The DOI matches its Crossref record; 160 of the 164 references it cites were found in a registry or an index.
Noradrenergic modulation of arousal
Open accessAbstract
Through a highly divergent efferent projection system, the locus coeruleus-noradrenergic system supplies norepinephrine throughout the central nervous system. State-dependent neuronal discharge activity of locus coeruleus neurons has long-suggested a role of this system in the induction of an alert waking state. More recent work supports this hypothesis, demonstrating robust wake-promoting actions of the locus coeruleus-noradrenergic system. Norepinephrine enhances arousal, in part, via actions of beta- and alpha1-receptors located within multiple subcortical structures, including the general regions of the medial septal area and the medial preoptic areas. Recent anatomical studies suggest that arousal-enhancing actions of norepinephrine are not limited to the locus coeruleus system and likely include the A1 and A2 noradrenergic cell groups. Thus, noradrenergic modulation of arousal state involves multiple noradrenergic systems acting within multiple subcortical regions. Pharmacological studies indicate that the combined actions of these systems are necessary for the sustained maintenance of arousal levels associated with spontaneous waking. Enhanced arousal state is a prominent aspect of both stress and psychostimulant drug action and evidence indicates that noradrenergic systems likely play an important role in both stress-related and psychostimulant-induced arousal. These and other observations suggest that the dysregulation of noradrenergic neurotransmission could well co…
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Multivariate pattern analyses have provided robust evidence that TMR actually induces a behaviorally relevant reactivation of cue-associated target information.”
From Sleep—A brain-state serving systems memory consolidation (2023) · cites this paper as [117]
In the citing paper
“The beneficial effect of TMR during non-REM sleep on memory performance is well established across a variety of memory domains, 115 including visuospatial 116-119 and verbal 120,121 declarative memory as well as motor learning.”
From Sleep—A brain-state serving systems memory consolidation (2023) · cites this paper as [117]
In the citing paper
“timing of cue delivery in relation to SOs, 129 spindles, or spindle refractory periods, respectively, 116,117,127 or the phase-coupling of spindles to the SO peak or trough 125 may substantially affect the effect of TMR on memory performance.”
From Sleep—A brain-state serving systems memory consolidation (2023) · cites this paper as [117]
In the citing paper
“Evidence for category-specific reactivations was strongest when cue delivery was accompanied by increased spindle activity and, moreover, predicted the TMR-induced gain in memory.”
From Sleep—A brain-state serving systems memory consolidation (2023) · cites this paper as [117]
In the citing paper
“It is associated with increased SO power, amplitude and density, 120,125,128 increased spindle power and density, 116,117,120,128 as well as improved SO-spindle coupling, 120 and these characteristics are often associated with the TMRinduced memory advantage.”
From Sleep—A brain-state serving systems memory consolidation (2023) · cites this paper as [117]
Citations
Cites
The relation of strength of stimulus to rapidity of habit formation
Yerkes, R. M., & Dodson, J. D. (1908) · Journal of Comparative Neurology and Psychology · doi:10.1002/cne.920180503 · Cited by 6,911
Aston-Jones, G., & Cohen, J. D. (2005) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.28.061604.135709 · Cited by 4,472
Brain stem reticular formation and activation of the EEG
Moruzzi, G., & Magoun, H. W. (1949) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(49)90219-9 · Cited by 4,307
Memory - A century of consolidation
McGaugh, J. L. (2000) · Science · doi:10.1126/science.287.5451.248 · Cited by 4,250
Hypothalamic regulation of sleep and circadian rhythms
