The Origin and Diversification of Mitochondria

Application of Phylogenetic Networks in Evolutionary Studies

Huson, D. H., & Bryant, D. (2005) · Molecular Biology and Evolution · doi:10.1093/molbev/msj030 · Cited by 8,751 · see citing works

ER Tubules Mark Sites of Mitochondrial Division

Friedman, J. R., Lackner, L. L., West, M., DiBenedetto, J. R., Nunnari, J., & Voeltz, G. K. (2011) · Science · doi:10.1126/science.1207385 · Cited by 2,072 · see citing works

A new view of the tree of life

Hug, L. A., Baker, B. J., Anantharaman, K., Brown, C. T., Probst, A. J., Castelle, C. J., Butterfield, C. N., Hernsdorf, A. W., Amano, Y., Ise, K., et al. (2016) · Nature Microbiology · doi:10.1038/nmicrobiol.2016.48 · Cited by 2,039 · see citing works

Dynamin-related Protein Drp1 Is Required for Mitochondrial Division in Mammalian Cells

Smirnova, E., Griparić, L., Shurland, D., & van der Bliek, A. M. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.8.2245 · Cited by 1,938 · see citing works

On the origin of mitosing cells

Sagan, L. (1967) · Journal of Theoretical Biology · doi:10.1016/0022-5193(67)90079-3 · Cited by 1,870 · see citing works

The genome sequence of Rickettsia prowazekii and the origin of mitochondria

Andersson, S. G. E., Zomorodipour, A., Andersson, J. O., Sicheritz-Pontén, T., Alsmark, U. C. M., Podowski, R. M., Näslund, A. K., Eriksson, A.-S., Winkler, H. H., & Kurland, C. G. (1998) · Nature · doi:10.1038/24094 · Cited by 1,697 · see citing works

Extreme genome reduction in symbiotic bacteria

McCutcheon, J. P., & Moran, N. A. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2670 · Cited by 1,464 · see citing works

Complex archaea that bridge the gap between prokaryotes and eukaryotes

Spang, A., Saw, J. H., Jørgensen, S. L., Zaremba-Niedzwiedzka, K., Martijn, J., Lind, A. E., van Eijk, R., Schleper, C., Guy, L., & Ettema, T. J. G. (2015) · Nature · doi:10.1038/nature14447 · Cited by 1,324 · see citing works

The energetics of genome complexity.

Lane, N., & Martin, W. (2010) · Nature · doi:10.1038/nature09486 · Cited by 1,289 · see citing works

The Hydrogen Hypothesis for the First Eukaryote

Martin, W., & Müller, M. (1998) · Nature · doi:10.1038/32096 · Cited by 1,282 · see citing works

Asgard archaea illuminate the origin of eukaryotic cellular complexity

Zaremba-Niedzwiedzka, K., Caceres, E. F., Saw, J. H., Bäckström, D., Juzokaite, L., Vancaester, E., Seitz, K. W., Anantharaman, K., Starnawski, P., Kjeldsen, K. U., et al. (2017) · Nature · doi:10.1038/nature21031 · Cited by 1,226 · see citing works

ORIGIN OF EUKARYOTIC CELLS

Raven, P. H. (1971) · Evolution · doi:10.1111/j.1558-5646.1971.tb01930.x · Cited by 1,173 · see citing works

Resolving difficult phylogenetic questions: Why more sequences are not enough

Philippe, H., Brinkmann, H., Lavrov, D. V., Littlewood, D. T. J., Manuel, M., Wörheide, G., & Baurain, D. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1000602 · Cited by 1,129 · see citing works

Mitochondrial Machineries for Protein Import and Assembly

Wiedemann, N., & Pfanner, N. (2017) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060815-014352 · Cited by 894 · see citing works

Eukaryotic evolution, changes and challenges

Embley, T. M., & Martin, W. (2006) · Nature · doi:10.1038/nature04546 · Cited by 867 · see citing works

Phylogenomics of the Reproductive Parasite Wolbachia pipientis wMel: A Streamlined Genome Overrun by Mobile Genetic Elements

Wu, M., Sun, L. V., Vamathevan, J., Riegler, M., Deboy, R., Brownlie, J. C., McGraw, E. A., Martin, W., Esser, C., Ahmadinejad, N., et al. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020069 · Cited by 851 · see citing works

Biochemistry and Evolution of Anaerobic Energy Metabolism in Eukaryotes

Müller, M., Mentel, M., van Hellemond, J. J., Henze, K., Woehle, C., Gould, S. B., Yu, R.-Y., van der Giezen, M., Tielens, A. G. M., & Martin, W. F. (2012) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.05024-11 · Cited by 838 · see citing works

Origin of Eukaryotic Cells.

Raven, P. H., & Margulis, L. (1971) · Evolution · doi:10.2307/2406953 · Cited by 770 · see citing works

Molecular phylogenetics: principles and practice

Yang, Z., & Rannala, B. H. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3186 · Cited by 762 · see citing works

Structure and function of mitochondrial membrane protein complexes

Kühlbrandt, W. (2015) · BMC Biology · doi:10.1186/s12915-015-0201-x · Cited by 707 · see citing works

Mitochondrial remnant organelles of Giardia function in iron-sulphur protein maturation

Tovar, J., León-Ávila, G., Sánchez, L. B., Šuťák, R., Tachezy, J., van der Giezen, M., Hernández, M., Müller, M., & Lucocq, J. M. (2003) · Nature · doi:10.1038/nature01945 · Cited by 609 · see citing works

Mitochondrial origins.

Yang, D., Oyaizu, Y., Oyaizu, H., Olsen, G. J., & Woese, C. R. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.13.4443 · Cited by 609 · see citing works

The Mitochondrial Proteome and Human Disease

Calvo, S. E., & Mootha, V. K. (2010) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-082509-141720 · Cited by 590 · see citing works

Endosymbiotic theories for eukaryote origin

Martin, W. F., Garg, S., & Zimorski, V. (2015) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2014.0330 · Cited by 583 · see citing works

Origins of Prokaryotes, Eukaryotes, Mitochondria, and Chloroplasts

Schwartz, R. M., & Dayhoff, M. O. (1978) · Science · doi:10.1126/science.202030 · Cited by 581 · see citing works

A Eukaryote without a Mitochondrial Organelle

Karnkowska, A., Vacek, V., Zubáčová, Z., Treitli, S. C., Vargová, R., Eme, L., Novák, L., Žárský, V., Barlow, L. D., Herman, E. K., et al. (2016) · Current Biology · doi:10.1016/j.cub.2016.03.053 · Cited by 417 · see citing works

Origin and Evolution of the Mitochondrial Proteome

Kurland, C. G., & Andersson, S. G. E. (2000) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.64.4.786-820.2000 · Cited by 411 · see citing works

Iron–sulfur cluster biogenesis and trafficking in mitochondria

Braymer, J. J., & Lill, R. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.r117.787101 · Cited by 389 · see citing works

Paracoccus denitrificans and the evolutionary origin of the mitochondrion

John, P., & Whatley, F. R. (1975) · Nature · doi:10.1038/254495a0 · Cited by 382 · see citing works

On the origin of mitochondria: a genomics perspective

Andersson, G., Karlberg, O., Canbäck, B., & Kurland, C. G. (2003) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2002.1193 · Cited by 363 · see citing works

The Eukaryotic Tree of Life from a Global Phylogenomic PerspectivePreprint

Burki, F. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016147 · Cited by 360 · see citing works

Endosymbiotic origin and differential loss of eukaryotic genes

Ku, C., Sathi, S. N., Roettger, M., Sousa, F. L., Lockhart, P. J., Bryant, D., Hazkani‐Covo, E., McInerney, J. O., Landan, G., & Martin, W. F. (2015) · Nature · doi:10.1038/nature14963 · Cited by 346 · see citing works

