Complex mechanics of the heterogeneous extracellular matrix in cancer

Angiogenesis in cancer and other diseases

Carmeliet, P., & Jain, R. K. (2000) · Nature · doi:10.1038/35025220 · Cited by 9,070 · see citing works

Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin

Aziz, J., Shezali, H., Radzi, Z., Yahya, N. A., Abu Kassim, N. H., Czernuszka, J., & Rahman, M. T. (2016) · Skin Pharmacology and Physiology · doi:10.1159/000447017 · Cited by 7,323 · see citing works

Tissue Cells Feel and Respond to the Stiffness of Their Substrate

Discher, D. E., Janmey, P., & Wang, Y.-L. (2005) · Science · doi:10.1126/science.1116995 · Cited by 6,382 · see citing works

New functions for the matrix metalloproteinases in cancer progression

Egeblad, M., & Werb, Z. (2002) · Nature Reviews Cancer · doi:10.1038/nrc745 · Cited by 6,108 · see citing works

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

Kessenbrock, K., Plaks, V., & Werb, Z. (2010) · Cell · doi:10.1016/j.cell.2010.03.015 · Cited by 5,151 · see citing works

Molecular Biology of the Cell

Alberts, B., Johnson, A. D., Lewis, J. H., RAFF, M. C., Roberts, K. J., & Walter, P. (2007) · W.W. Norton eBooks · doi:10.1201/9780203833445 · Cited by 4,591 · see citing works

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

Levental, K. R., Yu, H., Kass, L., Lakins, J. N., Egeblad, M., Erler, J. T., Fong, S. F. T., Csiszar, K., Giaccia, A., Weninger, W., et al. (2009) · Cell · doi:10.1016/j.cell.2009.10.027 · Cited by 4,101 · see citing works

Tensional homeostasis and the malignant phenotype

Paszek, M. J., Zahir, N., Johnson, K. R., Lakins, J. N., Rozenberg, G. I., Gefen, A., Reinhart-King, C. A., Margulies, S. S., Dembo, M., Boettiger, D., et al. (2005) · Cancer Cell · doi:10.1016/j.ccr.2005.08.010 · Cited by 3,941 · see citing works

Evidence for the Formation of Symmetric and Asymmetric DLPC-DAPC Lipid Bilayer Domains

Ritter, M., Schmidt, S., Jakab, M., Paulmichl, M., & Henderson, R. M. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350122 · Cited by 3,923 · see citing works

Cell Movement Is Guided by the Rigidity of the Substrate

Lo, C.-M., Wang, H.-B., Dembo, M., & Wang, Y.-L. (2000) · Biophysical Journal · doi:10.1016/s0006-3495(00)76279-5 · Cited by 3,289 · see citing works

Tumour-cell invasion and migration: diversity and escape mechanisms

Friedl, P., & Wolf, K. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1075 · Cited by 3,225 · see citing works

The extracellular matrix: A dynamic niche in cancer progression

Lu, P., Weaver, V. M., & Werb, Z. (2012) · Journal of Cell Biology · doi:10.1083/jcb.201102147 · Cited by 3,024 · see citing works

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

Balaban, N. Q., Schwarz, U. S., Riveline, D., Goichberg, P., Tzur, G., Sabanay, I., Mahalu, D., Safran, S. A., Bershadsky, A. D., Addadi, L., et al. (2001) · Nature Cell Biology · doi:10.1038/35074532 · Cited by 2,137 · see citing works

Cells lying on a bed of microneedles: An approach to isolate mechanical force

Tan, J. L., Tien, J., Pirone, D. M., Gray, D. S., Bhadriraju, K., & Chen, C. S. (2003) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.0235407100 · Cited by 2,036 · see citing works

The extracellular matrix modulates the hallmarks of cancer

Pickup, M. W., Mouw, J. K., & Weaver, V. M. (2014) · EMBO Reports · doi:10.15252/embr.201439246 · Cited by 2,014 · see citing works

SINGLE-PARTICLE TRACKING:Applications to Membrane Dynamics

Saxton, M. J., & Jacobson, K. (1997) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.26.1.373 · Cited by 1,810 · see citing works

Collagen reorganization at the tumor-stromal interface facilitates local invasion

Provenzano, P. P., Eliceiri, K. W., Campbell, J. M., Inman, D. R., White, J. G., & Keely, P. J. (2006) · BMC Medicine · doi:10.1186/1741-7015-4-38 · Cited by 1,804 · see citing works

Laminin–a glycoprotein from basement membranes

Timpl, R., Rohde, H., Robey, P. G., Rennard, S. I., Foidart, J. M., & Martin, G. R. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)83607-4 · Cited by 1,780 · see citing works

Nonlinear elasticity in biological gels

Storm, C., Pastore, J. J., MacKintosh, F. C., Lubensky, T. C., & Janmey, P. A. (2005) · Nature · doi:10.1038/nature03521 · Cited by 1,707 · see citing works

Matrigel: Basement membrane matrix with biological activity

Kleinman, H. K., & Martin, G. R. (2005) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2005.05.004 · Cited by 1,673 · see citing works

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

Cox, T. R., & Erler, J. T. (2011) · Disease Models & Mechanisms · doi:10.1242/dmm.004077 · Cited by 1,569 · see citing works

Extracellular Matrix Assembly: A Multiscale Deconstruction

Mouw, J. K., Ou, G., & Weaver, V. M. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3902 · Cited by 1,534 · see citing works

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

Erez, N., Truitt, M., Olson, P., & Hanahan, D. (2010) · Cancer Cell · doi:10.1016/j.ccr.2009.12.041 · Cited by 1,515 · see citing works

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

Calvo, F., Ege, N., Grande-Garcia, A., Hooper, S., Jenkins, R. P., Chaudhry, S. I., Harrington, K., Williamson, P., Moeendarbary, E., Charras, G., et al. (2013) · Nature Cell Biology · doi:10.1038/ncb2756 · Cited by 1,478 · see citing works

Compensation mechanism in tumor cell migration

Wolf, K., Mazo, I. B., Leung, H. C. H., Engelke, K., von Andrian, U. H., Deryugina, E. I., Strongin, A. Y., Bröcker, E., & Friedl, P. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200209006 · Cited by 1,392 · see citing works

Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force

Wolf, K., te Lindert, M., Krause, M., Alexander, S., te Riet, J., Willis, A. L., Hoffman, R. M., Figdor, C. G., Weiss, S. J., & Friedl, P. (2013) · Journal of Cell Biology · doi:10.1083/jcb.201210152 · Cited by 1,375 · see citing works

Collagen density promotes mammary tumor initiation and progression

Provenzano, P. P., Inman, D. R., Eliceiri, K. W., Knittel, J. G., Yan, L., Rueden, C., White, J. G., & Keely, P. J. (2008) · BMC Medicine · doi:10.1186/1741-7015-6-11 · Cited by 1,364 · see citing works

Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions

Hynes, R. O., & Naba, A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004903 · Cited by 1,349 · see citing works

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

Conklin, M. W., Eickhoff, J. C., Riching, K. M., Pehlke, C. A., Eliceiri, K. W., Provenzano, P. P., Friedl, A., & Keely, P. J. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2010.11.076 · Cited by 1,273 · see citing works

Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative

Daynes, R. A., Araneo, B. A., Ershler, W. B., Maloney, C., Li, G. Z., & Ryu, S. Y. (1993) · The Journal of Immunology · doi:10.4049/jimmunol.150.12.5219 · Cited by 1,264 · see citing works

The nanomechanical signature of breast cancer

Plodinec, M., Loparić, M., Monnier, C. A., Obermann, E. C., Zanetti‐Dällenbach, R., Oertle, P., Hyötylä, J. T., Aebi, U., Bentires‐Alj, M., Lim, R. Y. H., et al. (2012) · Nature Nanotechnology · doi:10.1038/nnano.2012.167 · Cited by 1,111 · see citing works

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

Acerbi, I., Cassereau, L., Dean, I. S., Shi, Q., Au, A., Park, C., Chen, Y. Y., Liphardt, J., Hwang, E. S., & Weaver, V. M. (2015) · Integrative Biology · doi:10.1039/c5ib00040h · Cited by 1,062 · see citing works

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

Akhmanova, A., & Steinmetz, M. O. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2369 · Cited by 1,047 · see citing works

