Personality-dependent effects of oxytocin: greater social benefits for high alexithymia scorers
Open accessAbstract
Originally known for its role in labor and lactation, oxytocin (OT) has recently been shown to facilitate social behaviour by improving socio-emotional abilities. However, whether OT is equally beneficial to all people, or whether is it particularly beneficial to less emotionally/socially competent (i.e., high alexithymia) individuals it is not yet known. We investigated the effects of OT on individuals of varying socio-emotional ability by randomly assigning sixty male students to receive either oxytocin (OT) or a placebo (PL), and had them perform the Reading the Mind in the Eyes test (RMET). Results showed that whereas the performance of lower alexithymia individuals was equally good in both OT and PL conditions, the performance of higher alexithymia people was better under OT than PL. These results suggest that the effects of OT are not only context-dependent-as recently shown-but also personality dependent. They also provide new insights into the remediation of socio-emotional deficits.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Enhanced prosocial effects of intranasally administered OT are especially pronounced for individuals with socio-emotional deficits, such as Asperger syndrome or high alexithymia.
“It appears that the enhanced prosocial effects of intranasally administered OT are especially pronounced for individuals suffering from socio-emotional deficits, as is the case for individuals with Asperger syndrome (Andari et al., 2010) or high alexithymia (Luminet et al., 2011).”
From The effect of oxytocin on cooperation in a prisoner's dilemma depends on the social context and a person's social value orientation (2014) · cites this paper as Luminet et al., 2011
Cites
Measuring individual differences in empathy: Evidence for a multidimensional approach.
Davis, M. H. (1983) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.44.1.113 · Cited by 10,272 · see citing works
The brief symptom inventory: an introductory report.
Derogatis, L. R., & Melisaratos, N. (1983) · Psychological Medicine · doi:10.1017/s0033291700048017 · Cited by 6,650 · see citing works
Bagby, R. M., Parker, J. D. A., & Taylor, G. J. (1994) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(94)90005-1 · Cited by 5,293 · see citing works
Baron‐Cohen, S., Wheelwright, S., Hill, J., Raste, Y., & Plumb, I. (2001) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00715 · Cited by 4,555 · cited 3× · see citing works
“, 2009) and clinical groups known to have deficits in socio-emotional abilities, such as schizophrenia and autism disorders (Baron-Cohen et al., 2001; Craig et al., 2004).”
BackgroundMethodBaron‐Cohen, S., Wheelwright, S. J., Hill, J., Raste, Y., & Plumb, I. (2001) · PubMed · Cited by 4,313 · see citing works
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690 · see citing works
Four ways five factors are basic
Costa, P., & McCrae, R. (1992) · Personality and Individual Differences · doi:10.1016/0191-8869(92)90236-i · Cited by 3,269 · see citing works
The twenty-item Toronto Alexithymia scale—II. Convergent, discriminant, and concurrent validity
Bagby, R. M., Taylor, G. J., & Parker, J. D. A. (1994) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(94)90006-x · Cited by 2,431 · see citing works
Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00465-7 · Cited by 2,091 · see citing works
Shamay-Tsoory, S. G., Aharon-Peretz, J., & Perry, D. (2009) · Brain · doi:10.1093/brain/awn279 · Cited by 1,544 · see citing works
(1997) · Medical Entomology and Zoology · Cited by 1,407 · see citing works
Oxytocin improves “mind-reading” in humans
Domes, G., Heinrichs, M., Michel, A., Berger, C., & Herpertz, S. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.07.015 · Cited by 1,298 · see citing works
Oxytocin shapes the neural circuitry of trust and trust adaptation in humans
Baumgartner, T., Heinrichs, M., Vonlanthen, A., Fischbacher, U., & Fehr, E. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.009 · Cited by 1,258 · see citing works
The neurobiology of attachment
Insel, T. R., & Young, L. J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35053579 · Cited by 1,173 · see citing works
The Neuropeptide Oxytocin Regulates Parochial Altruism in Intergroup Conflict Among Humans
De Dreu, C. K. W., Greer, L. L., Handgraaf, M. J. J., Shalvi, S., Van Kleef, G. A., Baas, M., Ten Velden, F. S., Van Dijk, E., & Feith, S. W. W. (2010) · Science · doi:10.1126/science.1189047 · Cited by 1,148 · see citing works
Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders.
