Co-occurrence of Alzheimer's disease β-amyloid and tau pathologies at synapses

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F., & Cole, G. (1996) · Science · doi:10.1126/science.274.5284.99 · Cited by 4,210 · see citing works

Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles

Oddo, S., Caccamo, A., Shepherd, J. D., Murphy, M. P., Golde, T. E., Kayed, R., Metherate, R., Mattson, M. P., Akbari, Y., & LaFerla, F. M. (2003) · Neuron · doi:10.1016/s0896-6273(03)00434-3 · Cited by 4,126 · see citing works

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Oakley, H., Cole, S. L., Logan, S., Maus, E., Shao, P., Craft, J., Guillozet-Bongaarts, A., Ohno, M., Disterhoft, J., Van Eldik, L., et al. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1202-06.2006 · Cited by 3,530 · cited 2× · see citing works

Intracellular amyloid-β in Alzheimer's disease

LaFerla, F. M., Green, K. N., & Oddo, S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2168 · Cited by 1,942 · see citing works

Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model

Roberson, E. D., Scearce-Levie, K., Palop, J. J., Yan, F., Cheng, I. H., Wu, T., Gerstein, H., Yu, G.-Q., & Mucke, L. (2007) · Science · doi:10.1126/science.1141736 · Cited by 1,892 · see citing works

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP

Lewis, J., Dickson, D. W., Lin, W.-L., Chisholm, L., Corral, A., Jones, G., Yen, S.-H., Sahara, N., Skipper, L., Yager, D., et al. (2001) · Science · doi:10.1126/science.1058189 · Cited by 1,611 · see citing works

Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils

Götz, J., Chen, F., van Dorpe, J., & Nitsch, R. M. (2001) · Science · doi:10.1126/science.1062097 · Cited by 1,526 · see citing works

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

Sturchler-Pierrat, C., Abramowski, D., Duke, M., Wiederhold, K.-H., Mistl, C., Rothacher, S., Ledermann, B., Bürki, K., Frey, P., Paganetti, P. A., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.13287 · Cited by 1,507 · see citing works

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

Holcomb, L., Gordon, M. N., McGowan, E., Yu, X., Benkovic, S., Jantzen, P., Wright, K., Saad, I., Mueller, R., Morgan, D., et al. (1998) · Nature Medicine · doi:10.1038/nm0198-097 · Cited by 1,386 · see citing works

Intraneuronal Aβ Causes the Onset of Early Alzheimer’s Disease-Related Cognitive Deficits in Transgenic Mice

Billings, L. M., Oddo, S., Green, K. N., McGaugh, J. L., & LaFerla, F. M. (2005) · Neuron · doi:10.1016/j.neuron.2005.01.040 · Cited by 1,294 · see citing works

Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer’s Disease

Stokin, G. B., Lillo, C., Falzone, T. L., Brusch, R. G., Rockenstein, E., Mount, S. L., Raman, R., Davies, P., Masliah, E., Williams, D. S., et al. (2005) · Science · doi:10.1126/science.1105681 · Cited by 1,214 · see citing works

Intraneuronal Aβ42 Accumulation in Human Brain

Gouras, G. K., Tsai, J., Naslund, J., Vincent, B., Edgar, M., Checler, F., Greenfield, J. P., Haroutunian, V., Buxbaum, J. D., Xu, H., et al. (2000) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64700-1 · Cited by 991 · see citing works

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice

Chapman, P. F., White, G. L., Jones, M. W., Cooper-Blacketer, D., Marshall, V. J., Irizarry, M., Younkin, L., Good, M. A., Bliss, T. V. P., Hyman, B. T., et al. (1999) · Nature Neuroscience · doi:10.1038/6374 · Cited by 946 · see citing works

Aβ Immunotherapy Leads to Clearance of Early, but Not Late, Hyperphosphorylated Tau Aggregates via the Proteasome

Oddo, S., Billings, L., Kesslak, J. P., Cribbs, D. H., & LaFerla, F. M. (2004) · Neuron · doi:10.1016/j.neuron.2004.07.003 · Cited by 780 · see citing works

Intraneuronal Alzheimer Aβ42 Accumulates in Multivesicular Bodies and Is Associated with Synaptic Pathology

Takahashi, R. H., Milner, T. A., Li, F., Nam, E. E., Edgar, M. A., Yamaguchi, H., Beal, M. F., Xu, H., Greengard, P., & Gouras, G. K. (2002) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64463-x · Cited by 706 · see citing works

β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

Zheng, H., Jiang, M., Trumbauer, M. E., SIRINATHSINGHJI, D. J. S., Hopkins, R., Smith, D. W., HEAVENS, R. P., Dawson, G. R., Boyce, S., Conner, M. W., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90073-x · Cited by 699 · see citing works

Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain

Moechars, D., Dewachter, I., Lorent, K., Reversé, D., Baekelandt, V., Naidu, A., Tesseur, I., Spittaels, K., Haute, C. V. D., Checler, F., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.10.6483 · Cited by 668 · see citing works

Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP

Kamal, A., Almenar-Queralt, A., LeBlanc, J. F., Roberts, E. A., & Goldstein, L. S. B. (2001) · Nature · doi:10.1038/414643a · Cited by 583 · see citing works

Oligomerization of Alzheimer's β-Amyloid within Processes and Synapses of Cultured Neurons and Brain

Takahashi, R. H., Almeida, C. G., Kearney, P. F., Yu, F., Lin, M. T., Milner, T. A., & Gouras, G. K. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.5167-03.2004 · Cited by 445 · see citing works

