Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

de Calignon, Alix, Polydoro, Manuela, Suárez-Calvet, Marc, William, Christopher, Adamowicz, David H., Kopeikina, Kathy J., Pitstick, Rose, Sahara, Naruhiko +4 more·2012·Neuron

Cited by (1,003)

Items 201–300 of 1,003

  1. Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1
    Michel Brahic, Luc Bousset, Gregor Bieri, Ronald Melki, Aaron D. Gitler · 2016 · Acta Neuropathologica
  2. Synaptic Change in the Posterior Cingulate Gyrus in the Progression of Alzheimer's Disease
    Stephen W. Scheff, DOUGLAS A. PRICE, Mubeen A. Ansari, Kelly N. Roberts, Frederick A. Schmitt, Miloš D. Ikonomović, Elliott Jay Mufson · 2014 · Journal of Alzheimer s Disease
  3. Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia
    Jinsoo Seo, Oleg Kritskiy, Lauren Ashley Watson, Scarlett J. Barker, Dilip Chandra Dey, Waseem Khan Raja, Yuan-Ta Lin, Tak Ko, Sukhee Cho, Jay Penney et al. · 2017 · Journal of Neuroscience
  4. Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreading
    Xu, Yin, Propson, Nicholas E., Du, Shuqi, Xiong, Wen, Zheng, Hui · 2021 · Proceedings of the National Academy of Sciences
  5. C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death
    Daniel Kanmert, Adam Cantlon, Christina Muratore, Ming Jin, Tiernan T. O’Malley, Gloria S. Lee, Tracy L. Young‐Pearse, Dennis J. Selkoe, Dominic M. Walsh · 2015 · Journal of Neuroscience
  6. Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insight
    Jacob W. Vogel, Nick Corriveau‐Lecavalier, Nicolai Franzmeier, Joana B. Pereira, Jesse A. Brown, Anne Maaß, Hugo Botha, William W. Seeley, Dani S. Bassett, David Thomas Jones et al. · 2023 · Nature reviews. Neuroscience
  7. Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease
    Zeineh, Michael M., Chen, Yuanxin, Kitzler, Hagen H., Hammond, Robert, Vogel, Hannes, Rutt, Brian K. · 2015 · Neurobiology of Aging
  8. Cortical tau deposition follows patterns of entorhinal functional connectivity in aging
    Adams, Jenna N, Maass, Anne, Harrison, Theresa M, Baker, Suzanne L, Jagust, William J · 2019 · eLife
  9. Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain
    Pearce, Margaret M. P., Spartz, Ellen J., Hong, Weizhe, Luo, Liqun, Kopito, Ron R. · 2015 · Nature Communications
  10. Experimental evidence for the age dependence of tau protein spread in the brain
    Wegmann, Susanne, Bennett, Rachel E., Delorme, Louis, Robbins, Ashley B., Hu, Miwei, MacKenzie, Danny, Kirk, Molly J., Schiantarelli, Julia, Tunio, Nahel, Amaral, Ana C. et al. · 2019 · Science Advances
  11. Basal forebrain volume reliably predicts the cortical spread of Alzheimer’s degeneration
    Sara Fernández‐Cabello, Martin Kronbichler, Koene R. A. Van Dijk, James A Goodman, R. Nathan Spreng, Taylor W. Schmitz, on behalf of the Alzheimer’s Disease Neuroimaging Initiative · 2020 · Brain