Guastella, A. J., Einfeld, S. L., Gray, K. M., Rinehart, N. J., Tonge, B. J., Lambert, T. J., & Hickie, I. B. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.020 · Cited by 962 · see citing works
Oxytocin increases generosity in humans
Zak, P. J., Stanton, A. A., & Ahmadi, S. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001128 · Cited by 831 · see citing works
Oxytocin, vasopressin, and human social behavior
Heinrichs, M., von Dawans, B., & Domes, G. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.05.005 · Cited by 799 · see citing works
Oxytocin increases gaze to the eye region of human faces
Guastella, A. J., Mitchell, P. B., & Dadds, M. R. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.06.026 · Cited by 798 · see citing works
Feldman, R., Weller, A., Zagoory-Sharon, O., & Levine, A. (2007) · Psychological Science · doi:10.1111/j.1467-9280.2007.02010.x · Cited by 787 · see citing works
Ditzen, B., Schaer, M., Gabriel, B., Bodenmann, G., Ehlert, U., & Heinrichs, M. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.10.011 · Cited by 784 · see citing works
Oxytocin Increases Retention of Social Cognition in Autism
Hollander, E., Bartz, J., Chaplin, W., Phillips, A., Sumner, J., Soorya, L., Anagnostou, E., & Wasserman, S. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.030 · Cited by 693 · see citing works
New Trends in Alexithymia Research
Taylor, G. J., & Bagby, R. M. (2004) · Psychotherapy and Psychosomatics · doi:10.1159/000075537 · Cited by 653 · see citing works
Empathy toward strangers triggers oxytocin release and subsequent generosity
Barraza, J. A., & Zak, P. J. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04504.x · Cited by 489 · see citing works
Oxytocin selectively improves empathic accuracy
Bartz, J. A., Zaki, J., Bolger, N., Hollander, E., Ludwig, N. N., Kolevzon, A., & Ochsner, K. N. (2010) · Psychological Science · doi:10.1177/0956797610383439 · Cited by 442 · see citing works
Disorders of affect regulation: Alexithymia in medical and psychiatric illness.
Deary, I. J. (1998) · Journal of Psychosomatic Research · Cited by 431 · see citing works
Emotion-processing deficits in eating disorders
Bydlowski, S., Corcos, M., Jeammet, P., Paterniti, S., Berthoz, S., Laurier, C., Chambry, J., & Consoli, S. M. (2005) · International Journal of Eating Disorders · doi:10.1002/eat.20132 · Cited by 348 · see citing works
Facial expression recognition in people with medicated and unmedicated Parkinson’s disease
Sprengelmeyer, R., Young, A. W., Mahn, K., Schroeder, U., Woitalla, D., Büttner, T., Kuhn, W., & Przuntek, H. (2003) · Neuropsychologia · doi:10.1016/s0028-3932(02)00295-6 · Cited by 294 · see citing works
Luminet, O., Bagby, R. M., & Taylor, G. J. (2001) · Psychotherapy and Psychosomatics · doi:10.1159/000056263 · Cited by 288 · see citing works
Attachment, aggression and affiliation: the role of oxytocin in female social behavior
Campbell, A. (2008) · Biological Psychology · doi:10.1016/j.biopsycho.2007.09.001 · Cited by 269 · see citing works
Alexithymia in the interpersonal domain: A general deficit of empathy?
Grynberg, D., Luminet, O., Corneille, O., Grèzes, J., & Berthoz, S. (2010) · Personality and Individual Differences · doi:10.1016/j.paid.2010.07.013 · Cited by 260 · see citing works
Alexithymia and Depression: A Prospective Study of Patients With Major Depressive Disorder
Honkalampi, K. M., Hintikka, J. J., Laukkanen, E., & Viinamäki, J. L. H. (2001) · Psychosomatics · doi:10.1176/appi.psy.42.3.229 · Cited by 249 · see citing works
Enhanced social interactions in rats following chronic, centrally infused oxytocin
Witt, D. M., Winslow, J. T., & Insel, T. R. (1992) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(92)90418-f · Cited by 244 · see citing works
Cognitive and emotional characteristics of alexithymia: a review of neurobiological studies.
Larsen, J., Brand, N., Bermond, B., & Hijman, R. (2003) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(02)00466-x · Cited by 239 · see citing works
Craig, J. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(03)00154-3 · Cited by 219 · see citing works
Oxytocin makes people trusting, not gullible
Mikolajczak, M., Gross, J. J., Lane, A., Corneille, O., de Timary, P., & Luminet, O. (2010) · Psychological Science · doi:10.1177/0956797610377343 · Cited by 216 · see citing works
Attentional Bias, Emotion Recognition, and Emotion Regulation in Anorexia: State or Trait?