The Role of Mechanical Forces in Tumor Growth and Therapy

Jain, R. K., Martin, J. D., & Stylianopoulos, T. (2014) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071813-105259 · Cited by 1,044 · cited 1× · see citing works

Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

Wolf, K., Wu, Y., Liu, Y., Geiger, J., Tam, E. M., Overall, C. M., Stack, M. S., & Friedl, P. (2007) · Nature Cell Biology · doi:10.1038/ncb1616 · Cited by 1,009 · see citing works

Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure

Chen, X., Nadiarynkh, O., Plotnikov, S., & Campagnola, P. J. (2012) · Nature Protocols · doi:10.1038/nprot.2012.009 · Cited by 985 · see citing works

Corneal structure and transparency

Meek, K. M., & Knupp, C. (2015) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2015.07.001 · Cited by 853 · see citing works

A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion

Labernadie, A., Kato, T., Brugués, A., Serra‐Picamal, X., Derzsi, S., Arwert, E. N., Weston, A., González-Tarragó, V., Elósegui-Artola, A., Albertazzi, L., et al. (2017) · Nature Cell Biology · doi:10.1038/ncb3478 · Cited by 747 · see citing works

Viscoelastic Retraction of Single Living Stress Fibers and Its Impact on Cell Shape, Cytoskeletal Organization, and Extracellular Matrix Mechanics

Kumar, S., Maxwell, I. Z., Heisterkamp, A., Polte, T. R., Lele, T. P., Salanga, M. C., Mazur, E., & Ingber, D. E. (2006) · Biophysical Journal · doi:10.1529/biophysj.105.071506 · Cited by 681 · see citing works

Measurement of mechanical tractions exerted by cells in three-dimensional matrices

Legant, W. R., Miller, J. S., Blakely, B. L., Cohen, D. M., Genin, G. M., & Chen, C. S. (2010) · Nature Methods · doi:10.1038/nmeth.1531 · Cited by 647 · see citing works

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

Laklai, H., Miroshnikova, Y. A., Pickup, M. W., Collisson, E. A., Kim, G., Barrett, A., Hill, R. C., Lakins, J. N., Schlaepfer, D. D., Mouw, J. K., et al. (2016) · Nature Medicine · doi:10.1038/nm.4082 · Cited by 598 · see citing works

Collagen fibrillogenesis <i>in vitro:</i> interaction of types I and V collagen regulates fibril diameter

Birk, D. E., Fitch, J. M., Babiarz, J. P., Doane, K. J., & Linsenmayer, T. F. (1990) · Journal of Cell Science · doi:10.1242/jcs.95.4.649 · Cited by 596 · see citing works

Matrix nanotopography as a regulator of cell function

Kim, D., Provenzano, P. P., Smith, C. L., & Levchenko, A. (2012) · The Journal of Cell Biology · doi:10.1083/jcb.201108062 · Cited by 576 · see citing works

Medical ultrasound: imaging of soft tissue strain and elasticity

Wells, P. N. T., & Liang, H. (2011) · Journal of The Royal Society Interface · doi:10.1098/rsif.2011.0054 · Cited by 543 · see citing works

Confocal Brillouin microscopy for three-dimensional mechanical imaging

Scarcelli, G., & Yun, S. H. (2007) · Nature Photonics · doi:10.1038/nphoton.2007.250 · Cited by 530 · see citing works

Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells

Rice, A. J., Cortes, E., Lachowski, D., Cheung, B. C. H., Karim, S. A., Morton, J. P., & Hernández, A. E. D. R. (2017) · Oncogenesis · doi:10.1038/oncsis.2017.54 · Cited by 526 · see citing works

Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch

Case, L. B., & Waterman, C. M. (2015) · Nature Cell Biology · doi:10.1038/ncb3191 · Cited by 520 · see citing works

Quantifying forces in cell biology

Roca‐Cusachs, P., Conte, V., & Trepat, X. (2017) · Nature Cell Biology · doi:10.1038/ncb3564 · Cited by 499 · see citing works

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

Provenzano, P. P., Inman, D. R., Eliceiri, K. W., Trier, S. M., & Keely, P. J. (2008) · Biophysical Journal · doi:10.1529/biophysj.108.133116 · Cited by 493 · see citing works

Solid stress and elastic energy as measures of tumour mechanopathology

Nia, H. T., Liu, H., Seano, G., Datta, M., Jones, D., Rahbari, N. N., Incio, J., Chauhan, V. P., Jung, K., Martin, J. D., et al. (2016) · Nature Biomedical Engineering · doi:10.1038/s41551-016-0004 · Cited by 452 · see citing works

Noncontact three-dimensional mapping of intracellular hydromechanical properties by Brillouin microscopy

Scarcelli, G., Polacheck, W. J., Nia, H. T., Patel, K., Grodzinsky, A. J., Kamm, R. D., & Yun, S. H. (2015) · Nature Methods · doi:10.1038/nmeth.3616 · Cited by 415 · see citing works

Physical State of the Extracellular Matrix Regulates the Structure and Molecular Composition of Cell-Matrix Adhesions

Katz, B., Zamir, E., Bershadsky, A. D., Kam, Z., Yamada, K. M., & Geiger, B. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.3.1047 · Cited by 413 · see citing works

Cellular Traction Stresses Increase with Increasing Metastatic Potential

Kraning-Rush, C. M., Califano, J. P., & Reinhart‐King, C. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032572 · Cited by 393 · see citing works

Strain-Induced Alignment in Collagen Gels

Vader, D., Kabla, A., Weitz, D. A., & Mahadevan, L. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005902 · Cited by 390 · see citing works

The microstructure and micromechanics of the tendon–bone insertion

Rossetti, L., Kuntz, L. A., Kunold, E., Schock, J., Müller, K. W., Grabmayr, H., Stolberg-Stolberg, J., Pfeiffer, F., Sieber, S. A., Burgkart, R., et al. (2017) · Nature Materials · doi:10.1038/nmat4863 · Cited by 390 · see citing works

On-chip human microvasculature assay for visualization and quantification of tumor cell extravasation dynamics

Chen, M. B., Whisler, J. A., Fröse, J., Yu, C., Shin, Y., & Kamm, R. D. (2017) · Nature Protocols · doi:10.1038/nprot.2017.018 · Cited by 385 · see citing works

Cancer cell detection in tissue sections using AFM

Lekka, M., Gil, D., Pogoda, K., Dulińska-Litewka, J., Jach, R., Gostek, J., Klymenko, O., Prauzner-Bechcicki, S., Stachura, Z., Wiltowska-Zuber, J., et al. (2011) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2011.12.013 · Cited by 369 · see citing works

Proteoglycan-collagen arrangements in developing rat tail tendon. An electron microscopical and biochemical investigation

Scott, J. E., Orford, C. R., & Hughes, E. W. (1981) · Biochemical Journal · doi:10.1042/bj1950573 · Cited by 345 · see citing works

Visualization and quantification of breast cancer biomechanical properties with magnetic resonance elastography.

Plewes, D., Bishop, J., Samani, A., & Sciarretta, J. (2000) · Physics in Medicine and Biology · doi:10.1088/0031-9155/45/6/314 · Cited by 338 · see citing works

Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels

Nam, S., Hu, K. H., Butte, M. J., & Chaudhuri, O. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1523906113 · Cited by 336 · see citing works

Signal transduction for chemotaxis and haptotaxis by matrix molecules in tumor cells.