Alzheimer disease models and human neuropathology: similarities and differences

Duyckaerts, C. J., Potier, M., & Delatour, B. (2007) · Acta Neuropathologica · doi:10.1007/s00401-007-0312-8 · Cited by 441 · see citing works

Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer’s disease

D'Andrea, M. R., Nagele, R. G., Wang, H., Peterson, P. A., & Lee, D. H. S. (2001) · Histopathology · doi:10.1046/j.1365-2559.2001.01082.x · Cited by 390 · see citing works

Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid β peptide in APPswe transgenic mice

Sheng, J. (2003) · Neurobiology of Disease · doi:10.1016/s0969-9961(03)00069-x · Cited by 388 · see citing works

Altered Metabolism of the Amyloid β Precursor Protein Is Associated with Mitochondrial Dysfunction in Down's Syndrome

Busciglio, J., Pelsman, A., Wong, C., Pigino, G., Yuan, M., Mori, H., & Yankner, B. A. (2002) · Neuron · doi:10.1016/s0896-6273(02)00604-9 · Cited by 387 · see citing works

Aβ localization in abnormal endosomes: association with earliest Aβ elevations in AD and Down syndrome

Cataldo, A. M., Petanceska, S., Terio, N. B., Peterhoff, C. M., Durham, R., Mercken, M., Mehta, P. D., Buxbaum, J., Haroutunian, V., & Nixon, R. A. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.02.027 · Cited by 363 · see citing works

Synaptic slaughter in Alzheimer's disease

Coleman, P. (2003) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2003.09.001 · Cited by 351 · see citing works

Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease

Gouras, G. K., Almeida, C. G., & Takahashi, R. H. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.05.022 · Cited by 338 · see citing works

Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice

Wirths, O., Multhaup, G., Czech, C., Blanchard, V., Moussaoui, S., Tremp, G., Pradier, L., Beyreuther, K., & Bayer, T. A. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)01876-6 · Cited by 336 · see citing works

β-Amyloid Accumulation Impairs Multivesicular Body Sorting by Inhibiting the Ubiquitin-Proteasome System

Almeida, C. G., Takahashi, R. H., & Gouras, G. K. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.5078-05.2006 · Cited by 316 · see citing works

Intracellular Aβ42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease

Ohyagi, Y., Asahara, H., Chui, D.-H., Tsuruta, Y., Sakae, N., Miyoshi, K., Yamada, T., Kikuchi, H., Taniwaki, T., Murai, H., et al. (2005) · The FASEB Journal · doi:10.1096/fj.04-2637fje · Cited by 281 · see citing works

A Conformation‐ and Phosphorylation‐Dependent Antibody Recognizing the Paired Helical Filaments of Alzheimer's Disease

Jicha, G. A., Lane, E., Vincent, I. J., Ötvös, L., Hoffmann, R., & Davies, P. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69052087.x · Cited by 264 · see citing works

The Arctic Alzheimer mutation facilitates early intraneuronal Aβ aggregation and senile plaque formation in transgenic mice

Lord, A., Kalimo, H., Eckman, C., Zhang, X.-Q., Lannfelt, L., & Nilsson, L. N. G. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.12.007 · Cited by 260 · see citing works

Intracellular Aβ and cognitive deficits precede β-amyloid deposition in transgenic arcAβ mice

Knobloch, M., Konietzko, U., Krebs, D. C., & Nitsch, R. M. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.06.019 · Cited by 259 · see citing works

Intraneuronal Aβ42 accumulation in Down syndrome brain: Original Articles

Mori, C., Spooner, E. T., Wisniewski, K. E., Wisniewski, T. M., Yamaguchi, H., Saido, T. C., Tolan, D. R., Selkoe, D. J., & Lemere, C. A. (2002) · Amyloid · doi:10.3109/13506120208995241 · Cited by 255 · see citing works

Intraneuronal Aβ-Amyloid Precedes Development of Amyloid Plaques in Down Syndrome

Gyure, K. A., Durham, R., Stewart, W. F., Smialek, J. E., & Troncoso, J. C. (2001) · Archives of Pathology & Laboratory Medicine · doi:10.5858/2001-125-0489-iaapdo · Cited by 248 · see citing works

Intracellular Mechanisms of Amyloid Accumulation and Pathogenesis in Alzheimer's Disease

Glabe, C. (2001) · Journal of Molecular Neuroscience · doi:10.1385/jmn:17:2:137 · Cited by 222 · see citing works

p25/Cyclin-Dependent Kinase 5 Induces Production and Intraneuronal Accumulation of Amyloid βIn Vivo

Cruz, J. C., Kim, D., Moy, L. Y., Dobbin, M. M., Sun, X., Bronson, R. T., & Tsai, L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3133-06.2006 · Cited by 197 · see citing works

Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356

Litersky, J. M., Johnson, G. V. W., Jakes, R., Goedert, M., Lee, M., & Seubert, P. A. (1996) · Biochemical Journal · doi:10.1042/bj3160655 · Cited by 150 · see citing works

Apolipoprotein E and Low Density Lipoprotein Receptor-related Protein Facilitate Intraneuronal Aβ42 Accumulation in Amyloid Model Mice

Zerbinatti, C. V., Wahrle, S. E., Kim, H., Cam, J. A., Bales, K., Paul, S. M., Holtzman, D. M., & Bu, G. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m604436200 · Cited by 129 · see citing works

AβPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576

Carola Otth, L., Concha, I. I., Arendt, T., Stieler, J., Schliebs, R., González-Billault, C. E., & Maccioni, R. B. (2002) · Journal of Alzheimer s Disease · doi:10.3233/jad-2002-4508 · Cited by 119 · see citing works

Hippocampal alpha2a-adrenergic receptors are located predominantly presynaptically but are also found postsynaptically and in selective astrocytes.

