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The Formation of Estrogens by Central Neuroendocrine Tissues
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“Early in the study of steroid-induced sexual differentiation, it was discovered that masculinization—initially attributed entirely to the effects of androgens—actually occurred through many estrogen-dependent mechanisms.”
From Developmental origins of sex differences in the neural circuitry of play (2020) · cites this paper as Naftolin et al., 1975
In the citing paper
“Neurons in some regions of the brain express high levels of the enzyme aromatase, which converts testosterone into estradiol (Naftolin et al., 1975; McEwen et al., 1977).”
From Developmental origins of sex differences in the neural circuitry of play (2020) · cites this paper as Naftolin et al., 1975
Citations
Cites
CONVERSION OF ANDROSTENEDIONE TO ESTRONE BY HUMAN FAT TISSUE
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Metadata
- Authors
- NAFTOLIN, F., RYAN, K. J., DAVIES, I. J., REDDY, V. V., FLORES, F., PETRO, Z., KUHN, M., WHITE, R. J., TAKAOKA, Y., & WOLIN, L.
- Affiliations
- Harvard University (US)
- Case Western Reserve University (US)
- Venue
- Proceedings of the 1974 Laurentian Hormone Conference
- Publisher
- Elsevier
- Published
- 1975
- Volume
- 31
- Pages
- 295-319
- OpenAlex
- W1596855324
- Cited by
- 793
- References
- 1
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 6 · 2023: 4 · 2022: 10 · 2021: 11 · 2020: 10 · 2019: 5 · 2018: 10 · 2017: 8 · 2016: 11 · 2015: 7 · 2014: 12 · 2013: 10 · 2012: 10
- FWCI
- 22.91
- Type
- conference paper
- Language
- en
- Open access
- closed
- Locations
- Elsevier eBooks (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Life Sciences › Neuroscience › Neurology › Neurology and Historical Studies
- Keywords
- estrogen synthesis, brain differentiation, rodent brain, antiestrogens, LH-releasing factor
- MeSH terms
- Amygdala, Animals, Haplorhini, Brain, Castration, Cell Differentiation, Estradiol, Estrone, Female, Fetus, Hippocampus, Humans, Hypothalamus, Macaca mulatta, Male, Organ Specificity, Pregnancy, Progesterone, Sex Factors, Species Specificity, Testosterone
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