Genomic exploration of the diversity, ecology, and evolution of the archaeal domain of life

Spang, A., Caceres, E. F., & Ettema, T. J. G. (2017) · Science · doi:10.1126/science.aaf3883 · Cited by 346 · see citing works

ER-Associated Mitochondrial Division Links the Distribution of Mitochondria and Mitochondrial DNA in Yeast

Murley, A., Lackner, L. L., Osman, C., West, M., Voeltz, G. K., Walter, P., & Nunnari, J. (2013) · eLife · doi:10.7554/elife.00422 · Cited by 326 · see citing works

Symbiosis Between Methanogenic Archaea and δ-Proteobacteria as the Origin of Eukaryotes: The Syntrophic Hypothesis

Moreira, D., & López‐García, P. (1998) · Journal of Molecular Evolution · doi:10.1007/pl00006408 · Cited by 324 · see citing works

A Genome Phylogeny for Mitochondria Among  -Proteobacteria and a Predominantly Eubacterial Ancestry of Yeast Nuclear Genes

Esser, C. (2004) · Molecular Biology and Evolution · doi:10.1093/molbev/msh160 · Cited by 324 · see citing works

Why chloroplasts and mitochondria retain their own genomes and genetic systems: Colocation for redox regulation of gene expression

Allen, J. F. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1500012112 · Cited by 309 · see citing works

Reconstructing Early Events in Eukaryotic Evolution

Roger, A. J. (1999) · The American Naturalist · doi:10.1086/303290 · Cited by 283 · see citing works

From extracellular to intracellular: the establishment of mitochondria and chloroplasts

Whatley, J. M., John, P., & Whatley, F. R. (1979) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1979.0020 · Cited by 277 · see citing works

Late acquisition of mitochondria by a host with chimaeric prokaryotic ancestry

Pittis, A. A., & Gabaldón, T. (2016) · Nature · doi:10.1038/nature16941 · Cited by 259 · see citing works

A Robust Species Tree for the Alphaproteobacteria

Williams, K. P., Sobral, B., & Dickerman, A. W. (2007) · Journal of Bacteriology · doi:10.1128/jb.00269-07 · Cited by 255 · see citing works

Strikingly Bacteria-Like and Gene-Rich Mitochondrial Genomes throughout Jakobid Protists

Burger, G., Gray, M. W., Forget, L., & Lang, B. F. (2013) · Genome Biology and Evolution · doi:10.1093/gbe/evt008 · Cited by 253 · see citing works

The Inference of Gene Trees with Species Trees

Szöllősi, G. J., Tannier, É., Daubin, V., & Boussau, B. (2014) · Systematic Biology · doi:10.1093/sysbio/syu048 · Cited by 248 · see citing works

Bacteriophage origins of mitochondrial replication and transcription proteins

Shutt, T. E., & Gray, M. W. (2005) · Trends in Genetics · doi:10.1016/j.tig.2005.11.007 · Cited by 212 · see citing works

Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex

Huynen, M. A., Mühlmeister, M., Gotthardt, K., et al. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.10.009 · Cited by 210 · see citing works

Predation and eukaryote cell origins: A coevolutionary perspective

Cavalier‐Smith, T. (2008) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2008.10.002 · Cited by 206 · see citing works

Genomic reconstruction of a novel, deeply branched sediment archaeal phylum with pathways for acetogenesis and sulfur reduction

Seitz, K. W., Lazar, C. S., Hinrichs, K., Teske, A., & Baker, B. J. (2016) · The ISME Journal · doi:10.1038/ismej.2015.233 · Cited by 202 · see citing works

Computational inference of scenarios for α-proteobacterial genome evolution

Boussau, B., Karlberg, E. O., Frank, A. C., Legault, B.-A., & Andersson, S. G. E. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400975101 · Cited by 199 · see citing works

Organelles in Blastocystis that Blur the Distinction between Mitochondria and Hydrogenosomes

Stechmann, A., Hamblin, K. A., Pérez‐Brocal, V., Gaston, D., Richmond, G. S., van der Giezen, M., Clark, C. G., & Roger, A. J. (2008) · Current Biology · doi:10.1016/j.cub.2008.03.037 · Cited by 197 · see citing works

The Dual Origin of the Yeast Mitochondrial Proteome

Karlberg, O., Canbäck, B., Kurland, C. G., & Andersson, S. G. E. (2000) · Yeast · doi:10.1002/1097-0061(20000930)17:3 · Cited by 190 · see citing works

A Proteomic Survey of Chlamydomonas reinhardtii Mitochondria Sheds New Light on the Metabolic Plasticity of the Organelle and on the Nature of the -Proteobacterial Mitochondrial Ancestor

Atteia, A., Adrait, A., Brugière, S., Tardif, M., van Lis, R., Deusch, O., Dagan, T., Kühn, L., Gontero, B., Martin, W. F., et al. (2009) · Molecular Biology and Evolution · doi:10.1093/molbev/msp068 · Cited by 185 · see citing works

Evolutionary Inference across Eukaryotes Identifies Specific Pressures Favoring Mitochondrial Gene Retention

Johnston, I. G., & Williams, B. P. (2016) · Cell Systems · doi:10.1016/j.cels.2016.01.013 · Cited by 185 · see citing works

Reconstruction of the Proto-Mitochondrial Metabolism

Gabaldón, T., & Huynen, M. A. (2003) · Science · doi:10.1126/science.1085463 · Cited by 184 · see citing works

Diversity and origins of anaerobic metabolism in mitochondria and related organelles

Stairs, C. W., Leger, M. M., & Roger, A. J. (2015) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2014.0326 · Cited by 182 · see citing works

Mosaic nature of the mitochondrial proteome: Implications for the origin and evolution of mitochondria

Gray, M. W. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1421379112 · Cited by 172 · see citing works

A comprehensive analysis of Trypanosoma brucei mitochondrial proteome

Panigrahi, A. K., Ogata, Y., Zı́ková, A., et al. (2008) · PROTEOMICS · doi:10.1002/pmic.200800477 · Cited by 171 · see citing works

An Evolutionary Network of Genes Present in the Eukaryote Common Ancestor Polls Genomes on Eukaryotic and Mitochondrial Origin

Thiergart, T., Landan, G., Schenk, M., Dagan, T., & Martin, W. F. (2012) · Genome Biology and Evolution · doi:10.1093/gbe/evs018 · Cited by 170 · see citing works

Phylogenomic evidence for a common ancestor of mitochondria and the SAR11 clade

Thrash, J. C., Boyd, A., Huggett, M. J., Grote, J., Carini, P., Yoder, R. J., Robbertse, B., Spatafora, J. W., Rappé, M. S., & Giovannoni, S. J. (2011) · Scientific Reports · doi:10.1038/srep00013 · Cited by 166 · see citing works

An integrated phylogenomic approach toward pinpointing the origin of mitochondria

Wang, Z., & Wu, M. (2015) · Scientific Reports · doi:10.1038/srep07949 · Cited by 165 · see citing works

Origins of mitochondria and hydrogenosomes

Andersson, S. G. E., & Kurland, C. G. (1999) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(99)00013-2 · Cited by 161 · see citing works

Symbiosis in eukaryotic evolution

López-García, P., Eme, L., & Moreira, D. (2017) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2017.02.031 · Cited by 154 · see citing works

Shaping the mitochondrial proteome

Gabaldón, T., & Huynen, M. A. (2004) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2004.07.011 · Cited by 150 · see citing works

