation in Arsenic Toxicity and Carcinogenesis

Ren, X., McHale, C. M., Skibola, C. F., Smith, A. H., Smith, M. T., & Zhang, L. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.1002114 · Cited by 364

MicroRNAs in vertebrate development

Harfe, B. D. (2005) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2005.06.012 · Cited by 357

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

Landthaler, M., Gaidatzis, D., Rothballer, A., Chen, P., Soll, S. J., Dinic, L., Ojo, T., Hafner, M., Zavolan, M., & Tuschl, T. (2008) · RNA · doi:10.1261/rna.1351608 · Cited by 370

Glimpses of a Tiny RNA World

Ruvkun, G. (2001) · Science · doi:10.1126/science.1066315 · Cited by 357

Mammalian microRNAs: a small world for fine-tuning gene expression

Sevignani, C., Calin, G. A., Siracusa, L. D., & Croce, C. M. (2006) · Mammalian Genome · doi:10.1007/s00335-005-0066-3 · Cited by 362

MicroRNAs in colorectal cancer: translation of molecular biology into clinical application

Slabý, O., Svoboda, M., Michálek, J., & Vyzula, R. (2009) · Molecular Cancer · doi:10.1186/1476-4598-8-102 · Cited by 361

The Caenorhabditis elegans hunchback-like Gene lin-57/hbl-1 Controls Developmental Time and Is Regulated by MicroRNAs

Abrahante, J. E., Daul, A. L., Li, M., Volk, M. L., Tennessen, J. M., Miller, E. A., & Rougvie, A. E. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00127-8 · Cited by 357

The C. elegans hunchback Homolog, hbl-1, Controls Temporal Patterning and Is a Probable MicroRNA Target

Lin, S.-Y., Johnson, S., Abraham, M. C., Vella, M. C., Pasquinelli, A. E., Gamberi, C., Gottlieb, E., & Slack, F. J. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00124-2 · Cited by 346

A microRNA Mediates EGF Receptor Signaling and Promotes Photoreceptor Differentiation in the Drosophila Eye

Li, X., & Carthew, R. W. (2005) · Cell · doi:10.1016/j.cell.2005.10.040 · Cited by 304

MDHGI: Matrix Decomposition and Heterogeneous Graph Inference for miRNA-disease association prediction

Chen, X., Yin, J., Qu, J., & Li, H. (2018) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1006418 · Cited by 349

Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity

Parker, J. S., Roe, S. M., & Barford, D. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600488 · Cited by 350

MicroRNAs as regulators of metabolic disease: pathophysiologic significance and emerging role as biomarkers and therapeutics

Deiuliis, J. A. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.170 · Cited by 365

Redefining MicroRNA Targets

Seitz, H. (2009) · Current Biology · doi:10.1016/j.cub.2009.03.059 · Cited by 359

The microRNA-200 family: small molecules with novel roles in cancer development, progression and therapy

Humphries, B. A., & Yang, C. (2015) · Oncotarget · doi:10.18632/oncotarget.3052 · Cited by 343

MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode

Chang, S. S., Johnston, R. J., Frøkjær‐Jensen, C., Lockery, S. R., & Hobert, O. (2004) · Nature · doi:10.1038/nature02752 · Cited by 349

Control of cell proliferation pathways by microRNAs

Bueno, M. J., de Castro, I. P., & Malumbres, M. (2008) · Cell Cycle · doi:10.4161/cc.7.20.6833 · Cited by 352

MicroRNAs and Cell Cycle Regulation

Carleton, M. O., Cleary, M. A., & Linsley, P. S. (2007) · Cell Cycle · doi:10.4161/cc.6.17.4641 · Cited by 342

The role of microRNAs in cancer: No small matter

Wiemer, E. A. C. (2007) · European Journal of Cancer · doi:10.1016/j.ejca.2007.04.002 · Cited by 348

The Many Faces of RNAi

Ketting, R. F. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.01.012 · Cited by 353

A translational study of circulating cell-free microRNA-1 in acute myocardial infarction

