Cited by 176Microbial Metabolites in Food BiotechnologyPolysaccharides Composition and ApplicationsPolysaccharides and Plant Cell Walls

Oligosaccharides from land plants and algae: Production and applications in therapeutics and biotechnology

Courtois, Josiane·2009·Current Opinion in Microbiology

Abstract

Since the past decades, oligosaccharides are considered for their potential biological activities. To exploit them, it was essential to obtain pure molecules in large amounts. Several strategies were developed to produce specific sugar sequences with specific substitution patterns from land plants and algae polysaccharides. Then, pure oligosaccharides were analyzed for their potential biological activities and relations between oligomers structure and function were tackled. First they can be health beneficial molecules when they are added to the diet to enhance the growth of probiotic bacteria, in that case, oligomers that resist to the digestive process are used as specific substrate for the growth of health beneficial bacteria. In other cases, oligomers have to interact with receptors on cells. In this instance, a specific conformation is needed to allow the sugar sequence to establish specific linkages with the receptor. So, to be adapted to the receptor, the oligosaccharides have to present specific groups to the receptor, there, the polymerization degree of oligosaccharides as well as the flexibility of the glycosidic linkages has to be considered.

Integrity signals

Registry

Crossref · 10.1016/j.mib.2009.04.007

Cites

125 of 125 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Some prebiotics naturally occurring in seaweeds are saccharides with a degree of polymerization within 2 and 9 (sometimes within 8 and 20), and some researchers consider up to 25 sugar residues.

    “Some prebiotics (or prebiotic candidates) naturally occurring in seaweeds are saccharides presenting a degree of polymerization (DP) within 2 and 9 (sometimes within 8 and 20). Some researchers consider up to 25 sugar residues [122].”
  • The free radical technique is effective for hydrolysis of polysaccharides and does not affect the structure of compounds when correctly performed.

    “The use of free radicals is another effective technique for the hydrolysis of polysaccharides, since it does not affect the structure of the compounds when it is correctly performed [122].”
  • Phosphoric acid is capable of effectively hydrolyzing polysaccharides of Chlorella vulgaris and Spirulina platensis, mostly composed of uronic acids, giving rise to oligosaccharides with potential prebiotic properties.

    “phosphoric acid is capable of effectively hydrolyzing polysaccharides of some algae species, such as Chlorella vulgaris and Spirulina platensis [128], mostly composed of uronic acids and giving rise to interesting oligosaccharides with potential prebiotic properties [122].”

Cites

Flagged first, then by citations

2 of the 127 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Courtois, J.
Affiliations
Université de Picardie Jules Verne (FR)
Corresponding author
Courtois, Josiane
Venue
Current Opinion in Microbiology
Publisher
Elsevier BV
Published
2009-06
Volume
12
Issue
3
Pages
261-273
ISSN
1369-5274 (ISSN-L)
OpenAlex
W2014100699
Cited by
176
References
127
Citations by year
2026: 5 · 2025: 3 · 2024: 10 · 2023: 16 · 2022: 10 · 2021: 9 · 2020: 17 · 2019: 7 · 2018: 12 · 2017: 13 · 2016: 15 · 2015: 17 · 2014: 9 · 2013: 10 · 2012: 10
FWCI
0.87
Type
journal article
Language
en
Open access
closed
Locations
  • Current Opinion in Microbiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
Keywords
oligosaccharides, land plants, algae, polysaccharide degradation, oligosaccharide production, structure-function relationship, probiotic bacteria, prebiotics, receptor binding, degree of polymerization, therapeutics, biotechnology
MeSH terms
Biotechnology, Humans, Oligosaccharides, Plants, Therapeutics, Eukaryota

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review