Synaptic slaughter in Alzheimer's disease

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity

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Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease

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Neuron numbers and dendritic extent in normal aging and Alzheimer’s disease

Coleman, P. D., & Flood, D. G. (1987) · Neurobiology of Aging · doi:10.1016/0197-4580(87)90127-8 · Cited by 772 · see citing works

A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads

Braak, F., Braak, H., & Mandelkow, E. (1994) · Acta Neuropathologica · doi:10.1007/bf00293315 · Cited by 769 · see citing works

The molecular machinery for secretion is conserved from yeast to neurons.

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A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter

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Dendritic Growth in the Aged Human Brain and Failure of Growth in Senile Dementia

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Quantitative assessment of cortical synaptic density in Alzheimer's disease

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Clathrin Assembly Lymphoid Myeloid Leukemia (CALM) Protein: Localization in Endocytic-coated Pits, Interactions with Clathrin, and the Impact of Overexpression on Clathrin-mediated Traffic

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Aging of the rat olfactory bulb: Growth and atrophy of constituent layers and changes in size and number of mitral cells

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Defects in expression of genes related to synaptic vesicle traffickingin frontal cortex of Alzheimer’s disease

Yao, P. J., Zhu, M., Pyun, E. I., Brooks, A. I., Therianos, S., Meyers, V. E., & Coleman, P. D. (2003) · Neurobiology of Disease · doi:10.1016/s0969-9961(02)00009-8 · Cited by 205 · see citing works

Morphometric and dendritic analysis of fascia dentata granule cells in human aging and senile dementia

de Ruiter, J. P., & Uylings, H. B. M. (1987) · Brain Research · doi:10.1016/0006-8993(87)90028-x · Cited by 141 · see citing works

The postsynaptic density

Kennedy, M. B. (1993) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(93)90145-o · Cited by 136 · see citing works

Quantitative Decrease in Synaptophysin Message Expression and Increase in Cathepsin D Message Expression in Alzheimer Disease Neurons Containing Neurofibrillary Tangles

Callahan, L. M., Vaules, W. A., & Coleman, P. D. (1999) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199903000-00007 · Cited by 129 · see citing works

Chapter 31 Chapter Hippocampal plasticity in normal aging and decreased plasticity in Alzheimer's disease

Flood, D. G., & Coleman, P. D. (1990) · Progress in brain research · doi:10.1016/s0079-6123(08)61267-4 · Cited by 82 · see citing works

Deterioration threshold of synaptic morphology in aging and senile dementia of Alzheimer's type.

Bertoni–Freddari, C., Fattoretti, P., Casoli, T., Caselli, U., & Meier-Ruge, W. A. (1996) · PubMed · Cited by 64 · see citing works

Progressive Reduction of Synaptophysin Message in Single Neurons in Alzheimer Disease

Callahan, L. M., Vaules, W. A., & Coleman, P. D. (2002) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/61.5.384 · Cited by 61 · see citing works

Polyadenylated Messenger RNA in Paired Helical Filament-Immunoreactive Neurons in Alzheimer Disease

Griffin, W. S. T., Ling, C., White, C. L., & Morrison‐Bogorad, M. (1990) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-199004020-00001 · Cited by 22 · see citing works

Enriched environments, experience-dependent plasticity and disorders of the nervous system

Nithianantharajah, J., & Hannan, A. J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1970 · Cited by 1,771 · see citing works

Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study

Nixon, R. A., Wegiel, J., Kumar, A., Yu, W. H., Peterhoff, C., Cataldo, A., & Cuervo, A. M. (2005) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/64.2.113 · Cited by 1,588 · see citing works

Deciphering the Molecular Basis of Memory Failure in Alzheimer's Disease

Walsh, D. M., & Selkoe, D. J. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.010 · Cited by 1,207 · see citing works

Oligomeric amyloid β associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

Koffie, R. M., Meyer-Luehmann, M., Hashimoto, T., Adams, K. W., Mielke, M. L., Garcia-Alloza, M., Micheva, K. D., Smith, S. J., Kim, M. L., Lee, V. M., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811698106 · Cited by 850 · see citing works

Biochemistry and Cell Biology of Tau Protein in Neurofibrillary DegenerationPreprint

Mandelkow, E., & Mandelkow, E. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006247 · Cited by 839 · see citing works

Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

Pun, S., Santos, A. F., Saxena, S., Xu, L., & Caroni, P. (2006) · Nature Neuroscience · doi:10.1038/nn1653 · Cited by 659 · see citing works