Saper, C. B., Scammell, T. E., & Lu, J. (2005) · Nature · doi:10.1038/nature04284 · Cited by 2,804
Berridge, C. W., & Waterhouse, B. D. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(03)00143-7 · Cited by 2,529
Self-citationTHE GENERAL ADAPTATION SYNDROME AND THE DISEASES OF ADAPTATION1
Selye, H. (1946) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-6-2-117 · Cited by 2,296
Aston-Jones, G., & Bloom, F. (1981) · The Journal of Neuroscience · doi:10.1523/jneurosci.01-08-00876.1981 · Cited by 1,960
Nucleus locus ceruleus: new evidence of anatomical and physiological specificity
Foote, S. L., Bloom, F. E., & Aston-Jones, G. (1983) · Physiological Reviews · doi:10.1152/physrev.1983.63.3.844 · Cited by 1,901
Swanson, L. W., & Cowan, W. M. (1977) · The Journal of Comparative Neurology · doi:10.1002/cne.901720104 · Cited by 1,592
Research works printed but not linked: 2
- Berridge, 2007, Norepinephrine acts within the lateral hypothalamus to promote waking: relevance to psychostimulant-induced arousal, Soc. Neurosci. Abst., 736.21
- Bremer, 1937, Cerebral activity during sleep and narcosis: contribution to the study of the mechanisms of sleep, Bull. Acad. R. Med. Belg., 4, 240
Cited by
Sorted by citations
Chronic stress, drug use, and vulnerability to addiction
Sinha, R. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1441.030 · Cited by 1,904
Orienting and reorienting: the locus coeruleus mediates cognition through arousal
Sara, S. J., & Bouret, S. (2012) · Neuron · doi:10.1016/j.neuron.2012.09.011 · Cited by 1,056
Rajmohan, R., & Reddy, P. H. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-160612 · Cited by 730
Neuromodulation of Brain States
Lee, S., & Dan, Y. (2012) · Neuron · doi:10.1016/j.neuron.2012.09.012 · Cited by 697
Metabolism and functions of copper in brain
Scheiber, I. F., Mercer, J. F. B., & Dringen, R. (2014) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2014.01.002 · Cited by 524
Alnæs, D., Sneve, M. H., Espeseth, T., Endestad, T., van de Pavert, S. H., & Laeng, B. (2014) · Journal of Vision · doi:10.1167/14.4.1 · Cited by 538
Plasticity of Cortical Excitatory-Inhibitory Balance
Froemke, R. C. (2015) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-071714-034002 · Cited by 458
Sleep—A brain-state serving systems memory consolidation
Brodt, S., Inostroza, M., Niethard, N., & Born, J. (2023) · Neuron · doi:10.1016/j.neuron.2023.03.005 · Cited by 343
Benarroch, E. E. (2009) · Neurology · doi:10.1212/wnl.0b013e3181c2937c · Cited by 317
Current perspectives of the roles of the central norepinephrine system in anxiety and depression
Goddard, A. W., Ball, S. G., Martinez, J. M., Robinson, M. J., Yang, C. R., Russell, J. M., & Shekhar, A. (2009) · Depression and Anxiety · doi:10.1002/da.20642 · Cited by 332
Neuroanatomy of the extended circadian rhythm system
Morin, L. P. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.06.026 · Cited by 326
Stahl, S. M., Sommer, B., & Allers, K. A. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2010.02032.x · Cited by 294
A gut microbial factor modulates locomotor behaviour in Drosophila
Schretter, C. E., Vielmetter, J., Bartos, I., Marka, Z., Marka, S., Argade, S., & Mazmanian, S. K. (2018) · Nature · doi:10.1038/s41586-018-0634-9 · Cited by 289
Locus coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep
Hayat, H., Regev, N., Matosevich, N., Sales, A. C., Paredes-Rodriguez, E., Krom, A. J., Bergman, L., Li, Y., Lavigne, M., Kremer, E. J., et al. (2020) · Science Advances · doi:10.1126/sciadv.aaz4232 · Cited by 268
Noradrenergic circuit control of non-REM sleep substates
Osorio-Forero, A., Cardis, R., Vantomme, G., Guillaume-Gentil, A., Katsioudi, G., Devenoges, C., Fernandez, L. M. J., & Lüthi, A. (2021) · Current Biology · doi:10.1016/j.cub.2021.09.041 · Cited by 230
Coordinated forms of noradrenergic plasticity in the locus coeruleus and primary auditory cortex
Martins, A. R. O., & Froemke, R. C. (2015) · Nature Neuroscience · doi:10.1038/nn.4090 · Cited by 233
Dopamine and Noradrenaline in the Brain; Overlapping or Dissociate Functions?