  12. The “glymphatic” mechanism for solute clearance in Alzheimer's disease: game changer or unproven speculation?
    Alex J. Smith, Alan S. Verkman · 2017 · The FASEB Journal
  13. Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau
    Samuel J. Jackson, Caroline Kerridge, Jane Cooper, Annalisa Cavallini, Benjamin Falcon, Claire V. Cella, Alessia Landi, Philip G. Szekeres, Tracey K. Murray, Zeshan Ahmed et al. · 2016 · Journal of Neuroscience
  14. Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer Disease
    Leuzy, Antoine, Smith, Ruben, Cullen, Nicholas C., Strandberg, Olof, Vogel, Jacob W., Binette, Alexa Pichet, Borroni, Edilio, Janelidze, Shorena, Ohlsson, Tomas, Jögi, Jonas et al. · 2022 · JAMA Neurology
  15. Invited review: Prion‐like transmission and spreading of tau pathology
    Clavaguera, Florence, Hench, Jürgen, Goedert, Michel, Tolnay, Markus · 2015 · Neuropathology and Applied Neurobiology
  16. Brain somatic mutations observed in Alzheimer’s disease associated with aging and dysregulation of tau phosphorylation
    Park, Jun Sung, Lee, Junehawk, Jung, Eun Sun, Kim, Myeong-Heui, Kim, Il Bin, Son, Hyeonju, Kim, Sangwoo, Kim, Sanghyeon, Park, Young Mok, Mook-Jung, Inhee et al. · 2019 · Nature Communications
  17. Toxic tau: structural origins of tau aggregation in Alzheimer's disease
    Abdullah Al Mamun, Md. Sahab Uddin, Bijo Mathew, Ghulam Md Ashraf · 2020 · Neural Regeneration Research
  18. Passive immunotherapies targeting Aβ and tau in Alzheimer's disease
    Steven Samuel Plotkin, Neil R. Cashman · 2020 · Neurobiology of Disease
  19. Intrinsic Connectivity Identifies the Hippocampus as a Main Crossroad between Alzheimer’s and Semantic Dementia-Targeted Networks
    Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Alexandre Bejanin, Stéphanie Egret, Alice Pèlerin, Florence Mézenge, Serge Belliard, Vincent de La Sayette, Francis Eustache et al. · 2014 · Neuron
  20. Mathematical model on Alzheimer’s disease
    Wenrui Hao, Avner Friedman · 2016 · BMC Systems Biology
  21. Spreading of Tau Pathology in Sporadic Alzheimer’s Disease Along Cortico-cortical Top-Down Connections
    Braak, Heiko, Del Tredici, Kelly · 2018 · Cerebral Cortex
  22. Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate transporter in a mouse model of Alzheimer's disease
    Joannee Zumkehr, Carlos J. Rodríguez‐Ortiz, David Cheng, Zanett Kieu, Thin Wai, Charlesice Hawkins, Jason Kilian, Sharon Lim, Rodrigo Medeiros, Masashi Kitazawa · 2015 · Neurobiology of Aging
  23. Alzheimer's Disease Neurodegenerative Biomarkers Are Associated with Decreased Cognitive Function but Not β-Amyloid in Cognitively Normal Older Individuals
    Wirth, Miranka, Madison, Cindee M., Rabinovici, Gil D., Oh, Hwamee, Landau, Susan M., Jagust, William J. · 2013 · The Journal of Neuroscience
  24. What is the evidence for chronic concussion-related changes in retired athletes: behavioural, pathological and clinical outcomes?
