Cited by 48Biofield Effects and BiophysicsMicrotubule and mitosis dynamicsCellular Mechanics and Interactions

Biological wires, communication systems, and implications for disease

Friesen, Douglas E., Craddock, Travis J.A., Kalra, Aarat P., Tuszynski, Jack A.·2015·Biosystems

Abstract

Microtubules, actin, and collagen are macromolecular structures that compose a large percentage of the proteins in the human body, helping form and maintain both intracellular and extracellular structure. They are biological wires and are structurally connected through various other proteins. Microtubules (MTs) have been theorized to be involved in classical and quantum information processing, and evidence continues to suggest possible semiconduction through MTs. The previous Dendritic Cytoskeleton Information Processing Model has hypothesized how MTs and actin form a communication network in neurons. Here, we review information transfer possibilities involving MTs, actin, and collagen, and the evidence of an organism-wide high-speed communication network that may regulate morphogenesis and cellular proliferation. The direct and indirect evidence in support of this hypothesis, and implications for chronic diseases such as cancer and neurodegenerative diseases are discussed.

Integrity signals

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Crossref · 10.1016/j.biosystems.2014.10.006

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Authors
Friesen, D. E., Craddock, T. J. A., Kalra, A. P., & Tuszynski, J. A.
Affiliations
  • University of Alberta (CA)
  • Nova Southeastern University (US)
  • Dayalbagh Educational Institute (IN)
Venue
Biosystems
Publisher
Elsevier BV
Published
2015-01
Volume
127
Pages
14-27
ISSN
0303-2647 (ISSN-L)
OpenAlex
W2028671607
Cited by
48
References
204
Citations by year
2026: 3 · 2025: 2 · 2024: 4 · 2023: 1 · 2022: 6 · 2021: 4 · 2020: 7 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 7 · 2015: 5
FWCI
0.55
Type
journal article
Language
en
Open access
closed
Locations
  • Biosystems (publishedVersion)
  • PubMed (publishedVersion)
  • NSUWorks (Nova Southeastern University) (submittedVersion)
Funders
  • Nova Southeastern University’s Center for Psychological Studies and Institute for Neuro-Immune Medicine
  • NSERC (Canada)
Topics
  • Health Sciences › Medicine › Physiology › Biofield Effects and Biophysics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Microtubule and mitosis dynamics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
Keywords
microtubules, actin, collagen, quantum information processing, morphogenesis, cell proliferation, cancer, neurodegenerative diseases
MeSH terms
Actins, Cell Communication, Collagen, Electric Conductivity, Extracellular Matrix, Humans, Microtubules, Models, Biological, Signal Transduction, Gap Junctions

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