Ranjbar‐Slamloo, Y., & Fazlali, Z. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00334 · Cited by 241
The vigilance regulation model of affective disorders and ADHD
Hegerl, U., & Hensch, T. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.10.008 · Cited by 212
Optogenetic dissection of medial prefrontal cortex circuitry
Riga, D., Matos, M. R., Glas, A., Smit, A. B., Spijker, S., & Van den Oever, M. C. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00230 · Cited by 208
Impairment of Attentional Networks after 1 Night of Sleep Deprivation
Tomasi, D. G., Wang, R. L., Telang, F., Boronikolas, V., Jayne, M. C., Wang, G., Fowler, J. S., & Volkow, N. D. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn073 · Cited by 201
Stress Potentiates Early and Attenuates Late Stages of Visual Processing
Shackman, A. J., Maxwell, J. S., McMenamin, B. W., Greischar, L. L., & Davidson, R. J. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.3384-10.2011 · Cited by 191
Twenty-Five Lessons from Computational Neuromodulation
Dayan, P. (2012) · Neuron · doi:10.1016/j.neuron.2012.09.027 · Cited by 190
Beyond the Cholinergic Hypothesis: Do Current Drugs Work in Alzheimer's Disease?
Martorana, A., Esposito, Z., & Koch, G. (2010) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2010.00175.x · Cited by 174
Breton‐Provencher, V., Drummond, G. T., & Sur, M. (2021) · Frontiers in Neural Circuits · doi:10.3389/fncir.2021.638007 · Cited by 182
Hypocretin/orexin in arousal and stress
Berridge, C. W., España, R. A., & Vittoz, N. M. (2009) · Brain Research · doi:10.1016/j.brainres.2009.09.019 · Cited by 180
Self-citationOnose, G., Grozea, C., Anghelescu, A., Daia, C. O., Sinescu, C. J., Ciurea, A. V., Spircu, T., Mirea, A., Andone, I., Spînu, A., et al. (2012) · Spinal Cord · doi:10.1038/sc.2012.14 · Cited by 175
Good night and good luck: Norepinephrine in sleep pharmacology
Mitchell, H. A., & Weinshenker, D. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.10.004 · Cited by 168
Consensus guideline for the diagnosis and treatment of tetrahydrobiopterin (BH4) deficiencies
on behalf of the International Working Group on Neurotransmitter related Disorders (iNTD), Opladen, T., López‐Laso, E., Cortès‐Saladelafont, E., Pearson, T. S., Hs, S., Yıldız, Y., Assmann, B. E., Kurian, M. A., Leuzzi, V., et al. (2020) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-020-01379-8 · Cited by 165
Berridge, C. W., & Devilbiss, D. M. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.06.023 · Cited by 160
Self-citationHagena, H., Hansen, N., & Manahan‐Vaughan, D. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhv330 · Cited by 174
A right hemisphere role in cognitive reserve
Robertson, I. H. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.11.028 · Cited by 155
Genetic analysis of sleepPreprint
Crocker, A. J., & Sehgal, A. (2010) · Genes & Development · doi:10.1101/gad.1913110 · Cited by 156
Brain and gut CRF signaling: biological actions and role in the gastrointestinal tract
Tache, Y., Larauche, M., Yuan, P.-Q., & Million, M. (2018) · Current Molecular Pharmacology · doi:10.2174/1874467210666170224095741 · Cited by 147
Dopaminergic and Noradrenergic Contributions to Functionality in ADHD: The Role of Methylphenidate
Engert, V., & Pruessner, J. (2008) · Current Neuropharmacology · doi:10.2174/157015908787386069 · Cited by 146
Chandler, D. J., Waterhouse, B. D., & Gao, W. (2014) · Frontiers in Neural Circuits · doi:10.3389/fncir.2014.00053 · Cited by 143
