Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
de Calignon, Alix, Polydoro, Manuela, Suárez-Calvet, Marc, William, Christopher, Adamowicz, David H., Kopeikina, Kathy J., Pitstick, Rose, Sahara, Naruhiko +4 more·2012·Neuron
Cited by (1,003)
Items 201–300 of 1,003
- Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1Michel Brahic, Luc Bousset, Gregor Bieri, Ronald Melki, Aaron D. Gitler · 2016 · Acta Neuropathologica
- Synaptic Change in the Posterior Cingulate Gyrus in the Progression of Alzheimer's DiseaseStephen W. Scheff, DOUGLAS A. PRICE, Mubeen A. Ansari, Kelly N. Roberts, Frederick A. Schmitt, Miloš D. Ikonomović, Elliott Jay Mufson · 2014 · Journal of Alzheimer s Disease
- Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal DementiaJinsoo Seo, Oleg Kritskiy, Lauren Ashley Watson, Scarlett J. Barker, Dilip Chandra Dey, Waseem Khan Raja, Yuan-Ta Lin, Tak Ko, Sukhee Cho, Jay Penney et al. · 2017 · Journal of Neuroscience
- Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreadingXu, Yin, Propson, Nicholas E., Du, Shuqi, Xiong, Wen, Zheng, Hui · 2021 · Proceedings of the National Academy of Sciences
- C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell DeathDaniel Kanmert, Adam Cantlon, Christina Muratore, Ming Jin, Tiernan T. O’Malley, Gloria S. Lee, Tracy L. Young‐Pearse, Dennis J. Selkoe, Dominic M. Walsh · 2015 · Journal of Neuroscience
- Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insightJacob W. Vogel, Nick Corriveau‐Lecavalier, Nicolai Franzmeier, Joana B. Pereira, Jesse A. Brown, Anne Maaß, Hugo Botha, William W. Seeley, Dani S. Bassett, David Thomas Jones et al. · 2023 · Nature reviews. Neuroscience
- Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer diseaseZeineh, Michael M., Chen, Yuanxin, Kitzler, Hagen H., Hammond, Robert, Vogel, Hannes, Rutt, Brian K. · 2015 · Neurobiology of Aging
- Cortical tau deposition follows patterns of entorhinal functional connectivity in agingAdams, Jenna N, Maass, Anne, Harrison, Theresa M, Baker, Suzanne L, Jagust, William J · 2019 · eLife
- Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brainPearce, Margaret M. P., Spartz, Ellen J., Hong, Weizhe, Luo, Liqun, Kopito, Ron R. · 2015 · Nature Communications
- Experimental evidence for the age dependence of tau protein spread in the brainWegmann, Susanne, Bennett, Rachel E., Delorme, Louis, Robbins, Ashley B., Hu, Miwei, MacKenzie, Danny, Kirk, Molly J., Schiantarelli, Julia, Tunio, Nahel, Amaral, Ana C. et al. · 2019 · Science Advances
- Basal forebrain volume reliably predicts the cortical spread of Alzheimer’s degenerationSara Fernández‐Cabello, Martin Kronbichler, Koene R. A. Van Dijk, James A Goodman, R. Nathan Spreng, Taylor W. Schmitz, on behalf of the Alzheimer’s Disease Neuroimaging Initiative · 2020 · Brain
- The “glymphatic” mechanism for solute clearance in Alzheimer's disease: game changer or unproven speculation?Alex J. Smith, Alan S. Verkman · 2017 · The FASEB Journal
- Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S TauSamuel J. Jackson, Caroline Kerridge, Jane Cooper, Annalisa Cavallini, Benjamin Falcon, Claire V. Cella, Alessia Landi, Philip G. Szekeres, Tracey K. Murray, Zeshan Ahmed et al. · 2016 · Journal of Neuroscience
- Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer DiseaseLeuzy, Antoine, Smith, Ruben, Cullen, Nicholas C., Strandberg, Olof, Vogel, Jacob W., Binette, Alexa Pichet, Borroni, Edilio, Janelidze, Shorena, Ohlsson, Tomas, Jögi, Jonas et al. · 2022 · JAMA Neurology
- Invited review: Prion‐like transmission and spreading of tau pathologyClavaguera, Florence, Hench, Jürgen, Goedert, Michel, Tolnay, Markus · 2015 · Neuropathology and Applied Neurobiology
- Brain somatic mutations observed in Alzheimer’s disease associated with aging and dysregulation of tau phosphorylationPark, Jun Sung, Lee, Junehawk, Jung, Eun Sun, Kim, Myeong-Heui, Kim, Il Bin, Son, Hyeonju, Kim, Sangwoo, Kim, Sanghyeon, Park, Young Mok, Mook-Jung, Inhee et al. · 2019 · Nature Communications
- Toxic tau: structural origins of tau aggregation in Alzheimer's diseaseAbdullah Al Mamun, Md. Sahab Uddin, Bijo Mathew, Ghulam Md Ashraf · 2020 · Neural Regeneration Research
- Passive immunotherapies targeting Aβ and tau in Alzheimer's diseaseSteven Samuel Plotkin, Neil R. Cashman · 2020 · Neurobiology of Disease
- Intrinsic Connectivity Identifies the Hippocampus as a Main Crossroad between Alzheimer’s and Semantic Dementia-Targeted NetworksRenaud La Joie, Brigitte Landeau, Audrey Perrotin, Alexandre Bejanin, Stéphanie Egret, Alice Pèlerin, Florence Mézenge, Serge Belliard, Vincent de La Sayette, Francis Eustache et al. · 2014 · Neuron
- Mathematical model on Alzheimer’s diseaseWenrui Hao, Avner Friedman · 2016 · BMC Systems Biology
- Spreading of Tau Pathology in Sporadic Alzheimer’s Disease Along Cortico-cortical Top-Down ConnectionsBraak, Heiko, Del Tredici, Kelly · 2018 · Cerebral Cortex
- Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate transporter in a mouse model of Alzheimer's diseaseJoannee Zumkehr, Carlos J. Rodríguez‐Ortiz, David Cheng, Zanett Kieu, Thin Wai, Charlesice Hawkins, Jason Kilian, Sharon Lim, Rodrigo Medeiros, Masashi Kitazawa · 2015 · Neurobiology of Aging
- Alzheimer's Disease Neurodegenerative Biomarkers Are Associated with Decreased Cognitive Function but Not β-Amyloid in Cognitively Normal Older IndividualsWirth, Miranka, Madison, Cindee M., Rabinovici, Gil D., Oh, Hwamee, Landau, Susan M., Jagust, William J. · 2013 · The Journal of Neuroscience
- What is the evidence for chronic concussion-related changes in retired athletes: behavioural, pathological and clinical outcomes?Paul Robert McCrory, Willem H Meeuwisse, Jeffrey S. Kutcher, Barry D. Jordan, Andrew J. Gardner · 2013 · British Journal of Sports Medicine
- The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegenerationMaddalena Costanzo, Chiara Zurzolo · 2013 · Biochemical Journal
- Rational Design of in Vivo Tau Tangle-Selective Near-Infrared Fluorophores: Expanding the BODIPY UniversePeter Verwilst, Hye Ri Kim, Jinho Seo, N Sohn, Seung-Yun Cha, Yeongmin Kim, Sungho Maeng, Jung Won Shin, Jong Hwan Kwak, Chulhun Kang et al. · 2017 · Journal of the American Chemical Society
- Rapid Accumulation of Endogenous Tau Oligomers in a Rat Model of Traumatic Brain InjuryBridget E. Hawkins, Shashirekha Krishnamurthy, Diana Laura Castillo‐Carranza, Urmi Sengupta, Donald S. Prough, George R. Jackson, Douglas S. DeWitt, Rakez Kayed · 2013 · Journal of Biological Chemistry