Harrison, A., Tchanturia, K., & Treasure, J. L. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.04.037 · Cited by 215 · see citing works
Whissell, C. (2009) · Psychological Reports · doi:10.2466/pr0.105.2.509-521 · Cited by 215 · see citing works
Córdova, J. V., Gee, C. B., & Warren, L. Z. (2005) · Journal of Social and Clinical Psychology · doi:10.1521/jscp.24.2.218.62270 · Cited by 214 · see citing works
Goldman, M. B., Marlow-O’Connor, M., Torres, I. J., & Carter, C. S. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.09.019 · Cited by 211 · see citing works
Relation Between Alexithymia and the Five-Factor Model of Personality: A Facet-Level Analysis
Luminet, O., Bagby, R. M., Wagner, H. L., Taylor, G. J., & Parker, J. D. A. (1999) · Journal of Personality Assessment · doi:10.1207/s15327752jpa7303_4 · Cited by 201 · see citing works
Uvnäs‐Moberg, K., & Petersson, M. (2005) · Zeitschrift für psychosomatische Medizin und Psychotherapie · doi:10.13109/zptm.2005.51.1.57 · Cited by 200 · see citing works
Social Interaction Deficits Caused by Chronic Phencyclidine Administration are Reversed by Oxytocin
Lee, P. R., Brady, D. L., Shapiro, R. A., Dorsa, D. M., & Koenig, J. I. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300722 · Cited by 199 · see citing works
Alexithymia in women and men hospitalized for psychoactive substance dependence
Haviland, M. G., HENDRYX, M. S., Shaw, D. G., & Henry, J. P. (1994) · Comprehensive Psychiatry · doi:10.1016/0010-440x(94)90056-n · Cited by 190 · see citing works
Selective disruption of the recognition of facial expressions of anger
Lawrence, A. D., Calder, A. J., McGowan, S., & Grasby, P. M. (2002) · Neuroreport · doi:10.1097/00001756-200205070-00029 · Cited by 183 · see citing works
A preliminary investigation of alexithymia in men with psychoactive substance dependence
(1990) · American Journal of Psychiatry · doi:10.1176/ajp.147.9.1228 · Cited by 176 · see citing works
Alexithymia and risk of death in middle-aged men
Kauhanen, J., Kaplan, G. A., Cohen, R. D., Julkunen, J., & Salonen, J. T. (1996) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(96)00226-7 · Cited by 156 · see citing works
Men and psychotherapy: An investigation of alexithymia, intimacy, and masculine gender roles.
Fischer, A. R., & Good, G. E. (1997) · Psychotherapy · doi:10.1037/h0087646 · Cited by 149 · see citing works
Alexithymia and perception of facial expressions of emotion
Prkachin, G. C., Casey, C., & Prkachin, K. M. (2008) · Personality and Individual Differences · doi:10.1016/j.paid.2008.11.010 · Cited by 148 · see citing works
Alexithymia and body image in adult outpatients with binge eating disorder
Carano, A., Berardis, D. D., Gambi, F., Paolo, C. D., Campanella, D., Pelusi, L., Sepede, G., Mancini, E., Rovere, R. L., Salini, G., et al. (2006) · International Journal of Eating Disorders · doi:10.1002/eat.20238 · Cited by 141 · see citing works
de Timary, P., Luts, A., Hers, D., & Luminet, O. (2007) · Psychiatry Research · doi:10.1016/j.psychres.2006.12.008 · Cited by 136 · see citing works
Kauhanen, J., Kaplan, G. A., Julkunen, J., Wilson, T. W., & Salonen, J. T. (1993) · Comprehensive Psychiatry · doi:10.1016/0010-440x(93)90019-z · Cited by 133 · see citing works
Alexithymia and satisfaction in intimate relationships
Humphreys, T. P., Wood, L. M., & Parker, J. D. A. (2009) · Personality and Individual Differences · doi:10.1016/j.paid.2008.09.002 · Cited by 130 · see citing works
Mikolajczak, M., Pinon, N., Lane, A., de Timary, P., & Luminet, O. (2010) · Biological Psychology · doi:10.1016/j.biopsycho.2010.05.010 · Cited by 129 · see citing works
Depressive personality dimensions and alexithymia in eating disorders
Speranza, M., Corcos, M., Loas, G., Stéphan, P., Guilbaud, O., Pérez-Díaz, F., Vénisse, J.-L., Bizouard, P., Halfon, O., Flament, M. F., et al. (2005) · Psychiatry Research · doi:10.1016/j.psychres.2005.04.001 · Cited by 129 · see citing works
What about theory of mind after severe brain injury?
Havet-Thomassin, V., Allain, P., Etcharry‐Bouyx, F., & Gall, D. L. (2006) · Brain Injury · doi:10.1080/02699050500340655 · Cited by 118 · see citing works
Relationship between Alexithymia and Panic Disorder: A Longitudinal Study to Answer an Open Question
Marchesi, C., Fontò, S., Balista, C., Cimmino, C., & Maggini, C. (2004) · Psychotherapy and Psychosomatics · doi:10.1159/000082028 · Cited by 118 · see citing works
Parker, P. D., Prkachin, K. M., & Prkachin, G. C. (2005) · Journal of Personality · doi:10.1111/j.1467-6494.2005.00339.x · Cited by 113 · see citing works
Is alexithymia affected by situational stress or is it a stable trait related to emotion regulation?