Hilbert, K., Lueken, U., & Beesdo‐Baum, K. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.01.022 · Cited by 153
Working memory performance after acute exposure to the cold pressor stress in healthy volunteers
Dunčko, R., Johnson, L. L., Merikangas, K. R., & Grillon, C. (2009) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2009.01.006 · Cited by 137
Robust Reproducible Resting State Networks in the Awake Rodent Brain
Becerra, L. R., Pendse, G., Chang, P.-C., Bishop, J. H., & Borsook, D. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025701 · Cited by 136
Autonomic dysfunction in primary sleep disorders
Miglis, M. G. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2015.10.001 · Cited by 133
Osorio-Forero, A., Foustoukos, G., Cardis, R., Cherrad, N., Devenoges, C., Fernandez, L. M. J., & Lüthi, A. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01822-0 · Cited by 175
Real-world stress resilience is associated with the responsivity of the locus coeruleus
Grueschow, M., Stenz, N., Thörn, H., Ehlert, U., Breckwoldt, J., Brodmann Maeder, M., Exadaktylos, A. K., Bingisser, R., Ruff, C. C., & Kleim, B. (2021) · Nature Communications · doi:10.1038/s41467-021-22509-1 · Cited by 116
Autism, fever, epigenetics and the locus coeruleus
Mehler, M. F., & Purpura, D. P. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2008.11.001 · Cited by 115
The Pupil as Marker of Cognitive Processes
Einhäuser, W. (2016) · Cognitive science and technology · doi:10.1007/978-981-10-0213-7_7 · Cited by 117
Deconstructing arousal into wakeful, autonomic and affective varieties
Satpute, A. B., Kragel, P. A., Barrett, L. F., Wager, T. D., & Bianciardi, M. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.01.042 · Cited by 118
Is lactate a volume transmitter of metabolic states of the brain?
Bergersen, L. H., & GJEDDE, A. H. (2012) · Frontiers in Neuroenergetics · doi:10.3389/fnene.2012.00005 · Cited by 111
Pathophysiology of tic disorders
Yael, D., Vinner, E., & Bar‐Gad, I. (2015) · Movement Disorders · doi:10.1002/mds.26304 · Cited by 110
Taché, Y., & Million, M. (2015) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm14162 · Cited by 102
Modulation of physiological reflexes by pain: role of the locus coeruleus
Szabadi, E. (2012) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2012.00094 · Cited by 111
Arousal From Sleep and Sympathetic Excitation During Wakefulness
Taylor, K. S., Murai, H., Millar, P. J., Haruki, N., Kimmerly, D. S., Morris, B. L., TOMLINSON, G. A., Bradley, T. D., & Floras, J. S. (2016) · Hypertension · doi:10.1161/hypertensionaha.116.08212 · Cited by 102
Population Response Profiles in Early Visual Cortex Are Biased in Favor of More Valuable Stimuli
Serences, J. T., & Saproo, S. (2010) · Journal of Neurophysiology · doi:10.1152/jn.01090.2009 · Cited by 100
Catecholamines alter the intrinsic variability of cortical population activity and perception
Pfeffer, T. A., Avrămiea, A.-E., Nolte, G., Engel, A. K., Linkenkaer‐Hansen, K., & Donner, T. H. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2003453 · Cited by 98
Tau-driven degeneration of sleep- and wake-regulating neurons in Alzheimer’s disease
Lew, C. H., Petersen, C., Neylan, T. C., & Grinberg, L. T. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101541 · Cited by 100
Gibbs, M. E., Hutchinson, D. S., & Summers, R. J. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.07.052 · Cited by 98
Marzo, A., Totah, N. K. B., Neves, R. M., Logothetis, N. K., & Eschenko, O. (2014) · Journal of Neurophysiology · doi:10.1152/jn.00920.2013 · Cited by 90