    Paul Robert McCrory, Willem H Meeuwisse, Jeffrey S. Kutcher, Barry D. Jordan, Andrew J. Gardner · 2013 · British Journal of Sports Medicine
  25. The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration
    Maddalena Costanzo, Chiara Zurzolo · 2013 · Biochemical Journal
  26. Rational Design of in Vivo Tau Tangle-Selective Near-Infrared Fluorophores: Expanding the BODIPY Universe
    Peter Verwilst, Hye Ri Kim, Jinho Seo, N Sohn, Seung-Yun Cha, Yeongmin Kim, Sungho Maeng, Jung Won Shin, Jong Hwan Kwak, Chulhun Kang et al. · 2017 · Journal of the American Chemical Society
  27. Rapid Accumulation of Endogenous Tau Oligomers in a Rat Model of Traumatic Brain Injury
    Bridget E. Hawkins, Shashirekha Krishnamurthy, Diana Laura Castillo‐Carranza, Urmi Sengupta, Donald S. Prough, George R. Jackson, Douglas S. DeWitt, Rakez Kayed · 2013 · Journal of Biological Chemistry
  28. Prion-like Mechanisms in the Pathogenesis of Tauopathies and Synucleinopathies
    Michel Goedert, Ben Falcon, Florence Clavaguera, Markus Tolnay · 2014 · Current Neurology and Neuroscience Reports
  29. Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasia
    Mandelli, Maria Luisa, Vilaplana, Eduard, Brown, Jesse A., Hubbard, H. Isabel, Binney, Richard J., Attygalle, Suneth, Santos-Santos, Miguel A., Miller, Zachary A., Pakvasa, Mikhail, Henry, Maya L. et al. · 2016 · Brain
  30. The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin
    Douglas G. Peters, James R. Connor, Mark D. Meadowcroft · 2015 · Neurobiology of Disease
  31. Hyperphosphorylation and Cleavage at D421 Enhance Tau Secretion
    Vanessa Plouffe, Nguyen‐Vi Mohamed, Jessica Rivest‐McGraw, Johanne Bertrand, Michel Lauzon, Nicole M. Leclerc · 2012 · PLoS ONE
  32. Tau Pathology in Chronic Traumatic Encephalopathy and Alzheimer's Disease: Similarities and Differences
    Atsuko Katsumoto, Hideyuki Takeuchi, Fumiaki Tanaka · 2019 · Frontiers in Neurology
  33. Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity
    d’Abramo, Cristina, Acker, Christopher M., Jimenez, Heidy T., Davies, Peter · 2013 · PLoS ONE
  34. Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy Models
    Sethu Sankaranarayanan, Donna M. Barten, Laurel Vana, Nino Devidze, Ling Yang, Gregory W. Cadelina, Nina Hoque, Lynn B. DeCarr, Stefanie Keenan, Alan Lin et al. · 2015 · PLoS ONE
  35. Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer¿s disease
    Hwan‐Ching Tai, Bo Y. Wang, Alberto Serrano‐Pozo, Matthew P. Frosch, Tara L. Spires‐Jones, Bradley T. Hyman · 2014 · Acta Neuropathologica Communications
  36. Widespread tau seeding activity at early Braak stages
    Jennifer L. Furman, Jaime Vaquer‐Alicea, Charles L. White, Nigel J. Cairns, Peter T. Nelson, Marc I. Diamond · 2016 · Acta Neuropathologica
  37. Cell-to-Cell Transmission of Tau and α-Synuclein
    Norihito Uemura, Maiko T. Uemura, Kelvin C. Luk, Virginia M.‐Y. Lee, John Q. Trojanowski · 2020 · Trends in Molecular Medicine
  38. Neuroinflammatory responses in Alzheimer’s disease
    Cira Dansokho, Michael Thomas Heneka · 2017 · Journal of Neural Transmission
  39. Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice
    Stancu, Ilie-Cosmin, Vasconcelos, Bruno, Ris, Laurence, Wang, Peng, Villers, Agnès, Peeraer, Eve, Buist, Arjan, Terwel, Dick, Baatsen, Peter, Oyelami, Tutu et al. · 2015 · Acta Neuropathologica
  40. The six brain‐specific TAU isoforms and their role in Alzheimer's disease and related neurodegenerative dementia syndromes