Aznavoorian, S. A., Stracke, M. L., Krutzsch, H. C., Schiffmann, E., & Liotta, L. A. (1990) · The Journal of Cell Biology · doi:10.1083/jcb.110.4.1427 · Cited by 328 · see citing works

Three-dimensional force microscopy of cells in biopolymer networks

Steinwachs, J., Metzner, C., Skodzek, K., Lang, N. R., Thievessen, I., Mark, C., Münster, S., Aifantis, K. E., & Fabry, B. (2015) · Nature Methods · doi:10.1038/nmeth.3685 · Cited by 323 · see citing works

The elastic properties of elastin

Hoeve, C. A. J., & Flory, P. J. (1974) · Biopolymers · doi:10.1002/bip.1974.360130404 · Cited by 313 · see citing works

Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibers

Wang, H., Abhilash, A. S., Chen, C. S., Wells, R. G., & Shenoy, V. B. (2014) · Biophysical Journal · doi:10.1016/j.bpj.2014.09.044 · Cited by 313 · see citing works

MR Elastography of Liver Tumors: Preliminary Results

Venkatesh, S. K., Yin, M., Glockner, J. F., Takahashi, N., Araoz, P. A., Talwalkar, J. A., & Ehman, R. L. (2008) · American Journal of Roentgenology · doi:10.2214/ajr.07.3123 · Cited by 312 · see citing works

Cell contraction induces long-ranged stress stiffening in the extracellular matrix

Han, Y., Ronceray, P., Xu, G., Malandrino, A., Kamm, R. D., Lenz, M., Broedersz, C. P., & Guo, M. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1722619115 · Cited by 293 · see citing works

In situforce mapping of mammary gland transformation

Lopez, J. I., Kang, I., You, W., McDonald, D. M., & Weaver, V. M. (2011) · Integrative Biology · doi:10.1039/c1ib00043h · Cited by 284 · see citing works

Strain history dependence of the nonlinear stress response of fibrin and collagen networks

Münster, S., Jawerth, L. M., Leslie, B. A., Weitz, J. I., Fabry, B., & Weitz, D. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222787110 · Cited by 281 · see citing works

Nanometre-level analysis demonstrates that lipid flow does not drive membrane glycoprotein movements

Sheetz, M. P., Turney, S. G., Qian, H., & Elson, E. L. (1989) · Nature · doi:10.1038/340284a0 · Cited by 278 · see citing works

Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization

Colombelli, J., Besser, A., Kress, H., Reynaud, E. G., Girard, P. P., Caussinus, E., Haselmann, U., Small, J. V., Schwarz, U. S., & Stelzer, E. H. K. (2009) · Journal of Cell Science · doi:10.1242/jcs.042986 · Cited by 276 · see citing works

Engineering and physical sciences in oncology: challenges and opportunities

Mitchell, M. J., Jain, R. K., & Langer, R. (2017) · Nature Reviews Cancer · doi:10.1038/nrc.2017.83 · Cited by 273 · see citing works

Invasive Breast Cancer: Relationship between Shear-wave Elastographic Findings and Histologic Prognostic Factors

Evans, A. J., Whelehan, P., Thomson, K., McLean, D., Brauer, K., Purdie, C. A., Baker, L., Jordan, L. B., Rauchhaus, P., & Thompson, A. (2012) · Radiology · doi:10.1148/radiol.12111317 · Cited by 264 · see citing works

Quantitative micro-elastography: imaging of tissue elasticity using compression optical coherence elastography

Kennedy, K. M., Chin, L., McLaughlin, R. A., Latham, B. I., Saunders, C. M., Sampson, D. D., & Kennedy, B. F. (2015) · Scientific Reports · doi:10.1038/srep15538 · Cited by 263 · see citing works

Fibroblast contraction occurs on release of tension in attached collagen lattices: Dependency on an organized actin cytoskeleton and serum

Tomasek, J. J., Haaksma, C. J., Eddy, R. J., & Vaughan, M. B. (1992) · The Anatomical Record · doi:10.1002/ar.1092320305 · Cited by 246 · see citing works

Why the stroma matters in breast cancer

Conklin, M. W., & Keely, P. J. (2012) · Cell Adhesion & Migration · doi:10.4161/cam.20567 · Cited by 236 · see citing works

Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions

Fraley, S. I., Wu, P.-H., He, L., Feng, Y., Krishnamurthy, R., Longmore, G. D., & Wirtz, D. (2015) · Scientific Reports · doi:10.1038/srep14580 · Cited by 234 · see citing works

A Fast Iterative Digital Volume Correlation Algorithm for Large Deformations

Bar-Kochba, E., Toyjanova, J., Andrews, E. W., Kim, K., & Franck, C. (2014) · Experimental Mechanics · doi:10.1007/s11340-014-9874-2 · Cited by 231 · see citing works

Tendons and ligaments--an overview.

Benjamin, M., & Ralphs, J. R. (1997) · PubMed · Cited by 227 · see citing works

Single-cell response to stiffness exhibits muscle-like behavior

Mitrossilis, D., Fouchard, J., Guiroy, A., Desprat, N., Rodríguez, N., Fabry, B., & Asnacios, A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903994106 · Cited by 225 · see citing works

Measuring dynamic cell–material interactions and remodeling during 3D human mesenchymal stem cell migration in hydrogels

Schultz, K. M., Kyburz, K. A., & Anseth, K. S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1511304112 · Cited by 216 · see citing works

Mapping proteolytic cancer cell-extracellular matrix interfaces

Wolf, K., & Friedl, P. (2008) · Clinical & Experimental Metastasis · doi:10.1007/s10585-008-9190-2 · Cited by 211 · see citing works

Rheology and Confocal Reflectance Microscopy as Probes of Mechanical Properties and Structure during Collagen and Collagen/Hyaluronan Self-Assembly

Yang, Y., & Kaufman, L. J. (2009) · Biophysical Journal · doi:10.1016/j.bpj.2008.10.063 · Cited by 195 · see citing works

Dimensions in cell migration

Doyle, A. D., Petrie, R. J., Kutys, M. L., & Yamada, K. M. (2013) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2013.06.004 · Cited by 192 · see citing works

The emergence of ECM mechanics and cytoskeletal tension as important regulators of cell function

Peyton, S. R., Ghajar, C. M., Khatiwala, C. B., & Putnam, A. J. (2007) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-007-0004-y · Cited by 188 · see citing works

Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and MetastasisPreprint

Oudin, M. J., & Weaver, V. M. (2016) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2016.81.030817 · Cited by 188 · see citing works

High-Resolution Quantification of Focal Adhesion Spatiotemporal Dynamics in Living Cells

Berginski, M. E., Vitriol, E. A., Hahn, K. M., & Gomez, S. M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022025 · Cited by 180 · see citing works

Imaging matrix metalloproteinases in cancer

Scherer, R. L., McIntyre, J. O., & Matrisian, L. M. (2008) · Cancer and Metastasis Reviews · doi:10.1007/s10555-008-9152-9 · Cited by 162 · see citing works

Optical coherence micro-elastography: mechanical-contrast imaging of tissue microstructure

Kennedy, B. F., McLaughlin, R. A., Kennedy, K. M., Chin, L., Curatolo, A., Tien, A., Latham, B. I., Saunders, C. M., & Sampson, D. D. (2014) · Biomedical Optics Express · doi:10.1364/boe.5.002113 · Cited by 162 · see citing works

Control of 3-dimensional collagen matrix polymerization for reproducible human mammary fibroblast cell culture in microfluidic devices

Sung, K. E., Su, G., Pehlke, C. A., Trier, S. M., Eliceiri, K. W., Keely, P. J., Friedl, A., & Beebe, D. J. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.05.043 · Cited by 160 · see citing works

Mapping Local Matrix Remodeling Induced by a Migrating Tumor Cell Using Three-Dimensional Multiple-Particle Tracking

Bloom, R. J., George, J. P., Celedon, A., Sun, S. X., & Wirtz, D. (2008) · Biophysical Journal · doi:10.1529/biophysj.108.132738 · Cited by 158 · see citing works

Elucidation of the Roles of Tumor Integrin β1 in the Extravasation Stage of the Metastasis Cascade

Chen, M. B., Lamar, J. M., Li, R., Hynes, R. O., & Kamm, R. D. (2016) · Cancer Research · doi:10.1158/0008-5472.can-15-1325 · Cited by 158 · see citing works

Cancer Cell Stiffness: Integrated Roles of Three-Dimensional Matrix Stiffness and Transforming Potential

Baker, E. L., Lü, J., Yu, D., Bonnecaze, R. T., & Zaman, M. H. (2010) · Biophysical Journal · doi:10.1016/j.bpj.2010.07.051 · Cited by 153 · see citing works

Biomechanical properties of breast tissue, a state-of-the-art review

Ramião, N., Martins, P. A. L. D. S., Rynkevic, R., Fernandes, A. A., Barroso, M. L., & Santos, D. C. (2016) · Biomechanics and Modeling in Mechanobiology · doi:10.1007/s10237-016-0763-8 · Cited by 148 · see citing works

Preclinical intravital microscopy of the tumour-stroma interface: invasion, metastasis, and therapy response