Milner, T. A., Lee, A., Aicher, S. A., & Rosin, D. L. (1998) · PubMed · Cited by 107 · see citing works

Inter-laboratory comparison of neuropathological assessments of β-amyloid protein: a study of the BrainNet Europe consortium

Alafuzoff, I. I., Pikkarainen, M., Arzberger, T., Thal, D. R., Al‐Sarraj, S., Bell, J. E., Bódi, I., Budka, H., Capetillo‐Zarate, E., Ferrer, I., et al. (2008) · Acta Neuropathologica · doi:10.1007/s00401-008-0358-2 · Cited by 105 · see citing works

Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the β-amyloid peptide intracellularly in hippocampal and cortical neurons

Echeverrı́a, V., Ducatenzeiler, A., Dowd, E., Jänne, J., Grant, S. M., Szyf, M., Wandosell, F. G., Ávila, J., Grimm, H. S., Dunnett, S. B., et al. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.07.036 · Cited by 101 · see citing works

Early intraneuronal Aβ deposition in the hippocampus of APP transgenic mice

Shie, F., LeBoeur, R. C., & Jin, L. (2003) · Neuroreport · doi:10.1097/00001756-200301200-00023 · Cited by 83 · see citing works

Intraneuronal amyloid β and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease

Van Broeck, B., Vanhoutte, G., Pirici, D., Van Dam, D., Wils, H., Cuijt, I., Vennekens, K., Zabielski, M., Michalik, A., Theuns, J., et al. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.10.016 · Cited by 60 · see citing works

Review on the APP/PS1KI mouse model: intraneuronal Aβ accumulation triggers axonopathy, neuron loss and working memory impairment

Bayer, T. A., & Wirths, O. (2008) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2007.00372.x · Cited by 60 · see citing works

Untitled work

(1998) · doi:10.1002/(sici)1096-9861(19980808)395:3

Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease.

(2015) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.2305-5839.2015.03.49 · Cited by 1,288 · see citing works

Basic mechanisms of neurodegeneration: a critical update

Jellinger, K. A. (2010) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2010.01010.x · Cited by 608 · see citing works

Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease

Tu, S., Okamoto, S., Lipton, S. A., & Xu, H. (2014) · Molecular Neurodegeneration · doi:10.1186/1750-1326-9-48 · Cited by 582 · see citing works

Synaptic degeneration in Alzheimer's disease

Arendt, T. (2009) · Acta Neuropathologica · doi:10.1007/s00401-009-0536-x · Cited by 517 · see citing works

Reduced IGF-1 signaling delays age-associated proteotoxicity in mice

Cohen, E., Paulsson, J. F., Blinder, P., Burstyn-Cohen, T., Du, D., Estepa, G., Adame, A., Pham, H. M., Holzenberger, M., Kelly, J. W., et al. (2009) · Cell · doi:10.1016/j.cell.2009.11.014 · Cited by 488 · see citing works

Interactions of pathological proteins in neurodegenerative diseases

Spires‐Jones, T. L., Attems, J., & Thal, D. R. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1709-7 · Cited by 424 · see citing works

Alzheimer's disease: connecting findings from graph theoretical studies of brain networks

Tijms, B. M., Wink, A. M., de Haan, W., van der Flier, W. M., Stam, C. J., Scheltens, P., & Barkhof, F. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.02.020 · Cited by 416 · see citing works

Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction

Mietelska‐Porowska, A., Wasik, U., Goras, M., Filipek, A., & Niewiadomska, G. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15034671 · Cited by 407 · see citing works

Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits

Majumder, S., Richardson, A. G., Strong, R., & Oddo, S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025416 · Cited by 401 · see citing works

Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

Gouras, G. K., Tampellini, D., Takahashi, R. H., & Capetillo-Zarate, E. (2010) · Acta Neuropathologica · doi:10.1007/s00401-010-0679-9 · Cited by 372 · see citing works

Plaque formation and the intraneuronal accumulation of β‐amyloid in Alzheimer's disease

Takahashi, R. H., Nagao, T., & Gouras, G. K. (2017) · Pathology International · doi:10.1111/pin.12520 · Cited by 354 · see citing works

Microglia receptors and their implications in the response to amyloid β for Alzheimer’s disease pathogenesis

Doens, D., & Fernández, P. L. (2014) · Journal of Neuroinflammation · doi:10.1186/1742-2094-11-48 · Cited by 348 · see citing works

Neuropathology and biochemistry of Aβ and its aggregates in Alzheimer’s disease

Thal, D. R., Walter, J., Saido, T. C., & Fändrich, M. (2015) · Acta Neuropathologica · doi:10.1007/s00401-014-1375-y · Cited by 319 · see citing works

Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials

Weiner, M. W., Veitch, D. P., Aisen, P. S. S., Beckett, L. A., Cairns, N. J., Green, R. C., Harvey, D. J., Jack, C. R., Jagust, W. J., Morris, J. C., et al. (2017) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2016.11.007 · Cited by 314 · see citing works

Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease

Reddy, P. H. (2011) · Brain Research · doi:10.1016/j.brainres.2011.07.052 · Cited by 300 · see citing works

Recent advances in our understanding of neurodegeneration

Jellinger, K. A. (2009) · Journal of Neural Transmission · doi:10.1007/s00702-009-0240-y · Cited by 274 · see citing works

