Microglia and neuroinflammation: a pathological perspective

Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359 · see citing works

Inflammation and Alzheimer’s disease

Akiyama, H. (2000) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00124-x · Cited by 4,514 · see citing works

Innate Immunity

Medzhitov, R. M., & Janeway, C. A. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008033430506 · Cited by 1,827 · see citing works

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease.

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Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR

McGeer, P. L., Itagaki, S., Tago, H., & McGeer, E. G. (1987) · Neuroscience Letters · doi:10.1016/0304-3940(87)90696-3 · Cited by 836 · see citing works

APPSW Transgenic Mice Develop Age-related Aβ Deposits and Neuropil Abnormalities, but no Neuronal Loss in CA1

IRIZARRY, M. C., MCNAMARA, M., FEDORCHAK, K., HSIAO, K., & HYMAN, B. T. (1997) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199709000-00002 · Cited by 649 · see citing works

Microglial response to amyloid plaques in APPsw transgenic mice.

Frautschy, S. A., Yang, F., Irrizarry, M., Hyman, B. T., Saido, T. C., Hsiao, K., & Cole, G. M. (1998) · Europe PMC (PubMed Central) · Cited by 592 · see citing works

Neuroinflammation in Alzheimer's disease and prion disease

Eikelenboom, P., Bate, C., van Gool, W. A., Hoozemans, J. J. M., Rozemüller, A. J. M., Veerhuis, R., & Williams, A. (2002) · Glia · doi:10.1002/glia.10146 · Cited by 402 · see citing works

Rats and mice exhibit distinct inflammatory reactions after spinal cord injury

Sroga, J. M., Jones, T. B., Kigerl, K. A., McGaughy, V. M., & Popovich, P. G. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10736 · Cited by 369 · see citing works

Fibrillar β-Amyloid Induces Microglial Phagocytosis, Expression of Inducible Nitric Oxide Synthase, and Loss of a Select Population of Neurons in the Rat CNS<i>In Vivo</i>

Weldon, D. T., Rogers, S. D., Ghilardi, J. R., Finke, M. P., Cleary, J. P., O’Hare, E., Esler, W. P., Maggio, J. E., & Mantyh, P. W. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-06-02161.1998 · Cited by 348 · see citing works

Cytokine mRNA Profiles in Contused Spinal Cord and Axotomized Facial Nucleus Suggest a Beneficial Role for Inflammation and Gliosis

Streit, W. J., Semple‐Rowland, S. L., Hurley, S. D., Miller, R. C., Popovich, P. G., & Stokes, B. T. (1998) · Experimental Neurology · doi:10.1006/exnr.1998.6835 · Cited by 344 · see citing works

Microglia and Alzheimer's disease pathogenesis

Streit, W. J. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20093 · Cited by 335 · see citing works

Microglia in human immunodeficiency virus‐associated neurodegeneration

Garden, G. A. (2002) · Glia · doi:10.1002/glia.10155 · Cited by 206 · see citing works

EVIDENCE FOR AN EARLY INFLAMMATORY RESPONSE IN THE CENTRAL NERVOUS SYSTEM OF MICE WITH SCRAPIE

Betmouni, S., Perry, V. H., & Gordon, J. L. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00212-6 · Cited by 196 · see citing works

Atypical inflammation in the central nervous system in prion disease

Perry, V. H., Cunningham, C. M., & Boche, D. (2002) · Current Opinion in Neurology · doi:10.1097/00019052-200206000-00020 · Cited by 180 · see citing works

The Brain's Immune System

Streit, W. J., & Colton, C. A. (1995) · Scientific American · doi:10.1038/scientificamerican1195-54 · Cited by 171 · see citing works

Interferon γ, interleukin 4 and transforming growth factor β in experimental autoimmune encephalomyelitis in lewis rats: Dynamics of cellular mrna expression in the central nervous system and lymphoid cells

Issazadeh‐Navikas, S., Mustafa, M., Ljungdahl, Å., Höjeberg, B., Dagerlind, Å., Elde, R., & Olsson, T. P. (1995) · Journal of Neuroscience Research · doi:10.1002/jnr.490400503 · Cited by 158 · see citing works

Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid.