Alexander, S., Weigelin, B., Winkler, F., & Friedl, P. (2013) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2013.07.001 · Cited by 145 · see citing works

Physico-mechanical aspects of extracellular matrix influences on tumorigenic behaviors

Cukierman, E., & Bassi, D. (2010) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2010.04.004 · Cited by 139 · see citing works

Biphasic response of cell invasion to matrix stiffness in three-dimensional biopolymer networks

Lang, N. R., Skodzek, K., Hurst, S., Mainka, A., Steinwachs, J., Schneider, J. R., Aifantis, K. E., & Fabry, B. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.11.003 · Cited by 137 · see citing works

Directed cell migration on fibronectin gradients: Effect of gradient slope

Smith, J. T., Elkin, J. T., & Reichert, W. M. (2006) · Experimental Cell Research · doi:10.1016/j.yexcr.2006.04.005 · Cited by 122 · see citing works

Microfabricated collagen tracks facilitate single cell metastatic invasion in 3D

Kraning-Rush, C. M., Carey, S. P., Lampi, M. C., & Reinhart‐King, C. A. (2013) · Integrative Biology · doi:10.1039/c3ib20196a · Cited by 118 · see citing works

Inter-Cellular Forces Orchestrate Contact Inhibition of Locomotion

Davis, J. R., Luchici, A., Mosis, F., Thackery, J., Salazar, J. A., Mao, Y., Dunn, G., Betz, T., Miodownik, M. A., & Stramer, B. M. (2015) · Cell · doi:10.1016/j.cell.2015.02.015 · Cited by 115 · see citing works

Tensile Forces Originating from Cancer Spheroids Facilitate Tumor Invasion

Kopanska, K. S., Alcheikh, Y., Staneva, R., Vignjevic, D. M., & Betz, T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0156442 · Cited by 112 · see citing works

Viscoelastic Imaging of Breast Tumor Microenvironment With Ultrasound

Insana, M. F., Pellot-Barakat, C. J. M., Sridhar, M., & Lindfors, K. K. (2004) · Journal of Mammary Gland Biology and Neoplasia · doi:10.1007/s10911-004-1409-5 · Cited by 110 · see citing works

Increased peri‐ductal collagen micro‐organization may contribute to raised mammographic density

McConnell, J. C., O’Connell, O. V., Brennan, K., Weiping, L., Howe, M., Joseph, L., Knight, D., O’Cualain, R., Lim, Y., Leek, A., et al. (2016) · Breast Cancer Research · doi:10.1186/s13058-015-0664-2 · Cited by 110 · see citing works

Elucidating mechanical transition effects of invading cancer cells with a subnucleus-scaled microfluidic serial dimensional modulation device

Mak, M., Reinhart‐King, C. A., & Erickson, D. (2012) · Lab on a Chip · doi:10.1039/c2lc41117b · Cited by 104 · see citing works

Second-harmonic generation imaging of cancer

Keikhosravi, A., Bredfeldt, J. S., Sagar, M. A. K., & Eliceiri, K. W. (2014) · Methods in cell biology · doi:10.1016/b978-0-12-420138-5.00028-8 · Cited by 102 · see citing works

Macrophage-Secreted TNFα and TGFβ1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways

Li, R., Hebert, J. D., Lee, T. A., Xing, H., Boussommier-Calleja, A., Hynes, R. O., Lauffenburger, D. A., & Kamm, R. D. (2017) · Cancer Research · doi:10.1158/0008-5472.can-16-0442 · Cited by 100 · see citing works

Extracellular matrix determinants and the regulation of cancer cell invasion stratagems

WILLIS, A. L., SABEH, F., LI, X. ‐., & WEISS, S. J. (2013) · Journal of Microscopy · doi:10.1111/jmi.12064 · Cited by 85 · see citing works

In Vitro Modeling of Mechanics in Cancer Metastasis

Malandrino, A., Kamm, R. D., & Moeendarbary, E. (2017) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.7b00041 · Cited by 78 · see citing works

Static and dynamic light scattering from aggregating particles

Bloomfield, V. A. (2000) · Biopolymers · doi:10.1002/1097-0282(200009)54:3 · Cited by 77 · see citing works

A serial micropipette microfluidic device with applications to cancer cell repeated deformation studies

Mak, M., & Erickson, D. (2013) · Integrative Biology · doi:10.1039/c3ib40128f · Cited by 72 · see citing works

Atomic force microscopy-based force measurements on animal cells and tissues

Gautier, H. O. B., Thompson, A. J., Achouri, S., Koser, D. E., Holtzmann, K., Moeendarbary, E., & Franze, K. (2015) · Methods in cell biology · doi:10.1016/bs.mcb.2014.10.005 · Cited by 70 · see citing works

Cell-Extracellular Matrix Interactions in Cancer

Zent, R., & Pozzi, A. (2010) · Springer eBooks · doi:10.1007/978-1-4419-0814-8 · Cited by 70 · see citing works

Inelastic behaviour of collagen networks in cell–matrix interactions and mechanosensation

Mohammadi, H., Arora, P. D., Simmons, C. A., Janmey, P. A., & McCulloch, C. A. (2014) · Journal of The Royal Society Interface · doi:10.1098/rsif.2014.1074 · Cited by 65 · see citing works

Mean deformation metrics for quantifying 3D cell–matrix interactions without requiring information about matrix material properties

Stout, D., Bar-Kochba, E., Estrada, J. B., Toyjanova, J., Kesari, H., Reichner, J. S., & Franck, C. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1510935113 · Cited by 65 · see citing works

Mechanical Properties of the Tumor Stromal Microenvironment Probed In Vitro and Ex Vivo by In Situ-Calibrated Optical Trap-Based Active Microrheology

Staunton, J. R., Vieira, W. D., Fung, K. L., Lake, R. G., Devine, A., & Tanner, K. (2016) · Cellular and Molecular Bioengineering · doi:10.1007/s12195-016-0460-9 · Cited by 63 · see citing works

A cytoskeletal clutch mediates cellular force transmission in a soft, three-dimensional extracellular matrix

Owen, L. M., Adhikari, A. S., Patel, M., Grimmer, P. W., Leijnse, N., Kim, M. C., Notbohm, J., Franck, C., & Dunn, A. R. (2017) · Molecular Biology of the Cell · doi:10.1091/mbc.e17-02-0102 · Cited by 63 · see citing works

Tumor suppressor protein SMAR1 modulates the roughness of cell surface: combined AFM and SEM study

Kaul-Ghanekar, R., Singh, S., Mamgain, H., Jalota‐Badhwar, A., Paknikar, K. M., & Chattopadhyay, S. (2009) · BMC Cancer · doi:10.1186/1471-2407-9-350 · Cited by 62 · see citing works

Selective changes in laminin adhesion and alpha 6 beta 4 integrin regulation are associated with the initial steps in keratinocyte maturation.

Tennenbaum, T., Li, L., Belanger, A. J., Luca, L. M. D., & Yuspa, S. H. (1996) · PubMed · Cited by 61 · see citing works

In vivo tissue has non-linear rheological behavior distinct from 3D biomimetic hydrogels, as determined by AMOTIV microscopy

Blehm, B. H., Devine, A., Staunton, J. R., & Tanner, K. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.12.019 · Cited by 59 · see citing works

Do cancer cells have distinct adhesions in 3D collagen matrices and in vivo?