    Sarah Buchholz, Hans Zempel · 2024 · Alzheimer s & Dementia
  41. Role of Aβ in Alzheimer’s-related synaptic dysfunction
    Huiqin Zhang, Xuefan Jiang, Lina Ma, Wei Wei, Zehui Li, Surui Chang, Jiayu Wen, Jiahui Sun, Hao Li · 2022 · Frontiers in Cell and Developmental Biology
  42. The aged rhesus macaque manifests Braak stage III/IV Alzheimer's‐like pathology
    Paspalas, Constantinos D., Carlyle, Becky C., Leslie, Shannon, Preuss, Todd M., Crimins, Johanna L., Huttner, Anita J., van Dyck, Christopher H., Rosene, Douglas L., Nairn, Angus C., Arnsten, Amy F.T. · 2018 · Alzheimer's & Dementia
  43. Aging in the olfactory system
    Arie Sitthichai Mobley, Diego J. Rodriguez‐Gil, Fumiaki Imamura, Charles A. Greer · 2013 · Trends in Neurosciences
  44. Paired Helical Filaments from Alzheimer Disease Brain Induce Intracellular Accumulation of Tau Protein in Aggresomes
    Ismael Santa‐María, Merina Varghese, Hanna Ksiȩżak-Reding, Anastasiya Dzhun, Jun Wang, Giulio Maria Pasinetti · 2012 · Journal of Biological Chemistry
  45. Linking Traumatic Brain Injury to Chronic Traumatic Encephalopathy: Identification of Potential Mechanisms Leading to Neurofibrillary Tangle Development
    Brandon Peter Lucke-Wold, Ryan Coddington Turner, Aric Flint Logsdon, Julian E. Bailes, Jason Delwyn Huber, Charles Lee Rosen · 2014 · Journal of Neurotrauma
  46. Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition
    Maj‐Linda B. Selenica, Leif Benner, Steven B. Housley, Barbara Manchec, Daniel C. Lee, Kevin R. Nash, Jay H. Kalin, Joel A. Bergman, Alan P. Kozikowski, Marcia N. Gordon et al. · 2014 · Alzheimer s Research & Therapy
  47. cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex
    Carlyle, Becky C., Nairn, Angus C., Wang, Min, Yang, Yang, Jin, Lu E., Simen, Arthur A., Ramos, Brian P., Bordner, Kelly A., Craft, George E., Davies, Peter et al. · 2014 · Proceedings of the National Academy of Sciences
  48. Tau: From research to clinical development
    Holtzman, David M., Carrillo, Maria C., Hendrix, James A., Bain, Lisa J., Catafau, Ana M., Gault, Laura M., Goedert, Michel, Mandelkow, Eckhard, Mandelkow, Eva‐Maria, Miller, David S. et al. · 2016 · Alzheimer's & Dementia
  49. Formation and Propagation of Tau Oligomeric Seeds
    Julia E. Gerson, Rakez Kayed · 2013 · Frontiers in Neurology
  50. Pre‐synaptic C‐terminal truncated tau is released from cortical synapses in Alzheimer's disease
    Sokolow, Sophie, Henkins, Kristen M., Bilousova, Tina, Gonzalez, Bianca, Vinters, Harry V., Miller, Carol A., Cornwell, Lindsey, Poon, Wayne W., Gylys, Karen H. · 2015 · Journal of Neurochemistry
  51. Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity
    Wegmann, Susanne, Maury, Eduardo A, Kirk, Molly J, Saqran, Lubna, Roe, Allyson, DeVos, Sarah L, Nicholls, Samantha, Fan, Zhanyun, Takeda, Shuko, Cagsal‐Getkin, Ozge et al. · 2015 · The EMBO Journal
  52. Atherosclerosis and Alzheimer - diseases with a common cause? Inflammation, oxysterols, vasculature
    Richard Lathe, Alexandra A. Tsitrina, Yuri V. Kotelevtsev · 2014 · BMC Geriatrics
  53. Gut inflammation triggers C/EBPβ/δ‐secretase‐dependent gut‐to‐brain propagation of Aβ and Tau fibrils in Alzheimer’s disease
    Chun Chen, Yunzhe Zhou, Hualong Wang, Ashfaqul M. Alam, Seong Su Kang, Eun Hee Ahn, Xia Liu, Jianping Jia, Keqiang Ye · 2021 · The EMBO Journal
  54. Tau pathology in neurodegenerative disease: disease mechanisms and therapeutic avenues
