Cited by 152Neural dynamics and brain functionVisual perception and processing mechanismsVisual Attention and Saliency Detection

One-dimensional dynamics of attention and decision making in LIP

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Ganguli, Surya, Bisley, James W., Roitman, Jamie D., Shadlen, Michael N., Goldberg, Michael E., Miller, Kenneth D.·2008·Neuron

Abstract

Where we allocate our visual spatial attention depends upon a continual competition between internally generated goals and external distractions. Recently it was shown that single neurons in the macaque lateral intraparietal area (LIP) can predict the amount of time a distractor can shift the locus of spatial attention away from a goal. We propose that this remarkable dynamical correspondence between single neurons and attention can be explained by a network model in which generically high-dimensional firing-rate vectors rapidly decay to a single mode. We find direct experimental evidence for this model, not only in the original attentional task, but also in a very different task involving perceptual decision making. These results confirm a theoretical prediction that slowly varying activity patterns are proportional to spontaneous activity, pose constraints on models of persistent activity, and suggest a network mechanism for the emergence of robust behavioral timing from heterogeneous neuronal populations.

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Crossref · 10.1016/j.neuron.2008.01.038

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  • The neural population remains one-dimensional during the choice period between first touch and reaction time and starts to increase only at the onset of decision execution and later, in epoch 5.

    “However, in our experiments, the neural population remains one-dimensional (46) during choice period between FT and RT and starts to increase only at the onset of decision execution and later, in epoch 5.”
  • Emergence of synchronous modulation, dimensionality collapse, and strong suppression locked to sensory stimulation are known neural correlates of top-down regulated attention and decision-making processes.

    “Emergence of synchronous modulation (33, 34), dimensionality collapse (46), and strong suppression locked to sensory stimulation (47, 48) are known neural correlates of top–down regulated attention (35) and decision-making processes (3–5).”
  • In LIP data from the RDM experiment, the dynamics within each of the two selective neural pools is dominated by a slow mode.

    “This is consistent with the finding that, in the LIP data recorded from the RDM experiment (Roitman and Shadlen, 2002), the dynamics within each of the two selective neural pools is dominated by a slow mode (Ganguli et al., 2008); thus, the description of two competing neural pools requires two dynamical variables.”

    From Decision Making in Recurrent Neuronal Circuits (2008) · cites this paper as Ganguli et al., 2008

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Authors
Ganguli, S., Bisley, J. W., Roitman, J. D., Shadlen, M. N., Goldberg, M. E., & Miller, K. D.
Affiliations
  • University of California, San Francisco (US)
  • University of California, Los Angeles (US)
  • University of Illinois Chicago (US)
  • Howard Hughes Medical Institute (US)
  • New York State Psychiatric Institute (US)
  • Columbia University (US)
Corresponding author
Ganguli, Surya
Venue
Neuron
Publisher
Elsevier BV
Published
2008-04
Volume
58
Issue
1
Pages
15-25
ISSN
0896-6273 (ISSN-L)
OpenAlex
W2142146307
Cited by
152
References
50
Citations by year
2026: 6 · 2025: 7 · 2024: 11 · 2023: 12 · 2022: 9 · 2021: 8 · 2020: 10 · 2019: 17 · 2018: 3 · 2017: 10 · 2016: 8 · 2015: 4 · 2014: 8 · 2013: 9 · 2012: 5
FWCI
0.64
Type
journal article
Language
en
Open access
Locations
  • Neuron (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • Howard Hughes Medical Institute
  • National Institutes of Health (5r24ey015634-05)
  • National Eye Institute (EY11378, R24 EY-015634, EY 05603, R01EY011001, EY-014978, P30EY019007, EY11001, R01EY017039, R01EY011378, R37EY005603, EY-15634, R01EY005603, R01EY014978)
  • National Center for Research Resources (RR00166, P51RR000166)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
  • Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Visual Attention and Saliency Detection
Keywords
lateral intraparietal area, spatial attention, distractor competition, top-down attention, single-unit activity, network models, firing rate dynamics, persistent activity, perceptual decision making, spontaneous activity, macaque
MeSH terms
Animals, Attention, Decision Making, Humans, Macaca, Nerve Net, Parietal Lobe

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