Geraldo, S., Simon, A., Elkhatib, N., Louvard, D., Fetler, L., & Vignjevic, D. M. (2012) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2012.07.005 · Cited by 55 · see citing works

Laminin Levels Regulate Tissue Migration and Anterior-Posterior Polarity during Egg Morphogenesis in Drosophila

de la Loza, M. C. D., Díaz-Torres, A., Zurita, F., Rosales‐Nieves, A. E., Moeendarbary, E., Franze, K., Martin-Bermudo, M. D., & González‐Reyes, A. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.06.031 · Cited by 55 · see citing works

In vivo Quantification of the Structural Changes of Collagens in a Melanoma Microenvironment with Second and Third Harmonic Generation Microscopy

Wu, P., Hsieh, T., Tsai, Z.-U., & Liu, T. (2015) · Scientific Reports · doi:10.1038/srep08879 · Cited by 48 · see citing works

Quantitative analysis of 3D extracellular matrix remodelling by pancreatic stellate cells

Robinson, B. K., Cortés, E., Rice, A. J., Sarper, M., & Hernández, A. E. D. R. (2016) · Biology Open · doi:10.1242/bio.017632 · Cited by 46 · see citing works

Determination of Elastic Properties of Resected Human Breast Tissue Samples Using Optical Coherence Tomographic Elastography

Srivastava, A., Verma, Y., Rao, K. D., & Gupta, P. K. (2009) · Strain · doi:10.1111/j.1475-1305.2009.00627.x · Cited by 37 · see citing works

Atomic Force Microscopy Probing of Cancer Cells and Tumor Microenvironment Components

Stylianou, A., & Stylianopoulos, T. (2015) · BioNanoScience · doi:10.1007/s12668-015-0187-4 · Cited by 35 · see citing works

Optical-Based Analysis of Soft Tissue Structures

Goth, W., Lesicko, J., Sacks, M. S., & Tunnell, J. W. (2016) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071114-040625 · Cited by 33 · see citing works

Simulation of integrin-cytoskeletal interactions in migrating fibroblasts

Schmidt, C. E., Chen, T., & Lauffenburger, D. A. (1994) · Biophysical Journal · doi:10.1016/s0006-3495(94)80502-8 · Cited by 31 · see citing works

Poroelastic modeling of the intervertebral disc: A path toward integrated studies of tissue biophysics and organ degeneration

Malandrino, A., Jackson, A. R., Huyghe, J. M., & Noailly, J. (2015) · MRS Bulletin · doi:10.1557/mrs.2015.68 · Cited by 29 · see citing works

Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization

Colombelli, J., Besser, A., Kress, H., Reynaud, E. G., Girard, P., Caussinus, E., Haselmann, U., Small, J. V., Schwarz, U. S., & Stelzer, E. H. K. (2009) · Journal of Cell Science · doi:10.1242/jcs.054577 · Cited by 25 · see citing works

Mechanical decision trees for investigating and modulating single-cell cancer invasion dynamics

Mak, M., & Erickson, D. (2013) · Lab on a Chip · doi:10.1039/c3lc51173a · Cited by 22 · see citing works

Long-term Intravital Immunofluorescence Imaging of Tissue Matrix Components with Epifluorescence and Two-photon Microscopy

Güç, E., Fankhauser, M., Lund, A. W., Swartz, M. A., & Kilarski, W. W. (2014) · Journal of Visualized Experiments · doi:10.3791/51388 · Cited by 21 · see citing works

Relative Stiffness Measurements of Tumour Tissues by Shear Rheology

Madsen, C. D., & Cox, T. R. (2017) · BIO-PROTOCOL · doi:10.21769/bioprotoc.2265 · Cited by 19 · see citing works

Three-Dimensional Traction Force Microscopy of Engineered Epithelial Tissues

Piotrowski-Daspit, A. S., Varner, V. D., Gjorevski, N., & Nelson, C. M. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1164-6_13 · Cited by 17 · see citing works

Elasticity-based identification of tumor margins using Brillouin spectroscopy

Troyanova-Wood, M. A., Meng, Z., & Yakovlev, V. V. (2016) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.2213268 · Cited by 15 · see citing works

Tendons and ligaments

Riley, G. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-09138-1.00007-3 · Cited by 1 · see citing works

Crosstalk between cancer‐associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives

Mao, X., Xu, J., Wang, W., Liang, C., Hua, J., Liu, J., Zhang, B., Meng, Q., Yu, X., & Shi, S. (2021) · Molecular Cancer · doi:10.1186/s12943-021-01428-1 · Cited by 2,290 · see citing works

The matrix in cancer

Cox, T. R. (2021) · Nature reviews. Cancer · doi:10.1038/s41568-020-00329-7 · Cited by 978 · see citing works

Cancer-associated fibroblasts as abettors of tumor progression at the crossroads of EMT and therapy resistance

Fiori, M. E., Franco, S. D., Villanova, L., Bianca, P., Stassi, G., & Maria, R. D. (2019) · Molecular Cancer · doi:10.1186/s12943-019-0994-2 · Cited by 648 · see citing works

Matrix Metalloproteinases Shape the Tumor Microenvironment in Cancer Progression

Niland, S., Riscanevo, A. X., & Eble, J. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010146 · Cited by 528 · see citing works

Towards organoid culture without Matrigel

Kozlowski, M. T., Crook, C. J., & Ku, H. T. (2021) · Communications Biology · doi:10.1038/s42003-021-02910-8 · Cited by 409 · see citing works

Collagen in tendon, ligament, and bone healing. A current review.

Liu, S. H., Yang, R. S., Al-Shaikh, R. A., & Lane, J. M. (1995) · PubMed · Cited by 322 · see citing works

The matrix environmental and cell mechanical properties regulate cell migration and contribute to the invasive phenotype of cancer cells

Mierke, C. T. (2019) · Reports on Progress in Physics · doi:10.1088/1361-6633/ab1628 · Cited by 262 · see citing works

The mechanics of fibrillar collagen extracellular matrix

Sun, B. (2021) · Cell Reports Physical Science · doi:10.1016/j.xcrp.2021.100515 · Cited by 216 · see citing works

The role of extracellular matrix in biomechanics and its impact on bioengineering of cells and 3D tissues

Urbanczyk, M., Layland, S. L., & Schenke‐Layland, K. (2019) · Matrix Biology · doi:10.1016/j.matbio.2019.11.005 · Cited by 197 · see citing works

Metabolic heterogeneity in cancer

Demicco, M., Liu, X., Leithner, K., & Fendt, S. (2024) · Nature Metabolism · doi:10.1038/s42255-023-00963-z · Cited by 183 · see citing works

Extracellular matrix physical properties govern the diffusion of nanoparticles in tumor microenvironment

He, X., Yang, Y., Han, Y., Cao, C., Zhang, Z., Li, L., Xiao, C., Guo, H., Wang, L., Han, L., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2209260120 · Cited by 155 · see citing works

Decellularized Extracellular Matrix for Bioengineering Physiomimetic 3D in Vitro Tumor Models

Ferreira, L. P., Gaspar, V. M., & Mano, J. F. (2020) · Trends in Biotechnology · doi:10.1016/j.tibtech.2020.04.006 · Cited by 153 · see citing works

Tumor-derived small extracellular vesicles in cancer invasion and metastasis: molecular mechanisms, and clinical significance

Zhang, C., Qin, C., Dewanjee, S., Bhattacharya, H., Chakraborty, P., Jha, N. K., Gangopadhyay, M., Jha, S. K., & Liu, Q. (2024) · Molecular Cancer · doi:10.1186/s12943-024-01932-0 · Cited by 133 · see citing works

Spatiotemporal changes in mechanical matrisome components of the human ovary from prepuberty to menopause

Ouni, E., Bouzin, C., Dolmans, M., Marbaix, É., Ruys, S. P. D., Vertommen, D., & Amorim, C. A. (2020) · Human Reproduction · doi:10.1093/humrep/deaa100 · Cited by 132 · see citing works

Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine

Xin, Y., Li, K., Huang, M. L., Liang, C., Siemann, D. W., Wu, L., Tan, Y., & Tang, X. (2023) · Oncogene · doi:10.1038/s41388-023-02844-x · Cited by 125 · see citing works

Unravelling cell migration: defining movement from the cell surface

Merino-Casallo, F., Gómez‐Benito, M. J., Hervás-Raluy, S., & García‐Aznar, J. M. (2022) · Cell Adhesion & Migration · doi:10.1080/19336918.2022.2055520 · Cited by 114 · see citing works

Recent advances in regenerative medicine strategies for cancer treatment

Mansouri, V., Beheshtizadeh, N., Gharibshahian, M., Sabouri, L., Varzandeh, M., & Rezaei, N. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111875 · Cited by 112 · see citing works

3D Cancer Models: The Need for a Complex Stroma, Compartmentalization and Stiffness

Pape, J., Emberton, M., & Cheema, U. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.660502 · Cited by 98 · see citing works

3D In Vitro Models for Investigating the Role of Stiffness in Cancer Invasion

Micalet, A., Moeendarbary, E., & Cheema, U. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c01530 · Cited by 97 · see citing works

The use of mixed collagen-Matrigel matrices of increasing complexity recapitulates the biphasic role of cell adhesion in cancer cell migration: ECM sensing, remodeling and forces at the leading edge of cancer invasion

