Evidence supporting an altered immune response in ASD

Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2014

Baio, J., Wiggins, L., Christensen, D. L., Maenner, M. J., Daniels, J., Warren, Z., Kurzius-Spencer, M., Zahorodny, W., Robinson, C., Rosenberg, et al. (2018) · MMWR. Surveillance Summaries · doi:10.15585/mmwr.ss6706a1 · Cited by 6,078 · see citing works

Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2016

Maenner, M. J., Shaw, K. A., Baio, J., EdS1, Washington, A., Patrick, M., DiRienzo, M., Christensen, D. L., Wiggins, L. D., Pettygrove, S., et al. (2020) · MMWR. Surveillance Summaries · doi:10.15585/mmwr.ss6904a1 · Cited by 3,780 · see citing works

The Classical Complement Cascade Mediates CNS Synapse Elimination

Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.036 · Cited by 3,313 · see citing works

Neuroglial activation and neuroinflammation in the brain of patients with autism

Vargas, D. L., Nascimbene, C., Krishnan, C., Zimmerman, A. W., & Pardo, C. A. (2005) · Annals of Neurology · doi:10.1002/ana.20315 · Cited by 2,149 · see citing works

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

Hallmayer, J. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.76 · Cited by 1,970 · see citing works

Neuroanatomy of autism

Amaral, D. G., Schumann, C. M., & Nordahl, C. W. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2007.12.005 · Cited by 1,492 · see citing works

Prevalence of autism spectrum disorder among children aged 8 Years - Autism and developmental disabilities monitoring network, 11 Sites, United States, 2014

Naarden Braun, K. V., Lopez, M., White, T., et al. (2023) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/y3kk-5x30 · Cited by 1,381 · see citing works

Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome

Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R., Pessah, I., & Van de Water, J. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.08.003 · Cited by 940 · see citing works

Maternal Infection Requiring Hospitalization During Pregnancy and Autism Spectrum Disorders

Atladóttir, H. Ó., Thorsen, P., Østergaard, L., Schendel, D. E., Lemcke, S., Abdallah, M., & Parner, E. T. (2010) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-010-1006-y · Cited by 916 · see citing works

Cytokine-induced sickness behavior: where do we stand?

Dantzer, R. (2001) · Brain, Behavior, and Immunity · doi:10.1006/brbi.2000.0613 · Cited by 862 · see citing works

Elevated immune response in the brain of autistic patients

Li, X., Chauhan, A., Sheikh, A. M., Patil, S., Chauhan, V., Li, X.-M., Ji, L., Brown, T., & Malik, M. (2009) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.12.002 · Cited by 786 · see citing works

White matter structure in autism: preliminary evidence from diffusion tensor imaging

Barnea‐Goraly, N., Kwon, H., Menon, V., D, S. E. M., Lotspeich, L. J., & Reiss, A. L. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.10.022 · Cited by 780 · see citing works

Immune involvement in schizophrenia and autism: Etiology, pathology and animal models

Patterson, P. H. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.12.016 · Cited by 766 · see citing works

Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism

Morgan, J. T., Chana, G., Pardo, C. A., Achim, C., Semendeferi, K., Buckwalter, J., Courchesne, E., & Everall, I. P. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.05.024 · Cited by 749 · see citing works

The immune response in autism: a new frontier for autism research

Ashwood, P., Wills, S., & Van de Water, J. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.1205707 · Cited by 528 · see citing works

Microglial Activation in Young Adults With Autism Spectrum Disorder

Suzuki, K., Sugihara, G., Ouchi, Y., Nakamura, K., Futatsubashi, M., Takebayashi, K., Yoshihara, Y., Omata, K., Matsumoto, K., Tsuchiya, K. J., et al. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.272 · Cited by 523 · see citing works

AUTISM IN THALIDOMIDE EMBRYOPATHY: A POPULATION STUDY

Strömland, K., Nordin, V., Miller, M. T., Åkerström, B., & Gillberg, C. (1994) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1994.tb11856.x · Cited by 453 · see citing works

Association of Family History of Autoimmune Diseases and Autism Spectrum Disorders

