CoChat
Sign Up
Cited by 475

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

microRNAs and the immune response

Lindsay, Mark A.·2008·Trends in Immunology
DOI 10.1016/j.it.2008.04.004
Open this paper in CoChat — free account

Abstract

microRNA (miRNA)-mediated RNA interference has been identified as a novel mechanism that regulates protein expression at the translational level. Recent publications have provided compelling evidence that a range of miRNAs are involved in the regulation of immunity, including the development and differentiation of B and T cells, proliferation of monocytes and neutrophils, antibody switching and the release of inflammatory mediators. In this review, we examine what is presently known of the function and mechanism of action of these miRNAs in the regulation of the innate and acquired immune response.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.it.2008.04.004

Cites

9 of 9 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 74

  1. Fire, 1998, Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans, Nature, 391, 806, 10.1038/35888 · DOI · Paper page
  2. Williams, 2008, Functional aspects of animal microRNAs, Cell. Mol. Life Sci., 65, 545, 10.1007/s00018-007-7355-9 · DOI
  3. Stefani, 2008, Small non-coding RNAs in animal development, Nat. Rev. Mol. Cell Biol., 9, 219, 10.1038/nrm2347 · DOI
  4. Chen, 2004, MicroRNAs modulate hematopoietic lineage differentiation, Science, 303, 83, 10.1126/science.1091903 · DOI · Paper page
  5. Cobb, 2005, T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer, J. Exp. Med., 201, 1367, 10.1084/jem.20050572 · DOI
  6. Cobb, 2006, A role for Dicer in immune regulation, J. Exp. Med., 203, 2519, 10.1084/jem.20061692 · DOI
  7. Muljo, 2005, Aberrant T cell differentiation in the absence of Dicer, J. Exp. Med., 202, 261, 10.1084/jem.20050678 · DOI
  8. Li, 2007, miR-181a is an intrinsic modulator of T cell sensitivity and selection, Cell, 129, 147, 10.1016/j.cell.2007.03.008 · DOI
  9. Fazi, 2005, A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis, Cell, 123, 819, 10.1016/j.cell.2005.09.023 · DOI · Paper page
  10. Moschos, 2007, Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids, BMC Genomics, 8, 240, 10.1186/1471-2164-8-240 · DOI
  11. Johnnidis, 2008, Regulation of progenitor cell proliferation and granulocyte function by microRNA-223, Nature, 451, 1125, 10.1038/nature06607 · DOI · Paper page
  12. Fontana, 2007, MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation, Nat. Cell Biol., 9, 775, 10.1038/ncb1613 · DOI · Paper page
  13. O’Connell, 2007, MicroRNA-155 is induced during the macrophage inflammatory response, Proc. Natl. Acad. Sci. U. S. A., 104, 1604, 10.1073/pnas.0610731104 · DOI · Paper page
  14. Tili, 2007, Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-{alpha} Stimulation and Their Possible Roles in Regulating the Response to Endotoxin Shock, J. Immunol., 179, 5082, 10.4049/jimmunol.179.8.5082 · DOI · Paper page
  15. Perry, 2008, Rapid changes in microRNA-146a expression negatively regulate the interleukin-1β induced inflammatory response in human lung alveolar epithelial cells, J. Immunol., 180, 5689, 10.4049/jimmunol.180.8.5689 · DOI · Paper page
  16. Cullen, 2006, Viruses and microRNAs, Nat. Genet., 38, S25, 10.1038/ng1793 · DOI
  17. Sarnow, 2006, MicroRNAs: expression, avoidance and subversion by vertebrate viruses, Nat. Rev. Microbiol., 4, 651, 10.1038/nrmicro1473 · DOI
  18. Jopling, 2005, Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA, Science, 309, 1577, 10.1126/science.1113329 · DOI
  19. Pedersen, 2007, Interferon modulation of cellular microRNAs as an antiviral mechanism, Nature, 449, 919, 10.1038/nature06205 · DOI
  20. Lecellier, 2005, A cellular microRNA mediates antiviral defense in human cells, Science, 308, 557, 10.1126/science.1108784 · DOI