Phylogenomic Evidence for the Presence of a Flagellum and cbb3 Oxidase in the Free-Living Mitochondrial Ancestor

Sassera, D., Lo, N. C., Epis, S., D’Auria, G., Montagna, M., Comandatore, F., Horner, D. S., Peretó, J. G., Luciano, A. M., Franciosi, F., et al. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr159 · Cited by 150 · see citing works

Organelles that illuminate the origins of Trichomonas hydrogenosomes and Giardia mitosomes

Leger, M. M., Kolísko, M., Kamikawa, R., Stairs, C. W., Kume, K., Čepička, I., Silberman, J. D., Andersson, J. O., Xu, F., Yabuki, A., et al. (2017) · Nature Ecology & Evolution · doi:10.1038/s41559-017-0092 · Cited by 147 · see citing works

Origin of mitochondria by intracellular enslavement of a photosynthetic purple bacterium

Cavalier‐Smith, T. (2006) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2006.3531 · Cited by 145 · see citing works

Genome Phylogenies Indicate a Meaningful α-Proteobacterial Phylogeny and Support a Grouping of the Mitochondria with the Rickettsiales

Fitzpatrick, D. A., Creevey, C. J., & McInerney, J. O. (2005) · Molecular Biology and Evolution · doi:10.1093/molbev/msj009 · Cited by 142 · see citing works

Open Questions on the Origin of Eukaryotes

López-García, P., & Moreira, D. (2015) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2015.09.005 · Cited by 135 · see citing works

Gene transfers from diverse bacteria compensate for reductive genome evolution in the chromatophore of Paulinella chromatophora

Nowack, E., Price, D. C., Bhattacharya, D., Singer, A., Melkonian, M., & Grossman, A. (2016) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.1608016113 · Cited by 132 · see citing works

Lokiarchaeon is hydrogen dependent

Sousa, F. L., Neukirchen, S., Allen, J. F., Lane, N. J., & Martin, W. F. (2016) · Nature Microbiology · doi:10.1038/nmicrobiol.2016.34 · Cited by 129 · see citing works

Multiple secondary origins of the anaerobic lifestyle in eukaryotes

Martin Embley, T. (2006) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2006.1844 · Cited by 124 · see citing works

From archaeon to eukaryote: the evolutionary dark ages of the eukaryotic cell

Martijn, J., & Ettema, T. J. G. (2013) · Biochemical Society Transactions · doi:10.1042/bst20120292 · Cited by 123 · see citing works

From Endosymbiont to Host-Controlled Organelle: The Hijacking of Mitochondrial Protein Synthesis and Metabolism

Gabaldón, T., & Huynen, M. A. (2007) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0030219 · Cited by 123 · see citing works

Endosymbiosis: The feeling is not mutual

Keeling, P. J., & McCutcheon, J. P. (2017) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2017.06.008 · Cited by 121 · see citing works

Ancient Homology of the Mitochondrial Contact Site and Cristae Organizing System Points to an Endosymbiotic Origin of Mitochondrial Cristae

Muñoz-Gómez, S. A., Slamovits, C. H., Dacks, J. B., Baier, K. A., Spencer, K. D., & Wideman, J. G. (2015) · Current Biology · doi:10.1016/j.cub.2015.04.006 · Cited by 120 · see citing works

An Intestinal Parasitic Protist, Entamoeba histolytica, Possesses a Non-redundant Nitrogen Fixation-like System for Iron-Sulfur Cluster Assembly under Anaerobic Conditions

Ali, V., Shigeta, Y., Tokumoto, U., Takahashi, Y., & Nozaki, T. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313314200 · Cited by 117 · see citing works

Origin and evolution of metabolic sub-cellular compartmentalization in eukaryotes

Gabaldón, T., & Pittis, A. A. (2015) · Biochimie · doi:10.1016/j.biochi.2015.03.021 · Cited by 117 · see citing works

The changing view of eukaryogenesis – fossils, cells, lineages and how they all come together

Dacks, J., Field, M. C., Buick, R., Eme, L., Gribaldo, S., Roger, A., Brochier-Armanet, C., & Devos, D. P. (2016) · Journal of Cell Science · doi:10.1242/jcs.178566 · Cited by 115 · see citing works

The chaperone connection to the origins of the eukaryotic organelles

Viale, A. M., & Arakaki, A. K. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)80446-x · Cited by 112 · see citing works

A SUF Fe-S Cluster Biogenesis System in the Mitochondrion-Related Organelles of the Anaerobic Protist Pygsuia

Stairs, C. W., Eme, L., Brown, M. W., Mutsaers, C., Susko, E., Dellaire, G., Soanes, D. M., van der Giezen, M., & Roger, A. J. (2014) · Current Biology · doi:10.1016/j.cub.2014.04.033 · Cited by 110 · see citing works

The origin of mitochondrial cristae from alphaproteobacteria

Muñoz-Gómez, S. A., Wideman, J. G., Roger, A. J., & Slamovits, C. H. (2016) · Molecular Biology and Evolution · doi:10.1093/molbev/msw298 · Cited by 106 · see citing works

The Ancient and Widespread Nature of the ER–Mitochondria Encounter Structure

Wideman, J. G., Gawryluk, R. M. R., Gray, M. W., & Dacks, J. B. (2013) · Molecular Biology and Evolution · doi:10.1093/molbev/mst120 · Cited by 102 · see citing works

Massively Convergent Evolution for Ribosomal Protein Gene Content in Plastid and Mitochondrial Genomes

Maier, U., Zauner, S., Woehle, C., Bolte, K., Hempel, F., Allen, J. F., & Martin, W. F. (2013) · Genome Biology and Evolution · doi:10.1093/gbe/evt181 · Cited by 102 · see citing works

The Origin and Evolution of The Cell

(1993) · doi:10.1142/1909 · Cited by 101 · see citing works

A new α‐proteobacterial clade of Bdellovibrio ‐like predators: implications for the mitochondrial endosymbiotic theory

Davidov, Y., Huchon, D., Koval, S. F., & Jurkevitch, É. (2006) · Environmental Microbiology · doi:10.1111/j.1462-2920.2006.01101.x · Cited by 101 · see citing works

Predation between prokaryotes and the origin of eukaryotes

Davidov, Y., & Jurkevitch, É. (2009) · BioEssays · doi:10.1002/bies.200900018 · Cited by 99 · see citing works

Phylogenetic Distributions and Histories of Proteins Involved in Anaerobic Pyruvate Metabolism in Eukaryotes

Hug, L. A., Stechmann, A., & Roger, A. J. (2009) · Molecular Biology and Evolution · doi:10.1093/molbev/msp237 · Cited by 98 · see citing works

Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis

Freibert, S., Goldberg, A. V., Hacker, C., Molik, S., Dean, P., Williams, T. A., Nakjang, S., Long, S., Sendra, K. M., Bill, E., et al. (2017) · Nature Communications · doi:10.1038/ncomms13932 · Cited by 98 · see citing works

Horizontal gene transfer in osmotrophs: playing with public goods

Richards, T. A., & Talbot, N. J. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3108 · Cited by 97 · see citing works

Mosaic origin of the mitochondrial proteome

Szklarczyk, R., & Huynen, M. A. (2010) · PROTEOMICS · doi:10.1002/pmic.201000329 · Cited by 89 · see citing works

Eukaryotic Pyruvate Formate Lyase and Its Activating Enzyme Were Acquired Laterally from a Firmicute

Stairs, C. W., Roger, A. J., & Hampl, V. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr032 · Cited by 85 · see citing works

Divergent Mitochondrial Respiratory Chains in Phototrophic Relatives of Apicomplexan Parasites