Frautschy, S. A., Cole, G. M., & Baird, A. (1992) · PubMed Central · Cited by 157 · see citing works

Protein accumulation in traumatic brain injury

Smith, D. H., Uryu, K., Saatman, K., Trojanowski, J., & McIntosh, T. (2007) · Neuromolecular medicine · doi:10.1385/nmm:4:1-2:59 · Cited by 155 · see citing works

Microglia from Creutzfeldt-Jakob disease-infected brains are infectious and show specific mRNA activation profiles

Baker, C. A., Martin, D., & Manuelidis, L. (2002) · Journal of Virology · doi:10.1128/jvi.76.21.10905-10913.2002 · Cited by 128 · see citing works

T Cells Infiltrate the Brain in Murine and Human Transmissible Spongiform Encephalopathies

Lewicki, H. A., Tishon, A., Homann, D., Mazarguil, H., Laval, F., Asensio, V. C., Campbell, I. L., DeArmond, S. J., Coon, B., Teng, C., et al. (2003) · Journal of Virology · doi:10.1128/jvi.77.6.3799-3808.2003 · Cited by 65 · see citing works

Altered β-APP Metabolism After Head Injury and its Relationship to the Aetiology of Alzheimer’s Disease

Graham, D. I., Gentleman, S., Nicoll, J. A. R., Royston, M. C., McKenzie, J. E., Roberts, G. W., & Griffin, W. S. T. (1996) · Springer eBooks · doi:10.1007/978-3-7091-9465-2_17 · Cited by 60 · see citing works

Principles of Neuronal Regeneration

Kreutzberg, G. W. (1996) · Springer eBooks · doi:10.1007/978-3-7091-9465-2_18 · Cited by 41 · see citing works

Is There a Genetic Basis for the Deposition of β-Amyloid After Fatal Head Injury?

Graham, D. I., Gentleman, S. M., Nicoll, J. A. R., Royston, M. C., McKenzie, J. E., Roberts, G. W., Mrak, R. E., & Griffin, W. S. T. (1999) · Cellular and Molecular Neurobiology · doi:10.1023/a:1006956306099 · Cited by 21 · see citing works

Lesioning of the inferior olive using a ventral surgical approach

Ito, K., Ishikawa, Y., Skinner, R. D., Mrak, R. E., Morrison‐Bogorad, M., Mukawa, J., & Griffin, W. S. T. (1997) · Molecular and Chemical Neuropathology · doi:10.1007/bf02815128 · Cited by 10 · see citing works

Neuroinflammation in Alzheimer's disease: current evidence and future directions

Calsolaro, V., & Edison, P. (2016) · Alzheimer's &amp; Dementia · doi:10.1016/j.jalz.2016.02.010 · Cited by 1,726 · see citing works

Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease.

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Microglial signatures and their role in health and disease

Butovsky, O., & Weiner, H. L. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0057-5 · Cited by 1,046 · see citing works

ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease

Simpson, D. S. A., & Oliver, P. L. (2020) · Antioxidants · doi:10.3390/antiox9080743 · Cited by 1,044 · see citing works

Primary Open-Angle Glaucoma

Kwon, Y. H., Fingert, J. H., Kuehn, M. H., & Alward, W. L. M. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0804630 · Cited by 892 · see citing works

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression

Gao, H., & Hong, J. (2008) · Trends in Immunology · doi:10.1016/j.it.2008.05.002 · Cited by 822 · see citing works

The role of microglia in amyloid clearance from the AD brain

Lee, C. Y. D., & Landreth, G. E. (2010) · Journal of Neural Transmission · doi:10.1007/s00702-010-0433-4 · Cited by 701 · see citing works

CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar Aβ-Stimulated Microglial Activation

Reed-Geaghan, E. G., Savage, J. C., Hise, A. G., & Landreth, G. E. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3158-09.2009 · Cited by 591 · see citing works

Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer’s disease

Cai, Z., Hussain, M. D., & Yan, L.-J. (2014) · International Journal of Neuroscience · doi:10.3109/00207454.2013.833510 · Cited by 583 · see citing works

Pivotal role of TLR4 receptors in alcohol-induced neuroinflammation and brain damage

Alfonso-Loeches, S., Pascual-Lucas, M., Blanco, A. M., Sanchez-Vera, I., & Guerri, C. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0976-10.2010 · Cited by 579 · see citing works

Microglial cell dysregulation in brain aging and neurodegeneration

von Bernhardi, R., Eugenín-von Bernhardi, L., & Eugenín, J. (2015) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2015.00124 · Cited by 556 · see citing works

A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures

Rossignol, D. A., & Frye, R. E. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.165 · Cited by 545 · see citing works

Polystyrene nanoplastics penetrate across the blood-brain barrier and induce activation of microglia in the brain of mice