  21. Otsuka, 2007, Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression, Immunity, 27, 123, 10.1016/j.immuni.2007.05.014 · DOI
  22. Taganov, 2007, MicroRNAs and immunity: tiny players in a big field, Immunity, 26, 133, 10.1016/j.immuni.2007.02.005 · DOI
  23. Lodish, 2008, Micromanagement of the immune system by microRNAs, Nat. Rev. Immunol., 8, 120, 10.1038/nri2252 · DOI
  24. Calin, 2006, MicroRNA signatures in human cancers, Nat. Rev. Cancer, 6, 857, 10.1038/nrc1997 · DOI
  25. Croce, 2005, miRNAs, cancer, and stem cell division, Cell, 122, 6, 10.1016/j.cell.2005.06.036 · DOI
  26. Doench, 2003, siRNAs can function as miRNAs, Genes Dev., 17, 438, 10.1101/gad.1064703 · DOI
  27. Saetrom, 2007, Distance constraints between microRNA target sites dictate efficacy and cooperativity, Nucleic Acids Res., 35, 2333, 10.1093/nar/gkm133 · DOI
  28. Long, 2007, Potent effect of target structure on microRNA function, Nat. Struct. Mol. Biol., 14, 287, 10.1038/nsmb1226 · DOI
  29. Linsley, 2007, Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression, Mol. Cell. Biol., 27, 2240, 10.1128/MCB.02005-06 · DOI · Paper page
  30. Jing, 2005, Involvement of microRNA in AU-rich element-mediated mRNA instability, Cell, 120, 623, 10.1016/j.cell.2004.12.038 · DOI
  31. Ota, 2004, Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma, Cancer Res., 64, 3087, 10.1158/0008-5472.CAN-03-3773 · DOI
  32. He, 2005, A microRNA polycistron as a potential human oncogene, Nature, 435, 828, 10.1038/nature03552 · DOI
  33. Ventura, 2008, Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters, Cell, 132, 875, 10.1016/j.cell.2008.02.019 · DOI
  34. Koralov, 2008, Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage, Cell, 132, 860, 10.1016/j.cell.2008.02.020 · DOI
  35. Xiao, 2008, Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes, Nat. Immunol., 9, 405, 10.1038/ni1575 · DOI
  36. Kluiver, 2005, BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas, J. Pathol., 207, 243, 10.1002/path.1825 · DOI
  37. Eis, 2005, Accumulation of miR-155 and BIC RNA in human B cell lymphomas, Proc. Natl. Acad. Sci. U. S. A., 102, 3627, 10.1073/pnas.0500613102 · DOI
  38. Metzler, 2004, High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma, Genes Chromosomes Cancer, 39, 167, 10.1002/gcc.10316 · DOI
  39. Costinean, 2006, Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E{micro}-miR155 transgenic mice, Proc. Natl. Acad. Sci. U. S. A., 103, 7024, 10.1073/pnas.0602266103 · DOI
  40. Fulci, 2007, Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia, Blood, 109, 4944, 10.1182/blood-2006-12-062398 · DOI
  41. Thai, 2007, Regulation of the germinal center response by microRNA-155, Science, 316, 604, 10.1126/science.1141229 · DOI
  42. Vigorito, 2007, microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells, Immunity, 27, 847, 10.1016/j.immuni.2007.10.009 · DOI
  43. O’Connell, 2008, Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder, J. Exp. Med., 205, 585, 10.1084/jem.20072108 · DOI · Paper page
  44. Yin, 2008, B-cell receptor activation induces BIC/miR-155 expression through a conserved AP-1 element, J. Biol. Chem., 283, 2654, 10.1074/jbc.M708218200 · DOI
  45. Neilson, 2007, Dynamic regulation of miRNA expression in ordered stages of cellular development, Genes Dev., 21, 578, 10.1101/gad.1522907 · DOI
  46. Fukao, 2007, An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling, Cell, 129, 617, 10.1016/j.cell.2007.02.048 · DOI · Paper page
  47. Chen, 2005, MicroRNAs as regulators of mammalian hematopoiesis, Semin. Immunol., 17, 155, 10.1016/j.smim.2005.01.001 · DOI
  48. Naguibneva, 2006, The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation, Nat. Cell Biol., 8, 278, 10.1038/ncb1373 · DOI
  49. Zhao, 2005, Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis, Nature, 436, 214, 10.1038/nature03817 · DOI
