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Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System
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“This pairing induces a triple-stranded R-loop formation, which in turn prompts the recruitment of Cas3, the signature protein of type I systems [42,43].”
From CRISPR-Cas: Converting A Bacterial Defence Mechanism into A State-of-the-Art Genetic Manipulation Tool (2019) · cites this paper as [42]
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Rationally engineered Cas9 nucleases with improved specificity
Slaymaker, I. M., Gao, L., Zetsche, B., Scott, D. A., Yan, W. X., & Zhang, F. (2016) · Science · doi:10.1126/science.aad5227 · Cited by 2,414
Crystal structure of Cas9 in complex with guide RNA and target DNA
Nishimasu, H., Ran, F. A., Hsu, P. D., Konermann, S., Shehata, S. I., Dohmae, N., Ishitani, R., Zhang, F., & Nureki, O. (2014) · Cell · doi:10.1016/j.cell.2014.02.001 · Cited by 2,306
DNA stretching by bacterial initiators promotes replication origin opening
Duderstadt, K. E., Chuang, K., & Berger, J. M. (2011) · Nature · doi:10.1038/nature10455 · Cited by 193
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Cited by
Sorted by citations
Loureiro, A., & da Silva, G. J. (2019) · Antibiotics · doi:10.3390/antibiotics8010018 · Cited by 129
Metadata
- Authors
- Xiao, Y., Luo, M., Hayes, R. P., Kim, J., Ng, S., Ding, F., Liao, M., & Ke, A.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2017-06
- Volume
- 170
- Issue
- 1
- Pages
- 48-60.e11
- ISSN
- 0092-8674
- PMC
- PMC5841471
- Cited by
- 208
- References
- 4
- Language
- en
- Licence
- Funders
- National Institutes of Health (GM 118174, GM116632)
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- Xiao, Y., Luo, M., Hayes, R. P., Kim, J., Ng, S., Ding, F., Liao, M., & Ke, A. (2017). Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System. Cell. https://doi.org/10.1016/j.cell.2017.06.012