Cited by 1,153Gut microbiota and healthProbiotics and Fermented FoodsInfant Nutrition and Health

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The indigenous gastrointestinal microflora

Berg, R·1996·Trends in Microbiology

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Abstract

The indigenous gastrointestinal (GI) tract microflora has profound effects on the anatomical, physiological and immunological development of the host. The indigenous microflora stimulates the host immune system to respond more quickly to pathogen challenge and, through bacterial antagonism, inhibits colonization of the GI tract by overt exogenous pathogens. Indigenous GI bacteria are also opportunistic pathogens and can translocate across the mucosal barrier to cause systemic infection in debilitated hosts.

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Crossref · 10.1016/0966-842x(96)10057-3

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Background
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Background
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“The indigenous gastrointestinal tract microflora has profound effects on the anatomical, physiological and immunological development of the host [91].”
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“The results obtained in the present study confirm these data and the established protective effect of the normal microbiota against enteropathogenic bacteria (Berg 1996).”
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“Only a fraction of the estimated 400–500 bacteria species living in the human intestine [38] have been sequenced and therefore we may not have been able to identify any other members of this clade due to sampling limitations.”
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“Colon contain a complex and dynamic microbial ecosystem, with big concentration of bacteria coming up to more than 1011 to 1012 units that form colonies for milliliters (UFCmL–1) (Berg, 1996).”
Background
Immune enhancing effects of Lactobacillus acidophilus LAFTI L10 and Lactobacillus paracasei LAFTI L26 in mice
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Background
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Background
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Background
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“The gut microbiota contains abundant bacterial species with diverse structural composition of LPS (Berg 1996).”
Background

Authors: Berg, R.
Affiliations: Louisiana State University (US)
Corresponding author: Berg, R
Venue: Trends in Microbiology
Publisher: Elsevier BV
Published: 1996-11
Volume: 4
Issue: 11
Pages: 430-435
ISSN: 0966-842X (ISSN-L)
DOI: 10.1016/0966-842x(96)10057-3
OpenAlex: W2087484128
Cited by: 1,153
References: 17
Citations by year: 2026: 12 · 2025: 24 · 2024: 24 · 2023: 27 · 2022: 34 · 2021: 45 · 2020: 50 · 2019: 56 · 2018: 41 · 2017: 59 · 2016: 54 · 2015: 42 · 2014: 59 · 2013: 39 · 2012: 54
FWCI: 3.03
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Microbiology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
Keywords: gastrointestinal tract, host-pathogen interaction, bacterial antagonism, colonization resistance, opportunistic pathogens, mucosal barrier, systemic infection, host-microbe interactions
MeSH terms: Animals, Digestive System, Ecology, Humans, Mouth, Bacterial Physiological Phenomena

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