Regulation of neuron-astrocyte metabolic coupling across the sleep-wake cycle
Petit, J.-M., & Magistretti, P. J. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.12.007 · Cited by 92
Cicco, V. D., Fantozzi, M. P. T., Cataldo, E., Barresi, M., Bruschini, L., Faraguna, U., & Manzoni, D. (2018) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2017.00130 · Cited by 95
Baladi, M. G., Forster, M. J., Gatch, M. B., Mailman, R. B., Hyman, D. L., Carter, L. P., & Janowsky, A. J. (2018) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.118.248120 · Cited by 92
A Rare Mutation of β1-Adrenergic Receptor Affects Sleep/Wake Behaviors
Shi, G., Xing, L., Wu, D., Bhattacharyya, B. J., Jones, C. R., McMahon, T., Chong, S. Y. C., Chen, J., Coppola, G., Geschwind, D. H., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.07.026 · Cited by 90
Wang, X., Piñol, R. A., Byrne, P., & Mendelowitz, D. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.5093-13.2014 · Cited by 89
Collins, L. N., Francis, J., Emanuel, B., & McCormick, D. A. (2023) · eLife · doi:10.7554/elife.81826 · Cited by 87
Kim, H., Jung, H. R., Kim, J. B., & Kim, D. (2022) · Journal of Clinical Neurology · doi:10.3988/jcn.2022.18.2.140 · Cited by 93
Role of the locus coeruleus and basal forebrain in arousal and attention
Maness, E. B., Burk, J. A., McKenna, J. T., Schiffino, F. L., Strecker, R. E., & McCoy, J. G. (2022) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2022.07.014 · Cited by 92
Sex-dependent neurotransmitter level changes in brains of Toxoplasma gondii infected mice
Gatkowska, J. M., Wieczorek, M., Dziadek, B. R., Dzitko, K., & Długońska, H. (2012) · Experimental Parasitology · doi:10.1016/j.exppara.2012.10.005 · Cited by 84
Rodent models of insomnia: A review of experimental procedures that induce sleep disturbances
Revel, F. G., Gottowik, J., Gatti, S., Wettstein, J. G., & Moreau, J. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.03.002 · Cited by 90
Keute, M., Demirezen, M., Graf, A., Mueller, N. G., & Zaehle, T. (2019) · Scientific Reports · doi:10.1038/s41598-019-47961-4 · Cited by 82
Anxiety: An ignored aspect of Parkinson's disease lacking attention.
Khatri, D., Choudhary, M., Sood, A., & Singh, S. B. (2020) · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · doi:10.1016/j.biopha.2020.110776 · Cited by 65
Prefrontal modulation of anxiety through a lens of noradrenergic signaling
Bouras, N. N., Mack, N. R., & Gao, W. (2023) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2023.1173326 · Cited by 88
Magzal, F., Even, C., Haimov, I., Agmon, M., Asraf, K., Shochat, T., & Tamir, S. (2021) · Scientific Reports · doi:10.1038/s41598-021-83389-5 · Cited by 82
Neuroendocrine control of seasonal plasticity in the auditory and vocal systems of fish
Forlano, P. M., Sisneros, J. A., Rohmann, K. N., & Bass, A. H. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.08.002 · Cited by 74
Wei, Y., Xu, J., Miao, S., Wei, K., Peng, L., Wang, Y., & Wei, X. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2048291 · Cited by 73
Negative Emotion in Music: What is the Attraction? A Qualitative Study
Garrido, S., & Schubert, E. (2011) · Empirical Musicology Review · doi:10.18061/1811/52950 · Cited by 77
Linson, A., Parr, T., & Friston, K. J. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112421 · Cited by 76
Environmental complexity buffers against stress-induced negative judgement bias in female chickens