Mikolajczak, M., & Luminet, O. (2006) · Personality and Individual Differences · doi:10.1016/j.paid.2005.10.020 · Cited by 108 · see citing works
de Timary, P., Roy, E., Luminet, O., Fillée, C., & Mikolajczak, M. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.06.005 · Cited by 104 · see citing works
Loneliness, Interpersonal Distrust, and Alexithymia in University Students 1
Qualter, P., Quinton, S., Wagner, H. L., & Brown, S. (2009) · Journal of Applied Social Psychology · doi:10.1111/j.1559-1816.2009.00491.x · Cited by 99 · see citing works
Confirmatory Factor Analysis of the French Translation of the 20-Item Toronto Alexithymia Scale
Loas, G., Parker, J. D. A., Otmani, O., Verrier, A., & Fremaux, D. (1997) · Perceptual and Motor Skills · doi:10.2466/pms.1997.85.3.1018 · Cited by 96 · see citing works
Weinryb, R. M., Gustavsson, P. J., Hellström, C., Andersson, E., Broberg, A. G., & Rylander, G. (1996) · Personality and Individual Differences · doi:10.1016/0191-8869(95)00137-u · Cited by 89 · see citing works
Hosoi, M., Molton, I. R., Jensen, M. P., Ehde, D. M., Amtmann, S., O'Brien, S., 有村, 達., & Kubo, C. (2010) · Pain · doi:10.1016/j.pain.2010.02.012 · Cited by 79 · see citing works
Alexithymia and Cognitive Dysfunctions in Patients with Panic Disorder
Galderisi, S., Mancuso, F., Mucci, A., S., G., Zamboli, R., & Maj, M. (2008) · Psychotherapy and Psychosomatics · doi:10.1159/000119738 · Cited by 77 · see citing works
Lumley, M. A., Downey, K. K., Stettner, L. J., Wehmer, F., & Pomerleau, O. F. (2010) · Psychotherapy and Psychosomatics · doi:10.1159/000288884 · Cited by 51 · see citing works
Viinamäki, H. T., Haatainen, K. M., Honkalampi, K. M., Tanskanen, A. J., Koivumaa-Honkanen, H. T., Antikainen, R., Valkonen‐Korhonen, M., & Hintikka, J. J. (2006) · Nordic Journal of Psychiatry · doi:10.1080/08039480600937801 · Cited by 26 · see citing works
van Kerkhoven, L. A. S., van Rossum, L. G. M., van Oijen, M. G. H., Tan, A. C. I. T. L., Witteman, E. M., Laheij, R. J. F., & Jansen, J. B. �. �. (2006) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-200603000-00005 · Cited by 16 · see citing works
Oxytocin makes us trusting but not gulliblePreprint
Mikolajczak, M., Lane, A., Gross, J. J., de Timary, P., & Luminet, O. (2009) · Nature Precedings · doi:10.1038/npre.2009.3790.1 · Cited by 3 · see citing works
Alexithymie und interpersonale Beziehungsprobleme
Spitzer, C., Siebel, U., Barnow, S., Grabe, H. J., & Freyberger, H. J. (2005) · PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie · doi:10.1055/s-2005-863424 · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Autism, oxytocin and interoception
Quattrocki, E., & Friston, K. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.09.012 · Cited by 393 · see citing works
Alexithymia, not autism, is associated with impaired interoception
Shah, P., Hall, R., Catmur, C., & Bird, G. (2016) · Cortex · doi:10.1016/j.cortex.2016.03.021 · Cited by 326 · see citing works
Quintana, D. S., Lischke, A., Grace, S., Scheele, D., Ma, Y., & Becker, B. (2021) · Molecular Psychiatry · doi:10.1038/s41380-020-00864-7 · Cited by 263 · see citing works
Meta-analysis of the effects of intranasal oxytocin on interpretation and expression of emotions
Leppanen, J., Ng, K. W., Tchanturia, K., & Treasure, J. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.04.010 · Cited by 188 · see citing works
Oxytocin, testosterone, and human social cognition
Crespi, B. J. (2015) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12175 · Cited by 175 · see citing works
Cognitive-emotional processing in alexithymia: an integrative review
Luminet, O., Nielson, K. A., & Ridout, N. (2021) · Cognition & Emotion · doi:10.1080/02699931.2021.1908231 · Cited by 149 · see citing works
MacDonald, K., MacDonald, T. M., Brüne, M., Lamb, K., Wilson, M. P., Golshan, S., & Feifel, D. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.05.014 · Cited by 140 · see citing works
Lane, A., Luminet, O., Nave, G., & Mikolajczak, M. (2016) · Journal of Neuroendocrinology · doi:10.1111/jne.12384 · Cited by 134 · see citing works
Shamay-Tsoory, S. G., Abu-Akel, A., Palgi, S., Sulieman, R., Fischer-Shofty, M., Levkovitz, Y., & Decety, J. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.09.015 · Cited by 123 · see citing works
Oxytocin in the socioemotional brain: implications for psychiatric disorders
Kirsch, P. (2015) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2015.17.4/pkirsch · Cited by 122 · see citing works
Brewer, R., Happé, F., Cook, R., & Bird, G. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.07.006 · Cited by 117 · see citing works
Trevisan, D. A., Bowering, M., & Birmingham, E. (2016) · Molecular Autism · doi:10.1186/s13229-016-0108-6 · Cited by 107 · see citing works
Four decades of research on alexithymia: moving toward clinical applications