Memantine for the Treatment of Dementia: A Review on its Current and Future Applications

Folch, J., Busquets, O., Ettcheto, M., Sánchez-López, E., Castro-Torres, R. D., Verdaguer, E., Garcia, M. L., Olloquequi, J., Casadesús, G., Beas-Zarate, C., et al. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-170672 · Cited by 245 · see citing works

Analyzing dendritic spine pathology in Alzheimer’s disease: Problems and opportunities

Dorostkar, M. M., Zou, C., Blazquez-Llorca, L., & Herms, J. (2015) · Acta Neuropathologica · doi:10.1007/s00401-015-1449-5 · Cited by 235 · see citing works

Dendritic Spine Pathology in Neurodegenerative Diseases

Herms, J., & Dorostkar, M. M. (2016) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-012615-044216 · Cited by 201 · see citing works

Fluid Biomarkers for Synaptic Dysfunction and Loss

Camporesi, E., Nilsson, J., Brinkmalm, A., Becker, B., Ashton, N. J., Blennow, K., & Zetterberg, H. (2020) · Biomarker Insights · doi:10.1177/1177271920950319 · Cited by 165 · see citing works

Synaptic Change in the Posterior Cingulate Gyrus in the Progression of Alzheimer's Disease

Scheff, S. W., PRICE, D. A., Ansari, M. A., Roberts, K. N., Schmitt, F. A., Ikonomović, M. D., & Mufson, E. J. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-141518 · Cited by 163 · see citing works

Selective impairment of hippocampus and posterior hub areas in Alzheimer’s disease: an MEG-based multiplex network study

Yu, M., Engels, M. M. A., Hillebrand, A., van Straaten, E. C. W., Gouw, A. A., Teunissen, C. E., van der Flier, W. M., Scheltens, P., & Stam, C. J. (2017) · Brain · doi:10.1093/brain/awx050 · Cited by 157 · see citing works

Effects of Synaptic Modulation on β-Amyloid, Synaptophysin, and Memory Performance in Alzheimer's Disease Transgenic Mice

Tampellini, D., Capetillo‐Zarate, E., Dumont, M., Huang, Z., Yu, F., Lin, M. T. S., & Gouras, G. K. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3383-10.2010 · Cited by 161 · see citing works

The synapse as a treatment avenue for Alzheimer’s Disease

Peng, L., Bestard‐Lorigados, I., & Song, W. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01565-z · Cited by 158 · see citing works

The lysosome and neurodegenerative diseases

Zhang, L., Sheng, R., & Qin, Z. (2009) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmp031 · Cited by 152 · see citing works

Pathophysiology of neuropathic lysosomal storage disorders

Bellettato, C. M., & Scarpa, M. (2010) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-010-9075-9 · Cited by 141 · see citing works

Single-Subject Grey Matter Graphs in Alzheimer's Disease

Tijms, B. M., Möller, C., Vrenken, H., Wink, A. M., de Haan, W., van der Flier, W. M., Stam, C. J., Scheltens, P., & Barkhof, F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058921 · Cited by 132 · see citing works

Interaction between pathogenic proteins in neurodegenerative disorders

Jellinger, K. A. (2011) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2011.01507.x · Cited by 128 · see citing works

Synaptic Activity Reduces Intraneuronal Aβ, Promotes APP Transport to Synapses, and Protects against Aβ-Related Synaptic Alterations

Tampellini, D., Rahman, N., Gallo, E. F., Huang, Z., Dumont, M., Capetillo-Zarate, E., Ma, T., Zheng, R., Lu, B., Nanus, D. M., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.2292-09.2009 · Cited by 127 · see citing works

Intracellular Accumulation of Amyloid- (A ) Protein Plays a Major Role in A -Induced Alterations of Glutamatergic Synaptic Transmission and Plasticity

Ripoli, C., Cocco, S., Puma, D. D. L., Piacentini, R., Mastrodonato, A., Scala, F., Puzzo, D., D’Ascenzo, M., & Grassi, C. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1201-14.2014 · Cited by 122 · see citing works

Synaptic Dysfunction in Alzheimer’s Disease: Aβ, Tau, and Epigenetic Alterations

Li, K., Wei, Q., Liu, F., Hu, F., Xie, A., Zhu, L., & Liu, D. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0533-3 · Cited by 119 · see citing works

Synaptic Elimination in Neurological Disorders

Cardozo, P. L., de Lima, I. B. Q., Maciel, E. M. A., Silva, N. C., Dobránsky, T., & Ribeiro, F. M. (2019) · Current Neuropharmacology · doi:10.2174/1570159x17666190603170511 · Cited by 113 · see citing works

Roles of Microglial and Monocyte Chemokines and Their Receptors in Regulating Alzheimer's Disease-Associated Amyloid-β and Tau Pathologies

Guedes, J. R., Lao, T., Cardoso, A. L., & El Khoury, J. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00549 · Cited by 115 · see citing works

Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases

Bilousova, T. V., Miller, C. A., Poon, W. W., Vinters, H. V., Corrada, M. M., Kawas, C. H., Hayden, E. Y., Teplow, D. B., Glabe, C. G., Albay, R., et al. (2015) · American Journal Of Pathology · doi:10.1016/j.ajpath.2015.09.018 · Cited by 112 · see citing works

Capillary cerebral amyloid angiopathy identifies a distinct APOE ε4-associated subtype of sporadic Alzheimer’s disease

