Autophagy Is Activated for Cell Survival after Endoplasmic ReticulumStress

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.

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Induction of the Vitamin D Receptor Attenuates Autophagy Dysfunction-Mediated Cell Death Following Traumatic Brain Injury

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Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing

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Development by Self-Digestion

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

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Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1.

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The role of autophagy during the early neonatal starvation period

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Autophagy in Health and Disease: A Double-Edged Sword

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

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Inhibition of Macroautophagy Triggers Apoptosis

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Growth factor regulation of autophagy and cell survival in the absence of apoptosis

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α-Synuclein Is Degraded by Both Autophagy and the Proteasome

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LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

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A trip to the ER: coping with stress

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Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells

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3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

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ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeatsPreprint

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Tor, a Phosphatidylinositol Kinase Homologue, Controls Autophagy in Yeast

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Autophagy Defends Cells Against Invading Group A Streptococcus

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An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of parkin

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Orchestrating the unfolded protein response in health and disease

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ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation

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Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

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Tripartite Management of Unfolded Proteins in the Endoplasmic Reticulum

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Activation of Caspase-12, an Endoplastic Reticulum (ER) Resident Caspase, through Tumor Necrosis Factor Receptor-associated Factor 2-dependent Mechanism in Response to the ER Stress

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Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response.

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Translational control in the endoplasmic reticulum stress response

Ron, D. (2002) · Journal of Clinical Investigation · doi:10.1172/jci16784 · Cited by 778 · see citing works

Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway

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Translational control in the endoplasmic reticulum stress response

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Gene-Specific Regulation by General Translation Factors

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Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

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Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

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NAD(P)H Oxidase Nox-4 Mediates 7-Ketocholesterol-Induced Endoplasmic Reticulum Stress and Apoptosis in Human Aortic Smooth Muscle Cells

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Autophagy Is Activated by Apoptotic Signalling in Sympathetic Neurons: An Alternative Mechanism of Death Execution

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Pivotal Role of the Cell Death Factor BNIP3 in Ceramide-Induced Autophagic Cell Death in Malignant Glioma Cells

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Autophagy in neurodegenerative disease: friend, foe or turncoat?

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OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

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Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B

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Autophagy regulates the processing of amino terminal huntingtin fragments

Qin, Z. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg346 · Cited by 250 · see citing works

Characterization of an ERAD Gene as VPS30/ATG6 Reveals Two Alternative and Functionally Distinct Protein Quality Control Pathways: One for Soluble Z Variant of Human α-1 Proteinase Inhibitor (A1PiZ) and Another for Aggregates of A1PiZ

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Silver enhancement of gold antibody probes in pre-embedding electron microscopic immunocytochemistry.

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Reduction of Spermatogenesis but Not Fertility in Creb3l4-Deficient Mice

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Post-transcriptional regulation of ribosome accumulation during myoblast differentiation

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Antiviral activity of arildone on deoxyribonucleic acid and ribonucleic acid viruses

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Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) ¹

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ER stress-induced cell death mechanisms

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JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

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Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

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The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus

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Regulation of autophagy by cytoplasmic p53

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Decoding cell death signals in liver inflammation

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Endoplasmic reticulum stress signalling-from basic mechanisms to clinical applications

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Hypoxia signalling through mTOR and the unfolded protein response in cancer

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Discovery of drug mode of action and drug repositioning from transcriptional responses

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Ubiquitination and selective autophagy

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Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability.

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Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia

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A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress

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Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

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Mfn2 modulates the UPR and mitochondrial function via repression of PERK

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MAPK/JNK signalling: a potential autophagy regulation pathway

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Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells.

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Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy

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JNK signaling in cancer cell survival

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Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA

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The unfolded protein response and cellular senescence. A Review in the Theme: Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease

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Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration

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Autophagy in diabetic kidney disease: regulation, pathological role and therapeutic potential

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Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy

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Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection

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Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death

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Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice

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IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux

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Autophagy promotes necrosis in apoptosis-deficient cells in response to ER stress

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Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury

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The unfolded protein response and its relevance to connective tissue diseases

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Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease

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Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification

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Autophagy-related and autophagy-regulatory genes are induced in human muscle after ultraendurance exercise

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The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics

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Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance

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AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treating Fields (TTFields)

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Hsp90 inhibitors as senolytic drugs to extend healthy aging

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Deficiency of autophagy protein Map1-LC3b mediates IL-17-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1.

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Ca2+ Dyshomeostasis Disrupts Neuronal and Synaptic Function in Alzheimer’s Disease

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Autophagy Promotes Oligodendrocyte Survival and Function following Dysmyelination in a Long-Lived Myelin Mutant

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Targeting the unfolded protein response for disease intervention.

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mTORC2 (Rictor) in Alzheimer’s Disease and Reversal of Amyloid-β Expression-Induced Insulin Resistance and Toxicity in Rat Primary Cortical Neurons

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Endoplasmic Reticulum Stress and Tumor Microenvironment in Bladder Cancer: The Missing Link

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Asbestos-induced Disruption of Calcium Homeostasis Induces Endoplasmic Reticulum Stress in Macrophages

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Ablation of C/EBP homologous protein attenuates renal fibrosis after ureteral obstruction by reducing autophagy and microtubule disruption

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Transcription factors and cognate signalling cascades in the regulation of autophagy

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PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response

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Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress

Sundaram, A., Appathurai, S., Plumb, R., & Mariappan, M. (2018) · Molecular Biology of the Cell · doi:10.1091/mbc.e17-10-0594 · Cited by 78 · see citing works

AMPK-mTOR-ULK1/2 signaling pathway and autophagy

Li, S., Sun, H., & Sun, D. (2017) · Int J Genet · doi:10.3760/cma.j.issn.1673-4386.2017.01.007

Quantitative Measurement of Events in the Mammalian Unfolded Protein Response

Shang, J. (2011) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-385928-0.00016-x · Cited by 19 · see citing works

Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction

Alers, S., Löffler, A. S., Paasch, F., Dieterle, A. M., Keppeler, H., Lauber, K., Campbell, D. G., Fehrenbacher, B., Schaller, M., Wesselborg, S., et al. (2011) · Autophagy · doi:10.4161/auto.7.12.18027 · Cited by 138 · see citing works