Samur, D., Tops, M., Schlinkert, C., Quirin, M., Cuijpers, P., & Koole, S. L. (2013) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00861 · Cited by 104 · see citing works
Konrath, S., Corneille, O., Bushman, B. J., & Luminet, O. (2014) · Journal of Nonverbal Behavior · doi:10.1007/s10919-013-0164-y · Cited by 103 · see citing works
Self-citationDeclerck, C. H., Boone, C., & Kiyonari, T. (2014) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nst040 · Cited by 96 · see citing works
Oxytocin effects in schizophrenia: Reconciling mixed findings and moving forward
Bradley, E., & Woolley, J. D. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.05.007 · Cited by 88 · see citing works
Does oxytocin affect mind-reading? A replication study
Radke, S., & de Bruijn, E. R. A. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.06.006 · Cited by 82 · see citing works
Attachment and Personality Disorders: A Short Review
Lorenzini, N., & Fonagy, P. (2013) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.11.2.155 · Cited by 89 · see citing works
The many faces of oxytocin: Implications for psychiatry
Zik, J. B., & Roberts, D. L. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.11.048 · Cited by 85 · see citing works
Oxytocin increases empathy to pain when adopting the other-but not the self-perspective
Abu-Akel, A., Palgi, S., Klein, E., Decety, J., & Shamay-Tsoory, S. (2015) · Social Neuroscience · doi:10.1080/17470919.2014.948637 · Cited by 83 · see citing works
Feeser, M., Fan, Y., Weigand, A., Hahn, A., Gärtner, M., Böker, H., Grimm, S., & Bajbouj, M. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.12.015 · Cited by 74 · see citing works
Luminet, O., Nielson, K. A., & Ridout, N. (2021) · Cognition & Emotion · doi:10.1080/02699931.2021.1916442 · Cited by 76 · see citing works
Huffmeijer, R., van IJzendoorn, M. H., & Bakermans‐Kranenburg, M. J. (2012) · Gerontology · doi:10.1159/000341333 · Cited by 71 · see citing works
Schneider-Hassloff, H., Straube, B., Jansen, A., Nuscheler, B., Wemken, G., Witt, S. H., Rietschel, M., & Kircher, T. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.04.009 · Cited by 71 · see citing works
Bartz, J. A., Lydon, J. E., Kolevzon, A., Zaki, J., Hollander, E., Ludwig, N., & Bolger, N. (2015) · Psychological Science · doi:10.1177/0956797615580279 · Cited by 70 · see citing works
Eckstein, M., Markett, S. A., Kendrick, K. M., Ditzen, B., Liu, F., Hurlemann, R., & Becker, B. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.01.078 · Cited by 69 · see citing works
Oxytocin improves synchronisation in leader-follower interaction
Gebauer, L., Witek, M. A. G., Hansen, N. C., Thomas, J., Konvalinka, I., & Vuust, P. (2016) · Scientific Reports · doi:10.1038/srep38416 · Cited by 64 · see citing works
Cerniglia, L., Bartolomeo, L. D., Capobianco, M., Russo, S. L. M. L., Festucci, F., Tambelli, R., Adriani, W., & Cimino, S. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00212 · Cited by 62 · see citing works
Failed Replication of Oxytocin Effects on Trust: The Envelope Task Case
Lane, A., Mikolajczak, M., Treinen, E., Samson, D., Corneille, O., de Timary, P., & Luminet, O. (2015) · PLOS ONE · doi:10.1371/journal.pone.0137000 · Cited by 61 · see citing works
The relationship between alexithymia and theory of mind: A systematic review
Pisani, S., Murphy, J., Conway, J. R., Millgate, E., Catmur, C., & Bird, G. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.09.036 · Cited by 63 · see citing works
Dramatic Improvement in Sexual Function Induced by Intranasal Oxytocin
MacDonald, K. S., & Feifel, D. (2012) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2012.02703.x · Cited by 59 · see citing works
Oxytocin Selectively Improves Empathic Accuracy: A Replication in Men and Novel Insights in Women
Bartz, J. A., Nitschke, J. P., Krol, S. A., & Tellier, P. (2019) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2019.01.014 · Cited by 55 · see citing works
Oxytocin secretion is pulsatile in men and is related to social-emotional functioning
Baskaran, C., Plessow, F., Silva, L., Asanza, E., Marengi, D., Eddy, K. T., Sluss, P. M., Johnson, M. L., Misra, M., & Lawson, E. A. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2017.07.486 · Cited by 50 · see citing works
The interplay of oxytocin and sex hormones
Quintana, D. S., Glaser, B. D., Kang, H., Kildal, E. S.-M., Audunsdottir, K., Sartorius, A. M., & Barth, C. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105765 · Cited by 54 · see citing works
Riem, M. M. E., Bakermans‐Kranenburg, M. J., & van IJzendoorn, M. H. (2016) · Attachment & Human Development · doi:10.1080/14616734.2016.1149872 · Cited by 48 · see citing works
Pavlova, M. A., & Sokolov, A. A. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104755 · Cited by 50 · see citing works