    Niyatee P. Samudra, Courtney Lane‐Donovan, Lawren A. VandeVrede, Adam L. Boxer · 2023 · Journal of Clinical Investigation
  55. Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive Deficits
    Julie A. Harris, Akihiko Koyama, Sumihiro Maeda, Kaitlyn Ho, Nino Devidze, Dena B. Dubal, Gui-Qiu Yu, Eliezer Masliah, Lennart Mucke · 2012 · PLoS ONE
  56. Induction of a transmissible tau pathology by traumatic brain injury
    Zanier, Elisa R, Bertani, Ilaria, Sammali, Eliana, Pischiutta, Francesca, Chiaravalloti, Maria Antonietta, Vegliante, Gloria, Masone, Antonio, Corbelli, Alessandro, Smith, Douglas H, Menon, David K et al. · 2018 · Brain
  57. Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates
    Brelstaff, Jack H., Mason, Matthew, Katsinelos, Taxiarchis, McEwan, William A., Ghetti, Bernardino, Tolkovsky, Aviva M., Spillantini, Maria Grazia · 2021 · Science Advances
  58. Research Gaps and Controversies in Chronic Traumatic Encephalopathy: A Review
    Asken, Breton M., Sullan, Molly J., DeKosky, Steven T., Jaffee, Michael S., Bauer, Russell M. · 2017 · JAMA Neurology
  59. Challenges of multimorbidity of the aging brain: a critical update
    Jellinger, Kurt A., Attems, Johannes · 2015 · Journal of Neural Transmission
  60. β-Amyloid and the Pathomechanisms of Alzheimer’s Disease: A Comprehensive View
    Botond Penke, Ferenc Bogár, Lívia Fülöp · 2017 · Molecules
  61. Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases
    Martin Kampmann · 2024 · Nature reviews. Neuroscience
  62. The role of extracellular Tau in the spreading of neurofibrillary pathology
    Medina, Miguel, Avila, Jesús · 2014 · Frontiers in Cellular Neuroscience
  63. Therapeutic strategies for tau mediated neurodegeneration
    Yasumasa Yoshiyama, Virginia M.‐Y. Lee, John Q. Trojanowski · 2012 · Journal of Neurology Neurosurgery & Psychiatry
  64. Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau
    Jean‐Philippe Courade, Rachel C. Angers, Georges Mairet‐Coello, Nathalie Pacico, Kerry L. Tyson, Daniel J. Lightwood, Rebecca Munro, David McMillan, Robert Griffin, TERRY S. BAKER et al. · 2018 · Acta Neuropathologica
  65. “Prion‐Like” Templated Misfolding in Tauopathies
    Florence Clavaguera, Isabelle Lavenir, Ben Falcon, Stephan Frank, Michel Goedert, Markus Tolnay · 2013 · Brain Pathology
  66. Emerging Roles of Astrocytes in Neuro-Vascular Unit and the Tripartite Synapse With Emphasis on Reactive Gliosis in the Context of Alzheimer’s Disease
    Liu, Cai-Yun, Yang, Yu, Ju, Wei-Na, Wang, Xu, Zhang, Hong-Liang · 2018 · Frontiers in Cellular Neuroscience
  67. In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease
    Meisl, Georg, Hidari, Eric, Allinson, Kieren, Rittman, Timothy, DeVos, Sarah L., Sanchez, Justin S., Xu, Catherine K., Duff, Karen E., Johnson, Keith A., Rowe, James B. et al. · 2021 · Science Advances
  68. Hyperphosphorylation determines both the spread and the morphology of tau pathology
    Wen Hui Hu, Xinhua Zhang, Yunn Chyn Tung, Shu-Tao Xie, Fei Liu, Khalid Iqbal · 2016 · Alzheimer s & Dementia
  69. Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis
    Raquel Maria Sanchez-Varo, Marina Mejias‐Ortega, Juan José Fernandez-Valenzuela, Cristina Nuñez‐Diaz, Laura Cáceres-Palomo, Laura Vegas‐Gomez, Elisabeth Sánchez‐Mejías, Laura Trujillo‐Estrada, Juan Antonio García‐León, Inés Moreno‐González et al. · 2022 · International Journal of Molecular Sciences
