Diminished gray matter in the hippocampus of cannabis users: possible protective effects of cannabidiol

A fast diffeomorphic image registration algorithm

Ashburner, J. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.07.007 · Cited by 8,122 · see citing works

A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains

Good, C. D., Johnsrude, I. S., Ashburner, J., Henson, R. N. A., Friston, K. J., & Frackowiak, R. S. J. (2001) · NeuroImage · doi:10.1006/nimg.2001.0786 · Cited by 4,561 · see citing works

The diverse CB 1 and CB 2 receptor pharmacology of three plant cannabinoids: Δ 9 ‐tetrahydrocannabinol, cannabidiol and Δ 9 ‐tetrahydrocannabivarin

Pertwee, R. G. (2007) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707442 · Cited by 1,953 · see citing works

Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology

Bhattacharyya, S., Morrison, P. D., Fusar-Poli, P., Martin-Santos, R., Borgwardt, S., Winton-Brown, T., Nosarti, C., O' Carroll, C. M., Seal, M., Allen, P., et al. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.184 · Cited by 680 · see citing works

High-potency cannabis and the risk of psychosis

Di Forti, M., Morgan, C., Dazzan, P., Pariante, C., Mondelli, V., Marques, T. R., Handley, R., Luzi, S., Russo, M., Paparelli, A., et al. (2009) · British Journal of Psychiatry · doi:10.1192/bjp.bp.109.064220 · Cited by 567 · see citing works

Hardwiring the Brain: Endocannabinoids Shape Neuronal Connectivity

Berghuis, P., Rajnicek, A. M., Morozov, Y. M., Ross, R. A., Mulder, J., Urbán, G. M., Monory, K., Marsicano, G., Matteoli, M., Canty, A. J., et al. (2007) · Science · doi:10.1126/science.1137406 · Cited by 551 · see citing works

Regional Brain Abnormalities Associated With Long-term Heavy Cannabis Use

Yücel, M., Solowij, N., Respondek, C., Whittle, S., Fornito, A., Pantelis, C., & Lubman, D. I. (2008) · Archives of General Psychiatry · doi:10.1001/archpsyc.65.6.694 · Cited by 495 · see citing works

Cannabinoids Promote Oligodendrocyte Progenitor Survival: Involvement of Cannabinoid Receptors and Phosphatidylinositol-3 Kinase/Akt Signaling

Molina‐Holgado, E., Vela, J. M., Arévalo‐Martín, Á., Almazán, G., Molina‐Holgado, F., Borrell, J. I., & Guaza, C. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-22-09742.2002 · Cited by 420 · see citing works

Age and gender effects on human brain anatomy: A voxel-based morphometric study in healthy elderly

Smith, C. D., Chebrolu, H., Wekstein, D. R., Schmitt, F. A., & Markesbery, W. R. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.05.018 · Cited by 319 · see citing works

Cannabis, the mind and society: the hash realities

Murray, R. M., Morrison, P. D., Henquet, C., & Forti, M. D. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2253 · Cited by 319 · see citing works

Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis

Morgan, C. J. A., & Curran, H. V. (2008) · British Journal of Psychiatry · doi:10.1192/bjp.bp.107.046649 · Cited by 300 · see citing works

The Endocannabinoid System Promotes Astroglial Differentiation by Acting on Neural Progenitor Cells

Aguado, T., Palazuelos, J., Monory, K., Stella, N., Cravatt, B. F., Lutz, B., Marsicano, G., Kokaia, Z., Guzmán, M., & Galve‐Roperh, I. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3101-05.2006 · Cited by 269 · see citing works

Altered brain tissue composition in heavy marijuana users

Matochik, J. A., Eldreth, D. A., Cadet, J.-L., & Bolla, K. I. (2004) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2004.06.011 · Cited by 260 · see citing works

A quantitative evaluation of cross-participant registration techniques for MRI studies of the medial temporal lobe☆

Yassa, M. A., & Stark, C. E. L. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.09.016 · Cited by 252 · see citing works

Potency of Δ9–THC and Other Cannabinoids in Cannabis in England in 2005: Implications for Psychoactivity and Pharmacology*

Potter, D. J., Clark, P., & Brown, M. B. (2008) · Journal of Forensic Sciences · doi:10.1111/j.1556-4029.2007.00603.x · Cited by 230 · see citing works

A single in-vivo exposure to Δ9THC blocks endocannabinoid-mediated synaptic plasticity

Mato, S., Chevaleyre, V., Robbe, D., Pazos, Á., Castillo, P. E., & Manzoni, O. J. (2004) · Nature Neuroscience · doi:10.1038/nn1251 · Cited by 220 · see citing works

Brain size and grey matter volume in the healthy human brain.