Thal, D. R., Papassotiropoulos, A., Saido, T. C., Griffin, W. S. T., Mrak, R. E., Kölsch, H., Tredici, K. D., Attems, J., & Ghebremedhin, E. (2010) · Acta Neuropathologica · doi:10.1007/s00401-010-0707-9 · Cited by 103 · see citing works

Oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with Alzheimer’s disease pathology

Scheff, S. W., Ansari, M. A., & Mufson, E. J. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2016.02.030 · Cited by 100 · see citing works

Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K+ current inhibition mediated by activation of caspases and GSK-3

Scala, F., Fusco, S., Ripoli, C., Piacentini, R., Puma, D. D. L., Spinelli, M., Laezza, F., Grassi, C., & D’Ascenzo, M. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.10.034 · Cited by 96 · see citing works

Kv1.3 Channel as a Key Therapeutic Target for Neuroinflammatory Diseases: State of the Art and Beyond

Wang, X., Li, G., Guo, J., Zhang, Z., Zhang, S., Zhu, Y., Cheng, J., Yu, L., Ji, Y., & Tao, J. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01393 · Cited by 93 · see citing works

Interaction between NH2-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deterioration

Amadoro, G., Corsetti, V., Atlante, A., Florenzano, F., Capsoni, S., Bussani, R., Mercanti, D., & Calissano, P. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.08.001 · Cited by 94 · see citing works

Degenerating Processes Identified by Electron Microscopic Immunocytochemical Methods

Milner, T. A., Waters, E. M., Robinson, D. C., & Pierce, J. P. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-328-8_3 · Cited by 93 · see citing works

Blocking the Interaction between Apolipoprotein E and Aβ Reduces Intraneuronal Accumulation of Aβ and Inhibits Synaptic Degeneration

Kuszczyk, M. A., Sanchez, S., Pankiewicz, J., Kim, J., Duszczyk, M., Guridi, M., Asuni, A. A., Sullivan, P. M., Holtzman, D. M., & Sadowski, M. J. (2013) · The American Journal of Pathology · doi:10.1016/j.ajpath.2013.01.034 · Cited by 89 · see citing works

Graph theoretic analysis of structural connectivity across the spectrum of Alzheimer's disease: The importance of graph creation methods

Phillips, D. J., McGlaughlin, A., Ruth, D. M., Jager, L. R., & Soldan, A. (2015) · NeuroImage Clinical · doi:10.1016/j.nicl.2015.01.007 · Cited by 89 · see citing works

Optical visualization of Alzheimer’s pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation

Kwan, A. C., Duff, K., Gouras, G. K., & Webb, W. W. (2009) · Optics Express · doi:10.1364/oe.17.003679 · Cited by 89 · see citing works

Abnormal Interaction of Oligomeric Amyloid-β with Phosphorylated Tau: Implications to Synaptic Dysfunction and Neuronal Damage

Mańczak, M., & Reddy, P. H. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-130275 · Cited by 88 · see citing works

The Impact of Surgery and Anesthesia on Post-Operative Cognitive Decline and Alzheimer's Disease Development: Biomarkers and Preventive Strategies

Kapila, A. K., Watts, H. R., Wang, T., & Ma, D. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-132258 · Cited by 86 · see citing works

Neuropathological assessment of the Alzheimer spectrum

Jellinger, K. A. (2020) · Journal of Neural Transmission · doi:10.1007/s00702-020-02232-9 · Cited by 82 · see citing works

Neuroprotection by IFN-γviaastrocyte-secreted IL-6 in acute neuroinflammation

Sun, L., Li, Y., Jia, X., Wang, Q., Li, Y., Hu, M., Tian, L., Yang, J., Xing, W., Zhang, W., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.16990 · Cited by 73 · see citing works

Extensive p‐Tau Pathology and SDS‐Stable p‐Tau Oligomers in Alzheimer's Cortical Synapses

Henkins, K. M., Sokolow, S., Miller, C. A., Vinters, H. V., Poon, W. W., Cornwell, L. B., Saing, T., & Gylys, K. H. (2012) · Brain Pathology · doi:10.1111/j.1750-3639.2012.00598.x · Cited by 70 · see citing works

Alzheimer’s Disease: A Clinical Practice-Oriented Review

Alves, L., Correia, A. S., Miguel, R., Alegria, P., & Bugalho, P. (2012) · Frontiers in Neurology · doi:10.3389/fneur.2012.00063 · Cited by 69 · see citing works

Interaction between -Synuclein and Other Proteins in Neurodegenerative Disorders

Jellinger, K. A. (2011) · The Scientific World JOURNAL · doi:10.1100/2011/371893 · Cited by 63 · see citing works

Activation of PPARα enhances astroglial uptake and degradation of β-amyloid

Raha, S., Ghosh, A., Dutta, D., Patel, D. R., & Pahan, K. (2021) · Science Signaling · doi:10.1126/scisignal.abg4747 · Cited by 63 · see citing works

Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice

Hoffmann, N. A., Dorostkar, M. M., Blumenstock, S., Goedert, M., & Herms, J. W. (2013) · Acta Neuropathologica Communications · doi:10.1186/2051-5960-1-82 · Cited by 64 · see citing works

Cellular factors modulating the mechanism of tau protein aggregation

Fontaine, S. N., Sabbagh, J. J., Baker, J. D., Licha, C. R. M., Darling, A. L., & Dickey, C. A. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-1839-9 · Cited by 60 · see citing works

Accumulation of Intraneuronal β-Amyloid 42 Peptides Is Associated with Early Changes in Microtubule-Associated Protein 2 in Neurites and Synapses