Flegontov, P., Michálek, J., Janouškovec, J., Lai, D., Jirků, M., Hajdušková, E., Tomčala, A., Otto, T. D., Keeling, P. J., Pain, A., et al. (2015) · Molecular Biology and Evolution · doi:10.1093/molbev/msv021 · Cited by 85 · see citing works

The Organellar Genome and Metabolic Potential of the Hydrogen-Producing Mitochondrion of Nyctotherus ovalis

de Graaf, R. M., Ricard, G., van Alen, T. A., Duarte, I., Dutilh, B. E., Burgtorf, C., Kuiper, J. W., van der Staay, G. W. M., Tielens, A. G. M., Huynen, M. A., et al. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr059 · Cited by 81 · see citing works

Wheat embryo mitochondrial 18S ribosomal RNA: evidence for its prokaryotic nature

Bonen, L., Cunningham, R. S., Gray, M. W., & Doolittle, W. F. (1977) · Nucleic Acids Research · doi:10.1093/nar/4.3.663 · Cited by 80 · see citing works

The SAR11 Group of Alpha-Proteobacteria Is Not Related to the Origin of Mitochondria

Rodríguez‐Ezpeleta, N., & Embley, T. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030520 · Cited by 78 · see citing works

A Complex Endomembrane System in the Archaeon Ignicoccus hospitalis Tapped by Nanoarchaeum equitans

Heimerl, T., Flechsler, J., Pickl, C., Heinz, V., Salecker, B., Zweck, J., Wanner, G., Geimer, S., Samson, R. Y., Bell, S. D., et al. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01072 · Cited by 78 · see citing works

NIF-type iron-sulfur cluster assembly system is duplicated and distributed in the mitochondria and cytosol of Mastigamoeba balamuthi

Nývltová, E., Šuťák, R., Harant, K., Šedinová, M., Hrdý, I., Pačes, J., Vlček, Č., & Tachezy, J. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219590110 · Cited by 77 · see citing works

Recent Advances in the Composition and Heterogeneity of the Arabidopsis Mitochondrial Proteome

Lee, C. P., Taylor, N. L., & Millar, A. H. (2013) · Frontiers in Plant Science · doi:10.3389/fpls.2013.00004 · Cited by 76 · see citing works

An ancestral bacterial division system is widespread in eukaryotic mitochondria

Leger, M. M., Petrů, M., Žárský, V., Eme, L., Vlček, Č., Harding, T., Lang, B. F., Eliáš, M., Doležal, P., & Roger, A. J. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1421392112 · Cited by 76 · see citing works

Phylogenomic Reconstruction Indicates Mitochondrial Ancestor Was an Energy Parasite

Wang, Z., & Wu, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0110685 · Cited by 75 · see citing works

Lateral Gene Transfer and Gene Duplication Played a Key Role in the Evolution of Mastigamoeba balamuthi Hydrogenosomes

Nývltová, E., Stairs, C. W., Hrdý, I., Rídl, J., Mach, J., Pačes, J., Roger, A. J., & Tachezy, J. (2015) · Molecular Biology and Evolution · doi:10.1093/molbev/msu408 · Cited by 70 · see citing works

A Phylometagenomic Exploration of Oceanic Alphaproteobacteria Reveals Mitochondrial Relatives Unrelated to the SAR11 Clade

Brindefalk, B., Ettema, T. J. G., Viklund, J., Thollesson, M., & Andersson, S. G. E. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024457 · Cited by 67 · see citing works

Why genes persist in organelle genomes.

Daley, D. O., & Whelan, J. (2005) · Genome biology · doi:10.1186/gb-2005-6-5-110 · Cited by 67 · see citing works

Minor modifications and major adaptations: The evolution of molecular machines driving mitochondrial protein import

Hewitt, V. L., Alcock, F., & Lithgow, T. J. (2010) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2010.07.019 · Cited by 66 · see citing works

The Earliest Stages of Mitochondrial Adaptation to Low Oxygen Revealed in a Novel Rhizarian

Gawryluk, R. M. R., Kamikawa, R., Stairs, C. W., Silberman, J. D., Brown, M. W., & Roger, A. J. (2016) · Current Biology · doi:10.1016/j.cub.2016.08.025 · Cited by 66 · see citing works

Deep Origin of Plastid/Parasite ATP/ADP Translocases

Amiri, H., Karlberg, O., & Andersson, S. G. E. (2003) · Journal of Molecular Evolution · doi:10.1007/s00239-002-2387-0 · Cited by 63 · see citing works

Compositional complexity of the mitochondrial proteome of a unicellular eukaryote (Acanthamoeba castellanii, supergroup Amoebozoa) rivals that of animals, fungi, and plants

Gawryluk, R. M. R., Chisholm, K. A., Pinto, D. M., & Gray, M. W. (2014) · Journal of Proteomics · doi:10.1016/j.jprot.2014.07.005 · Cited by 58 · see citing works

Phylogenomic Analysis of Odyssella thessalonicensis Fortifies the Common Origin of Rickettsiales, Pelagibacter ubique and Reclimonas americana Mitochondrion

Georgiades, K., Madoui, M., Le, P. T., Robert, C., & Raoult, D. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024857 · Cited by 57 · see citing works

Novel Hydrogenosomes in the Microaerophilic Jakobid Stygiella incarcerata

Leger, M. M., Eme, L., Hug, L. A., & Roger, A. J. (2016) · Molecular Biology and Evolution · doi:10.1093/molbev/msw103 · Cited by 56 · see citing works

Mitochondrial contact sites as platforms for phospholipid exchange

Dimmer, K. S., & Rapaport, D. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2016.07.010 · Cited by 56 · see citing works

Endosymbionts and mitochondrial origins

Woese, C. R. (1977) · Journal of Molecular Evolution · doi:10.1007/bf01751802 · Cited by 55 · see citing works

Ancient dynamin segments capture early stages of host–mitochondrial integration

Purkanti, R., & Thattai, M. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1407163112 · Cited by 51 · see citing works

The Dual Origin of the Yeast Mitochondrial Proteome

Karlberg, O., Canbäck, B., Kurland, C. G., et al. (2000) · Yeast · doi:10.1155/2000/597406 · Cited by 50 · see citing works

Lateral gene transfers and the origins of the eukaryote proteome: a view from microbial parasites

Hirt, R. P., Alsmark, C. M., & Embley, T. M. (2014) · Current Opinion in Microbiology · doi:10.1016/j.mib.2014.11.018 · Cited by 47 · see citing works

The evolution of ERMIONE in mitochondrial biogenesis and lipid homeostasis: An evolutionary view from comparative cell biology

Wideman, J. G., & Muñoz-Gómez, S. A. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2016.01.015 · Cited by 47 · see citing works

Comparative and Phylogenomic Evidence That the Alphaproteobacterium HIMB59 Is Not a Member of the Oceanic SAR11 Clade

Viklund, J., Martijn, J., Ettema, T. J. G., & Andersson, S. G. E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078858 · Cited by 43 · see citing works

Endosymbiotic purple non-sulphur bacteria in an anaerobic ciliated protozoon

Fenchel, T., & Bernard, C. (1993) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1993.tb06289.x · Cited by 43 · see citing works

From microbiology to cell biology: when an intracellular bacterium becomes part of its host cell

McCutcheon, J. P. (2016) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2016.05.008 · Cited by 43 · see citing works

Late Mitochondrial Origin Is an Artifact

Martin, W. F., Roettger, M., Ku, C., Garg, S. G., Nelson-Sathi, S., & Landan, G. (2017) · Genome Biology and Evolution · doi:10.1093/gbe/evx027 · Cited by 42 · see citing works