Zidar, J., Campderrich, I., Jansson, E., Wichman, A., Winberg, S., Keeling, L. J., & Løvlie, H. (2018) · Scientific Reports · doi:10.1038/s41598-018-23545-6 · Cited by 73
Optimality and Robustness of a Biophysical Decision-Making Model under Norepinephrine Modulation
Eckhoff, P. A., Wong‐Lin, K., & Holmes, P. J. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5024-08.2009 · Cited by 67
Allers, K. A., Dremencov, E., Ceci, A., Flik, G., Ferger, B., Cremers, T. I. F. H., Ittrich, C., & Sommer, B. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2010.01763.x · Cited by 70
Pharmacological animal models of Tourette syndrome
Bronfeld, M., Israelashvili, M., & Bar‐Gad, I. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.09.010 · Cited by 70
Involvement of Tuberomamillary Histaminergic Neurons in Isoflurane Anesthesia
Luo, T., & Leung, L.-W. S. (2011) · Anesthesiology · doi:10.1097/aln.0b013e3182207655 · Cited by 67
Serotonergic and Noradrenergic Modulation of Emotion Processing by Single Dose Antidepressants
Brühl, A. B., Kaffenberger, T., & Herwig, U. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.159 · Cited by 66
Assessment of Wakefulness and Brain Arousal Regulation in Psychiatric Research
Sander, C., Hensch, T., Wittekind, D. A., Böttger, D., & Hegerl, U. (2015) · Neuropsychobiology · doi:10.1159/000439384 · Cited by 65
Eyes on me: an fMRI study of the effects of social gaze on action control
Schilbach, L., Eickhoff, S. B., Cieslik, E. C., Shah, N. J., Fink, G. R., & Vogeley, K. T. (2010) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsq067 · Cited by 60
Background luminance effects on pupil size associated with emotion and saccade preparation
Cherng, Y., Baird, T., Chen, J., & Wang, C. (2020) · Scientific Reports · doi:10.1038/s41598-020-72954-z · Cited by 60
Hu, F. Y., Hanna, G. M., Han, W., Mardini, F., Thomas, S. A., Wyner, A. J., & Kelz, M. B. (2012) · Anesthesiology · doi:10.1097/aln.0b013e3182700ab9 · Cited by 58
Neurobiological mechanisms that contribute to stress-related cocaine use
Mantsch, J. R., Vranjkovic, O., Twining, R. C., Gasser, P. J., McReynolds, J. R., & Blacktop, J. M. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.07.021 · Cited by 63
Noradrenergic and cholinergic modulation of late ERP responses to deviant stimuli
Brown, S. B. R. E., van der Wee, N. J. A., van Noorden, M. S., Giltay, E. J., & Nieuwenhuis, S. (2015) · Psychophysiology · doi:10.1111/psyp.12544 · Cited by 59
What birdsong can teach us about the central noradrenergic system
Castelino, C. B., & Schmidt, M. F. (2009) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2009.08.003 · Cited by 56
Corticotropin-releasing factor receptor type 1 and type 2 interaction in irritable bowel syndrome
Nozu, T., & Okumura, T. (2015) · Journal of Gastroenterology · doi:10.1007/s00535-015-1086-8 · Cited by 59
Discrete Forebrain Neuronal Networks Supporting Noradrenergic Regulation of Sensorimotor Gating
Alsene, K. M., Rajbhandari, A. K., Ramaker, M. J., & Bakshi, V. P. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.238 · Cited by 55
Role of coerulean noradrenergic neurones in general anaesthesia in rats
Kushikata, T., Yoshida, H., Kudo, M., Kudo, T., Kudo, T., & Hirota, K. (2011) · British Journal of Anaesthesia · doi:10.1093/bja/aer303 · Cited by 54
Pharmacological evidence for the implication of noradrenaline in effort
Borderies, N., Mattioni, J., Bornert, P., Gilardeau, S., & Bouret, S. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000793 · Cited by 49
Loss of Gnas Imprinting Differentially Affects REM/NREM Sleep and Cognition in Mice