Anguiano, M., Morales, X., Castilla, C., Rodríguez‐Pena, A., Ederra, C., Martı́nez, M., Ariz, M., Esparza, M., Amaveda, H., Mora, M., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0220019 · Cited by 92 · see citing works

Modifying the Tumour Microenvironment: Challenges and Future Perspectives for Anticancer Plasma Treatments

Privat‐Maldonado, A., Bengtson, C., Razzokov, J., Smits, E., & Bogaerts, A. (2019) · Cancers · doi:10.3390/cancers11121920 · Cited by 87 · see citing works

Mechanical signatures in cancer metastasis

Agrawal, A., Javanmardi, Y., Watson, S. A., Serwinski, B., Djordjevic, B., Li, W., Aref, A. R., Jenkins, R. W., & Moeendarbary, E. (2025) · npj Biological Physics and Mechanics. · doi:10.1038/s44341-024-00007-x · Cited by 85 · see citing works

Mechanical forces in the tumor microenvironment: roles, pathways, and therapeutic approaches

Zhang, Y., Fu, Q., Sun, W., Yue, Q., He, P., Niu, D., & Zhang, M. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06306-8 · Cited by 83 · see citing works

Mimicking the Natural Basement Membrane for Advanced Tissue Engineering

Jain, P., Rauer, S. B., Möller, M., & Singh, S. (2022) · Biomacromolecules · doi:10.1021/acs.biomac.2c00402 · Cited by 82 · see citing works

Identifying cancer-associated fibroblasts as emerging targets for hepatocellular carcinoma

Zhang, J., Gu, C., Song, Q., Zhu, M., Xu, Y., Xiao, M., & Zheng, W. (2020) · Cell & Bioscience · doi:10.1186/s13578-020-00488-y · Cited by 78 · see citing works

Addressing Patient Specificity in the Engineering of Tumor Models

Bray, L. J., Hutmacher, D. W., & Bock, N. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00217 · Cited by 76 · see citing works

Mechanical Cues Affect Migration and Invasion of Cells From Three Different Directions

Mierke, C. T. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.583226 · Cited by 75 · see citing works

Collagen stiffness promoted non-muscle-invasive bladder cancer progression to muscle-invasive bladder cancer

Zhu, H.-E., Chen, H., Wang, J., Zhou, L., & Liu, S. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s194568 · Cited by 75 · see citing works

Tissue Rheology as a Possible Complementary Procedure to Advance Histological Diagnosis of Colon Cancer

Deptuła, P., Łysik, D., Pogoda, K., Cieśluk, M., Namiot, A., Mystkowska, J., Król, G., Głuszek, S., Janmey, P. A., & Bucki, R. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c00975 · Cited by 74 · see citing works

The role of extracellular matrix viscoelasticity in development and disease

Courbot, O., & Elósegui-Artola, A. (2025) · npj Biological Physics and Mechanics. · doi:10.1038/s44341-025-00014-6 · Cited by 73 · see citing works

Exploring the clinical value of tumor microenvironment in platinum-resistant ovarian cancer

Ghoneum, A., Almousa, S., Warren, B., Abdulfattah, A. Y., Shu, J., Abouelfadl, H., Gonzalez, D., Livingston, C., & Said, N. A. (2021) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.12.024 · Cited by 72 · see citing works

Recent Trends in In Situ Enzyme-Activatable Prodrugs for Targeted Cancer Therapy

Sun, I., Yoon, H. Y., Lim, D., & Kim, K. (2020) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.0c00082 · Cited by 68 · see citing works

Metastasis: crosstalk between tissue mechanics and tumour cell plasticity

Coban, B., Bergonzini, C., Zweemer, A. J. M., & Danen, E. H. J. (2020) · British Journal of Cancer · doi:10.1038/s41416-020-01150-7 · Cited by 62 · see citing works

Nattokinase-Mediated Regulation of Tumor Physical Microenvironment to Enhance Chemotherapy, Radiotherapy, and CAR-T Therapy of Solid Tumor

Zhang, Y., Pei, P., Zhou, H., Xie, Y., Yang, S., Shen, W., Hu, L. T., Zhang, Y., Liu, T., & Yang, K. (2023) · ACS Nano · doi:10.1021/acsnano.2c12463 · Cited by 62 · see citing works

For and against tumor microenvironment: Nanoparticle-based strategies for active cancer therapy

Karimi, S., Bakhshali, R., Bolandi, S., Zahed, Z., Zadeh, S. S. M., Zenjanab, M. K., & Jahanban‐Esfahlan, R. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.101626 · Cited by 60 · see citing works

Spatiotemporally Super-Resolved Volumetric Traction Force Microscopy

Colin‐York, H., Javanmardi, Y., Barbieri, L., Li, D., Korobchevskaya, K., Guo, Y., Hall, C. M., Taylor, A., Khuon, S., Sheridan, G. K., et al. (2019) · Nano Letters · doi:10.1021/acs.nanolett.9b01196 · Cited by 60 · see citing works

Influence of elastomeric matrix and particle volume fraction on the mechanical response of magneto-active polymers

Garcia‐Gonzalez, D., Moreno, M. Á., Valencia, L., Árias, A., & Velasco, D. (2021) · Composites Part B Engineering · doi:10.1016/j.compositesb.2021.108796 · Cited by 60 · see citing works

Organotypic 3D decellularized matrix tumor spheroids for high-throughput drug screening

Ferreira, L. P., Gaspar, V. M., Mendes, L., Duarte, I. F., & Mano, J. F. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120983 · Cited by 59 · see citing works

Engineering extracellular matrix to improve drug delivery for cancer therapy

He, X., Yang, Y., Li, L., Zhang, P., Guo, H., Liu, N., Yang, X., & Xu, F. (2020) · Drug Discovery Today · doi:10.1016/j.drudis.2020.06.029 · Cited by 54 · see citing works

First-in-human in vivo non-invasive assessment of intra-tumoral metabolic heterogeneity in renal cell carcinoma

Tran, M. G. B., Latifoltojar, A., Neves, J. B., Papoutsaki, M., Gong, F., Comment, A., Costa, A. S. H., Glaser, M., Tran‐Dang, M., Sheikh, S. E., et al. (2019) · BJR|case reports · doi:10.1259/bjrcr.20190003 · Cited by 53 · see citing works

The functional cross talk between cancer cells and cancer associated fibroblasts from a cancer mechanics perspective

Ansardamavandi, A., & Tafazzoli‐Shadpour, M. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2021.119103 · Cited by 52 · see citing works

Matrix stiffness regulates microvesicle-induced fibroblast activation

Schwager, S. C., Bordeleau, F., Zhang, J., Antonyak, M. A., Cerione, R. A., & Reinhart-King, C. A. (2019) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00418.2018 · Cited by 50 · see citing works

Role of tumour-derived exosomes in metastasis

Bai, S., Wei, Y., Liu, R., Xu, R., Li, X., & Du, J. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.112657 · Cited by 48 · see citing works

Cancer Mechanobiology: Microenvironmental Sensing and Metastasis

Lee, G., Han, S., Lee, J., Kim, H., & Kim, D. (2019) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.8b01230 · Cited by 46 · see citing works

Immunologic and immunogenomic aspects of tumor progression

Ladányi, A., & Tı́már, J. (2019) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2019.08.011 · Cited by 41 · see citing works

Oncomatrix: Molecular Composition and Biomechanical Properties of the Extracellular Matrix in Human Tumors

Klabukov, I., Smirnova, A., Yakimova, A. O., Kabakov, A. E., Atiakshin, D., Petrenko, D. А., Shestakova, V. A., Sulina, Y. Y., Yatsenko, E., Stepanenko, V. N., et al. (2024) · Journal of Molecular Pathology · doi:10.3390/jmp5040029 · Cited by 40 · see citing works

General cellular durotaxis induced with cell-scale heterogeneity of matrix-elasticity

Ebata, H., Moriyama, K., Kuboki, T., & Kidoaki, S. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119647 · Cited by 39 · see citing works

Triangular correlation (TrC) between cancer aggressiveness, cell uptake capability, and cell deformability

Brill‐Karniely, Y., Dror, D., Duanis‐Assaf, T., Goldstein, Y., Schwob, O., Millo, T., Orehov, N., Stern, T., Jaber, M., Loyfer, N., et al. (2020) · Science Advances · doi:10.1126/sciadv.aax2861 · Cited by 37 · see citing works