Evidence for a Hydrogenosomal-Type Anaerobic ATP Generation Pathway in Acanthamoeba castellanii

Leger, M. M., Gawryluk, R. M. R., Gray, M. W., & Roger, A. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069532 · Cited by 42 · see citing works

Alternating terminal electron‐acceptors at the basis of symbiogenesis: How oxygen ignited eukaryotic evolution

Speijer, D. (2017) · BioEssays · doi:10.1002/bies.201600174 · Cited by 40 · see citing works

Bacterial genome chimaerism and the origin of mitochondria

Abhishek, A., Bavishi, A., Bavishi, A., & Choudhary, M. (2011) · Canadian Journal of Microbiology · doi:10.1139/w10-099 · Cited by 36 · see citing works

The rhizome of Reclinomonas americana, Homo sapiens, Pediculus humanus and Saccharomyces cerevisiae mitochondria

Georgiades, K., & Raoult, D. (2011) · Biology Direct · doi:10.1186/1745-6150-6-55 · Cited by 36 · see citing works

Alpha proteobacterial ancestry of the [Fe-Fe]-hydrogenases in anaerobic eukaryotes

Esposti, M. D., Cortez, D., Lozano, L., Rasmussen, S., Nielsen, H. B., & Martínez‐Romero, E. (2016) · Biology Direct · doi:10.1186/s13062-016-0136-3 · Cited by 36 · see citing works

Why mitochondria need a genome revisited

Björkholm, P., Ernst, A. M., Hagström, E., & Andersson, S. G. E. (2016) · FEBS Letters · doi:10.1002/1873-3468.12510 · Cited by 34 · see citing works

OsmC and incomplete glycine decarboxylase complex mediate reductive detoxification of peroxides in hydrogenosomes of Trichomonas vaginalis

Nývltová, E., Smutná, T., Tachezy, J., & Hrdý, I. (2016) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2016.01.006 · Cited by 33 · see citing works

Connection of Protein Transport and Organelle Contact Sites in Mitochondria

Ellenrieder, L., Rampelt, H., & Becker, T. (2017) · Journal of Molecular Biology · doi:10.1016/j.jmb.2017.05.023 · Cited by 33 · see citing works

Aerobic mitochondria of parasitic protists: Diverse genomes and complex functions

Zı́ková, A., Hampl, V., Paris, Z., Týč, J., & Lukeš, J. (2016) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2016.02.007 · Cited by 25 · see citing works

Endosymbiont or host: who drove mitochondrial and plastid evolution?

Gross, J., & Bhattacharya, D. (2011) · Biology Direct · doi:10.1186/1745-6150-6-12 · Cited by 20 · see citing works

Protists and the Wild, Wild West of Gene Expression: New Frontiers, Lawlessness, and Misfits.

Smith, D., & Keeling, P. (2016) · Annual Review of Microbiology · doi:10.1146/annurev-micro-102215-095448 · Cited by 17 · see citing works

On phylogenetic branch lengths distribution and the late acquistion of mitochondriaPreprint

Pittis, A. A., & Gabaldón, T. (2016) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/064873 · Cited by 11 · see citing works

Modifications and Innovations in the Evolution of Mitochondrial Protein Import Pathways

Hewitt, V. L., Lithgow, T. J., & Waller, R. F. (2013) · Springer eBooks · doi:10.1007/978-3-7091-1303-5_2 · Cited by 9 · see citing works

One plus One equals One

Richardson, D. H. S. (2018) · Proceedings of the Nova Scotian Institute of Science · doi:10.15273/pnsis.v49i2.8166 · Cited by 2 · see citing works

Mitochondrial control of inflammation

Marchi, S., Guilbaud, E., Tait, S. W. G., Yamazaki, T., & Galluzzi, L. (2023) · Nature Reviews Immunology · doi:10.1038/s41577-022-00760-x · Cited by 1,027 · see citing works

Mitochondrial and metabolic dysfunction in ageing and age-related diseases

Amorim, J. A., Coppotelli, G., Rolo, A. P., Palmeira, C. M., Ross, J. M., & Sinclair, D. A. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-021-00626-7 · Cited by 990 · see citing works

Mitochondrial DNA in inflammation and immunity

Riley, J. S., & Tait, S. W. G. (2020) · EMBO Reports · doi:10.15252/embr.201949799 · Cited by 876 · see citing works

Mitochondrial Dysfunction and Oxidative Stress in Alzheimer’s Disease

Misrani, A., Tabassum, S., & Yang, L. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.617588 · Cited by 654 · see citing works

Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction

Monzel, A. S., Enrı́quez, J. A., & Picard, M. A. (2023) · Nature Metabolism · doi:10.1038/s42255-023-00783-1 · Cited by 618 · see citing works

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

Cirino, G., Szabó, C., & Papapetropoulos, A. (2022) · Physiological Reviews · doi:10.1152/physrev.00028.2021 · Cited by 568 · see citing works

The power and potential of mitochondria transfer

Borcherding, N. C., & Brestoff, J. R. (2023) · Nature · doi:10.1038/s41586-023-06537-z · Cited by 525 · see citing works

Quality control of the mitochondrial proteome

Song, J., Herrmann, J. M., & Becker, T. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00300-2 · Cited by 492 · see citing works

Integrated genomic and fossil evidence illuminates life’s early evolution and eukaryote origin

Betts, H. C., Puttick, M. N., Clark, J. W., Williams, T. A., Donoghue, P. C. J., & Pisani, D. (2018) · Nature Ecology & Evolution · doi:10.1038/s41559-018-0644-x · Cited by 437 · see citing works

The emerging mechanisms and functions of microautophagy

Wang, L., Klionsky, D. J., & Shen, H. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00529-z · Cited by 473 · see citing works

Mitochondria and cell death-associated inflammation

Vringer, E., & Tait, S. W. G. (2022) · Cell Death and Differentiation · doi:10.1038/s41418-022-01094-w · Cited by 441 · see citing works

Mitochondrial iron–sulfur clusters: Structure, function, and an emerging role in vascular biology

Read, A. D., Bentley, R. E. T., Archer, S. L., & Dunham‐Snary, K. J. (2021) · Redox Biology · doi:10.1016/j.redox.2021.102164 · Cited by 418 · see citing works

Aggregation-Induced Emission (AIE), Life and Health

Wang, H., Li, Q., Alam, P., Bai, H., Bhalla, V., Bryce, M. R., Cao, M., Chen, C., Chen, S., Chen, X., et al. (2023) · ACS Nano · doi:10.1021/acsnano.3c03925 · Cited by 396 · see citing works

Metabolism

Judge, A., & Dodd, M. S. (2020) · Essays in Biochemistry · doi:10.1042/ebc20190041 · Cited by 373 · see citing works

Mitochondrial Functions in Infection and Immunity

Tiku, V., Tan, M., & Đikić, I. (2020) · Trends in Cell Biology · doi:10.1016/j.tcb.2020.01.006 · Cited by 358 · see citing works

Probiotics and the microbiota-gut-brain axis: Focus on psychiatry

Mörkl, S., Butler, M. I., Holl, A., Cryan, J. F., & Dinan, T. G. (2020) · Current Nutrition Reports · doi:10.1007/s13668-020-00313-5 · Cited by 337 · see citing works

Cytoplasmic DNA: sources, sensing, and role in aging and disease

Miller, K. N., Victorelli, S. G., Salmonowicz, H., Dasgupta, N., Liu, T., Passos, J. F., & Adams, P. D. (2021) · Cell · doi:10.1016/j.cell.2021.09.034 · Cited by 288 · see citing works

