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Compensatory plasticity and sensory substitution in the cerebral cortex
Abstract
Cats deprived visually from birth show few overt impairments in their natural behavior. Therefore, they seem well suited as an animal model for the study of compensatory plasticity after early vision loss. It can be demonstrated that binocularly deprived cats show improved abilities of auditory localization, and at least equal tactile behavior compared to normal controls. Within the anterior ectosylvian cortex of binocularly deprived cats, where different sensory modalities come together, the anterior ectosylvian visual area is completely taken over by auditory and somatosensory inputs. Furthermore, the auditory spatial tuning of single units in this cortical region is sharpened significantly as a result of visual deprivation. Somatosensory compensation for early loss of vision can be demonstrated by a hypertrophy of the facial vibrissae, and a corresponding expansion of their central representation in the somatosensory cortex of binocularly deprived animals. The compensatory changes in the cortex can be explained by a reorganization of sensory representations under the guidance of sensorimotor feedback rather than by instruction through an extraneous 'supervisory' signal. These processes might form the neural basis of sensory substitution in blind humans.
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From Designing sensory-substitution devices: Principles, pitfalls and potential1 (2016) · cites this paper as Rauschecker, 1995
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Metadata
- Authors
- Rauschecker, J. P.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Rauschecker, Josef P.
- Venue
- Trends in Neurosciences
- Publisher
- Elsevier BV
- Published
- 1995-01
- Volume
- 18
- Issue
- 1
- Pages
- 36-43
- ISSN
- 0166-2236 (ISSN-L)
- OpenAlex
- W1975230707
- Cited by
- 590
- References
- 85
- Citations by year
- 2026: 8 · 2025: 11 · 2024: 10 · 2023: 9 · 2022: 14 · 2021: 21 · 2020: 18 · 2019: 28 · 2018: 30 · 2017: 23 · 2016: 29 · 2015: 22 · 2014: 18 · 2013: 20 · 2012: 21
- FWCI
- 3.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Neurosciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Multisensory perception and integration
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Keywords
- compensatory plasticity, sensory substitution, congenital blindness, sound localization, tactile behavior, somatosensory cortex, sensorimotor feedback, cross-modal plasticity
- MeSH terms
- Animals, Auditory Cortex, Blindness, Cats, Cerebral Cortex, Disease Models, Animal, Humans, Neuronal Plasticity, Somatosensory Cortex
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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What counts as a claim ›How we measure confidence ›How we check this ›
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