Lüders, E., Steinmetz, H., & Jäncke, L. (2002) · PubMed · doi:10.1097/01.wnr.0000049603.85580.da · Cited by 208 · see citing works

Effects of frequent marijuana use on brain tissue volume and composition

Block, R. I., OʼLeary, D. S., Ehrhardt, J. C., Augustinack, J. C., Ghoneim, M. M., Arndt, S. V., & Hall, J. A. (2000) · Neuroreport · doi:10.1097/00001756-200002280-00013 · Cited by 182 · see citing works

Effects of frequent cannabis use on hippocampal activity during an associative memory task

Jager, G., van Hell, H. H., de Win, M. M. L., Kahn, R. S., van den Brink, W., van Ree, J. M., & Ramsey, N. F. (2006) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2006.10.003 · Cited by 176 · see citing works

Quantitative changes in hippocampal structure following long-term exposure to Δ9-tetrahydrocannabinol: possible mediation by glucocorticoid systems

Landfield, P. W., Cadwallader, L. B., & Vinsant, S. L. (1988) · Brain Research · doi:10.1016/0006-8993(88)91597-1 · Cited by 154 · see citing works

Dorsolateral Prefrontal Cortex N-Acetylaspartate/Total Creatine (NAA/tCr) Loss in Male Recreational Cannabis Users

Hermann, D., Sartorius, A., Welzel, H., Walter, S., Skopp, G., Ende, G., & Mann, K. F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.08.027 · Cited by 135 · see citing works

Lack of Hippocampal Volume Change in Long‐term Heavy Cannabis Users

Tzilos, G. K., Cintron, C. B., Wood, J. B. R., Simpson, N. S., Young, A. D., Pope, H. G., & Yurgelun-Todd, D. A. (2005) · American Journal on Addictions · doi:10.1080/10550490590899862 · Cited by 130 · see citing works

Cannabinoids Inhibit the Formation of New Synapses between Hippocampal Neurons in Culture

Kim, D., & Thayer, S. A. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-10-j0004.2001 · Cited by 127 · see citing works

Morphometric studies of the rat hippocampus following chronic delta-9-tetrahydrocannabinol (THC)

Scallet, A. C., Uemura, E., Andrews, A. M., Ali, S. F., McMillan, D. E., Paule, M. G., Brown, R. M., & Slikker, W. (1987) · Brain Research · doi:10.1016/0006-8993(87)91576-9 · Cited by 122 · see citing works

Deposition of cannabinoids in hair after long-term use of cannabis

Skopp, G., Strohbeck-Kuehner, P., Mann, K. F., & Hermann, D. (2006) · Forensic Science International · doi:10.1016/j.forsciint.2006.09.003 · Cited by 61 · see citing works

Selective regulation of dopamine transporter binding in the shell of the nucleus accumbens by adrenalectomy and corticosterone‐replacement

Sarnyai, Z., McKittrick, C. R., McEwen, B. S., & Kreek, M. J. (1998) · Synapse · doi:10.1002/(sici)1098-2396(199811)30:3 · Cited by 35 · see citing works

Chicken or egg?

Baumann, K. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2872 · Cited by 20 · see citing works

Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders

Campos, A. C., Moreira, F. A., Gomes, F. V., Del Bel, E. A., & Guimarães, F. S. (2012) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2011.0389 · Cited by 475 · see citing works

Cannabis and adolescent brain development.

Lubman, D. I., Cheetham, A., & Yücel, M. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.11.009 · Cited by 360 · see citing works

Translational investigation of the therapeutic potential of Cannabidiol (CBD): Toward a new age

Crippa, J. A., Guimarães, F. S., Campos, A. C., & Zuardi, A. W. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02009 · Cited by 308 · see citing works

Grey matter alterations associated with cannabis use: results of a VBM study in heavy cannabis users and healthy controls

Cousijn, J., Wiers, R. W., Ridderinkhof, K. R., van den Brink, W., Veltman, D. J., & Goudriaan, A. E. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.09.046 · Cited by 287 · see citing works

A systematic review of the antipsychotic properties of cannabidiol in humans

Iseger, T. A., & Bossong, M. G. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.01.033 · Cited by 261 · see citing works

Long-term effects of marijuana use on the brain

Filbey, F. M., Aslan, S., Calhoun, V. D., Spence, J. S., Damaraju, E., Caprihan, A., & Segall, J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1415297111 · Cited by 249 · see citing works

The Role of cannabinoids in neuroanatomic alterations in cannabis users.

