Behavioral Phenotyping Strategies for Mutant Mice

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Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model

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Atm-Deficient Mice: A Paradigm of Ataxia Telangiectasia

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Schemas and Memory Consolidation.

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Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network

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Characterization of Progressive Motor Deficits in Mice Transgenic for the Human Huntington’s Disease Mutation

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Retrograde Viral Delivery of IGF-1 Prolongs Survival in a Mouse ALS Model

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Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment

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The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents

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The Neuroscience of Mammalian Associative Learning

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Neuronal competition and selection during memory formation

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Neural systems involved in fear and anxiety measured with fear-potentiated startle.

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Altered sexual and social behaviors in trp2 mutant mice

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A Proposed Test Battery and Constellations of Specific Behavioral Paradigms to Investigate the Behavioral Phenotypes of Transgenic and Knockout Mice

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Neuropharmacologic specificity of a simple animal model for the behavioral actions of benzodiazepines

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Different data from different labs: Lessons from studies of gene–environment interaction

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Forebrain-Specific Calcineurin Knockout Selectively Impairs Bidirectional Synaptic Plasticity and Working/Episodic-like Memory

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The neuroendocrine basis of social recognition

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Motor Coordination and Balance in Rodents

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Differences in fear motivated behaviors among inbred mouse strains

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Strain and gender differences in the behavior of mouse lines commonly used in transgenic studies

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Differences in anxiety-related behaviours and in sensitivity to diazepam in inbred and outbred strains of mice

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Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains

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Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task

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Cerebellar circuits and synaptic mechanisms involved in classical eyeblink conditioning

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Rapid Erasure of Long-Term Memory Associations in the Cortex by an Inhibitor of PKMζ

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Genetic and Pharmacological Evidence of a Role for GABAB Receptors in the Modulation of Anxiety- and Antidepressant-Like Behavior

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Altered anxiety‐related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome

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The Cognitive Neuroscience of Memory: An Introduction

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Abnormal anxiety‐related behavior in serotonin transporter null mutant mice: the influence of genetic background

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Behavioural analysis of four mouse strains in an anxiety test battery

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Neuroprotective Effects of Glial Cell Line-Derived Neurotrophic Factor Mediated by an Adeno-Associated Virus Vector in a Transgenic Animal Model of Amyotrophic Lateral Sclerosis

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The use of behavioral test batteries, II: Effect of test interval

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Spatial and nonspatial escape strategies in the Barnes mazePreprint

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Social approach behaviors in oxytocin knockout mice: comparison of two independent lines tested in different laboratory environments

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Immunotherapy for Alzheimer’s disease: Key Symposium: Immunotherapy for Alzheimer’s disease

Morgan, D. (2011) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2010.02315.x · Cited by 225

Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus

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Behavioral and physiological mouse assays for anxiety: a survey in nine mouse strains

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Genetically modified mice and cognition

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Galanin GAL-R1 Receptor Null Mutant Mice Display Increased Anxiety-Like Behavior Specific to the Elevated Plus-Maze

Holmes, A., Kinney, J. W., Wrenn, C. C., Li, Q., Yang, R. J., Ma, L., Vishwanath, J., Saavedra, M. C., Innerfield, C. E., Jacoby, A. S., et al. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300164 · Cited by 202

Targeted gene mutation approaches to the study of anxiety-like behavior in mice

Holmes, A. (2001) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(01)00012-4 · Cited by 200

Using Knockout and Transgenic Mice to Study Neurophysiology and Behavior

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Assessing Reliability, Heritability and General Cognitive Ability in a Battery of Cognitive Tasks for Laboratory Mice

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Baseline exploratory activity predicts anxiolytic responsiveness to diazepam in five mouse strains

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Behavioural profiles of inbred mouse strains used as transgenic backgrounds. II: cognitive tests

Brooks, S. P., Pask, T., Jones, L., & Dunnett, S. B. (2004) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2004.00109.x · Cited by 180

Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease

Steiner, R. A., Hohmann, J. G., Holmes, A., Wrenn, C. C., Cadd, G., Juréus, A., Clifton, D. K., Luo, M., Gutshall, M., Ma, S. Y., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.061445598 · Cited by 176

