Cited by 107Neuroendocrine regulation and behaviorAction Observation and SynchronizationPsychosomatic Disorders and Their Treatments

Personality-dependent effects of oxytocin: greater social benefits for high alexithymia scorers

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Luminet, Olivier, Grynberg, Delphine, Ruzette, Nicolas, Mikolajczak, Moïra·2011·Biological Psychology

Abstract

Originally known for its role in labor and lactation, oxytocin (OT) has recently been shown to facilitate social behaviour by improving socio-emotional abilities. However, whether OT is equally beneficial to all people, or whether is it particularly beneficial to less emotionally/socially competent (i.e., high alexithymia) individuals it is not yet known. We investigated the effects of OT on individuals of varying socio-emotional ability by randomly assigning sixty male students to receive either oxytocin (OT) or a placebo (PL), and had them perform the Reading the Mind in the Eyes test (RMET). Results showed that whereas the performance of lower alexithymia individuals was equally good in both OT and PL conditions, the performance of higher alexithymia people was better under OT than PL. These results suggest that the effects of OT are not only context-dependent-as recently shown-but also personality dependent. They also provide new insights into the remediation of socio-emotional deficits.

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Crossref · 10.1016/j.biopsycho.2011.05.005

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  • Enhanced prosocial effects of intranasally administered OT are especially pronounced for individuals with socio-emotional deficits, such as Asperger syndrome or high alexithymia.

    “It appears that the enhanced prosocial effects of intranasally administered OT are especially pronounced for individuals suffering from socio-emotional deficits, as is the case for individuals with Asperger syndrome (Andari et al., 2010) or high alexithymia (Luminet et al., 2011).”

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Authors
Luminet, O., Grynberg, D., Ruzette, N., & Mikolajczak, M.
Affiliations
  • Fund for Scientific Research (BE)
  • UCLouvain (BE)
Corresponding author
Luminet, Olivier
Venue
Biological Psychology
Publisher
Elsevier BV
Published
2011-07
Volume
87
Issue
3
Pages
401-406
ISSN
0301-0511 (ISSN-L)
OpenAlex
W2024067798
Cited by
107
References
70
Citations by year
2026: 3 · 2025: 3 · 2024: 2 · 2023: 6 · 2022: 3 · 2021: 10 · 2020: 5 · 2019: 4 · 2018: 7 · 2017: 11 · 2016: 11 · 2015: 13 · 2014: 9 · 2013: 14 · 2012: 5
FWCI
12.62
Type
journal article
Language
en
Open access
Locations
  • Biological Psychology (publishedVersion)
  • PubMed (publishedVersion)
  • Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) (submittedVersion, other-oa)
Funders
Fonds De La Recherche Scientifique - FNRS
Topics
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords
oxytocin, alexithymia, personality differences, social cognition, theory of mind, Reading the Mind in the Eyes Test, placebo, individual differences, social behavior
MeSH terms
Affective Symptoms, Emotions, Facial Expression, Humans, Male, Oxytocin, Personality, Social Behavior, Social Perception, Recognition, Psychology, Young Adult

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