Lorenzetti, V., Solowij, N., & Yücel, M. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.11.013 · Cited by 208 · see citing works

Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being

Morgan, C. J. A., Gardener, C., Schafer, G., Swan, S., Demarchi, C., Freeman, T. P., Warrington, P., Rupasinghe, I., Ramoutar, A., Tan, N., et al. (2012) · Psychological Medicine · doi:10.1017/s0033291711001322 · Cited by 195 · see citing works

Plastic and neuroprotective mechanisms involved in the therapeutic effects of cannabidiol in psychiatric disorders

Campos, A. C., Fogaça, M. V., Scarante, F. F., Joca, S. R. L., Sales, A. J., Gomes, F. V., Sonego, A. B., Rodrigues, N. S., Galve-Roperh, I., & Guimarães, F. S. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00269 · Cited by 175 · see citing works

Considering Cannabis: The Effects of Regular Cannabis Use on Neurocognition in Adolescents and Young Adults

Lisdahl, K. M., Wright, N. E., Medina-Kirchner, C., Maple, K. E., & Shollenbarger, S. (2014) · Current Addiction Reports · doi:10.1007/s40429-014-0019-6 · Cited by 160 · see citing works

Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse

Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148 · see citing works

Cannabis effects on brain structure, function, and cognition: considerations for medical uses of cannabis and its derivatives

Burggren, A. C., Shirazi, A., Ginder, N., & London, E. D. (2019) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2019.1634086 · Cited by 144 · see citing works

Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: possible involvement of 5HT1A receptors

Campos, A. C., Ferreira, F. R., & Guimarães, F. S. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.08.012 · Cited by 139 · see citing works

Cannabidiol normalizes caspase 3, synaptophysin, and mitochondrial fission protein DNM1L expression levels in rats with brain iron overload: implications for neuroprotection

da Silva, V. K., de Freitas, B. S., da Silva Dornelles, A., Nery, L. R., Falavigna, L., Ferreira, R. D. P., Bogo, M. R., Hallak, J. E. C., Zuardi, A. W., Crippa, J. A. S., et al. (2014) · Molecular Neurobiology · doi:10.1007/s12035-013-8514-7 · Cited by 91 · see citing works

Neuroimaging studies of acute effects of THC and CBD in humans and animals: a systematic review

Batalla, A., Crippa, J. A., Busatto, G. F., Guimaraes, F. S., Zuardi, A. W., Valverde, O., Atakan, Z., McGuire, P. K., Bhattacharyya, S., & Martín-Santos, R. (2014) · Current Pharmaceutical Design · doi:10.2174/13816128113199990432 · Cited by 91 · see citing works

Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders

Fagherazzi, E. V., Garcia, V. A., Maurmann, N., Bervanger, T., Halmenschlager, L. H., Busato, S. B., Hallak, J. E., Zuardi, A. W., Crippa, J. A., & Schröder, N. (2012) · Psychopharmacology · doi:10.1007/s00213-011-2449-3 · Cited by 87 · see citing works

Preliminary in vivo evidence of lower hippocampal synaptic density in cannabis use disorder

D’Souza, D. C., Radhakrishnan, R., Naganawa, M., Ganesh, S., Nabulsi, N., Najafzadeh, S., Ropchan, J., Ranganathan, M., Cortes-Briones, J., Huang, Y., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-020-00891-4 · Cited by 55 · see citing works

An overview on synthetic and biological activities of cannabidiol (CBD) and its derivatives

Wang, X., Zhang, H., Liu, Y., Yang, X., Yang, B., Li, H., & Chen, L. (2023) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2023.106810 · Cited by 57 · see citing works

Δ9-THC Intoxication by Cannabidiol-Enriched Cannabis Extract in Two Children with Refractory Epilepsy: Full Remission after Switching to Purified Cannabidiol

Crippa, J. A., Crippa, A. C. S., Hallak, J. E. C., Martín‐Santos, R., & Zuardi, A. W. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00359 · Cited by 71 · see citing works

Constituents of Cannabis Sativa L. II: Absence of Cannabidiol in an African Variant

Turner, C. E., & Hadley, K. W. (1973) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600620214 · Cited by 59 · see citing works

A role for cannabidiol in psychiatry? Keep calm and follow the drug development rules

Gobbi, G. (2019) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2019.1584680 · Cited by 3 · see citing works

Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis

Morgan, C. J., Freeman, T. P., Schafer, G. L., & Curran, H. V. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.58 · Cited by 196 · see citing works