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Sengupta, U., Clos, A. L., Jackson, G. R., & Kayed, R. (2011) · Molecular Neurodegeneration · doi:10.1186/1750-1326-6-39 · Cited by 633 · see citing works

A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice

Saxena, S., Cabuy, E., & Caroni, P. (2009) · Nature Neuroscience · doi:10.1038/nn.2297 · Cited by 600 · see citing works

Dendritic Spine Abnormalities in Amyloid Precursor Protein Transgenic Mice Demonstrated by Gene Transfer and Intravital Multiphoton Microscopy

Spires, T. L., Meyer-Luehmann, M., Stern, E. A., McLean, P. J., Skoch, J., Nguyen, P. T., Bacskai, B. J., & Hyman, B. T. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1879-05.2005 · Cited by 550 · see citing works

Synaptic degeneration in Alzheimer's disease

Arendt, T. (2009) · Acta Neuropathologica · doi:10.1007/s00401-009-0536-x · Cited by 517 · see citing works

GSK-3β, a pivotal kinase in Alzheimer disease

Llorens-Marítin, M., Jurado, J., Hernández, F., & Ávila, J. (2014) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2014.00046 · Cited by 451 · see citing works

Amyloid toxicity in Alzheimer’s disease

Reiss, A. B., Arain, H. A., Stecker, M. M., Siegart, N. M., & Kasselman, L. J. (2018) · Reviews in the Neurosciences · doi:10.1515/revneuro-2017-0063 · Cited by 447 · see citing works

Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients

Chouliaras, L., Mastroeni, D., Delvaux, E., Grover, A., Kenis, G., Hof, P. R., Steinbusch, H. W. M., Coleman, P. D., Rutten, B. P. F., & van den Hove, D. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.02.021 · Cited by 422 · see citing works

Microtubule-associated protein tau in development, degeneration and protection of neurons

Wang, J., & Liu, F. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2008.03.002 · Cited by 395 · see citing works

Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses

Almeida, C. G., Tampellini, D., Takahashi, R. H., Greengard, P., Lin, M. T., Snyder, E. M., & Gouras, G. K. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.02.008 · Cited by 397 · see citing works

Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

Gouras, G. K., Tampellini, D., Takahashi, R. H., & Capetillo-Zarate, E. (2010) · Acta Neuropathologica · doi:10.1007/s00401-010-0679-9 · Cited by 372 · see citing works

The CAMKK2-AMPK Kinase Pathway Mediates the Synaptotoxic Effects of Aβ Oligomers through Tau Phosphorylation

Mairet-Coello, G., Courchet, J., Pieraut, S., Courchet, V., Maximov, A., & Polleux, F. (2013) · Neuron · doi:10.1016/j.neuron.2013.02.003 · Cited by 351 · see citing works

Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease

Gouras, G. K., Almeida, C. G., & Takahashi, R. H. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.05.022 · Cited by 338 · see citing works

Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets

Suthram, S., Dudley, J. T., Chiang, A. P.-F., Chen, R., Hastie, T. J., & Butte, A. J. (2010) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000662 · Cited by 323 · see citing works

Tau pathophysiology in neurodegeneration: a tangled issue

Spires‐Jones, T. L., Stoothoff, W. H., de Calignon, A., Jones, P., & Hyman, B. T. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2008.11.007 · Cited by 316 · see citing works

Alzheimer's disease: synapses gone cold

Koffie, R. M., Hyman, B. T., & Spires‐Jones, T. L. (2011) · Molecular Neurodegeneration · doi:10.1186/1750-1326-6-63 · Cited by 302 · see citing works

The Potential for β-Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy

Mocanu, M.-M., Nissen, A., Eckermann, K., Khlistunova, I., Biernat, J., Drexler, D., Petrova, O., Schönig, K., Bujard, H., Mandelkow, E., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.2824-07.2008 · Cited by 297 · see citing works

Missorting of Tau in Neurons Causes Degeneration of Synapses That Can Be Rescued by the Kinase MARK2/Par-1

Thies, E., & Mandelkow, E.-M. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.4674-06.2007 · Cited by 293 · see citing works

The amyloid cascade hypothesis: an updated critical review

Kepp, K. P., Robakis, N. K. R. K., Høilund‐Carlsen, P. F., Sensi, S. L., & Vissel, B. (2023) · Brain · doi:10.1093/brain/awad159 · Cited by 294 · see citing works