Cheng, Y., Tan, N., Yang, J., Liu, X., Cao, X., He, P., Dong, X., Qin, S., & Zhang, C. (2010) · Clinical Science · doi:10.1042/cs20090645 · Cited by 342

Control of Developmental Timing by MicroRNAs and Their Targets

Pasquinelli, A. E., & Ruvkun, G. (2002) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.18.012502.105832 · Cited by 341

Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation

Hausser, J., Syed, A. P., Bilen, B., & Zavolan, M. (2013) · Genome Research · doi:10.1101/gr.139758.112 · Cited by 317

The Silent Revolution: RNA Interference as Basic Biology, Research Tool, and Therapeutic

Dykxhoorn, D. M., & Lieberman, J. (2004) · Annual Review of Medicine · doi:10.1146/annurev.med.56.082103.104606 · Cited by 341

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

Davis‐Dusenbery, B. N., & Hata, A. (2009) · Cell Communication and Signaling · doi:10.1186/1478-811x-7-18 · Cited by 340

MicroRNA expression profiles predictive of human renal allograft status

Anglicheau, D., Sharma, V. K., Ding, R., Hummel, A., Snopkowski, C., Dadhania, D. M., Seshan, S. V., & Suthanthiran, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813121106 · Cited by 343

MicroRNA-21 in Cardiovascular Disease

Cheng, Y., & Zhang, C. (2010) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-010-9169-7 · Cited by 343

MicroRNA target site polymorphisms and human disease

Sethupathy, P., & Collins, F. S. (2008) · Trends in Genetics · doi:10.1016/j.tig.2008.07.004 · Cited by 333

Life and death in the cytoplasm: messages from the 3′ end

Wickens, M., Anderson, P., & Jackson, R. J. (1997) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(97)80132-3 · Cited by 332

Genome‐wide mapping of the HY5 ‐mediated genenetworks in Arabidopsis that involve both transcriptional and post‐transcriptional regulation

Zhang, H., He, H., Wang, X., Wang, X., Yang, X., Li, L., & Deng, X. W. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04426.x · Cited by 330

Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and Broad-Complex gene activity

Sempere, L. F., Sokol, N. S., Dubrovsky, E. B., Berger, E. M., & Ambros, V. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00208-2 · Cited by 330

ncRNA-Encoded Peptides or Proteins and Cancer

Wang, J., Zhu, S., Meng, N., He, Y., Lu, R., & Yan, G. (2019) · Molecular Therapy · doi:10.1016/j.ymthe.2019.09.001 · Cited by 330

Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites

Moss, E. G., & Tang, L. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00126-x · Cited by 328

MicroRNA-124a Regulates Foxa2 Expression and Intracellular Signaling in Pancreatic β-Cell Lines*

Baroukh, N., Ravier, M. A., Loder, M. K., Hill, E. V., Bounacer, A., Scharfmann, R., Rutter, G. A., & Van Obberghen, E. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611841200 · Cited by 326

Non-coding RNAs and potential therapeutic targeting in cancer

Toden, S., Zumwalt, T. J., & Goel, A. (2020) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2020.188491 · Cited by 335

Regulation of MicroRNA Expression and Abundance during Lymphopoiesis

Kuchen, S., Resch, W., Yamane, A., Kuo, N., Li, Z., Chakraborty, T., Wei, L., Laurence, A. D. J., Yasuda, T., Peng, S., et al. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.009 · Cited by 324

Therapeutic Oligonucleotides: State of the Art

Smith, C. I. E., & Zain, R. (2018) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010818-021050 · Cited by 338

Integrative approaches for predicting microRNA function and prioritizing disease-related microRNA using biological interaction networks

Zeng, X., Zhang, X., & Zou, Q. (2015) · Briefings in Bioinformatics · doi:10.1093/bib/bbv033 · Cited by 325

Antisense-Mediated Depletion Reveals Essential and Specific Functions of MicroRNAs in Drosophila Development

Leaman, D. P., Chen, P., Fak, J. J., Yalçın, A., Pearce, M., Unnerstall, U., Marks, D. S., Sander, C., Tuschl, T., & Gaul, U. (2005) · Cell · doi:10.1016/j.cell.2005.04.016 · Cited by 325