Shan, S., Zhang, Y., Zhao, H., Zeng, T., & Zhao, X. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.134261 · Cited by 532 · see citing works

Deficient autophagy in microglia impairs synaptic pruning and causes social behavioral defects

Kim, H.-J., Cho, M.-H., Shim, W. H., Kim, J. K., Jeon, E.-Y., Kim, D.-H., & Yoon, S.-Y. (2017) · Molecular Psychiatry · doi:10.1038/mp.2016.103 · Cited by 475 · see citing works

Neuroinflammation in the pathogenesis of Alzheimer’s disease. A rational framework for the search of novel therapeutic approaches

Morales, I., Guzmán-Martínez, L., Cerda-Troncoso, C., Farías, G. A., & Maccioni, R. B. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00112 · Cited by 490 · see citing works

The role of microglia in retinal neurodegeneration: Alzheimer’s disease, parkinson, and glaucoma.

Ramirez, A. I., de Hoz, R., Salobrar-Garcia, E., Salazar, J. J., Rojas, B., Ajoy, D., López-Cuenca, I., Rojas, P., Triviño, A., & Ramírez, J. M. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00214 · Cited by 466 · see citing works

Microglial Phagocytosis of Fibrillar β-Amyloid through a β1Integrin-Dependent Mechanism

Koenigsknecht-Talboo, J., & Landreth, G. E. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2557-04.2004 · Cited by 444 · see citing works

The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinson's disease

Wang, S., Yuan, Y., Chen, N., & Wang, H. (2018) · International Immunopharmacology · doi:10.1016/j.intimp.2018.12.019 · Cited by 447 · see citing works

Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline

vom Berg, J., Prokop, S., Miller, K. R., Obst, J., Kälin, R. E., Lopategui-Cabezas, I., Wegner, A., Mair, F., Schipke, C. G., Peters, O., et al. (2012) · Nature Medicine · doi:10.1038/nm.2965 · Cited by 416 · see citing works

Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome

Cho, M.-H., Cho, K., Kang, H.-J., Jeon, E.-Y., Kim, H.-S., Kwon, H.-J., Kim, H.-M., Kim, D.-H., & Yoon, S.-Y. (2014) · Autophagy · doi:10.4161/auto.29647 · Cited by 395 · see citing works

The P2X ₇ Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X ₇ R Pore

Monif, M., Reid, C. A., Powell, K. L., Smart, M. L., & Williams, D. A. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.5512-08.2009 · Cited by 374 · see citing works

Critical role of TLR4 response in the activation of microglia induced by ethanol

Fernandez-Lizarbe, S., Pascual, M., & Guerri, C. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803590 · Cited by 373 · see citing works

Neuroinvasion, neurotropic, and neuroinflammatory events of SARS-CoV-2: understanding the neurological manifestations in COVID-19 patients

Yachou, Y., Idrissi, A. E., Belapasov, V., & BenAli, S. A. (2020) · Neurological Sciences · doi:10.1007/s10072-020-04575-3 · Cited by 374 · see citing works

Imaging robust microglial activation after lipopolysaccharide administration in humans with PET

Sandiego, C. M., Gallezot, J.-D., Pittman, B., Nabulsi, N., Lim, K., Lin, S.-F., Matuskey, D., Lee, J.-Y., O’Connor, K. C., Huang, Y., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1511003112 · Cited by 356 · see citing works

Blood–Brain Barrier Pathology in Alzheimer's and Parkinson's Disease: Implications for Drug Therapy

Desai, B. S., Monahan, A. J., Carvey, P. M., & Hendey, B. (2007) · Cell Transplantation · doi:10.3727/000000007783464731 · Cited by 339 · see citing works

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

Njie, E. G., Boelen, E., Stassen, F. R., Steinbusch, H. W. M., Borchelt, D. R., & Streit, W. J. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2010.05.008 · Cited by 335 · see citing works

Acute and Chronic Stress-Induced Disturbances of Microglial Plasticity, Phenotype and Function

Walker, F. R., Nilsson, M., & Jones, K. (2013) · Current Drug Targets · doi:10.2174/13894501113149990208 · Cited by 324 · see citing works

HMGB1: A Common Biomarker and Potential Target for TBI, Neuroinflammation, Epilepsy, and Cognitive Dysfunction

Paudel, Y. N., Shaikh, M. F., Chakraborti, A., Kumari, Y., Aledo-Serrano, Á., Aleksovska, K., Alvim, M. K. M., & Othman, I. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00628 · Cited by 311 · see citing works

