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Dietary Composition in the Treatment of Polycystic Ovary Syndrome: A Systematic Review to Inform Evidence-Based Guidelines
Abstract
While lifestyle management is recommended as first-line treatment of polycystic ovary syndrome (PCOS), the optimal dietary composition is unclear. The aim of this study was to compare the effect of different diet compositions on anthropometric, reproductive, metabolic, and psychological outcomes in PCOS. A literature search was conducted (Australasian Medical Index, CINAHL, EMBASE, Medline, PsycInfo, and EBM reviews; most recent search was performed January 19, 2012). Inclusion criteria were women with PCOS not taking anti-obesity medications and all weight-loss or maintenance diets comparing different dietary compositions. Studies were assessed for risk of bias. A total of 4,154 articles were retrieved and six articles from five studies met the a priori selection criteria, with 137 women included. A meta-analysis was not performed due to clinical heterogeneity for factors including participants, dietary intervention composition, duration, and outcomes. There were subtle differences between diets, with greater weight loss for a monounsaturated fat-enriched diet; improved menstrual regularity for a low-glycemic index diet; increased free androgen index for a high-carbohydrate diet; greater reductions in insulin resistance, fibrinogen, total, and high-density lipoprotein cholesterol for a low-carbohydrate or low-glycemic index diet; improved quality of life for a low-glycemic index diet; and improved depression and self-esteem for a high-protein diet. Weight loss improved the presentation of PCOS regardless of dietary composition in the majority of studies. Weight loss should be targeted in all overweight women with PCOS through reducing caloric intake in the setting of adequate nutritional intake and healthy food choices irrespective of diet composition.
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“Moran et al. (2013) reported that fiber and magnesium intake was associated with beneficial metabolic parameters in women with PCOS, thus affirming the composite effects of a fiber-rich, nutrient-wise diet lesser the chances of PCOS [128].”
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“Moran et al. (2013) reported that fiber and magnesium intake was associated with beneficial metabolic parameters in women with PCOS, thus affirming the composite effects of a fiber-rich, nutrient-wise diet lesser the chances of PCOS [128].”
From Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management (2025) · cites this paper as Moran et al. (2013)
Citations
Cites
(1998) · PsycEXTRA Dataset · doi:10.1037/e565682010-001 · Cited by 9,453
(2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.10.004 · Cited by 9,050
The Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group (2004) · Human Reproduction · doi:10.1093/humrep/deh098 · Cited by 6,138
(1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/68.4.899 · Cited by 2,722
Franks, S. (1995) · New England Journal of Medicine · doi:10.1056/nejm199509283331307 · Cited by 2,463
Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet
Shai, I., Schwarzfuchs, D., Henkin, Y., Shahar, D. R., Witkow, S., Greenberg, I., Golan, R., Fraser, D., Bolotin, A., Vardi, H., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0708681 · Cited by 2,143
Comparison of Weight-Loss Diets with Different Compositions of Fat, Protein, and Carbohydrates
Sacks, F. M., Bray, G. A., Carey, V. J., Smith, S. R., Ryan, D. H., Anton, S. D., McManus, K., Champagne, C. M., Bishop, L. M., Laranjo, N., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0804748 · Cited by 1,966
March, W. A., Moore, V. M., Willson, K. J., Phillips, D. I. W., Norman, R. J., & Davies, M. J. (2010) · Human Reproduction · doi:10.1093/humrep/dep399 · Cited by 1,799
Legro, R. S. (1999) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.1.165 · Cited by 1,743