Takahashi, R. H., Capetillo‐Zarate, E., Lin, M. T. S., Milner, T. A., & Gouras, G. K. (2013) · PLoS ONE · doi:10.1371/journal.pone.0051965 · Cited by 60 · see citing works

Emerging Proof of Protein Misfolding and Interactions in Multifactorial Alzheimer's Disease

Uddin, M. S., Mamun, A. A., Rahman, M. A., Behl, T., Perveen, A., Hafeez, A., Bin-Jumah, M. N., Abdel‐Daim, M. M., & Ashraf, G. M. (2020) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026620666200601161703 · Cited by 59 · see citing works

Codonopsis pilosula polysaccharide attenuates Aβ toxicity and cognitive defects in APP/PS1 mice

Wan, L., Zhang, Q., Luo, H., Xu, Z., Huang, S., Yang, F., Liu, Y., Mahaman, Y. A. R., Ke, D., Wang, Q., et al. (2020) · Aging · doi:10.18632/aging.103445 · Cited by 59 · see citing works

The γ-Secretase Modulator CHF5074 Restores Memory and Hippocampal Synaptic Plasticity in Plaque-Free Tg2576 Mice

Balducci, C., Mehdawy, B., Mare, L., Giuliani, A., Lorenzini, L., Sivilia, S., Giardino, L., Calzà, L., Lanzillotta, A., Sarnico, I., et al. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-101839 · Cited by 58 · see citing works

AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly

Sokolow, S., Henkins, K. M., Bilousova, T. V., Miller, C. A., Vinters, H. V., Poon, W. W., Cole, G. M., & Gylys, K. H. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.05.011 · Cited by 57 · see citing works

Synapses, synaptic activity and intraneuronal Aβ in Alzheimer’s disease

Tampellini, D. (2010) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2010.00013 · Cited by 54 · see citing works

Novel 3-phenylcoumarin–lipoic acid conjugates as multi-functional agents for potential treatment of Alzheimer's disease

Jalili‐Baleh, L., Nadri, H., Forootanfar, H., Samzadeh‐Kermani, A., Küçükkılınç, T. T., Ayazgök, B., Rahimifard, M., Baeeri, M., Doostmohammadi, M., Firoozpour, L., et al. (2018) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2018.04.030 · Cited by 53 · see citing works

Brain Connectivity and Graph Theory Analysis in Alzheimer’s and Parkinson’s Disease: The Contribution of Electrophysiological Techniques

Miraglia, F., Vecchio, F., Pappalettera, C., Nucci, L., Cotelli, M., Judica, E., Ferreri, F., & Rossini, P. M. (2022) · Brain Sciences · doi:10.3390/brainsci12030402 · Cited by 46 · see citing works

Development of new fusion proteins for visualizing amyloid-β oligomers in vivo

Ochiishi, T., Doi, M., Yamasaki, K., Hirose, K., Kitamura, A., Urabe, T., Hattori, N., Kinjo, M., Ebihara, T., & Shimura, H. (2016) · Scientific Reports · doi:10.1038/srep22712 · Cited by 46 · see citing works

Memory Deficits in Aging and Neurological Diseases

Khan, Z. U., Martín‐Montañez, E., Navarro‐Lobato, I., & Muly, E. C. (2014) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-420170-5.00001-5 · Cited by 46 · see citing works

Defining and predicting transdiagnostic categories of neurodegenerative disease

Cornblath, E. J., Robinson, J. L., Irwin, D. J., Lee, E. B., Lee, V. M. ‐., Trojanowski, J. Q., & Bassett, D. S. (2020) · Nature Biomedical Engineering · doi:10.1038/s41551-020-0593-y · Cited by 44 · see citing works

Neuropathology of the Alzheimer's continuum: an update

Jellinger, K. A. (2020) · Free Neuropathology · doi:10.17879/freeneuropathology-2020-3050 · Cited by 45 · see citing works

Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer’s disease models

Corsetti, V., Borreca, A., Latina, V., Giacovazzo, G., Pignataro, A., Krashia, P., Natale, F., Cocco, S., Rinaudo, M., Malerba, F., et al. (2020) · Brain Communications · doi:10.1093/braincomms/fcaa039 · Cited by 41 · see citing works

Alzheimer’s Disease and Protein Kinases

Engin, A. B., & Engin, A. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-49844-3_11 · Cited by 42 · see citing works

The Inside-Out Amyloid Hypothesis and Synapse Pathology in Alzheimer's Disease

Gouras, G. K., Willén, K. I., & Faideau, M. (2013) · Neurodegenerative Diseases · doi:10.1159/000354776 · Cited by 41 · see citing works

Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?

Hancock, S. M., Finkelstein, D. I., & Adlard, P. A. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00137 · Cited by 34 · see citing works

How to Build a Functional Connectomic Biomarker for Mild Cognitive Impairment From Source Reconstructed MEG Resting-State Activity: The Combination of ROI Representation and Connectivity Estimator Matters

Dimitriadis, S. I., López, M. E., Bruña, R., Cuesta, P., Marcos, A., Maestú, F., & Pereda, E. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00306 · Cited by 41 · see citing works

Isolation of synaptic terminals from Alzheimer's disease cortex

Sokolow, S., Henkins, K. M., Williams, I., Vinters, H. V., Schmid, I., Cole, G. M., & Gylys, K. H. (2011) · Cytometry Part A · doi:10.1002/cyto.a.22009 · Cited by 40 · see citing works