Atladóttir, H. O., Pedersen, M. G., Thorsen, P., Mortensen, P. B., Deleuran, B., Eaton, W. W., & Parner, E. T. (2009) · Pediatrics · doi:10.1542/peds.2008-2445 · Cited by 404 · see citing works

A genetic variant that disrupts <i>MET</i> transcription is associated with autism

Campbell, D. B., Sutcliffe, J. S., Ebert, P. J., Militerni, R., Bravaccio, C., Trillo, S., Elia, M., Schneider, C., Melmed, R., Sacco, R., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605296103 · Cited by 401 · see citing works

MHC Class I: An Unexpected Role in Neuronal Plasticity

Shatz, C. J. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.044 · Cited by 369 · see citing works

Maternal Autoimmune Diseases, Asthma and Allergies, and Childhood Autism Spectrum Disorders

Croen, L., Grether, J. K., Yoshida, C. K., Odouli, R., & de Water, J. V. (2005) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.159.2.151 · Cited by 360 · see citing works

Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study

Goines, P. E., Croen, L. A., Braunschweig, D., Yoshida, C. K., Grether, J., Hansen, R., Kharrazi, M., Ashwood, P., & Van de Water, J. (2011) · Molecular Autism · doi:10.1186/2040-2392-2-13 · Cited by 351 · see citing works

IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation

Wei, H., Zou, H., Sheikh, A. M., Malik, M., Dobkin, C., Brown, W. T., & Li, X. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-52 · Cited by 333 · see citing works

Activation of the Inflammatory Response System in Autism

Croonenberghs, J., Bosmans, E., Deboutte, D., Kenis, G., & Maes, M. H. J. (2002) · Neuropsychobiology · doi:10.1159/000048665 · Cited by 323 · see citing works

Regulation of CNS synapses by neuronal MHC class I

Goddard, C. A., Butts, D. A., & Shatz, C. J. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702023104 · Cited by 322 · see citing works

IFN-γ-dependent activation of the brain’s choroid plexus for CNS immune surveillance and repair

Kunis, G., Baruch, K., Rosenzweig, N., Kertser, A., Miller, O., Berkutzki, T., & Schwartz, M. (2013) · Brain · doi:10.1093/brain/awt259 · Cited by 321 · see citing works

Cytokine dysregulation in autism spectrum disorders (ASD): Possible role of the environment

Goines, P. E., & Ashwood, P. (2013) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2012.07.006 · Cited by 314 · see citing works

Pro- and anti-inflammatory cytokines expression in rat's brain and spleen exposed to chronic mild stress: Involvement in depression

You, Z., Luo, C., Zhang, W., Chen, Y., He, J., Zhao, Q., Zuo, R. M., & Wu, Y. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.07.006 · Cited by 301 · see citing works

Differential monocyte responses to TLR ligands in children with autism spectrum disorders

Enstrom, A. M., Onore, C. E., Van de Water, J. A., & Ashwood, P. (2010) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2009.08.001 · Cited by 294 · see citing works

Autism: maternally derived antibodies specific for fetal brain proteins.

Braunschweig, D., Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R. L., Croen, L., Pessah, I., & van de Water, J. A. (2007) · Neurotoxicology · doi:10.1016/j.neuro.2007.10.010 · Cited by 281 · see citing works

Altered T cell responses in children with autism

Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R., Pessah, I. N., & Van de Water, J. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.09.002 · Cited by 281 · see citing works

Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders

Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R., Pessah, I. N., & Van de Water, J. (2011) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.10.025 · Cited by 279 · see citing works

Is Maternal Influenza or Fever During Pregnancy Associated with Autism or Developmental Delays? Results from the CHARGE (CHildhood Autism Risks from Genetics and Environment) Study

Zerbo, O., Iosif, A.-M., Walker, C., Ozonoff, S., Hansen, R. L., & Hertz-Picciotto, I. (2013) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-012-1540-x · Cited by 277 · see citing works

Decreased transforming growth factor beta1 in autism: A potential link between immune dysregulation and impairment in clinical behavioral outcomes