Lassi, G., Ball, S. T., Maggi, S., Colonna, G., Nieus, T. R., Cero, C., Bartolomucci, A., Peters, J., & Tucci, V. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002706 · Cited by 53
Effect of arousal on sympathetic overactivity in patients with obstructive sleep apnea
Kim, J. B., Seo, B. S., & Kim, J. H. (2019) · Sleep Medicine · doi:10.1016/j.sleep.2019.01.044 · Cited by 53
Norepinephrine in the brain is associated with aversion to financial loss
Takahashi, H., Fujie, S., Camerer, C., Arakawa, R., Takano, H., Kodaka, F., Matsui, H., Ideno, T., Okubo, S., Takemura, K., et al. (2013) · Molecular Psychiatry · doi:10.1038/mp.2012.7 · Cited by 52
Aimon, S., Cheng, K. Y., Gjorgjieva, J., & Kadow, I. C. G. (2023) · eLife · doi:10.7554/elife.85202 · Cited by 52
Neurotransmitter Systems in a Mild Blast Traumatic Brain Injury Model: Catecholamines and Serotonin
Kawa, L., Arborelius, U. P., Yoshitake, T., Kehr, J., Hökfelt, T. G. M., Risling, M., & Agoston, D. V. (2014) · Journal of Neurotrauma · doi:10.1089/neu.2014.3669 · Cited by 48
Xiang, L., Harel, A., Gao, H., Pickering, A. E., Sara, S. J., & Wiener, S. I. (2019) · Scientific Reports · doi:10.1038/s41598-018-37227-w · Cited by 46
Chen, L., McKenna, J. T., Bolortuya, Y., Winston, S. H., Thakkar, M. M., Basheer, R., Brown, R. E., & McCarley, R. W. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07401.x · Cited by 49
Relationship between obsessive compulsive disorder and cortisol: Systematic review and meta-analysis
Sousa-Lima, J., Moreira, P. S., Raposo-Lima, C., Sousa, N., & Morgado, P. F. (2019) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2019.09.001 · Cited by 49
Richter, F., García, A. M., Rodriguez Arriagada, N., Yoris, A., Birba, A., Huepe, D., Zimmer, H., Ibáñez, A., & Sedeño, L. (2021) · Human Brain Mapping · doi:10.1002/hbm.25288 · Cited by 46
Forlano, P. M., Kim, S. D., Krzyminska, Z. M., & Sisneros, J. A. (2014) · The Journal of Comparative Neurology · doi:10.1002/cne.23596 · Cited by 45
α-Adrenergic Receptor Function, Arousal and Sleep: Mechanisms and Therapeutic Implications
Broese, M., Riemann, D. W., Hein, L., & Nissen, C. (2012) · Pharmacopsychiatry · doi:10.1055/s-0031-1299728 · Cited by 44
Metadata
- Authors
- Berridge, C. W.
- Affiliations
- University of Wisconsin–Madison (US)
- Corresponding author
- Berridge, Craig W.
- ORCID
- Berridge, Craig W.
- Venue
- Brain Research Reviews
- Publisher
- Elsevier BV
- Published
- 2008-06
- Volume
- 58
- Issue
- 1
- Pages
- 1-17
- ISSN
- 0165-0173 (ISSN-L)
- PMC
- PMC2517224
- OpenAlex
- W2060611129
- Cited by
- 368
- References
- 164
- Citations by year
- 2026: 20 · 2025: 23 · 2024: 16 · 2023: 31 · 2022: 19 · 2021: 20 · 2020: 18 · 2019: 18 · 2018: 33 · 2017: 11 · 2016: 14 · 2015: 18 · 2014: 22 · 2013: 18 · 2012: 30
- FWCI
- 0.99
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Brain Research Reviews (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (R01MH062359, MH 62359)
- National Institute on Drug Abuse (K02DA000389, Z01DA000389, R01DA010681, DA-10681)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
- Keywords
- locus coeruleus, norepinephrine, arousal, wakefulness, beta-adrenergic receptors, alpha1-adrenoceptors, medial septum, medial preoptic area, stress, psychostimulants, insomnia, stress-related disorders, noradrenergic neurotransmission
- MeSH terms
- Animals, Arousal, Humans, Locus Coeruleus, Models, Anatomic, Neural Pathways, Norepinephrine, Preoptic Area, Receptors, Adrenergic, Septum of Brain
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