  50. Care, 2007, MicroRNA-133 controls cardiac hypertrophy, Nat. Med., 13, 613, 10.1038/nm1582 · DOI
  51. Rao, 2006, Myogenic factors that regulate expression of muscle-specific microRNAs, Proc. Natl. Acad. Sci. U. S. A., 103, 8721, 10.1073/pnas.0602831103 · DOI
  52. Barreau, 2006, AU-rich elements and associated factors: are there unifying principles?, Nucleic Acids Res., 33, 7138, 10.1093/nar/gki1012 · DOI · Paper page
  53. Asirvatham, 2008, MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components, Mol. Immunol., 45, 1995, 10.1016/j.molimm.2007.10.035 · DOI
  54. Lee, 2003, The nuclear RNase III Drosha initiates microRNA processing, Nature, 425, 415, 10.1038/nature01957 · DOI
  55. Zhang, 2004, Single processing center models for human Dicer and bacterial RNase III, Cell, 118, 57, 10.1016/j.cell.2004.06.017 · DOI
  56. Yi, 2003, Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs, Genes Dev., 17, 3011, 10.1101/gad.1158803 · DOI
  57. Liu, 2004, Argonaute2 is the catalytic engine of mammalian RNAi, Science, 305, 1437, 10.1126/science.1102513 · DOI · Paper page
  58. Meister, 2004, Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs, Mol. Cell, 15, 185, 10.1016/j.molcel.2004.07.007 · DOI · Paper page
  59. Lewis, 2003, Prediction of mammalian microRNA targets, Cell, 115, 787, 10.1016/S0092-8674(03)01018-3 · DOI · Paper page
  60. Doench, 2004, Specificity of microRNA target selection in translational repression, Genes Dev., 18, 504, 10.1101/gad.1184404 · DOI
  61. Didiano, 2006, Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions, Nat. Struct. Mol. Biol., 13, 849, 10.1038/nsmb1138 · DOI · Paper page
  62. Lewis, 2005, Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets, Cell, 120, 15, 10.1016/j.cell.2004.12.035 · DOI · Paper page
  63. Meister, 2004, Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing, RNA, 10, 544, 10.1261/rna.5235104 · DOI
  64. Esau, 2006, miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting, Cell Metab., 3, 87, 10.1016/j.cmet.2006.01.005 · DOI · Paper page
  65. Zeng, 2002, Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells, Mol. Cell, 9, 1327, 10.1016/S1097-2765(02)00541-5 · DOI
  66. de Fougerolles, 2007, Interfering with disease: a progress report on siRNA-based therapeutics, Nat. Rev. Drug Discov., 6, 443, 10.1038/nrd2310 · DOI
  67. John, 2007, Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway, Nature, 449, 745, 10.1038/nature06179 · DOI
  68. Soutschek, 2004, Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs, Nature, 432, 173, 10.1038/nature03121 · DOI
  69. Calin, 2002, Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia, Proc. Natl. Acad. Sci. U. S. A., 99, 15524, 10.1073/pnas.242606799 · DOI · Paper page
  70. Cimmino, 2005, miR-15 and miR-16 induce apoptosis by targeting BCL2, Proc. Natl. Acad. Sci. U. S. A., 102, 13944, 10.1073/pnas.0506654102 · DOI
  71. Raveche, 2007, Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice, Blood, 109, 5079, 10.1182/blood-2007-02-071225 · DOI
  72. Lawrie, 2007, MicroRNA expression distinguishes between germinal center B cell-like and activated B cell-like subtypes of diffuse large B cell lymphoma, Int. J. Cancer, 121, 1156, 10.1002/ijc.22800 · DOI
  73. Pekarsky, 2006, Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181, Cancer Res., 66, 11590, 10.1158/0008-5472.CAN-06-3613 · DOI
  74. Zhou, 2007, miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely, Proc. Natl. Acad. Sci. U. S. A., 104, 7080, 10.1073/pnas.0702409104 · DOI

Cited by

Sorted by citations

Metadata

Authors
Lindsay, M. A.
Venue
Trends in Immunology
Publisher
Elsevier BV
Published
2008-07
Volume
29
Issue
7
Pages
343-351
ISSN
1471-4906
DOI
10.1016/j.it.2008.04.004
Cited by
475
References
9
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review