- Prion-like Mechanisms in the Pathogenesis of Tauopathies and SynucleinopathiesMichel Goedert, Ben Falcon, Florence Clavaguera, Markus Tolnay · 2014 · Current Neurology and Neuroscience Reports
- Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasiaMandelli, Maria Luisa, Vilaplana, Eduard, Brown, Jesse A., Hubbard, H. Isabel, Binney, Richard J., Attygalle, Suneth, Santos-Santos, Miguel A., Miller, Zachary A., Pakvasa, Mikhail, Henry, Maya L. et al. · 2016 · Brain
- The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coinDouglas G. Peters, James R. Connor, Mark D. Meadowcroft · 2015 · Neurobiology of Disease
- Hyperphosphorylation and Cleavage at D421 Enhance Tau SecretionVanessa Plouffe, Nguyen‐Vi Mohamed, Jessica Rivest‐McGraw, Johanne Bertrand, Michel Lauzon, Nicole M. Leclerc · 2012 · PLoS ONE
- Tau Pathology in Chronic Traumatic Encephalopathy and Alzheimer's Disease: Similarities and DifferencesAtsuko Katsumoto, Hideyuki Takeuchi, Fumiaki Tanaka · 2019 · Frontiers in Neurology
- Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificityd’Abramo, Cristina, Acker, Christopher M., Jimenez, Heidy T., Davies, Peter · 2013 · PLoS ONE
- Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy ModelsSethu Sankaranarayanan, Donna M. Barten, Laurel Vana, Nino Devidze, Ling Yang, Gregory W. Cadelina, Nina Hoque, Lynn B. DeCarr, Stefanie Keenan, Alan Lin et al. · 2015 · PLoS ONE
- Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer¿s diseaseHwan‐Ching Tai, Bo Y. Wang, Alberto Serrano‐Pozo, Matthew P. Frosch, Tara L. Spires‐Jones, Bradley T. Hyman · 2014 · Acta Neuropathologica Communications
- Widespread tau seeding activity at early Braak stagesJennifer L. Furman, Jaime Vaquer‐Alicea, Charles L. White, Nigel J. Cairns, Peter T. Nelson, Marc I. Diamond · 2016 · Acta Neuropathologica
- Cell-to-Cell Transmission of Tau and α-SynucleinNorihito Uemura, Maiko T. Uemura, Kelvin C. Luk, Virginia M.‐Y. Lee, John Q. Trojanowski · 2020 · Trends in Molecular Medicine
- Neuroinflammatory responses in Alzheimer’s diseaseCira Dansokho, Michael Thomas Heneka · 2017 · Journal of Neural Transmission
- Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic miceStancu, Ilie-Cosmin, Vasconcelos, Bruno, Ris, Laurence, Wang, Peng, Villers, Agnès, Peeraer, Eve, Buist, Arjan, Terwel, Dick, Baatsen, Peter, Oyelami, Tutu et al. · 2015 · Acta Neuropathologica
- The six brain‐specific TAU isoforms and their role in Alzheimer's disease and related neurodegenerative dementia syndromesSarah Buchholz, Hans Zempel · 2024 · Alzheimer s & Dementia
- Role of Aβ in Alzheimer’s-related synaptic dysfunctionHuiqin Zhang, Xuefan Jiang, Lina Ma, Wei Wei, Zehui Li, Surui Chang, Jiayu Wen, Jiahui Sun, Hao Li · 2022 · Frontiers in Cell and Developmental Biology
- The aged rhesus macaque manifests Braak stage III/IV Alzheimer's‐like pathologyPaspalas, Constantinos D., Carlyle, Becky C., Leslie, Shannon, Preuss, Todd M., Crimins, Johanna L., Huttner, Anita J., van Dyck, Christopher H., Rosene, Douglas L., Nairn, Angus C., Arnsten, Amy F.T. · 2018 · Alzheimer's & Dementia