Plant organellar genomes: much done, much more to do

Wang, J., Kan, S., Liao, X., Zhou, J., Tembrock, L. R., Daniell, H., Jin, S., & Wu, Z. (2024) · Trends in Plant Science · doi:10.1016/j.tplants.2023.12.014 · Cited by 288 · see citing works

Hydrogen sulfide signaling in mitochondria and disease

Murphy, B., Bhattacharya, R., & Mukherjee, P. (2019) · The FASEB Journal · doi:10.1096/fj.201901304r · Cited by 279 · see citing works

Phylogenomics provides robust support for a two-domains tree of life

Williams, T. A., Cox, C. J., Foster, P. G., Szöllősi, G. J., & Embley, T. M. (2019) · Nature Ecology & Evolution · doi:10.1038/s41559-019-1040-x · Cited by 274 · see citing works

Mitochondrial quality control in health and in Parkinson’s disease

Eldeeb, M. A., Thomas, R. A., Ragheb, M. A., Fallahi, A., & Fon, E. A. (2022) · Physiological Reviews · doi:10.1152/physrev.00041.2021 · Cited by 276 · see citing works

Shaping Neuronal Fate: Functional Heterogeneity of Direct Microglia-Neuron Interactions

Cserép, C., Pósfai, B., & Dénes, Á. (2021) · Neuron · doi:10.1016/j.neuron.2020.11.007 · Cited by 256 · see citing works

Mitophagy in Cancer: A Tale of Adaptation

Vara‐Pérez, M., Felipe‐Abrio, B., & Agostinis, P. (2019) · Cells · doi:10.3390/cells8050493 · Cited by 256 · see citing works

Getting out what you put in: Copper in mitochondria and its impacts on human disease

Cobine, P. A., Moore, S. A., & Leary, S. C. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2020.118867 · Cited by 253 · see citing works

Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes

Wei, W., Schon, K. R., Elgar, G. S., Orioli, A., Tanguy, M., Giess, A. P., Tischkowitz, M. D., Caulfield, M. J., & Chinnery, P. F. (2022) · Nature · doi:10.1038/s41586-022-05288-7 · Cited by 250 · see citing works

Cytonuclear integration and coevolution

Sloan, D. B., Warren, J., Williams, A. M., Wu, Z.-Q., Abdel-Ghany, S., Chicco, A., & Havird, J. C. (2018) · Nature reviews genetics · doi:10.1038/s41576-018-0035-9 · Cited by 205 · see citing works

The Life of an Insect Endosymbiont from the Cradle to the Grave

McCutcheon, J. P., Boyd, B. M., & Dale, C. (2019) · Current Biology · doi:10.1016/j.cub.2019.03.032 · Cited by 244 · see citing works

Cyanobacteria evolution: Insight from the fossil record

Demoulin, C., Lara, Y. J., Cornet, L., François, C., Baurain, D., Wilmotte, A., & Javaux, E. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.05.007 · Cited by 239 · see citing works

PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders

Jamwal, S., Blackburn, J. K., & Elsworth, J. D. (2021) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107705 · Cited by 236 · see citing works

Mechanistic concepts of iron-sulfur protein biogenesis in Biology

Braymer, J. J., Freibert, S., Rakwalska‐Bange, M., & Lill, R. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2020.118863 · Cited by 235 · see citing works

Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases

Liu, Z., Sun, Y., Qi, Z., Cao, L., & Ding, S. (2022) · Cell & Bioscience · doi:10.1186/s13578-022-00805-7 · Cited by 235 · see citing works

Molecular Mechanisms of mtDNA-Mediated Inflammation

Gaetano, A. D., Solodka, K., Zanini, G., Selleri, V., Mattioli, A. V., Nasi, M., & Pinti, M. (2021) · Cells · doi:10.3390/cells10112898 · Cited by 235 · see citing works

Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance

Burns, J. S., & Manda, G. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18122755 · Cited by 220 · see citing works

Proposal of the reverse flow model for the origin of the eukaryotic cell based on comparative analyses of Asgard archaeal metabolism

Spang, A., Stairs, C. W., Dombrowski, N., Eme, L., Lombard, J., Caceres, E. F., Greening, C., Baker, B. J., & Ettema, T. J. G. (2019) · Nature Microbiology · doi:10.1038/s41564-019-0406-9 · Cited by 200 · see citing works

Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy

Wang, S., Gai, L., Chen, Y., Ji, X., Lü, H., & Guo, Z. (2024) · Chemical Society Reviews · doi:10.1039/d3cs00456b · Cited by 214 · see citing works

The Syntrophy hypothesis for the origin of eukaryotes revisited

López-García, P., & Moreira, D. (2020) · Nature Microbiology · doi:10.1038/s41564-020-0710-4 · Cited by 201 · see citing works

DNA Repair and the Stability of the Plant Mitochondrial Genome

Chevigny, N., Schatz-Daas, D., Weber‐Lotfi, F., & Gualberto, J. M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21010328 · Cited by 207 · see citing works

Mitochondrial quality control in pulmonary fibrosis

Larson‐Casey, J. L., He, C., & Carter, A. B. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101426 · Cited by 190 · see citing works

Mitochondrial function in development and disease

Rossmann, M. P., Dubois, S. M., Agarwal, S., & Zon, L. I. (2021) · Disease Models & Mechanisms · doi:10.1242/dmm.048912 · Cited by 191 · see citing works

Mitochondria transfer enhances proliferation, migration, and osteogenic differentiation of bone marrow mesenchymal stem cell and promotes bone defect healing

Guo, Y., Chi, X., Wang, Y., Heng, B. C., Wei, Y. Q., Zhang, X., Zhao, H., Yin, Y., & Deng, X. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-01704-9 · Cited by 183 · see citing works

Magnesium Is a Key Player in Neuronal Maturation and Neuropathology

Yamanaka, R., Shindo, Y., & Oka, K. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20143439 · Cited by 179 · see citing works

Recommendations for mitochondria transfer and transplantation nomenclature and characterization

Brestoff, J. R., Singh, K. K., Aquilano, K., Becker, L. B., Berridge, M. V., Boilard, É., Caicedo, A., Crewe, C., Enrı́quez, J. A., Gao, J., et al. (2025) · Nature Metabolism · doi:10.1038/s42255-024-01200-x · Cited by 180 · see citing works

Mitochondria in Neuroprotection by Phytochemicals: Bioactive Polyphenols Modulate Mitochondrial Apoptosis System, Function and Structure

Naoi, M., Wu, Y., Shamoto‐Nagai, M., & Maruyama, W. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20102451 · Cited by 170 · see citing works

Deregulated mitochondrial microRNAs in Alzheimer's disease: Focus on synapse and mitochondria

Gowda, P., Reddy, P. H., & Kumar, S. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101529 · Cited by 166 · see citing works

Recent advances in understanding mitochondrial genome diversity

Zardoya, R. (2020) · F1000Research · doi:10.12688/f1000research.21490.1 · Cited by 159 · see citing works

Eukaryogenesis and oxygen in Earth history

Mills, D. B., Boyle, R. A., Daines, S. J., Sperling, E. A., Pisani, D., Donoghue, P. C. J., & Lenton, T. M. (2022) · Nature Ecology & Evolution · doi:10.1038/s41559-022-01733-y · Cited by 153 · see citing works

Mitochondrial DNA drives noncanonical inflammation activation via cGAS–STING signaling pathway in retinal microvascular endothelial cells

Guo, Y., Gu, R., Gan, D., Hu, F., Li, G., & Xu, G. (2020) · Cell Communication and Signaling · doi:10.1186/s12964-020-00637-3 · Cited by 151 · see citing works

A break in mitochondrial endosymbiosis as a basis for inflammatory diseases

Murphy, M. P., & O’Neill, L. A. J. (2024) · Nature · doi:10.1038/s41586-023-06866-z · Cited by 138 · see citing works

An updated phylogeny of the Alphaproteobacteria reveals that the parasitic Rickettsiales and Holosporales have independent origins

(2019) · doi:10.7554/elife.42535 · Cited by 130 · see citing works

Cytosolic Events in the Biogenesis of Mitochondrial Proteins.