Riem, M. M. E., Bakermans‐Kranenburg, M. J., Voorthuis, A., & van IJzendoorn, M. H. (2014) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2014.01.014 · Cited by 46 · see citing works
Kiss, I., Levy‐Gigi, E., & Kéri, S. (2011) · Biological Psychology · doi:10.1016/j.biopsycho.2011.08.005 · Cited by 45 · see citing works
Haram, M., Tesli, M., Bettella, F., Djurovic, S., Andreassen, O. A., & Melle, I. S. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00009 · Cited by 42 · see citing works
Theodoridou, A., Rowe, A. C., & Mohr, C. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00197 · Cited by 40 · see citing works
“…anxiety disorder, and schizophrenia (Caldwell et al., 2009; Guastella et al., 2009b; Bartz et al., 2010; Feifel et al., 2010; Rubin et al., 2010; Luminet et al., 2011; Pedersen et al., 2011; Hall et al., 2012) as it has already been shown in autism spectrum disorders (Andari et al., 2010;…”
BackgroundHuffmeijer, R., Alink, L. R. A., Mattie Tops, A., Grewen, K., Light, K. C., Bakermans‐Kranenburg, M. J., & van IJzendoorn, M. H. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.11.008 · Cited by 42 · see citing works
Abraham, E., Hendler, T., Zagoory-Sharon, O., & Feldman, R. (2019) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2018.02.001 · Cited by 38 · see citing works
Effects of Intranasal Oxytocin on the Interpretation and Expression of Emotions in Anorexia Nervosa
Leppänen, J., Cardi, V., Ng, K. W., Paloyelis, Y., Stein, D. J., Tchanturia, K., & Treasure, J. L. (2017) · Journal of Neuroendocrinology · doi:10.1111/jne.12458 · Cited by 40 · see citing works
Low oxytocin levels are related to alexithymia in anorexia nervosa
Schmelkin, C., Plessow, F., Thomas, J. J., Gray, E. K., Marengi, D. A., Pulumo, R., Silva, L. E., Miller, K. K., Hadjikhani, N. K., Franko, D. L., et al. (2017) · International Journal of Eating Disorders · doi:10.1002/eat.22784 · Cited by 37 · see citing works
From Oxytocin to Compassion: The Saliency of Distress
Kucerova, B., Levit‐Binnun, N., Gordon, I., & Golland, Y. (2023) · Biology · doi:10.3390/biology12020183 · Cited by 35 · see citing works
Impact of intranasal oxytocin on interoceptive accuracy in alcohol users: an attentional mechanism?
Betka, S., van Praag, C. G., Paloyelis, Y., Bond, R., Pfeifer, G., Sequeira, H., Duka, T., & Critchley, H. (2018) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsy027 · Cited by 30 · see citing works
Pfundmair, M., Aydin, N., Frey, D., & Echterhoff, G. (2014) · Journal of Experimental Social Psychology · doi:10.1016/j.jesp.2014.07.016 · Cited by 31 · see citing works
Deciphering the modulatory role of oxytocin in human altruism
Hurlemann, R., & Marsh, N. (2017) · Reviews in the Neurosciences · doi:10.1515/revneuro-2016-0061 · Cited by 31 · see citing works
Effects of Intranasal Oxytocin on Long‐Term Memory in Healthy Humans: A Systematic Review
Brambilla, M., Manenti, R., de Girolamo, G., Adenzato, M., Bocchio‐Chiavetto, L., & Cotelli, M. (2016) · Drug Development Research · doi:10.1002/ddr.21343 · Cited by 31 · see citing works
Feeser, M., Fan, Y., Weigand, A., Hahn, A., Gärtner, M., Aust, S., Böker, H., Bajbouj, M., & Grimm, S. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3631-1 · Cited by 28 · see citing works
Emotion Knowledge and Emotion Regulation in Alexithymia
Luminet, O., & Zamariola, G. (2018) · Cambridge University Press eBooks · doi:10.1017/9781108241595.006 · Cited by 26 · see citing works
Alexithymia, Fear of Intimacy, and Relationship Satisfaction
Lyvers, M., Pickett, L. L., Needham, K., & Thorberg, F. A. (2021) · Journal of Family Issues · doi:10.1177/0192513x211010206 · Cited by 23 · see citing works
Riem, M. M. E., Kunst, L. E., Steenbakkers, F. D. F., Kir, M., Sluijtman, A., Karreman, A., & Bekker, M. H. J. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.06.012 · Cited by 25 · see citing works
Straccia, M. A., Teed, A. R., Katzman, P. L., Tan, K. M., Parrish, M. H., Irwin, M. R., Eisenberger, N. I., Lieberman, M. D., & Tabak, B. A. (2021) · Psychological Medicine · doi:10.1017/s0033291721004104 · Cited by 25 · see citing works
Intranasal oxytocin reduces social perception in women: Neural activation and individual variation
Hecht, E. E., Robins, D. L., Gautam, P., & King, T. Z. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.12.046 · Cited by 24 · see citing works
Strauss, G. P., Granholm, E. L., Holden, J. L., Ruiz, I., Gold, J. M., Kelly, D. L., & Buchanan, R. W. (2018) · Psychological Medicine · doi:10.1017/s0033291718002465 · Cited by 25 · see citing works
Effects of intranasal oxytocin prior to encoding and retrieval on recognition memory
Weigand, A., Feeser, M., Gärtner, M., Brandt, E. S. L., Fan, Y., Fuge, P., Böker, H., Bajbouj, M., & Grimm, S. (2013) · Psychopharmacology · doi:10.1007/s00213-012-2962-z · Cited by 23 · see citing works
Valence in the Reading the Mind in the Eyes task.