- Aging in the olfactory systemArie Sitthichai Mobley, Diego J. Rodriguez‐Gil, Fumiaki Imamura, Charles A. Greer · 2013 · Trends in Neurosciences
- Paired Helical Filaments from Alzheimer Disease Brain Induce Intracellular Accumulation of Tau Protein in AggresomesIsmael Santa‐María, Merina Varghese, Hanna Ksiȩżak-Reding, Anastasiya Dzhun, Jun Wang, Giulio Maria Pasinetti · 2012 · Journal of Biological Chemistry
- Linking Traumatic Brain Injury to Chronic Traumatic Encephalopathy: Identification of Potential Mechanisms Leading to Neurofibrillary Tangle DevelopmentBrandon Peter Lucke-Wold, Ryan Coddington Turner, Aric Flint Logsdon, Julian E. Bailes, Jason Delwyn Huber, Charles Lee Rosen · 2014 · Journal of Neurotrauma
- Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau depositionMaj‐Linda B. Selenica, Leif Benner, Steven B. Housley, Barbara Manchec, Daniel C. Lee, Kevin R. Nash, Jay H. Kalin, Joel A. Bergman, Alan P. Kozikowski, Marcia N. Gordon et al. · 2014 · Alzheimer s Research & Therapy
- cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortexCarlyle, Becky C., Nairn, Angus C., Wang, Min, Yang, Yang, Jin, Lu E., Simen, Arthur A., Ramos, Brian P., Bordner, Kelly A., Craft, George E., Davies, Peter et al. · 2014 · Proceedings of the National Academy of Sciences
- Tau: From research to clinical developmentHoltzman, David M., Carrillo, Maria C., Hendrix, James A., Bain, Lisa J., Catafau, Ana M., Gault, Laura M., Goedert, Michel, Mandelkow, Eckhard, Mandelkow, Eva‐Maria, Miller, David S. et al. · 2016 · Alzheimer's & Dementia
- Formation and Propagation of Tau Oligomeric SeedsJulia E. Gerson, Rakez Kayed · 2013 · Frontiers in Neurology
- Pre‐synaptic C‐terminal truncated tau is released from cortical synapses in Alzheimer's diseaseSokolow, Sophie, Henkins, Kristen M., Bilousova, Tina, Gonzalez, Bianca, Vinters, Harry V., Miller, Carol A., Cornwell, Lindsey, Poon, Wayne W., Gylys, Karen H. · 2015 · Journal of Neurochemistry
- Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicityWegmann, Susanne, Maury, Eduardo A, Kirk, Molly J, Saqran, Lubna, Roe, Allyson, DeVos, Sarah L, Nicholls, Samantha, Fan, Zhanyun, Takeda, Shuko, Cagsal‐Getkin, Ozge et al. · 2015 · The EMBO Journal
- Atherosclerosis and Alzheimer - diseases with a common cause? Inflammation, oxysterols, vasculatureRichard Lathe, Alexandra A. Tsitrina, Yuri V. Kotelevtsev · 2014 · BMC Geriatrics
- Gut inflammation triggers C/EBPβ/δ‐secretase‐dependent gut‐to‐brain propagation of Aβ and Tau fibrils in Alzheimer’s diseaseChun Chen, Yunzhe Zhou, Hualong Wang, Ashfaqul M. Alam, Seong Su Kang, Eun Hee Ahn, Xia Liu, Jianping Jia, Keqiang Ye · 2021 · The EMBO Journal
- Tau pathology in neurodegenerative disease: disease mechanisms and therapeutic avenuesNiyatee P. Samudra, Courtney Lane‐Donovan, Lawren A. VandeVrede, Adam L. Boxer · 2023 · Journal of Clinical Investigation
- Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive DeficitsJulie A. Harris, Akihiko Koyama, Sumihiro Maeda, Kaitlyn Ho, Nino Devidze, Dena B. Dubal, Gui-Qiu Yu, Eliezer Masliah, Lennart Mucke · 2012 · PLoS ONE