Dansinger, M. L., Gleason, J. A., Griffith, J. L., Selker, H. P., & Schaefer, E. J. (2005) · JAMA · doi:10.1001/jama.293.1.43 · Cited by 1,726
Krauss, R. M., Eckel, R. H., Howard, B., Appel, L. J., Daniels, S. R., Deckelbaum, R. J., Erdman, J. W., Kris-Etherton, P., Goldberg, I. J., Kotchen, T. A., et al. (2000) · Circulation · doi:10.1161/01.cir.102.18.2284 · Cited by 1,458
Asunción, M., Calvo, R. M., Millán, J. L. S., Sancho, J., Ávila, S., & Escobar-Morreale, H. F. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.7.6682 · Cited by 1,328
Moran, L. J., Misso, M. L., Wild, R. A., & Norman, R. J. (2010) · Human Reproduction Update · doi:10.1093/humupd/dmq001 · Cited by 1,108
Self-citationDiamanti‐Kandarakis, E., Kouli, C., Bergiele, A. T., Filandra, F. A., Tsianateli, T. C., Spina, G., Zapanti, E. D., & Bartzis, M. I. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.11.6148 · Cited by 1,107
Andrology: Polycystic ovary syndrome: the spectrum of the disorder in 1741 patients
Balen, A. H., Conway, G. S., Kaltsas, G., Techatraisak, K., Manning, P. J., West, C., & Jacobs, H. S. (1995) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a136243 · Cited by 1,060
Gardner, C. D., Kiazand, A., Alhassan, S., Kim, S., Stafford, R. S., Balise, R. R., Kraemer, H. C., & King, A. C. (2007) · JAMA · doi:10.1001/jama.297.9.969 · Cited by 1,051
Nordmann, A. J., Nordmann, A., Briel, M., Keller, U., Yancy, W. S., Brehm, B. J., & Bucher, H. C. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.3.285 · Cited by 973
Yancy, W. S., Olsen, M. K., Guyton, J. R., Bakst, R. P., & Westman, E. C. (2004) · Annals of Internal Medicine · doi:10.7326/0003-4819-140-10-200405180-00006 · Cited by 946
A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome
Boomsma, C. M., Eijkemans, M. J. C., Hughes, E. G., Visser, G. H. A., Fauser, B. C. J. M., & Macklon, N. S. (2006) · Human Reproduction Update · doi:10.1093/humupd/dml036 · Cited by 852
Diets with high or low protein content and glycemic index for weight-loss maintenance
Larsen, T. M., Dalskov, S.-M., van Baak, M., Jebb, S. A., Papadaki, A., Pfeiffer, A. F. H., Martinez, J. A., Handjieva-Darlenska, T., Kunešová, M., Pihlsgård, M., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1007137 · Cited by 843
Asuncion, M. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.7.2434 · Cited by 791
Lifestyle changes in women with polycystic ovary syndrome
Lim, S. S., Hutchison, S. K., Van Ryswyk, E., Norman, R. J., Teede, H. J., & Moran, L. J. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007506.pub4 · Cited by 725
Self-citationPrevalence and Predictors of the Metabolic Syndrome in Women with Polycystic Ovary Syndrome
Ehrmann, D. A., Liljenquist, D. R., Kasza, K., Azziz, R., Legro, R. S., & Ghazzi, M. N. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1329 · Cited by 703
Barbieri, R. L., Makris, A., Randall, R. W., Daniels, G. H., Kistner, R. W., & Ryan, K. J. (1986) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-62-5-904 · Cited by 629
DeUgarte, C. M., Bartolucci, A. A., & Azziz, R. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.11.070 · Cited by 589
Moran, L. J., Noakes, M., Clifton, P. M., Tomlinson, L., & Norman, R. J. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020815 · Cited by 530
Self-citationDietary glycemic index and obesity
Ludwig, D. S. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.2.280s · Cited by 521
Noakes, M., Keogh, J. B., Foster, P. R., & Clifton, P. M. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.6.1298 · Cited by 483
Self-citationMoran, L. J., Pasquali, R., Teede, H. J., Hoeger, K. M., & Norman, R. J. (2009) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.09.018 · Cited by 444
Self-citationFreedman, M. R., King, J., & Kennedy, E. (2001) · Obesity Research · doi:10.1038/oby.2001.113 · Cited by 421
de Groot, P. C. M., Dekkers, O. M., Romijn, J. A., Dieben, S. W. M., & Helmerhorst, F. M. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmr001 · Cited by 394