Antisense RNA: Function and Fate of Duplex RNA in Cells of Higher Eukaryotes

Kumar, M., & Carmichael, G. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.4.1415-1434.1998 · Cited by 320

How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy

Feng, Y., Yao, Z., & Klionsky, D. J. (2015) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.02.002 · Cited by 296

DNA methylomes, histone codes and miRNAs: Tying it all together

Guil, S., & Esteller, M. (2008) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2008.09.005 · Cited by 323

MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation

Yu, J., Chung, K.-H., Deo, M., Thompson, R. C., & Turner, D. L. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.06.002 · Cited by 321

Block of HAC1 mRNA Translation by Long-Range Base Pairing Is Released by Cytoplasmic Splicing upon Induction of the Unfolded Protein Response

Rüegsegger, U., Leber, J. H., & Walter, P. (2001) · Cell · doi:10.1016/s0092-8674(01)00505-0 · Cited by 313

Gene silencing using micro-RNA designed hairpins

McManus, M. T., Petersen, C. P., Haines, B. B., Chen, J., & Sharp, P. A. (2002) · RNA · doi:10.1017/s1355838202024032 · Cited by 311

Molecular Mechanisms of Developmental Timing in C. elegans and Drosophila

Thummel, C. S. (2001) · Developmental Cell · doi:10.1016/s1534-5807(01)00060-0 · Cited by 309

Mechanisms of translational control by the 3′ UTR in development and differentiation

de Moor, C. H., Meijer, H. A., & Lissenden, S. (2005) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2004.11.007 · Cited by 316

The role of microRNAs in endometriosis and associated reproductive conditions

Ohlsson Teague, E. M. C., Print, C. G., & Hull, M. L. (2010) · Human Reproduction Update · doi:10.1093/humupd/dmp034 · Cited by 309

Altered MicroRNA Expression in Cervical Carcinomas

Lee, J., Choi, C. H., Choi, J., Park, Y.-A., Kim, S.-J., Hwang, S. Y., Kim, W. Y., Kim, T., Lee, J., Kim, B., et al. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-1231 · Cited by 313

A Transparent window into biology: A primer on Caenorhabditis elegans

Corsi, A. K. (2015) · WormBook · doi:10.1895/wormbook.1.177.1 · Cited by 328

MicroRNAs in lipid metabolism

Fernandez-Hernando, C. F., Suárez, Y., Rayner, K. J., & Moore, K. J. (2010) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e3283428d9d · Cited by 315

Characterization and Identification of MicroRNA Core Promoters in Four Model Species

Zhou, X., Ruan, J., Wang, G., & Zhang, W. (2007) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0030037 · Cited by 306

Discovering the first microRNA-targeted drug

Lindow, M., & Kauppinen, S. (2012) · The Journal of Cell Biology · doi:10.1083/jcb.201208082 · Cited by 315

RNA-Mediated RNA Degradation and Chalcone Synthase A Silencing in Petunia

Metzlaff, M., O’Dell, M. R., Cluster, P. D., & Flavell, R. B. (1997) · Cell · doi:10.1016/s0092-8674(00)81930-3 · Cited by 304

MicroRNA Regulation of Cardiovascular Development

Cordes, K. R., & Srivastava, D. (2009) · Circulation Research · doi:10.1161/circresaha.108.192872 · Cited by 304

The Oncogenic Role of miR-155 in Breast Cancer

Mattiske, S., Suetani, R. J., Neilsen, P. M., & Callen, D. F. (2012) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-12-0173 · Cited by 305

Molecular mechanisms in signal transduction at the membrane

Groves, J. T., & Kuriyan, J. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1844 · Cited by 312

Diabetes mellitus, a microRNA-related disease?