- Induction of a transmissible tau pathology by traumatic brain injuryZanier, Elisa R, Bertani, Ilaria, Sammali, Eliana, Pischiutta, Francesca, Chiaravalloti, Maria Antonietta, Vegliante, Gloria, Masone, Antonio, Corbelli, Alessandro, Smith, Douglas H, Menon, David K et al. · 2018 · Brain
- Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregatesBrelstaff, Jack H., Mason, Matthew, Katsinelos, Taxiarchis, McEwan, William A., Ghetti, Bernardino, Tolkovsky, Aviva M., Spillantini, Maria Grazia · 2021 · Science Advances
- Research Gaps and Controversies in Chronic Traumatic Encephalopathy: A ReviewAsken, Breton M., Sullan, Molly J., DeKosky, Steven T., Jaffee, Michael S., Bauer, Russell M. · 2017 · JAMA Neurology
- Challenges of multimorbidity of the aging brain: a critical updateJellinger, Kurt A., Attems, Johannes · 2015 · Journal of Neural Transmission
- β-Amyloid and the Pathomechanisms of Alzheimer’s Disease: A Comprehensive ViewBotond Penke, Ferenc Bogár, Lívia Fülöp · 2017 · Molecules
- Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseasesMartin Kampmann · 2024 · Nature reviews. Neuroscience
- The role of extracellular Tau in the spreading of neurofibrillary pathologyMedina, Miguel, Avila, Jesús · 2014 · Frontiers in Cellular Neuroscience
- Therapeutic strategies for tau mediated neurodegenerationYasumasa Yoshiyama, Virginia M.‐Y. Lee, John Q. Trojanowski · 2012 · Journal of Neurology Neurosurgery & Psychiatry
- Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer TauJean‐Philippe Courade, Rachel C. Angers, Georges Mairet‐Coello, Nathalie Pacico, Kerry L. Tyson, Daniel J. Lightwood, Rebecca Munro, David McMillan, Robert Griffin, TERRY S. BAKER et al. · 2018 · Acta Neuropathologica
- “Prion‐Like” Templated Misfolding in TauopathiesFlorence Clavaguera, Isabelle Lavenir, Ben Falcon, Stephan Frank, Michel Goedert, Markus Tolnay · 2013 · Brain Pathology
- Emerging Roles of Astrocytes in Neuro-Vascular Unit and the Tripartite Synapse With Emphasis on Reactive Gliosis in the Context of Alzheimer’s DiseaseLiu, Cai-Yun, Yang, Yu, Ju, Wei-Na, Wang, Xu, Zhang, Hong-Liang · 2018 · Frontiers in Cellular Neuroscience
- In vivo rate-determining steps of tau seed accumulation in Alzheimer’s diseaseMeisl, Georg, Hidari, Eric, Allinson, Kieren, Rittman, Timothy, DeVos, Sarah L., Sanchez, Justin S., Xu, Catherine K., Duff, Karen E., Johnson, Keith A., Rowe, James B. et al. · 2021 · Science Advances
- Hyperphosphorylation determines both the spread and the morphology of tau pathologyWen Hui Hu, Xinhua Zhang, Yunn Chyn Tung, Shu-Tao Xie, Fei Liu, Khalid Iqbal · 2016 · Alzheimer s & Dementia
- Transgenic Mouse Models of Alzheimer’s Disease: An Integrative AnalysisRaquel Maria Sanchez-Varo, Marina Mejias‐Ortega, Juan José Fernandez-Valenzuela, Cristina Nuñez‐Diaz, Laura Cáceres-Palomo, Laura Vegas‐Gomez, Elisabeth Sánchez‐Mejías, Laura Trujillo‐Estrada, Juan Antonio García‐León, Inés Moreno‐González et al. · 2022 · International Journal of Molecular Sciences
- Micropublications: a semantic model for claims, evidence, arguments and annotations in biomedical communicationsTim Clark, Paolo Ciccarese, Carole Goble · 2014 · Journal of Biomedical Semantics
- Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease2022
- Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in VitroNobuhara, Chloe K., DeVos, Sarah L., Commins, Caitlin, Wegmann, Susanne, Moore, Benjamin D., Roe, Allyson D., Costantino, Isabel, Frosch, Matthew P., Pitstick, Rose, Carlson, George A. et al. · 2017 · The American Journal of Pathology
- Biophysical Insights into How Surfaces, Including Lipid Membranes, Modulate Protein Aggregation Related to NeurodegenerationBurke, Kathleen A., Yates, Elizabeth A., Legleiter, Justin · 2013 · Frontiers in Neurology
- Trem2 deletion enhances tau dispersion and pathology through microglia exosomesZhu, Bing, Liu, Yan, Hwang, Spring, Archuleta, Kailey, Huang, Huijie, Campos, Alex, Murad, Rabi, Piña-Crespo, Juan, Xu, Huaxi, Huang, Timothy Y. · 2022 · Molecular Neurodegeneration
- Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivoJin Miao, Ruirui Shi, Longfei Li, Feng Chen, Yan Zhou, Yunn Chyn Tung, Wen Hui Hu, Cheng‐Xin Gong, Khalid Iqbal, Fei Liu · 2019 · Frontiers in Aging Neuroscience
- TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreadingYin Xu, Shuqi Du, Jacob A. Marsh, Kanta Horie, Chihiro Sato, Andrea Ballabio, Celeste M M. Karch, David M. Holtzman, Hui Zheng · 2020 · Molecular Psychiatry
- Chronic neurodegenerative consequences of traumatic brain injuryNeelima B. Chauhan · 2014 · Restorative Neurology and Neuroscience
- Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial EngagementLee, Seung-Hye, Le Pichon, Claire E., Adolfsson, Oskar, Gafner, Valérie, Pihlgren, Maria, Lin, Han, Solanoy, Hilda, Brendza, Robert, Ngu, Hai, Foreman, Oded et al. · 2016 · Cell Reports
- Synaptic alterations in the rTg4510 mouse model of tauopathyKatherine J. Kopeikina, Manuela Polydoro, Hwan‐Ching Tai, Erich Yaeger, George A. Carlson, Rose Pitstick, Bradley T. Hyman, Tara L. Spires‐Jones · 2012 · The Journal of Comparative Neurology
- The prion model for progression and diversity of neurodegenerative diseasesBarbara Elena Stopschinski, Marc I. Diamond · 2017 · The Lancet Neurology
- Can we prevent Alzheimer's disease? Secondary “prevention” trials in Alzheimer's diseaseMaría C. Carrillo, H. Robert Brashear, Veronika Logovinsky, J. Michael Ryan, Howard Feldman, Eric Siemers, Susan R. Abushakra, Dean M. Hartley, Ronald Carl Petersen, Ara S. Khachaturian et al. · 2013 · Alzheimer s & Dementia
- 18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal personsDavid S. Knopman, Clifford R. Jack, Heather J. Wiste, Emily S. Lundt, Stephen D. Weigand, Prashanthi Vemuri, Val J. Lowe, Kejal Kantarci, Jeffrey L. Gunter, Matthew L. Senjem et al. · 2014 · Neurobiology of Aging
- Propagation of tau pathology in Alzheimer’s disease: identification of novel therapeutic targetsAmy M. Pooler, Manuela Polydoro, Susanne Wegmann, Samantha B. Nicholls, Tara L. Spires‐Jones, Bradley T. Hyman · 2013 · Alzheimer s Research & Therapy
- The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type TauopathyRobert Siman, R. Cocca, Yina Dong · 2015 · PLoS ONE
- Microglia in Alzheimer’s Disease in the Context of Tau PathologyJuan Ramón Perea, Marta Bolós, Jesús Ávila · 2020 · Biomolecules