Ashwood, P., Enstrom, A., Krakowiak, P., Hertz-Picciotto, I., Hansen, R. L., Croen, L. A., Ozonoff, S., Pessah, I. N., & de Water, J. V. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.07.006 · Cited by 271 · see citing works

Autism and gastrointestinal symptoms

Horvath, K., & Perman, J. A. (2002) · Current Gastroenterology Reports · doi:10.1007/s11894-002-0071-6 · Cited by 260 · see citing works

Altered gene expression and function of peripheral blood natural killer cells in children with autism

Enstrom, A. M., Lit, L., Onore, C. E., Gregg, J. P., Hansen, R. L., Pessah, I. N., Hertz-Picciotto, I., Van de Water, J. A., Sharp, F. R., & Ashwood, P. (2009) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2008.08.001 · Cited by 257 · see citing works

Autism-specific maternal autoantibodies recognize critical proteins in developing brain

Braunschweig, D., Krakowiak, P., Duncanson, P., Boyce, R., Hansen, R. L., Ashwood, P., Hertz-Picciotto, I., Pessah, I. N., & Van de Water, J. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.50 · Cited by 257 · see citing works

How Do Immune Cells Support and Shape the Brain in Health, Disease, and Aging?

Schwartz, M., Kipnis, J., Rivest, S., & Prat, A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3241-13.2013 · Cited by 256 · see citing works

Th1- and Th2-like cytokines in CD4+ and CD8+ T cells in autism

Gupta, S., Aggarwal, S., Rashanravan, B., & Lee, T. (1998) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(98)00021-6 · Cited by 250 · see citing works

Prevalence of chronic gastrointestinal symptoms in children with autism and autistic spectrum disorders

Molloy, C. A., & Manning-Courtney, P. (2003) · Autism · doi:10.1177/1362361303007002004 · Cited by 249 · see citing works

Gastrointestinal symptoms in a sample of children with pervasive developmental disorders

Nikolov, R. N., Bearss, K. E., Lettinga, J., Erickson, C., Rodowski, M., Aman, M. G., McCracken, J. T., McDougle, C. J., Tierney, E., Vitiello, B., et al. (2009) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-008-0637-8 · Cited by 240 · see citing works

Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from mothers of children with autism

Martin, L. A., Ashwood, P., Braunschweig, D., Cabanlit, M., Van de Water, J., & Amaral, D. G. (2008) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.12.007 · Cited by 231 · see citing works

Adaptive immunity affects learning behavior in mice

Brynskikh, A., Warren, T., Zhu, J., & Kipnis, J. (2008) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.12.008 · Cited by 221 · see citing works

Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases

Tian, L., Ma, L., Kaarela, T., & Li, Z. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-155 · Cited by 218 · see citing works

A dual role for interleukin-1 in LTP in mouse hippocampal slices

Ross, F. M., Allan, S. M., Rothwell, N. J., & Verkhratsky, A. (2003) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2003.08.030 · Cited by 214 · see citing works

Spontaneous Mucosal Lymphocyte Cytokine Profiles in Children with Autism and Gastrointestinal Symptoms: Mucosal Immune Activation and Reduced Counter Regulatory Interleukin-10

ASHWOOD, P., ANTHONY, A., TORRENTE, F., & WAKEFIELD, A. J. (2004) · Journal of Clinical Immunology · doi:10.1007/s10875-004-6241-6 · Cited by 212 · see citing works

Immunological and autoimmune considerations of Autism Spectrum Disorders

Gesundheit, B., Rosenzweig, J. P., Naor, D., Lerer, B., Zachor, D. A., Procházka, V., Melamed, M., Kristt, D. A., Steinberg, A., Shulman, C., et al. (2013) · Journal of Autoimmunity · doi:10.1016/j.jaut.2013.05.005 · Cited by 207 · see citing works

Depressed lymphocyte responsiveness in autistic children

Stubbs, E. G., Crawford, M. L., Burger, D. R., & Vandenbark, A. A. (1977) · Journal of Autism and Childhood Schizophrenia · doi:10.1007/bf01531114 · Cited by 202 · see citing works

Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms

Ashwood, P., & Wakefield, A. J. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2005.12.007 · Cited by 202 · see citing works

Plasma increase of interleukin-12 and interferon-gamma. Pathological significance in autism

Singh, V. K. (1996) · Journal of Neuroimmunology · doi:10.1016/0165-5728(96)00014-8 · Cited by 199 · see citing works

Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development

Gadient, R. A., & Otten, U. (1994) · Brain Research · doi:10.1016/0006-8993(94)91211-4 · Cited by 195 · see citing works

Elevated serum levels of interleukin-17A in children with autism

AL-Ayadhi, L. Y., & Mostafa, G. A. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-158 · Cited by 193 · see citing works

Reduced Natural Killer Cell Activity in Autism

WARREN, R. P., FOSTER, A., & MARGARETTEN, N. C. (1987) · Journal of the American Academy of Child &amp; Adolescent Psychiatry · doi:10.1097/00004583-198705000-00008 · Cited by 190 · see citing works

Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms

Heuer, L., Ashwood, P., Schauer, J., Goines, P., Krakowiak, P., Hertz‐Picciotto, I., Hansen, R., Croen, L. A., Pessah, I. N., & Van de Water, J. (2008) · Autism Research · doi:10.1002/aur.42 · Cited by 190 · see citing works

Targeted CNS Expression of Interferon-γ in Transgenic Mice Leads to Hypomyelination, Reactive Gliosis, and Abnormal Cerebellar Development

Corbin, J. G., Kelly, D., Rath, E. M., Baerwald, K. D., Suzuki, K., & Popko, B. (1996) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1996.0026 · Cited by 184 · see citing works

Gene expression changes in children with autism

Gregg, J. P., Lit, L., Baron, C. A., Hertz-Picciotto, I., Walker, W., Davis, R. A., Croen, L. A., Ozonoff, S., Hansen, R., Pessah, I. N., et al. (2008) · Genomics · doi:10.1016/j.ygeno.2007.09.003 · Cited by 181 · see citing works

Recent progress in animal modeling of immune inflammatory processes in schizophrenia: Implication of specific cytokines

Nawa, H., & Takei, N. (2006) · Neuroscience Research · doi:10.1016/j.neures.2006.06.002 · Cited by 174 · see citing works

Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey

Bauman, M. D., Iosif, A.-M., Ashwood, P., Braunschweig, D., Lee, A., Schumann, C. M., Van de Water, J., & Amaral, D. G. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.47 · Cited by 174 · see citing works

Maternal Mid-Pregnancy Autoantibodies to Fetal Brain Protein: The Early Markers for Autism Study

Croen, L., Braunschweig, D., Haapanen, L. A. D., Yoshida, C. K., FIREMAN, B. H., Grether, J. K., Kharrazi, M., Hansen, R. L., Ashwood, P., & de Water, J. V. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.05.006 · Cited by 171 · see citing works

Altered Cytokine and BDNF Levels in Autism Spectrum Disorder

Ricci, S., Businaro, R., Ippoliti, F., Vasco, V. R. L., Massoni, F., Onofri, E., Troili, G. M., Pontecorvi, V., Morelli, M., Ricciardi, M. R., et al. (2013) · Neurotoxicity Research · doi:10.1007/s12640-013-9393-4 · Cited by 165 · see citing works

Cytokine regulation of embryonic rat dopamine and serotonin neuronal survival in vitro

Jarskog, L. F., Xiao, H., Wilkie, M. B., Lauder, J. M., & Gilmore, J. H. (1997) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(97)00029-4 · Cited by 163 · see citing works

High blood monocyte counts and neopterin levels in children with autistic disorder.