Hudson, C. C., Shamblaw, A. L., Harkness, K. L., & Sabbagh, M. A. (2020) · Psychological Assessment · doi:10.1037/pas0000818 · Cited by 21 · see citing works
Samur, D., Luminet, O., & Koole, S. L. (2017) · Poetics · doi:10.1016/j.poetic.2017.09.002 · Cited by 17 · see citing works
Preti, A., Sancassiani, F., Cadoni, F., & Carta, M. G. (2013) · Clinical Practice and Epidemiology in Mental Health · doi:10.2174/1745017901309010069 · Cited by 17 · see citing works
Hormonal abnormalities in alexithymia
Goerlich, K. S., & Votinov, M. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.1070066 · Cited by 15 · see citing works
Social and Interpersonal Implications of Alexithymia
Grynberg, D., Berthoz, S., & Bird, G. (2018) · Cambridge University Press eBooks · doi:10.1017/9781108241595.013 · Cited by 17 · see citing works
The use of intranasal oxytocin in the treatment of eating disorders
Malewska-Kasprzak, M., Jowik, K., & Tyszkiewicz‐Nwafor, M. (2023) · Neuropeptides · doi:10.1016/j.npep.2023.102387 · Cited by 13 · see citing works
Haram, M., Tesli, M., Dieset, I., Steen, N. E., Røssberg, J. I., Djurovic, S., Andreassen, O. A., & Melle, I. S. (2014) · Neuropsychobiology · doi:10.1159/000356965 · Cited by 13 · see citing works
The role of oxytocin and alexithymia in the therapeutic process
Quirin, M., Carter, C. S., Bode, R. C., Düsing, R., Radtke, E. L., & Mattie Tops, A. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.01074 · Cited by 13 · see citing works
Polk, R. J., Horta, M., Lin, T., Porges, E. C., Ojeda, M., Nazarloo, H. P., Carter, C. S., & Ebner, N. C. (2022) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2021.0048 · Cited by 11 · see citing works
Schmidt, A., Davies, C., Paloyelis, Y., Meyer, N., Micheli, A. D., Ramella‐Cravaro, V., Provenzani, U., Aoki, Y. Y., Rutigliano, G., Cappucciati, M., et al. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-00885-4 · Cited by 13 · see citing works
Mayer, A. V., Preckel, K., Ihle, K., Piecha, F. A., Junghanns, K., Reiche, S., Rademacher, L., Müller‐Pinzler, L., Stolz, D. S., Kamp‐Becker, I., et al. (2021) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2021.10.004 · Cited by 12 · see citing works
Stark, N., Bobadilla, L., Michael, P., Saturn, S. R., & Portner, M. (2023) · Aggression and Violent Behavior · doi:10.1016/j.avb.2023.101828 · Cited by 11 · see citing works
van Strien, T., Beijers, R., Smeekens, S., & Winkens, L. H. H. (2018) · Appetite · doi:10.1016/j.appet.2018.10.006 · Cited by 11 · see citing works
Koh, M. J., Kim, W., Kang, J. I., Namkoong, K., & Kim, S. J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0143168 · Cited by 10 · see citing works
Skotalczyk, M., Dąbrowska, K. A., Smorońska-Rypel, J., Wilczyński, K. M., & Janas-Kozik, M. H. (2024) · European Journal of Investigation in Health Psychology and Education · doi:10.3390/ejihpe14030044 · Cited by 10 · see citing works
Does oxytocin shield against negative effects of ostracism? A replication and extension
Pfundmair, M., & Echterhoff, G. (2021) · Biological Psychology · doi:10.1016/j.biopsycho.2021.108128 · Cited by 9 · see citing works
Oxytocin and cardiometabolic interoception: Knowing oneself affects ingestive and social behaviors
Smith, J. A., Eikenberry, S. A., Scott, K. A., Baumer-Harrison, C., de Lartigue, G., de Kloet, A. D., & Krause, E. G. (2022) · Appetite · doi:10.1016/j.appet.2022.106054 · Cited by 8 · see citing works
How Closely Related Are Parent and Child Reports of Child Alexithymia?