  70. Micropublications: a semantic model for claims, evidence, arguments and annotations in biomedical communications
    Tim Clark, Paolo Ciccarese, Carole Goble · 2014 · Journal of Biomedical Semantics
  71. Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease
    2022
  72. Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro
    Nobuhara, Chloe K., DeVos, Sarah L., Commins, Caitlin, Wegmann, Susanne, Moore, Benjamin D., Roe, Allyson D., Costantino, Isabel, Frosch, Matthew P., Pitstick, Rose, Carlson, George A. et al. · 2017 · The American Journal of Pathology
  73. Biophysical Insights into How Surfaces, Including Lipid Membranes, Modulate Protein Aggregation Related to Neurodegeneration
    Burke, Kathleen A., Yates, Elizabeth A., Legleiter, Justin · 2013 · Frontiers in Neurology
  74. Trem2 deletion enhances tau dispersion and pathology through microglia exosomes
    Zhu, Bing, Liu, Yan, Hwang, Spring, Archuleta, Kailey, Huang, Huijie, Campos, Alex, Murad, Rabi, Piña-Crespo, Juan, Xu, Huaxi, Huang, Timothy Y. · 2022 · Molecular Neurodegeneration
  75. Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo
    Jin Miao, Ruirui Shi, Longfei Li, Feng Chen, Yan Zhou, Yunn Chyn Tung, Wen Hui Hu, Cheng‐Xin Gong, Khalid Iqbal, Fei Liu · 2019 · Frontiers in Aging Neuroscience
  76. TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading
    Yin Xu, Shuqi Du, Jacob A. Marsh, Kanta Horie, Chihiro Sato, Andrea Ballabio, Celeste M M. Karch, David M. Holtzman, Hui Zheng · 2020 · Molecular Psychiatry
  77. Chronic neurodegenerative consequences of traumatic brain injury
    Neelima B. Chauhan · 2014 · Restorative Neurology and Neuroscience
  78. Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement
    Lee, Seung-Hye, Le Pichon, Claire E., Adolfsson, Oskar, Gafner, Valérie, Pihlgren, Maria, Lin, Han, Solanoy, Hilda, Brendza, Robert, Ngu, Hai, Foreman, Oded et al. · 2016 · Cell Reports
  79. Synaptic alterations in the rTg4510 mouse model of tauopathy
    Katherine J. Kopeikina, Manuela Polydoro, Hwan‐Ching Tai, Erich Yaeger, George A. Carlson, Rose Pitstick, Bradley T. Hyman, Tara L. Spires‐Jones · 2012 · The Journal of Comparative Neurology
  80. The prion model for progression and diversity of neurodegenerative diseases
    Barbara Elena Stopschinski, Marc I. Diamond · 2017 · The Lancet Neurology
  81. Can we prevent Alzheimer's disease? Secondary “prevention” trials in Alzheimer's disease
    María C. Carrillo, H. Robert Brashear, Veronika Logovinsky, J. Michael Ryan, Howard Feldman, Eric Siemers, Susan R. Abushakra, Dean M. Hartley, Ronald Carl Petersen, Ara S. Khachaturian et al. · 2013 · Alzheimer s & Dementia
  82. 18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons
    David S. Knopman, Clifford R. Jack, Heather J. Wiste, Emily S. Lundt, Stephen D. Weigand, Prashanthi Vemuri, Val J. Lowe, Kejal Kantarci, Jeffrey L. Gunter, Matthew L. Senjem et al. · 2014 · Neurobiology of Aging
  83. Propagation of tau pathology in Alzheimer’s disease: identification of novel therapeutic targets
    Amy M. Pooler, Manuela Polydoro, Susanne Wegmann, Samantha B. Nicholls, Tara L. Spires‐Jones, Bradley T. Hyman · 2013 · Alzheimer s Research & Therapy
  84. The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy
    Robert Siman, R. Cocca, Yina Dong · 2015 · PLoS ONE
  85. Microglia in Alzheimer’s Disease in the Context of Tau Pathology
    Juan Ramón Perea, Marta Bolós, Jesús Ávila · 2020 · Biomolecules