Sweeten, T. L., Posey, D., & McDougle, C. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.9.1691 · Cited by 157 · see citing works

Brain‐Specific Autoantibodies in the Plasma of Subjects with Autistic Spectrum Disorder

CABANLIT, M., WILLS, S., GOINES, P., ASHWOOD, P., & VAN DE WATER, J. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1381.010 · Cited by 157 · see citing works

Antibodies against fetal brain in sera of mothers with autistic children

Singer, H. S., Morris, C. M., Gause, C. D., Gillin, P. K., Crawford, S., & Zimmerman, A. W. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2007.11.004 · Cited by 152 · see citing works

The neurobiological basis of autism from a developmental perspective

Akshoomoff, N. A., Pierce, K., & Courchesne, E. (2002) · Development and Psychopathology · doi:10.1017/s0954579402003115 · Cited by 145 · see citing works

Celecoxib as adjunctive treatment to risperidone in children with autistic disorder: a randomized, double-blind, placebo-controlled trial

Asadabadi, M., Mohammadi, M.-R., Ghanizadeh, A. J., Modabbernia, A., Ashrafi, M., Hassanzadeh, E., Forghani, S., & Akhondzadeh, S. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2796-8 · Cited by 143 · see citing works

In Search of Cellular Immunophenotypes in the Blood of Children with Autism

Ashwood, P., Corbett, B. A., Kantor, A. B., Schulman, H., de Water, J. V., & Amaral, D. G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019299 · Cited by 141 · see citing works

Microglia and Macrophages in the Developing CNS

Streit, W. J. (2001) · NeuroToxicology · doi:10.1016/s0161-813x(01)00033-x · Cited by 134 · see citing works

Decreased serum levels of transforming growth factor-β1 in patients with autism

Okada, K., Hashimoto, K., Iwata, Y., Nakamura, K., Tsujii, M., Tsuchiya, K. J., Sekine, Y., Suda, S., Suzuki, K., Sugihara, G.-I., et al. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.08.020 · Cited by 132 · see citing works

Strong association of the third hypervariable region of HLA-DRβ1 with autism

Warren, R. P., Odell, J. D., Warren, W. L., Burger, R. A., Maciulis, A., Daniels, W. W., & Torres, A. R. (1996) · Journal of Neuroimmunology · doi:10.1016/0165-5728(96)00052-5 · Cited by 130 · see citing works

Increased serum albumin, γ globulin, immunoglobulin IgG, and IgG2 and IgG4 in autism

Croonenberghs, J., Wauters, A., Devreese, K. M. J., Verkerk, R. M., Scharpé, S., Bosmans, E., Egyed, B., Deboutte, D., & Maes, M. H. J. (2002) · Psychological Medicine · doi:10.1017/s0033291702006037 · Cited by 128 · see citing works

Maternal Autoantibodies in Autism

Braunschweig, D., & Van de Water, J. (2012) · Archives of Neurology · doi:10.1001/archneurol.2011.2506 · Cited by 122 · see citing works

Effect of systemic LPS injection on cortical NF-κB activity and inflammatory response following traumatic brain injury in rats

Hang, C., Shi, J., Tian, J., Li, J., Wu, W., & Yin, H.-X. (2004) · Brain Research · doi:10.1016/j.brainres.2004.07.090 · Cited by 121 · see citing works

Common neurological co-morbidities in autism spectrum disorders

Maski, K. P., Jeste, S., & Spence, S. J. (2011) · Current Opinion in Pediatrics · doi:10.1097/mop.0b013e32834c9282 · Cited by 112 · see citing works

H2-K b and H2-D b regulate cerebellar long-term depression and limit motor learning

McConnell, M. J., Huang, Y. H., Datwani, A., & Shatz, C. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902018106 · Cited by 112 · see citing works

Autoimmunity in autism.

Enstrom, A. M., de Water, J. V., & Ashwood, P. (2009) · PubMed · Cited by 107 · see citing works

Cutting Edge: Peripheral Neuropeptides Attract Immature and Arrest Mature Blood-Derived Dendritic Cells

Dunzendorfer, S., Kaser, A., Meierhofer, C., Tilg, H., & Wiedermann, C. J. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.4.2167 · Cited by 106 · see citing works

HLA-DR4 in Families With Autism

Lee, L.-C., Zachary, A. A., Leffell, M. S., Newschaffer, C. J., Matteson, K. J., Tyler, J. D., & Zimmerman, A. W. (2006) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2006.06.006 · Cited by 106 · see citing works

Lymphocyte subsets and interleukin-2 receptors in autistic children

Denney, D. R., Frei, B. W., & Gaffney, G. (1996) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02276236 · Cited by 105 · see citing works

C1q: the perfect complement for a synaptic feast?