Soluble β-Amyloid1-40Induces NMDA-Dependent Degradation of Postsynaptic Density-95 at Glutamatergic Synapses

Roselli, F., Tirard, M., Lu, J., Hutzler, P., Lamberti, P., Livrea, P., Morabito, M. A., & Almeida, O. F. X. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3034-05.2005 · Cited by 276 · see citing works

Molecular mechanisms of cognitive dysfunction following traumatic brain injury

Walker, K. R., & Tesco, G. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2013.00029 · Cited by 265 · see citing works

Mechanisms of axon degeneration: From development to disease

Saxena, S., & Caroni, P. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.07.007 · Cited by 258 · see citing works

Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

Calkins, M. J., & Reddy, P. H. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2011.01.007 · Cited by 244 · see citing works

Amyloid β Oligomers (Aβ 1–42 Globulomer) Suppress Spontaneous Synaptic Activity by Inhibition of P/Q-Type Calcium Currents

Nimmrich, V., Grimm, C., Draguhn, A., Barghorn, S., Lehmann, A., Schoemaker, H., Hillen, H., Groß, G., Ebert, U., & Bruehl, C. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4771-07.2008 · Cited by 233 · see citing works

Soluble forms of tau are toxic in Alzheimer's disease

Kopeikina, K., Hyman, B., & Spires-Jones, T. (2012) · Translational Neuroscience · doi:10.2478/s13380-012-0032-y · Cited by 232 · see citing works

Down’s syndrome, neuroinflammation, and Alzheimer neuropathogenesis

Wilcock, D. M., & Griffin, W. S. T. (2013) · Journal of Neuroinflammation · doi:10.1186/1742-2094-10-84 · Cited by 230 · see citing works

Phosphorylation of tau antagonizes apoptosis by stabilizing β-catenin, a mechanism involved in Alzheimer's neurodegeneration

Li, H.-L., Wang, H.-H., Liu, S.-J., Deng, Y.-Q., Zhang, Y.-J., Tian, Q., Wang, X.-C., Chen, X., Yang, Y., Zhang, J.-Y., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609303104 · Cited by 225 · see citing works

Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration

Li, X., Kumar, Y., Zempel, H., Mandelkow, E., Biernat, J., & Mandelkow, E. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.376 · Cited by 218 · see citing works

Diagnostic and Prognostic Utility of the Synaptic Marker Neurogranin in Alzheimer Disease

Tarawneh, R. M., D’Angelo, G., Crimmins, D. L., Herries, E. M., Griest, T. A., Fagan, A. M., Zipfel, G. J., Ladenson, J. H., Morris, J. C., & Holtzman, D. M. (2016) · JAMA Neurology · doi:10.1001/jamaneurol.2016.0086 · Cited by 219 · see citing works

Caspase-3 Is Enriched in Postsynaptic Densities and Increased in Alzheimer's Disease

Louneva, N., Cohen, J. W., Han, L., Talbot, K., Wilson, R. S., Bennett, D. A., Trojanowski, J. Q., & Arnold, S. E. (2008) · American Journal Of Pathology · doi:10.2353/ajpath.2008.080434 · Cited by 207 · see citing works

Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro

Ding, B., Lin, C., Liu, Q., He, Y., Ruganzu, J. B., Jin, H., Peng, X., Ji, S., Ma, Y., & Yang, W. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01981-4 · Cited by 208 · see citing works

Acrylamide neurotoxicity

Erkekoğlu, P., & Baydar, T. (2013) · Nutritional Neuroscience · doi:10.1179/1476830513y.0000000065 · Cited by 207 · see citing works

Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimer’s disease

Liu, Y., Yoo, M.-J., Savonenko, A., Stirling, W., Price, D. L., Borchelt, D. R., Mamounas, L., Lyons, W. E., Blue, M. E., & Lee, M. K. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4218-08.2008 · Cited by 206 · see citing works

The role of cell-derived oligomers of Aβ in Alzheimer's disease and avenues for therapeutic intervention

Walsh, D. M., Klyubin, I., Shankar, G. M., Townsend, M., Fadeeva, J. V., Betts, V., Podlisny, M. B., Cleary, J. P., Ashe, K. H., Rowan, M. J., et al. (2005) · Biochemical Society Transactions · doi:10.1042/bst20051087 · Cited by 220 · see citing works

A role for tau at the synapse in Alzheimer’s disease pathogenesis

Pooler, A. M., Noble, W., & Hanger, D. P. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.09.018 · Cited by 203 · see citing works