  86. Intrinsic connectivity networks in healthy subjects explain clinical variability in Alzheimer’s disease
    Lehmann, Manja, Madison, Cindee M., Ghosh, Pia M., Seeley, William W., Mormino, Elizabeth, Greicius, Michael D., Gorno-Tempini, Maria Luisa, Kramer, Joel H., Miller, Bruce L., Jagust, William J. et al. · 2013 · Proceedings of the National Academy of Sciences
  87. Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism
    Cooper, Joanna M., Lathuiliere, Aurelien, Migliorini, Mary, Arai, Allison L., Wani, Mashhood M., Dujardin, Simon, Muratoglu, Selen C., Hyman, Bradley T., Strickland, Dudley K. · 2021 · Journal of Biological Chemistry
  88. The Role of Microglia in the Spread of Tau: Relevance for Tauopathies
    Juan Ramón Perea, Marı́a Llorens-Martı́n, Jesús Ávila, Marta Bolós · 2018 · Frontiers in Cellular Neuroscience
  89. Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model
    Polydoro, Manuela, Dzhala, Volodymyr I., Pooler, Amy M., Nicholls, Samantha B., McKinney, A. Patrick, Sanchez, Laura, Pitstick, Rose, Carlson, George A., Staley, Kevin J., Spires-Jones, Tara L. et al. · 2014 · Acta Neuropathologica
  90. Neuronal Network Excitability in Alzheimer’s Disease: The Puzzle of Similar versus Divergent Roles of Amyloid β and Tau
    Syed Faraz Kazim, Joon Ho Seo, Riccardo Bianchi, Chloe S. Larson, Abhijeet Sharma, Robert K. S. Wong, Kirill Gorbachev, Ana C. Pereira · 2021 · eNeuro
  91. The dendritic hypothesis for Alzheimer's disease pathophysiology
    Cochran, J. Nicholas, Hall, Alicia M., Roberson, Erik D. · 2014 · Brain Research Bulletin
  92. The Role of Tau Oligomers in the Onset of Alzheimer's Disease Neuropathology
    Cárdenas-Aguayo, María del Carmen, Gómez-Virgilio, Laura, DeRosa, Steven, Meraz-Ríos, Marco Antonio · 2014 · ACS Chemical Neuroscience
  93. Alzheimer's Disease Mechanisms and Emerging Roads to Novel Therapeutics
    Sala Frigerio, Carlo, De Strooper, Bart · 2016 · Annual Review of Neuroscience
  94. Tunneling-nanotube direction determination in neurons and astrocytes
    Xiaolin Sun, Y Wang, Jiayi Zhang, Jie Tu, X-J Wang, X-D Su, Li Wang, Yan Zhang · 2012 · Cell Death and Disease
  95. In vivo characterization of the early states of the amyloid-beta network
    Sepulcre, Jorge, Sabuncu, Mert R., Becker, Alex, Sperling, Reisa, Johnson, Keith A. · 2013 · Brain
  96. Seed‐competent high‐molecular‐weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients
    Takeda, Shuko, Commins, Caitlin, DeVos, Sarah L., Nobuhara, Chloe K., Wegmann, Susanne, Roe, Allyson D., Costantino, Isabel, Fan, Zhanyun, Nicholls, Samantha B., Sherman, Alexis E. et al. · 2016 · Annals of Neurology
  97. The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
    Franzmeier, Nicolai, Rubinski, Anna, Neitzel, Julia, Ewers, Michael, The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Weiner, Michael W., Aisen, Paul, Petersen, Ronald, Jack, Clifford R., Jagust, William et al. · 2019 · Nature Communications
  98. Alzheimer disease
    Justin M. Nussbaum, Matthew E. Seward, George S. Bloom · 2013 · Prion
  99. Patient-Tailored, Connectivity-Based Forecasts of Spreading Brain Atrophy
    Jesse A. Brown, Jersey Deng, John M Neuhaus, Isabel J. Sible, Ana C. Sias, Suzee E. Lee, John Kornak, Gabe A. Marx, Anna M. Karydas, Salvatore Spina et al. · 2019 · Neuron
  100. Contribution of astrocytes to neuropathology of neurodegenerative diseases
    Çiğdem Acıoğlu, Lun Li, Stella Elkabes · 2021 · Brain Research