Low glycaemic index or low glycaemic load diets for overweight and obesity
Thomas, D., Elliott, E. J., & Baur, L. A. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005105.pub2 · Cited by 386
Abdominal adiposity and the polycystic ovary syndrome
Escobar-Morreale, H. F., & Millán, J. L. S. (2007) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2007.07.003 · Cited by 386
Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline
Teede, H. J., Misso, M. L., Deeks, A. A., Moran, L. J., Stuckey, B. G. A., Wong, J. L. A., Norman, R. J., Costello, M. F., & Groups, O. B. O. T. G. D. (2011) · Medical Journal of Australia · doi:10.5694/mja11.10915 · Cited by 379
Self-citationKIDDY, D. S., SHARP, P. S., WHITE, D. M., SCANLON, M. F., MASON, H. D., BRAY, C. S., POLSON, D. W., REED, M. J., & FRANKS, S. (1990) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1990.tb00857.x · Cited by 364
Cronin, L., Guyatt, G. H., Griffith, L. E., Wong, E. Y. L., Azziz, R., Futterweit, W., Cook, D., & Dunaif, A. E. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.6.4990 · Cited by 355
Prevalence and Characteristics of the Polycystic Ovary Syndrome in Overweight and Obese Women
Álvarez‐Blasco, F., Botella-Carretero, J. I., Millán, J. L. S., & Escobar-Morreale, H. F. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.19.2081 · Cited by 352
Anxiety and depression in polycystic ovary syndrome: a systematic review and meta-analysis
Barry, J. A., Kuczmierczyk, A. R., & Hardiman, P. J. (2011) · Human Reproduction · doi:10.1093/humrep/der197 · Cited by 336
Dietary protein intake and renal function
Martin, W. F., Armstrong, L. E., & Rodriguez, N. R. (2005) · Nutrition & Metabolism · doi:10.1186/1743-7075-2-25 · Cited by 308
Rutter, M. K., Meigs, J. B., SULLIVAN, L. M., D’Agostino, R. B., & Wilson, P. W. F. (2005) · Diabetes · doi:10.2337/diabetes.54.11.3252 · Cited by 307
Dietary Protein: An Essential Nutrient For Bone Health
Bonjour, J. (2005) · Journal of the American College of Nutrition · doi:10.1080/07315724.2005.10719501 · Cited by 295
Smith, R. N., Mann, N. J., Braue, A., Mäkeläinen, H., & Varigos, G. A. (2007) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2007.01.046 · Cited by 294
Lifestyle changes in women with polycystic ovary syndrome
Moran, L. J., Hutchison, S. K., Norman, R. J., & Teede, H. J. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007506.pub3 · Cited by 292
Self-citationBouché, C., Rizkalla, S. W., Luo, J., Vidal, H., Véronèse, A., Pacher, N., Fouquet, C., Lang, V., & Slama, G. (2002) · Diabetes Care · doi:10.2337/diacare.25.5.822 · Cited by 287
Nutritional Recommendations and Principles for Individuals With Diabetes Mellitus: 1986
AMERICAN DIABETES ASSOCIATION (1987) · Diabetes Care · doi:10.2337/diacare.10.1.126 · Cited by 275
Stamets, K., Taylor, D. S., Kunselman, A., Demers, L. M., Pelkman, C. L., & Legro, R. S. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.08.023 · Cited by 252
Meta-analysis of cardiovascular disease risk markers in women with polycystic ovary syndrome
Toulis, K. A., Goulis, D. G., Mintziori, G., Kintiraki, E., Eukarpidis, E., Mouratoglou, S., Pavlaki, A., Stergianos, S., Poulasouchidou, M., Tzellos, T., et al. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmr025 · Cited by 229
Marsh, K. A., Steinbeck, K. S., Atkinson, F. S., Petocz, P., & Brand-Miller, J. C. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29261 · Cited by 228
Self-citationJohnston, C. S., Tjonn, S. L., & Swan, P. D. (2004) · Journal of Nutrition · doi:10.1093/jn/134.3.586 · Cited by 215
Deeks, A. A., Gibson-Helm, M. E., Paul, E., & Teede, H. J. (2011) · Human Reproduction · doi:10.1093/humrep/der071 · Cited by 202
Self-citationRole of Diet in the Treatment of Polycystic Ovary Syndrome
Douglas, C. C., Gower, B. A., Darnell, B. E., Ovalle, F., Oster, R. A., & Azziz, R. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.08.045 · Cited by 170
