Anxiety among adults with a history of childhood adversity: Psychological resilience moderates the indirect effect of emotion dysregulation
Abstract
Background Adverse childhood experiences (ACEs) have been widely identified as risk factors for increased symptoms of anxiety across the lifespan. Little is known, however, about the processes by which ACEs set the stage for increased symptoms of anxiety in adulthood. The current study evaluated whether emotion dysregulation and psychological resilience influence the association between ACEs and symptoms of anxiety. Methods A sample of adult primary care patients (N=4006) completed self-report measures related to ACEs, symptoms of anxiety, emotion dysregulation, and psychological resilience. Results A moderated mediation analysis showed that emotion dysregulation mediated the association between ACEs and anxiety symptoms, and that the strength of this effect varied as a function of psychological resilience. Specifically, the influence of ACEs on emotional dysregulation was stronger among individuals with low levels of psychological resilience than among those with high levels of psychological resilience. These findings remained significant when controlling for a range of sociodemographic variables in the model. Limitations Cross-sectional designs preclude inferences about causality and self-report data may be susceptible to reporting biases. Other psychological variables that may be relevant to the current results, such as protective factors in childhood, were not assessed. Conclusions These results have implications for the conceptualization of ACEs, emotion dysregulation, a…
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Robust cross-sectional and longitudinal evidence indicates a heightened risk of developing psychiatric problems after exposure to adverse childhood experiences.
“Robust cross-sectional and longitudinal evidence indicates a heightened risk of developing psychiatric problems after exposure to ACEs, including depression (Chapman et al., 2004), anxiety disorders (Poole et al., 2017), suicidal ideation (Stansfeld et al., 2017), and psychosis (Karcher et al., 2020).”
From Prospective Longitudinal Associations Between Adverse Childhood Experiences and Adult Mental Health Outcomes: Systematic Review and Meta-Analysis (2026) · cites this paper as Poole et al., 2017
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DRD4 interacts with adverse life events in predicting maternal sensitivity via emotion regulation.
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Effects Of Early Trauma and Recent Stressors on Depression, Anxiety, and Anger
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“…cross-sectional and longitudinal evidence indicates a heightened risk of developing psychiatric problems after exposure to ACEs, including depression (Chapman et al., 2004), anxiety disorders (Poole et al., 2017), suicidal ideation (Stansfeld et al., 2017), and psychosis (Karcher et al., 2020).”
Investigating state and trait aspects of resilience using Generalizability theory
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“Resilience is posited to function as a protective ‘buffer’ against the impact of adverse childhood experiences that can lead to adult depression (Poole et al., 2017a, b).”
Sports atmosphere and psychological resilience in college students: mediating role of growth mindset
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Protective Factors for Adverse Childhood Experiences: The Role of Emotion Regulation and Attachment
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Problem gambling during Covid-19
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Preventing Irritability and Temper Outbursts in Youth by Building Resilience
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Early childhood experiences and cognitive risk factors for anxiety symptoms among college students
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Conducting Ethical, Antiracist School-Based Research
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Chronic stress and anticipatory event-related potentials: the moderating role of resilience
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Bautista-Aranda, N., Contreras, L., & Cano‐Lozano, M. C. (2024) · Victims & Offenders · doi:10.1080/15564886.2024.2398586 · Cited by 8 · see citing works
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The Role of Emotion Regulation in Distinct Measures of Emotional Resilience
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The Indirect Effects of Trait Anxiety on Drug Use Via Emotion Dysregulation in a Low-Income Sample
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Do Adverse Childhood Experiences Make Us More Utilitarian in Moral Dilemmas?
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Resilience-related neural similarity during naturalistic movie watching
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- Authors
- Poole, J. C., Dobson, K. S., & Pusch, D.
- Affiliations
- University of Calgary (CA)
- Corresponding author
- Poole, Julia C.
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 217
- Pages
- 144-152
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2599014991
- Cited by
- 145
- References
- 75
- Citations by year
- 2026: 8 · 2025: 28 · 2024: 21 · 2023: 16 · 2022: 13 · 2021: 22 · 2020: 16 · 2019: 9 · 2018: 10 · 2017: 2
- FWCI
- 12.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Psychology › Clinical Psychology › Resilience and Mental Health
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- adverse childhood experiences, anxiety symptoms, emotional dysregulation, psychological resilience, moderated mediation, causes of anxiety, primary care patients, childhood adversity
- MeSH terms
- Emotional Adjustment, Adult Survivors of Child Adverse Events, Adult, Anxiety, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Risk Factors, Risk Assessment, Resilience, Psychological, Self Report
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