A comparison of wild-caught wood mice and bank voles in the Intellicage: assessing exploration, daily activity patterns and place learning paradigms

Galsworthy, M. J., Amrein, I., Kuptsov, P. A., Полетаева, И. И., Zinn, P. O., Rau, A., Vyssotski, A. L., & Lipp, H. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2004.06.021 · Cited by 171

Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage

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Establishment and Chimera Analysis of 129/SvEv- and C57BL/6-Derived Mouse Embryonic Stem Cell Lines

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siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

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Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat

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Conditional Inactivation of Presenilin 1 Prevents Amyloid Accumulation and Temporarily Rescues Contextual and Spatial Working Memory Impairments in Amyloid Precursor Protein Transgenic Mice

Saura, C. A., Chen, G., Malkani, S., Choi, S.-Y., Takahashi, R. H., Zhang, D., Gouras, G. K., Kirkwood, A., Morris, R. G. M., & Shen, J. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1247-05.2005 · Cited by 157

Evidence That Long-Term Potentiation Occurs within Individual Hippocampal Synapses during Learning

Fedulov, V., Rex, C. S., Simmons, D. A., Palmer, L. C., Gall, C. M., & LYNCH, G. S. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2003-07.2007 · Cited by 152

Correlations between behaviours in the elevated plus-maze and sensitivity to unpredictable subchronic mild stress: evidence from inbred strains of mice

Ducottet, C., & Belzung, C. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2004.05.018 · Cited by 151

Oral vaccination with a viral vector containing Aβ cDNA attenuates age‐related Aβ accumulation and memory deficits without causing inflammation in a mouse Alzheimer model

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Animal Tests of Anxiety

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Synergy of insulin‐like growth factor‐1 and exercise in amyotrophic lateral sclerosis

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Animal neuropsychology: validation of the intra-dimensional extra-dimensional set shifting task for mice

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Mouse strain differences in autonomic responses to stress

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Behavioral Phenotyping of Transgenic and Knockout Mice: Practical Concerns and Potential Pitfalls

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Contrasting phenotypes of C57BL/6JOlaHsd, 129S2/SvHsd and 129/SvEv mice in two exploration-based tests of anxiety-related behaviour

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Social approach behaviors are similar on conventional versus reverse lighting cycles, and in replications across cohorts, in BTBR T+ tf/J, C57BL/6J, and vasopressin receptor 1B mutant mice

Yang, M. (2007) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.001.2007 · Cited by 124

Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing

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Genetic and dopaminergic modulation of reversal learning in a touchscreen-based operant procedure for mice

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BACE1 gene deletion: Impact on behavioral function in a model of Alzheimer’s disease

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Automated tests for measuring the effects of antidepressants in mice

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The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice

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Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource

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Optimal methods to characterize the G93A mouse model of ALS

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Behavioral differences among fourteen inbred mouse strains commonly used as disease models.

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Galanin receptor subtype 2 (GalR2) null mutant mice display an anxiogenic-like phenotype specific to the elevated plus-maze

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CaMKII Activation in the Entorhinal Cortex Disrupts Previously Encoded Spatial Memory

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An analysis of the genetics of alcohol intoxication in inbred mice

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Discrimination of computer-graphic stimuli by mice: A method for the behavioral characterization of transgenic and gene-knockout models.

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Genetic analysis of anxiety-related behaviors and responses to benzodiazepine-related drugs in AXB and BXA recombinant inbred mouse strains

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Behavioural profiles of inbred mouse strains used as transgenic backgrounds. I: motor tests

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Of mice and men: Reconciling preclinical ALS mouse studies and human clinical trials

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Rodent models for dystonia research: Characteristics, evaluation, and utility

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Measuring cognitive deficits in disabled mice using an automated interactive touchscreen system

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Discrimination of Multidimensional Visual Stimuli by Mice: Intra- and Extradimensional Shifts.

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Discrimination of computer-graphic stimuli by mice: A method for the behavioral characterization of transgenic and gene-knockout models.

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Impact of brain-behavior phenotypying of genetically-engineered mice on research of neuropsychiatric disorders

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