Guay, C., Roggli, E., Nesca, V., Jacovetti, C., & Regazzi, R. (2011) · Translational research · doi:10.1016/j.trsl.2011.01.009 · Cited by 305

Multilevel Regulation of Gene Expression by MicroRNAs

Makeyev, E. V., & Maniatis, T. (2008) · Science · doi:10.1126/science.1152326 · Cited by 296

Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery

Kim, B., Park, J., & Sailor, M. J. (2019) · Advanced Materials · doi:10.1002/adma.201903637 · Cited by 307

BNPMDA: Bipartite Network Projection for MiRNA–Disease Association prediction

Chen, X., Xie, D., Wang, L., Zhao, Q., You, Z., & Liu, H. (2018) · Bioinformatics · doi:10.1093/bioinformatics/bty333 · Cited by 297

miRNAs in Cancer (Review of Literature)

Smolarz, B., Durczyński, A., Romanowicz, H., Szyłło, K., & Hogendorf, P. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052805 · Cited by 309

miR‐155: an ancient regulator of the immune system

Vigorito, E., Kohlhaas, S. L., Lu, D., & Leyland, R. (2013) · Immunological Reviews · doi:10.1111/imr.12057 · Cited by 296

Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAsPreprint

Lai, E. C., Tam, B., & Rubin, G. M. (2005) · Genes & Development · doi:10.1101/gad.1291905 · Cited by 300

RNAi-Based Therapeutics and Novel RNA Bioengineering Technologies

Traber, G. M., & Yu, A. (2022) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.122.001234 · Cited by 311

Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma

Guo, Y., Chen, Y., Ito, H., Watanabe, A., Ge, X., Kodama, T., & Aburatani, H. (2006) · Gene · doi:10.1016/j.gene.2006.07.011 · Cited by 291

Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans

Zisoulis, D. G., Lovci, M., Wilbert, M. L., Hutt, K. R., Liang, T. Y., Pasquinelli, A. E., & Yeo, G. W.-M. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1745 · Cited by 297

microRNAs Biogenesis, Functions and Role in Tumor Angiogenesis

Annese, T., Tamma, R., Giorgis, M. D., & Ribatti, D. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.581007 · Cited by 299

Diabetes Complications: The MicroRNA Perspective

Kantharidis, P., Wang, B., Carew, R. M., & Lan, H. Y. (2011) · Diabetes · doi:10.2337/db11-0082 · Cited by 292

Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma

Park, J. K., Lee, E. J., Esau, C., & Schmittgen, T. D. (2009) · Pancreas · doi:10.1097/mpa.0b013e3181ba82e1 · Cited by 293

Computational and Experimental Identification of C. elegans microRNAs

Grad, Y. H., Aach, J., Hayes, G. D., Reinhart, B. J., Church, G. M., Ruvkun, G., & Kim, J. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00153-9 · Cited by 286

The MicroRNA-17-92 Family of MicroRNA Clusters in Development and Disease

Concepcion, C. P., Bonetti, C., & Ventura, A. (2012) · The Cancer Journal · doi:10.1097/ppo.0b013e318258b60a · Cited by 286

Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids

Moschos, S. A., Williams, A. E., Perry, M. M., Birrell, M. A., Belvisi, M. G., & Lindsay, M. A. (2007) · BMC Genomics · doi:10.1186/1471-2164-8-240 · Cited by 286

Emerging Role of MicroRNAs in Cardiovascular Biology

Latronico, M. V. G., Catalucci, D., & Condorelli, G. (2007) · Circulation Research · doi:10.1161/circresaha.107.163147 · Cited by 285

Introns: evolution and function

Mattick, J. S. (1994) · Current Opinion in Genetics & Development · doi:10.1016/0959-437x(94)90066-3 · Cited by 285

Functional aspects of animal microRNAs

Williams, A. E. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7355-9 · Cited by 288

From guide to target: molecular insights into eukaryotic RNA-interference machinery

Ipsaro, J. J., & Joshua-Tor, L. (2015) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2931 · Cited by 281

Neuronal Expression of Neural Nitric Oxide Synthase (nNOS) Protein Is Suppressed by an Antisense RNA Transcribed from an NOS Pseudogene

Korneev, S. A., Park, J. H., & O’Shea, M. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-18-07711.1999 · Cited by 278