Mechanobiology of the female reproductive system

Matsuzaki, S. (2021) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12404 · Cited by 37 · see citing works

Extracellular matrix (ECM)-inspired high-strength gelatin-alginate based hydrogels for bone repair

Wu, T., Liu, L., Gao, Z., Cui, C., Fan, C., Liu, Y., Di, M., Yang, Q., Xu, Z., & Liu, W. (2023) · Biomaterials Science · doi:10.1039/d3bm00213f · Cited by 35 · see citing works

Mechanical and Systems Biology of Cancer

Spill, F., Bakal, C., & Mak, M. (2018) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2018.07.002 · Cited by 34 · see citing works

Impact of crosslink heterogeneity on extracellular matrix mechanics and remodeling

Mak, M. (2020) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2020.11.038 · Cited by 34 · see citing works

3D printed tissue models: From hydrogels to biomedical applications

Cadamuro, F., Nicotra, F., & Russo, L. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.01.048 · Cited by 34 · see citing works

Combination Therapy of Lox Inhibitor and Stimuli‐Responsive Drug for Mechanochemically Synergistic Breast Cancer Treatment

Zhu, S., Zhang, T., Gao, H., Jin, G., Yang, J., He, X., Guo, H., & Xu, F. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202300103 · Cited by 33 · see citing works

Phenotypic Heterogeneity, Bidirectionality, Universal Cues, Plasticity, Mechanics, and the Tumor Microenvironment Drive Cancer Metastasis

Mierke, C. T. (2024) · Biomolecules · doi:10.3390/biom14020184 · Cited by 32 · see citing works

Tumour growth: An approach to calibrate parameters of a multiphase porous media model based on in vitro observations of Neuroblastoma spheroid growth in a hydrogel microenvironment

Hervás-Raluy, S., Wirthl, B., Guerrero, P. E., Rei, G. R., Nitzler, J., Coronado, E., de Mora, J. F., Schrefler, B. A., Gómez‐Benito, M. J., García‐Aznar, J. M., et al. (2023) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2023.106895 · Cited by 31 · see citing works

Understanding the biology and advent of physics of cancer with perspicacity in current treatment therapy

Korgaonkar, N., & Yadav, K. S. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.117060 · Cited by 30 · see citing works

Breast Tumor Microenvironment: Emerging target of therapeutic phytochemicals

Malla, R. R., Deepak, K. G. K., Merchant, N., & Dasari, V. R. (2020) · Phytomedicine · doi:10.1016/j.phymed.2020.153227 · Cited by 30 · see citing works

Application of 3-D Microfluidic Models for Studying Mass Transport Properties of the Tumor Interstitial Matrix

Avendano, A., Cortes-Medina, M. G., & Song, J. W. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00006 · Cited by 29 · see citing works

Recursive feedback between matrix dissipation and chemo-mechanical signaling drives oscillatory growth of cancer cell invadopodia

Gong, Z., Wisdom, K. M., McEvoy, E., Chang, J., Adebowale, K., Price, C. C., Chaudhuri, O., & Shenoy, V. B. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109047 · Cited by 29 · see citing works

Aqueous Two‐Phase Emulsion Bioresin for Facile One‐Step 3D Microgel‐Based Bioprinting

Wang, Q., Karadaş, Ö., Backman, O., Wang, L., Näreoja, T., Rosenholm, J. M., Xu, C., & Wang, X. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202203243 · Cited by 29 · see citing works

Mechanobiology in oncology: basic concepts and clinical prospects

Chen, M. B., Javanmardi, Y., Shahreza, S., Serwinski, B., Aref, A. R., Djordjevic, B., & Moeendarbary, E. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1239749 · Cited by 28 · see citing works

Local soft niches in mechanically heterogeneous primary tumors promote brain metastasis via mechanotransduction-mediated HDAC3 activity

Tang, K., Zheng, Y., Hu, G., Xin, Y., Li, K., Zhang, C., Chen, X., Zhang, B., Li, X., Hu, B., et al. (2025) · Science Advances · doi:10.1126/sciadv.adq2881 · Cited by 28 · see citing works

Magnetic probe-based microrheology reveals local softening and stiffening of 3D collagen matrices by fibroblasts

Pokki, J., Zisi, I., Schulman, E., Indana, D., & Chaudhuri, O. (2021) · Biomedical Microdevices · doi:10.1007/s10544-021-00547-2 · Cited by 27 · see citing works

Collective Cell Migration in a Fibrous Environment: A Hybrid Multiscale Modelling Approach

Suveges, S., Chamseddine, I. M., Rejniak, K. A., Eftimie, R., & Trucu, D. (2021) · Frontiers in Applied Mathematics and Statistics · doi:10.3389/fams.2021.680029 · Cited by 27 · see citing works

Biophysical and mechanobiological considerations for T-cell-based immunotherapy

Zhuang, C., Gould, J. E., Enninful, A., Shao, S., & Mak, M. (2023) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2023.03.007 · Cited by 27 · see citing works

Evaluating the Impact of a Biomimetic Mechanical Environment on Cancer Invasion and Matrix Remodeling

Micalet, A., Pape, J., Bakkalci, D., Javanmardi, Y., Hall, C. M., Cheema, U., & Moeendarbary, E. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202201749 · Cited by 26 · see citing works

Recent advances in 3D bioprinted tumor models for personalized medicine

Gnatowski, P., Piłat, E., Kucińska‐Lipka, J., Saeb, M. R., Hamblin, M. R., & Mozafari, M. (2023) · Translational Oncology · doi:10.1016/j.tranon.2023.101750 · Cited by 26 · see citing works

Drug Delivery Systems for Overcoming Physical Barriers in Cancer Therapy

Yi, X., Jin, X., Hu, Y., Shen, Z., Zheng, X., Luo, D., Xu, T., Yan, J., & Huang, P. C. (2025) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.5c00474 · Cited by 25 · see citing works

Factor XIII and Fibrin Clot Properties in Acute Venous Thromboembolism

Ząbczyk, M., Natorska, J., & Undas, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22041607 · Cited by 25 · see citing works

ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer

Hoang, V. T., Matossian, M. D., Uçar, D. A., Elliott, S. G., La, J., Wright, M. K., Burks, H. E., Perles, A., Hossain, F. M., King, C. T., et al. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.01164 · Cited by 24 · see citing works

3D Traction Force Microscopy in Biological Gels: From Single Cells to Multicellular Spheroids

Cheung, B. C. H., Abbed, R. J., Wu, M., & Leggett, S. E. (2024) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-103122-031130 · Cited by 23 · see citing works

Characterization of multicellular breast tumor spheroids using image data-driven biophysical mathematical modeling

Bowers, H. J., Fannin, E. E., Thomas, A., & Weis, J. A. (2020) · Scientific Reports · doi:10.1038/s41598-020-68324-4 · Cited by 23 · see citing works

Computational insights into the influence of substrate stiffness on collective cell migration

Garcia‐Gonzalez, D., & Muñoz‐Barrutia, A. (2020) · Extreme Mechanics Letters · doi:10.1016/j.eml.2020.100928 · Cited by 23 · see citing works

Coupling Microfluidic Platforms, Microfabrication, and Tissue Engineered Scaffolds to Investigate Tumor Cells Mechanobiology

Millet, M., Messaoud, R. B., Luthold, C., & Bordeleau, F. (2019) · Micromachines · doi:10.3390/mi10060418 · Cited by 22 · see citing works

Spatial Regulation of Mitochondrial Heterogeneity by Stromal Confinement in Micropatterned Tumor Models

Begum, H. M., Ta, H. P., Zhou, H., Ando, Y., Kang, D. S., Nemes, K., Mariano, C. F., Hao, J., Yu, M., & Shen, K. (2019) · Scientific Reports · doi:10.1038/s41598-019-47593-8 · Cited by 22 · see citing works

Tumour Initiation: a Discussion on Evidence for a “Load-Trigger” Mechanism

Evans, J. J., Alkaisi, M. M., & Sykes, P. H. (2019) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-019-00888-z · Cited by 20 · see citing works

Intratumoral heterogeneity of second-harmonic generation scattering from tumor collagen and its effects on metastatic risk prediction

