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Hemogenic Endothelial Fate Mapping Reveals Dual Developmental Origin of Mast Cells
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In the citing paper
“In contrast, mast cells loaded with heparin‐containing granules have been reported only at E14.5‐E15.5 in the murine and rat skin. 49 , 53 , 56”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
In the citing paper
“However, BM contribution is equally limited in “shielded” chimeras, in which most of the body is protected from irradiation, 53 as well as in parabiotic animals that are not irradiated at all. 24”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
In the citing paper
“Indeed, integrin α4β7 is expressed by EMP‐derived progenitors that can be found in the fetal liver at E11.5. 53 , 54”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
In the citing paper
“Three different fate mapping approaches unequivocally established that in vivo and under physiological conditions, the first mast cells are produced from YS EMPs. 53 , 54”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
In the citing paper
“which is also expressed by fetal mast cells and their progenitors. 53 , 63”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
In the citing paper
“The frequency of EMP‐derived mast cells gradually declines over time, although sizeable populations are retained in adult connective tissues, such as the body skin, as well as adipose tissues.”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
In the citing paper
“The first mast cell progenitors arise from the erythro‐myeloid progenitors (EMPs) produced in the extra‐embryonic yolk sac starting at embryonic day 8.25 (E8.25).”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
In the citing paper
“At least on transcript level, fetal mast cells also express key effectors like proteases. 53 , 54 , 63 This is also true for human fetal mast cells, which express, for example, TPSAB1, the gene encoding tryptase, and carry granules. 59 , 60 , 63”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
In the citing paper
“While surface expression of FcεR1 is only upregulated perinatally, 53 , 63 fetal mast cells express other receptors through which they can sense the environment, such as the IL‐33 receptor. 53 , 54 , 63 They can also respond to environmental signals and stressors already in utero. 63”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
In the citing paper
“Indeed, mast cells appear to be functionally mature at fetal stages: In mice, mast cells detected as early as E12.5 in the cornea and E14.5 in the skin already contain characteristic granules. 53 , 55”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
In the citing paper
“Considering that turnover from the BM is very low for mast cells in connective tissues populations, 23 , 53 such HSC‐derived mast cell progenitors might be recruited in the perinatal window prior to settling in the BM.”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [53]
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Citations
Cites
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
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Self-citationTissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
Gomez Perdiguero, E., Klapproth, K., Schulz, C., Busch, K., Azzoni, E., Crozet, L., Garner, H., Trouillet, C., de Bruijn, M. F., Geissmann, F., et al. (2015) · Nature · doi:10.1038/nature13989 · Cited by 2,339
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Self-citationSpecification of tissue-resident macrophages during organogenesis
Mass, E., Ballesteros, I., Farlik, M., Halbritter, F., Günther, P., Crozet, L., Jacome-Galarza, C. E., Händler, K., Klughammer, J., Kobayashi, Y., et al. (2016) · Science · doi:10.1126/science.aaf4238 · Cited by 891
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Metadata
- Authors
- Gentek, R., Ghigo, C., Hoeffel, G., Bulle, M. J., Msallam, R., Gautier, G., Launay, P., Chen, J., Ginhoux, F., & Bajénoff, M.
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2018-06
- Volume
- 48
- Issue
- 6
- Pages
- 1160-1171.e5
- ISSN
- 1074-7613
- Cited by
- 336
- References
- 7
- Language
- en
- Licence
- Funders
- Agence National pour la Recherche (ANR-10-INBS-04-01, ANR-10-INBS-0009)
- European Research Council (647257-STROMA)
- INSERM
- CNRS
- Aix-Marseille University
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- Gentek, R., Ghigo, C., Hoeffel, G., Bulle, M. J., Msallam, R., Gautier, G., Launay, P., Chen, J., Ginhoux, F., & Bajénoff, M. (2018). Hemogenic Endothelial Fate Mapping Reveals Dual Developmental Origin of Mast Cells. Immunity. https://doi.org/10.1016/j.immuni.2018.04.025