Bykov, Y., Rapaport, D., Herrmann, J. M., & Schuldiner, M. (2020) · TIBS -Trends in Biochemical Sciences. Regular ed · doi:10.1016/j.tibs.2020.04.001 · Cited by 113 · see citing works

Mitochondria‐targeted nanoparticles in treatment of neurodegenerative diseases

Zhang, Y., Yang, H. N., Wei, D., Zhang, X., Wang, J., Wu, X., & Chang, J. K. (2021) · Exploration · doi:10.1002/exp.20210115 · Cited by 133 · see citing works

The Similarities between Human Mitochondria and Bacteria in the Context of Structure, Genome, and Base Excision Repair System

Boguszewska, K., Szewczuk, M., Kaźmierczak-Barańska, J., & Karwowski, B. T. (2020) · Molecules · doi:10.3390/molecules25122857 · Cited by 144 · see citing works

Site-and-branch-heterogeneous analyses of an expanded dataset favour mitochondria as sister to known Alphaproteobacteria

Muñoz-Gómez, S. A., Susko, E., Williamson, K., Eme, L., Slamovits, C. H., Moreira, D., López-García, P., & Roger, A. J. (2022) · Nature Ecology & Evolution · doi:10.1038/s41559-021-01638-2 · Cited by 111 · see citing works

Determinants, maintenance, and function of organellar pH

Freeman, S. A., Grinstein, S., & Orlowski, J. (2022) · Physiological Reviews · doi:10.1152/physrev.00009.2022 · Cited by 127 · see citing works

Phylogenetic analyses with systematic taxon sampling show that mitochondria branch within Alphaproteobacteria

Fan, L., Wu, D., Goremykin, V. V., Xiao, J., Xu, Y., Garg, S. G., Zhang, C., Martin, W. F., & Zhu, R. (2020) · Nature Ecology & Evolution · doi:10.1038/s41559-020-1239-x · Cited by 123 · see citing works

Small is big in Arabidopsis mitochondrial ribosome

Waltz, F., Nguyen, T.-T., Arrivé, M., Bochler, A., Chicher, J., Hammann, P., Kühn, L., Quadrado, M., Mireau, H., Hashem, Y., et al. (2019) · Nature Plants · doi:10.1038/s41477-018-0339-y · Cited by 112 · see citing works

Assembly of the complete mitochondrial genome of an endemic plant, Scutellaria tsinyunensis, revealed the existence of two conformations generated by a repeat-mediated recombination

Li, J., Xu, Y., Shan, Y., Pei, X., Yong, S., Liu, C., & Yu, J. (2021) · Planta · doi:10.1007/s00425-021-03684-3 · Cited by 121 · see citing works

Improving metabarcoding taxonomic assignment: A case study of fishes in a large marine ecosystem

Gold, Z. J., Curd, E., Goodwin, K. D., Choi, E. S., Frable, B. W., Thompson, A., Walker, H. J., Burton, R. S., Kacev, D., Martz, L. D., et al. (2021) · Molecular Ecology Resources · doi:10.1111/1755-0998.13450 · Cited by 121 · see citing works

The emerging view on the origin and early evolution of eukaryotic cells

Vosseberg, J., van Hooff, J. J. E., Köstlbacher, S., Panagiotou, K., Tamarit, D., & Ettema, T. J. G. (2024) · Nature · doi:10.1038/s41586-024-07677-6 · Cited by 122 · see citing works

Roles of mitochondria in neuronal development

Son, G., & Han, J. (2018) · BMB Reports · doi:10.5483/bmbrep.2018.51.11.226 · Cited by 117 · see citing works

Assembly of the Complexes of the Oxidative Phosphorylation System in Land Plant Mitochondria

Meyer, E. H., Welchen, E., & Carrie, C. (2019) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-050718-100412 · Cited by 115 · see citing works

A cnidarian parasite of salmon (Myxozoa: Henneguya ) lacks a mitochondrial genome

Yahalomi, D., Atkinson, S. D., Neuhof, M., Chang, E. S., Philippe, H., Cartwright, P., Bartholomew, J. L., & Huchon, D. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1909907117 · Cited by 114 · see citing works

Mitochondrial Glucocorticoid Receptors and Their Actions

Kokkinopoulou, I., & Moutsatsou, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22116054 · Cited by 120 · see citing works

MicroRNAs: pioneering regulators in Alzheimer’s disease pathogenesis, diagnosis, and therapy

Li, Y.-B., Fu, Q., Guo, M., Du, Y., Chen, Y., & Cheng, Y. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03075-8 · Cited by 123 · see citing works

Mitochondrial redox systems as central hubs in plant metabolism and signaling

Aken, O. V. (2021) · PLANT PHYSIOLOGY · doi:10.1093/plphys/kiab101 · Cited by 113 · see citing works

Anaerobic endosymbiont generates energy for ciliate host by denitrification

Graf, J. S., Schorn, S., Kitzinger, K., Ahmerkamp, S., Woehle, C., Hüettel, B., Schubert, C. J., Kuypers, M. M. M., & Milucka, J. (2021) · Nature · doi:10.1038/s41586-021-03297-6 · Cited by 113 · see citing works

Timing the origin of eukaryotic cellular complexity with ancient duplications

Vosseberg, J., van Hooff, J. J. E., Marcet-Houben, M., van Vlimmeren, A., van Wijk, L. M., Gabaldón, T., & Snel, B. (2020) · Nature Ecology & Evolution · doi:10.1038/s41559-020-01320-z · Cited by 110 · see citing works

Selfish Mitonuclear Conflict

Havird, J. C., Forsythe, E. S., Williams, A. M., Werren, J. H., Dowling, D. K., & Sloan, D. B. (2019) · Current Biology · doi:10.1016/j.cub.2019.03.020 · Cited by 109 · see citing works

Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune‐related Pathways in Mammalian Cells

Bryant, J. D., Lei, Y., VanPortfliet, J. J., Winters, A. D., & West, A. P. (2022) · Current Protocols · doi:10.1002/cpz1.372 · Cited by 109 · see citing works

Interaction between Intracellular Bacterial Pathogens and Host Cell Mitochondria

Spier, A., Stavru, F., & Cossart, P. (2019) · Microbiology Spectrum · doi:10.1128/microbiolspec.bai-0016-2019 · Cited by 108 · see citing works

Challenges Facing CRISPR/Cas9-Based Genome Editing in Plants

Son, S., & Park, S. R. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.902413 · Cited by 111 · see citing works

Ca2+ handling at the mitochondria-ER contact sites in neurodegeneration

Lim, D., Dematteis, G., Tapella, L., Genazzani, A. A., Calí, T., Brini, M., & Verkhratsky, A. (2021) · Cell Calcium · doi:10.1016/j.ceca.2021.102453 · Cited by 105 · see citing works

High-Performance Near-Infrared Aggregation-Induced Emission Luminogen with Mitophagy Regulating Capability for Multimodal Cancer Theranostics

Li, Y., Zhuang, J., Lü, Y., Li, N., Gu, M., Xia, J., Zhao, N., & Tang, B. Z. (2021) · ACS Nano · doi:10.1021/acsnano.1c08928 · Cited by 99 · see citing works