Critical role of intraneuronal Aβ in Alzheimer's disease: Technical challenges in studying intracellular Aβ

Gouras, G. K., Willén, K., & Tampellini, D. (2012) · Life Sciences · doi:10.1016/j.lfs.2012.06.004 · Cited by 39 · see citing works

MEG Beamformer-Based Reconstructions of Functional Networks in Mild Cognitive Impairment

López, M. E., Engels, M. M. A., van Straaten, E. C. W., Bajo, R., Delgado‐Losada, M. L., Scheltens, P., Hillebrand, A., Stam, C. J., & Maestú, F. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00107 · Cited by 39 · see citing works

Synaptic dysfunction in Alzheimer's disease: From the role of amyloid β-peptide to the α-secretase ADAM10

Musardo, S., & Marcello, E. E. (2017) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2017.06.018 · Cited by 37 · see citing works

Computational Study of Hippocampal-Septal Theta Rhythm Changes Due to Beta-Amyloid-Altered Ionic Channels

Zou, X., Coyle, D., Wong‐Lin, K., & Maguire, L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021579 · Cited by 36 · see citing works

Pseudo-acetylation of multiple sites on human Tau proteins alters Tau phosphorylation and microtubule binding, and ameliorates amyloid beta toxicity

Gorsky, M. K., Burnouf, S., Sofola-Adesakin, O., Dols, J., Augustin, H., Weigelt, C. M., Grönke, S., & Partridge, L. (2017) · Scientific Reports · doi:10.1038/s41598-017-10225-0 · Cited by 36 · see citing works

Combined effects of aerobic exercise and 40-Hz light flicker exposure on early cognitive impairments in Alzheimer’s disease of 3×Tg mice

Park, S.-S., Park, H.-S., Kim, C., Baek, S., Park, S., Anderson, C., Kim, M.-K., Park, I.-R., & Kim, T.-W. (2022) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00751.2021 · Cited by 34 · see citing works

Targeting Microglia in Alzheimer’s Disease: From Molecular Mechanisms to Potential Therapeutic Targets for Small Molecules

Althafar, Z. M. (2022) · Molecules · doi:10.3390/molecules27134124 · Cited by 35 · see citing works

Neurofibrillary Tangles of Aβx-40 in Alzheimer’s Disease Brains

Lacosta, A.-M., Insua, D., Badi, H., Pesini, P., & Sarasa, M. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-170163 · Cited by 35 · see citing works

Nutraceutical and therapeutic potential of Phycocyanobilin for treating Alzheimer’s disease

Piniella‐Matamoros, B., Marín‐Prida, J., & Pentón‐Rol, G. (2021) · Journal of Biosciences · doi:10.1007/s12038-021-00161-7 · Cited by 34 · see citing works

Involvement of Intracellular and Mitochondrial Aβ in the Ameliorative Effects of Huperzine A against Oligomeric Aβ42-Induced Injury in Primary Rat Neurons

Lei, Y., Yang, L., Ye, C. Y., Qin, M. Y., Yang, H. Y., Jiang, H. L., Tang, X. C., & Zhang, H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0128366 · Cited by 30 · see citing works

Neuropathology of Parkinson’s Disease

Jellinger, K. A. (2014) · Springer eBooks · doi:10.1007/978-3-319-08046-8_2 · Cited by 30 · see citing works

Beta-amyloid induced changes in A-type K+ current can alter hippocampo-septal network dynamics

Zou, X., Coyle, D., Wong‐Lin, K., & Maguire, L. (2011) · Journal of Computational Neuroscience · doi:10.1007/s10827-011-0363-7 · Cited by 27 · see citing works

Post-Translational Modifications of BACE1 in Alzheimer's Disease

Wen, W., Li, P., Liu, P., Xu, S., Wang, F., & Huang, J. H. (2021) · Current Neuropharmacology · doi:10.2174/1570159x19666210121163224 · Cited by 30 · see citing works

Heterogeneous Association of Alzheimer’s Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses

Willén, K. I., Sroka-Oleksiak, A., Takahashi, R. H., & Gouras, G. K. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-170262 · Cited by 27 · see citing works

The γ-Secretase Modulator CHF5074 Reduces the Accumulation of Native Hyperphosphorylated Tau in a Transgenic Mouse Model of Alzheimer’s Disease

Lanzillotta, A., Sarnico, I., Benarese, M., Branca, C., Baiguera, C., Hutter‐Paier, B., Windisch, M., Spano, P., Imbimbo, B. P., & Pizzi, M. (2010) · Journal of Molecular Neuroscience · doi:10.1007/s12031-010-9482-2 · Cited by 27 · see citing works

Divergent topological networks in Alzheimer’s disease: a diffusion kurtosis imaging analysis

Cheng, J.-X., Zhang, H., Peng, Z.-K., Xu, Y. Q., Tang, H., Wu, J., & Xu, J. L. (2018) · Translational Neurodegeneration · doi:10.1186/s40035-018-0115-y · Cited by 26 · see citing works

Knockout of Toll-like receptor 2 attenuates Aβ25–35-induced neurotoxicity in organotypic hippocampal slice cultures

Suh, E. C., Jung, Y. J., Kim, Y. A., Park, E., Lee, S. J., & Lee, K. E. (2013) · Neurochemistry International · doi:10.1016/j.neuint.2013.10.007 · Cited by 24 · see citing works

Topographical Overlapping of the Amyloid-β and Tau Pathologies in the Default Mode Network Predicts Alzheimer’s Disease with Higher Specificity