Oxidative Stress in Autism Spectrum Disorder

Bjørklund, G., Meguid, N. A., El-Bana, M. A., Tinkov, A. A., Saad, K., Dadar, M., Hemimi, M., Skalny, A. V., Hosnedlová, B., Kizek, R., et al. (2020) · Molecular Neurobiology · doi:10.1007/s12035-019-01742-2 · Cited by 323 · see citing works

Neuroinflammation and white matter pathology in schizophrenia: systematic review

Najjar, S., & Pearlman, D. M. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.04.041 · Cited by 317 · see citing works

Privileged Structures: Efficient Chemical “Navigators” toward Unexplored Biologically Relevant Chemical Spaces

Kim, J., Kim, H., & Park, S. B. (2014) · Journal of the American Chemical Society · doi:10.1021/ja508343a · Cited by 308 · see citing works

Postoperative cognitive dysfunction – current preventive strategies

Kotekar, N., Shenkar, A., & Nagaraj, R. (2018) · Clinical Interventions in Aging · doi:10.2147/cia.s133896 · Cited by 309 · see citing works

The effects of microglia-associated neuroinflammation on Alzheimer’s disease

Wang, C., Zong, S., Cui, X., Wang, X., Wu, S., Wang, L., Liu, Y., & Lu, Z. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1117172 · Cited by 318 · see citing works

Excessive Extracellular Volume Reveals a Neurodegenerative Pattern in Schizophrenia Onset

Pasternak, O., Westin, C., Sylvain Bouix, A., Seidman, L. J., Goldstein, J. M., Woo, T.-U. W., Petryshen, T. L., Mesholam‐Gately, R. I., McCarley, R. W., Kikinis, R., et al. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.2904-12.2012 · Cited by 306 · see citing works

Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease

Biron, K. E., Dickstein, D. L., Gopaul, R., & Jefferies, W. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023789 · Cited by 300 · see citing works

Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin

Rosales‐Corral, S., Acuña-Castroviejo, D., Coto‐Montes, A. M., Boga, J. A., Manchester, L. C., Fuentes‐Broto, L., Korkmaz, A., Ma, S., Tan, D. X., & Reiter, R. J. (2011) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2011.00937.x · Cited by 293 · see citing works

Neuroinflammation and microglia: considerations and approaches for neurotoxicity assessment

Harry, G. J., & Kraft, A. D. (2008) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425255.4.10.1265 · Cited by 292 · see citing works

NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration

Qin, L., & Crews, F. T. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-5 · Cited by 290 · see citing works

Recent Developments in TSPO PET Imaging as A Biomarker of Neuroinflammation in Neurodegenerative Disorders

Werry, E. L., Bright, F., Piguet, O., Ittner, L. M., Halliday, G. M., Hodges, J. R., Kiernan, M. C., Loy, C. T., Kril, J. J., & Kassiou, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20133161 · Cited by 282 · see citing works

Puberty and adolescence as a time of vulnerability to stressors that alter neurobehavioral processes

Holder, M. K., & Blaustein, J. D. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2013.10.004 · Cited by 279 · see citing works

Immune cell involvement in dorsal root ganglia and spinal cord after chronic constriction or transection of the rat sciatic nerve

Hu, P., Bembrick, A. L., Keay, K. A., & McLachlan, E. M. (2006) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2006.10.013 · Cited by 279 · see citing works

Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease

Sobue, A., Komine, O., Hara, Y., Endo, F., Mizoguchi, H., Watanabe, S., Murayama, S., Saito, T., Saido, T. C., Sahara, N., et al. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-020-01099-x · Cited by 253 · see citing works

The neuropathology, pathophysiology and genetics of multiple system atrophy

Ahmed, Z., Asi, Y. T., Sailer, A., Lees, A. J., Houlden, H., Révész, T., & Holton, J. L. (2011) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2011.01234.x · Cited by 267 · see citing works

Aging‐dependent changes of microglial cells and their relevance for neurodegenerative disorders

Von Bernhardi, R., Tichauer, J. E., & Eugenín, J. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06537.x · Cited by 258 · see citing works

The Role of p38 MAPK and Its Substrates in Neuronal Plasticity and Neurodegenerative Disease

Corrêa, S. A. L., & Eales, K. L. (2012) · Journal of Signal Transduction · doi:10.1155/2012/649079 · Cited by 258 · see citing works

Neuronal and microglial mechanisms of neuropathic pain

Zhuo, M., Wu, G., & Wu, L. (2011) · Molecular Brain · doi:10.1186/1756-6606-4-31 · Cited by 256 · see citing works