Mesenchymal stem cell-mediated transfer of mitochondria: mechanisms and functional impact

Velarde, F., Ezquerra, S., Delbruyere, X., Caicedo, A., Hidalgo, Y., & Khoury, M. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04207-3 · Cited by 99 · see citing works

Mitochondrial Dynamics and Mitophagy in Cardiometabolic Disease

Lin, J., Duan, J., Wang, Q., Xu, S., Zhou, S., & Yao, K. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.917135 · Cited by 101 · see citing works

Mitochondrial Cristae Architecture and Functions: Lessons from Minimal Model Systems

Joubert, F., & Puff, N. (2021) · Membranes · doi:10.3390/membranes11070465 · Cited by 97 · see citing works

Wasteful, essential, evolutionary stepping stone? The multiple personalities of the photorespiratory pathway

Fernie, A. R., & Bauwe, H. (2020) · The Plant Journal · doi:10.1111/tpj.14669 · Cited by 94 · see citing works

Concepts of the last eukaryotic common ancestor

O’Malley, M. A., Leger, M. M., Wideman, J. G., & Ruiz‐Trillo, I. (2019) · Nature Ecology & Evolution · doi:10.1038/s41559-019-0796-3 · Cited by 93 · see citing works

Origins of eukaryotic excitability

Wan, K. Y., & Jékely, G. (2021) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2019.0758 · Cited by 97 · see citing works

Constructive Neutral Evolution 20 Years Later

Muñoz-Gómez, S. A., Bilolikar, G., Wideman, J. G., & Geiler‐Samerotte, K. (2021) · Journal of Molecular Evolution · doi:10.1007/s00239-021-09996-y · Cited by 94 · see citing works

Mitochondrial functions in plant immunity

Wang, J., Xu, G., Ning, Y., Wang, X., & Wang, G. (2022) · Trends in Plant Science · doi:10.1016/j.tplants.2022.04.007 · Cited by 93 · see citing works

Oxidized mitochondrial DNA: a protective signal gone awry

Xian, H., & Karin, M. (2023) · Trends in Immunology · doi:10.1016/j.it.2023.01.006 · Cited by 94 · see citing works

When cell death goes wrong: inflammatory outcomes of failed apoptosis and mitotic cell death

Bock, F. J., & Riley, J. S. (2022) · Cell Death and Differentiation · doi:10.1038/s41418-022-01082-0 · Cited by 89 · see citing works

The assembly pathway of complex I in Arabidopsis thaliana

Ligas, J., Pineau, E., Bock, R., Huynen, M. A., & Meyer, E. H. (2018) · The Plant Journal · doi:10.1111/tpj.14133 · Cited by 90 · see citing works

Mitochondrial Dysfunction at the Center of Cancer Therapy

Chiu, H. Y., Tay, E. X. Y., Ong, D. S. T., & Taneja, R. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2019.7898 · Cited by 89 · see citing works

A robustly rooted tree of eukaryotes reveals their excavate ancestry

Williamson, K., Eme, L., Baños, H., McCarthy, C. G. P., Susko, E., Kamikawa, R., Orr, R. J. S., Muñoz-Gómez, S. A., Minh, B. Q., Simpson, A. G. B., et al. (2025) · Nature · doi:10.1038/s41586-025-08709-5 · Cited by 90 · see citing works

Evolution of bacterial steroid biosynthesis and its impact on eukaryogenesis

Hoshino, Y., & Gaucher, E. A. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2101276118 · Cited by 83 · see citing works

Origin and Early Evolution of the Eukaryotic Cell

Gabaldón, T. (2021) · Annual Review of Microbiology · doi:10.1146/annurev-micro-090817-062213 · Cited by 121 · see citing works

Advances in bacterial pathways for the biosynthesis of ubiquinone

Abby, S. S., Kazemzadeh, K., Vragniau, C., Pélosi, L., & Pierrel, F. (2020) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2020.148259 · Cited by 83 · see citing works

The Genomics and Cell Biology of Host-Beneficial Intracellular Infections

McCutcheon, J. P. (2021) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-120219-024122 · Cited by 82 · see citing works

Mitochondrial Dysfunction in the Pathogenesis of Preeclampsia

Hu, X., & Zhang, L. (2022) · Current Hypertension Reports · doi:10.1007/s11906-022-01184-7 · Cited by 83 · see citing works

Enantioselective effects of cyflumetofen on microbial community and related nitrogen cycle gene function in acid-soil

Shi, L., Zhang, P., He, Y., Zeng, F., Xu, J., & He, L. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.144831 · Cited by 76 · see citing works

Mitochondrial Dysfunction in Diabetic Cardiomyopathy: The Possible Therapeutic Roles of Phenolic Acids

Jubaidi, F. F., Zainalabidin, S., Mariappan, V., & Budin, S. B. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176043 · Cited by 78 · see citing works

Interchangeable parts: The evolutionarily dynamic tRNA population in plant mitochondria

Warren, J. M., & Sloan, D. B. (2020) · Mitochondrion · doi:10.1016/j.mito.2020.03.007 · Cited by 77 · see citing works

Lactate Is Answerable for Brain Function and Treating Brain Diseases: Energy Substrates and Signal Molecule

Cai, M., Wang, H., Song, H., Yang, R., Wang, L., Xue, X., Sun, W., & Hu, J. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.800901 · Cited by 78 · see citing works

Mitochondrial Epigenetics: Non-Coding RNAs as a Novel Layer of Complexity

Cavalcante, G. C., Magalhães, L., Ribeiro-dos-Santos, Â., & Vidal, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21051838 · Cited by 71 · see citing works

Warning SINEs: Alu elements, evolution of the human brain, and the spectrum of neurological disease

Larsen, P. A., Hunnicutt, K. E., Larsen, R. J., Yoder, A. D., & Saunders, A. M. (2018) · Chromosome Research · doi:10.1007/s10577-018-9573-4 · Cited by 76 · see citing works

The origin of phagocytosis in Earth history

Mills, D. B. (2020) · Interface Focus · doi:10.1098/rsfs.2020.0019 · Cited by 76 · see citing works

Mitochondrial compartmentalization: emerging themes in structure and function

Iovine, J. C., Claypool, S. M., & Alder, N. N. (2021) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2021.06.003 · Cited by 74 · see citing works

Mitochondrial genomes revisited: why do different lineages retain different genes?

Butenko, A., Lukeš, J., Speijer, D., & Wideman, J. G. (2024) · BMC Biology · doi:10.1186/s12915-024-01824-1 · Cited by 77 · see citing works

ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ

Атабекова, Б. Б. (2024) · Habaršy. Pedagogika ġylymdary seriâsy · doi:10.51889/2959-5762.2023.80.4.019

Cloning and Characterization of Rat BAT3 cDNA

Ozaki, T., Hanaoka, E., Naka, M., et al. (1999) · DNA and Cell Biology · doi:10.1089/104454999315222 · Cited by 22 · see citing works

EFFECT OF THE NEMATODE PHASMARHABDITIS HERMAPHRODITA ON YOUNG STAGES OF THE PEST SLUG ARION LUSITANICUS

Grimm, B. (2002) · Journal of Molluscan Studies · doi:10.1093/mollus/68.1.25 · Cited by 41 · see citing works

HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53Preprint

Sasaki, T., Gan, E. C., Wakeham, A. C., Kornbluth, S. A., Mak, T. W., & Okada, H. (2007) · Genes & Development · doi:10.1101/gad.1534107 · Cited by 127 · see citing works

Anthoxanthum Mosaic Virus

Catherall, P. L. (1970) · Plant Pathology · doi:10.1111/j.1365-3059.1970.tb00999.x · Cited by 6 · see citing works