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Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response

Zhang, Kezhong, Shen, Xiaohua, Wu, Jun, Sakaki, Kenjiro, Saunders, Thomas, Rutkowski, D. Thomas, Back, Sung Hoon, Kaufman, Randal J.·2006·Cell

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Crossref · 10.1016/j.cell.2005.11.040

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7 of 7 references verified0 citation errors · 0 not checkable

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  • ATF6 and CREB3L3 are ER-resident proteins that respond to stimuli by trafficking to the Golgi where they are sequentially cleaved by S1P and S2P.

    “Activating transcription factor 6 (ATF6) and cAMP response element–binding protein (CREB) 3 family members including CREB3L3 (also called CREBH) are ER-resident proteins that respond to stimuli by trafficking to the Golgi where they are sequentially cleaved by S1P and S2P (Ye et al., 2000; Zhang et al., 2006).”

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Research works printed but not linked: 35

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