Genomic organization of microRNAs

Olena, A. F., & Patton, J. G. (2009) · Journal of Cellular Physiology · doi:10.1002/jcp.21993 · Cited by 293

miRNA Targeting: Growing beyond the Seed

Chipman, L. B., & Pasquinelli, A. E. (2019) · Trends in Genetics · doi:10.1016/j.tig.2018.12.005 · Cited by 273

Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysisPreprint

Berezikov, E., van Tetering, G., Verheul, M., van de Belt, J., Laake, L. W. V., Vos, J. B., Verloop, R. E., van de Wetering, M., Guryev, V., Takada, S., et al. (2006) · Genome Research · doi:10.1101/gr.5159906 · Cited by 270

Do natural antisense transcripts make sense in eukaryotes?

Vanhée-Brossollet, C., & Vaquero, C. (1998) · Gene · doi:10.1016/s0378-1119(98)00093-6 · Cited by 271

MicroRNAs: Roles in Regulating Neuroinflammation

Gaudet, A. D., Fonken, L. K., Watkins, L. R., Nelson, R. J., & Popovich, P. G. (2018) · The Neuroscientist · doi:10.1177/1073858417721150 · Cited by 236

Point of care testing for infectious diseases

Chen, H., Liu, K., Zhao, L., & Wang, P. (2019) · Clinica Chimica Acta · doi:10.1016/j.cca.2019.03.008 · Cited by 281

The Developmental Timing Regulator AIN-1 Interacts with miRISCs and May Target the Argonaute Protein ALG-1 to Cytoplasmic P Bodies in C. elegans

Lei, D., Spencer, A., Morita, K., & Han, M. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.07.013 · Cited by 279

Temporal Reciprocity of miRNAs and Their Targets during the Maternal-to-Zygotic Transition in Drosophila

Bushati, N., Stark, A., Brennecke, J., & Cohen, S. M. (2008) · Current Biology · doi:10.1016/j.cub.2008.02.081 · Cited by 271

MicroRNAs, macrocontrol: Regulation of miRNA processing

Ślęzak-Prochazka, I., Durmuş, S., Kroesen, B., & van den Berg, A. (2010) · RNA · doi:10.1261/rna.1804410 · Cited by 271

The piRNA pathway: a fly's perspective on the guardian of the genome

Senti, K.-A., & Brennecke, J. (2010) · Trends in Genetics · doi:10.1016/j.tig.2010.08.007 · Cited by 281

MicroRNA and cancer: Current status and prospective

Wu, W., Sun, M., Zou, G.-M., & Chen, J. (2006) · International Journal of Cancer · doi:10.1002/ijc.22454 · Cited by 266

Recent advances in signal amplification strategy based on oligonucleotide and nanomaterials for microRNA detection-a review

Chen, Y., Huang, K., & Niu, K.-X. (2017) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2017.08.036 · Cited by 263

RNA therapy: rich history, various applications and unlimited future prospects

Kim, Y. (2022) · Experimental & Molecular Medicine · doi:10.1038/s12276-022-00757-5 · Cited by 283

Control of protein synthesis and mRNA degradation by microRNAs

Liu, J. (2008) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2008.01.006 · Cited by 272

A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.Preprint

Ha, I., Wightman, B., & Ruvkun, G. (1996) · Genes & Development · doi:10.1101/gad.10.23.3041 · Cited by 235

Dominant gain-of-function mutations that lead to misregulation of the C. elegans heterochronic gene lin-14, and the evolutionary implications of dominant mutations in pattern-formation genes

Ruvkun, G., Wightman, B., Bürglin, T., & Arasu, P. (1991) · Development · doi:10.1242/dev.113.supplement_1.47 · Cited by 25

Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development.Preprint

Wightman, B., Bürglin, T. R., Gatto, J., Arasu, P., & Ruvkun, G. (1991) · Genes & Development · doi:10.1101/gad.5.10.1813 · Cited by 210

Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28.Preprint

Arasu, P., Wightman, B., & Ruvkun, G. (1991) · Genes & Development · doi:10.1101/gad.5.10.1825 · Cited by 120

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948