- Intrinsic connectivity networks in healthy subjects explain clinical variability in Alzheimer’s diseaseLehmann, Manja, Madison, Cindee M., Ghosh, Pia M., Seeley, William W., Mormino, Elizabeth, Greicius, Michael D., Gorno-Tempini, Maria Luisa, Kramer, Joel H., Miller, Bruce L., Jagust, William J. et al. · 2013 · Proceedings of the National Academy of Sciences
- Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolismCooper, Joanna M., Lathuiliere, Aurelien, Migliorini, Mary, Arai, Allison L., Wani, Mashhood M., Dujardin, Simon, Muratoglu, Selen C., Hyman, Bradley T., Strickland, Dudley K. · 2021 · Journal of Biological Chemistry
- The Role of Microglia in the Spread of Tau: Relevance for TauopathiesJuan Ramón Perea, Marı́a Llorens-Martı́n, Jesús Ávila, Marta Bolós · 2018 · Frontiers in Cellular Neuroscience
- Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease modelPolydoro, Manuela, Dzhala, Volodymyr I., Pooler, Amy M., Nicholls, Samantha B., McKinney, A. Patrick, Sanchez, Laura, Pitstick, Rose, Carlson, George A., Staley, Kevin J., Spires-Jones, Tara L. et al. · 2014 · Acta Neuropathologica
- Neuronal Network Excitability in Alzheimer’s Disease: The Puzzle of Similar versus Divergent Roles of Amyloid β and TauSyed Faraz Kazim, Joon Ho Seo, Riccardo Bianchi, Chloe S. Larson, Abhijeet Sharma, Robert K. S. Wong, Kirill Gorbachev, Ana C. Pereira · 2021 · eNeuro
- The dendritic hypothesis for Alzheimer's disease pathophysiologyCochran, J. Nicholas, Hall, Alicia M., Roberson, Erik D. · 2014 · Brain Research Bulletin
- The Role of Tau Oligomers in the Onset of Alzheimer's Disease NeuropathologyCárdenas-Aguayo, María del Carmen, Gómez-Virgilio, Laura, DeRosa, Steven, Meraz-Ríos, Marco Antonio · 2014 · ACS Chemical Neuroscience
- Alzheimer's Disease Mechanisms and Emerging Roads to Novel TherapeuticsSala Frigerio, Carlo, De Strooper, Bart · 2016 · Annual Review of Neuroscience
- Tunneling-nanotube direction determination in neurons and astrocytesXiaolin Sun, Y Wang, Jiayi Zhang, Jie Tu, X-J Wang, X-D Su, Li Wang, Yan Zhang · 2012 · Cell Death and Disease
- In vivo characterization of the early states of the amyloid-beta networkSepulcre, Jorge, Sabuncu, Mert R., Becker, Alex, Sperling, Reisa, Johnson, Keith A. · 2013 · Brain
- Seed‐competent high‐molecular‐weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patientsTakeda, Shuko, Commins, Caitlin, DeVos, Sarah L., Nobuhara, Chloe K., Wegmann, Susanne, Roe, Allyson D., Costantino, Isabel, Fan, Zhanyun, Nicholls, Samantha B., Sherman, Alexis E. et al. · 2016 · Annals of Neurology
- The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memoryFranzmeier, Nicolai, Rubinski, Anna, Neitzel, Julia, Ewers, Michael, The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Weiner, Michael W., Aisen, Paul, Petersen, Ronald, Jack, Clifford R., Jagust, William et al. · 2019 · Nature Communications
- Alzheimer diseaseJustin M. Nussbaum, Matthew E. Seward, George S. Bloom · 2013 · Prion
- Patient-Tailored, Connectivity-Based Forecasts of Spreading Brain AtrophyJesse A. Brown, Jersey Deng, John M Neuhaus, Isabel J. Sible, Ana C. Sias, Suzee E. Lee, John Kornak, Gabe A. Marx, Anna M. Karydas, Salvatore Spina et al. · 2019 · Neuron
- Contribution of astrocytes to neuropathology of neurodegenerative diseasesÇiğdem Acıoğlu, Lun Li, Stella Elkabes · 2021 · Brain Research