Shaping Neuronal Fate: Functional Heterogeneity of Direct Microglia-Neuron Interactions

Cserép, C., Pósfai, B., & Dénes, Á. (2021) · Neuron · doi:10.1016/j.neuron.2020.11.007 · Cited by 256 · see citing works

Neonatal infection-induced memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition

Bilbo, S. D., Biedenkapp, J. C., Der-Avakian, A., Watkins, L. R., Rudy, J. W., & Maier, S. F. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1748-05.2005 · Cited by 251 · see citing works

Cutting Edge: TLR2-Mediated Proinflammatory Cytokine and Chemokine Production by Microglial Cells in Response to Herpes Simplex Virus

Aravalli, R. N., Hu, S., Rowen, T. N., Palmquist, J. M., & Lokensgard, J. R. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.7.4189 · Cited by 251 · see citing works

Neuroinflammation in animal models of traumatic brain injury

Chiu, C., Liao, Y.-E., Yang, L.-Y., Wang, J.-Y., Tweedie, D., Karnati, H. K., Greig, N. H., & Wang, J. (2016) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2016.06.018 · Cited by 248 · see citing works

TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice

Frank, S., Burbach, G. J., Bonin, M., Walter, M., Streit, W., Bechmann, I., & Deller, T. (2008) · Glia · doi:10.1002/glia.20710 · Cited by 247 · see citing works

TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice

Marrone, M. C., Morabito, A., Giustizieri, M., Chiurchiù, V., Leuti, A., Mattioli, M., Marinelli, S., Riganti, L., Lombardi, M., Murana, E., et al. (2017) · Nature Communications · doi:10.1038/ncomms15292 · Cited by 247 · see citing works

Sex differences in pain

Mapplebeck, J. C. S., Beggs, S., & Salter, M. W. (2015) · Pain · doi:10.1097/j.pain.0000000000000389 · Cited by 243 · see citing works

Microglial Dynamics During Human Brain Development

Menassa, D. A., & Gómez‐Nicola, D. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01014 · Cited by 238 · see citing works

Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid

Nichol, K. E., Poon, W. W., Parachikova, A. I., Cribbs, D. H., Glabe, C. G., & Cotman, C. W. (2008) · Journal of Neuroinflammation · doi:10.1186/1742-2094-5-13 · Cited by 241 · see citing works

Lactate Shuttles in Neuroenergetics—Homeostasis, Allostasis and Beyond

Mason, S. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00043 · Cited by 240 · see citing works

Cathepsin B plays a critical role in inducing Alzheimer’s disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice

Wu, Z., Ni, J., Liu, Y., Teeling, J. L., Takayama, F., Collcutt, A. W., Ibbett, P., & Nakanishi, H. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.06.002 · Cited by 239 · see citing works

Microglia: A new frontier for synaptic plasticity, learning and memory, and neurodegenerative disease research

Morris, G. P., Clark, I. A., Zinn, R., & Vissel, B. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.07.002 · Cited by 236 · see citing works

TNF-alpha-induced microglia activation requires miR-342: Impact on NF-kB signaling and neurotoxicity

Brás, J. P., Bravo, J., Freitas, J., Barbosa, M. A., Santos, S. G., Summavielle, T., & Almeida, M. I. (2020) · Cell Death &amp; Disease · doi:10.1038/s41419-020-2626-6 · Cited by 236 · see citing works

Anti-neuroinflammatory Potential of Natural Products in Attenuation of Alzheimer’s Disease

Shal, B., Ding, W., Ali, H., Kim, Y. S., & Khan, S. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00548 · Cited by 234 · see citing works

Neuroprotective Natural Products for Alzheimer’s Disease

Chen, X., Drew, J., Berney, W., & Lei, W. (2021) · Cells · doi:10.3390/cells10061309 · Cited by 236 · see citing works

Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin

Fiala, M., Liu, P. T., Monteros, A. E. D. L., Rosenthal, M. J., Bernard, G. W., Ringman, J. M., Sayre, J. W., Zhang, L., Zaghi, J., Dejbakhsh, S., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701267104 · Cited by 233 · see citing works

Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson’s disease

George, S., Rey, N. L., Tyson, T., Esquibel, C., Meyerdirk, L., Schulz, E., Pierce, S., Burmeister, A. R., Madaj, Z., Steiner, J. A., et al. (2019) · Molecular Neurodegeneration · doi:10.1186/s13024-019-0335-3 · Cited by 229 · see citing works

Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials

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Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice

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