Selective loss of cortical endothelial tight junction proteins during Alzheimer’s disease progression

Yamazaki, Y., Shinohara, M., Shinohara, M., Yamazaki, A., Murray, M. E., Liesinger, A. M., Heckman, M. G., Lesser, E. R., Parisi, J. E., Petersen, R. C., et al. (2019) · Brain · doi:10.1093/brain/awz011 · Cited by 202 · see citing works

Whole-Genome Analysis of Sporadic Amyotrophic Lateral Sclerosis

Dunckley, T., Huentelman, M. J., Craig, D. W., Pearson, J. V., Szelinger, S., Joshipura, K., Halperin, R. F., Stamper, C., Jensen, K. R., Letizia, D., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa070174 · Cited by 236 · see citing works

Impaired Spine Stability Underlies Plaque-Related Spine Loss in an Alzheimer's Disease Mouse Model

Spires-Jones, T. L., Meyer-Luehmann, M., Osetek, J. D., Jones, P. B., Stern, E. A., Bacskai, B. J., & Hyman, B. T. (2007) · The American Journal of Pathology · doi:10.2353/ajpath.2007.070055 · Cited by 189 · see citing works

Inhibition of Calcineurin-mediated Endocytosis and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors Prevents Amyloid β Oligomer-induced Synaptic Disruption

Zhao, W.-Q., Santini, F., Breese, R., Ross, D., Zhang, X. D., Stone, D. J., Ferrer, M., Townsend, M., Wolfe, A. L., Seager, M. A., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.057182 · Cited by 188 · see citing works

Down‐regulation of vesicular glutamate transporters precedes cell loss and pathology in Alzheimer's disease

Kirvell, S. L., Esiri, M. M., & Francis, P. T. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03935.x · Cited by 187 · see citing works

Oligomeric Amyloid Decreases Basal Levels of Brain-Derived Neurotrophic factor (BDNF) mRNA via Specific Downregulation of BDNF Transcripts IV and V in Differentiated Human Neuroblastoma Cells

Garzon, D. J., & Fahnestock, M. L. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.5053-06.2007 · Cited by 182 · see citing works

Molecular Mechanisms of the Conjugated α,β-Unsaturated Carbonyl Derivatives: Relevance to Neurotoxicity and Neurodegenerative Diseases

LoPachin, R. M., Barber, D. S., & Gavin, T. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm301 · Cited by 182 · see citing works

Silver nanoparticles (AgNPs) cause degeneration of cytoskeleton and disrupt synaptic machinery of cultured cortical neurons

Xu, F.-L., Piett, C., Farkas, S., Qazzaz, M., & Syed, N. (2013) · Molecular Brain · doi:10.1186/1756-6606-6-29 · Cited by 176 · see citing works

Calcium dysregulation in Alzheimer's disease: From mechanisms to therapeutic opportunities

Yu, J., Chang, R. C., & Tan, L. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.07.009 · Cited by 168 · see citing works

The β-Propensity of Tau Determines Aggregation and Synaptic Loss in Inducible Mouse Models of Tauopathy

Eckermann, K., Mocanu, M.-M., Khlistunova, I., Biernat, J., Nissen, A., Hofmann, A., Schönig, K., Bujard, H., Haemisch, A., Mandelkow, E., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m705282200 · Cited by 168 · see citing works

The intersection of amyloid beta and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease

Crimins, J. L., Pooler, A. M., Polydoro, M., Luebke, J. I., & Spires‐Jones, T. L. (2013) · Ageing Research Reviews · doi:10.1016/j.arr.2013.03.002 · Cited by 161 · see citing works

Cortical tau load is associated with white matter hyperintensities

McAleese, K. E., Firbank, M., Dey, M., Colloby, S. J., Walker, L., Johnson, M., Beverley, J. R., Taylor, J. P., Thomas, A. J., O’Brien, J. T., et al. (2015) · Acta Neuropathologica Communications · doi:10.1186/s40478-015-0240-0 · Cited by 161 · see citing works

Soluble hyper-phosphorylated tau causes microtubule breakdown and functionally compromises normal tau in vivo

Cowan, C. M., Bossing, T., Page, A., Shepherd, D., & Mudher, A. (2010) · Acta Neuropathologica · doi:10.1007/s00401-010-0716-8 · Cited by 156 · see citing works

Co-occurrence of Alzheimer's disease β-amyloid and tau pathologies at synapses

Takahashi, R. H., Capetillo-Zarate, E., Lin, M. T., Milner, T. A., & Gouras, G. K. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.07.021 · Cited by 150 · see citing works

Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model

Castillo-Carranza, D. L., Guerrero-Muñoz, M. J., Sengupta, U., Hernandez, C., Barrett, A. D. T., Dineley, K., & Kayed, R. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.4989-14.2015 · Cited by 149 · see citing works

Neuronal death: where does the end begin?