Perry, V. H., & O'Connor, V. M. (2008) · Nature reviews. Neuroscience · doi:10.1038/nrn2394 · Cited by 101 · see citing works

Increased IgG4 levels in children with autism disorder

Enstrom, A., Krakowiak, P., Onore, C., Pessah, I. N., Hertz-Picciotto, I., Hansen, R. L., Van de Water, J. A., & Ashwood, P. (2009) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2008.12.005 · Cited by 101 · see citing works

An Autistic Endophenotype Results in Complex Immune Dysfunction in Healthy Siblings of Autistic Children

Saresella, M., Marventano, I., Guerini, F. R., Mancuso, R., Ceresa, L., Zanzottera, M., Rusconi, B., Maggioni, E., Tinelli, C., & Clerici, M. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.06.020 · Cited by 98 · see citing works

Brief Report: Plasma Leptin Levels are Elevated in Autism: Association with Early Onset Phenotype?

Ashwood, P., Kwong, C., Hansen, R. L., Hertz‐Picciotto, I., Croen, L., Krakowiak, P., Walker, W. L., Pessah, I. N., & de Water, J. V. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0353-1 · Cited by 97 · see citing works

Maternal autoantibodies are associated with abnormal brain enlargement in a subgroup of children with autism spectrum disorder

Nordahl, C. W., Braunschweig, D., Iosif, A.-M., Lee, A., Rogers, S., Ashwood, P., Amaral, D. G., & Van de Water, J. (2013) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2013.01.084 · Cited by 95 · see citing works

Drug therapy in autism: a present and future perspective

Kumar, B., Prakash, A., Sewal, R. K., Medhi, B., & Modi, M. (2012) · Pharmacological Reports · doi:10.1016/s1734-1140(12)70927-1 · Cited by 85 · see citing works

The association between epilepsy and autism symptoms and maladaptive behaviors in children with autism spectrum disorder

Viscidi, E. W., Johnson, A. L., Spence, S. J., Buka, S. L., Morrow, E. M., & Triche, E. W. (2014) · Autism · doi:10.1177/1362361313508027 · Cited by 82 · see citing works

Myeloid dendritic cells frequencies are increased in children with autism spectrum disorder and associated with amygdala volume and repetitive behaviors

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Repetitive Restricted Behaviors in Autism Spectrum Disorder: From Mechanism to Development of Therapeutics

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Inflammatory Biomarkers are Correlated with Some Forms of Regressive Autism Spectrum Disorder

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Microglia and Brain Disorders: The Role of Vitamin D and Its Receptor

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B and T Immunoregulation: A New Insight of B Regulatory Lymphocytes in Autism Spectrum Disorder

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Feeding Disorders in Children With Autism Spectrum Disorders Are Associated With Eosinophilic Esophagitis

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The Putative Role of Environmental Mercury in the Pathogenesis and Pathophysiology of Autism Spectrum Disorders and Subtypes

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Endosulfan and Cypermethrin Pesticide Mixture Induces Synergistic or Antagonistic Effects on Developmental Exposed Rats Depending on the Analyzed Behavioral or Neurochemical End Points

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Neuroinflammation in Autism Spectrum Disorders: Role of High Mobility Group Box 1 Protein.

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Immunological Biomarkers in Autism Spectrum Disorder: The Role of TNF-Alpha and Dependent Trends in Serum IL-6 and CXCL8

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Maternal treatment with sodium butyrate reduces the development of autism-like traits in mice offspring

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A Unifying Theory for Autism: The Pathogenetic Triad as a Theoretical Framework

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Maternal Immune Dysregulation and Autism–Understanding the Role of Cytokines, Chemokines and Autoantibodies

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