Lampi, A. J., Jaswal, V. K., & Evans, T. M. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.588001 · Cited by 9 · see citing works
Zimmermann, K. M., Schmidt, K. D., Gronow, F., Sommer, J. B., Leweke, F., & Jansen, A. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118223 · Cited by 8 · see citing works
Lin, C., Zhuo, S., Zheng, Q., Li, X., & Peng, W. (2023) · Physiology & Behavior · doi:10.1016/j.physbeh.2023.114266 · Cited by 7 · see citing works
Genetic Factors and Endocrine and Immune System Functioning Associated with Alexithymia
Kano, M., Grabe, H. J., & Terock, J. (2018) · Cambridge University Press eBooks · doi:10.1017/9781108241595.017 · Cited by 7 · see citing works
Psychoendocrinologie sociale de l’ocytocine : revue d’une littérature en pleine expansion
Lane, A., Luminet, O., & Mikolajczak, M. (2013) · L’Année psychologique · doi:10.4074/s0003503313002066 · Cited by 11 · see citing works
van Sleeuwen, C., van Zuiden, M., Koch, S. B. J., Frijling, J. L., Veltman, D. J., Olff, M., & Nawijn, L. (2023) · European Journal of Psychotraumatology · doi:10.1080/20008066.2023.2281187 · Cited by 6 · see citing works
Gandolphe, M., & Nandrino, J. (2012) · Psychologie Française · doi:10.1016/j.psfr.2012.09.002 · Cited by 5 · see citing works
Caine, J. A., Klein, B., & Edwards, S. L. (2020) · JMIR Research Protocols · doi:10.2196/24543 · Cited by 6 · see citing works
Genetically based correlates of serum oxytocin and testosterone in autism and schizotypy
Crespi, B. J., & Hurd, P. L. (2015) · Personality and Individual Differences · doi:10.1016/j.paid.2015.01.052 · Cited by 4 · see citing works
The relationship between alexithymia and hypnotic susceptibility: A review of the literature
Költő, A., & Bányai, E. I. (2014) · Mentálhigiéné és Pszichoszomatika · doi:10.1556/mental.15.2014.004 · Cited by 3 · see citing works
Effects of Oxytocin on Agency in Anxiously Attached Individuals, a Replication and Extension
Bartz, J. A., Klein, W., & Gregory, A. J. P. (2025) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsaf049 · Cited by 3 · see citing works
Verbeke, W., & Pozharliev, R. (2016) · International Journal of Marketing Studies · doi:10.5539/ijms.v8n4p1 · Cited by 3 · see citing works
Human, L. J., Thorson, K. R., Woolley, J. D., & Mendes, W. B. (2017) · Hormones and Behavior · doi:10.1016/j.yhbeh.2017.03.002 · Cited by 3 · see citing works
Short-term impact of alcohol detoxification on facial emotions recognition
Frileux, S., Dubertret, C., & Strat, Y. L. (2020) · L Encéphale · doi:10.1016/j.encep.2020.04.019 · Cited by 3 · see citing works
Vieira, K. R., Poltronieri, B. C., Panizzutti, R., & Velasques, B. (2026) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.70126 · Cited by 2 · see citing works
Incomprehensible emotions – a neuropsychological perspective on alexithymia
Halicka, M., & Herzog-Krzywoszańska, R. (2016) · Neuropsychiatria i Neuropsychologia · doi:10.5114/nan.2016.62252 · Cited by 2 · see citing works
Neurochemistry of Prosocial Decision Making
Declerck, C. H., & Boone, C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801303-8.00003-3 · Cited by 2 · see citing works
RECALLED PARENTAL REARING STYLE AND DIMENSIONS OF HYPNOTIC RESPONSE
Költő, A., Józsa, E., & Bányai, E. I. (2019) · International Journal of Clinical and Experimental Hypnosis · doi:10.1080/00207144.2019.1580968 · Cited by 2 · see citing works
Kokubun, K., Nemoto, K., Okamoto, M., & Yamakawa, Y. (2025) · Brain and Cognition · doi:10.1016/j.bandc.2025.106381 · Cited by 1 · see citing works
Feeser, M. (2015) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-7212
The Influence of Oxytocin on Older Adults’ Emotion Processing
Campbell, A. (2015) · Otago University Research Archive (University of Otago)
Weigand, A. (2013) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-5014
Oksitosiini, suojelumotivaatio ja aivojen frontaaliasymmetria pienten lasten äideillä
Lappalainen, H. (2015) · Tampere University Institutional Repository (Tampere University)
Personality Disorders: A Short Review
Lorenzini, N., & Fonagy, P. (2013)
The relationship between oxytocin pathway genes and personality traits and psychosis characteristics
Haram, M. (2017) · NORA - Norwegian Open Research Archives
- Authors
- Luminet, O., Grynberg, D., Ruzette, N., & Mikolajczak, M.
- Affiliations
- Fund for Scientific Research (BE)
- UCLouvain (BE)
- Corresponding author
- Luminet, Olivier
- Venue
- Biological Psychology
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 87
- Issue
- 3
- Pages
- 401-406
- ISSN
- 0301-0511 (ISSN-L)
- OpenAlex
- W2024067798
- Cited by
- 107
- References
- 70
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 2 · 2023: 6 · 2022: 3 · 2021: 10 · 2020: 5 · 2019: 4 · 2018: 7 · 2017: 11 · 2016: 11 · 2015: 13 · 2014: 9 · 2013: 14 · 2012: 5
- FWCI
- 12.62
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Biological Psychology (publishedVersion)
- PubMed (publishedVersion)
- Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) (submittedVersion, other-oa)
- Funders
- Fonds De La Recherche Scientifique - FNRS
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- oxytocin, alexithymia, personality differences, social cognition, theory of mind, Reading the Mind in the Eyes Test, placebo, individual differences, social behavior
- MeSH terms
- Affective Symptoms, Emotions, Facial Expression, Humans, Male, Oxytocin, Personality, Social Behavior, Social Perception, Recognition, Psychology, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review