Conforti, L., Adalbert, R., & Coleman, M. P. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.02.004 · Cited by 148 · see citing works

Is aging part of Alzheimer's disease, or is Alzheimer's disease part of aging?

Swerdlow, R. H. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.06.021 · Cited by 144 · see citing works

CREB expression mediates amyloid β-induced basal BDNF downregulation

Rosa, E., & Fahnestock, M. (2015) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.04.014 · Cited by 138 · see citing works

Stabilizing ER Ca2+ Channel Function as an Early Preventative Strategy for Alzheimer’s Disease

Chakroborty, S., Briggs, C. A., Miller, M. B., Goussakov, I. V., Schneider, C., Kim, J. S., Wicks, J. M., Richardson, J. C., Conklin, V., Cameransi, B. G., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052056 · Cited by 136 · see citing works

Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer’s brains

Ando, K., Brion, J.-P., Stygelbout, V., Suain, V., Authelet, M., Dedecker, R., Chanut, A., Lacor, P., Lavaur, J., Sazdovitch, V., et al. (2013) · Acta Neuropathologica · doi:10.1007/s00401-013-1111-z · Cited by 136 · see citing works

Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau

Van der Jeugd, A., Hochgräfe, K., Ahmed, T., Decker, J. M., Sydow, A., Hofmann, A., Wu, D., Messing, L., Balschun, D., D’Hooge, R., et al. (2012) · Acta Neuropathologica · doi:10.1007/s00401-012-0987-3 · Cited by 135 · see citing works

The behavioral, pathological and therapeutic features of the senescence-accelerated mouse prone 8 strain as an Alzheimer's disease animal model

Cheng, X., Zhou, W., & Zhang, Y. (2013) · Ageing Research Reviews · doi:10.1016/j.arr.2013.10.002 · Cited by 133 · see citing works

Spines, plasticity, and cognition in Alzheimer's model mice

Spires-Jones, T., & Knafo, S. (2012) · Neural Plasticity · doi:10.1155/2012/319836 · Cited by 133 · see citing works

Synaptic dysfunction and septin protein family members in neurodegenerative diseases

Marttinen, M., Kurkinen, K. M. A., Soininen, H. S., Haapasalo, A., & Hiltunen, M. O. (2015) · Molecular Neurodegeneration · doi:10.1186/s13024-015-0013-z · Cited by 129 · see citing works

Late onset Alzheimer’s disease in older people

Işık, A. T. (2010) · Clinical Interventions in Aging · doi:10.2147/cia.s11718 · Cited by 129 · see citing works

Synaptic Activity Reduces Intraneuronal Aβ, Promotes APP Transport to Synapses, and Protects against Aβ-Related Synaptic Alterations

Tampellini, D., Rahman, N., Gallo, E. F., Huang, Z., Dumont, M., Capetillo-Zarate, E., Ma, T., Zheng, R., Lu, B., Nanus, D. M., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.2292-09.2009 · Cited by 127 · see citing works

-Amyloid Disrupts Activity-Dependent Gene Transcription Required for Memory through the CREB Coactivator CRTC1

España, J., Valero, J., Miñano-Molina, A. J., Masgrau, R., Martín, E., Guardia‐Laguarta, C., Lleó, A., Giménez‐Llort, L., Rodrı́guez-Álvarez, J., & Saura, C. A. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.2154-10.2010 · Cited by 127 · see citing works

Synaptic alterations in the rTg4510 mouse model of tauopathy

Kopeikina, K. J., Polydoro, M., Tai, H., Yaeger, E., Carlson, G. A., Pitstick, R., Hyman, B. T., & Spires‐Jones, T. L. (2012) · The Journal of Comparative Neurology · doi:10.1002/cne.23234 · Cited by 125 · see citing works

Synaptic Cysteine Sulfhydryl Groups as Targets of Electrophilic Neurotoxicants

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Alzheimer’s disease due to loss of function: A new synthesis of the available data

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Staying Connected

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