Cited by 31Medicinal Plants and NeuroprotectionAlzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Dietary intervention with edible medicinal plants and derived products for prevention of Alzheimer's disease: A compendium of time-tested strategy

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Peng, Yu, Tao, Hongxun, Wang, Shengpeng, Xiao, Jianbo, Wang, Yitao, Su, Huanxing·2021·Journal of Functional Foods

Abstract

Alzheimer’s disease (AD) is acccounting for over 50% of all cases of dementia worldwide. Currently there are no effective treatments available for AD. Plant-based medications and dietary interventions have attracted increasing research interest as an alternative strategy for the protection and treatment of AD. Thereby, this review aims to summarize different medical interventions with dietary materials such as edible medicinal plants and ways to capitalize on the therapeutic advantages of their components to provide an alternative approach to enhance their long-term pleiotropic benefits in AD. Given the established mechanisms in AD pathogenesis, we elucidate different pathophysiological changes associated with lowering the disease incidence with these mainly plant-based dietary materials, providing laboratory evidence on the feasibility and potential of dietary intervention in the prevention and treatment of AD. In particular, we highly recommend the concept of dietary intervention as an alternative or supplementary therapeutic strategy.

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Authors
Peng, Y., Tao, H., Wang, S., Xiao, J., Wang, Y., & Su, H.
Affiliations
University of Macau (MO)
Corresponding author
Su, Huanxing
Venue
Journal of Functional Foods
Publisher
Elsevier BV
Published
2021-06
Volume
81
Pages
104463
ISSN
1756-4646 (ISSN-L)
OpenAlex
W3156628315
Cited by
31
References
147
Citations by year
2026: 1 · 2025: 9 · 2024: 6 · 2023: 9 · 2022: 3 · 2021: 3
FWCI
5.92
Type
journal article
Language
en
Open access
Locations
  • Journal of Functional Foods (publishedVersion, cc-by-nc-nd)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Universidade de Macau (MYRG2018-00242-ICMS, MYRG2019-00160-ICMS)
  • University of Macau Institute of Chinese Medical Science
  • Science and Technology Development Fund (0049/2019/A1)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plants and Neuroprotection
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords
Alzheimer's disease, dietary intervention, edible medicinal plants, plant products, dementia prevention, plant-derived drugs, Alzheimer's disease pathogenesis

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