Moran, L. J., Noakes, M., Clifton, P. M., Wittert, G. A., Williams, G., & Norman, R. J. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.1.77 · Cited by 141
Self-citationThe management of insulin resistance in polycystic ovary syndrome
Teede, H. J., Hutchison, S. K., & Zoungas, S. (2007) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2007.08.001 · Cited by 135
Self-citationMoran, L., Gibson-Helm, M., Teede, H., & Deeks, A. (2010) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.3109/01674820903477593 · Cited by 127
Self-citationGardner, C. D., Kim, S., Bersamin, A., Dopler-Nelson, M., Otten, J., Oelrich, B., & Cherin, R. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29468 · Cited by 107
Galletly, C., Moran, L., Noakes, M., Clifton, P., Tomlinson, L., & Norman, R. (2007) · Appetite · doi:10.1016/j.appet.2007.03.222 · Cited by 103
Self-citationLong-term effects of provided low and high glycemic load low energy diets on mood and cognition
Cheatham, R. A., Roberts, S. B., Das, S. K., Gilhooly, C. H., Golden, J. K., Hyatt, R. R., Lerner, D., Saltzman, E. J., & Lieberman, H. R. (2009) · Physiology & Behavior · doi:10.1016/j.physbeh.2009.06.015 · Cited by 70
Effects of increased dietary protein-to-carbohydrate ratios in women with polycystic ovary syndrome
Sørensen, L. B., Søe, M., Halkier, K. H., Stigsby, B., & Astrup, A. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.020693 · Cited by 70
Relation of nutrients and hormones in polycystic ovary syndrome
Kasim-Karakas, S. E., Cunningham, W., & Tsodikov, A. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.3.688 · Cited by 57
Yackobovitch-Gavan, M., Nagelberg, N., Demol, S., Phillip, M., & Shalitin, S. (2008) · Appetite · doi:10.1016/j.appet.2008.06.010 · Cited by 37
Katcher, H. I., Kunselman, A. R., Dmitrović, R., Demers, L. M., Gnatuk, C. L., Kris‐Etherton, P. M., & Legro, R. S. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.01.035 · Cited by 32
Wang, P., Holst, C., Astrup, A. V., Bouwman, F. G., van Otterdijk, S. D., Wodzig, W. K. W. H., Andersen, M. R., van Baak, M. A., Rasmussen, L. G., Martínez, J. A., et al. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511002583 · Cited by 24
Research works printed but not linked: 1
- Skov, 1996, The effect of a low-fat, high protein vs a low-fat, high carbohydrate diet on cardiovascular risk factors in obese subjects, Int J Obesity, 20, 5547
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Metadata
- Authors
- Moran, L. J., Ko, H., Misso, M., Marsh, K., Noakes, M., Talbot, M., Frearson, M., Thondan, M., Stepto, N., & Teede, H. J.
- Affiliations
- The University of Adelaide (AU)
- Corresponding author
- Moran, Lisa J.
- Venue
- Journal of the Academy of Nutrition and Dietetics
- Publisher
- Elsevier BV
- Published
- 2013-04
- Volume
- 113
- Issue
- 4
- Pages
- 520-545
- ISSN
- 2212-2672 (ISSN-L)
- OpenAlex
- W2133253662
- Cited by
- 259
- References
- 64
- Citations by year
- 2026: 13 · 2025: 25 · 2024: 24 · 2023: 16 · 2022: 18 · 2021: 28 · 2020: 16 · 2019: 17 · 2018: 21 · 2017: 15 · 2016: 17 · 2015: 27 · 2014: 15 · 2013: 6
- FWCI
- 3.51
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the Academy of Nutrition and Dietetics (publishedVersion)
- PubMed (publishedVersion)
- Victoria University Research Repository (Victoria University) (submittedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- polycystic ovary syndrome, diet composition, weight loss diet, low glycemic index diet, low-carbohydrate diet, high-protein diet, insulin resistance, menstrual cycle regularity, free androgen index, quality of life, depression, self-esteem, lifestyle management, overweight women
- MeSH terms
- Androgens, Energy Intake, Diet, Dietary Carbohydrates, Dietary Fats, Dietary Proteins, Female, Humans, Obesity, Polycystic Ovary Syndrome, Quality of Life, United States, Weight Loss, Treatment Outcome, Guidelines as Topic, Glycemic Index, Overweight
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