Desa, D. E., Strawderman, R. L., Wu, W., Hill, R. L., Smid, M., Martens, J. W. M., Turner, B. M., & Brown, E. B. (2020) · BMC Cancer · doi:10.1186/s12885-020-07713-4 · Cited by 20 · see citing works

The mechanobiology of NK cells- ‘Forcing NK to Sense’ target cells

Wong, D. C. P., & Ding, J. L. (2023) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2023.188860 · Cited by 20 · see citing works

Poroelastic model parameter identification using artificial neural networks: on the effects of heterogeneous porosity and solid matrix Poisson ratio

Dehghani, H., & Zilian, A. (2020) · Computational Mechanics · doi:10.1007/s00466-020-01868-4 · Cited by 20 · see citing works

Nephronectin as a Matrix Effector in Cancer

Magnussen, S. N., Toraskar, J., Hadler‐Olsen, E., Steigedal, T. S., & Svineng, G. (2021) · Cancers · doi:10.3390/cancers13050959 · Cited by 20 · see citing works

Advanced mechanotherapy: Biotensegrity for governing metastatic tumor cell fate via modulating the extracellular matrix

Abdollahiyan, P., Oroojalian, F., Baradaran, B., de la Guárdia, M., & Mokhtarzadeh, A. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.06.002 · Cited by 19 · see citing works

Engineering Heterogeneous Tumor Models for Biomedical Applications

Wu, Z., Huang, D., Wang, J., Zhao, Y., Sun, W., & Shen, X. (2023) · Advanced Science · doi:10.1002/advs.202304160 · Cited by 19 · see citing works

SRPX2 promotes cell proliferation and invasion via activating FAK/SRC/ERK pathway in non-small cell lung cancer

Li, X., Liu, J., Sun, H., Zou, Y., Chen, J., Chen, Y., Chen, C., & Wu, X. (2020) · Acta Biochimica Polonica · doi:10.18388/abp.2020_5158 · Cited by 19 · see citing works

Nanoscale Tracking Combined with Cell-Scale Microrheology Reveals Stepwise Increases in Force Generated by Cancer Cell Protrusions

Sikic, L., Schulman, E., Kosklin, A., Saraswathibhatla, A., Chaudhuri, O., & Pokki, J. (2022) · Nano Letters · doi:10.1021/acs.nanolett.2c01327 · Cited by 19 · see citing works

Real-time imaging of nanobubble ultrasound contrast agent flow, extravasation, and diffusion through an extracellular matrix using a microfluidic model

Cooley, M. B., Wulftange, W. J., Wegierak, D., Goreke, U., Abenojar, E., Gurkan, U. A., & Exner, A. A. (2023) · Lab on a Chip · doi:10.1039/d3lc00514c · Cited by 18 · see citing works

Modeling multiple taxis: Tumor invasion with phenotypic heterogeneity, haptotaxis, and unilateral interspecies repellence

Kolbe, N., Sfakianakis, N., Stinner, C., Surulescu, C., & Lenz, J. (2020) · Discrete and Continuous Dynamical Systems - B · doi:10.3934/dcdsb.2020284 · Cited by 18 · see citing works

Complexity of Tumor Microenvironment: Therapeutic Role of Curcumin and Its Metabolites

Prasad, S., Saha, P., Chatterjee, B., Chaudhary, A. A., Lall, R., & Srivastava, A. K. (2022) · Nutrition and Cancer · doi:10.1080/01635581.2022.2096909 · Cited by 17 · see citing works

Cancer Stem Cell Microenvironment Models with Biomaterial Scaffolds In Vitro

Hassan, G., Afify, S. M., Kitano, S., Seno, A., Ishii, H., Shang, Y., Matsusaki, M., & Seno, M. (2020) · Processes · doi:10.3390/pr9010045 · Cited by 17 · see citing works

Quantitative atlas of collagen hydrogels reveals mesenchymal cancer cell traction adaptation to the matrix nanoarchitecture

Blázquez-Carmona, P., Ruiz-Mateos, R., Fano, J. B., Shapeti, A., Martín‐Alfonso, J. E., Domínguez, J., Oosterwyck, H. V., Reina-Romo, E., & Sanz‐Herrera, J. A. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.07.002 · Cited by 16 · see citing works

Image-Based Method to Quantify Decellularization of Tissue Sections

Narciso, M., Otero, J., Navajas, D., Farré, R., Almendros, I., & Gavara, N. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168399 · Cited by 16 · see citing works

Monitoring matrix remodeling in the cellular microenvironment using microrheology for complex cellular systems

Hafner, J., Garces, D. G., Ludwig‐Husemann, A., Bertels, S., Bensinger, L., Raić, A., Gebauer, J. E., Oelschlaeger, C., Bastmeyer, M., Bieback, K., et al. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.04.053 · Cited by 15 · see citing works

The impact of brain cell metabolism and extracellular matrix on magnesium degradation

Unbehau, R., Luthringer-Feyerabend, B., & Willumeit‐Römer, R. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.08.043 · Cited by 15 · see citing works

Engineering stromal heterogeneity in cancer

Tang, L. J. W., Zaseela, A., Toh, C. C. M., Adine, C., Aydar, A. O., Iyer, N. G., & Fong, E. L. S. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.05.027 · Cited by 15 · see citing works

Surface stiffness depended gingival mesenchymal stem cell sensitivity to oxidative stress

Šimoliūnas, E., Ivanauskienė, I., Bagdzevičiūtė, L., Rinkūnaitė, I., Alksnė, M., & Baltriukienė, D. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.04.012 · Cited by 14 · see citing works

Tunable three-dimensional engineered prostate cancer tissues for in vitro recapitulation of heterogeneous in vivo prostate tumor stiffness

Habbit, N. L., Anbiah, B., Anderson, L., Suresh, J., Hassani, I., Eggert, M., Brannen, A. D., Davis, J. T., Tian, Y., Prabhakarpandian, B., et al. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.05.011 · Cited by 14 · see citing works

Engineering approaches to studying cancer cell migration in three-dimensional environments

Zuela-Sopilniak, N., & Lammerding, J. (2019) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2018.0219 · Cited by 14 · see citing works

The role of extracellular matrix in tumour angiogenesis: the throne has NOx servants

Alsharabasy, A. M., Glynn, S. A., & Pandit, A. S. (2020) · Biochemical Society Transactions · doi:10.1042/bst20200208 · Cited by 13 · see citing works

Texture Analysis of Tumor and Peritumoral Tissues Based on 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Hybrid Imaging in Patients With Rectal Cancer

Vé, O., Ashykhmin, A., Golovko, T., Rykhalskyi, O., & Orel, V. B. (2021) · Journal of Computer Assisted Tomography · doi:10.1097/rct.0000000000001218 · Cited by 13 · see citing works

Tuning the Cell and Biological Tissue Environment through Magneto-Active Materials

González‐Rico, J., Sardinha, E. N., Valencia, L., Árias, A., Muñoz‐Barrutia, A., Velasco, D., & Garcia‐Gonzalez, D. (2021) · Applied Sciences · doi:10.3390/app11188746 · Cited by 13 · see citing works

The dynamic tumor extracellular matrix: Biophysical cues, cellular crosstalk, and disease progression

Joshi, O., Hamidi, H., Mathieu, M., & Ivaska, J. (2026) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2026.100652 · Cited by 3 · see citing works

Engineering the Extracellular Matrix to Model the Evolving Tumor Microenvironment

Micek, H. M., Visetsouk, M. R., Masters, K. S. B., & Kreeger, P. K. (2020) · iScience · doi:10.1016/j.isci.2020.101742 · Cited by 53 · see citing works

Engineered ECM models: Opportunities to advance understanding of tumor heterogeneity

Shimpi, A. A., & Fischbach, C. (2021) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2021.04.001 · Cited by 25 · see citing works

Insights into the mechanisms, regulation, and therapeutic implications of extracellular matrix stiffness in cancer

Zhang, X., Al-Danakh, A., Zhu, X., Feng, D., Yang, L., Wu, H., Li, Y., Wang, S., Chen, Q., & Yang, D. (2024) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10698 · Cited by 36 · see citing works

The Extracellular Matrix: Its Composition, Function, Remodeling, and Role in Tumorigenesis

Dzobo, K., & Dandara, C. (2023) · Biomimetics · doi:10.3390/biomimetics8020146 · Cited by 209 · see citing works