Hojjati, S. H., Feiz, F., Ozoria, S., Razlighi, Q. R., & Initiative, F. T. A. D. N. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210419 · Cited by 22 · see citing works

APOE4 homozygote females are resistant to the beneficial effects of 17β-estradiol on memory and CA1 dendritic spine density in the EFAD mouse model of Alzheimer's disease

Taxier, L. R., Philippi, S. M., Fleischer, A. W., York, J. M., LaDu, M. J., & Frick, K. M. (2022) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2022.06.005 · Cited by 23 · see citing works

Overexpression of Heme Oxygenase 1 Impairs Cognitive Ability and Changes the Plasticity of the Synapse

Li, L., Peng, Y., Hui, Y., Zhang, S., Zhou, Y. L., Li, D., Li, J., Si, Z., Li, J., Wang, D., et al. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150027 · Cited by 21 · see citing works

Neuroimaging outcomes in clinical trials in Alzheimer's disease

Frisoni, G. B., & Delacourte, A. (2009) · The journal of nutrition health & aging · doi:10.1007/s12603-009-0060-7 · Cited by 20 · see citing works

Alzheimer’s Disease, Drosophila melanogaster and Polyphenols

Jiménez-Del-Río, M., & Velez‐Pardo, C. (2015) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-18365-7_2 · Cited by 20 · see citing works

αν and β1 Integrins Mediate Aβ-Induced Neurotoxicity in Hippocampal Neurons via the FAK Signaling Pathway

Han, H.-Y., Zhang, J.-P., Ji, S.-Q., Liang, Q.-M., Kang, H.-C., Tang, R.-H., Zhu, S.-Q., & Xue, Z. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064839 · Cited by 20 · see citing works

AD-Related N-Terminal Truncated Tau Is Sufficient to Recapitulate In Vivo the Early Perturbations of Human Neuropathology: Implications for Immunotherapy

Borreca, A., Latina, V., Corsetti, V., Middei, S., Piccinin, S., Valle, F. D., Bussani, R., Ammassari‐Teule, M., Nisticò, R., Calissano, P., et al. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-0974-3 · Cited by 18 · see citing works

Understanding the complex interplay between tau, amyloid and the network in the spatiotemporal progression of Alzheimer’s disease

Raj, A., Torok, J., & Ranasinghe, K. G. (2025) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2025.102750 · Cited by 19 · see citing works

Synaptic Protein 1-Takusan Mitigates Amyloid- -Induced Synaptic Loss via Interaction with Tau and Postsynaptic Density-95 at Postsynaptic Sites

Nakanishi, N., Ryan, S. D., Zhang, X., Khan, A. U., Holland, T., Cho, E.-G., Huang, X., Liao, F., Xu, H., Lipton, S. A., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.4646-10.2013 · Cited by 18 · see citing works

Association of CSF proteins with tau and amyloid β levels in asymptomatic 70-year-olds

Remnestål, J., Bergström, S., Olofsson, J., Sjöstedt, E., Uhlén, M., Blennow, K., Zetterberg, H., Zettergren, A., Kern, S., Skoog, I. G., et al. (2021) · Alzheimer s Research & Therapy · doi:10.1186/s13195-021-00789-5 · Cited by 16 · see citing works

Inhalable Thioflavin S for the Detection of Amyloid Beta Deposits in the Retina

Barton, S. M., To, E. C., Rogers, B. P., Whitmore, C. A., Uppal, M., Matsubara, J. A., & Pham, W. N. (2021) · Molecules · doi:10.3390/molecules26040835 · Cited by 17 · see citing works

RNA‐Based Therapies for Neurodegenerative Diseases Targeting Pathogenic Proteins

Rabbani, S. A., El‐Tanani, M., Sharma, S., El‐Tanani, Y., Kumar, R., Saini, M., Yadav, M., Khan, M. A., & Parvez, S. (2025) · European Journal of Neuroscience · doi:10.1111/ejn.70110 · Cited by 15 · see citing works

S4‐02‐02: Aβ42 and tau pathologies are related and begin at synapses

Gouras, G. K. (2010) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2010.05.459

Co-Localization of Amyloid Beta and Tau Pathology in Alzheimer's Disease Synaptosomes

Fein, J. A., Sokolow, S., Miller, C. A., Vinters, H. V., Yang, F., Cole, G. M., & Gylys, K. H. (2008) · American Journal Of Pathology · doi:10.2353/ajpath.2008.070829 · Cited by 203 · see citing works

Human tau increases amyloid β plaque size but not amyloid β‐mediated synapse loss in a novel mouse model of Alzheimer's disease

Jackson, R. J., Rudinskiy, N., Herrmann, A. G., Croft, S., Kim, J. M., Petrova, V., Ramos‐Rodríguez, J. J., Pitstick, R., Wegmann, S., Garcı́a-Alloza, M., et al. (2016) · European Journal of Neuroscience · doi:10.1111/ejn.13442 · Cited by 109 · see citing works

Disentangling the contribution of tau and abeta pathologies in transgenic models of Alzheimer's disease

Sanchez-Varo, R. M., Fernandez-Valenzuela, J. J., Navarro, V., Jiménez, S., Sánchez‐Mejías, E., Nuñez‐Diaz, C., Gómez-Arboledas, Á., Vizuete, M., Dávila, J. C., Vitórica, J., et al. (2018) · Repositorio Institucional de la Universidad de Málaga (University of Málaga)

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

Spires-Jones, T. L., & Hyman, B. T. (2014) · Neuron · doi:10.1016/j.neuron.2014.05.004 · Cited by 1,201 · see citing works