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Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response
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ATF6 and CREB3L3 are ER-resident proteins that respond to stimuli by trafficking to the Golgi where they are sequentially cleaved by S1P and S2P.
“Activating transcription factor 6 (ATF6) and cAMP response element–binding protein (CREB) 3 family members including CREB3L3 (also called CREBH) are ER-resident proteins that respond to stimuli by trafficking to the Golgi where they are sequentially cleaved by S1P and S2P (Ye et al., 2000; Zhang et al., 2006).”
From POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation (2021) · cites this paper as Zhang et al., 2006
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Metadata
- Authors
- Zhang, K., Shen, X., Wu, J., Sakaki, K., Saunders, T., Rutkowski, D. T., Back, S. H., & Kaufman, R. J.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2006-02
- Volume
- 124
- Issue
- 3
- Pages
- 587-599
- ISSN
- 0092-8674
- Cited by
- 716
- References
- 7
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 2723 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
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